Publications
2024
Near millimolar concentration of nucleosomes in mitotic chromosomes from late prometaphase into anaphase.
Cisneros-Soberanis, F., Simpson, E. L., Beckett, A. J., Pucekova, N., Corless, S., Kochanova, N. Y., . . . Earnshaw, W. C. (2024). Near millimolar concentration of nucleosomes in mitotic chromosomes from late prometaphase into anaphase.. The Journal of cell biology, 223(11), e202403165. doi:10.1083/jcb.202403165
Rules of engagement for condensins and cohesins guide mitotic chromosome formation.
2023
Ras protein abundance correlates with Ras isoform mutation patterns in cancer
Hood, F. E., Sahraoui, Y. M., Jenkins, R. E., & Prior, I. A. (2023). Ras protein abundance correlates with Ras isoform mutation patterns in cancer. ONCOGENE, 42(15), 1224-1232. doi:10.1038/s41388-023-02638-1
2022
Combinatorial approaches for mitigating resistance to KRAS-targeted therapies
Warren, H. R., Ross, S. J., Smith, P. D., Coulson, J. M., & Prior, I. A. (2022). Combinatorial approaches for mitigating resistance to KRAS-targeted therapies. BIOCHEMICAL JOURNAL, 479(18), 1985-1997. doi:10.1042/BCJ20220440
The importance of Ras in drug resistance in cancer
Healy, F. M., Prior, I. A., & MacEwan, D. J. (2022). The importance of Ras in drug resistance in cancer. BRITISH JOURNAL OF PHARMACOLOGY, 179(12), 2844-2867. doi:10.1111/bph.15420
Novel roles of RTN4 and CLIMP-63 in regulating mitochondrial structure, bioenergetics and apoptosis
Carter, R. J., Milani, M., Beckett, A. J., Liu, S., Prior, I. A., Cohen, G. M., & Varadarajan, S. (2022). Novel roles of RTN4 and CLIMP-63 in regulating mitochondrial structure, bioenergetics and apoptosis. CELL DEATH & DISEASE, 13(5). doi:10.1038/s41419-022-04869-8
Effect of Local Topography on Cell Division of <i>Staphylococcus</i> spp.
Sorzabal-Bellido, I., Barbieri, L., Beckett, A. J., Prior, I. A., Susarrey-Arce, A., Tiggelaar, R. M., . . . Fernandez, Y. A. D. (2022). Effect of Local Topography on Cell Division of <i>Staphylococcus</i> spp.. NANOMATERIALS, 12(4). doi:10.3390/nano12040683
2021
Kinobead Profiling Reveals Reprogramming of BCR Signaling in Response to Therapy within Primary CLL Cells
Linley, A. J., Karydis, L. I., Mondru, A. K., D'Avola, A., Al Shmrany, H., Cicconi, S., . . . Slupsky, J. R. (2021). Kinobead Profiling Reveals Reprogramming of BCR Signaling in Response to Therapy within Primary CLL Cells. CLINICAL CANCER RESEARCH, 27(20), 5647-5659. doi:10.1158/1078-0432.CCR-21-0161
Carcinogen-induced DNA structural distortion differences in the <i>RAS</i> gene isoforms; the importance of local sequence
Menzies, G. E., Prior, I. A., Brancale, A., Reed, S. H., & Lewis, P. D. (2021). Carcinogen-induced DNA structural distortion differences in the <i>RAS</i> gene isoforms; the importance of local sequence. BMC CHEMISTRY, 15(1). doi:10.1186/s13065-021-00777-8
One-step preparation of antimicrobial silicone materials based on PDMS and salicylic acid: insights from spatially and temporally resolved techniques
Barbieri, L., Sorzabal Bellido, I., Beckett, A. J., Prior, I. A., Fothergill, J., Diaz Fernandez, Y. A., & Raval, R. (2021). One-step preparation of antimicrobial silicone materials based on PDMS and salicylic acid: insights from spatially and temporally resolved techniques. NPJ BIOFILMS AND MICROBIOMES, 7(1). doi:10.1038/s41522-021-00223-6
Tumour Initiation: Danger zone
Butt, Z., & Prior, I. (2021). Tumour Initiation: Danger zone. ELIFE, 10. doi:10.7554/eLife.69192
Absolute Quantitation of GTPase Protein Abundance
Hood, F. E., Sahraoui, Y. M., Jenkins, R. E., & Prior, I. (2021). Absolute Quantitation of GTPase Protein Abundance. RAS ACTIVITY AND SIGNALING, 2262, 65-90. doi:10.1007/978-1-0716-1190-6_4
Ras Variant Biology and Contributions to Human Disease.
Prior, I. (2021). Ras Variant Biology and Contributions to Human Disease.. Methods in molecular biology (Clifton, N.J.), 2262, 3-18. doi:10.1007/978-1-0716-1190-6_1
2020
Structural insights into loss of function of a pore forming toxin and its role in pneumococcal adaptation to an intracellular lifestyle
Badgujar, D. C., Anil, A., Green, A. E., Surve, M. V., Madhavan, S., Beckett, A., . . . Banerjee, A. (2020). Structural insights into loss of function of a pore forming toxin and its role in pneumococcal adaptation to an intracellular lifestyle. PLOS PATHOGENS, 16(11). doi:10.1371/journal.ppat.1009016
Exploring High Aspect Ratio Gold Nanotubes as Cytosolic Agents: Structural Engineering and Uptake into Mesothelioma Cells
Ye, S., Azad, A. A., Chambers, J. E., Beckett, A. J., Roach, L., Moorcroft, S. C. T., . . . Evans, S. D. (2020). Exploring High Aspect Ratio Gold Nanotubes as Cytosolic Agents: Structural Engineering and Uptake into Mesothelioma Cells. Small, 2003793. doi:10.1002/smll.202003793
The Frequency of Ras Mutations in Cancer
Prior, I. A., Hood, F. E., & Hartley, J. L. (2020). The Frequency of Ras Mutations in Cancer. Cancer Research, 80(14), 2969-2974. doi:10.1158/0008-5472.CAN-19-3682
LAP-like non-canonical autophagy and evolution of endocytic vacuoles in pancreatic acinar cells
De Faveri, F., Chvanov, M., Voronina, S., Moore, D., Pollock, L., Haynes, L., . . . Tepikin, A. (2020). LAP-like non-canonical autophagy and evolution of endocytic vacuoles in pancreatic acinar cells. Autophagy, 16(7), 1314-1331. doi:10.1080/15548627.2019.1679514
Trypanosoma brucei colonizes the tsetse gut via an immature peritrophic matrix in the proventriculus
Rose, C., Casas-Sanchez, A., Dyer, N. A., Solorzano, C., Beckett, A. J., Middlehurst, B., . . . Acosta-Serrano, A. (2020). Trypanosoma brucei colonizes the tsetse gut via an immature peritrophic matrix in the proventriculus. Nature Microbiology, 5(7), 909-916. doi:10.1038/s41564-020-0707-z
Structural insights into loss of function of a pore forming toxin and its role in pneumococcal adaptation to an intracellular lifestyle
Badgujar, D., Anil, A., Green, A., Surve, M. V., Madhavan, S., Beckett, A., . . . Banerjee, A. (2020). Structural insights into loss of function of a pore forming toxin and its role in pneumococcal adaptation to an intracellular lifestyle. doi:10.1101/2020.05.13.093682
Abstract A11: Screening the Ras proteome microenvironment using APEX2
Mo, S. P., Coulson, J. M., & Prior, I. A. (2020). Abstract A11: Screening the Ras proteome microenvironment using APEX2. Molecular Cancer Research, 18(5_Supplement), A11. doi:10.1158/1557-3125.ras18-a11
Screening the Ras proteome microenvironment using APEX2.
