Publications
Selected publications
- Loss of FANCD2 and related proteins may predict malignant transformation in oral epithelial dysplasia (Journal article - 2022)
- Genetic variants associated with mandibular osteoradionecrosis following radiotherapy for head and neck malignancy (Journal article - 2021)
- Image fusion of IR and optical microscopy for mapping of biomolecules in tissue (Journal article - 2021)
- Analysis of head and neck carcinoma progression reveals novel and relevant stage-specific changes associated with immortalisation and malignancy (Journal article - 2019)
- SERPINE1 and SMA expression at the invasive front predict extracapsular spread and survival in oral squamous cell carcinoma (Journal article - 2014)
- The clinical determinants of malignant transformation in oral epithelial dysplasia (Journal article - 2012)
- <i>RHBDF2</i> Mutations Are Associated with Tylosis, a Familial Esophageal Cancer Syndrome (Journal article - 2012)
- TYLOSIS ESOPHAGEAL CANCER MAPPED (Journal article - 1994)
2024
An optical photothermal infrared investigation of lymph nodal metastases of oral squamous cell carcinoma.
Al Jedani, S., Lima, C., Smith, C. I., Gunning, P. J., Shaw, R. J., Barrett, S. D., . . . Weightman, P. (2024). An optical photothermal infrared investigation of lymph nodal metastases of oral squamous cell carcinoma.. Scientific reports, 14(1), 16050. doi:10.1038/s41598-024-66977-z
Prediction of prognosis in oral squamous cell carcinoma using infrared microspectroscopy.
Whitley, C. A., Ellis, B. G., Triantafyllou, A., Gunning, P. J., Gardner, P., Barrett, S. D., . . . Risk, J. M. (2024). Prediction of prognosis in oral squamous cell carcinoma using infrared microspectroscopy.. Cancer medicine, 13(5), e7094. doi:10.1002/cam4.7094
2023
Investigating iRHOM2-Associated Transcriptional Changes in Tylosis With Esophageal Cancer
Murtough, S., Babu, D., Webb, C. M., Louis dit Picard, H., McGinty, L. A., Chao-Chu, J., . . . Kelsell, D. P. (2023). Investigating iRHOM2-Associated Transcriptional Changes in Tylosis With Esophageal Cancer. Gastro Hep Advances, 3(3), 385-395. doi:10.1016/j.gastha.2023.12.007
Abstract PO-036: A deep learning alternative to regional molecular testing for HPV status
Craig, S. G., Gault, R., McCombe, K. D., Moyes, A., Sun, Y., Wang, T., . . . James, J. A. (2023). Abstract PO-036: A deep learning alternative to regional molecular testing for HPV status. In Clinical Cancer Research Vol. 29. American Association for Cancer Research (AACR). doi:10.1158/1557-3265.aacrahns23-po-036
Tissue discrimination in head and neck cancer using image fusion of IR and optical microscopy.
Al Jedani, S., Smith, C. I., Ingham, J., Whitley, C. A., Ellis, B. G., Triantafyllou, A., . . . Barrett, S. D. (2023). Tissue discrimination in head and neck cancer using image fusion of IR and optical microscopy. ANALYST, 148(17), 4189-4194. doi:10.1039/d3an00692a
Whole genome DNA methylation and mutational profiles identify novel changes in proliferative verrucous leukoplakia.
Okoturo, E., Green, D., Clarke, K., Liloglou, T., Boyd, M. T., Shaw, R. J., & Risk, J. M. (2023). Whole genome DNA methylation and mutational profiles identify novel changes in proliferative verrucous leukoplakia.. Oral surgery, oral medicine, oral pathology and oral radiology, 135(6), 893-903. doi:10.1016/j.oooo.2023.03.004
Metric-based analysis of FTIR data to discriminate tissue types in oral cancer
Ellis, B. G., Ingham, J., Whitley, C. A., Al Jedani, S., Gunning, P. J., Gardner, P., . . . Weightman, P. (2023). Metric-based analysis of FTIR data to discriminate tissue types in oral cancer. ANALYST, 148(9), 1948-1953. doi:10.1039/d3an00258f
2022
Prediction of malignant transformation in oral epithelial dysplasia using machine learning.
Ingham, J., Smith, C. I., Ellis, B. G., Whitley, C. A., Triantafyllou, A., Gunning, P. J., . . . Weightman, P. (2022). Prediction of malignant transformation in oral epithelial dysplasia using machine learning.. IOP SciNotes, 3(3), 034001. doi:10.1088/2633-1357/ac95e2
Tylosis REC virtual Site Information File
Risk, J., & Field, J. (n.d.). Tylosis REC virtual Site Information File. doi:10.17638/datacat.liverpool.ac.uk/1621
Upregulation of Cytoglobin in 3D-cultures of Head and Neck Cancer Cells: Role of Hypoxia and Implications for Cisplatin Resistance
Loss of FANCD2 and related proteins may predict malignant transformation in oral epithelial dysplasia
Ho, M. W., Ryan, M. P., Gupta, J., Triantafyllou, A., Risk, J. M., Shaw, R. J., & Wilson, J. B. (2022). Loss of FANCD2 and related proteins may predict malignant transformation in oral epithelial dysplasia. ORAL SURGERY ORAL MEDICINE ORAL PATHOLOGY ORAL RADIOLOGY, 133(4), 377-387. doi:10.1016/j.oooo.2021.07.001
Prediction of malignant transformation in oral epithelial dysplasia using infrared absorbance spectra
Ellis, B. J., Whitley, C. A., Triantafyllou, A., Gunning, P. J., Smith, C. I., Barrett, S. D., . . . Risk, J. M. (2022). Prediction of malignant transformation in oral epithelial dysplasia using infrared absorbance spectra. PLOS ONE, 17(3). doi:10.1371/journal.pone.0266043
2021
Genetic variants associated with mandibular osteoradionecrosis following radiotherapy for head and neck malignancy
Brooker, R. C., Antczak, P., Liloglou, T., Risk, J. M., Sacco, J. J., Schache, A. G., & Shaw, R. J. (2021). Genetic variants associated with mandibular osteoradionecrosis following radiotherapy for head and neck malignancy. Radiotherapy and Oncology, 165, 87-93. doi:10.1016/j.radonc.2021.10.020
Image fusion of IR and optical microscopy for mapping of biomolecules in tissue
Al Jedani, S., Whitley, C. A., Ellis, B. G., Triantafyllou, A., Smith, C. I., Gunning, P. J., . . . Barrett, S. D. (2021). Image fusion of IR and optical microscopy for mapping of biomolecules in tissue. ANALYST, 146(19), 5848-5854. doi:10.1039/d1an01161h
Insight into metastatic oral cancer tissue from novel analyses using FTIR spectroscopy and aperture IR-SNOM
Ellis, B. G., Whitley, C. A., Al Jedani, S., Smith, C. I., Gunning, P. J., Harrison, P., . . . Weightman, P. (2021). Insight into metastatic oral cancer tissue from novel analyses using FTIR spectroscopy and aperture IR-SNOM. ANALYST, 146(15), 4895-4904. doi:10.1039/d1an00922b
2020
A de-waxing methodology for scanning probe microscopy
Al jedani, S., Smith, C., Gunning, P., Ellis, B., Gardner, P., Barrett, S., . . . Weightman, P. (2020). A de-waxing methodology for scanning probe microscopy. Analytical Methods, 12(26), 3397-3403. doi:10.1039/D0AY00965B
