Bacterial Pathogenesis and Immunity

Professor Aras Kadioglu in the laboratory with members of his research group

News‌‌

November 2017 | Saudi Ambassador to the UK Honours Outstanding Students

Prince Mohammed bin Nawaf bin Abdulaziz, Saudi Ambassador to the United Kingdom, has honoured 60 outstanding students in various disciplines at The Royal Embassy of Saudi Arabia. Read More...


March 2017 | Phage therapy shown to kill drug-resistant superbug

Scientists from the University of Liverpool’s Institute of Infection and Global Health have shown that phage therapy could offer a safe and effective alternative to antibiotics in the treatment of Cystic Fibrosis lung infections. Read More...


December 2016 | JPI-AMR

AMR in Streptococcus pneumoniae is spread globally by a limited number of clones. PCV vaccination has decreased AMR among vaccine-type strains. AMR now emerges by expansion of non-PCV types. The project focuses on genetic/functional properties of AMR clones with the goal to target their success and transmission in the carrier population.. Read More...


December 2016 | 5 Year Programme Grant Awarded

Lead by Professor Aras Kadioglu, this project aims to improve our understanding of the process of natural colonisation and persistence of Streptococcus pneumoniae in the upper airways. We aim to uncover the interaction of bacteria with host cells in the airways in order to understand how silent infection occurs. Finally, we will determine what factors (bacterial, host or environmental) that lead from upper airway infection to the development of invasive disease. Read More...


November 2016 | Simple changes to antibiotic treatment of MRSA may help beat the bacteria

A study co-lead by Professor Aras Kadioglu have identified how MRSA may be more effectively treated by modern-day antibiotics, if old-fashioned penicillin is also used. Read More...


October 2016 | Action Medical Research Grant Awarded

Around 10,800 people in the UK – including over 4,000 children – have an inherited lung condition called cystic fibrosis (CF).1 Children with CF are susceptible to chest infections which can be difficult to treat, often persisting for the rest of a child’s life and reducing life expectancy. Dr Jo Fothergill, of the University of Liverpool, is investigating what makes these infections so difficult to treat, and how to diagnose them sooner, with the ultimate aim of protecting children from lifelong infections and improving their outlook. Read More...


September 2016 | Pre-clinical development of a new generation of pneumococcal vaccines.

Prof Aras Kadioglu, Dr Marie Yang and Dr Dean Everett were awarded £246,783 from Meningitis Now for the project “The preclinical development and evaluation of a mucosal protein-based adjuvanted vaccine against pneumococcal meningitis and sepsis”. Read More...


July 2016 | Hot Desert storms increase risk of bacterial meningitis in Africa

A study led by Professor Aras Kadioglu found that exposure to airborne dust and high temperatures are significant risk factors for bacterial meningitis. Read more...


May 2015 | Scientists discover bacterial cause behind fatal heart complications

A multidisciplinary research team, led by Professor Aras Kadioglu and Professor Cheng-Hock Toh, has discovered a key cause of life threatening heart complications that frequently follow severe infections with Streptococcus pneumoniae. Read more...


Nov 2014 | New treatment for life-threatening bacterial diseases identified

Research published in Nature Biotechnology shows that liposomes can be used to prevent bacterial toxins from killing human cells. Read more...


Sep 2014 | Researchers uncover hidden infection route of major bacterial pathogen

Research published in Nature Communications reports for the first time that Pseudomonas aeruginosa, which causes severe lung infections in people with cystic fibrosis, colonises the nasopharynx. Read more...


Jul 2014 | Mechanism that prevents lethal bacteria from causing invasive disease is revealed

An important development in understanding how Streptococcus pneumoniae, which causes pneumonia, meningitis and septicaemia, remains harmlessly in the nose and throat has been discovered. Read more...


Sep 2013 | Crafting Science at the Green Man Festival

PhD student Suzy Gore took part in this public engagement event with colleagues from the Institute, and spoke to festival-goers about her work. Read more...


Apr 2013 | Analysing meningitis genes to identify new treatments

New research, supported by Meningitis UK, is using advanced bioinformatics and infection biology tools to identify the bacterial meningitis genes and their products associated with disease so that they can be targeted for new treatments and vaccines. Read more...


May 2011 | New Professors join the University to tackle global infectious diseases

Professor Aras Kadioglu appointed to the Institute of Infection and Global Health as part of a wider £20 million initiative to attract world-class researchers to the University’s Faculty of Health and Life Sciences. Read more...