Mo, S. P., Coulson, J. M., & Prior, I. A. (2020). Screening the Ras proteome microenvironment using APEX2.. In MOLECULAR CANCER RESEARCH Vol. 18 (pp. 38). Retrieved from https://www.webofscience.com/
2019
ER stress-linked autophagy stabilizes apoptosis effector PERP and triggers its co-localization with SERCA2b at ER-plasma membrane junctions
McDonnell, S. J., Spiller, D. G., White, M. R. H., Prior, I. A., & Paraoan, L. (2019). ER stress-linked autophagy stabilizes apoptosis effector PERP and triggers its co-localization with SERCA2b at ER-plasma membrane junctions. CELL DEATH DISCOVERY, 5. doi:10.1038/s41420-019-0212-4
Kinobead Profiling Reveals Reprogramming of B-cell Receptor Signaling in Response to Therapy Within Primary Chronic Lymphocytic Leukemia Cells
Targeting centrosome amplification, an Achilles' heel of cancer
Sabat-Pospiech, D., Fabian-Kolpanowicz, K., Prior, I. A., Coulson, J. M., & Fielding, A. B. (2019). Targeting centrosome amplification, an Achilles' heel of cancer. BIOCHEMICAL SOCIETY TRANSACTIONS, 47, 1209-1222. doi:10.1042/BST20190034
Exploiting Covalent, H-Bonding, and π–π Interactions to Design Antibacterial PDMS Interfaces That Load and Release Salicylic Acid
Sorzabal Bellido, I., Diaz Fernandez, Y. A., Skelton, A. A., Susarrey Arce, A., McBride, F., Prior, I. A., . . . Raval, R. (2019). Exploiting Covalent, H-Bonding, and π–π Interactions to Design Antibacterial PDMS Interfaces That Load and Release Salicylic Acid. ACS Appl. Bio Mater.. doi:10.1021/acsabm.9b00562
ER stress-linked autophagy stabilizes apoptosis effector PERP and triggers its co-localization with SERCA2b at ER-plasma membrane junctions
McDonnell, S., Spiller, D., White, M., Prior, I., & Paraoan, L. (2019). ER stress-linked autophagy stabilizes apoptosis effector PERP and triggers its co-localization with SERCA2b at ER-plasma membrane junctions. doi:10.1101/742882
Concentric lamellae - novel microanatomical structures in the articular calcified cartilage of mice
Keenan, C. M., Beckett, A. J., Sutherland, H., Ranganath, L. R., Jarvis, J. C., Prior, I. A., & Gallagher, J. A. (2019). Concentric lamellae - novel microanatomical structures in the articular calcified cartilage of mice. SCIENTIFIC REPORTS, 9. doi:10.1038/s41598-019-47545-2
Integrin αVβ6-EGFR crosstalk regulates bidirectional force transmission and controls breast cancer invasion
Thomas, J. R., Moore, K. M., Sproat, C., Mo, S., Wolanska, K. I., Maldonado, H., . . . Morgan, M. (2019). Integrin αVβ6-EGFR crosstalk regulates bidirectional force transmission and controls breast cancer invasion. In INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY Vol. 100 (pp. A39). doi:10.1111/iep.12332
DRP-1 functions independently of mitochondrial structural perturbations to facilitate BH3 mimetic-mediated apoptosis.
Milani, M., Beckett, A. J., Al-Zebeeby, A., Luo, X., Prior, I. A., Cohen, G. M., & Varadarajan, S. (2019). DRP-1 functions independently of mitochondrial structural perturbations to facilitate BH3 mimetic-mediated apoptosis.. Cell death discovery, 5, 117. doi:10.1038/s41420-019-0199-x
Endocytic vacuoles in pancreatic acinar cells: actination, dynamics, rupture and exocytosis.
Voronina, S., De Faveri, F., Chvanov, M., Moore, D., Sherwood, M., Awais, M., . . . Tepikin, A. (2019). Endocytic vacuoles in pancreatic acinar cells: actination, dynamics, rupture and exocytosis.. Pancreatology, 19, S17. doi:10.1016/j.pan.2019.05.036
PF370 SIGNAL-OMICS ANALYSIS OF THE IMPACT OF THERAPY ON BCR SIGNALLING IN CHRONIC LYMPHOCYTIC LEUKAEMIA
Linley, A., Kalakonda, N., MacEwan, D., Prior, I., & Slupsky, J. (2019). PF370 SIGNAL-OMICS ANALYSIS OF THE IMPACT OF THERAPY ON BCR SIGNALLING IN CHRONIC LYMPHOCYTIC LEUKAEMIA. HemaSphere, 3(S1), 136-137. doi:10.1097/01.hs9.0000559692.06651.82
SuperCLEM: an accessible correlative light and electron microscopy approach for investigation of neurons and glia in vitro.
Booth, D. G., Beckett, A. J., Prior, I. A., & Meijer, D. (2019). SuperCLEM: an accessible correlative light and electron microscopy approach for investigation of neurons and glia in vitro.. Biology open. doi:10.1242/bio.042085
Isoform-specific Ras signaling is growth factor dependent
Hood, F. E., Klinger, B., Newlaczyl, A. U., Sieber, A., Dorel, M., Oliver, S. P., . . . Prior, I. A. (2019). Isoform-specific Ras signaling is growth factor dependent. Molecular biology of the cell, 30(9), 1108-1117. doi:10.1091/mbc.e18-10-0676
Trypanosoma brucei colonises the tsetse gut via an immature peritrophic matrix in the proventriculus
Rose, C., Dyer, N., Casas-Sanchez, A., Beckett, A., Solórzano, C., Middlehurst, B., . . . Acosta-Serrano, Á. (2019). <i>Trypanosoma brucei</i>colonises the tsetse gut via an immature peritrophic matrix in the proventriculus. doi:10.1101/513689
2018
Fibroblast Growth Factor 2 lethally sensitizes cancer cells to stress-targeted therapeutic inhibitors.