iRhom2 in the pathogenesis of oral squamous cell carcinoma
Agwae, M. E., Shaw, R. J., Triantafyllou, A., Greaney, F. S. T., Ben Salah, K., & Risk, J. M. (2020). iRhom2 in the pathogenesis of oral squamous cell carcinoma. MOLECULAR BIOLOGY REPORTS, 47(5), 3987-3992. doi:10.1007/s11033-020-05381-y
Essential characterisation of Human papillomavirus positive Head and Neck cancer cell lines
Greaney-Davies, F. S. T., Risk, J., Robinson, M., Liloglou, T., Shaw, R., & Schache, A. (2020). Essential characterisation of Human papillomavirus positive Head and Neck cancer cell lines. Oral Oncology, 103. doi:10.1016/j.oraloncology.2020.104613
Overexpression of <i>HURP</i> mRNA in head and neck carcinoma and association with <i>in vitro</i> response to vinorelbine
Al-Khafaji, A. S. K., Pantazi, P., Acha-Sagredo, A., Schache, A., Risk, J. M., Shaw, R. J., & Liloglou, T. (2020). Overexpression of <i>HURP</i> mRNA in head and neck carcinoma and association with <i>in vitro</i> response to vinorelbine. ONCOLOGY LETTERS, 19(3), 2502-2507. doi:10.3892/ol.2020.11339
2019
Exploring the potential of BH3 mimetic therapy in squamous cell carcinoma of the head and neck
Carter, R. J., Milani, M., Butterworth, M., Alotibi, A., Harper, N., Yedida, G., . . . Varadarajan, S. (2019). Exploring the potential of BH3 mimetic therapy in squamous cell carcinoma of the head and neck. Cell Death and Disease, 10(12). doi:10.1038/s41419-019-2150-8
Hypoxia and HPV Status in Oropharyngeal Squamous Cell Carcinoma
Ben Salah, K., Triantafyllou, A., Schache, A., Shaw, R. J., & Risk, J. M. (2019). Hypoxia and HPV Status in Oropharyngeal Squamous Cell Carcinoma. In JOURNAL OF PATHOLOGY Vol. 249 (pp. S36). Retrieved from https://www.webofscience.com/
Type 2 Immunity Linked to iRhom2 and Tylosis with Oesophageal Cancer
Murtough, S., Webb, C. M., Chikh, A., Picard, H. L. D., Pink, R., Wang, J., . . . Kelsell, D. P. (2019). Type 2 Immunity Linked to iRhom2 and Tylosis with Oesophageal Cancer. In JOURNAL OF INVESTIGATIVE DERMATOLOGY Vol. 139 (pp. S287). doi:10.1016/j.jid.2019.07.425
Analysis of head and neck carcinoma progression reveals novel and relevant stage-specific changes associated with immortalisation and malignancy
Veeramachaneni, R., Walker, T., Revil, T., De Weck, A., Badescu, D., O'Sullivan, J., . . . Thakker, N. (2019). Analysis of head and neck carcinoma progression reveals novel and relevant stage-specific changes associated with immortalisation and malignancy. SCIENTIFIC REPORTS, 9. doi:10.1038/s41598-019-48229-7
iRhom2-mediated immune dysregulation: Impact on the skin and oesophagus
Webb, C., Murtough, S., Chikh, A., Picard, H. L. D., Wang, J., Pink, R., . . . Kelsell, D. P. (2019). iRhom2-mediated immune dysregulation: Impact on the skin and oesophagus. In JOURNAL OF INVESTIGATIVE DERMATOLOGY Vol. 139 (pp. S78). Retrieved from https://www.webofscience.com/
LaNt α31 influences cell adhesion and migration through modulation of laminin organisation and hemidesmosome maturation
Troughton, L. D., Iorio, V., Barrera, V., Shaw, L., Zech, T., Risk, J., & Hamill, K. J. (2019). LaNt α31 influences cell adhesion and migration through modulation of laminin organisation and hemidesmosome maturation. In INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY Vol. 100 (pp. A38-A39). Retrieved from https://www.webofscience.com/
2018
Molecular pathogenesis of proliferative verrucous leukoplakia: a systematic review
Okoturo, E. M., Risk, J. M., Schache, A. G., Shaw, R. J., & Boyd, M. T. (2018). Molecular pathogenesis of proliferative verrucous leukoplakia: a systematic review. BRITISH JOURNAL OF ORAL & MAXILLOFACIAL SURGERY, 56(09), 780-785. doi:10.1016/j.bjoms.2018.08.010
PO-027 Potential use of BH3 mimetics in the treatment of head and neck cancer
Carter, R. J., Butterworth, M., Risk, J. M., Jorgensen, A. L., Sacco, J. J., Schache, A. G., . . . Varadarajan, S. (2018). PO-027 Potential use of BH3 mimetics in the treatment of head and neck cancer. In ESMO Open Vol. 3 (pp. A238). Elsevier BV. doi:10.1136/esmoopen-2018-eacr25.562
A splicing switch provides dual layer control of laminin alpha3: Implications for squamous cell carcinoma
Troughton, L. D., Barrera, V., Brown, L., Zech, T., Willoughby, C. E., Risk, J. M., & Hamill, K. J. (2018). A splicing switch provides dual layer control of laminin alpha3: Implications for squamous cell carcinoma. In JOURNAL OF INVESTIGATIVE DERMATOLOGY Vol. 138 (pp. S147). doi:10.1016/j.jid.2018.03.876
Infrared imaging of oral squamous cell carcinoma can distinguish carcinoma from other cell types
Risk, J., Ellis, B., Chadwick, J., Ingham, J., Shaw, R., & Weightman, P. (2018). Infrared imaging of oral squamous cell carcinoma can distinguish carcinoma from other cell types. In European Journal of Surgical Oncology Vol. 44 (pp. S51). Elsevier BV. doi:10.1016/j.ejso.2018.01.024
Metabolic organization in HPV+ oropharyngeal squamous cell carcinoma
Ben Salah, K., Triantafyllou, A., Schache, A., Shaw, R., & Risk, J. M. (2018). Metabolic organization in HPV+ oropharyngeal squamous cell carcinoma. In European Journal of Surgical Oncology Vol. 44 (pp. S8). Elsevier BV. doi:10.1016/j.ejso.2018.01.487
2017
Management of Proliferative Verrucous Leukoplakia: justification for a conservative approach
Okoturo, E., Risk, J., Boyd, M., Ho, M., Triantafyllou, A., Rajlawat, B., . . . Shaw, R. (2017). Management of Proliferative Verrucous Leukoplakia: justification for a conservative approach. In British Journal of Oral and Maxillofacial Surgery Vol. 55 (pp. e69). Elsevier BV. doi:10.1016/j.bjoms.2017.08.314
Metabolic organization in HPV+ oropharyngeal squamous cell carcinoma
Ben Salah, K., Triantafyllou, A., Schache, A., Shaw, R., & Risk, J. M. (2017). Metabolic organization in HPV+ oropharyngeal squamous cell carcinoma. In European Journal of Surgical Oncology Vol. 43 (pp. 2208). Elsevier BV. doi:10.1016/j.ejso.2017.10.090
Using the patients concerns inventory for distress screening in post-treatment head and neck cancer survivors
Ghazali, N., Roe, B., Lowe, D., Tandon, S., Jones, T. M., Shaw, R. J., . . . Rogers, S. N. (2017). Using the patients concerns inventory for distress screening in post-treatment head and neck cancer survivors. Journal of Cranio-Maxillofacial Surgery, 45(10), 1743-1748. doi:10.1016/j.jcms.2017.07.009
Management of proliferative verrucous leukoplakia: Justification for a conservative approach.
