2024
Pharmacokinetics of drugs used to treat drug sensitive-tuberculosis in breastfeeding mother-infant pairs: An observational pharmacokinetic study (Journal article)
Nakijoba, R., Nakayiwa Kawuma, A., Ojara, F. W., Tabwenda, J. C., Kyeyune, J., Turyamureba, C., . . . Waitt, C. (n.d.). Pharmacokinetics of drugs used to treat drug sensitive-tuberculosis in breastfeeding mother-infant pairs: An observational pharmacokinetic study. Wellcome Open Research, 8, 216. doi:10.12688/wellcomeopenres.19113.2DOI: 10.12688/wellcomeopenres.19113.2
Physiologically-based pharmacokinetic modelling of long-acting injectable cabotegravir and rilpivirine in pregnancy. (Journal article)
Atoyebi, S., Bunglawala, F., Cottura, N., Grañana-Castillo, S., Montanha, M. C., Olagunju, A., . . . Waitt, C. (2024). Physiologically-based pharmacokinetic modelling of long-acting injectable cabotegravir and rilpivirine in pregnancy.. British journal of clinical pharmacology. doi:10.1111/bcp.16006DOI: 10.1111/bcp.16006
van der Wekken-Pas, L., Nassiwa, S., Malaba, T., Lamorde, M., Myer, L., Waitt, C., . . . Colbers, A. (2024). Comparison of dolutegravir- and efavirenz on depression, anxiety and sleep disorders in pregnant and postpartum women living with HIV; a DolPHIN2 substudy.. AIDS (London, England). doi:10.1097/qad.0000000000003852DOI: 10.1097/qad.0000000000003852
Public Attitudes Towards Access to Health Data for Research Purposes Through Citizens' Jury in Uganda. (Journal article)
Walker, L. E., Nakyeyune, L., Ashaba, A., Ahebwa, S., Nakijoba, R., Asiimwe, S. P., . . . Waitt, C. (2024). Public Attitudes Towards Access to Health Data for Research Purposes Through Citizens' Jury in Uganda.. Studies in health technology and informatics, 310, 129-133. doi:10.3233/shti230941DOI: 10.3233/shti230941
2023
Research Participants' Preferences for Individual Results of Pharmacogenomics Research: A Case of a Ugandan HIV Research Institute (Journal article)
Nabukenya, S., Waitt, C., Senyonga, R., Castelnuovo, B., Munabi, I. G., Kyaddondo, D., & Mwaka, E. S. (2023). Research Participants' Preferences for Individual Results of Pharmacogenomics Research: A Case of a Ugandan HIV Research Institute. JOURNAL OF EMPIRICAL RESEARCH ON HUMAN RESEARCH ETHICS, 18(4), 218-232. doi:10.1177/15562646231187434DOI: 10.1177/15562646231187434
Nakijoba, R., Nakayiwa Kawuma, A., Ojara, F. W., Tabwenda, J. C., Kyeyune, J., Turyahabwe, C., . . . Waitt, C. (2023). -Pharmacokinetics of antimalarial drugs used to treat uncomplicated malaria in breastfeeding mother-infant pairs: An observational pharmacokinetic study.. Wellcome open research, 8, 12. doi:10.12688/wellcomeopenres.18512.1DOI: 10.12688/wellcomeopenres.18512.1
Nakijoba, R., Nakayiwa Kawuma, A., Ojara, F. W., Tabwenda, J., Kyeyune, J., Turyahabwe, C., . . . Waitt, C. (2023). Pharmacokinetics of antimalarial drugs used to treat uncomplicated malaria in breastfeeding mother-infant pairs: An observational pharmacokinetic study. Wellcome Open Research. doi:10.12688/wellcomeopenres.18512.2DOI: 10.12688/wellcomeopenres.18512.2
Ojara, F. W., Kawuma, A. N. N., & Waitt, C. (2023). A systematic review on maternal-to-infant transfer of drugs through breast milk during the treatment of malaria, tuberculosis, and neglected tropical diseases. PLoS Neglected Tropical Diseases, 17(7). doi:10.1371/journal.pntd.0011449DOI: 10.1371/journal.pntd.0011449
Najjemba, L., Kawuma, A. N., Ojara, F. W., Obura, B., Sekaggya-Wiltshire, C., Arinaitwe, W., . . . Waitt, C. (2023). A commentary on establishing a local centre of excellence for research and training in pharmacometrics: Lessons from the pharmacometrics Africa-Uganda chapter. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY. doi:10.1111/bcp.15832DOI: 10.1111/bcp.15832
