Publications
2024
Attaining Equity of Access to Research: Perspective on Research in Pregnancy and Breastfeeding Following Dolores Shockley Lecture at ASCPT2024.
Waitt, C., Asiimwe, S. P., Ojara, F. W., Nakijoba, R., Kawuma, A. N., & Castelnuovo, B. (2024). Attaining Equity of Access to Research: Perspective on Research in Pregnancy and Breastfeeding Following Dolores Shockley Lecture at ASCPT2024.. Clinical pharmacology and therapeutics. doi:10.1002/cpt.3344
Denying access to long-acting injectable treatment for HIV: an open letter.
Malaba, T., Henn, J., Waitt, C., Myer, L., Khoo, S., Taegtmeyer, M., . . . DolPHIN3 consortium. (2024). Denying access to long-acting injectable treatment for HIV: an open letter.. The lancet. HIV, 11(12), e802. doi:10.1016/s2352-3018(24)00305-9
Maternal mortality following caesarean section in a low-resource setting: a National Malawian Surveillance Study.
Riches, J., Chimwaza, Y., Magreta Chakhame, B. I., Milln, J., Twabi, H. H., Bilesi, R., . . . Lissauer, D. (2024). Maternal mortality following caesarean section in a low-resource setting: a National Malawian Surveillance Study.. BMJ global health, 9(11), e016999. doi:10.1136/bmjgh-2024-01699
What can pharmacokinetic modelling do for you? Rational design and interpretation of clinical studies.
Ojara, F. W., Kawuma, A. N., & Waitt, C. (2024). What can pharmacokinetic modelling do for you? Rational design and interpretation of clinical studies.. British journal of clinical pharmacology. doi:10.1111/bcp.16341
Striving for balance in decisions on antenatal pharmacotherapy
Koldeweij, C., Jans, V. A. A. M., Waitt, C., Greupink, R., Auweele, K. L. H. E. V., Franklin, B. D., . . . de Wildt, S. N. (2024). Striving for balance in decisions on antenatal pharmacotherapy. The Lancet, 404(10464), 1779-1782. doi:10.1016/s0140-6736(24)02069-5
Cost-Effectiveness of Dolutegravir Compared With Efavirenz for Prevention of Perinatal Transmission in Women Presenting With HIV in Late Pregnancy in Uganda.
Nuwamanya, E., Nassiwa, S. C., Kuznik, A., Waitt, C., Malaba, T., Myer, L., . . . Lamorde, M. (2024). Cost-Effectiveness of Dolutegravir Compared With Efavirenz for Prevention of Perinatal Transmission in Women Presenting With HIV in Late Pregnancy in Uganda.. Value in health regional issues, 44, 101017. doi:10.1016/j.vhri.2024.101017
Evaluation of pharmacokinetics of Tenofovir Alafenamide (TAF) and Tenofovir Disoproxil (TDF) in pregnant and postpartum women in South Africa: PrEP-PP PK study.
Joseph Davey, D., Dadan, S., Bheemraj, K., Waitt, C., Khoo, S., Myer, L., . . . Orrell, C. (2024). Evaluation of pharmacokinetics of Tenofovir Alafenamide (TAF) and Tenofovir Disoproxil (TDF) in pregnant and postpartum women in South Africa: PrEP-PP PK study.. Antiviral research, 231, 106014. doi:10.1016/j.antiviral.2024.106014
Interim analysis, a tool to enhance efficiency of pharmacokinetic studies: Pharmacokinetics of rifampicin in lactating mother–infant pairs
Kawuma, A. N., Ojara, F. W., Buzibye, A., Castelnuovo, B., Tabwenda, J. C., Kyeyune, J., . . . Waitt, C. (n.d.). Interim analysis, a tool to enhance efficiency of pharmacokinetic studies: Pharmacokinetics of rifampicin in lactating mother–infant pairs. CPT: Pharmacometrics & Systems Pharmacology. doi:10.1002/psp4.13247
Physiologically based pharmacokinetic modeling of drug–drug interactions between ritonavir‐boosted atazanavir and rifampicin in pregnancy
Atoyebi, S., Montanha, M. C., Nakijoba, R., Orrell, C., Mugerwa, H., Siccardi, M., . . . Waitt, C. (n.d.). Physiologically based pharmacokinetic modeling of drug–drug interactions between ritonavir‐boosted atazanavir and rifampicin in pregnancy. CPT: Pharmacometrics & Systems Pharmacology. doi:10.1002/psp4.13268
Population pharmacokinetic modeling of paired plasma-breast milk lamivudine data for estimation of infant exposure in breastfeeding mother-infant pairs.
Ojara, F. W., Kawuma, A. N., Nakalema, S., Kyohairwe, I., Nakijoba, R., Lamorde, M., . . . Waitt, C. (2024). Population pharmacokinetic modeling of paired plasma-breast milk lamivudine data for estimation of infant exposure in breastfeeding mother-infant pairs.. CPT: pharmacometrics & systems pharmacology, 13(11), 1978-1989. doi:10.1002/psp4.13274
Using PBPK modeling to supplement clinical data and support the safe and effective use of dolutegravir in pregnant and lactating women
Ning, J., Pansari, A., Rowland Yeo, K., Heikkinen, A. T., Waitt, C., & Almond, L. M. (n.d.). Using PBPK modeling to supplement clinical data and support the safe and effective use of dolutegravir in pregnant and lactating women. CPT: Pharmacometrics & Systems Pharmacology. doi:10.1002/psp4.13251
What can pharmacokinetic modelling do for you? Rational design and interpretation of clinical studies
Recruitment of pregnant and breastfeeding women in pharmacokinetic studies: strategies, opportunities, barriers, and recommendations.
Nakijoba, R., Kawuma, A. N., Asiimwe, S. P., Turyahabwe, C., Tabwenda, J. C., Kyeyune, J., . . . Waitt, C. (2024). Recruitment of pregnant and breastfeeding women in pharmacokinetic studies: strategies, opportunities, barriers, and recommendations.. BMC research notes, 17(1), 312. doi:10.1186/s13104-024-06946-x
Cross‐disciplinary mathematical modelling to benefit healthcare – could clinical pharmacology play an enabling role?
Maluleke, T., Benecke, R., Oladejo, S., Feulner, G., Kern, S., Lister, J., . . . Pillai, G. (n.d.). Cross‐disciplinary mathematical modelling to benefit healthcare – could clinical pharmacology play an enabling role?. British Journal of Clinical Pharmacology. doi:10.1111/bcp.16192
Addressing health equity for breastfeeding women: primaquine for Plasmodium vivax radical cure.
Abla, N., Marrast, A. C., Jambert, E., Richardson, N., Duparc, S., Almond, L., . . . El Gaaloul, M. (2024). Addressing health equity for breastfeeding women: primaquine for Plasmodium vivax radical cure.. Malaria journal, 23(1), 287. doi:10.1186/s12936-024-05112-9
Clinical pharmacology considerations and drug-drug interactions with long-acting cabotegravir and rilpivirine relevant to sub-Saharan Africa.
