Professor Judy Coulson PhD

Professor Molecular Physiology & Cell Signalling

    Research

    Roles of reversible ubiquitination in cell signalling, cell cycle and transcription.



    Transcriptional regulation in lung cancer.

    Translational research in mesothelioma and lung cancer

    Research Grants

    Developing a chick embryo model to aid in development of personalised therapies for malignant pleural mesothelioma

    NATIONAL CENTRE FOR THE REP, REF AND RED OF ANIMALS USED IN RESEARCH (NC3RS)

    November 2019 - January 2023

    Integrative analysis of BAP1-dependencies to identify novel therapeutic targets for uveal melanoma: learning lessons from the lung

    FIGHT FOR SIGHT (UK)

    October 2019 - December 2022

    Translating discovery science: DUBs that regulate centrosome clustering, an Achilles' heel of cancer

    BREAST CANCER NOW (UK)

    October 2019 - September 2023

    The Role of Reversible Ubiquitination in Virus Infection

    ROYAL EMBASSY OF SAUDI ARABIA CULTURAL BUREAU IN LONDON (UK)

    October 2016 - September 2020

    Translating BAP1 dependencies for precision therapy of mesothelioma

    BRITISH LUNG FOUNDATION (UK)

    March 2017 - March 2021

    Wellcome Trust Four-Year PhD Studentship with the Cellular and Molecular Physiology PhD Programme

    WELLCOME TRUST (UK)

    October 2015 - September 2019

    Mechanistic study of the reduction of RBM4 in cancer and its role in regulating the oncogenic SRSF1

    DEPARTMENT FOR BUSINESS, INNOVATION AND SKILLS (UK)

    March 2015 - March 2018

    Investigating in vivo resistance mechanisms to MEK inhibitors in uveal melanoma to enable novel combinatorial therapies.

    NORTH WEST CANCER RESEARCH INCORPORATING CLATTERBRIDGE CANCER RESEARCH - NWCR (UK)

    March 2016 - May 2019

    S18-phosphorylation controls catalytic activity of the cancer-associated deubiquitylase USP7: defining the implications for cancer biology and USP7 inhibitor therapy

    NORTH WEST CANCER RESEARCH INCORPORATING CLATTERBRIDGE CANCER RESEARCH - NWCR (UK)

    October 2016 - December 2019

    Wellcome trust four-year PhD studentship with the cellular and molecular physiology PhD programme

    WELLCOME TRUST (UK)

    October 2012 - September 2016

    Wellcome Trust Four-Year PhD Studentship with the Cellular and Molecular Physiology Programme

    WELLCOME TRUST (UK)

    October 2011 - March 2016

    Regulation and substrate-specificity for isoforms of the debiquitinase USP15 during the cell cycle

    NORTH WEST CANCER RESEARCH FUND

    February 2013 - February 2015

    Isogenic cell lines for targeted therapy discovery and development in BAP1-deficient mesothelioma

    BRITISH LUNG FOUNDATION (UK)

    October 2012 - January 2016

    Targeting an Achilles’ heel of cancer: Deubiquitylases as novel targets for centrosome de-clustering and cancer-cell specific cell death

    NORTH WEST CANCER RESEARCH INCORPORATING CLATTERBRIDGE CANCER RESEARCH - NWCR (UK)

    March 2015 - February 2018

    Wellcome Trust four year PhD studentship with the Cellular and Molecular Physiology Programme

    WELLCOME TRUST (UK)

    October 2013 - September 2017

    Novel isogenic models of BAP1-deficient uveal melanoma for drug discovery

    FIGHT FOR SIGHT (UK)

    October 2014 - September 2018