Dias, M. H., Fonseca, C. S., Zeidler, J. D., Albuquerque, L. L., da Silva, M. S., Lopes-Cararo, E., . . . Armelin, H. A. (2018). Fibroblast Growth Factor 2 lethally sensitizes cancer cells to stress-targeted therapeutic inhibitors.. Molecular oncology. doi:10.1002/1878-0261.12402
RAS variant signalling
Mo, S. P., Coulson, J. M., & Prior, I. A. (2018). RAS variant signalling. BIOCHEMICAL SOCIETY TRANSACTIONS, 46, 1325-1332. doi:10.1042/BST20180173
Eps8 is a convergence point integrating EGFR and integrin trafficking and crosstalk
Paul, N., Thomas, J., Maldonado, H., Wolanska, K., Koper, E., Humphries, J., . . . Morgan, M. (2018). Eps8 is a convergence point integrating EGFR and integrin trafficking and crosstalk. doi:10.1101/405043
Integrin αVβ6-EGFR crosstalk regulates bidirectional force transmission and controls breast cancer invasion
Thomas, J. R., Moore, K. M., Sproat, C., Mo, S., Wolanska, K. I., Maldonado, H., . . . Morgan, M. R. (2019). Integrin αVβ6-EGFR crosstalk regulates bidirectional force transmission and controls breast cancer invasion. INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY, 100(4), A39. Retrieved from https://www.webofscience.com/
Integrin αVβ6-EGFR crosstalk regulates bidirectional force transmission and controls breast cancer invasion
Thomas, J., Moore, K., Sproat, C., Maldonado-Lorca, H., Mo, S., Haider, S., . . . Morgan, M. (2018). Integrin αVβ6-EGFR crosstalk regulates bidirectional force transmission and controls breast cancer invasion. doi:10.1101/407908
Long-Chain n-3 Fatty Acids Attenuate Oncogenic KRas-Driven Proliferation by Altering Plasma Membrane Nanoscale Proteolipid Composition
Fuentes, N. R., Mlih, M., Barhoumi, R., Fan, Y. -Y., Hardin, P., Steele, T. J., . . . Chapkin, R. S. (2018). Long-Chain n-3 Fatty Acids Attenuate Oncogenic KRas-Driven Proliferation by Altering Plasma Membrane Nanoscale Proteolipid Composition. CANCER RESEARCH, 78(14), 3899-3912. doi:10.1158/0008-5472.CAN-18-0324
The deubiquitylase USP15 regulates topoisomerase II alpha to maintain genome integrity
Fielding, A. B., Concannon, M., Darling, S., Rusilowicz, E., Sacco, J., Prior, I. A., . . . Coulson, J. M. (2018). The deubiquitylase USP15 regulates topoisomerase II alpha to maintain genome integrity. Oncogene, 37(17), 2326-2342. doi:10.1038/s41388-017-0092-0
New Perspectives, Opportunities, and Challenges in Exploring the Human Protein Kinome
Wilson, L. J., Linley, A., Hammond, D. E., Hood, F. E., Coulson, J. M., MacEwan, D. J., . . . Prior, I. A. (2018). New Perspectives, Opportunities, and Challenges in Exploring the Human Protein Kinome. CANCER RESEARCH, 78(1), 15-29. doi:10.1158/0008-5472.CAN-17-2291
2017
Fibroblast Growth Factor 2 lethally sensitizes cancer cells to stress-targeted therapeutic inhibitors
Regulation of the cell cycle and centrosome biology by deubiquitylases
Darling, S., Fielding, A. B., Sabat-Pospiech, D., Prior, I. A., & Coulson, J. M. (2017). Regulation of the cell cycle and centrosome biology by deubiquitylases. BIOCHEMICAL SOCIETY TRANSACTIONS, 45, 1125-1136. doi:10.1042/BST20170087
Modulating Protein-Protein Interactions of the Mitotic Polo-like Kinases to Target Mutant KRAS
Narvaez, A. J., Ber, S., Crooks, A., Emery, A., Hardwick, B., Almeida, E. G., . . . Venkitaraman, A. R. (2017). Modulating Protein-Protein Interactions of the Mitotic Polo-like Kinases to Target Mutant KRAS. CELL CHEMICAL BIOLOGY, 24(8), 1017-1028.E7. doi:10.1016/j.chembiol.2017.07.009
Modular approach for bimodal antibacterial surfaces combining photo-switchable activity and sustained biocidal release
Pallavicini, P., Bassi, B., Chirico, G., Collini, M., Dacarro, G., Fratini, E., . . . Diaz Fernandez, Y. A. (2017). Modular approach for bimodal antibacterial surfaces combining photo-switchable activity and sustained biocidal release. Scientific Reports, 7. doi:10.1038/s41598-017-05693-3
Abstract 179: Plasma membrane lipid therapy: disruption of oncogenic Ras spatiotemporal organization by membrane-targeted dietary bioactives (MTDB)
Fuentes, N. R., Barhoumi, R., Mlih, M., Karpac, J., Hardin, P., Steele, T., . . . Chapkin, R. S. (2017). Abstract 179: Plasma membrane lipid therapy: disruption of oncogenic Ras spatiotemporal organization by membrane-targeted dietary bioactives (MTDB). Cancer Research, 77(13_Supplement), 179. doi:10.1158/1538-7445.am2017-179
Serial block-face scanning electron microscopy applied to study the trafficking of 8D3-coated gold nanoparticles at the blood-brain barrier
Cabezón, I., Augé, E., Bosch, M., Beckett, A. J., Prior, I. A., Pelegrí, C., & Vilaplana, J. (2017). Serial block-face scanning electron microscopy applied to study the trafficking of 8D3-coated gold nanoparticles at the blood-brain barrier. Histochemistry and cell biology, 148(01), 3-12. doi:10.1007/s00418-017-1553-9
Microtubule organization within mitotic spindles revealed by serial block face scanning electron microscopy and image analysis
Nixon, F. M., Honnor, T. R., Clarke, N. I., Starling, G. P., Beckett, A. J., Johansen, A. M., . . . Royle, S. J. (2017). Microtubule organization within mitotic spindles revealed by serial block face scanning electron microscopy and image analysis. Journal of Cell Science, 130(10), 1845-1855. doi:10.1242/jcs.203877
Conserved effects and altered trafficking of Cetuximab antibodies conjugated to gold nanoparticles with precise control of their number and orientation
García-Fernández, L., Garcia-Pardo, J., Tort, O., Prior, I., Brust, M., Casals, E., . . . Puntes, V. F. (2017). Conserved effects and altered trafficking of Cetuximab antibodies conjugated to gold nanoparticles with precise control of their number and orientation. NANOSCALE, 9(18), 6111-6121. doi:10.1039/c7nr00947j
Exploring the protein-protein interactions of the p53 apoptosis effector protein PERP
McDonnell, S. J., Prior, I., & Paraoan, L. I. (2017). Exploring the protein-protein interactions of the p53 apoptosis effector protein PERP. In INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE Vol. 58. Retrieved from https://www.webofscience.com/
Quantification of spatiotemporal patterns of Ras isoform expression during development
Newlaczyl, A. U., Coulson, J. M., & Prior, I. A. (2017). Quantification of spatiotemporal patterns of Ras isoform expression during development. Scientific reports, 7. doi:10.1038/srep41297
2016
