Professor Judy Coulson PhD

Professor Molecular & Physiology Cell Signalling

    Publications

    Selected Publications

    1. Loss of the deubiquitylase BAP1 alters class I histone deacetylase expression and sensitivity of mesothelioma cells to HDAC inhibitors (Journal article - 2015)
    2. The deubiquitylase Ataxin-3 restricts PTEN transcription in lung cancer cells (Journal article - 2014)
    3. Cellular functions of the DUBs (Journal article - 2012)
    4. SCG3 Transcript in Peripheral Blood Is a Prognostic Biomarker for REST-Deficient Small Cell Lung Cancer (Journal article - 2009)
    5. A splice variant of the neuron-restrictive silencer factor repressor is expressed in small cell lung cancer: A potential role in derepression of neuroendocrine genes and a useful clinical marker (Journal article - 2000)

    2020

    Loss of BAP1 expression is associated with an immunosuppressive microenvironment in uveal melanoma, with implications for immunotherapy development. (Journal article)

    Figueiredo, C. R., Kalirai, H., Sacco, J. J., Azevedo, R. A., Duckworth, A., Slupsky, J. R., . . . Coupland, S. E. (2020). Loss of BAP1 expression is associated with an immunosuppressive microenvironment in uveal melanoma, with implications for immunotherapy development.. The Journal of Pathology, 250(4), 420-439. doi:10.1002/path.5384

    DOI: 10.1002/path.5384

    2019

    Targeting centrosome amplification, an Achilles' heel of cancer (Journal article)

    Sabat-Pospiech, D., Fabian-Kolpanowicz, K., Prior, I. A., Coulson, J. M., & Fielding, A. B. (2019). Targeting centrosome amplification, an Achilles' heel of cancer. BIOCHEMICAL SOCIETY TRANSACTIONS, 47, 1209-1222. doi:10.1042/BST20190034

    DOI: 10.1042/BST20190034

    Isoform-specific Ras signaling is growth factor dependent (Journal article)

    Hood, F. E., Klinger, B., Newlaczyl, A. U., Sieber, A., Dorel, M., Oliver, S. P., . . . Prior, I. A. (2019). Isoform-specific Ras signaling is growth factor dependent. Molecular biology of the cell, 30(9), 1108-1117. doi:10.1091/mbc.e18-10-0676

    DOI: 10.1091/mbc.e18-10-0676

    2018

    SRSF1 modulates PTPMT1 alternative splicing to regulate lung cancer cell radioresistance (Journal article)

    Sheng, J., Zhao, Q., Zhao, J., Zhang, W., Sun, Y., Qin, P., . . . Wang, Y. (2018). SRSF1 modulates PTPMT1 alternative splicing to regulate lung cancer cell radioresistance. EBioMedicine, 38, 113-126. doi:10.1016/j.ebiom.2018.11.007

    DOI: 10.1016/j.ebiom.2018.11.007

    RAS variant signalling (Journal article)

    Mo, S. P., Coulson, J. M., & Prior, I. A. (2018). RAS variant signalling. BIOCHEMICAL SOCIETY TRANSACTIONS, 46, 1325-1332. doi:10.1042/BST20180173

    DOI: 10.1042/BST20180173

    Altered Nuclear Expression of the Deubiquitylase BAP1 Cannot be Used as a Prognostic Marker for Canine Melanoma (Journal article)

    Jama, N., Farquhar, N., Butt, Z., Coupland, S. E., Sacco, J. J., Scase, T., . . . Killick, D. R. (2018). Altered Nuclear Expression of the Deubiquitylase BAP1 Cannot be Used as a Prognostic Marker for Canine Melanoma. Journal of Comparative Pathology, 162, 50-58. doi:10.1016/j.jcpa.2018.06.007

    DOI: 10.1016/j.jcpa.2018.06.007

    Recent breakthroughs in metastatic uveal melanoma: a cause for optimism? (Journal article)

    Sacco, J. J., Kalirai, H., Kenyani, J., Figueiredo, C. R., Coulson, J. M., & Coupland, S. E. (2018). Recent breakthroughs in metastatic uveal melanoma: a cause for optimism?. FUTURE ONCOLOGY, 14(14), 1335-1338. doi:10.2217/fon-2018-0116

    DOI: 10.2217/fon-2018-0116

    The deubiquitylase USP15 regulates topoisomerase II alpha to maintain genome integrity (Journal article)