Steulet, A., Obura, B., Waitt, C., Laker, E., Nicol, M. R., & Cresswell, F. V. (2024). Clinical pharmacology considerations and drug-drug interactions with long-acting cabotegravir and rilpivirine relevant to sub-Saharan Africa.. British journal of clinical pharmacology, 90(9), 2079-2091. doi:10.1111/bcp.16154
Meta-analysis of genome-wide association studies of stable warfarin dose in patients of African ancestry.
Asiimwe, I. G., Blockman, M., Cavallari, L. H., Cohen, K., Cupido, C. S., Dandara, C., . . . Pirmohamed, M. (2024). Meta-analysis of genome-wide association studies of stable warfarin dose in patients of African ancestry.. Blood advances, bloodadvances.2024014227. doi:10.1182/bloodadvances.2024014227
Pharmacokinetics of drugs used to treat drug sensitive-tuberculosis in breastfeeding mother-infant pairs: An observational pharmacokinetic study
Nakijoba, R., Nakayiwa Kawuma, A., Ojara, F. W., Tabwenda, J. C., Kyeyune, J., Turyamureba, C., . . . Waitt, C. (n.d.). Pharmacokinetics of drugs used to treat drug sensitive-tuberculosis in breastfeeding mother-infant pairs: An observational pharmacokinetic study. Wellcome Open Research, 8, 216. doi:10.12688/wellcomeopenres.19113.4
Clinical, pharmacological, and qualitative characterization of drug-drug interactions in pregnant women initiating HIV therapy in Sub-Saharan Africa.
Kiiza, D., Rostami-Hochaghan, D., Alhassan, Y., Seden, K., Reynolds, H., Kaboggoza, J. P., . . . Lamorde, M. (2024). Clinical, pharmacological, and qualitative characterization of drug-drug interactions in pregnant women initiating HIV therapy in Sub-Saharan Africa.. The Journal of antimicrobial chemotherapy, dkae232. doi:10.1093/jac/dkae232
Pharmacokinetics and Safety of Twice-daily Ritonavir-boosted Atazanavir With Rifampicin.
Gausi, K., Mugerwa, H., Siccardi, M., Montanha, M. C., Lamorde, M., Wiesner, L., . . . Waitt, C. (2024). Pharmacokinetics and Safety of Twice-daily Ritonavir-boosted Atazanavir With Rifampicin.. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 78(5), 1246-1255. doi:10.1093/cid/ciad700
The role of community engagement in promoting research participants' understanding of pharmacogenomic research results: Perspectives of stakeholders involved in HIV/AIDS research and treatment.
Nabukenya, S., Kyaddondo, D., Munabi, I. G., Waitt, C., Twimukye, A., & Mwaka, E. S. (2024). The role of community engagement in promoting research participants' understanding of pharmacogenomic research results: Perspectives of stakeholders involved in HIV/AIDS research and treatment.. PloS one, 19(4), e0299081. doi:10.1371/journal.pone.0299081
‘<i>It is a complex process, but it’s very important to return these results to participants’</i>. Stakeholders’ perspectives on the ethical considerations for returning individual pharmacogenomics research results to people living with HIV
Nabukenya, S., Kyaddondo, D., Twimukye, A., Munabi, I. G., Waitt, C., & Mwaka, E. S. (2024). ‘<i>It is a complex process, but it’s very important to return these results to participants’</i>. Stakeholders’ perspectives on the ethical considerations for returning individual pharmacogenomics research results to people living with HIV. Research Ethics, 20(2), 363-387. doi:10.1177/17470161231207739
Clinical Pharmacology considerations and drug-drug interactions with long-acting cabotegravir and rilpivirine relevant to a sub-Saharan Africa
Support, not blame: safe partner disclosure among women diagnosed with HIV late in pregnancy in South Africa and Uganda.
Twimukye, A., Alhassan, Y., Ringwald, B., Malaba, T., Myer, L., Waitt, C., . . . Taegtmeyer, M. (2024). Support, not blame: safe partner disclosure among women diagnosed with HIV late in pregnancy in South Africa and Uganda.. AIDS research and therapy, 21(1), 14. doi:10.1186/s12981-024-00600-z
Physiologically-based pharmacokinetic modelling of long-acting injectable cabotegravir and rilpivirine in pregnancy
Atoyebi, S., Bunglawala, F., Cottura, N., Grañana-Castillo, S., Montanha, M., Olagunju, A., . . . Waitt, C. (2024). Physiologically-based pharmacokinetic modelling of long-acting injectable cabotegravir and rilpivirine in pregnancy. British Journal of Clinical Pharmacology. doi:10.1111/bcp.16006
Comparison of dolutegravir- and efavirenz on depression, anxiety and sleep disorders in pregnant and postpartum women living with HIV; a DolPHIN2 substudy.
van der Wekken-Pas, L., Nassiwa, S., Malaba, T., Lamorde, M., Myer, L., Waitt, C., . . . Colbers, A. (2024). Comparison of dolutegravir- and efavirenz on depression, anxiety and sleep disorders in pregnant and postpartum women living with HIV; a DolPHIN2 substudy.. AIDS (London, England). doi:10.1097/qad.0000000000003852
Public Attitudes Towards Access to Health Data for Research Purposes Through Citizens' Jury in Uganda.
Walker, L. E., Nakyeyune, L., Ashaba, A., Ahebwa, S., Nakijoba, R., Asiimwe, S. P., . . . Waitt, C. (2024). Public Attitudes Towards Access to Health Data for Research Purposes Through Citizens' Jury in Uganda.. Studies in health technology and informatics, 310, 129-133. doi:10.3233/shti230941
Adapting citizens’ jury methodology for use in Uganda: use of creative arts as a tool in deliberative, participatory research
Waitt, C., Nakyeyune, L., Ashaba, A., Ahebwa, S., Nakijoba, R., Asiimwe, S. P., . . . Walker, L. E. (n.d.). Adapting citizens’ jury methodology for use in Uganda: use of creative arts as a tool in deliberative, participatory research. International Journal of Social Research Methodology, 1-10. doi:10.1080/13645579.2024.2396371
Pharmacokinetics of drugs used to treat drug sensitive-tuberculosis in breastfeeding mother-infant pairs: An observational pharmacokinetic study
Pharmacokinetics of drugs used to treat drug sensitive-tuberculosis in breastfeeding mother-infant pairs: An observational pharmacokinetic study.