Nakijoba, R., Nakayiwa Kawuma, A., Ojara, F. W., Tabwenda, J., Kyeyune, J., Turyamureba, C., . . . Waitt, C. (2023). Pharmacokinetics of drugs used to treat drug sensitive-tuberculosis in breastfeeding mother-infant pairs: An observational pharmacokinetic study. Wellcome Open Research. doi:10.12688/wellcomeopenres.19113.1DOI: 10.12688/wellcomeopenres.19113.1
Maugans, C., Loveday, M., Hlangu, S., Waitt, C., Van Schalkwyk, M., van de Water, B., . . . Furin, J. (2023). Best practices for the care of pregnant people living with TB. INTERNATIONAL JOURNAL OF TUBERCULOSIS AND LUNG DISEASE, 27(5), 357-366. doi:10.5588/ijtld.23.0031DOI: 10.5588/ijtld.23.0031
BUZIBYE, A. L. L. A. N., Wools-Kaloustian, K., Olagunju, A., Twinomuhwezi, E., Yiannoutsos, C., Owen, A., . . . Kiragga, A. (2023). Relating CYP2B6 Genotype and EFV Resistance Among Women Living With HIV With High Viremia in Uganda: A Nested Cross-Sectional Study.. AIDS Research and Therapy. doi:10.1186/s12981-023-00514-2DOI: 10.1186/s12981-023-00514-2
Buzibye, A., Wools-Kaloustian, K., Olagunju, A., Twinomuhwezi, E., Yiannoutsos, C., Owen, A., . . . Kiragga, A. (2023). Relating CYP2B6 genotype and efavirenz resistance among post-partum women living with HIV with high viremia in Uganda: a nested cross-sectional study.. AIDS research and therapy, 20(1), 20. doi:10.1186/s12981-023-00514-2DOI: 10.1186/s12981-023-00514-2
A commentary on establishing a local centre of excellence for research and training in Pharmacometrics: Lessons from the Pharmacometrics Africa -Uganda Chapter. (Preprint)
DOI: 10.22541/au.167816419.93514129/v1
Jorgensen, A. L., Orrell, C., Waitt, C., Toh, C. -H., Sekaggya-Wiltshire, C., Hughes, D. A., . . . Pirmohamed, M. (2023). A "Bundle of Care" to Improve Anticoagulation Control in Patients Receiving Warfarin in Uganda and South Africa: Protocol for an Implementation Study. JMIR RESEARCH PROTOCOLS, 12. doi:10.2196/46710DOI: 10.2196/46710
A “Bundle of Care” to Improve Anticoagulation Control in Patients Receiving Warfarin in Uganda and South Africa: Protocol for an Implementation Study (Preprint) (Preprint)
DOI: 10.2196/preprints.46710
Communication is crucial: Lessons from COVID-19 vaccination and pregnancy (Journal article)
Cole, C., Tsakiroglou, M., & Waitt, C. (2023). Communication is crucial: Lessons from COVID-19 vaccination and pregnancy. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 89(2), 582-593. doi:10.1111/bcp.15578DOI: 10.1111/bcp.15578
Kiguba, R., Olsson, S., & Waitt, C. (2023). Pharmacovigilance in low- and middle-income countries: A review with particular focus on Africa. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 89(2), 491-509. doi:10.1111/bcp.15193DOI: 10.1111/bcp.15193
Nakijoba, R., Nakayiwa Kawuma, A., Ojara, F. W., Tabwenda, J., Kyeyune, J., Turyahabwe, C., . . . Waitt, C. (2023). Pharmacokinetics of drugs used to treat uncomplicated malaria in breastfeeding mother-infant pairs: An observational pharmacokinetic study. Wellcome Open Research. doi:10.12688/wellcomeopenres.18512.1DOI: 10.12688/wellcomeopenres.18512.1
Nalugga, E. A., Kukundakwe, M., Tibakanya, R., Tindyebwa, E., Baluku, W., Mulindwa, K., . . . Waitt, C. (2023). It Takes A Village; Involvement of Village Health Teams to Develop Tools and Resources to Communicate about Antiretroviral Use in Pregnancy and Breastfeeding at Community Level in Uganda.. Wellcome open research, 8, 510. doi:10.12688/wellcomeopenres.19088.1DOI: 10.12688/wellcomeopenres.19088.1
2022
Zuma, P., Joubert, A., van der Merwe, M., Norman, J., Waitt, C., Court, R., . . . Wiesner, L. (2022). Validation and application of a quantitative LC-MS/MS assay for the analysis of first-line anti-tuberculosis drugs, rifabutin and their metabolites in human breast milk. Journal of Chromatography B, 1211, 123489. doi:10.1016/j.jchromb.2022.123489DOI: 10.1016/j.jchromb.2022.123489
