Early-life trajectories of poor physical and mental health shape adult health and wellbeing, and influence societal productivity. Moreover, the role of biological sex in determining health outcomes, particularly in non-communicable diseases, is under-studied and poorly understood. Identifying the drivers of ill health and tackling the life expectancy gap between the richest and poorest in our society will not only improve quality of life, but also have significant economic benefits relating to wealth and productivity.
Key aims
Identify the early life factors which reduce healthy lifespan
A healthy start in life is essential to a healthy lifespan, but we still still don't understand precisely which factors in early life are major determinants of lifelong well-being. Our research focuses on both early life determinants, and the role of biological sex in determining adult disease.
Address complex diseases of later life
As we age, we are more likely to develop major diseases which have an impact on healthspan. Having more than one long term health condition not only shortens healthspan but places a significant burden on individuals, care-providers, as well as the NHS. We're building on our expertise to effectively treat and/or prevent disorders that are significant causes of ill-health in middle and later life.
Reduce health inequalities
We're unpicking the pathways that lead to inequalities across the life course. By understanding the major psychological, behavioural, environmental, social, situational and biological challenges faced by societies and individuals, we aim to reveal how they contribute to poor ageing and premature mortality.
