Prof Ian Prior

NWCR Professor of Molecular Oncology Cellular and Molecular Physiology

    Publications

    2019

    LAP-like non-canonical autophagy and evolution of endocytic vacuoles in pancreatic acinar cells (Journal article)

    De Faveri, F., Chvanov, M., Voronina, S., Moore, D., Pollock, L., Haynes, L., . . . Tepikin, A. V. (2019). LAP-like non-canonical autophagy and evolution of endocytic vacuoles in pancreatic acinar cells. AUTOPHAGY. doi:10.1080/15548627.2019.1679514

    DOI: 10.1080/15548627.2019.1679514

    Targeting centrosome amplification, an Achilles' heel of cancer (Journal article)

    Sabat-Pospiech, D., Fabian-Kolpanowicz, K., Prior, I. A., Coulson, J. M., & Fielding, A. B. (2019). Targeting centrosome amplification, an Achilles' heel of cancer. BIOCHEMICAL SOCIETY TRANSACTIONS, 47, 1209-1222. doi:10.1042/BST20190034

    DOI: 10.1042/BST20190034

    Exploiting Covalent, H-Bonding, and π–π Interactions to Design Antibacterial PDMS Interfaces That Load and Release Salicylic Acid (Journal article)

    Sorzabal Bellido, I., Diaz Fernandez, Y. A., Skelton, A. A., Susarrey Arce, A., McBride, F., Prior, I. A., . . . Raval, R. (2019). Exploiting Covalent, H-Bonding, and π–π Interactions to Design Antibacterial PDMS Interfaces That Load and Release Salicylic Acid. ACS Appl. Bio Mater.. doi:10.1021/acsabm.9b00562

    DOI: 10.1021/acsabm.9b00562

    ER stress-linked autophagy stabilizes apoptosis effector PERP and triggers its co-localization with SERCA2b at ER-plasma membrane junctions (Journal article)

    Paraoan, L. (2019). ER stress-linked autophagy stabilizes apoptosis effector PERP and triggers its co-localization with SERCA2b at ER-plasma membrane junctions. Cell Death Discovery. doi:10.1038/s41420-019-0212-4

    DOI: 10.1038/s41420-019-0212-4

    ER stress-linked autophagy stabilizes apoptosis effector PERP and triggers its co-localization with SERCA2b at ER-plasma membrane junctions. (Other)

    McDonnell, S. J., Spiller, D. G., White, M. R. H., Prior, I. A., & Paraoan, L. (2019). ER stress-linked autophagy stabilizes apoptosis effector PERP and triggers its co-localization with SERCA2b at ER-plasma membrane junctions.. In Cell death discovery (Vol. 5, pp. 132). [Electronic-eCollection]. doi:10.1038/s41420-019-0212-4

    DOI: 10.1038/s41420-019-0212-4

    Concentric lamellae - novel microanatomical structures in the articular calcified cartilage of mice (Journal article)

    Keenan, C. M., Beckett, A. J., Sutherland, H., Ranganath, L. R., Jarvis, J. C., Prior, I. A., & Gallagher, J. A. (2019). Concentric lamellae - novel microanatomical structures in the articular calcified cartilage of mice. SCIENTIFIC REPORTS, 9. doi:10.1038/s41598-019-47545-2

    DOI: 10.1038/s41598-019-47545-2

    DRP-1 functions independently of mitochondrial structural perturbations to facilitate BH3 mimetic-mediated apoptosis. (Journal article)

    Milani, M., Beckett, A. J., Al-Zebeeby, A., Luo, X., Prior, I. A., Cohen, G. M., & Varadarajan, S. (2019). DRP-1 functions independently of mitochondrial structural perturbations to facilitate BH3 mimetic-mediated apoptosis.. Cell death discovery, 5, 117. doi:10.1038/s41420-019-0199-x

    DOI: 10.1038/s41420-019-0199-x

    SuperCLEM: an accessible correlative light and electron microscopy approach for investigation of neurons and glia in vitro. (Journal article)

    Booth, D. G., Beckett, A. J., Prior, I. A., & Meijer, D. (2019). SuperCLEM: an accessible correlative light and electron microscopy approach for investigation of neurons and glia in vitro.. Biology open. doi:10.1242/bio.042085

    DOI: 10.1242/bio.042085

    Isoform-specific Ras signaling is growth factor dependent (Journal article)

    Hood, F. E., Klinger, B., Newlaczyl, A. U., Sieber, A., Dorel, M., Oliver, S. P., . . . Prior, I. A. (2019). Isoform-specific Ras signaling is growth factor dependent. MOLECULAR BIOLOGY OF THE CELL, 30(9), 1108-1117. doi:10.1091/mbc.E18-10-0676

    DOI: 10.1091/mbc.E18-10-0676

    Trypanosoma brucei colonises the tsetse gut via an immature peritrophic matrix in the proventriculus (Journal article)

    Rose, C., Dyer, N., Casas-Sanchez, A., Beckett, A., Solórzano, C., Middlehurst, B., . . . Acosta-Serrano, Á. (2019). Trypanosoma brucei colonises the tsetse gut via an immature peritrophic matrix in the proventriculus. doi:10.1101/513689

    DOI: 10.1101/513689

    2018

    Fibroblast Growth Factor 2 lethally sensitizes cancer cells to stress-targeted therapeutic inhibitors. (Journal article)

    Dias, M. H., Fonseca, C. S., Zeidler, J. D., Albuquerque, L. L., da Silva, M. S., Lopes-Cararo, E., . . . Armelin, H. A. (2018). Fibroblast Growth Factor 2 lethally sensitizes cancer cells to stress-targeted therapeutic inhibitors.. Molecular oncology. doi:10.1002/1878-0261.12402

    DOI: 10.1002/1878-0261.12402

    RAS variant signalling (Journal article)

    Mo, S. P., Coulson, J. M., & Prior, I. A. (2018). RAS variant signalling. BIOCHEMICAL SOCIETY TRANSACTIONS, 46, 1325-1332. doi:10.1042/BST20180173

    DOI: 10.1042/BST20180173

    Eps8 is a convergence point integrating EGFR and integrin trafficking and crosstalk (Journal article)

    Paul, N., Thomas, J., Maldonado, H., Wolanska, K., Koper, E., Humphries, J., . . . Morgan, M. (2018). Eps8 is a convergence point integrating EGFR and integrin trafficking and crosstalk. doi:10.1101/405043

    DOI: 10.1101/405043

    Integrin alpha V beta 6-EGFR crosstalk regulates bidirectional force transmission and controls breast cancer invasion (Journal article)

    Thomas, J. R., Moore, K. M., Sproat, C., Mo, S., Wolanska, K. I., Maldonado, H., . . . Morgan, M. R. (2019). Integrin alpha V beta 6-EGFR crosstalk regulates bidirectional force transmission and controls breast cancer invasion. INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY, 100(4), A39. Retrieved from http://gateway.webofknowledge.com/