Predicting Drug-Drug Interactions between Rifampicin and Ritonavir-Boosted Atazanavir Using PBPK Modelling (vol 61, pg 375, 2022) (Journal article)
Montanha, M. C., Fabrega, F., Howarth, A., Cottura, N., Kinvig, H., Bunglawala, F., . . . Siccardi, M. (2022). Predicting Drug-Drug Interactions between Rifampicin and Ritonavir-Boosted Atazanavir Using PBPK Modelling (vol 61, pg 375, 2022). CLINICAL PHARMACOKINETICS, 61(11), 1641. doi:10.1007/s40262-022-01178-3DOI: 10.1007/s40262-022-01178-3
Asiimwe, I. G., Blockman, M., Cohen, K., Cupido, C., Hutchinson, C., Jacobson, B., . . . Pirmohamed, M. (2022). A genome-wide association study of plasma concentrations of warfarin enantiomers and metabolites in sub-Saharan black-African patients.. Frontiers in pharmacology, 13, 967082. doi:10.3389/fphar.2022.967082DOI: 10.3389/fphar.2022.967082
Malaba, T. R., Nakatudde, I., Kintu, K., Colbers, A., Chen, T., Reynolds, H., . . . Khoo, S. (2022). 72 weeks post-partum follow-up of dolutegravir versus efavirenz initiated in late pregnancy (DolPHIN-2): an open-label, randomised controlled study. LANCET HIV, 9(8), E534-E543. doi:10.1016/S2352-3018(22)00173-4DOI: 10.1016/S2352-3018(22)00173-4
Court, R., Gausi, K., Mkhize, B., Wiesner, L., Waitt, C., McIlleron, H., . . . Loveday, M. (2022). Bedaquiline exposure in pregnancy and breastfeeding in women with rifampicin-resistant tuberculosis. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 88(8), 3548-3558. doi:10.1111/bcp.15380DOI: 10.1111/bcp.15380
Alhassan, Y., Twimukye, A., Malaba, T., Myer, L., Waitt, C., Lamorde, M., . . . Taegtmeyer, M. (2022). 'I fear my partner will abandon me': the intersection of late initiation of antenatal care in pregnancy and poor ART adherence among women living with HIV in South Africa and Uganda. BMC PREGNANCY AND CHILDBIRTH, 22(1). doi:10.1186/s12884-022-04896-5DOI: 10.1186/s12884-022-04896-5
Alhassan, Y., Twimukye, A., Malaba, T., Myer, L., Waitt, C., Lamorde, M., . . . Taegtmeyer, M. (2022). <i>"It's only fatness, it doesn't kill"</i>: a qualitative study on perceptions of weight gain from use of dolutegravir-based regimens in women living with HIV in Uganda. BMC WOMENS HEALTH, 22(1). doi:10.1186/s12905-022-01814-xDOI: 10.1186/s12905-022-01814-x
Ochanda, P. N., Lamorde, M., Kintu, K., Wang, D., Chen, T., Malaba, T., . . . Khoo, S. (2022). A randomized comparison of health-related quality of life outcomes of dolutegravir versus efavirenz-based antiretroviral treatment initiated in the third trimester of pregnancy. AIDS RESEARCH AND THERAPY, 19(1). doi:10.1186/s12981-022-00446-3DOI: 10.1186/s12981-022-00446-3
High willingness to use injectable antiretroviral therapy among women who have been lost to follow-up from HIV programmes: A nested cross-sectional study (Journal article)
Odongpiny, E. L. A., Cresswell, F., Arinaitwe, A., Nakate, V., Kyenkya, J., Lamorde, M., . . . Kiragga, A. (2022). High willingness to use injectable antiretroviral therapy among women who have been lost to follow-up from HIV programmes: A nested cross-sectional study. HIV MEDICINE, 23(4), 319-323. doi:10.1111/hiv.13260DOI: 10.1111/hiv.13260
Ngandu, N. K., Lombard, C. J., Mbira, T. E., Puren, A., Waitt, C., Prendergast, A. J., . . . Goga, A. E. (2022). HIV viral load non-suppression and associated factors among pregnant and postpartum women in rural northeastern South Africa: a cross-sectional survey.. BMJ open, 12(3), e058347. doi:10.1136/bmjopen-2021-058347DOI: 10.1136/bmjopen-2021-058347
PBPK MODELING OF LONG-ACTING INJECTABLE CABOTEGRAVIR IN PREGNANCY (Conference Paper)
Atoyebi, S., Bunglawala, F., Cottura, N., Camotti-Montanha, M., Siccardi, M., & Waitt, C. (2022). PBPK MODELING OF LONG-ACTING INJECTABLE CABOTEGRAVIR IN PREGNANCY. In Fazila Bunglawala. Conference on Retroviruses and Opportunistic Infections.