Nakijoba, R., Nakayiwa Kawuma, A., Ojara, F. W., Tabwenda, J. C., Kyeyune, J., Turyamureba, C., . . . Waitt, C. (2023). Pharmacokinetics of drugs used to treat drug sensitive-tuberculosis in breastfeeding mother-infant pairs: An observational pharmacokinetic study.. Wellcome open research, 8, 216. doi:10.12688/wellcomeopenres.19113.3
2023
PA-727 Physiologically-based pharmacokinetic modelling of drug-drug interactions between ritonavir-boosted atazanavir and rifampicin in pregnancy
Atoyebi, S., Montanha, M. C., Najjemba, L., Orrell, C., Jennings, L., Mugerwa, H., . . . Waitt, C. (2023). PA-727 Physiologically-based pharmacokinetic modelling of drug-drug interactions between ritonavir-boosted atazanavir and rifampicin in pregnancy. In Abstracts of Poster and e-Poster Presentations (pp. A114.2-A114). BMJ Publishing Group Ltd. doi:10.1136/bmjgh-2023-edc.279
Research Participants' Preferences for Individual Results of Pharmacogenomics Research: A Case of a Ugandan HIV Research Institute
Nabukenya, S., Waitt, C., Senyonga, R., Castelnuovo, B., Munabi, I. G., Kyaddondo, D., & Mwaka, E. S. (2023). Research Participants' Preferences for Individual Results of Pharmacogenomics Research: A Case of a Ugandan HIV Research Institute. JOURNAL OF EMPIRICAL RESEARCH ON HUMAN RESEARCH ETHICS, 18(4), 218-232. doi:10.1177/15562646231187434
-Pharmacokinetics of antimalarial drugs used to treat uncomplicated malaria in breastfeeding mother-infant pairs: An observational pharmacokinetic study.
Nakijoba, R., Nakayiwa Kawuma, A., Ojara, F. W., Tabwenda, J. C., Kyeyune, J., Turyahabwe, C., . . . Waitt, C. (2023). -Pharmacokinetics of antimalarial drugs used to treat uncomplicated malaria in breastfeeding mother-infant pairs: An observational pharmacokinetic study.. Wellcome open research, 8, 12. doi:10.12688/wellcomeopenres.18512.1
Pharmacokinetics of antimalarial drugs used to treat uncomplicated malaria in breastfeeding mother-infant pairs: An observational pharmacokinetic study
Nakijoba, R., Nakayiwa Kawuma, A., Ojara, F. W., Tabwenda, J., Kyeyune, J., Turyahabwe, C., . . . Waitt, C. (2023). Pharmacokinetics of antimalarial drugs used to treat uncomplicated malaria in breastfeeding mother-infant pairs: An observational pharmacokinetic study. Wellcome Open Research. doi:10.12688/wellcomeopenres.18512.2
A systematic review on maternal-to-infant transfer of drugs through breast milk during the treatment of malaria, tuberculosis, and neglected tropical diseases
Ojara, F. W., Kawuma, A. N. N., & Waitt, C. (2023). A systematic review on maternal-to-infant transfer of drugs through breast milk during the treatment of malaria, tuberculosis, and neglected tropical diseases. PLoS Neglected Tropical Diseases, 17(7). doi:10.1371/journal.pntd.0011449
A commentary on establishing a local centre of excellence for research and training in pharmacometrics: Lessons from the pharmacometrics Africa-Uganda chapter
Najjemba, L., Kawuma, A. N., Ojara, F. W., Obura, B., Sekaggya-Wiltshire, C., Arinaitwe, W., . . . Waitt, C. (2023). A commentary on establishing a local centre of excellence for research and training in pharmacometrics: Lessons from the pharmacometrics Africa-Uganda chapter. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY. doi:10.1111/bcp.15832
Physiologically-based pharmacokinetic modelling of long-acting injectable cabotegravir and rilpivirine in pregnancy
Pharmacokinetics of drugs used to treat drug sensitive-tuberculosis in breastfeeding mother-infant pairs: An observational pharmacokinetic study
Nakijoba, R., Nakayiwa Kawuma, A., Ojara, F. W., Tabwenda, J., Kyeyune, J., Turyamureba, C., . . . Waitt, C. (2023). Pharmacokinetics of drugs used to treat drug sensitive-tuberculosis in breastfeeding mother-infant pairs: An observational pharmacokinetic study. Wellcome Open Research. doi:10.12688/wellcomeopenres.19113.1
Best practices for the care of pregnant people living with TB
Maugans, C., Loveday, M., Hlangu, S., Waitt, C., Van Schalkwyk, M., van de Water, B., . . . Furin, J. (2023). Best practices for the care of pregnant people living with TB. INTERNATIONAL JOURNAL OF TUBERCULOSIS AND LUNG DISEASE, 27(5), 357-366. doi:10.5588/ijtld.23.0031
Relating CYP2B6 Genotype and EFV Resistance Among Women Living With HIV With High Viremia in Uganda: A Nested Cross-Sectional Study.
BUZIBYE, A. L. L. A. N., Wools-Kaloustian, K., Olagunju, A., Twinomuhwezi, E., Yiannoutsos, C., Owen, A., . . . Kiragga, A. (2023). Relating CYP2B6 Genotype and EFV Resistance Among Women Living With HIV With High Viremia in Uganda: A Nested Cross-Sectional Study.. AIDS Research and Therapy. doi:10.1186/s12981-023-00514-2
Relating CYP2B6 genotype and efavirenz resistance among post-partum women living with HIV with high viremia in Uganda: a nested cross-sectional study.
Buzibye, A., Wools-Kaloustian, K., Olagunju, A., Twinomuhwezi, E., Yiannoutsos, C., Owen, A., . . . Kiragga, A. (2023). Relating CYP2B6 genotype and efavirenz resistance among post-partum women living with HIV with high viremia in Uganda: a nested cross-sectional study.. AIDS research and therapy, 20(1), 20. doi:10.1186/s12981-023-00514-2
A commentary on establishing a local centre of excellence for research and training in Pharmacometrics: Lessons from the Pharmacometrics Africa -Uganda Chapter.
A "Bundle of Care" to Improve Anticoagulation Control in Patients Receiving Warfarin in Uganda and South Africa: Protocol for an Implementation Study
Jorgensen, A. L., Orrell, C., Waitt, C., Toh, C. -H., Sekaggya-Wiltshire, C., Hughes, D. A., . . . Pirmohamed, M. (2023). A "Bundle of Care" to Improve Anticoagulation Control in Patients Receiving Warfarin in Uganda and South Africa: Protocol for an Implementation Study. JMIR RESEARCH PROTOCOLS, 12. doi:10.2196/46710
A “Bundle of Care” to Improve Anticoagulation Control in Patients Receiving Warfarin in Uganda and South Africa: Protocol for an Implementation Study (Preprint)
Communication is crucial: Lessons from COVID-19 vaccination and pregnancy
Cole, C., Tsakiroglou, M., & Waitt, C. (2023). Communication is crucial: Lessons from COVID-19 vaccination and pregnancy. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 89(2), 582-593. doi:10.1111/bcp.15578
Pharmacovigilance in low- and middle-income countries: A review with particular focus on Africa
Kiguba, R., Olsson, S., & Waitt, C. (2023). Pharmacovigilance in low- and middle-income countries: A review with particular focus on Africa. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 89(2), 491-509. doi:10.1111/bcp.15193
Establishing a local centre of excellence for research and training in pharmacometrics: Lessons from the Pharmacometrics Africa -Uganda chapter
Pharmacokinetics of drugs used to treat uncomplicated malaria in breastfeeding mother-infant pairs: An observational pharmacokinetic study
Nakijoba, R., Nakayiwa Kawuma, A., Ojara, F. W., Tabwenda, J., Kyeyune, J., Turyahabwe, C., . . . Waitt, C. (2023). Pharmacokinetics of drugs used to treat uncomplicated malaria in breastfeeding mother-infant pairs: An observational pharmacokinetic study. Wellcome Open Research. doi:10.12688/wellcomeopenres.18512.1
It Takes A Village; Involvement of Village Health Teams to Develop Tools and Resources to Communicate about Antiretroviral Use in Pregnancy and Breastfeeding at Community Level in Uganda.
