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Prof Jamie Kirkham
B.Sc, M.Sc, PhD.

Publications

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2024

FERN: Is it possible to conduct a Randomised controlled trial of Intervention or Expectant Management for Early Onset Selective Fetal Growth Restriction in Monochorionic Twin Pregnancy: protocol for a prospective, mixed methods feasibility study

Sharp, A. (2024). FERN: Is it possible to conduct a Randomised controlled trial of Intervention or Expectant Management for Early Onset Selective Fetal Growth Restriction in Monochorionic Twin Pregnancy: protocol for a prospective, mixed methods feasibility study. BMJ Open.

Journal article

Core outcome set developers should consider and specify the level of granularity of outcome domains.

Kottner, J., Beaton, D., Clarke, M., Dodd, S., Kirkham, J., Lange, T., . . . Williamson, P. (2024). Core outcome set developers should consider and specify the level of granularity of outcome domains.. Journal of clinical epidemiology, 169, 111307. doi:10.1016/j.jclinepi.2024.111307

DOI
10.1016/j.jclinepi.2024.111307
Journal article

Study found increasing use of core outcome sets in Cochrane systematic reviews and identified facilitators and barriers.

Saldanha, I. J., Hughes, K. L., Dodd, S., Lasserson, T., Kirkham, J. J., Wu, Y., . . . Williamson, P. R. (2024). Study found increasing use of core outcome sets in Cochrane systematic reviews and identified facilitators and barriers.. Journal of clinical epidemiology, 169, 111277. doi:10.1016/j.jclinepi.2024.111277

DOI
10.1016/j.jclinepi.2024.111277
Journal article

Protocol for the development of a tool (INSPECT-SR) to identify problematic randomised controlled trials in systematic reviews of health interventions.

Wilkinson, J., Heal, C., Antoniou, G. A., Flemyng, E., Alfirevic, Z., Avenell, A., . . . Kirkham, J. J. (2024). Protocol for the development of a tool (INSPECT-SR) to identify problematic randomised controlled trials in systematic reviews of health interventions.. BMJ open, 14(3), e084164. doi:10.1136/bmjopen-2024-084164

DOI
10.1136/bmjopen-2024-084164
Journal article

COHESION: a core outcome set for the treatment of neonatal encephalopathy.

Quirke, F. A., Ariff, S., Battin, M. R., Bernard, C., Biesty, L., Bloomfield, F. H., . . . Devane, D. (2024). COHESION: a core outcome set for the treatment of neonatal encephalopathy.. Pediatric research, 95(4), 922-930. doi:10.1038/s41390-023-02938-y

DOI
10.1038/s41390-023-02938-y
Journal article

Optimising research for neonates with encephalopathy: the role of core outcome sets.

Devane, D., Ariff, S., Battin, M. R., Biesty, L., Bloomfield, F. H., Daly, M., . . . Quirke, F. A. (2024). Optimising research for neonates with encephalopathy: the role of core outcome sets.. Pediatric research, 95(4), 869-870. doi:10.1038/s41390-023-03006-1

DOI
10.1038/s41390-023-03006-1
Journal article

Validation of the brain injury associated visual impairment - impact questionnaire (BIVI-IQ).

Hepworth, L. R., Kirkham, J. J., Perkins, E., Helliwell, B., Howard, C., Liptrot, M., . . . Rowe, F. J. (2024). Validation of the brain injury associated visual impairment - impact questionnaire (BIVI-IQ).. Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation, 33(3), 777-791. doi:10.1007/s11136-023-03565-0

DOI
10.1007/s11136-023-03565-0
Journal article

Core outcome sets for trials of interventions to prevent and to treat multimorbidity in low- and middle-income countries: the COSMOS study.

DOI
10.1101/2024.01.29.24301589
Preprint

2023

ROB-ME: a tool for assessing risk of bias due to missing evidence in systematic reviews with meta-analysis.

Page, M. J., Sterne, J. A. C., Boutron, I., Hróbjartsson, A., Kirkham, J. J., Li, T., . . . Higgins, J. P. T. (2023). ROB-ME: a tool for assessing risk of bias due to missing evidence in systematic reviews with meta-analysis.. BMJ (Clinical research ed.), 383, e076754. doi:10.1136/bmj-2023-076754

DOI
10.1136/bmj-2023-076754
Journal article

Protocol for the development of a tool (INSPECT-SR) to identify problematic randomised controlled trials in systematic reviews of health interventions.

DOI
10.1101/2023.09.21.23295626
Preprint

Gynecological trials frequently exclude people based on their symptoms rather than their condition: a systematic review of Cochrane reviews and their component trials.

Stocking, K., Watson, A., Kirkham, J. J., Wilkinson, J., & Vail, A. (2023). Gynecological trials frequently exclude people based on their symptoms rather than their condition: a systematic review of Cochrane reviews and their component trials.. Journal of clinical epidemiology, 163, 29-36. doi:10.1016/j.jclinepi.2023.09.012

DOI
10.1016/j.jclinepi.2023.09.012
Journal article

PROTOCOL FOR THE DEVELOPMENT OF A CORE OUTCOME SET FOR RESPECTFUL MATERNAL AND NEWBORN CARE IN A LOW-MIDDLE INCOME SETTING

DOI
10.1101/2023.05.31.23290715
Preprint

Systematic review search strategies are poorly described and not reproducible: a cross-sectional meta-research study

DOI
10.1101/2023.05.11.23289873
Preprint

Trial participants are frequently excluded based on their symptoms rather than their condition: A systematic review of Cochrane reviews and their component trials

DOI
10.1101/2023.04.21.23288922
Preprint

How do IVF patients interpret claims about fertility treatments? A randomised survey experiment

Carrick, M., Wilkinson, J., Polyakov, A., Kirkham, J., & Lensen, S. (2023). How do IVF patients interpret claims about fertility treatments? A randomised survey experiment. Human Fertility, 1-8. doi:10.1080/14647273.2023.2191222

DOI
10.1080/14647273.2023.2191222
Journal article

2022

CHRISTMAS 2022: THE SCIENTIST On the 12th Day of Christmas, a Statistician Sent to Me ...