Weld, E. D., Waitt, C., Barnes, K., & Garcia Bournissen, F. (2022). Twice neglected? Neglected diseases in neglected populations. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 88(2), 367-373. doi:10.1111/bcp.15148DOI: 10.1111/bcp.15148
Waitt, C., Astill, D., Zavala, E., Karron, R. A., Faden, R. R., Stratton, P., . . . Clayton, J. A. (2022). Clinical trials and pregnancy.. Communications medicine, 2, 132. doi:10.1038/s43856-022-00198-1DOI: 10.1038/s43856-022-00198-1
Physiologically based pharmacokinetic modelling of long-acting rilpivirine in pregnancy (Conference Paper)
Atoyebi, S., Granana-Castillo, S., Siccardi, M., & Waitt, C. (2022). Physiologically based pharmacokinetic modelling of long-acting rilpivirine in pregnancy. In JOURNAL OF THE INTERNATIONAL AIDS SOCIETY Vol. 25 (pp. 186-187). Retrieved from https://www.webofscience.com/
Asiimwe, I. G., Blockman, M., Cohen, K., Cupido, C., Hutchinson, C., Jacobson, B., . . . Pirmohamed, M. (2022). Stable warfarin dose prediction in sub-Saharan African patients: A machine-learning approach and external validation of a clinical dose-initiation algorithm. CPT-PHARMACOMETRICS & SYSTEMS PHARMACOLOGY, 11(1), 20-29. doi:10.1002/psp4.12740DOI: 10.1002/psp4.12740
Weld, E. D., Bailey, T. C., & Waitt, C. (2022). Ethical issues in therapeutic use and research in pregnant and breastfeeding women. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 88(1), 7-21. doi:10.1111/bcp.14914DOI: 10.1111/bcp.14914
2021
Walimbwa, S. I., Kaboggoza, J. P., Waitt, C., Byakika-Kibwika, P., D’Avolio, A., & Lamorde, M. (2021). An open-label, randomized, single intravenous dosing study to investigate the effect of fixed-dose combinations of tenofovir/lamivudine or atazanavir/ritonavir on the pharmacokinetics of remdesivir in Ugandan healthy volunteers (RemTLAR). Trials, 22(1). doi:10.1186/s13063-021-05752-1DOI: 10.1186/s13063-021-05752-1
Asiimwe, I. G., Waitt, C., Sekaggya-Wiltshire, C., Hutchinson, C., Okello, E., Zhang, E. J., . . . Pirmohamed, M. (2021). Developing and Validating a Clinical Warfarin Dose-Initiation Model for Black-African Patients in South Africa and Uganda (vol 109, pg 1564, 2021). CLINICAL PHARMACOLOGY & THERAPEUTICS, 110(5), 1402. doi:10.1002/cpt.2395DOI: 10.1002/cpt.2395
Montanha, M. C., Fabrega, F., Howarth, A., Cottura, N., Kinvig, H., Bunglawala, F., . . . Siccardi, M. (2021). Predicting Drug-Drug Interactions between Rifampicin and Ritonavir-Boosted Atazanavir Using PBPK Modelling. CLINICAL PHARMACOKINETICS. doi:10.1007/s40262-021-01067-1DOI: 10.1007/s40262-021-01067-1
Dickinson, L., Walimbwa, S., Singh, Y., Kaboggoza, J., Kintu, K., Sihlangu, M., . . . Orrell, C. (2021). Infant Exposure to Dolutegravir Through Placental and Breast Milk Transfer: A Population Pharmacokinetic Analysis of DolPHIN-1. CLINICAL INFECTIOUS DISEASES, 73(5), E1200-E1207. doi:10.1093/cid/ciaa1861DOI: 10.1093/cid/ciaa1861
Mouton, J. P., Blockman, M., Sekaggya-Wiltshire, C., Semakula, J., Waitt, C., Pirmohamed, M., & Cohen, K. (2021). Improving anticoagulation in sub-Saharan Africa: What are the challenges and how can we overcome them?. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 87(8), 3056-3068. doi:10.1111/bcp.14768DOI: 10.1111/bcp.14768
Eke, A. C., Olagunju, A., Momper, J., Penazzato, M., Abrams, E. J., Best, B. M., . . . Colbers, A. (2021). Optimizing Pharmacology Studies in Pregnant and Lactating Women Using Lessons From HIV: A Consensus Statement. CLINICAL PHARMACOLOGY & THERAPEUTICS, 110(1), 36-48. doi:10.1002/cpt.2048DOI: 10.1002/cpt.2048
Asiimwe, I. G., Waitt, C., Sekaggya-Wiltshire, C., Hutchinson, C., Okello, E., Zhang, E. J., . . . Pirmohamed, M. (2021). Developing and Validating a Clinical Warfarin Dose-Initiation Model for Black-African Patients in South Africa and Uganda. CLINICAL PHARMACOLOGY & THERAPEUTICS, 109(6), 1564-1574. doi:10.1002/cpt.2128DOI: 10.1002/cpt.2128
Hazenberg, P., Navaratnam, K., Busuulwa, P., & Waitt, C. (2021). Anti-Infective Dosing in Special Populations: Pregnancy. CLINICAL PHARMACOLOGY & THERAPEUTICS, 109(4), 977-986. doi:10.1002/cpt.2192DOI: 10.1002/cpt.2192