Nalugga, E. A., Kukundakwe, M., Tibakanya, R., Tindyebwa, E., Baluku, W., Mulindwa, K., . . . Waitt, C. (2023). It Takes A Village; Involvement of Village Health Teams to Develop Tools and Resources to Communicate about Antiretroviral Use in Pregnancy and Breastfeeding at Community Level in Uganda.. Wellcome open research, 8, 510. doi:10.12688/wellcomeopenres.19088.1
2022
Clinical trials and pregnancy.
Waitt, C., Astill, D., Zavala, E., Karron, R. A., Faden, R. R., Stratton, P., . . . Clayton, J. A. (2022). Clinical trials and pregnancy.. Communications medicine, 2, 132. doi:10.1038/s43856-022-00198-1
Validation and application of a quantitative LC-MS/MS assay for the analysis of first-line anti-tuberculosis drugs, rifabutin and their metabolites in human breast milk
Zuma, P., Joubert, A., van der Merwe, M., Norman, J., Waitt, C., Court, R., . . . Wiesner, L. (2022). Validation and application of a quantitative LC-MS/MS assay for the analysis of first-line anti-tuberculosis drugs, rifabutin and their metabolites in human breast milk. Journal of Chromatography B, 1211, 123489. doi:10.1016/j.jchromb.2022.123489
Predicting Drug-Drug Interactions between Rifampicin and Ritonavir-Boosted Atazanavir Using PBPK Modelling (vol 61, pg 375, 2022)
Montanha, M. C., Fabrega, F., Howarth, A., Cottura, N., Kinvig, H., Bunglawala, F., . . . Siccardi, M. (2022). Predicting Drug-Drug Interactions between Rifampicin and Ritonavir-Boosted Atazanavir Using PBPK Modelling (vol 61, pg 375, 2022). CLINICAL PHARMACOKINETICS, 61(11), 1641. doi:10.1007/s40262-022-01178-3
A genome-wide association study of plasma concentrations of warfarin enantiomers and metabolites in sub-Saharan black-African patients.
Asiimwe, I. G., Blockman, M., Cohen, K., Cupido, C., Hutchinson, C., Jacobson, B., . . . Pirmohamed, M. (2022). A genome-wide association study of plasma concentrations of warfarin enantiomers and metabolites in sub-Saharan black-African patients.. Frontiers in pharmacology, 13, 967082. doi:10.3389/fphar.2022.967082
72 weeks post-partum follow-up of dolutegravir versus efavirenz initiated in late pregnancy (DolPHIN-2): an open-label, randomised controlled study
Malaba, T. R., Nakatudde, I., Kintu, K., Colbers, A., Chen, T., Reynolds, H., . . . Khoo, S. (2022). 72 weeks post-partum follow-up of dolutegravir versus efavirenz initiated in late pregnancy (DolPHIN-2): an open-label, randomised controlled study. LANCET HIV, 9(8), E534-E543. doi:10.1016/S2352-3018(22)00173-4
Bedaquiline exposure in pregnancy and breastfeeding in women with rifampicin-resistant tuberculosis
Court, R., Gausi, K., Mkhize, B., Wiesner, L., Waitt, C., McIlleron, H., . . . Loveday, M. (2022). Bedaquiline exposure in pregnancy and breastfeeding in women with rifampicin-resistant tuberculosis. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 88(8), 3548-3558. doi:10.1111/bcp.15380
'I fear my partner will abandon me': the intersection of late initiation of antenatal care in pregnancy and poor ART adherence among women living with HIV in South Africa and Uganda
Alhassan, Y., Twimukye, A., Malaba, T., Myer, L., Waitt, C., Lamorde, M., . . . Taegtmeyer, M. (2022). 'I fear my partner will abandon me': the intersection of late initiation of antenatal care in pregnancy and poor ART adherence among women living with HIV in South Africa and Uganda. BMC PREGNANCY AND CHILDBIRTH, 22(1). doi:10.1186/s12884-022-04896-5
<i>"It's only fatness, it doesn't kill"</i>: a qualitative study on perceptions of weight gain from use of dolutegravir-based regimens in women living with HIV in Uganda
Alhassan, Y., Twimukye, A., Malaba, T., Myer, L., Waitt, C., Lamorde, M., . . . Taegtmeyer, M. (2022). <i>"It's only fatness, it doesn't kill"</i>: a qualitative study on perceptions of weight gain from use of dolutegravir-based regimens in women living with HIV in Uganda. BMC WOMENS HEALTH, 22(1). doi:10.1186/s12905-022-01814-x
A randomized comparison of health-related quality of life outcomes of dolutegravir versus efavirenz-based antiretroviral treatment initiated in the third trimester of pregnancy
Ochanda, P. N., Lamorde, M., Kintu, K., Wang, D., Chen, T., Malaba, T., . . . Khoo, S. (2022). A randomized comparison of health-related quality of life outcomes of dolutegravir versus efavirenz-based antiretroviral treatment initiated in the third trimester of pregnancy. AIDS RESEARCH AND THERAPY, 19(1). doi:10.1186/s12981-022-00446-3
High willingness to use injectable antiretroviral therapy among women who have been lost to follow-up from HIV programmes: A nested cross-sectional study
Odongpiny, E. L. A., Cresswell, F., Arinaitwe, A., Nakate, V., Kyenkya, J., Lamorde, M., . . . Kiragga, A. (2022). High willingness to use injectable antiretroviral therapy among women who have been lost to follow-up from HIV programmes: A nested cross-sectional study. HIV MEDICINE, 23(4), 319-323. doi:10.1111/hiv.13260
HIV viral load non-suppression and associated factors among pregnant and postpartum women in rural northeastern South Africa: a cross-sectional survey.