    Fielding, A. B., Concannon, M., Darling, S., Rusilowicz, E., Sacco, J., Prior, I. A., . . . Coulson, J. M. (2018). The deubiquitylase USP15 regulates topoisomerase II alpha to maintain genome integrity. Oncogene, 37(17), 2326-2342. doi:10.1038/s41388-017-0092-0

    DOI: 10.1038/s41388-017-0092-0

    Kinome-wide transcriptional profiling of uveal melanoma reveals new vulnerabilities to targeted therapeutics (Journal article)

    Bailey, F. P., Clarke, K., Kalirai, H., Kenyani, J., Shahidipour, H., Falciani, F., . . . Eyers, P. A. (2018). Kinome-wide transcriptional profiling of uveal melanoma reveals new vulnerabilities to targeted therapeutics. Pigment Cell and Melanoma Research, 31(2), 253-266. doi:10.1111/pcmr.12650

    DOI: 10.1111/pcmr.12650

    New Perspectives, Opportunities, and Challenges in Exploring the Human Protein Kinome (Journal article)

    Wilson, L. J., Linley, A., Hammond, D. E., Hood, F. E., Coulson, J. M., MacEwan, D. J., . . . Prior, I. A. (2018). New Perspectives, Opportunities, and Challenges in Exploring the Human Protein Kinome. CANCER RESEARCH, 78(1), 15-29. doi:10.1158/0008-5472.CAN-17-2291

    DOI: 10.1158/0008-5472.CAN-17-2291

    Patterns of BAP1 protein expression provide insights into prognostic significance and the biology of uveal melanoma (Journal article)

    Farquhar, N., Thornton, S., Coupland, S. E., Coulson, J., Sacco, J. J., Krishna, Y., . . . Kalirai, H. (2018). Patterns of BAP1 protein expression provide insights into prognostic significance and the biology of uveal melanoma. The Journal of Pathology: Clinical Research, 4(1), 26-38. doi:10.1002/cjp2.86

    DOI: 10.1002/cjp2.86

    2017

    Regulation of the cell cycle and centrosome biology by deubiquitylases (Journal article)

    Darling, S., Fielding, A. B., Sabat-Pospiech, D., Prior, I. A., & Coulson, J. M. (2017). Regulation of the cell cycle and centrosome biology by deubiquitylases. BIOCHEMICAL SOCIETY TRANSACTIONS, 45, 1125-1136. doi:10.1042/BST20170087

    DOI: 10.1042/BST20170087

    Quantification of spatiotemporal patterns of Ras isoform expression during development (Journal article)

    Newlaczyl, A. U., Coulson, J. M., & Prior, I. A. (2017). Quantification of spatiotemporal patterns of Ras isoform expression during development. Scientific reports, 7. doi:10.1038/srep41297

    DOI: 10.1038/srep41297

    Transcriptomic and Epigenetic Regulation of Disuse Atrophy and the Return to Activity in Skeletal Muscle (Journal article)

    Fisher, A. G., Seaborne, R. A., Hughes, T. M., Gutteridge, A., Stewart, C., Coulson, J. M., . . . Jarvis, J. (2017). Transcriptomic and Epigenetic Regulation of Disuse Atrophy and the Return to Activity in Skeletal Muscle. The FASEB Journal, 31(12), 5268-5282. doi:10.1096/fj.201700089RR

    DOI: 10.1096/fj.201700089RR

    2016

    Transcription Factors Regulating Neuroendocrine Development, Function, and Oncogenesis (Chapter)

    Coulson, J. M., & Concannon, M. (n.d.). Transcription Factors Regulating Neuroendocrine Development, Function, and Oncogenesis. In Molecular Neuroendocrinology (pp. 97-120). John Wiley & Sons, Ltd. doi:10.1002/9781118760369.ch5

    DOI: 10.1002/9781118760369.ch5

    2015

    Combined Analyses of the VHL and Hypoxia Signaling Axes in an Isogenic Pairing of Renal Clear Cell Carcinoma Cells (Journal article)

    Malec, V., Coulson, J. M., Urbe, S., & Clague, M. J. (2015). Combined Analyses of the VHL and Hypoxia Signaling Axes in an Isogenic Pairing of Renal Clear Cell Carcinoma Cells. JOURNAL OF PROTEOME RESEARCH, 14(12), 5263-5272. doi:10.1021/acs.jproteome.5b00692

