Selected Publications

• García-Fiñana M, Hughes DM, Cheyne CP, Burnside G, Stockbridge M, Fowler TA et al. (2021) Performance of the Innova SARS-CoV-2 antigen rapid lateral flow test in the Liverpool asymptomatic testing pilot: population based cohort study BMJ, 374:n1637 doi:10.1136/bmj.n1637 * denotes joint first author
• García-Fiñana M, Buchan IE. (2021) Rapid antigen testing in COVID-19 responses. Science, 372:571-2.doi:10.1126/science.abi6680 pmid:33958462.
• Hughes DM, García-Fiñana M & Wand MP. (2021). Fast approximate inference for multivariate longitudinal data. Biostatistics. Doi:10.1093/biostatistics/kxab021
• Cheyne CP, Burgess PI, Broadbent DM, García-Fiñana M, Stratton IM, Criddle T., . . . Grp, I. S. D. R. S. (2021). Incidence of sight-threatening diabetic retinopathy in an established urban screening programme: An 11-year cohort study. Diabetic Medicine, 38(9). doi:10.1111/dme.14583
• Hughes DM, Cheyne CP, Burnside G, Dodd S, Turtle L, García-Fiñana M, Semple MG. Independent analysis on recent hospital case fatality and variant of concern VOC2020-01 using CO-CIN data (2021). Scientific Advisory Group for Emergencies (SAGE) . https://www.gov.uk/government/publications/independent-analysis-on-recent-hospital-case-fatality-and-variant-of-concern-voc2020-01-using-co-cin-data-20-january-2021
• Hughes D, Berhane S, de Groot E, …, García-Fiñana M, Johnson P (2021). Serum levels of Alpha Fetoprotein Increase More Than 10 Years Before Detection of Hepatocellular Carcinoma. Clinical Gastroenterology and Hepatology. 19 (1): 162-170.e4. 
• Mina MJ, Peto TE, García-Fiñana M, Semple MG, Buchan IE. (2021) Clarifying the evidence on SARS-CoV-2 antigen rapid tests in public health responses to COVID-19. Lancet, 397(10283), 1425-1427. 
• Docherty A,  Mulholland, RH, Lone NI, Cheyne CP, De Angelis D, Mulholland R  … García-Fiñana, M  … Hughes DM … Semple M. (2021). Changes in UK hospital mortality in the first wave of COVID-19: the ISARIC WHO Clinical Characterisation Protocol prospective multicentre observational cohort study. Lancet Infectious diseases 10.1101/2020.12.19.20248559.
• El Saeiti R, García-Fiñana M, & Hughes DM. (2021). The effect of random-effects misspecification on classification accuracy. The international journal of biostatistics. doi:10.1515/ijb-2019-0159
• Green MA, García-Fiñana M, Barr B, Burnside G, Cheyne CP, Hughes DM, Ashton M, Sheard S, Buchan, I. (2021) Evaluating social and spatial inequalities of large scale rapid lateral flow SARS-CoV-2 antigen testing in COVID-19 management: An observational study of Liverpool, UK (November 2020 to January 2021). Lancet Reg Health Eur2021;6:100107. doi:10.1016/j.lanepe.2021.100107 pmid:34002172
• Tulloch JSP, Micocci M, Buckle P, Lawrenson K, Kierkegaard P. . García-Fiñana M. . Parvulescu P (2021). Enhanced lateral flow testing strategies in care homes are associated with poor adherence and were insufficient to prevent COVID-19 outbreaks: Results from a mixed methods implementation study. Age and ageing. doi:10.1093/ageing/afab162
• Zhao S, Maglio C, Hughes DM, Cook J. (2021) Body fat composition and risk of rheumatoid arthritis. Arthritis and Rheumatology, in press
• Frau A, Lett L, Slater R, Young GR, Berrington J, Hughes DM, Embleton N, Probert C. (2021) The stool volatile metabolome of pre-term babies. Metabolites, in press