Ngandu, N. K., Lombard, C. J., Mbira, T. E., Puren, A., Waitt, C., Prendergast, A. J., . . . Goga, A. E. (2022). HIV viral load non-suppression and associated factors among pregnant and postpartum women in rural northeastern South Africa: a cross-sectional survey.. BMJ open, 12(3), e058347. doi:10.1136/bmjopen-2021-058347
PBPK MODELING OF LONG-ACTING INJECTABLE CABOTEGRAVIR IN PREGNANCY
Atoyebi, S., Bunglawala, F., Cottura, N., Camotti-Montanha, M., Siccardi, M., & Waitt, C. (2022). PBPK MODELING OF LONG-ACTING INJECTABLE CABOTEGRAVIR IN PREGNANCY. In Fazila Bunglawala. Conference on Retroviruses and Opportunistic Infections.
Twice neglected? Neglected diseases in neglected populations
Weld, E. D., Waitt, C., Barnes, K., & Garcia Bournissen, F. (2022). Twice neglected? Neglected diseases in neglected populations. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 88(2), 367-373. doi:10.1111/bcp.15148
Physiologically based pharmacokinetic modelling of long-acting rilpivirine in pregnancy
Atoyebi, S., Granana-Castillo, S., Siccardi, M., & Waitt, C. (2022). Physiologically based pharmacokinetic modelling of long-acting rilpivirine in pregnancy. In JOURNAL OF THE INTERNATIONAL AIDS SOCIETY Vol. 25 (pp. 186-187). Retrieved from https://www.webofscience.com/
Stable warfarin dose prediction in sub-Saharan African patients: A machine-learning approach and external validation of a clinical dose-initiation algorithm
Asiimwe, I. G., Blockman, M., Cohen, K., Cupido, C., Hutchinson, C., Jacobson, B., . . . Pirmohamed, M. (2022). Stable warfarin dose prediction in sub-Saharan African patients: A machine-learning approach and external validation of a clinical dose-initiation algorithm. CPT-PHARMACOMETRICS & SYSTEMS PHARMACOLOGY, 11(1), 20-29. doi:10.1002/psp4.12740
“Ethical issues in therapeutic use and research in pregnant and breastfeeding women”
Weld, E. D., Bailey, T. C., & Waitt, C. (2022). Ethical issues in therapeutic use and research in pregnant and breastfeeding women. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 88(1), 7-21. doi:10.1111/bcp.14914
2021
An open-label, randomized, single intravenous dosing study to investigate the effect of fixed-dose combinations of tenofovir/lamivudine or atazanavir/ritonavir on the pharmacokinetics of remdesivir in Ugandan healthy volunteers (RemTLAR)
Walimbwa, S. I., Kaboggoza, J. P., Waitt, C., Byakika-Kibwika, P., D’Avolio, A., & Lamorde, M. (2021). An open-label, randomized, single intravenous dosing study to investigate the effect of fixed-dose combinations of tenofovir/lamivudine or atazanavir/ritonavir on the pharmacokinetics of remdesivir in Ugandan healthy volunteers (RemTLAR). Trials, 22(1). doi:10.1186/s13063-021-05752-1
Bedaquiline exposure in pregnancy and breastfeeding in women with rifampicin-resistant tuberculosis
Developing and Validating a Clinical Warfarin Dose-Initiation Model for Black-African Patients in South Africa and Uganda (vol 109, pg 1564, 2021)
Asiimwe, I. G., Waitt, C., Sekaggya-Wiltshire, C., Hutchinson, C., Okello, E., Zhang, E. J., . . . Pirmohamed, M. (2021). Developing and Validating a Clinical Warfarin Dose-Initiation Model for Black-African Patients in South Africa and Uganda (vol 109, pg 1564, 2021). CLINICAL PHARMACOLOGY & THERAPEUTICS, 110(5), 1402. doi:10.1002/cpt.2395
Predicting Drug-Drug Interactions between Rifampicin and Ritonavir-Boosted Atazanavir Using PBPK Modelling
Montanha, M. C., Fabrega, F., Howarth, A., Cottura, N., Kinvig, H., Bunglawala, F., . . . Siccardi, M. (2021). Predicting Drug-Drug Interactions between Rifampicin and Ritonavir-Boosted Atazanavir Using PBPK Modelling. CLINICAL PHARMACOKINETICS. doi:10.1007/s40262-021-01067-1
Pharmacovigilance in Low and Middle-Income Countries: A review with particular focus on Africa
Twice Neglected? Neglected Diseases in Neglected Populations
Infant exposure to dolutegravir through placental and breastmilk transfer: a population pharmacokinetic analysis of DolPHIN-1.
Dickinson, L., Walimbwa, S., Singh, Y., Kaboggoza, J., Kintu, K., Sihlangu, M., . . . Orrell, C. (2021). Infant Exposure to Dolutegravir Through Placental and Breast Milk Transfer: A Population Pharmacokinetic Analysis of DolPHIN-1. CLINICAL INFECTIOUS DISEASES, 73(5), E1200-E1207. doi:10.1093/cid/ciaa1861
Improving anticoagulation in sub-Saharan Africa: What are the challenges and how can we overcome them?
Mouton, J. P., Blockman, M., Sekaggya-Wiltshire, C., Semakula, J., Waitt, C., Pirmohamed, M., & Cohen, K. (2021). Improving anticoagulation in sub-Saharan Africa: What are the challenges and how can we overcome them?. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 87(8), 3056-3068. doi:10.1111/bcp.14768
Optimizing pharmacology studies in pregnant and lactating women using lessons from HIV: a consensus statement
Eke, A. C., Olagunju, A., Momper, J., Penazzato, M., Abrams, E. J., Best, B. M., . . . Colbers, A. (2021). Optimizing Pharmacology Studies in Pregnant and Lactating Women Using Lessons From HIV: A Consensus Statement. CLINICAL PHARMACOLOGY & THERAPEUTICS, 110(1), 36-48. doi:10.1002/cpt.2048
Developing and Validating a Clinical Warfarin Dose-Initiation Model for Black-African Patients in South Africa and Uganda
Asiimwe, I. G., Waitt, C., Sekaggya-Wiltshire, C., Hutchinson, C., Okello, E., Zhang, E. J., . . . Pirmohamed, M. (2021). Developing and Validating a Clinical Warfarin Dose-Initiation Model for Black-African Patients in South Africa and Uganda. CLINICAL PHARMACOLOGY & THERAPEUTICS, 109(6), 1564-1574. doi:10.1002/cpt.2128
An open-label, randomized, single intravenous dosing study to investigate the effect of fixed dose combinations of tenofovir/lamivudine or atazanavir/ritonavir on the pharmacokinetics of remdesivir in Ugandan healthy volunteers (RemTLAR)
Anti‐infective Dosing in Special Populations: Pregnancy
Hazenberg, P., Navaratnam, K., Busuulwa, P., & Waitt, C. (2021). Anti-Infective Dosing in Special Populations: Pregnancy. CLINICAL PHARMACOLOGY & THERAPEUTICS, 109(4), 977-986. doi:10.1002/cpt.2192
Anticoagulation in sub-Saharan Africa: Are Direct Oral Anticoagulants the answer? A review of lessons learnt from warfarin
Semakula, J., Kisa, G., Mouton, J., Cohen, K., Blockman, M., Pirmohamed, M., . . . Waitt, C. (2021). Anticoagulation in sub-Saharan Africa: Are Direct Oral Anticoagulants the answer? A review of lessons learnt from warfarin. British Journal of Clinical Pharmacology. doi:10.1111/bcp.14796
Advancing knowledge in perinatal HIV treatment.