    DOI: 10.1021/acs.jproteome.5b00692

    Loss of the deubiquitylase BAP1 alters class I histone deacetylase expression and sensitivity of mesothelioma cells to HDAC inhibitors (Journal article)

    Sacco, J., Kenyani, J., Butt, Z., Carter, R., Chew, H. Y., Cheeseman, L. P., . . . Coulson, J. (2015). Loss of the deubiquitylase BAP1 alters class I histone deacetylase expression and sensitivity of mesothelioma cells to HDAC inhibitors. Oncotarget, 6(15), 13757-13771. doi:10.18632/oncotarget.3765

    DOI: 10.18632/oncotarget.3765

    2014

    Plasticity of Mammary Cell Boundaries Governed by EGF and Actin Remodeling (Journal article)

    Tang, W. Y., Beckett, A., Prior, I., Coulson, J., Urbe, S., & Clague, M. (2014). Plasticity of Mammary Cell Boundaries Governed by EGF and Actin Remodeling. Cell Reports, 8(06), 1722-1730. doi:10.1016/j.celrep.2014.08.026

    DOI: 10.1016/j.celrep.2014.08.026

    The deubiquitylase Ataxin-3 restricts PTEN transcription in lung cancer cells (Journal article)

    Sacco, J., Yau, T. Y., Darling, S., Patel, V., Liu, H., Urbe, S., . . . Coulson, J. (2014). The deubiquitylase Ataxin-3 restricts PTEN transcription in lung cancer cells. Oncogene, 33(33), 4265-4272. doi:10.1038/onc.2013.512

    DOI: 10.1038/onc.2013.512

    Decoding RAS isoform and codon-specific signalling (Journal article)

    Newlaczyl, A. U., Hood, F. E., Coulson, J. M., & Prior, I. A. (2014). Decoding RAS isoform and codon-specific signalling. BIOCHEMICAL SOCIETY TRANSACTIONS, 42, 742-746. doi:10.1042/BST20140057

    DOI: 10.1042/BST20140057

    2013

    Deubiquitylases From Genes to Organism (Journal article)

    Clague, M. J., Barsukov, I., Coulson, J. M., Liu, H., Rigden, D. J., & Urbé, S. (2013). Deubiquitylases From Genes to Organism. Physiological Reviews, 93(3), 1289-1315. doi:10.1152/physrev.00002.2013

    DOI: 10.1152/physrev.00002.2013

    The deubiquitylase USP15 stabilizes newly synthesized REST and rescues its expression at mitotic exit (Journal article)

    Faronato, M., Patel, V., Darling, S., Dearden, L., Clague, M. J., Urbe, S., & Coulson, J. M. (2013). The deubiquitylase USP15 stabilizes newly synthesized REST and rescues its expression at mitotic exit. CELL CYCLE, 12(12), 1964-1977. doi:10.4161/cc.25035

    DOI: 10.4161/cc.25035

    Plasticity of mammary cell boundaries governed by EGF (Journal article)

    Tang, Y., Beckett, A. J., Prior, I. A., Coulson, J. M., Urbe, S., & Clague, M. J. (2013). Plasticity of mammary cell boundaries governed by EGF. MOLECULAR BIOLOGY OF THE CELL, 24. Retrieved from http://gateway.webofknowledge.com/

    2012

    Direct and Indirect Control of Mitogen-activated Protein Kinase Pathway-associated Components, BRAP/IMP E3 Ubiquitin Ligase and CRAF/RAF1 Kinase, by the Deubiquitylating Enzyme USP15 (Journal article)

    Hayes, S. D., Liu, H., MacDonald, E., Sanderson, C. M., Coulson, J. M., Clague, M. J., & Urbe, S. (2012). Direct and Indirect Control of Mitogen-activated Protein Kinase Pathway-associated Components, BRAP/IMP E3 Ubiquitin Ligase and CRAF/RAF1 Kinase, by the Deubiquitylating Enzyme USP15. JOURNAL OF BIOLOGICAL CHEMISTRY, 287(51), 43007-43018. doi:10.1074/jbc.M112.386938

    DOI: 10.1074/jbc.M112.386938

    Cellular functions of the DUBs (Journal article)

    Clague, M. J., Coulson, J. M., & Urbe, S. (2012). Cellular functions of the DUBs. JOURNAL OF CELL SCIENCE, 125(2), 277-286. doi:10.1242/jcs.090985

