LONGEVITY Project Blog

Stopping TB in its tracks with long-acting injectables: A war of attritionStopping TB in its tracks with long-acting injectables: A war of attrition

Stopping TB in its tracks with long-acting injectables: A war of attrition

World TB Day 2023, themed 'Yes! We can end TB!', is set to inspire a renewed sense of hope in the fight against the TB epidemic. The campaign seeks to encourage leaders to take bold steps, increase funding, adopt innovative solutions, and act faster to curb the spread of the disease.

Posted on: 23 March 2023

Community engagement – shaping the long-acting technologies pipelineCommunity engagement – shaping the long-acting technologies pipeline

Community engagement – shaping the long-acting technologies pipeline

The latest World Health Organisation (WHO) reports estimate 58 million people globally have chronic hepatitis C virus (HCV) infection, with about 1.5 million new infections occurring per year. 75% of these cases occur in low- and middle-income countries.\n\nIt is estimated that oral drugs at the point of diagnosis provide a 98% cure rate if an entire oral regimen is completed. However, in LMICs, access to medication can be complex with issues around stigma and pill burden resulting in poor completion rates.

Posted on: 28 July 2022

Developing a single-injection cure for hepatitis C virus for low- and middle-income countriesDeveloping a single-injection cure for hepatitis C virus for low- and middle-income countries

Developing a single-injection cure for hepatitis C virus for low- and middle-income countries

Dr. David Lee Thomas is a professor of medicine at the Johns Hopkins University School of Medicine. He is trained in internal medicine and infectious diseases and cares for patients with chronic viral hepatitis. Dave leads the Hepatitis C programme for the Unitaid funded LONGEVITY project for CELT.\n\nFrom 2006-2022, Dr. Thomas served as the director of the Division of Infectious Diseases and the Stanhope Bayne-Jones Professor of Medicine. He remains a Professor of Medicine in the School of Medicine and of Epidemiology in the Bloomberg School of Public Health. He is a co-director of the Centre for AIDS Research Clinical Core.\n\nFor world Hepatitis Day 2022, Dr Thomas shared his expertise on hepatitis C virus as a world-leading clinical researcher.

Posted on: 28 July 2022

Saving lives through long-acting injectable innovationSaving lives through long-acting injectable innovation

Saving lives through long-acting injectable innovation

Professor Steve Rannard is Co-director of the Centre of Excellence for Long-acting Therapeutics. Steve leads a team of chemists in developing long-acting formulations for malaria prevention. For World Malaria Day, Steve and his group spent some time to explain how their innovative technology can revolutionise malaria prevention in low- and middle-income countries.

Posted on: 24 April 2022

Reducing the burden of TB in the world’s most in need communities with long-acting injectablesReducing the burden of TB in the world’s most in need communities with long-acting injectables

Reducing the burden of TB in the world’s most in need communities with long-acting injectables

Ketho Angami is a member of the Global TB Community Advisory Board and Long-Acting Technologies Community Advisory Board. In 2016 he received the National Leadership AIDS Award in India, and also the Nagaland State Governor’s award in 2021. Ketho has been engaged in the field of community led advocacy for more than 15 years, working actively in the field of tuberculosis, HIV and viral hepatitis by holding governments accountable for preventable deaths from infectious diseases. He has been engaged with the grassroots population and generating community demands for quality of service on a human rights-based approach.

Posted on: 24 March 2022

Investing in TB prevention strategies with Long-Acting injectablesInvesting in TB prevention strategies with Long-Acting injectables

Investing in TB prevention strategies with Long-Acting injectables

Susan Swindells is Professor of Internal Medicine in the Section of Infectious Diseases at the University of Nebraska Medical Center, USA. She is a contributing investigator on TB clinical development for the LONGEVITY project. A native of England, Dr. Swindells earned her medical degree from University College London in 1977, with postgraduate training in England and at the University of Washington in Seattle. A clinician and active researcher, Dr. Swindells has many years’ experience in HIV-related translational and clinical research, with a special interest in tuberculosis co-infection.

Posted on: 24 March 2022

    Blog

    Stopping TB in its tracks with long-acting injectables: A war of attritionStopping TB in its tracks with long-acting injectables: A war of attrition

    Stopping TB in its tracks with long-acting injectables: A war of attrition

    World TB Day 2023, themed 'Yes! We can end TB!', is set to inspire a renewed sense of hope in the fight against the TB epidemic. The campaign seeks to encourage leaders to take bold steps, increase funding, adopt innovative solutions, and act faster to curb the spread of the disease.

    Posted on: 23 March 2023

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Our funding

The LONGEVITY Project is funded by Unitaid

The Unitaid logo is the organisation name written above the words

The project also involves critical partners and collaborators in the Clinton Health Access Initiative, Johns Hopkins University, Medicines Patent Pool, Tandem Nano Ltd., Treatment Action Group and the University of Nebraska Medical Center

The Clinton Health Access Initiative logo is the name with a ring of stars flying from itJohns Hopkins University logo is the Institution name under its crestThe Medicines Patent Pool logo is the organisation name to the right of three interconnecting circlesThe Tandem Nano Ltd logo is the organisation name to the right of a stylised letter T graphicThe Treatment Action Group logo is the Acronym The UNMC logo is the initialisation with the words