Waitt, C., Myer, L., & Khoo, S. (2021). Advancing knowledge in perinatal HIV treatment.. The lancet. HIV, 8(3), e124-e125. doi:10.1016/s2352-3018(20)30306-4
2020
Validation of a UHPLC-MS/MS Method to Quantify Twelve Antiretroviral Drugs within Peripheral Blood Mononuclear Cells from People Living with HIV
De Nicolo, A., Ianniello, A., Ferrara, M., Avataneo, V., Cusato, J., Antonucci, M., . . . D'Avolio, A. (2021). Validation of a UHPLC-MS/MS Method to Quantify Twelve Antiretroviral Drugs within Peripheral Blood Mononuclear Cells from People Living with HIV. PHARMACEUTICALS, 14(1). doi:10.3390/ph14010012
Community acceptability of dolutegravir-based HIV treatment in women: a qualitative study in South Africa and Uganda
Alhassan, Y., Twimukye, A., Malaba, T., Orrell, C., Myer, L., Waitt, C., . . . Taegtmeyer, M. (2020). Community acceptability of dolutegravir-based HIV treatment in women: a qualitative study in South Africa and Uganda. BMC Public Health, 20(1). doi:10.1186/s12889-020-09991-w
Onsite Mentorship Model for Isolation and Management of Viral Hemorrhagic Fever Syndromes at a Ugandan Hospital
Waitt, P., Nakato, S., Ayebare, R., Ssekabira, U., Nanyondo, J., Waitt, C., . . . Lamorde, M. (2020). Onsite Mentorship Model for Isolation and Management of Viral Hemorrhagic Fever Syndromes at a Ugandan Hospital. In INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY Vol. 41 (pp. S491-S492). doi:10.1017/ice.2020.1167
Engendering health systems in response to national rollout of dolutegravir-based regimens among women of childbearing potential: a qualitative study with stakeholders in South Africa and Uganda
Alhassan, Y., Twimukye, A., Malaba, T., Orrell, C., Myer, L., Waitt, C., . . . Taegtmeyer, M. (2020). Engendering health systems in response to national rollout of dolutegravir-based regimens among women of childbearing potential: a qualitative study with stakeholders in South Africa and Uganda. BMC HEALTH SERVICES RESEARCH, 20(1). doi:10.1186/s12913-020-05580-0
Development and validation of a UHPLC-MS/MS method for quantification of the prodrug remdesivir and its metabolite GS-441524: a tool for clinical pharmacokinetics of SARS-CoV-2/COVID-19 and Ebola virus disease
Avataneo, V., de Nicolò, A., Cusato, J., Antonucci, M., Manca, A., Palermiti, A., . . . D’Avolio, A. (2020). Development and validation of a UHPLC-MS/MS method for quantification of the prodrug remdesivir and its metabolite GS-441524: a tool for clinical pharmacokinetics of SARS-CoV-2/COVID-19 and Ebola virus disease. Journal of Antimicrobial Chemotherapy. doi:10.1093/jac/dkaa152
COMPARATIVE QUALITY OF LIFE OUTCOMES OF DOLUTEGRAVIR-BASED OR EFAVIRENZ-BASED ANTIRETOVIRAL TREATMENT IN PREGNANCY FOR LATE PRESENTORS BETWEEN THE 3RD TRIAL-MESTER AND 48 WEEKS POSTPARTUM
Perez Nicholas, O., Lamorde, M., Kintu, K., Wang, D., Chen, T., Malaba, T., . . . Khoo, S. (2020). COMPARATIVE QUALITY OF LIFE OUTCOMES OF DOLUTEGRAVIR-BASED OR EFAVIRENZ-BASED ANTIRETOVIRAL TREATMENT IN PREGNANCY FOR LATE PRESENTORS BETWEEN THE 3RD TRIAL-MESTER AND 48 WEEKS POSTPARTUM. In VALUE IN HEALTH Vol. 23 (pp. S184). Retrieved from https://www.webofscience.com/
Dolutegravir versus efavirenz when starting HIV therapy in late pregnancy: a randomised controlled trial
Kintu, K., Malaba, T., Nakibuka, J., Papamichael, C., Colbers, A., Byrne, K., . . . Khoo, S. (2020). Dolutegravir versus efavirenz when starting HIV therapy in late pregnancy: a randomised controlled trial. The Lancet HIV, 7(5), e332-e339. doi:10.1016/s2352-3018(20)30050-3
PIN90 COMPARATIVE QUALITY OF LIFE OUTCOMES OF DOLUTEGRAVIR-BASED OR EFAVIRENZ-BASED ANTIRETOVIRAL TREATMENT IN PREGNANCY FOR LATE PRESENTORS BETWEEN THE 3RD TRIAL-MESTER AND 48 WEEKS POSTPARTUM
Perez Nicholas, O., Lamorde, M., Kintu, K., Wang, D., Chen, T., Malaba, T., . . . Khoo, S. (2020). PIN90 COMPARATIVE QUALITY OF LIFE OUTCOMES OF DOLUTEGRAVIR-BASED OR EFAVIRENZ-BASED ANTIRETOVIRAL TREATMENT IN PREGNANCY FOR LATE PRESENTORS BETWEEN THE 3RD TRIAL-MESTER AND 48 WEEKS POSTPARTUM. Value in Health, 23, S184. doi:10.1016/j.jval.2020.04.553
A cross-sectional evaluation of five warfarin anticoagulation services in Uganda and South Africa
Semakula, J. R., Mouton, J. P., Jorgensen, A., Hutchinson, C., Allie, S., Semakula, L., . . . Cohen, K. (2020). A cross-sectional evaluation of five warfarin anticoagulation services in Uganda and South Africa. PLOS ONE, 15(1). doi:10.1371/journal.pone.0227458
2019
Pharmacokinetics of maraviroc in plasma and breastmilk in a treatment-experienced perinatally HIV-1-infected woman.
Feiterna-Sperling, C., Krüger, R., Amara, A., Khoo, S., & Waitt, C. (2019). Pharmacokinetics of maraviroc in plasma and breastmilk in a treatment-experienced perinatally HIV-1-infected woman.. AIDS (London, England), 33(15), 2443-2444. doi:10.1097/qad.0000000000002360
Inclusion of pregnant women in antiretroviral drug research: what is needed to move forwards?