    DOI: 10.1242/jcs.090985

    2011

    Isoform-Specific Localization of the Deubiquitinase USP33 to the Golgi Apparatus (Journal article)

    Thorne, C., Eccles, R. L., Coulson, J. M., Urbé, S., & Clague, M. J. (2011). Isoform-Specific Localization of the Deubiquitinase USP33 to the Golgi Apparatus. Traffic, 12(11), 1563-1574. doi:10.1111/j.1600-0854.2011.01261.x

    DOI: 10.1111/j.1600-0854.2011.01261.x

    REST (RE1-silencing transcription factor) (Journal article)

    Faronato, M., & Coulson, J. M. (n.d.). REST (RE1-silencing transcription factor). Atlas of Genetics and Cytogenetics in Oncology and Haematology, (2). doi:10.4267/2042/44968

    DOI: 10.4267/2042/44968

    USP15 (ubiquitin specific peptidase 15) (Journal article)

    Faronato, M., Urbé, S., & Coulson, J. M. (n.d.). USP15 (ubiquitin specific peptidase 15). Atlas of Genetics and Cytogenetics in Oncology and Haematology, (8). doi:10.4267/2042/46013

    DOI: 10.4267/2042/46013

    2010

    Emerging roles of deubiquitinases in cancer-associated pathways (Journal article)

    Sacco, J. J., Coulson, J. M., Clague, M. J., & Urbé, S. (2010). Emerging roles of deubiquitinases in cancer-associated pathways. IUBMB Life, NA. doi:10.1002/iub.300

    DOI: 10.1002/iub.300

    2009

    Reduction in RNA Levels Rather than Retardation of Translation Is Responsible for the Inhibition of Major Histocompatibility Complex Class I Antigen Presentation by the Glutamic Acid-Rich Repeat of Herpesvirus Saimiri Open Reading Frame 73 (Journal article)

    Gao, J., Coulson, J. M., Whitehouse, A., & Blake, N. (2009). Reduction in RNA Levels Rather than Retardation of Translation Is Responsible for the Inhibition of Major Histocompatibility Complex Class I Antigen Presentation by the Glutamic Acid-Rich Repeat of Herpesvirus Saimiri Open Reading Frame 73. JOURNAL OF VIROLOGY, 83(1), 273-282. doi:10.1128/JVI.01532-08

    DOI: 10.1128/JVI.01532-08

    SCG3 Transcript in Peripheral Blood Is a Prognostic Biomarker for REST-Deficient Small Cell Lung Cancer (Journal article)

    Moss, A. C., Jacobson, G. M., Walker, L. E., Blake, N. W., Marshall, E., & Coulson, J. M. (2009). SCG3 Transcript in Peripheral Blood Is a Prognostic Biomarker for REST-Deficient Small Cell Lung Cancer. CLINICAL CANCER RESEARCH, 15(1), 274-283. doi:10.1158/1078-0432.CCR-08-1163

    DOI: 10.1158/1078-0432.CCR-08-1163

    2008

    Real-time polymerase chain reaction to follow the response of muscle to training (Journal article)

    Moore, L. M., Fisher, A. G., Coulson, J. M., Salmons, S., & Jarvis, J. C. (2008). Real-time polymerase chain reaction to follow the response of muscle to training. ARTIFICIAL ORGANS, 32(8), 630-633. doi:10.1111/j.1525-1594.2008.00613.x

    DOI: 10.1111/j.1525-1594.2008.00613.x

    Deciphering histone 2A deubiquitination (Journal article)

    Clague, M. J., Coulson, J. M., & Urbe, S. (2008). Deciphering histone 2A deubiquitination. GENOME BIOLOGY, 9(1). doi:10.1186/gb-2008-9-1-202

    DOI: 10.1186/gb-2008-9-1-202

    2007

    Targeting tumour cells with defects in the MHC Class I antigen processing pathway with CD8+ T cells specific for hydrophobic TAP- and Tapasin-independent peptides: the requirement for directed access into the ER (Journal article)

    Aladin, F., Lautscham, G., Humphries, E., Coulson, J., & Blake, N. (2007). Targeting tumour cells with defects in the MHC Class I antigen processing pathway with CD8+ T cells specific for hydrophobic TAP- and Tapasin-independent peptides: the requirement for directed access into the ER. CANCER IMMUNOLOGY IMMUNOTHERAPY, 56(8), 1143-1152. doi:10.1007/s00262-006-0263-2