Semakula, J., Kisa, G., Mouton, J., Cohen, K., Blockman, M., Pirmohamed, M., . . . Waitt, C. (2021). Anticoagulation in sub-Saharan Africa: Are Direct Oral Anticoagulants the answer? A review of lessons learnt from warfarin. British Journal of Clinical Pharmacology. doi:10.1111/bcp.14796DOI: 10.1111/bcp.14796
Advancing knowledge in perinatal HIV treatment. (Journal article)
Waitt, C., Myer, L., & Khoo, S. (2021). Advancing knowledge in perinatal HIV treatment.. The lancet. HIV, 8(3), e124-e125. doi:10.1016/s2352-3018(20)30306-4DOI: 10.1016/s2352-3018(20)30306-4
2020
De Nicolo, A., Ianniello, A., Ferrara, M., Avataneo, V., Cusato, J., Antonucci, M., . . . D'Avolio, A. (2021). Validation of a UHPLC-MS/MS Method to Quantify Twelve Antiretroviral Drugs within Peripheral Blood Mononuclear Cells from People Living with HIV. PHARMACEUTICALS, 14(1). doi:10.3390/ph14010012DOI: 10.3390/ph14010012
Alhassan, Y., Twimukye, A., Malaba, T., Orrell, C., Myer, L., Waitt, C., . . . Taegtmeyer, M. (2020). Community acceptability of dolutegravir-based HIV treatment in women: a qualitative study in South Africa and Uganda. BMC Public Health, 20(1). doi:10.1186/s12889-020-09991-wDOI: 10.1186/s12889-020-09991-w
Onsite Mentorship Model for Isolation and Management of Viral Hemorrhagic Fever Syndromes at a Ugandan Hospital (Conference Paper)
Waitt, P., Nakato, S., Ayebare, R., Ssekabira, U., Nanyondo, J., Waitt, C., . . . Lamorde, M. (2020). Onsite Mentorship Model for Isolation and Management of Viral Hemorrhagic Fever Syndromes at a Ugandan Hospital. In INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY Vol. 41 (pp. S491-S492). doi:10.1017/ice.2020.1167DOI: 10.1017/ice.2020.1167
Alhassan, Y., Twimukye, A., Malaba, T., Orrell, C., Myer, L., Waitt, C., . . . Taegtmeyer, M. (2020). Engendering health systems in response to national rollout of dolutegravir-based regimens among women of childbearing potential: a qualitative study with stakeholders in South Africa and Uganda. BMC HEALTH SERVICES RESEARCH, 20(1). doi:10.1186/s12913-020-05580-0DOI: 10.1186/s12913-020-05580-0
Avataneo, V., de Nicolò, A., Cusato, J., Antonucci, M., Manca, A., Palermiti, A., . . . D’Avolio, A. (2020). Development and validation of a UHPLC-MS/MS method for quantification of the prodrug remdesivir and its metabolite GS-441524: a tool for clinical pharmacokinetics of SARS-CoV-2/COVID-19 and Ebola virus disease. Journal of Antimicrobial Chemotherapy. doi:10.1093/jac/dkaa152DOI: 10.1093/jac/dkaa152
Perez Nicholas, O., Lamorde, M., Kintu, K., Wang, D., Chen, T., Malaba, T., . . . Khoo, S. (2020). COMPARATIVE QUALITY OF LIFE OUTCOMES OF DOLUTEGRAVIR-BASED OR EFAVIRENZ-BASED ANTIRETOVIRAL TREATMENT IN PREGNANCY FOR LATE PRESENTORS BETWEEN THE 3RD TRIAL-MESTER AND 48 WEEKS POSTPARTUM. In VALUE IN HEALTH Vol. 23 (pp. S184). Retrieved from https://www.webofscience.com/
Kintu, K., Malaba, T., Nakibuka, J., Papamichael, C., Colbers, A., Byrne, K., . . . Khoo, S. (2020). Dolutegravir versus efavirenz when starting HIV therapy in late pregnancy: a randomised controlled trial. The Lancet HIV, 7(5), e332-e339. doi:10.1016/s2352-3018(20)30050-3DOI: 10.1016/s2352-3018(20)30050-3
Semakula, J. R., Mouton, J. P., Jorgensen, A., Hutchinson, C., Allie, S., Semakula, L., . . . Cohen, K. (2020). A cross-sectional evaluation of five warfarin anticoagulation services in Uganda and South Africa. PLOS ONE, 15(1). doi:10.1371/journal.pone.0227458DOI: 10.1371/journal.pone.0227458
2019
Feiterna-Sperling, C., Krüger, R., Amara, A., Khoo, S., & Waitt, C. (2019). Pharmacokinetics of maraviroc in plasma and breastmilk in a treatment-experienced perinatally HIV-1-infected woman.. AIDS (London, England), 33(15), 2443-2444. doi:10.1097/qad.0000000000002360DOI: 10.1097/qad.0000000000002360
Fairlie, L., Waitt, C., Lockman, S., Moorehouse, M., Abrams, E., Clayden, P., . . . Cherisch, M. (2019). Inclusion of pregnant women in antiretroviral drug research: what is needed to move forwards?. Journal of the International AIDS Society. doi:10.1002/jia2.25372DOI: 10.1002/jia2.25372