    Long-Chain n-3 Fatty Acids Attenuate Oncogenic KRas-Driven Proliferation by Altering Plasma Membrane Nanoscale Proteolipid Composition (Journal article)

    Fuentes, N. R., Mlih, M., Barhoumi, R., Fan, Y. -Y., Hardin, P., Steele, T. J., . . . Chapkin, R. S. (2018). Long-Chain n-3 Fatty Acids Attenuate Oncogenic KRas-Driven Proliferation by Altering Plasma Membrane Nanoscale Proteolipid Composition. CANCER RESEARCH, 78(14), 3899-3912. doi:10.1158/0008-5472.CAN-18-0324

    DOI: 10.1158/0008-5472.CAN-18-0324

    The deubiquitylase USP15 regulates topoisomerase II alpha to maintain genome integrity (Journal article)

    Fielding, A. B., Concannon, M., Darling, S., Rusilowicz-Jones, E. V., Sacco, J. J., Prior, I. A., . . . Coulson, J. M. (2018). The deubiquitylase USP15 regulates topoisomerase II alpha to maintain genome integrity. ONCOGENE, 37(17), 2326-2342. doi:10.1038/s41388-017-0092-0

    DOI: 10.1038/s41388-017-0092-0

    2017

    New Perspectives, Opportunities, and Challenges in Exploring the Human Protein Kinome (Journal article)

    Wilson, L. J., Linley, A., Hammond, D. E., Hood, F. E., Coulson, J. M., MacEwan, D. J., . . . Prior, I. A. (2018). New Perspectives, Opportunities, and Challenges in Exploring the Human Protein Kinome. CANCER RESEARCH, 78(1), 15-29. doi:10.1158/0008-5472.CAN-17-2291

    DOI: 10.1158/0008-5472.CAN-17-2291

    Regulation of the cell cycle and centrosome biology by deubiquitylases (Journal article)

    Darling, S., Fielding, A. B., Sabat-Pospiech, D., Prior, I. A., & Coulson, J. M. (2017). Regulation of the cell cycle and centrosome biology by deubiquitylases. BIOCHEMICAL SOCIETY TRANSACTIONS, 45, 1125-1136. doi:10.1042/BST20170087

    DOI: 10.1042/BST20170087

    Modulating Protein-Protein Interactions of the Mitotic Polo-like Kinases to Target Mutant KRAS (Journal article)

    Narvaez, A. J., Ber, S., Crooks, A., Emery, A., Hardwick, B., Almeida, E. G., . . . Venkitaraman, A. R. (2017). Modulating Protein-Protein Interactions of the Mitotic Polo-like Kinases to Target Mutant KRAS. CELL CHEMICAL BIOLOGY, 24(8), 1017-+. doi:10.1016/j.chembiol.2017.07.009

    DOI: 10.1016/j.chembiol.2017.07.009

    Modular approach for bimodal antibacterial surfaces combining photo-switchable activity and sustained biocidal release (Journal article)

    Pallavicini, P., Bassi, B., Chirico, G., Collini, M., Dacarro, G., Fratini, E., . . . Fernandez, Y. A. D. (2017). Modular approach for bimodal antibacterial surfaces combining photo-switchable activity and sustained biocidal release. SCIENTIFIC REPORTS, 7. doi:10.1038/s41598-017-05693-3

    DOI: 10.1038/s41598-017-05693-3

    Conserved effects and altered trafficking of Cetuximab antibodies conjugated to gold nanoparticles with precise control of their number and orientation (Journal article)

    Garcia-Fernandez, L., Garcia-Pardo, J., Tort, O., Prior, I., Brust, M., Casals, E., . . . Puntes, V. F. (2017). Conserved effects and altered trafficking of Cetuximab antibodies conjugated to gold nanoparticles with precise control of their number and orientation. NANOSCALE, 9(18), 6111-6121. doi:10.1039/c7nr00947j

    DOI: 10.1039/c7nr00947j

    Exploring the protein-protein interactions of the p53 apoptosis effector protein PERP (Conference Paper)

    McDonnell, S. J., Prior, I., & Paraoan, L. I. (2017). Exploring the protein-protein interactions of the p53 apoptosis effector protein PERP. In INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE Vol. 58. Retrieved from http://gateway.webofknowledge.com/

    Microtubule organization within mitotic spindles revealed by serial block face scanning electron microscopy and image analysis (Journal article)

    Nixon, F. M., Honnor, T. R., Clarke, N. I., Starling, G. P., Beckett, A. J., Johansen, A. M., . . . Royle, S. J. (2017). Microtubule organization within mitotic spindles revealed by serial block face scanning electron microscopy and image analysis. JOURNAL OF CELL SCIENCE, 130(10), 1845-1855. doi:10.1242/jcs.203877

    DOI: 10.1242/jcs.203877

    Serial block-face scanning electron microscopy applied to study the trafficking of 8D3-coated gold nanoparticles at the blood-brain barrier (Journal article)

    Cabezon, I., Auge, E., Bosch, M., Beckett, A. J., Prior, I. A., Pelegri, C., & Vilaplana, J. (2017). Serial block-face scanning electron microscopy applied to study the trafficking of 8D3-coated gold nanoparticles at the blood-brain barrier. HISTOCHEMISTRY AND CELL BIOLOGY, 148(1), 3-12. doi:10.1007/s00418-017-1553-9

    DOI: 10.1007/s00418-017-1553-9

    Quantification of spatiotemporal patterns of Ras isoform expression during development (Journal article)

    Newlaczyl, A. U., Coulson, J. M., & Prior, I. A. (2017). Quantification of spatiotemporal patterns of Ras isoform expression during development. SCIENTIFIC REPORTS, 7. doi:10.1038/srep41297

    DOI: 10.1038/srep41297

    2016

    3D-CLEM Reveals that a Major Portion of Mitotic Chromosomes Is Not Chromatin. (Journal article)

    Booth, D. G., Beckett, A. J., Molina, O., Samejima, I., Masumoto, H., Kouprina, N., . . . Earnshaw, W. C. (2016). 3D-CLEM Reveals that a Major Portion of Mitotic Chromosomes Is Not Chromatin. MOLECULAR CELL, 64(4), 790-802. doi:10.1016/j.molcel.2016.10.009

    DOI: 10.1016/j.molcel.2016.10.009

    The endoplasmic reticulum remains functionally connected by vesicular transport after its fragmentation in cells expressing Z-alpha(1)-antitrypsin (Journal article)

    Dickens, J. A., Ordonez, A., Chambers, J. E., Beckett, A. J., Patel, V., Malzer, E., . . . Marciniak, S. J. (2016). The endoplasmic reticulum remains functionally connected by vesicular transport after its fragmentation in cells expressing Z-alpha(1)-antitrypsin. FASEB JOURNAL, 30(12), 4083-4097. doi:10.1096/fj.201600430R

    DOI: 10.1096/fj.201600430R

    Feedback activation of neurofibromin terminates growth factor-induced Ras activation (Journal article)