    DOI: 10.1007/s00262-006-0263-2

    2006

    Site-specific phosphorylation of SCG10 in neuronal plasticity: Role of Ser73 phosphorylation by N-methyl D-aspartic acid receptor activation in rat hippocampus (Journal article)

    Morii, H., Yamada, T., Nakano, I., Coulson, J. M., & Mori, N. (2006). Site-specific phosphorylation of SCG10 in neuronal plasticity: Role of Ser73 phosphorylation by N-methyl D-aspartic acid receptor activation in rat hippocampus. NEUROSCIENCE LETTERS, 396(3), 241-246. doi:10.1016/j.neulet.2005.11.043

    DOI: 10.1016/j.neulet.2005.11.043

    Regulation and role of REST and REST4 variants in modulation of gene expression in in vivo and in vitro in epilepsy models (Journal article)

    Spencer, E. M., Chandler, K. E., Haddley, K., Howard, M. R., Hughes, D., Belyaev, N. D., . . . Quinn, J. P. (2006). Regulation and role of REST and REST4 variants in modulation of gene expression in in vivo and in vitro in epilepsy models. NEUROBIOLOGY OF DISEASE, 24(1), 41-52. doi:10.1016/j.nbd.2006.04.020

    DOI: 10.1016/j.nbd.2006.04.020

    2005

    Transcriptional regulation: Cancer, neurons and the REST (Journal article)

    Coulson, J. M. (2005). Transcriptional regulation: Cancer, neurons and the REST. CURRENT BIOLOGY, 15(17), R665-R668. doi:10.1016/j.cub.2005.08.032

    DOI: 10.1016/j.cub.2005.08.032

    Roles for USF-2 in lung cancer proliferation and bronchial carcinogenesis (Journal article)

    Ocejo-Garcia, M., Baokbah, T. A. S., Ashurst, H. L., Cowlishaw, D., Soomro, I., Coulson, J. M., & Woll, P. J. (2005). Roles for USF-2 in lung cancer proliferation and bronchial carcinogenesis. JOURNAL OF PATHOLOGY, 206(2), 151-159. doi:10.1002/path.1775

    DOI: 10.1002/path.1775

    2004

    Regulation of the cell-specific calcitonin/calcitonin gene-related peptide enhancer by USF and the Foxa2 forkhead protein (Journal article)

    Viney, T. J., Schmidt, T. W., Gierasch, W., Sattar, A. W., Yaggie, R. E., Kuburas, A., . . . Russo, A. F. (2004). Regulation of the cell-specific calcitonin/calcitonin gene-related peptide enhancer by USF and the Foxa2 forkhead protein. JOURNAL OF BIOLOGICAL CHEMISTRY, 279(48), 49948-49955. doi:10.1074/jbc.M406659200

    DOI: 10.1074/jbc.M406659200

    Genetic abnormalities in plasma DNA of patients with lung cancer and other respiratory diseases (Journal article)

    Khan, S., Coulson, J. M., & Woll, P. J. (2004). Genetic abnormalities in plasma DNA of patients with lung cancer and other respiratory diseases. INTERNATIONAL JOURNAL OF CANCER, 110(6), 891-895. doi:10.1002/ijc.20156

    DOI: 10.1002/ijc.20156

    Overexpression of cyclooxygenase-2 in non-small cell lung cancer (Journal article)

    Petkova, D. K., Clelland, C., Ronan, J., Pang, L., Coulson, J. M., Lewis, S., & Knox, A. J. (2004). Overexpression of cyclooxygenase-2 in non-small cell lung cancer. RESPIRATORY MEDICINE, 98(2), 164-172. doi:10.1016/j.rmed.2003.09.006

    DOI: 10.1016/j.rmed.2003.09.006

    2003

    Cross-talk between hypoxic and circadian pathways: cooperative roles for hypoxia-inducible factor 1 alpha and CLOCK in transcriptional activation of the vasopressin gene (Journal article)

    Ghorbel, M. T., Coulson, J. M., & Murphy, D. (2003). Cross-talk between hypoxic and circadian pathways: cooperative roles for hypoxia-inducible factor 1 alpha and CLOCK in transcriptional activation of the vasopressin gene. MOLECULAR AND CELLULAR NEUROSCIENCE, 22(3), 396-404. doi:10.1016/S1044-7431(02)00019-2