Riley, R. D., Cole, T. J., Deeks, J., Kirkham, J. J., Morris, J., Perera, R., . . . Collins, G. S. (2022). CHRISTMAS 2022: THE SCIENTIST On the 12th Day of Christmas, a Statistician Sent to Me .... BMJ-BRITISH MEDICAL JOURNAL, 379. doi:10.1136/bmj-2022-072883

DOI
10.1136/bmj-2022-072883
Journal article

Comparison of published core outcome sets with outcomes recommended in regulatory guidance from the US Food and Drug Administration and European Medicines Agency: cross sectional analysis.

Saldanha, I. J., Dodd, S., Fish, R., Gorst, S. L., Hall, D. A., Jacobsen, P., . . . Williamson, P. R. (2022). Comparison of published core outcome sets with outcomes recommended in regulatory guidance from the US Food and Drug Administration and European Medicines Agency: cross sectional analysis.. BMJ medicine, 1(1), e000233. doi:10.1136/bmjmed-2022-000233

DOI
10.1136/bmjmed-2022-000233
Journal article

Protocol for the development of a meta-core outcome set for stillbirth prevention and bereavement care following stillbirth

DOI
10.1101/2022.10.13.22281030
Preprint

Development of a core outcome set for basal cell carcinoma

Schlessinger, D. I., Reynolds, K. A., Dirr, M. A., Ibrahim, S. A., Yanes, A. F., Lazaroff, J. M., . . . Alam, M. (2022). Development of a core outcome set for basal cell carcinoma. JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, 87(3), 573-581. doi:10.1016/j.jaad.2022.04.059

DOI
10.1016/j.jaad.2022.04.059
Journal article

Development of core outcome sets and core outcome measures for central visual impairment, visual field loss and ocular motility disorders due to stroke: a Delphi and consensus study.

Rowe, F. J., Hepworth, L. R., & Kirkham, J. J. (2022). Development of core outcome sets and core outcome measures for central visual impairment, visual field loss and ocular motility disorders due to stroke: a Delphi and consensus study.. BMJ open, 12(3), e056792. doi:10.1136/bmjopen-2021-056792

DOI
10.1136/bmjopen-2021-056792
Journal article

2021

Cross-sectional study of preprints and final journal publications from COVID-19 studies: discrepancies in results reporting and spin in interpretation

Bero, L., Lawrence, R., Leslie, L., Chiu, K., McDonald, S., Page, M. J., . . . Featherstone, R. (2021). Cross-sectional study of preprints and final journal publications from COVID-19 studies: discrepancies in results reporting and spin in interpretation. BMJ OPEN, 11(7). doi:10.1136/bmjopen-2021-051821

DOI
10.1136/bmjopen-2021-051821
Journal article

Improving peer review of systematic reviews by involving librarians and information specialists: protocol for a randomized controlled trial

DOI
10.31222/osf.io/92n4w
Preprint

Core outcome set for three ophthalmic conditions: a healthcare professional and patient consensus on core outcome sets for amblyopia, ocular motility and strabismus (COSAMS Study).

Al-Jabri, S., Rowe, F. J., & Kirkham, J. J. (2021). Core outcome set for three ophthalmic conditions: a healthcare professional and patient consensus on core outcome sets for amblyopia, ocular motility and strabismus (COSAMS Study).. BMJ Open, 11(5), e042403. doi:10.1136/bmjopen-2020-042403

DOI
10.1136/bmjopen-2020-042403
Journal article

Development of a core outcome set for multimorbidity trials in low- and middle-income countries (COSMOS): Study Protocol

Boehnke, J. R., Rana, R. Z., Kirkham, J. J., Rose, L., Agarwal, G., Barbui, C., . . . Siddiqi, N. (2021). Development of a core outcome set for multimorbidity trials in low- and middle-income countries (COSMOS): Study Protocol. doi:10.1101/2021.03.23.21253685

DOI
10.1101/2021.03.23.21253685
Journal article

2020

Systematic examination of preprint platforms for use in the medical and biomedical sciences setting

Kirkham, J. J., Penfold, N. C., Murphy, F., Boutron, I., Ioannidis, J. P., Polka, J., & Moher, D. (2020). Systematic examination of preprint platforms for use in the medical and biomedical sciences setting. BMJ OPEN, 10(12). doi:10.1136/bmjopen-2020-041849

DOI
10.1136/bmjopen-2020-041849
Journal article

Assessing the relevance and uptake of core outcome sets (an agreed minimum collection of outcomes to measure in research studies) in Cochrane systematic reviews: a review

Williamson, P. R., de Ávila Oliveira, R., Clarke, M., Gorst, S. L., Hughes, K., Kirkham, J. J., . . . Schmitt, J. (2020). Assessing the relevance and uptake of core outcome sets (an agreed minimum collection of outcomes to measure in research studies) in Cochrane systematic reviews: a review. BMJ open, 10(9). doi:10.1136/bmjopen-2019-036562

DOI
10.1136/bmjopen-2019-036562
Journal article

Assessing uptake of the Harmonising Outcome Measures for Eczema (HOME) Core Outcome Set and recommended instruments

Vincent, R., Chalmers, J. R., McWilliams, C., Thomas, K. S., Dodd, S., Rogers, N., . . . Kirkham, J. J. (2020). Assessing uptake of the Harmonising Outcome Measures for Eczema (HOME) Core Outcome Set and recommended instruments. BRITISH JOURNAL OF DERMATOLOGY, 183(3), 566-568. doi:10.1111/bjd.19030

DOI
10.1111/bjd.19030
Journal article

Assessing the effect of interventions for axial spondyloarthritis according to the endorsed ASAS/OMERACT core outcome set: a meta-research study of trials included in Cochrane reviews

Andreasen, R. A., Kristensen, L. E., Baraliakos, X., Strand, V., Mease, P. J., de Wit, M., . . . Christensen, R. (2020). Assessing the effect of interventions for axial spondyloarthritis according to the endorsed ASAS/OMERACT core outcome set: a meta-research study of trials included in Cochrane reviews. ARTHRITIS RESEARCH & THERAPY, 22(1). doi:10.1186/s13075-020-02262-4

DOI
10.1186/s13075-020-02262-4
Journal article

A systematic examination of preprint platforms for use in the medical and biomedical sciences setting