The endoplasmic reticulum remains functionally connected by vesicular transport after its fragmentation in cells expressing Z‐α1‐antitrypsin
Dickens, J. A., Ordóñez, A., Chambers, J. E., Beckett, A. J., Patel, V., Malzer, E., . . . Marciniak, S. J. (2016). The endoplasmic reticulum remains functionally connected by vesicular transport after its fragmentation in cells expressing Z‐α1‐antitrypsin. The FASEB Journal, 30(12), 4083-4097. doi:10.1096/fj.201600430R
3D-CLEM Reveals that a Major Portion of Mitotic Chromosomes Is Not Chromatin
Booth, D. G., Beckett, A. J., Molina, O., Samejima, I., Masumoto, H., Kouprina, N., . . . Earnshaw, W. C. (2016). 3D-CLEM Reveals that a Major Portion of Mitotic Chromosomes Is Not Chromatin. Molecular cell, 64(4), 790-802. doi:10.1016/j.molcel.2016.10.009
Microtubule organization within mitotic spindles revealed by serial block face scanning EM and image analysis
Feedback activation of neurofibromin terminates growth factor-induced Ras activation
Hennig, A., Markwart, R., Wolff, K., Schubert, K., Cui, Y., Prior, I. A., . . . Rubio, I. (2016). Feedback activation of neurofibromin terminates growth factor-induced Ras activation. CELL COMMUNICATION AND SIGNALING, 14, 14 pages. doi:10.1186/s12964-016-0128-z
2015
Comparative proteomic analysis of compartmentalised Ras signalling
Hernandez-Valladares, M., & Prior, I. A. (2015). Comparative proteomic analysis of compartmentalised Ras signalling. SCIENTIFIC REPORTS, 5. doi:10.1038/srep17307
Absolute Quantification of Endogenous Ras Isoform Abundance
Mageean, C. J., Griffiths, J. R., Smith, D. L., Clague, M. J., & Prior, I. A. (2015). Absolute Quantification of Endogenous Ras Isoform Abundance. PLOS ONE, 10(11). doi:10.1371/journal.pone.0142674
The mesh is a network of microtubule connectors that stabilizes individual kinetochore fibers of the mitotic spindle
Nixon, F. M., Gutierrez-Caballero, C., Hood, F. E., Booth, D. G., Prior, I. A., & Royle, S. J. (2015). The mesh is a network of microtubule connectors that stabilizes individual kinetochore fibers of the mitotic spindle. ELIFE, 4. doi:10.7554/eLife.07635
The role of Ca2+influx in endocytic vacuole formation in pancreatic acinar cells
Voronina, S., Collier, D., Chvanov, M., Middlehurst, B., Beckett, A., Prior, I., . . . Tepikin, A. V. (2015). The role of Ca2+influx in endocytic vacuole formation in pancreatic acinar cells. Biochemical Journal, 465(3), 405-412. doi:10.1042/BJ20140398
Differential Reprogramming of Isogenic Colorectal Cancer Cells by Distinct Activating KRAS Mutations
Hammond, D., Mageean, C., Rusilowicz, E., Wickenden, J. A., Clague, M., & Prior, I. (2015). Differential Reprogramming of Isogenic Colorectal Cancer Cells by Distinct Activating KRAS Mutations. Journal of Proteome Research, 14(3), 1535-1546. doi:10.1021/pr501191a
Electron Microscopy Methods for Studying Plasma Membranes
Beckett, A. J., & Prior, I. A. (2015). Electron Microscopy Methods for Studying Plasma Membranes. METHODS IN MEMBRANE LIPIDS, SECOND EDITION, 1232, 137-151. doi:10.1007/978-1-4939-1752-5_12
2014
Differential network reprogramming by distinct activating K-Ras mutations
Hammond, D. E., Mageean, C. J., Rusilowicz, E. V., Clague, M. J., & Prior, I. A. (2014). Differential network reprogramming by distinct activating K-Ras mutations. In MOLECULAR CANCER RESEARCH Vol. 12. doi:10.1158/1557-3125.RASONC14-B30
Tissue- and isoform-specific Ras expression during development
Newlaczyl, A. U., Coulson, J. M., & Prior, I. A. (2014). Tissue- and isoform-specific Ras expression during development. In CANCER RESEARCH Vol. 74. doi:10.1158/1538-7445.AM2014-4449
Plasticity of Mammary Cell Boundaries Governed by EGF and Actin Remodeling
Tang, W. Y., Beckett, A., Prior, I., Coulson, J., Urbe, S., & Clague, M. (2014). Plasticity of Mammary Cell Boundaries Governed by EGF and Actin Remodeling. Cell Reports, 8(06), 1722-1730. doi:10.1016/j.celrep.2014.08.026
Molecular dynamics modelling of local 3D structural differences in genes when carcinogens are bound at mutation hotspots – The link between structural change and mutation hotspot status
Menzies, G., Brancale, A., Prior, I., & Lewis, P. (2014). Molecular dynamics modelling of local 3D structural differences in genes when carcinogens are bound at mutation hotspots – The link between structural change and mutation hotspot status. Toxicology Letters, 229, S163. doi:10.1016/j.toxlet.2014.06.560
Decoding RAS isoform and codon-specific signalling
Newlaczyl, A. U., Hood, F. E., Coulson, J. M., & Prior, I. A. (2014). Decoding RAS isoform and codon-specific signalling. BIOCHEMICAL SOCIETY TRANSACTIONS, 42, 742-746. doi:10.1042/BST20140057
The neuroendocrine phenotype of gastric myofibroblasts and its loss with cancer progression
Balabanova, S., Holmberg, C., Steele, I., Ebrahimi, B., Rainbow, L., Burdyga, T., . . . Varro, A. (2014). The neuroendocrine phenotype of gastric myofibroblasts and its loss with cancer progression. Carcinogenesis, 35(8), 1798-1806. doi:10.1093/carcin/bgu086
The neuroendocrine phenotype of gastric myofibroblasts and its loss with cancer progression
Balabanova, S., Holmberg, C., Steele, I., Ebrahimi, B., Rainbow, L., Burdyga, T., . . . Varro, A. (2014). The neuroendocrine phenotype of gastric myofibroblasts and its loss with cancer progression. Carcinogenesis, 35(8), 1798-1806. doi:10.1093/carcin/bgu086
IDENTIFICATION OF CONCENTRIC LAMELLAE IN THE ARTICULAR CALCIFIED CARTILAGE OF OSTEOARTHRITIC MICE
Keenan, C. M., Beckett, A., Sutherland, H., Prior, I., Ranganath, L. R., Jarvis, J. C., & Gallagher, J. A. (2014). IDENTIFICATION OF CONCENTRIC LAMELLAE IN THE ARTICULAR CALCIFIED CARTILAGE OF OSTEOARTHRITIC MICE. In OSTEOARTHRITIS AND CARTILAGE Vol. 22 (pp. S363-S364). doi:10.1016/j.joca.2014.02.673
Decoding RAS isoform and codon-specific signalling
Newlaczyl, A. U., Hood, F. E., Coulson, J. M., & Prior, I. A. (2014). Decoding RAS isoform and codon-specific signalling. Biochem. Soc. Trans., 4, 7426.
Quantitative Proteomic Analysis of Compartmentalized Signaling Networks
Hernandez-Valladares, M., Aran, V., & Prior, I. A. (2014). Quantitative Proteomic Analysis of Compartmentalized Signaling Networks. ENDOSOME SIGNALING, PT B, 535, 309-325. doi:10.1016/B978-0-12-397925-4.00018-3
2013
Pronounced in vivo hemoglobin polymerization in red blood cells of Gulf toadfish: a general role for hemoglobin aggregation in vertebrate hemoparasite defense?