    DOI: 10.1016/S1044-7431(02)00019-2

    Upstream stimulatory factor activates the vasopressin promoter via multiple motifs, including a non-canonical E-box (Journal article)

    Coulson, J. M., Edgson, J. L., Marshal-Jones, Z. V., Mulgrew, R., Quinn, J. P., & Woll, P. J. (2003). Upstream stimulatory factor activates the vasopressin promoter via multiple motifs, including a non-canonical E-box. BIOCHEMICAL JOURNAL, 369, 549-561. doi:10.1042/BJ20021176

    DOI: 10.1042/BJ20021176

    Detection of small cell lung cancer by RT-PCR for neuropeptides, neuropeptide receptors, or a splice variant of the neuron restrictive silencer factor. (Journal article)

    Coulson, J. M., Ahmed, S. I., Quinn, J. P., & Woll, P. J. (2003). Detection of small cell lung cancer by RT-PCR for neuropeptides, neuropeptide receptors, or a splice variant of the neuron restrictive silencer factor.. Methods in molecular medicine, 75, 335-352. doi:10.1385/1-59259-324-0:335

    DOI: 10.1385/1-59259-324-0:335

    Detection of small cell lung cancer by RT-PCR for neuropeptides, neuropeptide receptors, or a splice variant of the neuron restrictive silencer factor. (Chapter)

    Coulson, J. M., Ahmed, S. I., Quinn, J. P., & Woll, P. J. (2003). Detection of small cell lung cancer by RT-PCR for neuropeptides, neuropeptide receptors, or a splice variant of the neuron restrictive silencer factor.. In B. Driscoll (Ed.), Lung Cancer Volume 2: Diagnostic and Therapeutic Methods and Reviews (Vol. 75, pp. 335-352). New Jersey: Humana Press.

    Neuroendocrine phenotype of small cell lung cancer. (Chapter)

    Coulson, J. M., Ocejo-Garcia, M., & Woll, P. J. (2003). Neuroendocrine phenotype of small cell lung cancer.. In Unknown Book (Vol. 74, pp. 61-73). doi:10.1385/1-59259-323-2:61

    DOI: 10.1385/1-59259-323-2:61

    2002

    Neuron restrictive silencer factor as a modulator of neuropeptide gene expression (Journal article)

    Quinn, J. P., Bubb, V. J., Marshall-Jones, Z. V., & Coulson, J. M. (2002). Neuron restrictive silencer factor as a modulator of neuropeptide gene expression. REGULATORY PEPTIDES, 108(2-3), 135-141. doi:10.1016/S0167-0115(02)00103-9

    DOI: 10.1016/S0167-0115(02)00103-9

    Chapter 26 Positive and negative regulators of the vasopressin gene promoter in small cell lung cancer (Chapter)

    Coulson, J. M. (2002). Chapter 26 Positive and negative regulators of the vasopressin gene promoter in small cell lung cancer. In Vasopressin and Oxytocin: From Genes to Clinical Applications (pp. 329-343). Elsevier. doi:10.1016/s0079-6123(02)39028-9

    DOI: 10.1016/s0079-6123(02)39028-9

    Neuron restrictive silencer factor as a modulator of neuropeptide gene expression. (Journal article)

    Quinn, J. P., Bubb, V. J., Marshall-Jones, Z. V., & Coulson, J. M. (2002). Neuron restrictive silencer factor as a modulator of neuropeptide gene expression.. Regulatory Peptides, 108(2-3), 1-9.

    Positive and negative regulators of the vasopressin gene promoter in small cell lung cancer (Chapter)

    Coulson, J. M. (2002). Positive and negative regulators of the vasopressin gene promoter in small cell lung cancer. In Unknown Book (Vol. 139, pp. 329-343). Retrieved from http://gateway.webofknowledge.com/

    2001

    Use of RT-PCR to detect co-expression of neuropeptides and their receptors in lung cancer (Journal article)

    Ocejo-Garcia, M., Ahmed, S. I., Coulson, J. M., & Woll, P. J. (2001). Use of RT-PCR to detect co-expression of neuropeptides and their receptors in lung cancer. LUNG CANCER, 33(1), 1-9. doi:10.1016/S0169-5002(00)00248-8