DOI
10.1101/2020.04.27.063578
Preprint

Core Outcome Set for Actinic Keratosis Clinical Trials

Reynolds, K. A., Schlessinger, D. I., Vasic, J., Iyengar, S., Qaseem, Y., Behshad, R., . . . Alam, M. (2020). Core Outcome Set for Actinic Keratosis Clinical Trials. JAMA DERMATOLOGY, 156(3), 326-333. doi:10.1001/jamadermatol.2019.4212

DOI
10.1001/jamadermatol.2019.4212
Journal article

2019

Use of composite outcomes facilitate core outcome set uptake in rheumatoid arthritis trials

Kirkham, J., Christensen, R., & Boers, M. (2020). Use of composite outcomes facilitate core outcome set uptake in rheumatoid arthritis trials. ANNALS OF THE RHEUMATIC DISEASES, 79(2), 301-+. doi:10.1136/annrheumdis-2019-216256

DOI
10.1136/annrheumdis-2019-216256
Journal article

Assessing the impact of a research funder’s recommendation to consider core outcome sets

Hughes, K. L., Kirkham, J., Clarke, M., & Williamson, P. R. (2019). Assessing the impact of a research funder’s recommendation to consider core outcome sets. PLoS One, 14(9). doi:10.1371/journal.pone.0222418

DOI
10.1371/journal.pone.0222418
Journal article

RoB 2: a revised tool for assessing risk of bias in randomised trials

Sterne, J. A. C., Savovic, J., Page, M. J., Elbers, R. G., Blencowe, N. S., Boutron, I., . . . Higgins, J. P. T. (2019). RoB 2: a revised tool for assessing risk of bias in randomised trials. BMJ-BRITISH MEDICAL JOURNAL, 366. doi:10.1136/bmj.l4898

DOI
10.1136/bmj.l4898
Journal article

Protocol for the development of the STrengthening the Reporting Of Pharmacogenetic Studies (STROPS) guideline: checklist of items for reporting pharmacogenetic studies

Richardson, M., Kirkham, J. J., Dwan, K. M., Sloan, D. J., Davies, G., & Jorgensen, A. (2019). Protocol for the development of the STrengthening the Reporting Of Pharmacogenetic Studies (STROPS) guideline: checklist of items for reporting pharmacogenetic studies. BMJ OPEN, 9(7). doi:10.1136/bmjopen-2019-030212

DOI
10.1136/bmjopen-2019-030212
Journal article

Systematic Review: Outcomes and Adverse Events From Randomised Trials in Crohn's Disease

Catt, H., Hughes, D., Kirkham, J., & Bodger, K. (2019). Systematic Review: Outcomes and Adverse Events From Randomised Trials in Crohn's Disease. Alimentary Pharmacology and Therapeutics, 49(8), 978-996. doi:10.1111/apt.15174

DOI
10.1111/apt.15174
Journal article

Pain Measurement in Rheumatic and Musculoskeletal Diseases: Where To Go from Here? Report from a Special Interest Group at OMERACT 2018

Chiarotto, A., Kaiser, U., Choy, E., Christensen, R., Conaghan, P. G., Cowern, M., . . . Mease, P. J. (2019). Pain Measurement in Rheumatic and Musculoskeletal Diseases: Where To Go from Here? Report from a Special Interest Group at OMERACT 2018. JOURNAL OF RHEUMATOLOGY, 46(10), 1355-1359. doi:10.3899/jrheum.181099

DOI
10.3899/jrheum.181099
Journal article

Undertaking trials methodology research using data from clinical trial registries: an exemplar related to core outcome set uptake

Kirkham, J. J., Williamson, P., & Clarke, M. (2019). Undertaking trials methodology research using data from clinical trial registries: an exemplar related to core outcome set uptake. In TRIALS Vol. 20. Retrieved from https://www.webofscience.com/

Conference Paper

2018

QUANTITATIVE BENEFIT-RISK MODELLING OF BIOSIMILARS: A CASE STUDY OF INFLIXIMAB IN CROHN'S DISEASE.

Catt, H., Bodger, K., Kirkham, J., & Hughes, D. A. (2018). QUANTITATIVE BENEFIT-RISK MODELLING OF BIOSIMILARS: A CASE STUDY OF INFLIXIMAB IN CROHN'S DISEASE.. In VALUE IN HEALTH Vol. 21 (pp. S380). doi:10.1016/j.jval.2018.09.2262

DOI
10.1016/j.jval.2018.09.2262
Conference Paper

The transition of adolescents with juvenile idiopathic arthritis or epilepsy from paediatric health-care services to adult health-care services: A scoping review of the literature and a synthesis of the evidence

Burke, L., Kirkham, J., Arnott, J., Gray, V., Peak, M., & WBeresford, M. (2018). The transition of adolescents with juvenile idiopathic arthritis or epilepsy from paediatric health-care services to adult health-care services: A scoping review of the literature and a synthesis of the evidence. JOURNAL OF CHILD HEALTH CARE, 22(3), 332-358. doi:10.1177/1367493517753330

DOI
10.1177/1367493517753330
Journal article

A SYSTEMATIC REVIEW OF OUTCOMES AND ADVERSE EVENTS FOR RANDOMISED CONTROLLED TRIALS IN CROHN'S DISEASE

Catt, M. H., Hughes, D., Bodger, K., & Kirkham, J. (2018). A SYSTEMATIC REVIEW OF OUTCOMES AND ADVERSE EVENTS FOR RANDOMISED CONTROLLED TRIALS IN CROHN'S DISEASE. In GUT Vol. 67 (pp. A71). doi:10.1136/gutjnl-2018-BSGAbstracts.139

DOI
10.1136/gutjnl-2018-BSGAbstracts.139
Conference Paper

Core outcome sets in dermatology: report from the second meeting of the International Cochrane Skin Group Core Outcome Set Initiative

Kottner, J., Jacobi, L., Hahnel, E., Alam, M., Balzer, K., Beeckman, D., . . . Schmitt, J. (2018). Core outcome sets in dermatology: report from the second meeting of the International Cochrane Skin Group Core Outcome Set Initiative. BRITISH JOURNAL OF DERMATOLOGY, 178(4), E279-E285. doi:10.1111/bjd.16324

DOI
10.1111/bjd.16324
Journal article

Management of medial humeral epicondyle fractures in children: a structured review protocol for a systematic review of the literature and identification of a core outcome set using a Delphi survey

Dorman, S. L., Shelton, J. A., Stevenson, R. A., Linkman, K., Kirkham, J., & Perry, D. C. (2018). Management of medial humeral epicondyle fractures in children: a structured review protocol for a systematic review of the literature and identification of a core outcome set using a Delphi survey. TRIALS, 19. doi:10.1186/s13063-018-2472-3

DOI
10.1186/s13063-018-2472-3
Journal article

Are CONSORT checklists submitted by authors adequately reflecting what information is actually reported in published papers?