Borgna, S. C., Clarke, P. T., Schache, A. G., Lowe, D., Ho, M. W., McCarthy, C. E., . . . Shaw, R. J. (2017). Management of proliferative verrucous leukoplakia: Justification for a conservative approach.. Head & neck, 39(10), 1997-2003. doi:10.1002/hed.24845
Modulating the DNA Damage Response to Improve Treatment Response in Cervical Cancer
Cossar, L. H., Schache, A. G., Risk, J. M., Sacco, J. J., Jones, N. J., & Lord, R. (2017). Modulating the DNA Damage Response to Improve Treatment Response in Cervical Cancer. Clinical Oncology, 29(9), 626-634. doi:10.1016/j.clon.2017.03.002
AURKA mRNA expression is an independent predictor of poor prognosis in patients with non-small cell lung cancer
Al-Khafaji, A. S. K., Marcus, M. W., Davies, M. P. A., Risk, J. M., Shaw, R. J., Field, J. K., & Liloglou, T. (2017). AURKA mRNA expression is an independent predictor of poor prognosis in patients with non-small cell lung cancer. Oncology letters, 13(6), 4463-4468. doi:10.3892/ol.2017.6012
Screening for distress using the distress thermometer and the University of Washington Quality of Life in post-treatment head and neck cancer survivors
Ghazali, N., Roe, B., Lowe, D., Tandon, S., Jones, T., Brown, J., . . . Rogers, S. (2017). Screening for distress using the distress thermometer and the University of Washington Quality of Life in post-treatment head and neck cancer survivors. European Archives of Oto-Rhino-Laryngology, 274(5), 2253-2260. doi:10.1007/s00405-017-4474-2
Aurora B expression modulates paclitaxel response in non-small cell lung cancer.
Al-Khafaji, A. S., Davies, M. P., Risk, J. M., Marcus, M. W., Koffa, M., Gosney, J. R., . . . Liloglou, T. (2017). Aurora B expression modulates paclitaxel response in non-small cell lung cancer.. British journal of cancer, 116(05), 592-599. doi:10.1038/bjc.2016.453
Prognostic Factors in Oral, Oropharyngeal, and Salivary Gland Cancer
Shaw, R. J., Brown, J., Ettl, T., & Risk, J. M. (2017). Prognostic Factors in Oral, Oropharyngeal, and Salivary Gland Cancer. In Maxillofacial Surgery (pp. 257-274). Elsevier. doi:10.1016/b978-0-7020-6056-4.00015-0
2016
Invasion of low passage oral carcinoma cells in organotypic models is influenced by the source of both the cancer and cancer-associated fibroblast cells
Dhanda, J., Stanbury, J., Triantafyllou, A., Acha-Sagredo, A., Wilson, J., Woolgar, J., . . . Risk, J. (2016). Invasion of low passage oral carcinoma cells in organotypic models is influenced by the source of both the cancer and cancer-associated fibroblast cells. In British Journal of Oral and Maxillofacial Surgery Vol. 54 (pp. e167). Elsevier BV. doi:10.1016/j.bjoms.2016.11.283
Intraoperative Sentinel Lymph Node Evaluation: Implications of Cytokeratin 19 Expression for the Adoption of OSNA in Oral Squamous Cell Carcinoma
Shaw, R., Christensen, A., Java, K., El Maddani, R., Liloglou, T., Asterios, T., . . . Robinson, M. (2016). Intraoperative Sentinel Lymph Node Evaluation: Implications of Cytokeratin 19 Expression for the Adoption of OSNA in Oral Squamous Cell Carcinoma. ANNALS OF SURGICAL ONCOLOGY, 23(12), 4042-4048. doi:10.1245/s10434-016-5337-6
NOTCH1 mutations and extracapsular spread in oral squamous cell carcinoma lymph node metastasis
Bhattacharya, P., Risk, J., Dhanda, J., Shaw, R., Lloyd, B., & Sibson, D. R. (2016). NOTCH1 mutations and extracapsular spread in oral squamous cell carcinoma lymph node metastasis. In European Journal of Surgical Oncology (EJSO) Vol. 42 (pp. S230). Elsevier BV. doi:10.1016/j.ejso.2016.07.061
Features and prognostic utility of biopsy in oral squamous cell carcinoma
Dhanda, J., Uppal, N., Chowlia, H., Opie, N., Al-Qamachi, L. H., Shelate, D., . . . Mehanna, H. (2016). Features and prognostic utility of biopsy in oral squamous cell carcinoma. Head and Neck, 38(S1), E1857-E1862. doi:10.1002/hed.24335
2015
Determining the origin of primary cell culture derived fibroblasts that influence the invasive front in organotypic models using allelic imbalance with microsatellite markers
Dhanda, J., Stanbury, J., Triantafyllou, A., Acha-Sagredo, A., Wilson, J., Woolgar, J., . . . Risk, J. (2015). Determining the origin of primary cell culture derived fibroblasts that influence the invasive front in organotypic models using allelic imbalance with microsatellite markers. In British Journal of Oral and Maxillofacial Surgery Vol. 53 (pp. e99). Elsevier BV. doi:10.1016/j.bjoms.2015.08.177
Evaluation of the DNA damage repair pathway through oral epithelial dysplasia scrapes: its role in the determination of malignant transformation
Ho, M., Gupta, J., Risk, J., Triantafyllou, A., Shaw, R., & Wilson, J. (2015). Evaluation of the DNA damage repair pathway through oral epithelial dysplasia scrapes: its role in the determination of malignant transformation. In British Journal of Oral and Maxillofacial Surgery Vol. 53 (pp. e111). Elsevier BV. doi:10.1016/j.bjoms.2015.08.208
SERPINE1 and SMA expression at the invasive front predict extracapsular spread and survival in oral squamous cell carcinoma
Dhanda, J., Triantafyllou, A., Lilogou, T., Kalarai, H., Hanlon, R., Lloyd, B., . . . Risk, J. (2015). SERPINE1 and SMA expression at the invasive front predict extracapsular spread and survival in oral squamous cell carcinoma. In British Journal of Oral and Maxillofacial Surgery Vol. 53 (pp. e113). Elsevier BV. doi:10.1016/j.bjoms.2015.08.213
Tylosis with oesophageal cancer: Diagnosis, management and molecular mechanisms
Ellis, A., Risk, J. M., Maruthappu, T., & Kelsell, D. P. (2015). Tylosis with oesophageal cancer: Diagnosis, management and molecular mechanisms. ORPHANET JOURNAL OF RARE DISEASES, 10. doi:10.1186/s13023-015-0346-2
Evaluation of the co-existence of the red fluorescent plaque bacteria <i>P</i>. <i>gingivalis</i> with <i>S</i>. <i>gordonii</i> and <i>S</i>. <i>mutans</i> in white spot lesion formation during orthodontic treatment
Sadeq, A., Risk, J. M., Pender, N., Higham, S. M., & Valappil, S. P. (2015). Evaluation of the co-existence of the red fluorescent plaque bacteria <i>P</i>. <i>gingivalis</i> with <i>S</i>. <i>gordonii</i> and <i>S</i>. <i>mutans</i> in white spot lesion formation during orthodontic treatment. PHOTODIAGNOSIS AND PHOTODYNAMIC THERAPY, 12(2), 232-237. doi:10.1016/j.pdpdt.2015.03.001
Genetic epidemiology of oesophageal cancer
Ellis, A., & Risk, J. (2015). Genetic epidemiology of oesophageal cancer. In C. Probert (Ed.), Recent Advances in Gastroenterology (Vol. 13, pp. 1-12). J.P. Medical Ltd.