    Hennig, A., Markwart, R., Wolff, K., Schubert, K., Cui, Y., Prior, I. A., . . . Rubio, I. (2016). Feedback activation of neurofibromin terminates growth factor-induced Ras activation. CELL COMMUNICATION AND SIGNALING, 14. doi:10.1186/s12964-016-0128-z

    DOI: 10.1186/s12964-016-0128-z

    2015

    The role of Ca2+ influx in endocytic vacuole formation in pancreatic acinar cells (Journal article)

    Voronina, S., Collier, D., Chvanov, M., Middlehurst, B., Beckett, A. J., Prior, I. A., . . . Tepikin, A. V. (2015). The role of Ca2+ influx in endocytic vacuole formation in pancreatic acinar cells. BIOCHEMICAL JOURNAL, 465, 405-412. doi:10.1042/BJ20140398

    DOI: 10.1042/BJ20140398

    Absolute Quantification of Endogenous Ras Isoform Abundance (Journal article)

    Mageean, C. J., Griffiths, J. R., Smith, D. L., Clague, M. J., & Prior, I. A. (2015). Absolute Quantification of Endogenous Ras Isoform Abundance. PLOS ONE, 10(11). doi:10.1371/journal.pone.0142674

    DOI: 10.1371/journal.pone.0142674

    Comparative proteomic analysis of compartmentalised Ras signalling (Journal article)

    Hernandez-Valladares, M., & Prior, I. A. (2015). Comparative proteomic analysis of compartmentalised Ras signalling. SCIENTIFIC REPORTS, 5. doi:10.1038/srep17307

    DOI: 10.1038/srep17307

    Differential Reprogramming of Isogenic Colorectal Cancer Cells by Distinct Activating KRAS Mutations (Journal article)

    Hammond, D. E., Hammond, D. E., Mageean, C. J., Rusilowicz, E. V., Wickenden, J. A., Clague, M. J., & Priorr, I. A. (2015). Differential Reprogramming of Isogenic Colorectal Cancer Cells by Distinct Activating KRAS Mutations. JOURNAL OF PROTEOME RESEARCH, 14(3), 1535-1546. doi:10.1021/pr501191a

    DOI: 10.1021/pr501191a

    Electron microscopy methods for studying plasma membranes. (Journal article)

    Beckett, A. J., & Prior, I. A. (2015). Electron microscopy methods for studying plasma membranes.. Methods in molecular biology (Clifton, N.J.), 1232, 137-151. doi:10.1007/978-1-4939-1752-5_12

    DOI: 10.1007/978-1-4939-1752-5_12

    The mesh is a network of microtubule connectors that stabilizes individual kinetochore fibers of the mitotic spindle (Journal article)

    Nixon, F. M., Gutierrez-Caballero, C., Hood, F. E., Booth, D. G., Prior, I. A., & Royle, S. J. (2015). The mesh is a network of microtubule connectors that stabilizes individual kinetochore fibers of the mitotic spindle. ELIFE, 4. doi:10.7554/eLife.07635

    DOI: 10.7554/eLife.07635

    2014

    Differential network reprogramming by distinct activating K-Ras mutations (Conference Paper)

    Hammond, D. E., Mageean, C. J., Rusilowicz, E. V., Clague, M. J., & Prior, I. A. (2014). Differential network reprogramming by distinct activating K-Ras mutations. In MOLECULAR CANCER RESEARCH Vol. 12. doi:10.1158/1557-3125.RASONC14-B30

    DOI: 10.1158/1557-3125.RASONC14-B30

    Tissue- and isoform-specific Ras expression during development (Conference Paper)

    Newlaczyl, A. U., Coulson, J. M., & Prior, I. A. (2014). Tissue- and isoform-specific Ras expression during development. In CANCER RESEARCH Vol. 74. doi:10.1158/1538-7445.AM2014-4449

    DOI: 10.1158/1538-7445.AM2014-4449

    Decoding RAS isoform and codon-specific signalling (Journal article)

    Newlaczyl, A. U., Hood, F. E., Coulson, J. M., & Prior, I. A. (2014). Decoding RAS isoform and codon-specific signalling. Biochem. Soc. Trans., 4, 7426.

    Decoding RAS isoform and codon-specific signalling (Journal article)

    Newlaczyl, A. U., Hood, F. E., Coulson, J. M., & Prior, I. A. (2014). Decoding RAS isoform and codon-specific signalling. BIOCHEMICAL SOCIETY TRANSACTIONS, 42, 742-746. doi:10.1042/BST20140057

    DOI: 10.1042/BST20140057

    Plasticity of Mammary Cell Boundaries Governed by EGF and Actin Remodeling (Journal article)

    Tang, W. Y. Y., Beckett, A. J., Prior, I. A., Coulson, J. M., Urbe, S., & Clague, M. J. (2014). Plasticity of Mammary Cell Boundaries Governed by EGF and Actin Remodeling. CELL REPORTS, 8(6), 1722-1730. doi:10.1016/j.celrep.2014.08.026

    DOI: 10.1016/j.celrep.2014.08.026

    Quantitative Proteomic Analysis of Compartmentalized Signaling Networks (Journal article)

    Hernandez-Valladares, M., Aran, V., & Prior, I. A. (2014). Quantitative Proteomic Analysis of Compartmentalized Signaling Networks. ENDOSOME SIGNALING, PT B, 535, 309-325. doi:10.1016/B978-0-12-397925-4.00018-3

    DOI: 10.1016/B978-0-12-397925-4.00018-3

    The neuroendocrine phenotype of gastric myofibroblasts and its loss with cancer progression (Journal article)

    Balabanova, S., Holmberg, C., Steele, I., Ebrahimi, B., Rainbow, L., Burdyga, T., . . . Varro, A. (2014). The neuroendocrine phenotype of gastric myofibroblasts and its loss with cancer progression. CARCINOGENESIS, 35(8), 1798-1806. doi:10.1093/carcin/bgu086

    DOI: 10.1093/carcin/bgu086

    The neuroendocrine phenotype of gastric myofibroblasts and its loss with cancer progression (Journal article)

    Balabanova, S., Holmberg, C., Steele, I., Ebrahimi, B., Rainbow, L., Burdyga, T., . . . Varro, A. (2014). The neuroendocrine phenotype of gastric myofibroblasts and its loss with cancer progression. Carcinogenesis, 35(8), 1798-1806. doi:10.1093/carcin/bgu086

    DOI: 10.1093/carcin/bgu086

    2013

    Erratum: Ras palmitoylation is necessary for N-Ras activation and signal propagation in growth factor signalling (Biochemical Journal (2013) 454 (323-332)) (Journal article)

    Song, S. P., Hennig, A., Schubert, K., Markwart, R., Schmidt, P., Prior, I. A., . . . Rubio, I. (2013). Erratum: Ras palmitoylation is necessary for N-Ras activation and signal propagation in growth factor signalling (Biochemical Journal (2013) 454 (323-332)). Biochemical Journal, 455(1), 131.