Koldkjaer, P., McDonald, M. D., Prior, I., & Berenbrink, M. (2013). Pronounced in vivo hemoglobin polymerization in red blood cells of Gulf toadfish: a general role for hemoglobin aggregation in vertebrate hemoparasite defense?. AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY, 305(10), R1190-R1199. doi:10.1152/ajpregu.00246.2013
Oncogenic K-ras segregates at spatially distinct plasma membrane signaling platforms according to its phosphorylation status
Barcelo, C., Paco, N., Beckett, A. J., Alvarez-Moya, B., Garrido, E., Gelabert, M., . . . Agell, N. (2013). Oncogenic K-ras segregates at spatially distinct plasma membrane signaling platforms according to its phosphorylation status. JOURNAL OF CELL SCIENCE, 126(20), 4553-4559. doi:10.1242/jcs.123737
Ras palmitoylation is necessary for N-Ras activation and signal propagation in growth factor signalling
Song, S. -P., Hennig, A., Schubert, K., Markwart, R., Schmidt, P., Prior, I. A., . . . Rubio, I. (2013). Ras palmitoylation is necessary for N-Ras activation and signal propagation in growth factor signalling. Biochemical Journal, 455(1), 131. doi:10.1042/bj4550131v
Compartmentalized Ras signaling differentially contributes to phenotypic outputs
Aran, V., & Prior, I. A. (2013). Compartmentalized Ras signaling differentially contributes to phenotypic outputs. CELLULAR SIGNALLING, 25(9), 1748-1753. doi:10.1016/j.cellsig.2013.05.004
Ras palmitoylation is necessary for N-Ras activation and signal propagation in growth factor signalling
Song, S. -P., Hennig, A., Schubert, K., Markwart, R., Schmidt, P., Prior, I. A., . . . Rubio, I. (2013). Ras palmitoylation is necessary for N-Ras activation and signal propagation in growth factor signalling. BIOCHEMICAL JOURNAL, 454, 323-332. doi:10.1042/BJ20121799
Specific removal of TACC3-ch-TOG-clathrin at metaphase deregulates kinetochore fiber tension
Cheeseman, L. P., Harry, E. F., McAinsh, A. D., Prior, I. A., & Royle, S. J. (2013). Specific removal of TACC3-ch-TOG-clathrin at metaphase deregulates kinetochore fiber tension. JOURNAL OF CELL SCIENCE, 126(9), 2102-2113. doi:10.1242/jcs.124834
CD317/tetherin is an organiser of membrane microdomains
Billcliff, P. G., Rollason, R., Prior, I., Owen, D. M., Gaus, K., & Banting, G. (2013). CD317/tetherin is an organiser of membrane microdomains. JOURNAL OF CELL SCIENCE, 126(7), 1553-1564. doi:10.1242/jcs.112953
The role of palmitoylation in regulating Ras localization and function
Eisenberg, S., Laude, A. J., Beckett, A. J., Mageean, C. J., Aran, V., Hernandez-Valladares, M., . . . Prior, I. A. (2013). The role of palmitoylation in regulating Ras localization and function. BIOCHEMICAL SOCIETY TRANSACTIONS, 41, 79-83. doi:10.1042/BST20120268
Plasticity of mammary cell boundaries governed by EGF
Tang, Y., Beckett, A. J., Prior, I. A., Coulson, J. M., Urbe, S., & Clague, M. J. (2013). Plasticity of mammary cell boundaries governed by EGF. MOLECULAR BIOLOGY OF THE CELL, 24. Retrieved from https://www.webofscience.com/
Studying Kinetochore-Fiber Ultrastructure Using Correlative Light-Electron Microscopy
Booth, D. G., Cheeseman, L. P., Prior, I. A., & Royle, S. J. (2013). Studying Kinetochore-Fiber Ultrastructure Using Correlative Light-Electron Microscopy. MICROTUBULES, IN VITRO, 2ND EDITION, 115, 327-342. doi:10.1016/B978-0-12-407757-7.00020-7
2012
Global Snapshot of the Influence of Endocytosis upon EGF Receptor Signaling Output
Omerovic, J., Hammond, D. E., Prior, I. A., & Clague, M. J. (2012). Global Snapshot of the Influence of Endocytosis upon EGF Receptor Signaling Output. Journal of Proteome Research, 11(11), 5157-5166. doi:10.1021/pr3007304
Global Snapshot of the Influence of Endocytosis upon EGF Receptor Signaling Output
Omerovic, J., Hammond, D. E., Prior, I. A., & Clague, M. J. (2012). Global Snapshot of the Influence of Endocytosis upon EGF Receptor Signaling Output. JOURNAL OF PROTEOME RESEARCH, 11(11), 5157-5166. doi:10.1021/pr3007304
Transport of Fibroblast Growth Factor 2 in the Pericellular Matrix Is Controlled by the Spatial Distribution of Its Binding Sites in Heparan Sulfate
Duchesne, L., Octeau, V., Bearon, R. N., Beckett, A., Prior, I. A., Lounis, B., & Fernig, D. G. (2012). Transport of Fibroblast Growth Factor 2 in the Pericellular Matrix Is Controlled by the Spatial Distribution of Its Binding Sites in Heparan Sulfate. PLOS BIOLOGY, 10(7). doi:10.1371/journal.pbio.1001361
A Comprehensive Survey of Ras Mutations in Cancer
Prior, I. A., Lewis, P. D., & Mattos, C. (2012). A Comprehensive Survey of Ras Mutations in Cancer. CANCER RESEARCH, 72(10), 2457-2467. doi:10.1158/0008-5472.CAN-11-2612
Mercaptocarborane-Capped Gold Nanoparticles: Electron Pools and Ion Traps with Switchable Hydrophilicity
Cioran, A. M., Musteti, A. D., Teixidor, F., Krpetic, Z., Prior, I. A., He, Q., . . . Vinas, C. (2012). Mercaptocarborane-Capped Gold Nanoparticles: Electron Pools and Ion Traps with Switchable Hydrophilicity. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 134(1), 212-221. doi:10.1021/ja203367h
Putting signalling into context
Prior, I. A. (2012). Putting signalling into context. SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY, 23(2), 125. doi:10.1016/j.semcdb.2012.02.008
Quantitative FRAP Analysis Demonstrates that Raft Protein Clustering Alters N-Ras Depalmitoylation, Membrane Interactions and Activation Pattern
Eisenberg, S., Wolfenson, H., Berkovich, R., Prior, I. A., Ehrlich, M., Klafter, J., . . . Henis, Y. I. (2012). Quantitative FRAP Analysis Demonstrates that Raft Protein Clustering Alters N-Ras Depalmitoylation, Membrane Interactions and Activation Pattern. Biophysical Journal, 102(3), 32a. doi:10.1016/j.bpj.2011.11.201
Ras trafficking, localization and compartmentalized signalling
Prior, I. A., & Hancock, J. F. (2012). Ras trafficking, localization and compartmentalized signalling. SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY, 23(2), 145-153. doi:10.1016/j.semcdb.2011.09.002
2011
Raft Protein Clustering Alters N-Ras Membrane Interactions and Activation Pattern
Eisenberg, S., Beckett, A. J., Prior, I. A., Dekker, F. J., Hedberg, C., Waldmann, H., . . . Henis, Y. I. (2011). Raft Protein Clustering Alters N-Ras Membrane Interactions and Activation Pattern. MOLECULAR AND CELLULAR BIOLOGY, 31(19), 3938-3952. doi:10.1128/MCB.05570-11
Intracellular mapping with SERS-encoded gold nanostars
Rodriguez-Lorenzo, L., Krpetic, Z., Barbosa, S., Alvarez-Puebla, R. A., Liz-Marzan, L. M., Prior, I. A., & Brust, M. (2011). Intracellular mapping with SERS-encoded gold nanostars. INTEGRATIVE BIOLOGY, 3(9), 922-926. doi:10.1039/c1ib00029b
Acrylate-Facilitated Cellular Uptake of Gold Nanoparticles
Krpetic, Z., Nativo, P., Prior, I. A., & Brust, M. (2011). Acrylate-Facilitated Cellular Uptake of Gold Nanoparticles. SMALL, 7(14), 1982-1986. doi:10.1002/smll.201100462
Aurora A kinase activity is required for localization of TACC3/ch-TOG/clathrin inter-microtubule bridges
Cheeseman, L. P., Booth, D. G., Hood, F. E., Prior, I. A., & Royle, S. J. (2011). Aurora A kinase activity is required for localization of TACC3/ch-TOG/clathrin inter-microtubule bridges. Communicative & Integrative Biology, 4(4), 409-412. doi:10.4161/cib.15250
Aurora A kinase activity is required for localization of TACC3/ch-TOG/clathrin inter-microtubule bridges.