2014
SERPINE1 and SMA expression at the invasive front predict extracapsular spread and survival in oral squamous cell carcinoma
Dhanda, J., Triantafyllou, A., Liloglou, T., Kalirai, H., Lloyd, B., Hanlon, R., . . . Risk, J. (2014). SERPINE1 and SMA expression at the invasive front predict extracapsular spread and survival in oral squamous cell carcinoma. British Journal of Cancer, 111(11), 2114-2121. doi:10.1038/bjc.2014.500
Squamous cell carcinoma of the head and neck outside the oropharynx is rarely human papillomavirus related.
Upile, N., Shaw, R., Jones, T., Goodyear, P., Liloglou, L., Risk, J., . . . Schache, A. (2014). Squamous cell carcinoma of the head and neck outside the oropharynx is rarely human papillomavirus related.. The Laryngoscope, 124(12), 2739-2744. doi:10.1002/lary.24828
Oral epithelial dysplasia: the role of ATR-Fanconi anaemia pathway in malignant transformation
Ho, M., Triantafyllou, A., Risk, J. M., Shaw, R. J., & Wilson, J. B. (2014). Oral epithelial dysplasia: the role of ATR-Fanconi anaemia pathway in malignant transformation. In British Journal of Oral and Maxillofacial Surgery Vol. 52 (pp. e45). Elsevier BV. doi:10.1016/j.bjoms.2014.07.012
Oral epithelial dysplasia: the role of ATR-Fanconi anaemia pathway in malignant transformation
Ho, M., Triantafyllou, A., Risk, J. M., Shaw, R. J., & Wilson, J. B. (2014). Oral epithelial dysplasia: the role of ATR-Fanconi anaemia pathway in malignant transformation. In British Journal of Oral and Maxillofacial Surgery Vol. 52 (pp. e120). Elsevier BV. doi:10.1016/j.bjoms.2014.07.234
2013
Outcomes of oral squamous cell carcinoma arising from oral epithelial dysplasia: rationale for monitoring premalignant oral lesions in a multidisciplinary clinic
Ho, M. W., Field, E. A., Field, J. K., Risk, J. M., Rajlawat, B. P., Rogers, S. N., . . . Shaw, R. J. (2013). Outcomes of oral squamous cell carcinoma arising from oral epithelial dysplasia: rationale for monitoring premalignant oral lesions in a multidisciplinary clinic. BRITISH JOURNAL OF ORAL & MAXILLOFACIAL SURGERY, 51(7), 594-599. doi:10.1016/j.bjoms.2013.03.014
Molecular Staging of Surgical Margins in Oral Squamous Cell Carcinoma Using Promoter Methylation of p16<SUP>INK4A</SUP>, Cytoglobin, E-cadherin, and <i>TMEFF2</i>
Shaw, R. J., Hobkirk, A. J., Nikolaidis, G., Woolgar, J. A., Triantafyllou, A., Brown, J. S., . . . Risk, J. M. (2013). Molecular Staging of Surgical Margins in Oral Squamous Cell Carcinoma Using Promoter Methylation of p16<SUP>INK4A</SUP>, Cytoglobin, E-cadherin, and <i>TMEFF2</i>. ANNALS OF SURGICAL ONCOLOGY, 20(8), 2796-2802. doi:10.1245/s10434-012-2713-8
Saliva collection methods for DNA biomarker analysis in oral cancer patients
Matthews, A. M., Kaur, H., Dodd, M., D'Souza, J., Liloglou, T., Shaw, R. J., & Risk, J. M. (2013). Saliva collection methods for DNA biomarker analysis in oral cancer patients. BRITISH JOURNAL OF ORAL & MAXILLOFACIAL SURGERY, 51(5), 394-398. doi:10.1016/j.bjoms.2012.09.017
Validation of a novel diagnostic standard in HPV-positive oropharyngeal squamous cell carcinoma
Schache, A. G., Liloglou, T., Risk, J. M., Jones, T. M., Ma, X. -J., Wang, H., . . . Robinson, M. (2013). Validation of a novel diagnostic standard in HPV-positive oropharyngeal squamous cell carcinoma. BRITISH JOURNAL OF CANCER, 108(6), 1332-1339. doi:10.1038/bjc.2013.63
The epigenetic landscape of oral squamous cell carcinoma
Jithesh, P. V., Risk, J. M., Schache, A. G., Dhanda, J., Lane, B., Liloglou, T., & Shaw, R. J. (2013). The epigenetic landscape of oral squamous cell carcinoma. BRITISH JOURNAL OF CANCER, 108(2), 370-379. doi:10.1038/bjc.2012.568
2012
Genomic determinants of normal tissue toxicity after radiotherapy for head and neck malignancy: A systematic review
Ghazali, N., Shaw, R. J., Rogers, S. N., & Risk, J. M. (2012). Genomic determinants of normal tissue toxicity after radiotherapy for head and neck malignancy: A systematic review. ORAL ONCOLOGY, 48(11), 1090-1100. doi:10.1016/j.oraloncology.2012.08.002
The clinical determinants of malignant transformation in oral epithelial dysplasia
Ho, M. W., Risk, J. M., Woolgar, J. A., Field, E. A., Field, J. K., Steele, J. C., . . . Shaw, R. J. (2012). The clinical determinants of malignant transformation in oral epithelial dysplasia. ORAL ONCOLOGY, 48(10), 969-976. doi:10.1016/j.oraloncology.2012.04.002
A compelling argument for routine use of RNAScope in oropharynx SCC HPV testing
Schache, A., Risk, J. M., Liloglou, T., Jones, T., Ma, X. -J., Wang, H., . . . Robinson, M. (2012). A compelling argument for routine use of RNAScope in oropharynx SCC HPV testing. In British Journal of Oral and Maxillofacial Surgery Vol. 50 (pp. S34). Elsevier BV. doi:10.1016/j.bjoms.2012.04.234
Clinical determinants of malignant transformation in oral dysplasia
Ho, M. W. S., Risk, J. K., Liloglou, L., Rogers, S. N., Field, E. A., Rajalwat, B., . . . Shaw, R. J. (2012). Clinical determinants of malignant transformation in oral dysplasia. In British Journal of Oral and Maxillofacial Surgery Vol. 50 (pp. S18). Elsevier BV. doi:10.1016/j.bjoms.2012.04.193
Comparison of histological features seen in primary OSCC sites with three dimensional cell culture models of invasion using primary cell lines derived from the same patients
Dhanda, J., Risk, J., Stanbury, J., Woolgar, J., Triantafyllou, A., Brown, J., . . . Sibson, R. (2012). Comparison of histological features seen in primary OSCC sites with three dimensional cell culture models of invasion using primary cell lines derived from the same patients. In British Journal of Oral and Maxillofacial Surgery Vol. 50 (pp. S32). Elsevier BV. doi:10.1016/j.bjoms.2012.04.228
Developing and characterising the Liverpool head and neck cancer cell lines: a unique opportunity to explore epithelial and mesenchymal interactions
Dhanda, J., Risk, J., Stanbury, J., Bekiroglu, F., Brown, J., Rogers, S., . . . Sibson, R. (2012). Developing and characterising the Liverpool head and neck cancer cell lines: a unique opportunity to explore epithelial and mesenchymal interactions. In British Journal of Oral and Maxillofacial Surgery Vol. 50 (pp. S30). Elsevier BV. doi:10.1016/j.bjoms.2012.04.224
Invasive properties in OSCC are both tumour and stroma dependent: compelling evidence from organotypic models
Dhanda, J., Risk, J., Stanbury, J., Woolgar, J., Triantafyllou, A., Brown, J., . . . Sibson, R. (2012). Invasive properties in OSCC are both tumour and stroma dependent: compelling evidence from organotypic models. In British Journal of Oral and Maxillofacial Surgery Vol. 50 (pp. S31). Elsevier BV. doi:10.1016/j.bjoms.2012.04.226
Post-treatment proximal oesophageal strictures in head and neck carcinoma
Ghazali, N., Noor Ullah, O., Shaw, R., Risk, J., Lowe, D., Jones, T., . . . Kapoor, N. (2012). Post-treatment proximal oesophageal strictures in head and neck carcinoma. In British Journal of Oral and Maxillofacial Surgery Vol. 50 (pp. S35). Elsevier BV. doi:10.1016/j.bjoms.2012.04.237
Validation for a novel diagnostic standard in HPV-positive oropharyngeal squamous cell carcinoma.