Blanco, D., Biggane, A. M., & Cobo, E. (2018). Are CONSORT checklists submitted by authors adequately reflecting what information is actually reported in published papers?. TRIALS, 19. doi:10.1186/s13063-018-2475-0

DOI
10.1186/s13063-018-2475-0
Journal article

Development of a consensus core dataset in juvenile dermatomyositis for clinical use to inform research.

McCann, L. J., Pilkington, C. A., Huber, A. M., Ravelli, A., Appelbe, D., Kirkham, J. J., . . . Beresford, M. W. (2018). Development of a consensus core dataset in juvenile dermatomyositis for clinical use to inform research.. Annals of the rheumatic diseases, 77(2), 241-250. doi:10.1136/annrheumdis-2017-212141

DOI
10.1136/annrheumdis-2017-212141
Journal article

A randomised trial comparing three Delphi feedback strategies found no evidence of a difference in a setting with high initial agreement.

MacLennan, S., Kirkham, J., Lam, T. B. L., & Williamson, P. R. (2018). A randomized trial comparing three Delphi feedback strategies found no evidence of a difference in a setting with high initial agreement. JOURNAL OF CLINICAL EPIDEMIOLOGY, 93, 1-8. doi:10.1016/j.jclinepi.2017.09.024

DOI
10.1016/j.jclinepi.2017.09.024
Journal article

2017

Multivariate and network meta-analysis of multiple outcomes and multiple treatments: rationale, concepts, and examples

Riley, R. D., Jackson, D., Salanti, G., Burke, D. L., Price, M., Kirkham, J., & White, I. R. (2017). Multivariate and network meta-analysis of multiple outcomes and multiple treatments: rationale, concepts, and examples. BMJ-BRITISH MEDICAL JOURNAL, 358. doi:10.1136/bmj.j3932

DOI
10.1136/bmj.j3932
Journal article

Do systematic reviews still exclude studies with "no relevant outcome data"?

Dwan, K. M., Williamson, P. R., & Kirkham, J. J. (2017). Do systematic reviews still exclude studies with "no relevant outcome data"?. BMJ (Clinical research ed.), 358, j3919. doi:10.1136/bmj.j3919

DOI
10.1136/bmj.j3919
Journal article

The COMET Handbook: version 1.0

Williamson, P., Altman, D. G., Bagley, H., Barnes, K. L., Blazeby, J. M., Brookes, S. T., . . . Young, B. (2017). The COMET Handbook: version 1.0. Trials, 18(Suppl 3), 50 pages. doi:10.1186/s13063-017-1978-4

DOI
10.1186/s13063-017-1978-4
Journal article

A methodological approach for assessing the uptake of core outcome sets using ClinicalTrials.gov: findings from a review of randomised controlled trials of rheumatoid arthritis.

Kirkham, J. J., Clarke, M., & Williamson, P. R. (2017). A methodological approach for assessing the uptake of core outcome sets using ClinicalTrials.gov: findings from a review of randomised controlled trials of rheumatoid arthritis.. BMJ: British Medical Journal, 357. doi:10.1136/bmj.j2262

DOI
10.1136/bmj.j2262
Journal article

Assessing the impact of a funder's recommendation on consideration and uptake of core outcome sets in funding applications

Barnes, K., Kirkham, J. J., Clarke, M., & Williamson, P. R. (2017). Assessing the impact of a funder's recommendation on consideration and uptake of core outcome sets in funding applications. In TRIALS Vol. 18. Retrieved from https://www.webofscience.com/

Conference Paper

Outcome selection in clinical trials - Looking back at the problems and moving forward with solutions

Williamson, P., Kirkham, J. K., Gamble, C., & Dwan, K. (2017). Outcome selection in clinical trials - Looking back at the problems and moving forward with solutions. In TRIALS Vol. 18. Retrieved from https://www.webofscience.com/

Conference Paper

Quantitative benefit-risk modelling of infliximab biosimilar inflectra versus reference product remicade in the treatment of Crohn's disease

Catt, H., Hughes, D., Bodger, K., & Kirkham, J. (2017). Quantitative benefit-risk modelling of infliximab biosimilar inflectra versus reference product remicade in the treatment of Crohn's disease. In TRIALS Vol. 18. Retrieved from https://www.webofscience.com/

Conference Paper

2016

Core Outcome Set–STAndards for Reporting: The COS-STAR Statement

Kirkham, J. J., Gorst, S., Altman, D. G., Blazeby, J. M., Clarke, M., Devane, D., . . . Williamson, P. R. (2016). Core Outcome Set–STAndards for Reporting: The COS-STAR Statement. PLoS Medicine, 13(10). doi:10.1371/journal.pmed.1002148

DOI
10.1371/journal.pmed.1002148
Journal article

PAEDIATRIC ADVERSE DRUG REACTIONS (ADRS): A COMPARISON OF A NEWLY DEVELOPED AVOIDABILITY TOOL TO EXISTING HALLAS ASSESSMENTS.