    CD317/tetherin is an organiser of membrane microdomains (Journal article)

    Billcliff, P. G., Rollason, R., Prior, I., Owen, D. M., Gaus, K., & Banting, G. (2013). CD317/tetherin is an organiser of membrane microdomains. JOURNAL OF CELL SCIENCE, 126(7), 1553-1564. doi:10.1242/jcs.112953

    DOI: 10.1242/jcs.112953

    Compartmentalized Ras signaling differentially contributes to phenotypic outputs (Journal article)

    Aran, V., & Prior, I. A. (2013). Compartmentalized Ras signaling differentially contributes to phenotypic outputs. CELLULAR SIGNALLING, 25(9), 1748-1753. doi:10.1016/j.cellsig.2013.05.004

    DOI: 10.1016/j.cellsig.2013.05.004

    Oncogenic K-ras segregates at spatially distinct plasma membrane signaling platforms according to its phosphorylation status (Journal article)

    Barcelo, C., Paco, N., Beckett, A. J., Alvarez-Moya, B., Garrido, E., Gelabert, M., . . . Agell, N. (2013). Oncogenic K-ras segregates at spatially distinct plasma membrane signaling platforms according to its phosphorylation status. JOURNAL OF CELL SCIENCE, 126(20), 4553-4559. doi:10.1242/jcs.123737

    DOI: 10.1242/jcs.123737

    Pronounced in vivo hemoglobin polymerization in red blood cells of Gulf toadfish: a general role for hemoglobin aggregation in vertebrate hemoparasite defense? (Journal article)

    Koldkjaer, P., McDonald, M. D., Prior, I., & Berenbrink, M. (2013). Pronounced in vivo hemoglobin polymerization in red blood cells of Gulf toadfish: a general role for hemoglobin aggregation in vertebrate hemoparasite defense?. AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY, 305(10), R1190-R1199. doi:10.1152/ajpregu.00246.2013

    DOI: 10.1152/ajpregu.00246.2013

    Ras palmitoylation is necessary for N-Ras activation and signal propagation in growth factor signalling (Journal article)

    Song, S. -P., Hennig, A., Schubert, K., Markwart, R., Schmidt, P., Prior, I. A., . . . Rubio, I. (2013). Ras palmitoylation is necessary for N-Ras activation and signal propagation in growth factor signalling. BIOCHEMICAL JOURNAL, 454, 323-332. doi:10.1042/BJ20121799

    DOI: 10.1042/BJ20121799

    Specific removal of TACC3-ch-TOG-clathrin at metaphase deregulates kinetochore fiber tension (Journal article)

    Cheeseman, L. P., Harry, E. F., McAinsh, A. D., Prior, I. A., & Royle, S. J. (2013). Specific removal of TACC3-ch-TOG-clathrin at metaphase deregulates kinetochore fiber tension. JOURNAL OF CELL SCIENCE, 126(9), 2102-2113. doi:10.1242/jcs.124834

    DOI: 10.1242/jcs.124834

    Studying Kinetochore-Fiber Ultrastructure Using Correlative Light-Electron Microscopy (Journal article)

    Booth, D. G., Cheeseman, L. P., Prior, I. A., & Royle, S. J. (2013). Studying Kinetochore-Fiber Ultrastructure Using Correlative Light-Electron Microscopy. MICROTUBULES, IN VITRO, 2ND EDITION, 115, 327-342. doi:10.1016/B978-0-12-407757-7.00020-7

    DOI: 10.1016/B978-0-12-407757-7.00020-7

    The role of palmitoylation in regulating Ras localization and function (Journal article)

    Eisenberg, S., Laude, A. J., Beckett, A. J., Mageean, C. J., Aran, V., Hernandez-Valladares, M., . . . Prior, I. A. (2013). The role of palmitoylation in regulating Ras localization and function. BIOCHEMICAL SOCIETY TRANSACTIONS, 41, 79-83. doi:10.1042/BST20120268

    DOI: 10.1042/BST20120268

    2012

    A Comprehensive Survey of Ras Mutations in Cancer (Journal article)

    Prior, I. A., Lewis, P. D., & Mattos, C. (2012). A Comprehensive Survey of Ras Mutations in Cancer. CANCER RESEARCH, 72(10), 2457-2467. doi:10.1158/0008-5472.CAN-11-2612

    DOI: 10.1158/0008-5472.CAN-11-2612

    Global Snapshot of the Influence of Endocytosis upon EGF Receptor Signaling Output (Journal article)

    Omerovic, J., Hammond, D. E., Prior, I. A., & Clague, M. J. (2012). Global Snapshot of the Influence of Endocytosis upon EGF Receptor Signaling Output. Journal of Proteome Research, 11(11), 5157-5166. doi:10.1021/pr3007304

    DOI: 10.1021/pr3007304

    Global Snapshot of the Influence of Endocytosis upon EGF Receptor Signaling Output (Journal article)

    Omerovic, J., Hammond, D. E., Prior, I. A., & Clague, M. J. (2012). Global Snapshot of the Influence of Endocytosis upon EGF Receptor Signaling Output. JOURNAL OF PROTEOME RESEARCH, 11(11), 5157-5166. doi:10.1021/pr3007304

    DOI: 10.1021/pr3007304

    Mercaptocarborane-Capped Gold Nanoparticles: Electron Pools and Ion Traps with Switchable Hydrophilicity (Journal article)

    Cioran, A. M., Musteti, A. D., Teixidor, F., Krpetic, Z., Prior, I. A., He, Q., . . . Vinas, C. (2012). Mercaptocarborane-Capped Gold Nanoparticles: Electron Pools and Ion Traps with Switchable Hydrophilicity. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 134(1), 212-221. doi:10.1021/ja203367h

    DOI: 10.1021/ja203367h

    Putting signalling into context (Journal article)

    Prior, I. A. (2012). Putting signalling into context. SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY, 23(2), 125. doi:10.1016/j.semcdb.2012.02.008

    DOI: 10.1016/j.semcdb.2012.02.008

    Ras trafficking, localization and compartmentalized signalling (Journal article)

    Prior, I. A., & Hancock, J. F. (2012). Ras trafficking, localization and compartmentalized signalling. SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY, 23(2), 145-153. doi:10.1016/j.semcdb.2011.09.002

    DOI: 10.1016/j.semcdb.2011.09.002

    Transport of Fibroblast Growth Factor 2 in the Pericellular Matrix Is Controlled by the Spatial Distribution of Its Binding Sites in Heparan Sulfate (Journal article)

    Duchesne, L., Octeau, V., Bearon, R. N., Beckett, A., Prior, I. A., Lounis, B., & Fernig, D. G. (2012). Transport of Fibroblast Growth Factor 2 in the Pericellular Matrix Is Controlled by the Spatial Distribution of Its Binding Sites in Heparan Sulfate. PLOS BIOLOGY, 10(7). doi:10.1371/journal.pbio.1001361