Feiterna-Sperling, C., Krueger, R., Amara, A., Khoo, S., & Waitt, C. (2019). Pharmacokinetics of maraviroc in plasma and breastmilk in a treatment-experienced perinatally HIV-1-infected woman. AIDS, 33(15), 2443-2444. doi:10.1097/QAD.0000000000002360DOI: 10.1097/QAD.0000000000002360
Walimbwa, S., Lamorde, M., Waitt, C., Amara, A., & Khoo, S. (2019). Reply to Banda et al., "Interpretation of Drug Interactions between Dolutegravir and Artemether-Lumefantrine or Artesunate-Amodiaquine". ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 63(6). doi:10.1128/AAC.00593-19DOI: 10.1128/AAC.00593-19
Prendergast, A. J., Goga, A. E., Waitt, C., Gessain, A., Taylor, G. P., Rollins, N., . . . Van de Perre, P. (2019). Transmission of CMV, HTLV-1, and HIV through breastmilk. LANCET CHILD & ADOLESCENT HEALTH, 3(4), 264-273. doi:10.1016/S2352-4642(19)30024-0DOI: 10.1016/S2352-4642(19)30024-0
Pharmacokinetics, Placental and Breastmilk Transfer of Antiretroviral Drugs in Pregnant and Lactating Women Living with HIV. (Journal article)
Hodel, E. M., Marzolini, C., Waitt, C., & Rakhmanina, N. (2019). Pharmacokinetics, Placental and Breastmilk Transfer of Antiretroviral Drugs in Pregnant and Lactating Women Living with HIV.. Current Pharmaceutical Design. doi:10.2174/1381612825666190320162507DOI: 10.2174/1381612825666190320162507
Gini, J., Olagunju, A., Dickinson, L., Waitt, C., Neary, M., Else, L. J., . . . Khoo, S. (2019). Impact of pharmacogenetics and pregnancy on tenofovir and emtricitabine pharmacokinetics. PHARMACOGENOMICS, 20(4), 217-224. doi:10.2217/pgs-2018-0111DOI: 10.2217/pgs-2018-0111
Walimbwa, S. I., Lamorde, M., Waitt, C., Kaboggoza, J., Else, L., Byakika-Kibwika, P., . . . Khoo, S. H. (2019). Drug Interactions between Dolutegravir and Artemether-Lumefantrine or Artesunate-Amodiaquine. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 63(2). doi:10.1128/AAC.01310-18DOI: 10.1128/aac.01310-18
Waitt, C., Orrell, C., Walimbwa, S., Singh, Y., Kintu, K., Simmons, B., . . . Khoo, S. (2019). Safety and pharmacokinetics of dolutegravir in pregnant mothers with HIV infection and their neonates: A randomised trial (DolPHIN-1 study). PLOS MEDICINE, 16(9). doi:10.1371/journal.pmed.1002895DOI: 10.1371/journal.pmed.1002895
2018
Validation and clinical application of a novel LC-MS method for quantification of dolutegravir in breast milk (Journal article)
Gini, J., Penchala, S. D., Amara, A., Challenger, E., Egan, D., Waitt, C., . . . Else, L. J. (2018). Validation and clinical application of a novel LC-MS method for quantification of dolutegravir in breast milk. BIOANALYSIS, 10(23), 1933-1945. doi:10.4155/bio-2018-0085DOI: 10.4155/bio-2018-0085
Seden, K., Kiiza, D., Laker, E., Arinaitwe, W. J., Waitt, C., Lamorde, M., & Khoo, S. (2018). High prevalence and long duration of nervous system and psychiatric adverse drug reactions in Ugandan patients taking efavirenz 600 mg daily. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 73(11), 3158-3161. doi:10.1093/jac/dky298DOI: 10.1093/jac/dky298
Waitt, C. J., Lowe, N., van de Perre, P., Lyon, F., Loutfy, M., & Aebi-Popp, K. (2018). Does U=U for breastfeeding mothers and infants? Breastfeeding by mothers on effective treatment for HIV infection in high-income settings. The Lancet HIV, 5(9), E531-E536. doi:10.1016/S2352-3018(18)30098-5DOI: 10.1016/S2352-3018(18)30098-5
Orrell, C., Kintu, K., Coombs, J. A., Amara, A., Myer, L., Kaboggoza, J., . . . Lamorde, M. (2018). DolPHIN-1: Randomised controlled trial of dolutegravir (DTG)- versus efavirenz (EFV)-based therapy in mothers initiating antiretroviral treatment in late pregnancy. In JOURNAL OF THE INTERNATIONAL AIDS SOCIETY Vol. 21 (pp. 166). Retrieved from https://www.webofscience.com/
Drug Interactions Between Dolutegravir and Artemether-Lumefantrine or Artesunate-Amodiaquine (Journal article)
Walimbwa, S., Lamorde, M., Waitt, C., Kaboggoza, J., Else, L., Byakika-Kibwika, P., . . . Khoo, S. (2018). Drug Interactions Between Dolutegravir and Artemether-Lumefantrine or Artesunate-Amodiaquine. doi:10.1101/351684DOI: 10.1101/351684