    DOI: 10.1016/S0169-5002(00)00248-8

    2000

    A splice variant of the neuron-restrictive silencer factor repressor is expressed in small cell lung cancer: A potential role in derepression of neuroendocrine genes and a useful clinical marker (Journal article)

    Coulson, J. M., Edgson, J. L., Woll, P. J., & Quinn, J. P. (2000). A splice variant of the neuron-restrictive silencer factor repressor is expressed in small cell lung cancer: A potential role in derepression of neuroendocrine genes and a useful clinical marker. CANCER RESEARCH, 60(7), 1840-1844. Retrieved from http://gateway.webofknowledge.com/

    Studies on the expression of endothelin, its receptor subtypes, and converting enzymes in lung cancer and in human bronchial epithelium (Journal article)

    Ahmed, S. I., Thompson, J., Coulson, J. M., & Woll, P. J. (2000). Studies on the expression of endothelin, its receptor subtypes, and converting enzymes in lung cancer and in human bronchial epithelium. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY, 22(4), 422-431. doi:10.1165/ajrcmb.22.4.3795

    DOI: 10.1165/ajrcmb.22.4.3795

    1999

    E-box motifs within the human vasopressin gene promoter contribute to a major enhancer in small-cell lung cancer (Journal article)

    Coulson, J. M., Fiskerstrand, C. E., Woll, P. J., & Quinn, J. P. (1999). E-box motifs within the human vasopressin gene promoter contribute to a major enhancer in small-cell lung cancer. BIOCHEMICAL JOURNAL, 344, 961-970. doi:10.1042/0264-6021:3440961

    DOI: 10.1042/0264-6021:3440961

    Arginine vasopressin promoter regulation is mediated by a neuron-restrictive silencer element in small cell lung cancer (Journal article)

    Coulson, J. M., Fiskerstrand, C. E., Woll, P. J., & Quinn, J. P. (1999). Arginine vasopressin promoter regulation is mediated by a neuron-restrictive silencer element in small cell lung cancer. CANCER RESEARCH, 59(20), 5123-5127. Retrieved from http://gateway.webofknowledge.com/

    Tumour-specific arginine vasopressin promoter activation in small-cell lung cancer (Journal article)

    Coulson, J. M., Stanley, J., & Woll, P. J. (1999). Tumour-specific arginine vasopressin promoter activation in small-cell lung cancer. BRITISH JOURNAL OF CANCER, 80(12), 1935-1944. doi:10.1038/sj.bjc.6690623

    DOI: 10.1038/sj.bjc.6690623

    Arginine Vasopressin Promoter Regulation Is Mediated by a Neuron-restrictive Silencer Element in Small Cell Lung Cancer (Journal article)

    Coulson, J. M., Fiskerstrand, C. E., Woll, P. J., & Quinn, J. P. (1999). Arginine Vasopressin Promoter Regulation Is Mediated by a Neuron-restrictive Silencer Element in Small Cell Lung Cancer. Cancer Research, (59), 5123-5127.

    1997

    A c-myc phosphorothioate oligonucleotide protects U87-MG glioblastoma cells from toxicity at high concentrations of lipofectin and streptolysin O (Journal article)

    Coulson, J. M., & Akhtar, S. (1997). A c-myc phosphorothioate oligonucleotide protects U87-MG glioblastoma cells from toxicity at high concentrations of lipofectin and streptolysin O. Pharmaceutical Sciences, 3(4), 197-201.

    1996

    An oligonucleotide which blocks EGFr tyrosine phosphorylation modulates the rapid morphological change induced by EGF stimulation of A431 cells (Journal article)

    Coulson, J. M., & Akhtar, S. (1996). An oligonucleotide which blocks EGFr tyrosine phosphorylation modulates the rapid morphological change induced by EGF stimulation of A431 cells. Pharmaceutical Sciences, 2(7), 339-343.

    Erratum: An oligonucleotide which blocks EGFr tyrosine phosphorylation modulates the rapid morphological change induced by EGF stimulation of A431 cells (Pharmaceutical Sciences (1996) 2, 7 (339-343)) (Journal article)

    Coulson, J. M., & Akhtar, S. (1996). Erratum: An oligonucleotide which blocks EGFr tyrosine phosphorylation modulates the rapid morphological change induced by EGF stimulation of A431 cells (Pharmaceutical Sciences (1996) 2, 7 (339-343)). Pharmaceutical Sciences, 2(12), 605.