    DOI: 10.1371/journal.pbio.1001361

    2011

    A TACC3/ch-TOG/clathrin complex stabilises kinetochore fibres by inter-microtubule bridging (Journal article)

    Booth, D. G., Hood, F. E., Prior, I. A., & Royle, S. J. (2011). A TACC3/ch-TOG/clathrin complex stabilises kinetochore fibres by inter-microtubule bridging. EMBO JOURNAL, 30(5), 906-919. doi:10.1038/emboj.2011.15

    DOI: 10.1038/emboj.2011.15

    Acrylate-Facilitated Cellular Uptake of Gold Nanoparticles (Journal article)

    Krpetic, Z., Nativo, P., Prior, I. A., & Brust, M. (2011). Acrylate-Facilitated Cellular Uptake of Gold Nanoparticles. SMALL, 7(14), 1982-1986. doi:10.1002/smll.201100462

    DOI: 10.1002/smll.201100462

    Aurora A kinase activity is required for localisation of TACC3/ch-TOG/clathrin inter-microtubule bridges (Journal article)

    Cheeseman, L. P., Booth, D. G., Hood, F. E., Prior, I. A., & Royle, S. J. (2011). Aurora A kinase activity is required for localisation of TACC3/ch-TOG/clathrin inter-microtubule bridges. Commun. Integr. Biol., 4(4), 409-412.

    Intracellular mapping with SERS-encoded gold nanostars (Journal article)

    Rodriguez-Lorenzo, L., Krpetic, Z., Barbosa, S., Alvarez-Puebla, R. A., Liz-Marzan, L. M., Prior, I. A., & Brust, M. (2011). Intracellular mapping with SERS-encoded gold nanostars. INTEGRATIVE BIOLOGY, 3(9), 922-926. doi:10.1039/c1ib00029b

    DOI: 10.1039/c1ib00029b

    Magnetic CoPt nanoparticles as MRI contrast agent for transplanted neural stem cells detection (Journal article)

    Meng, X., Seton, H. C., Lu, L. T., Prior, I. A., Thanh, N. T. K., & Song, B. (2011). Magnetic CoPt nanoparticles as MRI contrast agent for transplanted neural stem cells detection. NANOSCALE, 3(3), 977-984. doi:10.1039/c0nr00846j

    DOI: 10.1039/c0nr00846j

    Negotiation of Intracellular Membrane Barriers by TAT-Modified Gold Nanoparticles (Journal article)

    Krpetic, Z., Saleemi, S., Prior, I. A., See, V., Qureshi, R., & Brust, M. (2011). Negotiation of Intracellular Membrane Barriers by TAT-Modified Gold Nanoparticles. ACS NANO, 5(6), 5195-5201. doi:10.1021/nn201369k

    DOI: 10.1021/nn201369k

    Raft Protein Clustering Alters N-Ras Membrane Interactions and Activation Pattern (Journal article)

    Eisenberg, S., Beckett, A. J., Prior, I. A., Dekker, F. J., Hedberg, C., Waldmann, H., . . . Henis, Y. I. (2011). Raft Protein Clustering Alters N-Ras Membrane Interactions and Activation Pattern. MOLECULAR AND CELLULAR BIOLOGY, 31(19), 3938-3952. doi:10.1128/MCB.05570-11

    DOI: 10.1128/MCB.05570-11

    2010

    Ultrastructural examination of tissue in a patient with alkaptonuric arthropathy reveals a distinct pattern of binding of ochronotic pigment (Journal article)

    Taylor, A. M., Wlodarski, B., Prior, I. A., Wilson, P. J. M., Jarvis, J. C., Ranganath, L. R., & Gallagher, J. A. (2010). Ultrastructural examination of tissue in a patient with alkaptonuric arthropathy reveals a distinct pattern of binding of ochronotic pigment. Rheumatology, 49(7), 1412-1414. doi:10.1093/rheumatology/keq027

    DOI: 10.1093/rheumatology/keq027

    Highly Stable Dextran-Coated Quantum Dots for Biomolecular Detection and Cellular Imaging (Journal article)

    Wilson, R., Spiller, D. G., Beckett, A., Prior, I. A., & See, V. (2010). Highly Stable Dextran-Coated Quantum Dots for Biomolecular Detection and Cellular Imaging. CHEMISTRY OF MATERIALS, 22(23), 6361-6369. doi:10.1021/cm1023635

    DOI: 10.1021/cm1023635

    Inflicting Controlled Nonthermal Damage to Subcellular Structures by Laser-Activated Gold Nanoparticles (Journal article)

    Krpetic, Z., Nativo, P., See, V., Prior, I. A., Brust, M., & Volk, M. (2010). Inflicting Controlled Nonthermal Damage to Subcellular Structures by Laser-Activated Gold Nanoparticles. NANO LETTERS, 10(11), 4549-4554. doi:10.1021/nl103142t

    DOI: 10.1021/nl103142t

    Inflicting Controlled Nonthermal Damage to Subcellular Structures by Laser-Activated Gold Nanoparticles (Journal article)

    Krpetić, Z., Nativo, P., Sée, V., Prior, I. A., Brust, M., & Volk, M. (2010). Inflicting Controlled Nonthermal Damage to Subcellular Structures by Laser-Activated Gold Nanoparticles. Nano Letters, 10(11), 4549-4554. doi:10.1021/nl103142t

    DOI: 10.1021/nl103142t

    Laser-induced Delivery of Gold Nanoparticles into Living Cells (Chapter)

    Nativo, P., Brust, M., See, V., Prior, I., & Volk, M. (2010). Laser-induced Delivery of Gold Nanoparticles into Living Cells. In B. Wyborn (Ed.), Central Laser Facility Annual Report 2008/09 (pp. 190-192). Didcot: Science and Technology Facilities Council.

    Phosphatome profiling reveals PTPN2, PTPRJ and PTEN as potent negative regulators of PKB/Akt activation in Ras-mutated cancer cells (Journal article)

    Omerovic, J., Clague, M. J., & Prior, I. A. (2010). Phosphatome profiling reveals PTPN2, PTPRJ and PTEN as potent negative regulators of PKB/Akt activation in Ras-mutated cancer cells. BIOCHEMICAL JOURNAL, 426, 65-72. doi:10.1042/BJ20091413

    DOI: 10.1042/BJ20091413

    Regulatory activity of polyunsaturated fatty acids in T-cell signaling (Journal article)

    Kim, W., Khan, N. A., McMurray, D. N., Prior, I. A., Wang, N., & Chapkin, R. S. (2010). Regulatory activity of polyunsaturated fatty acids in T-cell signaling. PROGRESS IN LIPID RESEARCH, 49(3), 250-261. doi:10.1016/j.plipres.2010.01.002

    DOI: 10.1016/j.plipres.2010.01.002

    Ultrastructural examination of tissue in a patient with alkaptonuric arthropathy reveals a distinct pattern of binding of ochronotic pigment (Journal article)