Ma, X. -J., Schache, A., Liloglou, T., Risk, J., Jones, T., Wang, H., . . . Robinson, M. (2012). Validation for a novel diagnostic standard in HPV-positive oropharyngeal squamous cell carcinoma.. Journal of Clinical Oncology, 30(15_suppl), 5543. doi:10.1200/jco.2012.30.15_suppl.5543
OSTEORADIONECROSIS IN HEAD-AND-NECK CANCER HAS A DISTINCT GENOTYPE-DEPENDENT CAUSE
Lyons, A. J., West, C. M., Risk, J. M., Slevin, N. J., Chan, C., Crichton, S., . . . Shaw, R. J. (2012). OSTEORADIONECROSIS IN HEAD-AND-NECK CANCER HAS A DISTINCT GENOTYPE-DEPENDENT CAUSE. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 82(4), 1479-1484. doi:10.1016/j.ijrobp.2011.05.016
Protection from Intracellular Oxidative Stress by Cytoglobin in Normal and Cancerous Oesophageal Cells
McRonald, F. E., Risk, J. M., & Hodges, N. J. (2012). Protection from Intracellular Oxidative Stress by Cytoglobin in Normal and Cancerous Oesophageal Cells. PLOS ONE, 7(2). doi:10.1371/journal.pone.0030587
<i>RHBDF2</i> Mutations Are Associated with Tylosis, a Familial Esophageal Cancer Syndrome
Blaydon, D. C., Etheridge, S. L., Risk, J. M., Hennies, H. -C., Gay, L. J., Carroll, R., . . . Kelsell, D. P. (2012). <i>RHBDF2</i> Mutations Are Associated with Tylosis, a Familial Esophageal Cancer Syndrome. AMERICAN JOURNAL OF HUMAN GENETICS, 90(2), 340-346. doi:10.1016/j.ajhg.2011.12.008
2011
Evaluation of Human Papilloma Virus Diagnostic Testing in Oropharyngeal Squamous Cell Carcinoma: Sensitivity, Specificity, and Prognostic Discrimination
Schache, A. G., Liloglou, T., Risk, J. M., Filia, A., Jones, T. M., Sheard, J., . . . Shaw, R. J. (2011). Evaluation of Human Papilloma Virus Diagnostic Testing in Oropharyngeal Squamous Cell Carcinoma: Sensitivity, Specificity, and Prognostic Discrimination. CLINICAL CANCER RESEARCH, 17(19), 6262-6271. doi:10.1158/1078-0432.CCR-11-0388
RE: P16 INK41 promoter hypermethylation is associated with invasiveness and prognosis of oral squamous cell carcinoma in an age dependent manner. Su et al. Oral Oncology 46 (2010) 734-739
Shaw, R., Risk, J. M., & Liloglou, T. (2011). RE: P16 INK41 promoter hypermethylation is associated with invasiveness and prognosis of oral squamous cell carcinoma in an age dependent manner. Su et al. Oral Oncology 46 (2010) 734-739. ORAL ONCOLOGY, 47(8), 776. doi:10.1016/j.oraloncology.2010.10.014
A molecular signature to aid in the clinical diagnosis of ECS in OSCC
Dhanda, J., Shaw, R., Hanlon, B., Lloyd, B., Risk, J., Woolgar, J. A., & Sibson, R. (2011). A molecular signature to aid in the clinical diagnosis of ECS in OSCC. In British Journal of Oral and Maxillofacial Surgery Vol. 49 (pp. S16). Elsevier BV. doi:10.1016/j.bjoms.2011.04.042
Defining a prognostic biomarker in HPV-positive oropharyngeal SCC
Schache, A., Robinson, M., Risk, J. M., Liloglou, T., & Shaw, R. (2011). Defining a prognostic biomarker in HPV-positive oropharyngeal SCC. In British Journal of Oral and Maxillofacial Surgery Vol. 49 (pp. S11-S12). Elsevier BV. doi:10.1016/j.bjoms.2011.04.030
Does human papillomavirus 16 (HPV16) have a role in malignant or premalignant lesions of the oral cavity?
Schache, A., Matthews, A., Newey, C., Risk, J. M., Liloglou, T., & Shaw, R. J. (2011). Does human papillomavirus 16 (HPV16) have a role in malignant or premalignant lesions of the oral cavity?. In British Journal of Oral and Maxillofacial Surgery Vol. 49 (pp. S12). Elsevier BV. doi:10.1016/j.bjoms.2011.04.032
Abstract 5246: Genomic determinants of aggressive phenotype in oral SCC
Sibson, D. R., Lloyd, B., Woolgar, J., Risk, J., Shaw, R., & Dhanda, J. (2011). Abstract 5246: Genomic determinants of aggressive phenotype in oral SCC. In Cancer Research Vol. 71 (pp. 5246). American Association for Cancer Research (AACR). doi:10.1158/1538-7445.am2011-5246
2010
Quantitative promoter methylation differentiates carcinoma ex pleomorphic adenoma from pleomorphic salivary adenoma
Schache, A. G., Hall, G., Woolgar, J. A., Nikolaidis, G., Triantafyllou, A., Lowe, D., . . . Liloglou, T. (2010). Quantitative promoter methylation differentiates carcinoma ex pleomorphic adenoma from pleomorphic salivary adenoma. BRITISH JOURNAL OF CANCER, 103(12), 1846-1851. doi:10.1038/sj.bjc.6605953
17 Novel epigenetic biomarkers of minimal residual disease in oral cancer
Hobkirk, A. J., Nikolaidis, G., Liloglou, T., Risk, J. M., & Shaw, R. J. (2010). 17 Novel epigenetic biomarkers of minimal residual disease in oral cancer. In British Journal of Oral and Maxillofacial Surgery Vol. 48 (pp. S5). Elsevier BV. doi:10.1016/s0266-4356(10)60018-6
9 What is normal? Validation of cancer biomarkers using saliva from a control group
Matthews, A. M., Kaur, H., Liloglou, L., Shaw, R., & Risk, J. (2010). 9 What is normal? Validation of cancer biomarkers using saliva from a control group. In British Journal of Oral and Maxillofacial Surgery Vol. 48 (pp. S3). Elsevier BV. doi:10.1016/s0266-4356(10)60010-1
2009
Detection of oral squamous cell carcinoma using epigenetic biomarkers in saliva derived DNA
Matthews, A. M., Dodd, M., Reid, M., Shaw, R., & Risk, J. (2009). Detection of oral squamous cell carcinoma using epigenetic biomarkers in saliva derived DNA. In British Journal of Oral and Maxillofacial Surgery Vol. 47 (pp. e4-e5). Elsevier BV. doi:10.1016/j.bjoms.2009.06.139
Cytoglobin is upregulated by tumour hypoxia and silenced by promoter hypermethylation in head and neck cancer
Shaw, R. J., Omar, M. M., Rokadiya, S., Kogera, F. A., Lowe, D., Hall, G. L., . . . Risk, J. M. (2009). Cytoglobin is upregulated by tumour hypoxia and silenced by promoter hypermethylation in head and neck cancer. BRITISH JOURNAL OF CANCER, 101(1), 139-144. doi:10.1038/sj.bjc.6605121
2008
p16 promoter methylation predicts malignant transformation in oral epithelial dysplasia
Shaw, R. J., Hall, G. L., Sutton, D. N., & Risk, J. M. (2008). p16 promoter methylation predicts malignant transformation in oral epithelial dysplasia. In British Journal of Oral and Maxillofacial Surgery Vol. 46 (pp. e47-e48). Elsevier BV. doi:10.1016/j.bjoms.2008.07.046