Cheeseman, L. P., Booth, D. G., Hood, F. E., Prior, I. A., & Royle, S. J. (2011). Aurora A kinase activity is required for localization of TACC3/ch-TOG/clathrin inter-microtubule bridges.. Communicative & integrative biology, 4(4), 409-412. doi:10.4161/cib.4.4.15250
Negotiation of Intracellular Membrane Barriers by TAT-Modified Gold Nanoparticles
Krpetic, Z., Saleemi, S., Prior, I. A., See, V., Qureshi, R., & Brust, M. (2011). Negotiation of Intracellular Membrane Barriers by TAT-Modified Gold Nanoparticles. ACS NANO, 5(6), 5195-5201. doi:10.1021/nn201369k
A TACC3/ch-TOG/clathrin complex stabilises kinetochore fibres by inter-microtubule bridging
Booth, D. G., Hood, F. E., Prior, I. A., & Royle, S. J. (2011). A TACC3/ch-TOG/clathrin complex stabilises kinetochore fibres by inter-microtubule bridging. EMBO JOURNAL, 30(5), 906-919. doi:10.1038/emboj.2011.15
Magnetic CoPt nanoparticles as MRI contrast agent for transplanted neural stem cells detection
Meng, X., Seton, H. C., Lu, L. T., Prior, I. A., Thanh, N. T. K., & Song, B. (2011). Magnetic CoPt nanoparticles as MRI contrast agent for transplanted neural stem cells detection. NANOSCALE, 3(3), 977-984. doi:10.1039/c0nr00846j
2010
Highly Stable Dextran-Coated Quantum Dots for Biomolecular Detection and Cellular Imaging
Wilson, R., Spiller, D. G., Beckett, A., Prior, I. A., & See, V. (2010). Highly Stable Dextran-Coated Quantum Dots for Biomolecular Detection and Cellular Imaging. CHEMISTRY OF MATERIALS, 22(23), 6361-6369. doi:10.1021/cm1023635
Inflicting Controlled Nonthermal Damage to Subcellular Structures by Laser-Activated Gold Nanoparticles
Krpetic, Z., Nativo, P., See, V., Prior, I. A., Brust, M., & Volk, M. (2010). Inflicting Controlled Nonthermal Damage to Subcellular Structures by Laser-Activated Gold Nanoparticles. NANO LETTERS, 10(11), 4549-4554. doi:10.1021/nl103142t
Inflicting Controlled Nonthermal Damage to Subcellular Structures by Laser-Activated Gold Nanoparticles
Krpetić, Ž., Nativo, P., Sée, V., Prior, I. A., Brust, M., & Volk, M. (2010). Inflicting Controlled Nonthermal Damage to Subcellular Structures by Laser-Activated Gold Nanoparticles. Nano Letters, 10(11), 4549-4554. doi:10.1021/nl103142t
Regulatory activity of polyunsaturated fatty acids in T-cell signaling
Kim, W., Khan, N. A., McMurray, D. N., Prior, I. A., Wang, N., & Chapkin, R. S. (2010). Regulatory activity of polyunsaturated fatty acids in T-cell signaling. PROGRESS IN LIPID RESEARCH, 49(3), 250-261. doi:10.1016/j.plipres.2010.01.002
Ultrastructural examination of tissue in a patient with alkaptonuric arthropathy reveals a distinct pattern of binding of ochronotic pigment
Taylor, A. M., Wlodarski, B., Prior, I. A., Wilson, P. J. M., Jarvis, J. C., Ranganath, L. R., & Gallagher, J. A. (2010). Ultrastructural examination of tissue in a patient with alkaptonuric arthropathy reveals a distinct pattern of binding of ochronotic pigment. Rheumatology, 49(7), 1412-1414. doi:10.1093/rheumatology/keq027
Ultrastructural examination of tissue in a patient with alkaptonuric arthropathy reveals a distinct pattern of binding of ochronotic pigment
Taylor, A. M., Wlodarski, B., Prior, I. A., Wilson, P. J. M., Jarvis, J. C., Ranganath, L. R., & Gallagher, J. A. (2010). Ultrastructural examination of tissue in a patient with alkaptonuric arthropathy reveals a distinct pattern of binding of ochronotic pigment. RHEUMATOLOGY, 49(7), 1412-1414. doi:10.1093/rheumatology/keq027
Phosphatome profiling reveals PTPN2, PTPRJ and PTEN as potent negative regulators of PKB/Akt activation in Ras-mutated cancer cells
Omerovic, J., Clague, M. J., & Prior, I. A. (2010). Phosphatome profiling reveals PTPN2, PTPRJ and PTEN as potent negative regulators of PKB/Akt activation in Ras-mutated cancer cells. BIOCHEMICAL JOURNAL, 426, 65-72. doi:10.1042/BJ20091413
Intracellular Delivery and Fate of Peptide-Capped Gold Nanoparticles
Cesbron, Y., See, V., Free, P., Nativo, P., Shaheen, U., Rigden, D. J., . . . Levy, R. (2010). Intracellular Delivery and Fate of Peptide-Capped Gold Nanoparticles. In BIOPHYSICAL JOURNAL Vol. 98 (pp. 203A). doi:10.1016/j.bpj.2009.12.1081
Laser-induced Delivery of Gold Nanoparticles into Living Cells
Nativo, P., Brust, M., See, V., Prior, I., & Volk, M. (2010). Laser-induced Delivery of Gold Nanoparticles into Living Cells. In B. Wyborn (Ed.), Central Laser Facility Annual Report 2008/09 (pp. 190-192). Didcot: Science and Technology Facilities Council.
2009
Ribosome-free Terminals of Rough ER Allow Formation of STIM1 Puncta and Segregation of STIM1 from IP<sub>3</sub> Receptors
Lur, G., Haynes, L. P., Prior, I. A., Gerasimenko, O. V., Feske, S., Petersen, O. H., . . . Tepikin, A. V. (2009). Ribosome-free Terminals of Rough ER Allow Formation of STIM1 Puncta and Segregation of STIM1 from IP<sub>3</sub> Receptors. CURRENT BIOLOGY, 19(19), 1648-1653. doi:10.1016/j.cub.2009.07.072
Cathepsin L Digestion of Nanobioconjugates upon Endocytosis
See, V., Free, P., Cesbron, Y., Nativo, P., Shaheen, U., Rigden, D. J., . . . Levy, R. (2009). Cathepsin L Digestion of Nanobioconjugates upon Endocytosis. ACS NANO, 3(9), 2461-2468. doi:10.1021/nn9006994
Variant shape growth of nanoparticles of metallic Fe-Pt, Fe-Pd and Fe-Pt-Pd alloys
Ung, D., Tung, L. D., Caruntu, G., Delaportas, D., Alexandrou, I., Prior, I. A., & Thanh, N. T. K. (2009). Variant shape growth of nanoparticles of metallic Fe-Pt, Fe-Pd and Fe-Pt-Pd alloys. CRYSTENGCOMM, 11(7), 1309-1316. doi:10.1039/b823290n
A reliable method for attaching biological molecules to layer-by-layer self-assemblies
Wilson, R., Mehrabi, M., Prior, I. A., Beckett, A., & Hutchinson, A. (2009). A reliable method for attaching biological molecules to layer-by-layer self-assemblies. CHEMICAL COMMUNICATIONS, (18), 2487-2489. doi:10.1039/b822688a
Connexin expression and gap junctional coupling in human cumulus cells: contribution to embryo quality
Wang, H. -X., Tong, D., El-Gehani, F., Tekpetey, F. R., & Kidder, G. M. (2009). Connexin expression and gap junctional coupling in human cumulus cells: contribution to embryo quality. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE, 13(5), 972-984. doi:10.1111/j.1582-4934.2008.00373.x
Three-dimensional electron microscopic reconstruction of intracellular organellar arrangements in vascular smooth muscle--further evidence of nanospaces and contacts.