Bracken, L., Kirkham, J., Nunn, A., Pirmohamed, M., Peak, M., & Turner, M. (2016). PAEDIATRIC ADVERSE DRUG REACTIONS (ADRS): A COMPARISON OF A NEWLY DEVELOPED AVOIDABILITY TOOL TO EXISTING HALLAS ASSESSMENTS.. Poster session presented at the meeting of Unknown Conference. doi:10.1136/archdischild-2016-311535.72

DOI
10.1136/archdischild-2016-311535.72
Poster

How Much Participant Outcome Data Is Missing from Sight: Findings from a Cohort of Trials Submitted to a German Research Ethics Committee

Kirkham, J. J., Dwan, K. M., Bluemle, A., von Elm, E., & Williamson, P. R. (2016). How Much Participant Outcome Data Is Missing from Sight: Findings from a Cohort of Trials Submitted to a German Research Ethics Committee. PLOS ONE, 11(6). doi:10.1371/journal.pone.0157883

DOI
10.1371/journal.pone.0157883
Journal article

Feasibility study to examine discrepancy rates in prespecified and reported outcomes in articles submitted to The BMJ

Weston, J., Dwan, K., Altman, D., Clarke, M., Gamble, C., Schroter, S., . . . Kirkham, J. J. (2016). Feasibility study to examine discrepancy rates in prespecified and reported outcomes in articles submitted to The BMJ. BMJ Open, 6(4). doi:10.1136/bmjopen-2015-010075

DOI
10.1136/bmjopen-2015-010075
Journal article

Referral patterns after a seizure admission in an English region: an opportunity for effective intervention? An observational study of routine hospital data

Grainger, R., Pearson, M., Dixon, P., Devonport, E., Timoney, M., Bodger, K., . . . Marson, A. (2016). Referral patterns after a seizure admission in an English region: an opportunity for effective intervention? An observational study of routine hospital data. BMJ OPEN, 6(1). doi:10.1136/bmjopen-2015-010100

DOI
10.1136/bmjopen-2015-010100
Journal article

2015

Citation analysis: a new approach to assess the uptake of core outcome sets

Barnes, K., Clarke, M., Kirkham, J., & Williamson, P. (2015). Citation analysis: a new approach to assess the uptake of core outcome sets. In TRIALS Vol. 16. doi:10.1186/1745-6215-16-S2-P50

DOI
10.1186/1745-6215-16-S2-P50
Conference Paper

Selective reporting in clinical trials - an examination of discrepancy rates in pre-specified and reported outcomes in articles submitted to the BMJ

Weston, J., Dwan, K., Altman, D., Clarke, M., Gamble, C., Groves, T., . . . Kirkham, J. (2015). Selective reporting in clinical trials - an examination of discrepancy rates in pre-specified and reported outcomes in articles submitted to the BMJ. In TRIALS Vol. 16. doi:10.1186/1745-6215-16-S2-O72

DOI
10.1186/1745-6215-16-S2-O72
Conference Paper

A pilot randomised controlled trial to assess the utility of an e-learning package that trains users in adverse drug reaction causality.

Conroy, E., Kirkham, J., Bellis, J., Peak, M., Smyth, R., Williamson, P., & Pirmohamed, M. (2015). A pilot randomised controlled trial to assess the utility of an e-learning package that trains users in adverse drug reaction causality.. The International Journal of Pharmacy Practice, 23(6), 447-455. doi:10.1111/ijpp.12197

DOI
10.1111/ijpp.12197
Journal article

Development of interferon beta-neutralising antibodies in multiple sclerosis-a systematic review and meta-analysis

Govindappa, K., Sathish, J., Park, K., Kirkham, J., & Pirmohamed, M. (2015). Development of interferon beta-neutralising antibodies in multiple sclerosis-a systematic review and meta-analysis. EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY, 71(11), 1287-1298. doi:10.1007/s00228-015-1921-0

DOI
10.1007/s00228-015-1921-0
Journal article

Development of processes allowing near real-time refinement and validation of triage tools during the early stage of an outbreak in readiness for surge: the FLU-CATs Study

Venkatesan, S., Myles, P. R., McCann, G., Kousoulis, A. A., Hashmi, M., Belatri, R., . . . Semple, M. G. (2015). Development of processes allowing near real-time refinement and validation of triage tools during the early stage of an outbreak in readiness for surge: the FLU-CATs Study. Health Technology Assessment, 19(89), 1-132. doi:10.3310/hta19890

DOI
10.3310/hta19890
Journal article

The management of Otitis Media with Effusion in children with cleft palate (mOMEnt): a feasibility study and economic evaluation

Bruce, I., Harman, N., Williamson, P., Tierney, S., Callery, P., Mohiuddin, S., . . . O'Brien, K. (2015). The management of Otitis Media with Effusion in children with cleft palate (mOMEnt): a feasibility study and economic evaluation. HEALTH TECHNOLOGY ASSESSMENT, 19(68), 1-+. doi:10.3310/hta19680

DOI
10.3310/hta19680
Journal article

The Importance of Integration of Stakeholder Views in Core Outcome Set Development: Otitis Media with Effusion in Children with Cleft Palate

Harman, N. L., Bruce, I. A., Kirkham, J. J., Tierney, S., Callery, P., O'Brien, K., . . . Williamson, P. R. (2015). The Importance of Integration of Stakeholder Views in Core Outcome Set Development: Otitis Media with Effusion in Children with Cleft Palate. PLOS ONE, 10(6). doi:10.1371/journal.pone.0129514

DOI
10.1371/journal.pone.0129514
Journal article

Development of an internationally agreed minimal dataset for juvenile dermatomyositis (JDM) for clinical and research use

McCann, L. J., Kirkham, J. J., Wedderburn, L. R., Pilkington, C., Huber, A. M., Ravelli, A., . . . Beresford, M. W. (2015). Development of an internationally agreed minimal dataset for juvenile dermatomyositis (JDM) for clinical and research use. TRIALS, 16. doi:10.1186/s13063-015-0784-0

DOI
10.1186/s13063-015-0784-0
Journal article

DEVELOPMENT OF AN INTERNATIONALLY AGREED MINIMAL DATASET FOR JUVENILE DERMATOMYOSITIS (JDM) FOR CLINICAL AND RESEARCH USE

McCann, L., Wedderburn, L. R., Pilkington, C., Huber, A. M., Ravelli, A., Williamson, P., . . . Beresford, M. W. (2015). DEVELOPMENT OF AN INTERNATIONALLY AGREED MINIMAL DATASET FOR JUVENILE DERMATOMYOSITIS (JDM) FOR CLINICAL AND RESEARCH USE. In ANNALS OF THE RHEUMATIC DISEASES Vol. 74 (pp. 837-838). doi:10.1136/annrheumdis-2015-eular.2479