<i>p16</i> promoter methylation is a potential predictor of malignant transformation in oral epithelial dysplasia
Hall, G. L., Shaw, R. J., Field, E. A., Rogers, S. N., Sutton, D. N., Woolgar, J. A., . . . Risk, J. M. (2008). <i>p16</i> promoter methylation is a potential predictor of malignant transformation in oral epithelial dysplasia. CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION, 17(8), 2174-2179. doi:10.1158/1055-9965.EPI-07-2867
The role of pyrosequencing in head and neck cancer epigenetics - Correlation of quantitative methylation data with gene expression
Shaw, R. J., Hall, G. L., Lowe, D., Liloglou, T., Field, J. K., Sloan, P., & Risk, J. M. (2008). The role of pyrosequencing in head and neck cancer epigenetics - Correlation of quantitative methylation data with gene expression. ARCHIVES OF OTOLARYNGOLOGY-HEAD & NECK SURGERY, 134(3), 251-256. doi:10.1001/archoto.2007.50
Tissue banking in head and neck cancer
Hall, G. L., Kademani, D., Risk, J. M., & Shaw, R. J. (2008). Tissue banking in head and neck cancer. ORAL ONCOLOGY, 44(2), 109-115. doi:10.1016/j.oraloncology.2007.08.002
2007
Quantitative methylation analysis of resection margins and lymph nodes in oral squamous cell carcinoma
Shaw, R. J., Hall, G. L., Woolgar, J. A., Lowe, D., Rogers, S. N., Field, J. K., . . . Risk, J. M. (2007). Quantitative methylation analysis of resection margins and lymph nodes in oral squamous cell carcinoma. BRITISH JOURNAL OF ORAL & MAXILLOFACIAL SURGERY, 45(8), 617-622. doi:10.1016/j.bjoms.2007.04.015
CpG island methylation phenotype (CIMP) in oral cancer: Associated with a marked inflammatory response and less aggressive tumour biology
Shaw, R. J., Hall, G. L., Lowe, D., Bowers, N. L., Liloglou, T., Field, J. K., . . . Risk, J. M. (2007). CpG island methylation phenotype (CIMP) in oral cancer: Associated with a marked inflammatory response and less aggressive tumour biology. ORAL ONCOLOGY, 43(9), 878-886. doi:10.1016/j.oraloncology.2006.10.006
“CIMP” in head and neck cancer
Shaw, R., Hall, G. L., Lowe, D., Bowers, N. L., Liloglou, T., Field, J. K., . . . Risk, J. M. (2007). “CIMP” in head and neck cancer. In British Journal of Oral and Maxillofacial Surgery Vol. 45 (pp. e42-e43). Elsevier BV. doi:10.1016/j.bjoms.2007.07.041
Characterization of a bifunctional catalase-peroxidase of <i>Burkholderia cenocepacia</i>
Charalabous, P., Risk, J. M., Jenkins, R., Birss, A. J., Hart, C. A., & Smalley, J. W. (2007). Characterization of a bifunctional catalase-peroxidase of <i>Burkholderia cenocepacia</i>. FEMS IMMUNOLOGY AND MEDICAL MICROBIOLOGY, 50(1), 37-44. doi:10.1111/j.1574-695X.2007.00224.x
2006
Evaluation of the <i>4q32-34</i> locus in European familial pancreatic
Earl, J., Yan, L., Vitone, L. J., Risk, J., Kemp, S. J., McFaul, C., . . . Bartsch, D. K. (2006). Evaluation of the <i>4q32-34</i> locus in European familial pancreatic. CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION, 15(10), 1948-1955. doi:10.1158/1055-9965.EPI-06-0376
Re:: !Powers JM. p53-mediated apoptosis, neuroglobin overexpression, and globin deposits in a patient with hereditary ferritinopathy.: J Neuropathol Exp Neurol 2006;: 65:716-27
McRonald, F. E., Shaw, R. J., Omar, M., & Risk, J. M. (2006). Re:: !Powers JM. p53-mediated apoptosis, neuroglobin overexpression, and globin deposits in a patient with hereditary ferritinopathy.: J Neuropathol Exp Neurol 2006;: 65:716-27. JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY, 65(9), 931. doi:10.1097/01.jnen.0000240240.47291.d3
P096 Cytoglobin: A Candidate Tumor Suppressor Gene Epigenetically Silenced in Head and Neck Cancer
Shaw, R. J., Liloglou, T., Field, J. K., & Risk, J. M. (2006). P096 Cytoglobin: A Candidate Tumor Suppressor Gene Epigenetically Silenced in Head and Neck Cancer. In Archives of Otolaryngology–Head & Neck Surgery Vol. 132 (pp. 884). American Medical Association (AMA). doi:10.1001/archotol.132.8.884-b
P182 Clinical Application of Epigenetic Biomarkers in Head and Neck Cancer
Shaw, R. J., Hall, G., Liloglou, T., Rogers, S., Brown, J., Field, J. K., & Risk, J. M. (2006). P182 Clinical Application of Epigenetic Biomarkers in Head and Neck Cancer. In Archives of Otolaryngology–Head & Neck Surgery Vol. 132 (pp. 900). American Medical Association (AMA). doi:10.1001/archotol.132.8.900-c
Frequent genetic and epigenetic abnormalities contribute to the deregulation of cytoglobin in non-small cell lung cancer
Xinarianos, G., McRonald, F. E., Risk, J. M., Bowers, N. L., Nikolaidis, G., Field, J. K., & Liloglou, T. (2006). Frequent genetic and epigenetic abnormalities contribute to the deregulation of cytoglobin in non-small cell lung cancer. HUMAN MOLECULAR GENETICS, 15(13), 2038-2044. doi:10.1093/hmg/ddl128
Methylation enrichment pyrosequencing: combining the specificity of MSP with validation by pyrosequencing
Shaw, R. J., Akufo-Tetteh, E. K., Risk, J. M., Field, J. K., & Liloglou, T. (2006). Methylation enrichment pyrosequencing: combining the specificity of MSP with validation by pyrosequencing. NUCLEIC ACIDS RESEARCH, 34(11). doi:10.1093/nar/gkl424
Down-regulation of the cytoglobin gene, located on 17q25, in tylosis with oesophageal cancer (TOC):: evidence for <i>trans</i>-allele repression
McRonald, F. E., Liloglou, T., Xinarianos, G., Hill, L., Rowbottom, L., Langan, J. E., . . . Risk, J. M. (2006). Down-regulation of the cytoglobin gene, located on 17q25, in tylosis with oesophageal cancer (TOC):: evidence for <i>trans</i>-allele repression. HUMAN MOLECULAR GENETICS, 15(8), 1271-1277. doi:10.1093/hmg/ddl042
Promoter methylation of P16, RARβ, E-cadherin, cyclin A1 and cytoglobin in oral cancer:: quantitative evaluation using pyrosequencing
Shaw, R. J., Liloglou, T., Rogers, S. N., Brown, J. S., Vaughan, E. D., Lowe, D., . . . Risk, J. M. (2006). Promoter methylation of P16, RARβ, E-cadherin, cyclin A1 and cytoglobin in oral cancer:: quantitative evaluation using pyrosequencing. BRITISH JOURNAL OF CANCER, 94(4), 561-568. doi:10.1038/sj.bjc.6602972
2005
Monitoring of circulating tumour-associated DNA as a prognostic tool for oral squamous cell carcinoma.
