Mrs Claire Lucas PhD

Scientist and Honorary Lecturer Molecular & Clinical Cancer Medicine

    Publications

    Selected Publications

    1. Second generation tyrosine kinase inhibitors prevent disease progression in high-risk (high CIP2A) chronic myeloid leukaemia patients (Journal article - 2015)
    2. C-Myc inhibition decreases CIP2A and reduces BCR-ABL1 tyrosine kinase activity in chronic myeloid leukemia (Journal article - 2015)
    3. A population study showing that the advent of second generation tyrosine kinase inhibitors has improved progression-free survival in chronic myeloid leukaemia. (Journal article - 2013)
    4. Cancerous inhibitor of PP2A (CIP2A) at diagnosis of chronic myeloid leukemia is a critical determinant of disease progression (Journal article - 2011)
    5. High CIP2A levels correlate with an antiapoptotic phenotype that can be overcome by targeting BCL-X-L in chronic myeloid leukemia (Journal article - 2016)