Fairlie, L., Waitt, C., Lockman, S., Moorehouse, M., Abrams, E., Clayden, P., . . . Cherisch, M. (2019). Inclusion of pregnant women in antiretroviral drug research: what is needed to move forwards?. Journal of the International AIDS Society. doi:10.1002/jia2.25372
Pharmacokinetics of maraviroc in plasma and breastmilk in a treatment-experienced perinatally HIV-1-infected woman
Feiterna-Sperling, C., Krueger, R., Amara, A., Khoo, S., & Waitt, C. (2019). Pharmacokinetics of maraviroc in plasma and breastmilk in a treatment-experienced perinatally HIV-1-infected woman. AIDS, 33(15), 2443-2444. doi:10.1097/QAD.0000000000002360
Reply to Banda et al., "Interpretation of Drug Interactions between Dolutegravir and Artemether-Lumefantrine or Artesunate-Amodiaquine"
Walimbwa, S., Lamorde, M., Waitt, C., Amara, A., & Khoo, S. (2019). Reply to Banda et al., "Interpretation of Drug Interactions between Dolutegravir and Artemether-Lumefantrine or Artesunate-Amodiaquine". ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 63(6). doi:10.1128/AAC.00593-19
Transmission of CMV, HTLV-1, and HIV through breastmilk
Prendergast, A. J., Goga, A. E., Waitt, C., Gessain, A., Taylor, G. P., Rollins, N., . . . Van de Perre, P. (2019). Transmission of CMV, HTLV-1, and HIV through breastmilk. LANCET CHILD & ADOLESCENT HEALTH, 3(4), 264-273. doi:10.1016/S2352-4642(19)30024-0
Pharmacokinetics, Placental and Breastmilk Transfer of Antiretroviral Drugs in Pregnant and Lactating Women Living with HIV.
Hodel, E. M., Marzolini, C., Waitt, C., & Rakhmanina, N. (2019). Pharmacokinetics, Placental and Breastmilk Transfer of Antiretroviral Drugs in Pregnant and Lactating Women Living with HIV.. Current Pharmaceutical Design. doi:10.2174/1381612825666190320162507
Impact of pharmacogenetics and pregnancy on tenofovir and emtricitabine pharmacokinetics
Gini, J., Olagunju, A., Dickinson, L., Waitt, C., Neary, M., Else, L. J., . . . Khoo, S. (2019). Impact of pharmacogenetics and pregnancy on tenofovir and emtricitabine pharmacokinetics. PHARMACOGENOMICS, 20(4), 217-224. doi:10.2217/pgs-2018-0111
DRUG INTERACTIONS BETWEEN DOLUTEGRAVIR AND ARTEMETHER-LUMEFANTRINE OR ARTESUNATE-AMODIAQUINE.
Walimbwa, S. I., Lamorde, M., Waitt, C., Kaboggoza, J., Else, L., Byakika-Kibwika, P., . . . Khoo, S. H. (2019). Drug Interactions between Dolutegravir and Artemether-Lumefantrine or Artesunate-Amodiaquine. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 63(2). doi:10.1128/AAC.01310-18
Safety and pharmacokinetics of dolutegravir in pregnant mothers with HIV infection and their neonates: A randomised trial (DolPHIN-1 study)
Waitt, C., Orrell, C., Walimbwa, S., Singh, Y., Kintu, K., Simmons, B., . . . Khoo, S. (2019). Safety and pharmacokinetics of dolutegravir in pregnant mothers with HIV infection and their neonates: A randomised trial (DolPHIN-1 study). PLOS MEDICINE, 16(9). doi:10.1371/journal.pmed.1002895
2018
Validation and clinical application of a novel LC-MS method for quantification of dolutegravir in breast milk
Gini, J., Penchala, S. D., Amara, A., Challenger, E., Egan, D., Waitt, C., . . . Else, L. J. (2018). Validation and clinical application of a novel LC-MS method for quantification of dolutegravir in breast milk. BIOANALYSIS, 10(23), 1933-1945. doi:10.4155/bio-2018-0085
High prevalence and long duration of nervous system and psychiatric adverse drug reactions in Ugandan patients taking efavirenz 600 mg daily
Seden, K., Kiiza, D., Laker, E., Arinaitwe, W. J., Waitt, C., Lamorde, M., & Khoo, S. (2018). High prevalence and long duration of nervous system and psychiatric adverse drug reactions in Ugandan patients taking efavirenz 600 mg daily. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 73(11), 3158-3161. doi:10.1093/jac/dky298
Does U=U for breastfeeding mothers and infants? Breastfeeding by mothers on effective treatment for HIV infection in high-income settings
Waitt, C. J., Lowe, N., van de Perre, P., Lyon, F., Loutfy, M., & Aebi-Popp, K. (2018). Does U=U for breastfeeding mothers and infants? Breastfeeding by mothers on effective treatment for HIV infection in high-income settings. The Lancet HIV, 5(9), E531-E536. doi:10.1016/S2352-3018(18)30098-5
DolPHIN-1: Randomised controlled trial of dolutegravir (DTG)- versus efavirenz (EFV)-based therapy in mothers initiating antiretroviral treatment in late pregnancy
Orrell, C., Kintu, K., Coombs, J. A., Amara, A., Myer, L., Kaboggoza, J., . . . Lamorde, M. (2018). DolPHIN-1: Randomised controlled trial of dolutegravir (DTG)- versus efavirenz (EFV)-based therapy in mothers initiating antiretroviral treatment in late pregnancy. In JOURNAL OF THE INTERNATIONAL AIDS SOCIETY Vol. 21 (pp. 166). Retrieved from https://www.webofscience.com/
Drug Interactions Between Dolutegravir and Artemether-Lumefantrine or Artesunate-Amodiaquine
Walimbwa, S., Lamorde, M., Waitt, C., Kaboggoza, J., Else, L., Byakika-Kibwika, P., . . . Khoo, S. (2018). Drug Interactions Between Dolutegravir and Artemether-Lumefantrine or Artesunate-Amodiaquine. doi:10.1101/351684
Plasma and breast milk pharmacokinetics of emtricitabine, tenofovir and lamivudine using dried blood and breast milk spots in nursing African mother-infant pairs.