Thomas, E., Shaw, R. J., & Risk, J. M. (2005). Monitoring of circulating tumour-associated DNA as a prognostic tool for oral squamous cell carcinoma.. British journal of cancer, 93(8), 960. doi:10.1038/sj.bjc.6602801
Abnormal CYGB expression and hypermethylation in non-small cell lung cancer
Liloglou, T., McRonald, F., Xinarianos, G., Bowers, N., Risk, J., & Field, J. (2005). Abnormal CYGB expression and hypermethylation in non-small cell lung cancer. In LUNG CANCER Vol. 49 (pp. S134). doi:10.1016/S0169-5002(05)80572-0
Analysis of familial tylosis oesophageal cancer genes on 17Q25
Rowbottom, L., McRonald, F. E., Langan, J. E., Ellis, A., Field, J. K., & Risk, J. M. (2005). Analysis of familial tylosis oesophageal cancer genes on 17Q25. In CLINICA CHIMICA ACTA Vol. 355 (pp. S167-S168). Retrieved from https://www.webofscience.com/
2004
Novel microsatellite markers and single nucleotide polymorphisms refine the tylosis with oesophageal cancer (<i>TOC</i>) minimal region on 17q25 to 42.5 kb:: sequencing does not identify the causative gene
Langan, J. E., Cole, C. G., Huckle, E. J., Byrne, S., McRonald, F. E., Rowbottom, L., . . . Risk, J. M. (2004). Novel microsatellite markers and single nucleotide polymorphisms refine the tylosis with oesophageal cancer (<i>TOC</i>) minimal region on 17q25 to 42.5 kb:: sequencing does not identify the causative gene. HUMAN GENETICS, 114(6), 534-540. doi:10.1007/s00439-004-1100-3
An investigation of the tylosis with oesophageal cancer (<i>TOC</i>) locus in Iranian patients with oesophageal squamous cell carcinoma
Shahabi, M., Daloii, M. R. N., Langan, J. E., Rowbottom, L., Jahanzad, E., Khoshbin, E., . . . Risk, J. M. (2004). An investigation of the tylosis with oesophageal cancer (<i>TOC</i>) locus in Iranian patients with oesophageal squamous cell carcinoma. INTERNATIONAL JOURNAL OF ONCOLOGY, 25(2), 389-395. Retrieved from https://www.webofscience.com/
Genetic analysis of the tylosis with oesophageal cancer (<i>TOC</i>) gene region on 17q25
McRonald, F. E., Rowbottom, L., Langan, J. E., Ellis, A., Shaw, J. M., Field, J. K., & Risk, J. M. (2004). Genetic analysis of the tylosis with oesophageal cancer (<i>TOC</i>) gene region on 17q25. In BRITISH JOURNAL OF CANCER Vol. 91 (pp. S12). Retrieved from https://www.webofscience.com/
2003
Physical and transcript map of the minimally deleted region III on 17p implicated in the early development of Barrett's oesophageal adenocarcinoma
Dunn, J. R., Risk, J. M., Langan, J. E., Marlee, D., Ellis, A., Campbell, F., . . . Field, J. K. (2003). Physical and transcript map of the minimally deleted region III on 17p implicated in the early development of Barrett's oesophageal adenocarcinoma. ONCOGENE, 22(26), 4134-4142. doi:10.1038/sj.onc.1206466
Allelic imbalance at the DNA mismatch repair loci, <i>hMSH2</i>, <i>hMLH1</i>, <i>hPMS1</i>, <i>hPMS2</i> and <i>hMSH3</i>, in squamous cell carcinoma of the head and neck
Nunn, J., Nagini, S., Risk, J. M., Prime, W., Maloney, P., Liloglou, T., . . . Field, J. K. (2003). Allelic imbalance at the DNA mismatch repair loci, <i>hMSH2</i>, <i>hMLH1</i>, <i>hPMS1</i>, <i>hPMS2</i> and <i>hMSH3</i>, in squamous cell carcinoma of the head and neck. ORAL ONCOLOGY, 39(2), 115-129. doi:10.1016/S1368-8375(02)00028-3
2002
Characterization of a 500 kb region on 17q25 and the exclusion of candidate genes as the familial Tylosis Oesophageal Cancer (<i>TOC</i>) locus
Risk, J. M., Evans, K. E., Jones, J., Langan, J. E., Rowbottom, L., McRonald, F. E., . . . Field, J. K. (2002). Characterization of a 500 kb region on 17q25 and the exclusion of candidate genes as the familial Tylosis Oesophageal Cancer (<i>TOC</i>) locus. ONCOGENE, 21(41), 6395-6402. doi:10.1038/sj.onc.1205768
A comparative guide to gene prediction tools for the bioinformatics amateur
Jones, J., Field, J. K., & Risk, J. M. (2002). A comparative guide to gene prediction tools for the bioinformatics amateur. INTERNATIONAL JOURNAL OF ONCOLOGY, 20(4), 697-705. Retrieved from https://www.webofscience.com/
Sequencing of difficult templates containing poly(A/T) tracts: Closure of sequence gaps
Langan, J. E., Rowbottom, L., Liloglou, T., Field, J. K., & Risk, J. M. (2002). Sequencing of difficult templates containing poly(A/T) tracts: Closure of sequence gaps. BIOTECHNIQUES, 33(2), 276-+. doi:10.2144/02332bm04
1999
The tylosis esophageal cancer (<i>TOC</i>) locus:: more than just a familial cancer gene
Risk, J. M., Mills, H. S., Garde, J., Dunn, J. R., Evans, K. E., Hollstein, M., & Field, J. K. (1999). The tylosis esophageal cancer (<i>TOC</i>) locus:: more than just a familial cancer gene. DISEASES OF THE ESOPHAGUS, 12(3), 173-176. doi:10.1046/j.1442-2050.1999.00042.x
Envoplakin, a possible candidate gene for focal NEPPK/esophageal cancer (<i>TOC</i>):: The integration of genetic and physical maps of the <i>TOC</i> region on 17q25
Risk, J. M., Ruhrberg, C., Hennies, H. C., Mills, H. S., Di Colandrea, T., Evans, K. E., . . . Field, J. K. (1999). Envoplakin, a possible candidate gene for focal NEPPK/esophageal cancer (<i>TOC</i>):: The integration of genetic and physical maps of the <i>TOC</i> region on 17q25. GENOMICS, 59(2), 234-242. doi:10.1006/geno.1999.5857
1998
Loss of heterozygosity in sporadic oesophageal tumors in the tylosis oesophageal cancer (TOC) gene region of chromosome 17q
von Brevern, M., Hollstein, M. C., Risk, J. M., Garde, J., Bennett, W. P., Harris, C. C., . . . Field, J. K. (1998). Loss of heterozygosity in sporadic oesophageal tumors in the tylosis oesophageal cancer (TOC) gene region of chromosome 17q. ONCOGENE, 17(16), 2101-2105. doi:10.1038/sj.onc.1202139
1996
Erratum: Allelotype of squamous cell carcinoma of the head and neck: fractional allele loss correlates with survival
Erratum: Allelotype of squamous cell carcinoma of the head and neck: fractional allele loss correlates with survival (1996). British Journal of Cancer, 74(7), 1153. doi:10.1038/bjc.1996.507