DOI
10.1136/annrheumdis-2015-eular.2479
Conference Paper

Multivariate meta-analysis helps examine the impact of outcome reporting bias in Cochrane rheumatoid arthritis reviews

Frosi, G., Riley, R. D., Williamson, P. R., & Kirkham, J. J. (2015). Multivariate meta-analysis helps examine the impact of outcome reporting bias in Cochrane rheumatoid arthritis reviews. JOURNAL OF CLINICAL EPIDEMIOLOGY, 68(5), 542-550. doi:10.1016/j.jclinepi.2014.11.017

DOI
10.1016/j.jclinepi.2014.11.017
Journal article

National Audit of Seizure management In Hospitals (NASH): results of the national audit of adult epilepsy in the UK

Dixon, P. A., Kirkham, J. J., Marson, A. G., & Pearson, M. G. (2015). National Audit of Seizure management In Hospitals (NASH): results of the national audit of adult epilepsy in the UK. BMJ OPEN, 5(3). doi:10.1136/bmjopen-2014-007325

DOI
10.1136/bmjopen-2014-007325
Journal article

Development of an Internationally Agreed Minimal Dataset for Juvenile Dermatomyositis (JDM) for Clinical and Research Use

McCann, L. J., Wedderburn, L. R., Pilkington, C., Huber, A. M., Ravelli, A., Kirkham, J., . . . Beresford, M. W. (2015). Development of an Internationally Agreed Minimal Dataset for Juvenile Dermatomyositis (JDM) for Clinical and Research Use. ARTHRITIS & RHEUMATOLOGY, 67. Retrieved from https://www.webofscience.com/

Journal article

2014

Clinical coding of prospectively identified paediatric adverse drug reactions – a retrospective review of patient records

Bellis, J. R., Kirkham, J. J., Nunn, A. J., & Pirmohamed, M. (2014). Clinical coding of prospectively identified paediatric adverse drug reactions – a retrospective review of patient records. BMC PHARMACOLOGY & TOXICOLOGY, 15. doi:10.1186/2050-6511-15-72

DOI
10.1186/2050-6511-15-72
Journal article

Bias due to selective inclusion and reporting of outcomes and analyses in systematic reviews of randomised trials of healthcare interventions

Page, M. J., McKenzie, J. E., Kirkham, J., Dwan, K., Kramer, S., Green, S., & Forbes, A. (2014). Bias due to selective inclusion and reporting of outcomes and analyses in systematic reviews of randomised trials of healthcare interventions. Cochrane Database of Systematic Reviews. doi:10.1002/14651858.MR000035.pub2

DOI
10.1002/14651858.MR000035.pub2
Journal article

Dexamethasone and haemorrhage risk in paediatric tonsillectomy: a systematic review and meta-analysis

Bellis, J., Pirmohamed, M., Nunn, A. J., Loke, Y. K., De, S., Golder, S., & Kirkham, J. J. (2014). Dexamethasone and haemorrhage risk in paediatric tonsillectomy: a systematic review and meta-analysis. British Journal of Anaesthesia, 113(1), 23-42. doi:10.1093/bja/aeu152

DOI
10.1093/bja/aeu152
Journal article

A review of the handling of missing longitudinal outcome data in clinical trials

Powney, M., Williamson, P., Kirkham, J., & Kolamunnage-Dona, R. (2014). A review of the handling of missing longitudinal outcome data in clinical trials. Trials, 15. doi:10.1186/1745-6215-15-237

DOI
10.1186/1745-6215-15-237
Journal article

Exploring perceived barriers, drivers, impacts and the need for evaluation of public involvement in health and social care research: a modified Delphi study

Snape, D., Kirkham, J., Britten, N., Froggatt, K., Gradinger, F., Lobban, F., . . . Jacoby, A. (2014). Exploring perceived barriers, drivers, impacts and the need for evaluation of public involvement in health and social care research: a modified Delphi study. BMJ OPEN, 4(6). doi:10.1136/bmjopen-2014-004943

DOI
10.1136/bmjopen-2014-004943
Journal article

A model-based correction for outcome reporting bias in meta-analysis

Copas, J., Dwan, K., Kirkham, J., & Williamson, P. (2014). A model-based correction for outcome reporting bias in meta-analysis. BIOSTATISTICS, 15(2), 370-383. doi:10.1093/biostatistics/kxt046

DOI
10.1093/biostatistics/kxt046
Journal article

Adverse drug reactions and off-label and unlicensed medicines in children: a prospective cohort study of unplanned admissions to a paediatric hospital

Bellis, J. R., Kirkham, J. J., Nunn, A. J., & Pirmohamed, M. (2014). Adverse drug reactions and off-label and unlicensed medicines in children: a prospective cohort study of unplanned admissions to a paediatric hospital. British Journal of Clinical Pharmacology, 77(3), 545-553. doi:10.1111/bcp.12222

DOI
10.1111/bcp.12222
Journal article

Exploring areas of consensus and conflict around values underpinning public involvement in health and social care research: a modified Delphi study

Snape, D., Kirkham, J., Preston, J., Popay, J., Britten, N., Collins, M., . . . Jacoby, A. (2014). Exploring areas of consensus and conflict around values underpinning public involvement in health and social care research: a modified Delphi study. BMJ OPEN, 4(1). doi:10.1136/bmjopen-2013-004217

DOI
10.1136/bmjopen-2013-004217
Journal article

Evidence for the selective reporting of analyses and discrepancies in clinical trials: a systematic review of cohort studies of clinical trials

Dwan, K., Altman, D. G., Clarke, M., Gamble, C., Higgins, J. P. T., Sterne, J. A. C., . . . Kirkham, J. J. (2014). Evidence for the selective reporting of analyses and discrepancies in clinical trials: a systematic review of cohort studies of clinical trials. PLoS Medicine, 11(6). doi:10.1371/journal.pmed.1001666

DOI
10.1371/journal.pmed.1001666
Journal article

How well are the ASAS/OMERACT Core Outcome Sets for Ankylosing Spondylitis implemented in randomized clinical trials? A systematic literature review

