Malaria prevention in low- and middle-income countries

Malaria is a huge burden in the poorest nations, disproportionately affecting children under five and those residing in rural areas. In 2021 the WHO Africa Region was home to 95% of all malaria cases and 96% of deaths.

The Malaria Burden

  • There were 247 million global cases of malaria in 2021.
  • Malaria disproportionately affects children under five and those residing in rural areas.
  • In 2021 the WHO Africa Region was home to 95% of all malaria cases and 96% of deaths.
  • The estimated number of malaria deaths stood at 619 000 in 2021.
  • In Africa, children under 5 years of age accounted for around 80% of all malaria deaths.
  • Every minute in sub-Saharan Africa a child dies from malaria. The region accounts for approximately 93% of all malaria deaths globally.

Source: World Malaria Report 2022 (click to download)

LONGEVITY and malaria

The malaria burden can be reduced by tackling the issue of non-adherence to current malaria prevention regimens which require taking many tablets, and adding new tools to the control strategies currently available.

The LONGEVITY Project will deploy a long-acting injectable prophylactic which provides protection from malaria with just one injection a year. This will simplify drug delivery to improve adherence, reduce transmission rates and support future strategies to eliminate the disease.


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