Climate and sustainability
As global health systems encounter increasing pressure from climate change, conflict, and displacement, long-acting technologies are emerging as a potential solution to expand treatment access for underserved populations. CELT Global Health are conducting a literature review to explore the viability of long-acting technologies, for use in low- and middle- income countries (LMICs) that are facing systemic instability and environmental disruption.
Project overview
The literature review explores the viability of long-acting technologies in displaced, climate-affected, and underserved populations.
It mainly focuses on HIV, tuberculosis (including latent TB infection), and malaria, while also drawing insights from other diseases. The analysis combines peer-reviewed evidence and grey literature from global health sources, including the World Health Organization, Medicines Patent Pool, Treatment Action Group, and others.
Objectives
The primary aims are to:
- Determine whether long-acting technologies can offer scalable, resilient alternatives to daily oral medication
- Identify barriers to long-acting technologies access and implementation in underserved settings
- Evaluate environmental and regulatory risks associated with long-acting technologies
- Illustrate evidence gaps to inform future Unitaid investment and policy work.
Awarding body
This work is supported by global health agency Unitaid.

(2020-38-LONGEVITY)
Related publications
The findings will inform Unitaid’s Access and Climate and Health Strategy, and are being prepared for internal dissemination including strategy briefings, stakeholder workshops, and meetings with global partners.