Waitt, C., Olagunju, A., Nakalema, S., Kyohaire, I., Owen, A., Lamorde, M., & Khoo, S. (2018). Plasma and Breast Milk Pharmacokinetics of Emtricitabine, Tenofovir and Lamivudine Using Dried Blood and Breast Milk Spots in Nursing African Mother-Infant Pairs. Journal of Antimicrobial Chemotherapy, 73(4), 1013-1019. doi:10.1093/jac/dkx507DOI: 10.1093/jac/dkx507
2017
Waitt, C., Penchala, S. D., Olagunju, A., Amara, A., Else, L., Lamorde, M., & Khoo, S. (2017). Development, validation and clinical application of a method for the simultaneous quantification of lamivudine, emtricitabine and tenofovir in dried blood and dried breast milk spots using LC-MS/MS. Journal of Chromatography B, 1060, 300-307. doi:10.1016/j.jchromb.2017.06.012DOI: 10.1016/j.jchromb.2017.06.012
2016
Lewis, J. M., Volny-Anne, A., Waitt, C., Boffito, M., & Khoo, S. (2016). Dosing antiretroviral medication when crossing time zones: a review. AIDS, 30(2), 267-271. doi:10.1097/QAD.0000000000000920DOI: 10.1097/QAD.0000000000000920
Hawcutt, D. B., Russell, N. J., Maqsood, H., Kouranloo, K., Gomberg, S., Waitt, C., . . . Turner, M. A. (2016). Spontaneous adverse drug reaction reports for neonates and infants in the UK 2001-2010: content and utility analysis. British journal of clinical pharmacology, 82(06), 1601-1612. doi:10.1111/bcp.13067DOI: 10.1111/bcp.13067
2015
Monocyte unresponsiveness and impaired IL1β, TNFα and IL7 production are associated with a poor outcome in Malawian adults with pulmonary tuberculosis (Journal article)
Waitt, C. J., Banda, P., Glennie, S., Kampmann, B., Squire, S. B., Pirmohamed, M., & Heyderman, R. S. (2015). Monocyte unresponsiveness and impaired IL1β, TNFα and IL7 production are associated with a poor outcome in Malawian adults with pulmonary tuberculosis. BMC Infectious Diseases, 15. doi:10.1186/s12879-015-1274-4DOI: 10.1186/s12879-015-1274-4
Validation and clinical application of a method to quantify nevirapine in dried blood spots and dried breast-milk spots (Journal article)
Olagunju, A., Amara, A., Waitt, C., Else, L., Penchala, S. D., Bolaji, O., . . . Khoo, S. (2015). Validation and clinical application of a method to quantify nevirapine in dried blood spots and dried breast-milk spots. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 70(10), 2816-2822. doi:10.1093/jac/dkv174DOI: 10.1093/jac/dkv174
Breast Milk Pharmacokinetics of Efavirenz and Breastfed Infants' Exposure in Genetically Defined Subgroups of Mother-Infant Pairs: An Observational Study (Journal article)
Olagunju, A., Bolaji, O., Amara, A., Waitt, C., Else, L., Adejuyigbe, E., . . . Owen, A. (2015). Breast Milk Pharmacokinetics of Efavirenz and Breastfed Infants' Exposure in Genetically Defined Subgroups of Mother-Infant Pairs: An Observational Study. Clin Infect Dis, 61(3), 453-463. doi:10.1093/cid/civ317DOI: 10.1093/cid/civ317
Is infant exposure to antiretroviral drugs during breastfeeding quantitatively important? A systematic review and meta-analysis of pharmacokinetic studies (Journal article)
Waitt, C. J., Garner, P., Bonnett, L. J., Khoo, S. H., & Else, L. J. (2015). Is infant exposure to antiretroviral drugs during breastfeeding quantitatively important? A systematic review and meta-analysis of pharmacokinetic studies. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 70(7), 1928-1941. doi:10.1093/jac/dkv080DOI: 10.1093/jac/dkv080
Olagunju, A., Bolaji, O. O., Amara, A., Waitt, C., Else, L., Soyinka, J., . . . Khoo, S. (2015). Development, validation and clinical application of a novel method for the quantification of efavirenz in dried breast milk spots using LC-MS/MS. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 70(2), 555-561. doi:10.1093/jac/dku420DOI: 10.1093/jac/dku420
2014
Waitt, P. I., Mukaka, M., Goodson, P., SimuKonda, F. D., Waitt, C. J., Feasey, N., . . . Heyderman, R. S. (2014). Sepsis carries a high mortality among hospitalised adults in Malawi in the era of antiretroviral therapy scale-up: A longitudinal cohort study. Journal of Infection, 70(1), 11-19. doi:10.1016/j.jinf.2014.07.004DOI: 10.1016/j.jinf.2014.07.004