• Zhao S, Jones G, Macfarlane G, Hughes D, Moots R & Goodson N. Association between comorbidities and disease activity in axial spondyloarthritis: results from the BSRBR-AS. Rheumatology, in press
• Zhao, SS, Jones G, Hughes DM, Moots R, & Goodson N. (2021) Depression and anxiety symptoms at TNF inhibitor initiation are associated with impaired treatment response in axial spondyloarthritis. Rheumatology, in press
• Zhao SS, Jones GT, Macfarlane GJ, Hughes DM, Moots RJ, Goodson NJ. (2020) Comorbidity and response to TNF inhibitors in axial spondyloarthritis: longitudinal analysis of the BSRBR-AS (Rheumatology, in press) 
• García-Fiñana M, Hughes DM, Cheyne CP, et al. Innova Lateral Flow SARS-CoV-2 Antigen test accuracy in Liverpool Pilot: preliminary data, 26 November 2020. Scientific Advisory Group for Emergencies (SAGE) 2020. https://www.gov.uk/government/publications/innova-lateral-flow-sars-cov-2-antigen-test-accuracy-in-liverpool-pilot-preliminary-data-26-november-2020
• Alsefri M, Sudell M, García-Fiñana M, Kolamunnage-Dona R (2020). Bayesian joint modelling of longitudinal and time to event data: a methodological review. BMC Medical Research Methodology. 10.1186/s12874-020-00976-2
• Probert, C., Greenwood, R., Mayor, A., Hughes, … García-Fiñana M, Ewer, A. K. (2020). Faecal volatile organic compounds in preterm babies at risk of necrotising enterocolitis: the DOVE study. Archives of disease in childhood. 105(5): 474-479. http://dx.doi.org/10.1136/archdischild-2019-318221
• Pushpakom S, Kolamunnage-Dona R, Taylor C, Foster T, Spowart C, García-Fiñana M., … Pirmohamed M.  TAILoR Study Group. (2020). TAILoR (TelmisArtan and InsuLin Resistance in Human Immunodeficiency Virus [HIV]): An Adaptive-design, Dose-ranging Phase IIb Randomized Trial of Telmisartan for the Reduction of Insulin Resistance in HIV-positive Individuals on Combination Antiretroviral Therapy. Clinical infectious diseases: an official publication of the Infectious Diseases Society of America. 70(10):2062-2072. doi:10.1093/cid/ciz589
• Han G, Berhane S, Toyoda H, Bettinger D, Elshaarawy O, Chan AWH, … García-Fiñana M … Johnson PJ (2020). Prediction of Survival Among Patients Receiving Transarterial Chemoembolization for Hepatocellular Carcinoma: A Response-Based Approach. Hepatology. 72(1): 198-212. doi: 10.1002/hep.31022
• Zakaria R, Chen YJ, Hughes DM, Wang S, Chawla S, Poptani H, Berghoff AS, Preusser M, Jenkinson MD, Mohan S. (2020) Does the application of diffusion weighted imaging improve the prediction of survival in patients with resected brain metastases? A retrospective multicentre study. Cancer Imaging, 20(1) 16.
• Bradley P, Frost F, Tharmaratnam K, Wootton DG, et al. (2020) Utility of established prognostic scores in COVID-19 hospital admissions: multicentre prospective evaluation of CURB-65, NEWS2 and qSOFA. BMJ Open Resp Res; 7:e000729. doi:10.1136/bmjresp-2020-000729
• Smith BL, Hughes DM, Badu-Tawiah AK, Eccles R, Goodall I, Maher S. (2019) Rapid Scotch Whisky Analysis and Authentication using Desorption Atmospheric Pressure Chemical Ionisation Mass Spectrometry. Scientific Reports, 9(1) 7994
• García-Fiñana M, Hughes DM, Cheyne CP, Broadbent DM, Wang A, Komárek A, Stratton IM, Mobayen-Rahni M, Alshukri A, Vora JP, Harding SP (2019). Personalized risk-based screening for diabetic retinopathy: a multivariate approach vs. the use of stratification rules. Diabetes, Obesity and Metabolism, 21(3):560-568.