    A nonantisense sequence-selective effect of a phosphorothioate oligodeoxynucleotide directed against the epidermal growth factor receptor in A431 cells (Journal article)

    Coulson, J. M., Poyner, D. R., Chantry, A., Irwin, W. J., & Akhtar, S. (1996). A nonantisense sequence-selective effect of a phosphorothioate oligodeoxynucleotide directed against the epidermal growth factor receptor in A431 cells. MOLECULAR PHARMACOLOGY, 50(2), 314-325. Retrieved from http://gateway.webofknowledge.com/

    1993

    A novd method to stabilise antisense oUgonudeotides against exonudease degradation (Journal article)

    Khan, I. M., & Coulson, J. M. (1993). A novd method to stabilise antisense oUgonudeotides against exonudease degradation. Nucleic Acids Research, 21(18), 4433. doi:10.1093/nar/21.18.4433

    DOI: 10.1093/nar/21.18.4433

    A novel method to stabilise antisense oligonucleotides against exonuclease degradation. (Journal article)

    Khan, I. M., & Coulson, J. M. (1993). A novel method to stabilise antisense oligonucleotides against exonuclease degradation.. Nucleic acids research, 21(18), 4433. doi:10.1093/nar/21.18.4433

    DOI: 10.1093/nar/21.18.4433

    A NOVEL METHOD TO STABILIZE ANTISENSE OLIGONUCLEOTIDES AGAINST EXONUCLEASE DEGRADATION (Journal article)

    KHAN, I. M., & COULSON, J. M. (1993). A NOVEL METHOD TO STABILIZE ANTISENSE OLIGONUCLEOTIDES AGAINST EXONUCLEASE DEGRADATION. NUCLEIC ACIDS RESEARCH, 21(12), 2957-2958. doi:10.1093/nar/21.12.2957

    DOI: 10.1093/nar/21.12.2957

    Erratum: A novel method to stabilise antisense oligonucleotides against exonuclease degradation (Nucleic Acids Research (1993) 21 (2957-2958)) (Journal article)

    Erratum: A novel method to stabilise antisense oligonucleotides against exonuclease degradation (Nucleic Acids Research (1993) 21 (2957-2958)) (1993). Nucleic Acids Research, 21(18), 4433.

    1992

    APPLICATIONS OF ANTISENSE OLIGODEOXYNUCLEOTIDES IN VIROLOGY (Conference Paper)

    MALCOLM, A. D. B., COULSON, J., BLAKE, N., & ARCHARD, L. C. (1992). APPLICATIONS OF ANTISENSE OLIGODEOXYNUCLEOTIDES IN VIROLOGY. In BIOCHEMICAL SOCIETY TRANSACTIONS Vol. 20 (pp. 762-764). doi:10.1042/bst0200762

    DOI: 10.1042/bst0200762

    Antisense oligodeoxynucleotides as antiviral agents. (Conference Paper)

    Coulson, J. M., Blake, N. W., Archard, L. C., & Malcolm, A. D. (1992). Antisense oligodeoxynucleotides as antiviral agents.. In Biochemical Society transactions Vol. 20 (pp. 321S). doi:10.1042/bst020321s

    DOI: 10.1042/bst020321s

    ANTISENSE OLIGONUCLEOTIDES AS ANTIVIRAL AGENTS (Journal article)

    COULSON, J., & MALCOLM, A. D. B. (1992). ANTISENSE OLIGONUCLEOTIDES AS ANTIVIRAL AGENTS. ANNALS OF THE NEW YORK ACADEMY OF SCIENCES-SERIES, 660, 339-341. doi:10.1111/j.1749-6632.1992.tb21107.x

    DOI: 10.1111/j.1749-6632.1992.tb21107.x

    Antisense oligonucleotides as antiviral agents. (Conference Paper)

    Coulson, J., & Malcolm, A. D. (1992). Antisense oligonucleotides as antiviral agents.. In Biochemical Society transactions Vol. 20 (pp. 213S). doi:10.1042/bst020213s

    DOI: 10.1042/bst020213s

    1991

    The design of antisense oligonucleotides as antiviral agents (Conference Paper)

    Coulson, J., & Malcolm, A. D. B. (1991). The design of antisense oligonucleotides as antiviral agents. In Journal of Pharmacy and Pharmacology, Supplement Vol. 43 (pp. 20).