Photo of Em P Jon Rhodes

Em P Jon Rhodes MA, MD, FRCP, FMedSci

Emeritus Professor of Medicine and Honorary Senior Research Fellow Cellular and Molecular Physiology

Research

Research Grants

MECNUT: Impact of dietary exposure to emulsifiers on the intestinal mucosa - implications for inflammatory bowel disease and metabolic syndrome

MEDICAL RESEARCH COUNCIL (MRC)

November 2017 - March 2021

Investigating bacteria-induced Wnt signalling as a mechanism for malignant development in the gut epithelium.

NORTH WEST CANCER RESEARCH FUND

September 2013 - September 2016

Evaluation of novel therapies targeting adhesive/invasive E.Coli

DEPARTMENT OF HEALTH (UK) (NIHR)

November 2007 - March 2012

Characterization of the endothelial cell surface molecule(s) responsible for galectin-3-induced secretion of metastasis-promoting cytokines

NORTH WEST CANCER RESEARCH FUND, NORTH WEST CANCER RESEARCH INCORPORATING CLATTERBRIDGE CANCER RESEARCH (UK)

July 2014 - March 2017

Experiments to characterise the interaction between inflammatory bowel disease-related bacteria and mucosal glycoconjugates.

NAT ASSOC FOR COLITIS & CROHNS DISEASE (UK)

October 1999 - September 2002

The potential role of soluble plantain fibre and its components in preventing colonisation and invasion of the intestinal mucosa by S.Typhimurium.

BIOTECHNOLOGY & BIOLOGICAL SCIENCE RESEARCH COUNCIL (BBSRC)

October 2009 - December 2012

Prospective registry of inflammatory bowel diseases

ROYAL LIVERPOOL AND BROADGREEN UNIVERSITY HOSPITALS NHS TRUST (UK)

September 2010 - August 2011

Mucosa-associated bacteria and human colon cancer.

ROYAL LIVERPOOL AND BROADGREEN UNIVERSITY HOSPITALS NHS TRUST (UK)

October 2005 - September 2007

Trial of antibiotics and hydroxychloroquine in Crohn's disease

NAT ASSOC FOR COLITIS & CROHNS DISEASE (UK)

October 2013 - March 2020

Bacterial oligomannan as a cause of intramucosal neutrophil dysfunction in Crohn's Disease.

ROYAL LIVERPOOL AND BROADGREEN UNIVERSITY HOSPITALS NHS TRUST (UK)

April 2001 - March 2003

Bacterial oligomannan as a cause of intramucosal neutrophil dysfunction in Chrohn's disease.

DIGESTIVE DISORDERS FOUNDATION

February 2001 - January 2003

Investigation into the mechanisms by which the galactose-binding lectin in mushrooms affects proliferation in colon cancer cells.

WORLD CANCER RESEARCH FUND (UK)

December 1999 - November 2002

Identification and functional characterization of the jacalin-binding cell membrane protein that regulates tyrosine phosphorylation of tumour suppressor PHAPI/pp32.

NORTH WEST CANCER RESEARCH FUND

October 2006 - September 2009

Tumour suppressing activity of Sclerotium rolfsii lectin on colon cancer

UK-INDIA EDUCATION AND RESEARCH INITIATIVE (UK)

January 2009 - December 2012

Cellular Biology of the Gastrointestinal Tract and Pancreas in Health and Disease.

MEDICAL RESEARCH COUNCIL (MRC)

January 2000 - December 2004

Identifying the molecular mechanisms of interaction between colonic Crohn's disease mucosa-associated Escherichia coli and the intestinal epithelium

NAT ASSOC FOR COLITIS & CROHNS DISEASE (UK)

May 2008 - April 2010

Glycobiology: Interactions of Lectins with tumor cell surface molecule.

ASSOCIATION OF COMMONWEALTH UNIVERSITIES (UK)

October 2006 - April 2007

Studies to characterise the intracellular ligands for the anti-proliferative mushroom lectin in colon cancer cells.

NORTH WEST CANCER RESEARCH FUND

June 1999 - June 2002

Characterising the molecular mechanisms of Crohn's disease associated Escherichia coli that enable their survival and replication within the macrophage phagolysosome

MINISTRY OF HIGHER EDUCATION (LIBYA)

February 2013 - January 2016

Systems medicine of chronic inflammatory bowel disease (SysmedIBD)

EUROPEAN COMMISSION

December 2012 - November 2017

Mucins in the pathophysiology of inflammatory diseases of the bronchial and gastrointestinal epithelia.

MEDICAL RESEARCH COUNCIL (MRC)

April 1998 - March 2001

Studies in inflammatory bowel disease.

ROYAL LIVERPOOL AND BROADGREEN UNIVERSITY HOSPITALS NHS TRUST (UK)

January 2002 - June 2002

The effects of dietry Gal-GalNAc-binding lectins on intestinal epithelial metabolism and proliferation.

BIOTECHNOLOGY & BIOLOGICAL SCIENCE RESEARCH COUNCIL (BBSRC)

December 1997 - May 2001

Investigation of IL-8 release by mucosally-adherent E. coli and bacteroides species relevant to pathogensis of inflammatory bowel disease.

NAT ASSOC FOR COLITIS & CROHNS DISEASE (UK)

September 2003 - September 2005

Macrophage dysfunction in the pathogenesis of Crohn's disease.

MEDICAL RESEARCH COUNCIL (MRC)

February 2003 - January 2006

Cellular biology of the gastrointestinal tract and pancreas in health and disease.

MEDICAL RESEARCH COUNCIL (MRC)

January 2005 - December 2009

The role of Adherent, Invasive Escherichia coli in the pathogenesis of Crohn's disease: Evaluation of new therapeutic approaches targeting E.coli replicating within the macrophage phagolysosome

ROYAL LIVERPOOL AND BROADGREEN UNIVERSITY HOSPITALS NHS TRUST (UK)

April 2012 - March 2013

Assessment of the functional impact of Crohn's associated genetic polymorphisms

SHIRE PHARMACEUTICAL DEVELOPMENT INC (USA)

February 2012 - March 2013