Bautista-Molano, W., Navarro-Compan, V., Landewe, R. B. M., Boers, M., Kirkham, J. J., & van der Heijde, D. (2014). How well are the ASAS/OMERACT Core Outcome Sets for Ankylosing Spondylitis implemented in randomized clinical trials? A systematic literature review. CLINICAL RHEUMATOLOGY, 33(9), 1313-1322. doi:10.1007/s10067-014-2728-6

DOI
10.1007/s10067-014-2728-6
Journal article

2013

Adverse drug reactions and off-label and unlicensed medicines in children: a nested case-control study of inpatients in a pediatric hospital

Bellis, J. R., Kirkham, J. J., Thiesen, S., Conroy, E. J., Bracken, L. E., Mannix, H. L., . . . Pirmohamed, M. (2013). Adverse drug reactions and off-label and unlicensed medicines in children: a nested case-control study of inpatients in a pediatric hospital. BMC MEDICINE, 11. doi:10.1186/1741-7015-11-238

DOI
10.1186/1741-7015-11-238
Journal article

Incidence, characteristics and risk factors of adverse drug reactions in hospitalized children - a prospective observational cohort study of 6,601 admissions

Thiesen, S., Conroy, E. J., Bellis, J. R., Bracken, L. E., Mannix, H. L., Bird, K. A., . . . Smyth, R. L. (2013). Incidence, characteristics and risk factors of adverse drug reactions in hospitalized children - a prospective observational cohort study of 6,601 admissions. BMC MEDICINE, 11. doi:10.1186/1741-7015-11-237

DOI
10.1186/1741-7015-11-237
Journal article

Selective reporting of outcomes in randomised controlled trials in systematic reviews of cystic fibrosis

Dwan, K., Kirkham, J. J., Williamson, P. R., & Gamble, C. (2013). Selective reporting of outcomes in randomised controlled trials in systematic reviews of cystic fibrosis. BMJ OPEN, 3(6). doi:10.1136/bmjopen-2013-002709

DOI
10.1136/bmjopen-2013-002709
Journal article

Can a core outcome set improve the quality of systematic reviews? - a survey of the Co-ordinating Editors of Cochrane review groups

Kirkham, J. J., Gargon, E., Clarke, M., & Williamson, P. R. (2013). Can a core outcome set improve the quality of systematic reviews? - a survey of the Co-ordinating Editors of Cochrane review groups. TRIALS, 14. doi:10.1186/1745-6215-14-21

DOI
10.1186/1745-6215-14-21
Journal article

Cross-sectional study of prescribing errors in patients admitted to nine hospitals across North West England

Seden, K., Kirkham, J. J., Kennedy, T., Lloyd, M., James, S., Mcmanus, A., . . . Khoo, S. H. (2013). Cross-sectional study of prescribing errors in patients admitted to nine hospitals across North West England. BMJ OPEN, 3(1). doi:10.1136/bmjopen-2012-002036

DOI
10.1136/bmjopen-2012-002036
Journal article

Systematic Review of the Selective Reporting of Analyses

Dwan, K., Gable, C., Williamson, P. R., Higgins, J. P., Sterne, J. A., Altman, D. G., . . . Kirkham, J. J. (2013). Systematic Review of the Selective Reporting of Analyses. In Peer Review Congress (pp. 1). Chicago: BMJ.

Conference Paper

Systematic Review of the Selective Reporting of Analyses

Dwan, K., Gamble, C., Williamson, P. R., Higgins, J. P. T., Sterne, J. A. C., Altman, D. G., . . . Kirkham, J. J. (2013). Systematic Review of the Selective Reporting of Analyses. In The Cochrane Colloquium (pp. 1). Quebec City: Wiley-Blackwell.

Conference Paper

2012

The Reporting of Harms in Randomized Controlled Trials of Hypertension Using the CONSORT Criteria for Harm Reporting

Bagul, N. B., & Kirkham, J. J. (2012). The Reporting of Harms in Randomized Controlled Trials of Hypertension Using the CONSORT Criteria for Harm Reporting. CLINICAL AND EXPERIMENTAL HYPERTENSION, 34(8), 548-554. doi:10.3109/10641963.2012.681724

DOI
10.3109/10641963.2012.681724
Journal article

Adverse Drug Reactions Causing Admission to a Paediatric Hospital

Gallagher, R. M., Mason, J. R., Bird, K. A., Kirkham, J. J., Peak, M., Williamson, P. R., . . . Smyth, R. L. (2012). Adverse Drug Reactions Causing Admission to a Paediatric Hospital. PLOS ONE, 7(12). doi:10.1371/journal.pone.0050127

DOI
10.1371/journal.pone.0050127
Journal article

NATIONAL AUDIT OF SEIZURE MANAGEMENT IN HOSPITALS: INITIAL FINDINGS

Marson, T., Pearson, M. G., Kirkham, J. J., Dixon, P. A., & Billington, K. (2012). NATIONAL AUDIT OF SEIZURE MANAGEMENT IN HOSPITALS: INITIAL FINDINGS. In JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY Vol. 83. doi:10.1136/jnnp-2012-304200a.134

DOI
10.1136/jnnp-2012-304200a.134
Conference Paper

A multivariate meta-analysis approach for reducing the impact of outcome reporting bias in systematic reviews

Kirkham, J. J., Riley, R. D., & Williamson, P. R. (2012). A multivariate meta-analysis approach for reducing the impact of outcome reporting bias in systematic reviews. STATISTICS IN MEDICINE, 31(20), 2179-2195. doi:10.1002/sim.5356

DOI
10.1002/sim.5356
Journal article

Adverse Drug Reactions in Children-A Systematic Review

Smyth, R. M. D., Gargon, E., Kirkham, J., Cresswell, L., Golder, S., Smyth, R., & Williamson, P. (2012). Adverse Drug Reactions in Children-A Systematic Review. PLOS ONE, 7(3). doi:10.1371/journal.pone.0024061

DOI
10.1371/journal.pone.0024061
Journal article

Bias due to selective inclusion and reporting of outcomes and analyses in systematic reviews of randomised trials of healthcare interventions