    Taylor, A. M., Wlodarski, B., Prior, I. A., Wilson, P. J. M., Jarvis, J. C., Ranganath, L. R., & Gallagher, J. A. (2010). Ultrastructural examination of tissue in a patient with alkaptonuric arthropathy reveals a distinct pattern of binding of ochronotic pigment. RHEUMATOLOGY, 49(7), 1412-1414. doi:10.1093/rheumatology/keq027

    DOI: 10.1093/rheumatology/keq027

    2009

    Ribosome-free Terminals of Rough ER Allow Formation of STIM1 Puncta and Segregation of STIM1 from IP3 Receptors (Journal article)

    Lur, G., Haynes, L. P., Prior, I. A., Gerasimenko, O. V., Feske, S., Petersen, O. H., . . . Tepikin, A. V. (2009). Ribosome-free Terminals of Rough ER Allow Formation of STIM1 Puncta and Segregation of STIM1 from IP3 Receptors. CURRENT BIOLOGY, 19(19), 1648-1653. doi:10.1016/j.cub.2009.07.072

    DOI: 10.1016/j.cub.2009.07.072

    Cathepsin L Digestion of Nanobioconjugates upon Endocytosis (Journal article)

    See, V., Free, P., Cesbron, Y., Nativo, P., Shaheen, U., Rigden, D. J., . . . Levy, R. (2009). Cathepsin L Digestion of Nanobioconjugates upon Endocytosis. ACS NANO, 3(9), 2461-2468. doi:10.1021/nn9006994

    DOI: 10.1021/nn9006994

    Connexin expression and gap junctional coupling in human cumulus cells: contribution to embryo quality (Journal article)

    Wang, H. -X., Tong, D., El-Gehani, F., Tekpetey, F. R., & Kidder, G. M. (2009). Connexin expression and gap junctional coupling in human cumulus cells: contribution to embryo quality. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE, 13(5), 972-984. doi:10.1111/j.1582-4934.2008.00373.x

    DOI: 10.1111/j.1582-4934.2008.00373.x

    Three-dimensional electron microscopic reconstruction of intracellular organellar arrangements in vascular smooth muscle--further evidence of nanospaces and contacts. (Journal article)

    Tong, W. C., Sweeney, M., Jones, C. J. P., Zhang, H., O'Neill, S. C., Prior, I., & Taggart, M. J. (2009). Three-dimensional electron microscopic reconstruction of intracellular organellar arrangements in vascular smooth muscle--further evidence of nanospaces and contacts.. Journal of cellular and molecular medicine, 13(5), 995-998. doi:10.1111/j.1582-4934.2009.00770.x

    DOI: 10.1111/j.1582-4934.2009.00770.x

    Compartmentalized signalling: cAMP, calcium and Ras (Journal article)

    Prior, I. A. (2009). Compartmentalized signalling: cAMP, calcium and Ras. FEBS JOURNAL, 276(7), 1789. doi:10.1111/j.1742-4658.2009.06925.x

    DOI: 10.1111/j.1742-4658.2009.06925.x

    A reliable method for attaching biological molecules to layer-by-layer self-assemblies (Journal article)

    Wilson, R., Mehrabi, M., Prior, I. A., Beckett, A., & Hutchinson, A. (2009). A reliable method for attaching biological molecules to layer-by-layer self-assemblies. CHEMICAL COMMUNICATIONS, (18), 2487-2489. doi:10.1039/b822688a

    DOI: 10.1039/b822688a

    Compartmentalized signalling: Ras proteins and signalling nanoclusters (Journal article)

    Omerovic, J., & Prior, I. A. (2009). Compartmentalized signalling: Ras proteins and signalling nanoclusters. FEBS JOURNAL, 276(7), 1817-1825. doi:10.1111/j.1742-4658.2009.06928.x

    DOI: 10.1111/j.1742-4658.2009.06928.x

    Ras acylation, compartmentalization and signaling nanoclusters (Review) (Journal article)

    Henis, Y. I., Hancock, J. F., & Prior, I. A. (2009). Ras acylation, compartmentalization and signaling nanoclusters (Review). MOLECULAR MEMBRANE BIOLOGY, 26(1-2), 80-92. doi:10.1080/09687680802649582

    DOI: 10.1080/09687680802649582

    Three-dimensional electron microscopic reconstruction of sarcoplasmic reticular arrangement in vascular smooth muscle with respect to mitochondria and the nucleus - further evidence of nanospaces and contacts (Journal article)

    Tong, W. C., Sweeney, M., Jones, C. J. P., Zhang, H., O'Neill, S. C., Prior, I., & Taggart, M. J. (2009). Three-dimensional electron microscopic reconstruction of sarcoplasmic reticular arrangement in vascular smooth muscle with respect to mitochondria and the nucleus - further evidence of nanospaces and contacts. J. Cellular Mol. Med., in press.

    Variant shape growth of nanoparticles of metallic Fe-Pt, Fe-Pd and Fe-Pt-Pd alloys (Journal article)

    Ung, D., Tung, L. D., Caruntu, G., Delaportas, D., Alexandrou, I., Prior, I. A., & Thanh, N. T. K. (2009). Variant shape growth of nanoparticles of metallic Fe-Pt, Fe-Pd and Fe-Pt-Pd alloys. CRYSTENGCOMM, 11(7), 1309-1316. doi:10.1039/b823290n

    DOI: 10.1039/b823290n

    2008

    S-nitrosylation of syntaxin 1 at Cys(145) is a regulatory switch controlling Munc18-1 binding (Journal article)

    Palmer, Z. J., Duncan, R. R., Johnson, J. R., Lian, L. -Y., Mello, L. V., Booth, D., . . . Morgan, A. (2008). S-nitrosylation of syntaxin 1 at Cys(145) is a regulatory switch controlling Munc18-1 binding. BIOCHEMICAL JOURNAL, 413, 479-491. doi:10.1042/BJ20080069

    DOI: 10.1042/BJ20080069

    Docosahexaenoic acid alters the size and distribution of cell surface microdomains (Journal article)

    Chapkin, R. S., Wang, N., Fan, Y. -Y., Lupton, J. R., & Prior, I. A. (2008). Docosahexaenoic acid alters the size and distribution of cell surface microdomains. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES, 1778(2), 466-471. doi:10.1016/j.bbamem.2007.11.003

    DOI: 10.1016/j.bbamem.2007.11.003

    Palmitoylation and localisation of RAS isoforms are modulated by the hypervariable linker domain (Journal article)

    Laude, A. J., & Prior, I. A. (2008). Palmitoylation and localisation of RAS isoforms are modulated by the hypervariable linker domain. JOURNAL OF CELL SCIENCE, 121(4), 421-427. doi:10.1242/jcs.020107

    DOI: 10.1242/jcs.020107

    Ras isoform abundance and signalling in human cancer cell lines (Journal article)