• Probert, C., Greenwood, R., Mayor, A., Hughes, D., Aggio, R., Jackson, R. E., . . . Ewer, A. K. (2019). Faecal volatile organic compounds in preterm babies at risk of necrotising enterocolitis: the DOVE study.Archives of disease in childhood. http://dx.doi.org/10.1136/archdischild-2019-318221
• Hughes DM, Bonnett LB, Marson AG, García-Fiñana M (2019). Identifying patients who will not re-achieve remission after breakthrough seizures.Epilepsia, 60(4), 774-782.
• Zhao, S. S., Macfarlane, G. J., Jones, G. T., Gaffney, K., Hughes, D. M., Moots, R. J., & Goodson, N. J. (2019). Smoking does not protect patients with axial spondyloarthritis from attacks of uveitis. Annals of the rheumatic diseases, 78(9) http://dx.doi.org/10.1136/annrheumdis-2019-215348
• Berhane S, Fox R, García-Fiñana M, Cucchetti A, Johnson P (2019). Using prognostic and predictive clinical features to make personalised survival prediction in advanced hepatocellular carcinoma patients undergoing sorafenib treatment, British Journal of Cancer 121(2):117-124.
• Zhao, S. S., Yoshida, K., Jones, G. T., Hughes, D. M., Duffield, S. J., Tedeschi, S. K., . . . Goodson, N. J. (2019). Smoking status and cause-specific discontinuation of tumour necrosis factor inhibitors in axial spondyloarthritis. Arthritis Research & Therapy, 21
• Zhao, S. S., Radner, H., Siebert, S., Duffield, S. J., Thong, D., Hughes, D. M., . . . Goodson, N. J. (2019). Comorbidity burden in axial spondyloarthritis: a cluster analysis. Rheumatology, 58(10)
• Broadbent DM, Sampson CJ, Wang A, Howard L, … García-Fiñana M, Stratton IM, James M, Harding SP; ISDR Study Group (2019). Individualised screening for diabetic retinopathy: the ISDR study-rationale, design and methodology for a randomised controlled trial comparing annual and individualised risk-based variable-interval screening. BMJ Open. doi: 10.1136/bmjopen-2018-025788   
• Pushpakom S, Kolamunnage-Dona R, Taylor C, Foster T, Spowart C, García-Fiñana M., . . . TAILoR Study Group. (2019). TAILoR (TelmisArtan and InsuLin Resistance in Human Immunodeficiency Virus [HIV]): An Adaptive-design, Dose-ranging Phase IIb Randomized Trial of Telmisartan for the Reduction of Insulin Resistance in HIV-positive Individuals on Combination Antiretroviral Therapy. Clinical infectious diseases: an official publication of the Infectious Diseases Society of America. doi:10.1093/cid/ciz589
• Chan A, Zhong J, Berhane S, …, García-Fiñana M, Kudo M, Kumada T; Roayaie S, Johnson PJ (2018). Prediction of Early Recurrence after Surgical Resection of Hepatocellular Carcinoma: An International Collaborative Study. Journal of Hepatology.DOI: 10.1016/j. jhep.2018 .08.027 
• Hughes DM, Bonnett LB, Czanner G, Komárek A, Marson AG, García-Fiñana M. (2018) Identification of patients who will not achieve seizure remission within 5 years on AEDs. Neurology(accepted)
• Lythgoe DT, García-Fiñana M, Cox TF. (2018) Latent class modeling with a time-to-event distal outcome: A comparison of one, two and three-step approaches. Structural Equation Modeling:A Multidisciplinary Journal, 26(1):51-65    .
• Hughes D, Komarek A, Czanner G, García-Fiñana M. (2018) Dynamic longitudinal discriminant analysis using multiple longitudinal markers of different types. Statistical Methods in Medical Research.27(7):2060-2080.