Close mapping of the focal non-epidermolytic palmoplantar keratoderma (PPK) locus associated with oesophageal cancer (TOC)
Kelsell, D. P., Risk, J. M., Leigh, I. M., Stevens, H. P., Ellis, A., Hennies, H. C., . . . Field, J. K. (1996). Close mapping of the focal non-epidermolytic palmoplantar keratoderma (PPK) locus associated with oesophageal cancer (TOC). HUMAN MOLECULAR GENETICS, 5(6), 857-860. doi:10.1093/hmg/5.6.857
Polymorphisms in the promoter region of the WAF1/CIP1 gene
Liloglou, T., Risk, J. M., & Field, J. K. (1996). Polymorphisms in the promoter region of the WAF1/CIP1 gene. INTERNATIONAL JOURNAL OF ONCOLOGY, 9(3), 559-562. Retrieved from https://www.webofscience.com/
1995
ALLELOTYPE OF SQUAMOUS-CELL CARCINOMA OF THE HEAD AND NECK - FRACTIONAL ALLELE LOSS CORRELATES WITH SURVIVAL
FIELD, J. K., KIARIS, H., RISK, J. M., TSIRIYOTIS, C., ADAMSON, R., ZOUMPOURLIS, V., . . . JONES, A. S. (1995). ALLELOTYPE OF SQUAMOUS-CELL CARCINOMA OF THE HEAD AND NECK - FRACTIONAL ALLELE LOSS CORRELATES WITH SURVIVAL. BRITISH JOURNAL OF CANCER, 72(5), 1180-1188. doi:10.1038/bjc.1995.483
FREQUENT LOSS OF HETEROZYGOSITY ON CHROMOSOME-17 AT 17Q11.2-Q12 IN BARRETTS ADENOCARCINOMA
SWIFT, A., RISK, J. M., KINGSNORTH, A. N., WRIGHT, T. A., MYSKOW, M., & FIELD, J. K. (1995). FREQUENT LOSS OF HETEROZYGOSITY ON CHROMOSOME-17 AT 17Q11.2-Q12 IN BARRETTS ADENOCARCINOMA. BRITISH JOURNAL OF CANCER, 71(5), 995-998. doi:10.1038/bjc.1995.191
1994
TYLOSIS ESOPHAGEAL CANCER MAPPED
RISK, J. M., FIELD, E. A., FIELD, J. K., WHITTAKER, J., FRYER, A., ELLIS, A., . . . LEIGH, I. M. (1994). TYLOSIS ESOPHAGEAL CANCER MAPPED. NATURE GENETICS, 8(4), 319-321. doi:10.1038/ng1294-319
Tylosis associated with carcinoma of the oesophagus and oral leukoplakia in a large Liverpool family--a review of six generations.
Ellis, A., Field, J. K., Field, E. A., Friedmann, P. S., Fryer, A., Howard, P., . . . Whittaker, J. (1994). Tylosis associated with carcinoma of the oesophagus and oral leukoplakia in a large Liverpool family--a review of six generations.. European journal of cancer. Part B, Oral oncology, 30B(2), 102-112. doi:10.1016/0964-1955(94)90061-2
1991
Evidence for herpes simplex viral latency in the human cornea.
Kaye, S. B., Lynas, C., Patterson, A., Risk, J. M., McCarthy, K., & Hart, C. A. (1991). Evidence for herpes simplex viral latency in the human cornea.. The British journal of ophthalmology, 75(4), 195-200. doi:10.1136/bjo.75.4.195
Polymorphism of the human CD46 gene in normal individuals and in recurrent spontaneous abortion.
Risk, J. M., Flanagan, B. F., & Johnson, P. M. (1991). Polymorphism of the human CD46 gene in normal individuals and in recurrent spontaneous abortion.. Human immunology, 30(3), 162-167. doi:10.1016/0198-8859(91)90030-d
1990
Northern blot analysis of HLA-G expression by BeWo human choriocarcinoma cells.
Risk, J. M., & Johnson, P. M. (1990). Northern blot analysis of HLA-G expression by BeWo human choriocarcinoma cells.. Journal of reproductive immunology, 18(2), 199-203. doi:10.1016/0165-0378(90)90017-z
1989
Analysis of human trophoblast antigen expression
Johnson, P. M., Risk, J. M., Mwenda, M. J., Ramsden, G. H., Nicholson, G., Maher, P. M., & Kenton, P. (1989). Analysis of human trophoblast antigen expression. In Journal of Reproductive Immunology Vol. 15 (pp. 18). Elsevier BV. doi:10.1016/0165-0378(89)90076-4
1988
Immunological and immunogenetic investigation of recurrent spontaneous abortion.
Johnson, P. M., Chia, K. V., Risk, J. M., Barnes, R. M., & Woodrow, J. C. (1988). Immunological and immunogenetic investigation of recurrent spontaneous abortion.. Disease markers, 6(3), 163-171.
MHC class I expression by developmental tumors: teratocarcinoma stem cells are TCA positive.
Stern, P. L., Morris, A., McMain, A., Risk, J., Beresford, N., Kenny, T., . . . Wilson, L. (1988). MHC class I expression by developmental tumors: teratocarcinoma stem cells are TCA positive.. Human immunology, 22(4), 247-261. doi:10.1016/0198-8859(88)90004-3
1987
Oral administration of erythrocyte membrane antigen does not suppress anti-Rh(D) antibody responses in humans.
Barnes, R. M., Duguid, J. K., Roberts, F. M., Risk, J. M., Johnson, P. M., Finn, R., . . . Clarke, C. A. (1987). Oral administration of erythrocyte membrane antigen does not suppress anti-Rh(D) antibody responses in humans.. Clinical and experimental immunology, 67(1), 220-226.
Class I-like MHC molecules expressed by baboon placental syncytiotrophoblast.
Stern, P. L., Beresford, N., Friedman, C. I., Stevens, V. C., Risk, J. M., & Johnson, P. M. (1987). Class I-like MHC molecules expressed by baboon placental syncytiotrophoblast.. Journal of immunology (Baltimore, Md. : 1950), 138(4), 1088-1091.
1986
Fetal and maternal uteroplacental leucocytes in aplastic anaemia. Case report.
Spearing, R., Mackie, M. J., Risk, J. M., Johnson, P. M., & Bulmer, J. N. (1986). Fetal and maternal uteroplacental leucocytes in aplastic anaemia. Case report.. British journal of obstetrics and gynaecology, 93(11), 1163-1165. doi:10.1111/j.1471-0528.1986.tb08639.x
Isolation of placental-type alkaline phosphatase associated with human syncytiotrophoblast membranes using monoclonal antibodies.
Webb, P. D., McLaughlin, P. J., Risk, J. M., & Johnson, P. M. (1986). Isolation of placental-type alkaline phosphatase associated with human syncytiotrophoblast membranes using monoclonal antibodies.. Placenta, 7(5), 405-415. doi:10.1016/s0143-4004(86)80028-5
1985
Antigen expression by human trophoblast and tumour cells: models for gene regulation?
Risk, J. M., & Johnson, P. M. (1985). Antigen expression by human trophoblast and tumour cells: models for gene regulation?. Contributions to gynecology and obstetrics, 14, 74-82.
Immunogenetic studies of recurrent spontaneous abortions in humans.
Johnson, P. M., Barnes, R. M., Risk, J. M., Molloy, C. M., & Woodrow, J. C. (1985). Immunogenetic studies of recurrent spontaneous abortions in humans.. Experimental and clinical immunogenetics, 2(2), 77-83.