    Omerovic, J., Hammond, D. E., Clague, M. J., & Prior, I. A. (2008). Ras isoform abundance and signalling in human cancer cell lines. ONCOGENE, 27(19), 2754-2762. doi:10.1038/sj.onc.1210925

    DOI: 10.1038/sj.onc.1210925

    Uptake and intracellular fate of surface-modified gold nanoparticles (Journal article)

    Nativo, P., Prior, I. A., & Brust, M. (2008). Uptake and intracellular fate of surface-modified gold nanoparticles. ACS NANO, 2(8), 1639-1644. doi:10.1021/nn800330a

    DOI: 10.1021/nn800330a

    2007

    A simple method for preparing spectrally encoded magnetic beads for multiplexed detection (Journal article)

    Wilson, R., Spiller, D. G., Prior, I. A., Veltkamp, K. J., & Hutchinson, A. (2007). A simple method for preparing spectrally encoded magnetic beads for multiplexed detection. ACS NANO, 1(5), 487-493. doi:10.1021/nn700289m

    DOI: 10.1021/nn700289m

    Activation of trypsinogen in large endocytic vacuoles of pancreatic acinar cells (Journal article)

    Sherwood, M. W., Prior, I. A., Voronina, S. G., Barrow, S. L., Woodsmith, J. D., Gerasimenko, O. V., . . . Tepikin, A. V. (2007). Activation of trypsinogen in large endocytic vacuoles of pancreatic acinar cells. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 104(13), 5674-5679. doi:10.1073/pnas.0700951104

    DOI: 10.1073/pnas.0700951104

    Magnetic microspheres encoded with photoluminescent quantum dots for multiplexed detection (Journal article)

    Wilson, R., Spiller, D. G., Prior, I. A., Bhatt, R., & Hutchinson, A. (2007). Magnetic microspheres encoded with photoluminescent quantum dots for multiplexed detection. JOURNAL OF MATERIALS CHEMISTRY, 17(41), 4400-4406. doi:10.1039/b708174j

    DOI: 10.1039/b708174j

    Ras proteins: paradigms for compartmentalised and isoform-specific signalling (Journal article)

    Omerovic, J., Laude, A. J., & Prior, I. A. (2007). Ras proteins: paradigms for compartmentalised and isoform-specific signalling. CELLULAR AND MOLECULAR LIFE SCIENCES, 64(19-20), 2575-2589. doi:10.1007/s00018-007-7133-8

    DOI: 10.1007/s00018-007-7133-8

    The Vpu-regulated endocytosis of HIV-1 Gag is clathrin-independent (Journal article)

    Harila, K., Salminen, A., Prior, I., Hinkula, J., & Suomalainen, M. (2007). The Vpu-regulated endocytosis of HIV-1 Gag is clathrin-independent. VIROLOGY, 369(2), 299-308. doi:10.1016/j.virol.2007.08.009

    DOI: 10.1016/j.virol.2007.08.009

    2006

    Control of growth factor receptor dynamics by reversible ubiquitination (Journal article)

    Urbe, S., McCullough, J., Row, P. E., Prior, I. A., Welchman, R., & Clague, M. J. (2006). Control of growth factor receptor dynamics by reversible ubiquitination. BIOCHEMICAL SOCIETY TRANSACTIONS, 34, 754-756. doi:10.1042/BST0340754

    DOI: 10.1042/BST0340754

    The ubiquitin isopeptidase UBPY regulates endosomal ubiquitin dynamics and is essential for receptor down-regulation (Journal article)

    Row, P. E., Prior, I. A., McCullough, J., Clague, M. J., & Urbe, S. (2006). The ubiquitin isopeptidase UBPY regulates endosomal ubiquitin dynamics and is essential for receptor down-regulation. JOURNAL OF BIOLOGICAL CHEMISTRY, 281(18), 12618-12624. doi:10.1074/jbc.M512615200

    DOI: 10.1074/jbc.M512615200

    Vpu and Tsg101 regulate intracellular targeting of the human immunodeficiency virus type 1 core protein precursor Pr55(gag) (Journal article)

    Harila, K., Prior, I., Sjoberg, M., Salminen, A., Hinkula, J., & Suomalainen, M. (2006). Vpu and Tsg101 regulate intracellular targeting of the human immunodeficiency virus type 1 core protein precursor Pr55(gag). JOURNAL OF VIROLOGY, 80(8), 3765-3772. doi:10.1128/JVI.80.8.3765-3772.2006

    DOI: 10.1128/JVI.80.8.3765-3772.2006

    2005

    Electron microscopic imaging of Ras signaling domains (Journal article)

    Hancock, J. F., & Prior, I. A. (2005). Electron microscopic imaging of Ras signaling domains. METHODS, 37(2), 165-172. doi:10.1016/j.ymeth.2005.05.018

    DOI: 10.1016/j.ymeth.2005.05.018

    Individual palmitoyl residues serve distinct roles in H-ras trafficking, microlocalization, and signaling (Journal article)

    Roy, S., Plowman, S., Rotblat, B., Prior, I. A., Muncke, C., Grainger, S., . . . Hancock, J. F. (2005). Individual palmitoyl residues serve distinct roles in H-ras trafficking, microlocalization, and signaling. MOLECULAR AND CELLULAR BIOLOGY, 25(15), 6722-6733. doi:10.1128/MCB.25.15.6722-6733.2005

    DOI: 10.1128/MCB.25.15.6722-6733.2005

    Traffic of Kv4 K+ channels mediated by KChlP1 is via a novel post-ER vesicular pathway (Journal article)

    Hasdemir, B., Fitzgerald, D. J., Prior, I. A., Tepikin, A. V., & Burgoyne, R. D. (2005). Traffic of Kv4 K+ channels mediated by KChlP1 is via a novel post-ER vesicular pathway. JOURNAL OF CELL BIOLOGY, 171(3), 459-469. doi:10.1083/jcb.200506005

    DOI: 10.1083/jcb.200506005

    2004

    Plasma membrane microdomains: organization, function and trafficking (Review) (Journal article)

    Laude, A. J., & Prior, I. A. (2004). Plasma membrane microdomains: organization, function and trafficking (Review). MOLECULAR MEMBRANE BIOLOGY, 21(3), 193-205. doi:10.1080/09687680410001700517

    DOI: 10.1080/09687680410001700517

    Three separable domains regulate GTP-dependent association of H-ras with the plasma membrane (Journal article)

    Rotblat, B., Prior, I. A., Muncke, C., Parton, R. G., Kloog, Y., Henis, Y. I., & Hancock, J. F. (2004). Three separable domains regulate GTP-dependent association of H-ras with the plasma membrane. MOLECULAR AND CELLULAR BIOLOGY, 24(15), 6799-6810. doi:10.1128/MCB.24.15.6799-6810.2004

    DOI: 10.1128/MCB.24.15.6799-6810.2004

    2003

    C-terminal sequences in R-Ras are involved in integrin regulation and in plasma membrane microdomain distribution (Journal article)