• Hughes D, Komarek A, Bonnett L., Czanner G, García-Fiñana M. (2017) Dynamic prediction using credible intervals in longitudinal discriminant analysis. Statistics in Medicine.36(24): 3858–3874.
• Burgess P, Harding SP, García-Fiñana M, Beare NAV, Glover S, Cohen DB, MSukwa G, TJ Allain. (2017) Incidence and Progression of Diabetic Retinopathy in Sub-Saharan Africa: a Five Year Cohort Study. PLOS onehttps://doi.org/10.1371/journal.pone.0181359.
• Hughes D, El Saeiti R, García-Fiñana, M. (2017) A comparison of group prediction approaches in longitudinal discriminant analysis. Biometrical Journal: Journal of Mathematical Methods in Biosciences.1002/bimj.201700013.
• Eleuteri A, Fisher AC, Broadbent DM, García-Fiñana M, Cheyne CP, Wang A, Stratton IM, Gabbay M, Seddon DS, Harding SP for the ISDR Study Group. (2017) Individualised variable interval risk-based screening for sight threatening diabetic retinopathy – the Liverpool Risk Calculation Engine. Diabetologia. 60(11):2174-2182.
• Powell JL, Grossi D, Corcoran R, Gobet F, García-Fiñana M. (2017). The neural correlates of theory of mind and their role during empathy and the game of chess: A functional magnetic resonance imaging study. Neuroscience,355, 149-160.
• Cox T, Czanner G. A practical divergence measure for survival distributions that can be estimated from Kaplan-Meier curves. (2016) Statistics in Medicine,35(14):2406-2421
• Burgess P, Harding SP, García-Fiñana M, Beare NAV, Glover S, Cohen DB, MSukwa G, TJ Allain. (2016) First Prospective Cohort Study of Diabetic Retinopathy from Sub-Saharan Africa. Ophthalmology123(9): 1919-1925.
• Bromley R, Calderbank R, Cheyne C , Rooney C, Trayner P, Cohen MJ , Clayton-Smith J,  García-Fiñana M , Irwin B, Morrow J, Shallcross R, Baker GA. (2016) School aged cognitive abilities in children exposed to levetiracetam, topiramate or sodium valproate monotherapy. Neurology (in press)
• Baker GA, Bromley R, Briggs M, Cheyne  C , Cohen MJ , García-Fiñana  M , Gummer  A, Kneen  R , Loring DW , Mawer  GE , Meador KJ , Shallcross  R and Clayton-Smith J. (2015) IQ at 6 years following in utero exposure to antiepileptic drugs: a controlled cohort study. Neurology, 84(4):382-90.
• Scarfe L, Rak-Raszewska A, Geraci S, Darssan D, Sharkey J, Huang J, Burton NC, Mason D, Ranjzad P, Kenny S, Gretz N, Lévy R, Park BK, García-Fiñana M, Woolf AS, Murray P, Wilm B. (2015) Measures of kidney function by minimally invasive techniques correlate with histological glomerular damage in SCID mice with adriamycin-induced nephropathy. Scientific ReportsDOI:1038/srep13601  
• Powell, J, Kemp G, Dunbar R, Roberts N, Sluming V and García-Fiñana M (2014) Different association between intentionality competence and prefrontal volume in left- and right-handers. Cortex; 54: 63-73.
• Shallcross R, Bromley RL, Cheyne CP, García-Fiñana M, Irwin B, Morrow J, Baker GA. (2014) In Utero Exposure to Levetiracetam vs Valproate: Development & Language at 3 years of Age. Neurology, 82(3):213-21
• Cumberland PM, Czanner G, Bunce C, Doré CJ, García-Fiñana M. (2014) The perils of dichotomising continuous variables. BJO, 98(6):841-3
• Burgess P, Allain T, García-Fiñana M, Beare NAV, Msukwa G, Harding S. (2014) High prevalence of sight threatening retinopathy and visual impairment due to diabetes in Malawi; identification of population specific targets for intervention. Diabetic Medicine, 31(12):1643-50.