Tong, W. C., Sweeney, M., Jones, C. J. P., Zhang, H., O'Neill, S. C., Prior, I., & Taggart, M. J. (2009). Three-dimensional electron microscopic reconstruction of intracellular organellar arrangements in vascular smooth muscle--further evidence of nanospaces and contacts.. Journal of cellular and molecular medicine, 13(5), 995-998. doi:10.1111/j.1582-4934.2009.00770.x
Compartmentalized signalling: Ras proteins and signalling nanoclusters
Omerovic, J., & Prior, I. A. (2009). Compartmentalized signalling: Ras proteins and signalling nanoclusters. FEBS JOURNAL, 276(7), 1817-1825. doi:10.1111/j.1742-4658.2009.06928.x
Compartmentalized signalling: cAMP, calcium and Ras
Prior, I. A. (2009). Compartmentalized signalling: cAMP, calcium and Ras. FEBS JOURNAL, 276(7), 1789. doi:10.1111/j.1742-4658.2009.06925.x
Ras acylation, compartmentalization and signaling nanoclusters (Review)
Henis, Y. I., Hancock, J. F., & Prior, I. A. (2009). Ras acylation, compartmentalization and signaling nanoclusters (Review). MOLECULAR MEMBRANE BIOLOGY, 26(1-2), 80-92. doi:10.1080/09687680802649582
Three-dimensional electron microscopic reconstruction of sarcoplasmic reticular arrangement in vascular smooth muscle with respect to mitochondria and the nucleus - further evidence of nanospaces and contacts
Tong, W. C., Sweeney, M., Jones, C. J. P., Zhang, H., O'Neill, S. C., Prior, I., & Taggart, M. J. (2009). Three-dimensional electron microscopic reconstruction of sarcoplasmic reticular arrangement in vascular smooth muscle with respect to mitochondria and the nucleus - further evidence of nanospaces and contacts. J. Cellular Mol. Med., in press.
2008
Uptake and intracellular fate of surface-modified gold nanoparticles
Nativo, P., Prior, I. A., & Brust, M. (2008). Uptake and intracellular fate of surface-modified gold nanoparticles. ACS NANO, 2(8), 1639-1644. doi:10.1021/nn800330a
S-nitrosylation of syntaxin 1 at Cys<SUP>145</SUP> is a regulatory switch controlling Munc18-1 binding
Palmer, Z. J., Duncan, R. R., Johnson, J. R., Lian, L. -Y., Mello, L. V., Booth, D., . . . Morgan, A. (2008). S-nitrosylation of syntaxin 1 at Cys<SUP>145</SUP> is a regulatory switch controlling Munc18-1 binding. BIOCHEMICAL JOURNAL, 413, 479-491. doi:10.1042/BJ20080069
Ras isoform abundance and signalling in human cancer cell lines
Omerovic, J., Hammond, D. E., Clague, M. J., & Prior, I. A. (2008). Ras isoform abundance and signalling in human cancer cell lines. ONCOGENE, 27(19), 2754-2762. doi:10.1038/sj.onc.1210925
Palmitoylation and localisation of RAS isoforms are modulated by the hypervariable linker domain
Laude, A. J., & Prior, I. A. (2008). Palmitoylation and localisation of RAS isoforms are modulated by the hypervariable linker domain. JOURNAL OF CELL SCIENCE, 121(4), 421-427. doi:10.1242/jcs.020107
Docosahexaenoic acid alters the size and distribution of cell surface microdomains
Chapkin, R. S., Wang, N., Fan, Y. -Y., Lupton, J. R., & Prior, I. A. (2008). Docosahexaenoic acid alters the size and distribution of cell surface microdomains. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES, 1778(2), 466-471. doi:10.1016/j.bbamem.2007.11.003
2007
The Vpu-regulated endocytosis of HIV-1 Gag is clathrin-independent
Harila, K., Salminen, A., Prior, I., Hinkula, J., & Suomalainen, M. (2007). The Vpu-regulated endocytosis of HIV-1 Gag is clathrin-independent. VIROLOGY, 369(2), 299-308. doi:10.1016/j.virol.2007.08.009
A simple method for preparing spectrally encoded magnetic beads for multiplexed detection
Wilson, R., Spiller, D. G., Prior, I. A., Veltkamp, K. J., & Hutchinson, A. (2007). A simple method for preparing spectrally encoded magnetic beads for multiplexed detection. ACS NANO, 1(5), 487-493. doi:10.1021/nn700289m
Magnetic microspheres encoded with photoluminescent quantum dots for multiplexed detection
Wilson, R., Spiller, D. G., Prior, I. A., Bhatt, R., & Hutchinson, A. (2007). Magnetic microspheres encoded with photoluminescent quantum dots for multiplexed detection. JOURNAL OF MATERIALS CHEMISTRY, 17(41), 4400-4406. doi:10.1039/b708174j
Ras proteins: paradigms for compartmentalised and isoform-specific signalling
Omerovic, J., Laude, A. J., & Prior, I. A. (2007). Ras proteins: paradigms for compartmentalised and isoform-specific signalling. CELLULAR AND MOLECULAR LIFE SCIENCES, 64(19-20), 2575-2589. doi:10.1007/s00018-007-7133-8
Activation of trypsinogen in large endocytic vacuoles of pancreatic acinar cells
Sherwood, M. W., Prior, I. A., Voronina, S. G., Barrow, S. L., Woodsmith, J. D., Gerasimenko, O. V., . . . Tepikin, A. V. (2007). Activation of trypsinogen in large endocytic vacuoles of pancreatic acinar cells. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 104(13), 5674-5679. doi:10.1073/pnas.0700951104
2006
Control of growth factor receptor dynamics by reversible ubiquitination
Urbe, S., McCullough, J., Row, P. E., Prior, I. A., Welchman, R., & Clague, M. J. (2006). Control of growth factor receptor dynamics by reversible ubiquitination. BIOCHEMICAL SOCIETY TRANSACTIONS, 34, 754-756. doi:10.1042/BST0340754
The ubiquitin isopeptidase UBPY regulates endosomal ubiquitin dynamics and is essential for receptor down-regulation
Row, P. E., Prior, I. A., McCullough, J., Clague, M. J., & Urbé, S. (2006). The ubiquitin isopeptidase UBPY regulates endosomal ubiquitin dynamics and is essential for receptor down-regulation. JOURNAL OF BIOLOGICAL CHEMISTRY, 281(18), 12618-12624. doi:10.1074/jbc.M512615200
Vpu and Tsg101 regulate intracellular targeting of the human immunodeficiency virus type 1 core protein precursor Pr55<i><SUP>gag</SUP></i>
Harila, K., Prior, I., Sjöberg, M., Salminen, A., Hinkula, J., & Suomalainen, M. (2006). Vpu and Tsg101 regulate intracellular targeting of the human immunodeficiency virus type 1 core protein precursor Pr55<i><SUP>gag</SUP></i>. JOURNAL OF VIROLOGY, 80(8), 3765-3772. doi:10.1128/JVI.80.8.3765-3772.2006
2005
Traffic of Kv4 K<SUP>+</SUP> channels mediated by KChlP1 is via a novel post-ER vesicular pathway
Hasdemir, B., Fitzgerald, D. J., Prior, I. A., Tepikin, A. V., & Burgoyne, R. D. (2005). Traffic of Kv4 K<SUP>+</SUP> channels mediated by KChlP1 is via a novel post-ER vesicular pathway. JOURNAL OF CELL BIOLOGY, 171(3), 459-469. doi:10.1083/jcb.200506005
Electron microscopic imaging of Ras signaling domains