    Hansen, M., Prior, I. A., Hughes, P. E., Oertli, B., Chou, F. L., Willumsen, B. M., . . . Ginsberg, M. H. (2003). C-terminal sequences in R-Ras are involved in integrin regulation and in plasma membrane microdomain distribution. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 311(4), 829-838. doi:10.1016/j.bbrc.2003.10.074

    DOI: 10.1016/j.bbrc.2003.10.074

    Caveolin interacts with the angiotensin II type 1 receptor during exocytic transport but not at the plasma membrane (Journal article)

    Wyse, B. D., Prior, I. A., Qian, H. W., Morrow, I. C., Nixon, S., Muncke, C., . . . Hancock, J. F. (2003). Caveolin interacts with the angiotensin II type 1 receptor during exocytic transport but not at the plasma membrane. JOURNAL OF BIOLOGICAL CHEMISTRY, 278(26), 23738-23746. doi:10.1074/jbc.M212892200

    DOI: 10.1074/jbc.M212892200

    Direct visualization of Ras proteins in spatially distinct cell surface microdomains (Journal article)

    Prior, I. A., Muncke, C., Parton, R. G., & Hancock, J. F. (2003). Direct visualization of Ras proteins in spatially distinct cell surface microdomains. JOURNAL OF CELL BIOLOGY, 160(2), 165-170. doi:10.1083/jcb.200209091

    DOI: 10.1083/jcb.200209091

    Observing cell surface signaling domains using electron microscopy. (Journal article)

    Prior, I. A., Parton, R. G., & Hancock, J. F. (2003). Observing cell surface signaling domains using electron microscopy.. Science's STKE : signal transduction knowledge environment, 2003(177), PL9. doi:10.1126/stke.2003.177.pl9

    DOI: 10.1126/stke.2003.177.pl9

    2002

    Flotillin-1/Reggie-2 traffics to surface raft domains via a novel Golgi-independent pathway - Identification of a novel membrane targeting domain and a role for palmitoylation (Journal article)

    Morrow, I. C., Rea, S., Martin, S., Prior, I. A., Prohaska, R., Hancock, J. F., . . . Parton, R. G. (2002). Flotillin-1/Reggie-2 traffics to surface raft domains via a novel Golgi-independent pathway - Identification of a novel membrane targeting domain and a role for palmitoylation. JOURNAL OF BIOLOGICAL CHEMISTRY, 277(50), 48834-48841. doi:10.1074/jbc.M209082200

    DOI: 10.1074/jbc.M209082200

    Inhibition of lipid raft-dependent signaling by a dystrophy-associated mutant of caveolin-3 (Journal article)

    Carozzi, A. J., Roy, S., Morrow, I. C., Pol, A., Wyse, B., Clyde-Smith, J., . . . Parton, R. G. (2002). Inhibition of lipid raft-dependent signaling by a dystrophy-associated mutant of caveolin-3. JOURNAL OF BIOLOGICAL CHEMISTRY, 277(20), 17944-17949. doi:10.1074/jbc.M110879200

    DOI: 10.1074/jbc.M110879200

    2001

    Compartmentalization of Ras proteins. (Journal article)

    Prior, I. A., & Hancock, J. F. (2001). Compartmentalization of Ras proteins.. Journal of cell science, 114(Pt 9), 1603-1608.

    Compartmentalization of Ras proteins (Journal article)

    Prior, I. A., & Hancock, J. F. (2001). Compartmentalization of Ras proteins. JOURNAL OF CELL SCIENCE, 114(9), 1603-1608. Retrieved from http://gateway.webofknowledge.com/

    Compartmentalization of Ras proteins (Journal article)

    Prior, I. A., & Hancock, J. F. (2001). Compartmentalization of Ras proteins. J Cell Sci, 114(Pt 9), 1603-1608. Retrieved from http://www.ncbi.nlm.nih.gov/

    GTP-dependent segregation of H-ras from lipid rafts is required for biological activity (Journal article)

    Prior, I. A., Harding, A., Yan, J., Sluimer, J., Parton, R. G., & Hancock, J. F. (2001). GTP-dependent segregation of H-ras from lipid rafts is required for biological activity. NATURE CELL BIOLOGY, 3(4), 368-375. doi:10.1038/35070050

    DOI: 10.1038/35070050

    Which Ras rides the raft? Reply (Journal article)

    Prior, I. A., Parton, R. G., & Hancock, J. F. (2001). Which Ras rides the raft? Reply. NATURE CELL BIOLOGY, 3(8), E172. doi:10.1038/35087100

    DOI: 10.1038/35087100

    2000

    Detection of thiol modification following generation of reactive nitrogen species: analysis of synaptic vesicle proteins (Journal article)

    Prior, I. A., & Clague, M. J. (2000). Detection of thiol modification following generation of reactive nitrogen species: analysis of synaptic vesicle proteins. BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS, 1475(3), 281-286. doi:10.1016/S0304-4165(00)00078-7

    DOI: 10.1016/S0304-4165(00)00078-7

    H-ras but not K-ras traffics to the plasma membrane through the exocytic pathway (Journal article)

    Apolloni, A., Prior, I. A., Lindsay, M., Parton, R. G., & Hancock, J. F. (2000). H-ras but not K-ras traffics to the plasma membrane through the exocytic pathway. MOLECULAR AND CELLULAR BIOLOGY, 20(7), 2475-2487. doi:10.1128/MCB.20.7.2475-2487.2000

    DOI: 10.1128/MCB.20.7.2475-2487.2000

    1999

    Localization of a class II phosphatidylinositol 3-kinase, PI3KC2alpha, to clathrin-coated vesicles. (Journal article)

    Prior, I. A., & Clague, M. J. (1999). Localization of a class II phosphatidylinositol 3-kinase, PI3KC2alpha, to clathrin-coated vesicles.. Molecular cell biology research communications : MCBRC, 1(2), 162-166. doi:10.1006/mcbr.1999.0126

    DOI: 10.1006/mcbr.1999.0126

    1998

    Evaluation of X-ray microfluorescence spectrometry for the elemental analysis of firearm discharge residues (Journal article)

    Flynn, J., Stoilovic, M., Lennard, C., Prior, L., & Kobus, H. (1998). Evaluation of X-ray microfluorescence spectrometry for the elemental analysis of firearm discharge residues. FORENSIC SCIENCE INTERNATIONAL, 97(1), 21-36. doi:10.1016/S0379-0738(98)00127-3

    DOI: 10.1016/S0379-0738(98)00127-3

    1997

    Glutamate uptake occurs at an early stage of synaptic vesicle recycling (Journal article)

    Prior, I. A., & Clague, M. J. (1997). Glutamate uptake occurs at an early stage of synaptic vesicle recycling. CURRENT BIOLOGY, 7(5), 353-356. doi:10.1016/S0960-9822(06)00159-X

    DOI: 10.1016/S0960-9822(06)00159-X