2013
Birkhamshaw, E., Waitt, C. J., Innes, M., & Waitt, P. I. (2013). Severity Assessment of Lower Respiratory Tract Infection in Malawi: Derivation of a Novel Index (SWAT-Bp) Which Outperforms CRB-65. PLOS ONE, 8(12). doi:10.1371/journal.pone.0082178DOI: 10.1371/journal.pone.0082178
The effect of a tuberculosis chest X-ray image reference set on non-expert reader performance (Journal article)
Waitt, C. J., Joekes, E. C., Jesudason, N., Waitt, P. I., Goodson, P., Likumbo, G., . . . Squire, S. B. (2013). The effect of a tuberculosis chest X-ray image reference set on non-expert reader performance. EUROPEAN RADIOLOGY, 23(9), 2459-2468. doi:10.1007/s00330-013-2840-zDOI: 10.1007/s00330-013-2840-z
2011
Early Deaths During Tuberculosis Treatment Are Associated With Depressed Innate Responses, Bacterial Infection, and Tuberculosis Progression (Journal article)
Waitt, C. J., Banda, N. P. K., White, S. A., Kampmann, B., Kumwenda, J., Heyderman, R. S., . . . Squire, S. B. (2011). Early Deaths During Tuberculosis Treatment Are Associated With Depressed Innate Responses, Bacterial Infection, and Tuberculosis Progression. JOURNAL OF INFECTIOUS DISEASES, 204(3), 358-362. doi:10.1093/infdis/jir265DOI: 10.1093/infdis/jir265
A systematic review of risk factors for death in adults during and after tuberculosis treatment (Journal article)
Waitt, C. J., & Squire, S. B. (2011). A systematic review of risk factors for death in adults during and after tuberculosis treatment. INTERNATIONAL JOURNAL OF TUBERCULOSIS AND LUNG DISEASE, 15(7), 871-885. doi:10.5588/ijtld.10.0352DOI: 10.5588/ijtld.10.0352
Waitt, C. (2011). Investigation into Early Mortality in Malawian Adults treated for Pulmonary Tuberculosis. (PhD Thesis, The University of Liverpool).
2008
Effect of atazanavir and ritonavir on the differentiation and adipokine secretion of human subcutaneous and omental preadipocytes (Journal article)
Jones, S. P., Waitt, C., Sutton, R., Back, D. J., & Pirmohamed, M. (2008). Effect of atazanavir and ritonavir on the differentiation and adipokine secretion of human subcutaneous and omental preadipocytes. AIDS, 22(11), 1293-1298. doi:10.1097/qad.0b013e3283021a4fDOI: 10.1097/qad.0b013e3283021a4f
Effect of atazanavir and ritonavir on the differentiation and adipokine secretion of human subcutaneous and omental preadipocytes (Journal article)
Jones, S. P., Waitt, C., Sutton, R., Back, D. J., & Pirmohamed, M. (2008). Effect of atazanavir and ritonavir on the differentiation and adipokine secretion of human subcutaneous and omental preadipocytes. AIDS, 22(11), 1293-1298. doi:10.1097/QAD.0b013e3283021a4fDOI: 10.1097/QAD.0b013e3283021a4f
2007
A rapid and sensitive HPLC-MS method for the detection of plasma and cellular rifampicin (Journal article)
Hartkoorn, R. C., Khoo, S., Back, D. J., Tjia, J. F., Waitt, C. J., Chaponda, M., . . . Ward, S. A. (2007). A rapid and sensitive HPLC-MS method for the detection of plasma and cellular rifampicin. JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 857(1), 76-82. doi:10.1016/j.jchromb.2007.07.005DOI: 10.1016/j.jchromb.2007.07.005
2005
A retained intravascular medical device and <i>Streptococcus bovis</i> infection, providing early diagnosis of an occult malignancy (Journal article)
Beadsworth, M., Waitt, C., Jenkins, N., Amadi, A., Nye, F., & Beeching, N. (2005). A retained intravascular medical device and <i>Streptococcus bovis</i> infection, providing early diagnosis of an occult malignancy. JOURNAL OF INFECTION, 50(2), 165-167. doi:10.1016/j.jinf.2004.08.024DOI: 10.1016/j.jinf.2004.08.024
2004
Intravenous therapy. (Journal article)
Waitt, C., Waitt, P., & Pirmohamed, M. (2004). Intravenous therapy.. Postgraduate medical journal, 80(939), 1-6. doi:10.1136/pmj.2003.010421DOI: 10.1136/pmj.2003.010421
Intravenous therapy (Journal article)
Waitt, C., Waitt, P., & Pirmohamed, M. (2004). Intravenous therapy. POSTGRADUATE MEDICAL JOURNAL, 80(939), 1-6. doi:10.1136/pmj.2003.010421DOI: 10.1136/pmj.2003.010421