Page, M. J., McKenzie, J. E., Dwan, K., Kirkham, J., Green, S., & Forbes, A. (2012). Bias due to selective inclusion and reporting of outcomes and analyses in systematic reviews of randomised trials of healthcare interventions. doi:10.1002/14651858.mr000035

DOI
10.1002/14651858.mr000035
Journal article

NATIONAL AUDIT OF SEIZURE MANAGEMENT IN HOSPITALS: INITIAL FINDINGS

Marson, A. G., Dixon, P., Pearson, M., Kirkham, J., & Billington, K. (2012). NATIONAL AUDIT OF SEIZURE MANAGEMENT IN HOSPITALS: INITIAL FINDINGS. In EPILEPSIA Vol. 53 (pp. 73). Retrieved from https://www.webofscience.com/

Conference Paper

2011

Development and Inter-Rater Reliability of the Liverpool Adverse Drug Reaction Causality Assessment Tool

Gallagher, R. M., Kirkham, J. J., Mason, J. R., Bird, K. A., Williamson, P. R., Nunn, A. J., . . . Pirmohamed, M. (2011). Development and Inter-Rater Reliability of the Liverpool Adverse Drug Reaction Causality Assessment Tool. PLOS ONE, 6(12). doi:10.1371/journal.pone.0028096

DOI
10.1371/journal.pone.0028096
Journal article

Frequency and reasons for outcome reporting bias in clinical trials: interviews with trialists

Smyth, R. M. D., Kirkham, J. J., Jacoby, A., Altman, D. G., Gamble, C., & Williamson, P. R. (2011). Frequency and reasons for outcome reporting bias in clinical trials: interviews with trialists. BMJ-BRITISH MEDICAL JOURNAL, 342. doi:10.1136/bmj.c7153

DOI
10.1136/bmj.c7153
Journal article

2010

Bias Due to Changes in Specified Outcomes during the Systematic Review Process

Kirkham, J. J., Altman, D. G., & Williamson, P. R. (2010). Bias Due to Changes in Specified Outcomes during the Systematic Review Process. In PLOS ONE Vol. 5. doi:10.1371/journal.pone.0009810

DOI
10.1371/journal.pone.0009810
Conference Paper

Selective outcome reporting: telling and detecting true lies. The state of the science

Macura, A., Abraha, I., Kirkham, J., Gensini, G. F., Moja, L., & Iorio, A. (2010). Selective outcome reporting: telling and detecting true lies. The state of the science. INTERNAL AND EMERGENCY MEDICINE, 5(2), 151-155. doi:10.1007/s11739-010-0371-z

DOI
10.1007/s11739-010-0371-z
Journal article

The impact of outcome reporting bias in randomised controlled trials on a cohort of systematic reviews

Kirkham, J. J., Dwan, K. M., Altman, D. G., Gamble, C., Dodd, S., Smyth, R., & Williamson, P. R. (2010). The impact of outcome reporting bias in randomised controlled trials on a cohort of systematic reviews. BMJ-BRITISH MEDICAL JOURNAL, 340. doi:10.1136/bmj.c365

DOI
10.1136/bmj.c365
Journal article

Abstracts of the 2010 Joint Colloquium of The Cochrane and Campbell Collaborations

Abstracts of the 2010 Joint Colloquium of The Cochrane and Campbell Collaborations (2010). In Abstracts of the 2010 Joint Colloquium of The Cochrane and Campbell Collaborations. Wiley. doi:10.1002/14651858.cd000002

DOI
10.1002/14651858.cd000002
Conference Paper

2009

Deferasirox for the treatment of iron overload associated with regular blood transfusions (transfusional haemosiderosis) in patients suffering with chronic anaemia: a systematic review and economic evaluation

McLeod, C., Fleeman, N., Kirkham, J., Bagust, A., Boland, A., Chu, P., . . . Walley, T. (2009). Deferasirox for the treatment of iron overload associated with regular blood transfusions (transfusional haemosiderosis) in patients suffering with chronic anaemia: a systematic review and economic evaluation. HEALTH TECHNOLOGY ASSESSMENT, 13(1), 1-+. doi:10.3310/hta13010

DOI
10.3310/hta13010
Journal article

2008

The Use of Statistical Process Control for Monitoring Institutional Performance in Trauma Care

Kirkham, J. J., & Bouamra, O. (2008). The Use of Statistical Process Control for Monitoring Institutional Performance in Trauma Care. JOURNAL OF TRAUMA-INJURY INFECTION AND CRITICAL CARE, 65(6), 1494-1501. doi:10.1097/TA.0b013e31815ebabf

DOI
10.1097/TA.0b013e31815ebabf
Journal article

A comparison of hospital performance with non-ignorable missing covariates: An application to trauma care data

Kirkham, J. J. (2008). A comparison of hospital performance with non-ignorable missing covariates: An application to trauma care data. STATISTICS IN MEDICINE, 27(27), 5725-5744. doi:10.1002/sim.3379

DOI
10.1002/sim.3379
Journal article

The prevalence of outcome reporting bias in trials (the ORBIT study)

Kirkham, J. J., Altman, D., Dodd, S., Dwan, K., Gamble, C., Jacoby, A., . . . Williamson, P. R. (2008). The prevalence of outcome reporting bias in trials (the ORBIT study). In 16th Cochrane Colloquium (pp. 14-53). Freiberg: John Wiley.

Conference Paper

2006

Statistical Analysis of Trauma Care Data

Kirkham, J. J. (2006). Statistical Analysis of Trauma Care Data. (PhD Thesis, Lancaster University).

Thesis / Dissertation

2005

The patterning of hypodontia in a group of young adults in Sheffield, UK

Kirkham, J., Kaur, R., Stillman, E. C., Blackwell, P. G., Elcock, C., & Brook, A. H. (2005). The patterning of hypodontia in a group of young adults in Sheffield, UK. ARCHIVES OF ORAL BIOLOGY, 50(2), 287-291. doi:10.1016/j.archoralbio.2004.11.015

DOI
10.1016/j.archoralbio.2004.11.015
Journal article

2003

The patterning of hypodontia in a group of young adults in Sheffield, UK

Kirkham, J. J. (2003). The patterning of hypodontia in a group of young adults in Sheffield, UK. (Master's Thesis, The University of Sheffield).

Thesis / Dissertation