Early phase trials of “first in childhood disease” are rarely performed in paediatric rheumatology to date. The EATC4Children works to support opportunities and efforts to translate findings from basic laboratory studies to the establishment of biomarkers, new therapeutic targets, and agents identified in the adult-disease groups into the “first in childhood disease” arena.
The EATC4Children research focus centres around:
- Novel therapies identified and developed through strategic partnerships with UK adult-based experimental medicine and early phase clinical trial infrastructure
- Early phase trials in each disease focus as part of Paediatric Investigation Plans, and diagnostic/prognostic biomarker validation for future clinical trials
- Experimental medicine/preclinical studies arising from preliminary data, including prognostic biomarker development.
We recognise the importance of making sure that children with arthritis benefit from the enormous improvements in treatment that have emerged in the past decade.Professor Alan Silman, Medical Director of Arthritis Research UK