Hancock, J. F., & Prior, I. A. (2005). Electron microscopic imaging of Ras signaling domains. METHODS, 37(2), 165-172. doi:10.1016/j.ymeth.2005.05.018
Individual palmitoyl residues serve distinct roles in H-ras trafficking, microlocalization, and signaling
Roy, S., Plowman, S., Rotblat, B., Prior, I. A., Muncke, C., Grainger, S., . . . Hancock, J. F. (2005). Individual palmitoyl residues serve distinct roles in H-ras trafficking, microlocalization, and signaling. MOLECULAR AND CELLULAR BIOLOGY, 25(15), 6722-6733. doi:10.1128/MCB.25.15.6722-6733.2005
2004
Three separable domains regulate GTP-dependent association of H-ras with the plasma membrane
Rotblat, B., Prior, I. A., Muncke, C., Parton, R. G., Kloog, Y., Henis, Y. I., & Hancock, J. F. (2004). Three separable domains regulate GTP-dependent association of H-ras with the plasma membrane. MOLECULAR AND CELLULAR BIOLOGY, 24(15), 6799-6810. doi:10.1128/MCB.24.15.6799-6810.2004
Plasma membrane microdomains: organization, function and trafficking (Review)
Laude, A. J., & Prior, I. A. (2004). Plasma membrane microdomains: organization, function and trafficking (Review). MOLECULAR MEMBRANE BIOLOGY, 21(3), 193-205. doi:10.1080/09687680410001700517
2003
C-terminal sequences in R-Ras are involved in integrin regulation and in plasma membrane microdomain distribution
Hansen, M., Prior, I. A., Hughes, P. E., Oertli, B., Chou, F. L., Willumsen, B. M., . . . Ginsberg, M. H. (2003). C-terminal sequences in R-Ras are involved in integrin regulation and in plasma membrane microdomain distribution. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 311(4), 829-838. doi:10.1016/j.bbrc.2003.10.074
Caveolin interacts with the angiotensin II type 1 receptor during exocytic transport but not at the plasma membrane
Wyse, B. D., Prior, I. A., Qian, H. W., Morrow, I. C., Nixon, S., Muncke, C., . . . Hancock, J. F. (2003). Caveolin interacts with the angiotensin II type 1 receptor during exocytic transport but not at the plasma membrane. JOURNAL OF BIOLOGICAL CHEMISTRY, 278(26), 23738-23746. doi:10.1074/jbc.M212892200
Observing cell surface signaling domains using electron microscopy.
Prior, I. A., Parton, R. G., & Hancock, J. F. (2003). Observing cell surface signaling domains using electron microscopy.. Science's STKE : signal transduction knowledge environment, 2003(177), PL9. doi:10.1126/stke.2003.177.pl9
Direct visualization of Ras proteins in spatially distinct cell surface microdomains
Prior, I. A., Muncke, C., Parton, R. G., & Hancock, J. F. (2003). Direct visualization of Ras proteins in spatially distinct cell surface microdomains. JOURNAL OF CELL BIOLOGY, 160(2), 165-170. doi:10.1083/jcb.200209091
2002
Flotillin-1/Reggie-2 traffics to surface raft domains via a novel Golgi-independent pathway - Identification of a novel membrane targeting domain and a role for palmitoylation
Morrow, I. C., Rea, S., Martin, S., Prior, I. A., Prohaska, R., Hancock, J. F., . . . Parton, R. G. (2002). Flotillin-1/Reggie-2 traffics to surface raft domains via a novel Golgi-independent pathway - Identification of a novel membrane targeting domain and a role for palmitoylation. JOURNAL OF BIOLOGICAL CHEMISTRY, 277(50), 48834-48841. doi:10.1074/jbc.M209082200
Inhibition of lipid raft-dependent signaling by a dystrophy-associated mutant of caveolin-3
Carozzi, A. J., Roy, S., Morrow, I. C., Pol, A., Wyse, B., Clyde-Smith, J., . . . Parton, R. G. (2002). Inhibition of lipid raft-dependent signaling by a dystrophy-associated mutant of caveolin-3. JOURNAL OF BIOLOGICAL CHEMISTRY, 277(20), 17944-17949. doi:10.1074/jbc.M110879200
2001
Compartmentalization of Ras proteins.
Prior, I. A., & Hancock, J. F. (2001). Compartmentalization of Ras proteins.. Journal of cell science, 114(Pt 9), 1603-1608. doi:10.1242/jcs.114.9.1603
GTP-dependent segregation of H-ras from lipid rafts is required for biological activity
Prior, I. A., Harding, A., Yan, J., Sluimer, J., Parton, R. G., & Hancock, J. F. (2001). GTP-dependent segregation of H-ras from lipid rafts is required for biological activity. NATURE CELL BIOLOGY, 3(4), 368-375. doi:10.1038/35070050
Compartmentalization of Ras proteins
Prior, I. A., & Hancock, J. F. (2001). Compartmentalization of Ras proteins. J Cell Sci, 114(Pt 9), 1603-1608. Retrieved from http://www.ncbi.nlm.nih.gov/
Compartmentalization of Ras proteins
Prior, I. A., & Hancock, J. F. (2001). Compartmentalization of Ras proteins. JOURNAL OF CELL SCIENCE, 114(9), 1603-1608. Retrieved from https://www.webofscience.com/
Which Ras rides the raft? Reply
Prior, I. A., Parton, R. G., & Hancock, J. F. (2001). Which Ras rides the raft? Reply. NATURE CELL BIOLOGY, 3(8), E172. doi:10.1038/35087100
2000
Detection of thiol modification following generation of reactive nitrogen species: analysis of synaptic vesicle proteins
Prior, I. A., & Clague, M. J. (2000). Detection of thiol modification following generation of reactive nitrogen species: analysis of synaptic vesicle proteins. BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS, 1475(3), 281-286. doi:10.1016/S0304-4165(00)00078-7
H-ras but not K-ras traffics to the plasma membrane through the exocytic pathway
Apolloni, A., Prior, I. A., Lindsay, M., Parton, R. G., & Hancock, J. F. (2000). H-ras but not K-ras traffics to the plasma membrane through the exocytic pathway. MOLECULAR AND CELLULAR BIOLOGY, 20(7), 2475-2487. doi:10.1128/MCB.20.7.2475-2487.2000
1999
Localization of a class II phosphatidylinositol 3-kinase, PI3KC2alpha, to clathrin-coated vesicles.
Prior, I. A., & Clague, M. J. (1999). Localization of a class II phosphatidylinositol 3-kinase, PI3KC2alpha, to clathrin-coated vesicles.. Molecular cell biology research communications : MCBRC, 1(2), 162-166. doi:10.1006/mcbr.1999.0126
1998
Evaluation of X-ray microfluorescence spectrometry for the elemental analysis of firearm discharge residues
Flynn, J., Stoilovic, M., Lennard, C., Prior, L., & Kobus, H. (1998). Evaluation of X-ray microfluorescence spectrometry for the elemental analysis of firearm discharge residues. FORENSIC SCIENCE INTERNATIONAL, 97(1), 21-36. doi:10.1016/S0379-0738(98)00127-3
1997
Glutamate uptake occurs at an early stage of synaptic vesicle recycling
Prior, I. A., & Clague, M. J. (1997). Glutamate uptake occurs at an early stage of synaptic vesicle recycling. CURRENT BIOLOGY, 7(5), 353-356. doi:10.1016/S0960-9822(06)00159-X