Waitt, C., Olagunju, A., Nakalema, S., Kyohaire, I., Owen, A., Lamorde, M., & Khoo, S. (2018). Plasma and Breast Milk Pharmacokinetics of Emtricitabine, Tenofovir and Lamivudine Using Dried Blood and Breast Milk Spots in Nursing African Mother-Infant Pairs. Journal of Antimicrobial Chemotherapy, 73(4), 1013-1019. doi:10.1093/jac/dkx507
2017
Development, validation and clinical application of a method for the simultaneous quantification of lamivudine, emtricitabine and tenofovir in dried blood and dried breast milk spots using LC-MS/MS
Waitt, C., Penchala, S. D., Olagunju, A., Amara, A., Else, L., Lamorde, M., & Khoo, S. (2017). Development, validation and clinical application of a method for the simultaneous quantification of lamivudine, emtricitabine and tenofovir in dried blood and dried breast milk spots using LC-MS/MS. Journal of Chromatography B, 1060, 300-307. doi:10.1016/j.jchromb.2017.06.012
2016
Dosing antiretroviral medication when crossing time zones: a review
Lewis, J. M., Volny-Anne, A., Waitt, C., Boffito, M., & Khoo, S. (2016). Dosing antiretroviral medication when crossing time zones: a review. AIDS, 30(2), 267-271. doi:10.1097/QAD.0000000000000920
Spontaneous adverse drug reaction reports for neonates and infants in the UK 2001-2010: content and utility analysis
Hawcutt, D. B., Russell, N. J., Maqsood, H., Kouranloo, K., Gomberg, S., Waitt, C., . . . Turner, M. A. (2016). Spontaneous adverse drug reaction reports for neonates and infants in the UK 2001-2010: content and utility analysis. British journal of clinical pharmacology, 82(06), 1601-1612. doi:10.1111/bcp.13067
2015
Monocyte unresponsiveness and impaired IL1β, TNFα and IL7 production are associated with a poor outcome in Malawian adults with pulmonary tuberculosis
Waitt, C. J., Banda, P., Glennie, S., Kampmann, B., Squire, S. B., Pirmohamed, M., & Heyderman, R. S. (2015). Monocyte unresponsiveness and impaired IL1β, TNFα and IL7 production are associated with a poor outcome in Malawian adults with pulmonary tuberculosis. BMC Infectious Diseases, 15. doi:10.1186/s12879-015-1274-4
Validation and clinical application of a method to quantify nevirapine in dried blood spots and dried breast-milk spots
Olagunju, A., Amara, A., Waitt, C., Else, L., Penchala, S. D., Bolaji, O., . . . Khoo, S. (2015). Validation and clinical application of a method to quantify nevirapine in dried blood spots and dried breast-milk spots. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 70(10), 2816-2822. doi:10.1093/jac/dkv174
Breast Milk Pharmacokinetics of Efavirenz and Breastfed Infants' Exposure in Genetically Defined Subgroups of Mother-Infant Pairs: An Observational Study
Olagunju, A., Bolaji, O., Amara, A., Waitt, C., Else, L., Adejuyigbe, E., . . . Owen, A. (2015). Breast Milk Pharmacokinetics of Efavirenz and Breastfed Infants' Exposure in Genetically Defined Subgroups of Mother-Infant Pairs: An Observational Study. Clin Infect Dis, 61(3), 453-463. doi:10.1093/cid/civ317
Is infant exposure to antiretroviral drugs during breastfeeding quantitatively important? A systematic review and meta-analysis of pharmacokinetic studies
Waitt, C. J., Garner, P., Bonnett, L. J., Khoo, S. H., & Else, L. J. (2015). Is infant exposure to antiretroviral drugs during breastfeeding quantitatively important? A systematic review and meta-analysis of pharmacokinetic studies. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 70(7), 1928-1941. doi:10.1093/jac/dkv080
Development, validation and clinical application of a novel method for the quantification of efavirenz in dried breast milk spots using LC-MS/MS
Olagunju, A., Bolaji, O. O., Amara, A., Waitt, C., Else, L., Soyinka, J., . . . Khoo, S. (2015). Development, validation and clinical application of a novel method for the quantification of efavirenz in dried breast milk spots using LC-MS/MS. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 70(2), 555-561. doi:10.1093/jac/dku420
Development, validation and clinical application of a novel method for the quantification of efavirenz in dried breast milk spots using LC-MS/MS.
Olagunju, A., Bolaji, O. O., Amara, A., Waitt, C., Else, L., Soyinka, J., . . . Khoo, S. (2015). Development, validation and clinical application of a novel method for the quantification of efavirenz in dried breast milk spots using LC-MS/MS.. The Journal of antimicrobial chemotherapy, 70(2), 555-561.
2014
Sepsis carries a high mortality among hospitalised adults in Malawi in the era of antiretroviral therapy scale-up: A longitudinal cohort study
Waitt, P. I., Mukaka, M., Goodson, P., SimuKonda, F. D., Waitt, C. J., Feasey, N., . . . Heyderman, R. S. (2014). Sepsis carries a high mortality among hospitalised adults in Malawi in the era of antiretroviral therapy scale-up: A longitudinal cohort study. Journal of Infection, 70(1), 11-19. doi:10.1016/j.jinf.2014.07.004
2013
Severity Assessment of Lower Respiratory Tract Infection in Malawi: Derivation of a Novel Index (SWAT-Bp) Which Outperforms CRB-65
Birkhamshaw, E., Waitt, C. J., Innes, M., & Waitt, P. I. (2013). Severity Assessment of Lower Respiratory Tract Infection in Malawi: Derivation of a Novel Index (SWAT-Bp) Which Outperforms CRB-65. PLOS ONE, 8(12). doi:10.1371/journal.pone.0082178
The effect of a tuberculosis chest X-ray image reference set on non-expert reader performance
Waitt, C. J., Joekes, E. C., Jesudason, N., Waitt, P. I., Goodson, P., Likumbo, G., . . . Squire, S. B. (2013). The effect of a tuberculosis chest X-ray image reference set on non-expert reader performance. EUROPEAN RADIOLOGY, 23(9), 2459-2468. doi:10.1007/s00330-013-2840-z
2011
Early Deaths During Tuberculosis Treatment Are Associated With Depressed Innate Responses, Bacterial Infection, and Tuberculosis Progression
Waitt, C. J., Banda, N. P. K., White, S. A., Kampmann, B., Kumwenda, J., Heyderman, R. S., . . . Squire, S. B. (2011). Early Deaths During Tuberculosis Treatment Are Associated With Depressed Innate Responses, Bacterial Infection, and Tuberculosis Progression. JOURNAL OF INFECTIOUS DISEASES, 204(3), 358-362. doi:10.1093/infdis/jir265
A systematic review of risk factors for death in adults during and after tuberculosis treatment
Waitt, C. J., & Squire, S. B. (2011). A systematic review of risk factors for death in adults during and after tuberculosis treatment. INTERNATIONAL JOURNAL OF TUBERCULOSIS AND LUNG DISEASE, 15(7), 871-885. doi:10.5588/ijtld.10.0352
Investigation into Early Mortality in Malawian Adults treated for Pulmonary Tuberculosis
Waitt, C. (2011). Investigation into Early Mortality in Malawian Adults treated for Pulmonary Tuberculosis. (PhD Thesis, The University of Liverpool).
2008
Effect of atazanavir and ritonavir on the differentiation and adipokine secretion of human subcutaneous and omental preadipocytes
Jones, S. P., Waitt, C., Sutton, R., Back, D. J., & Pirmohamed, M. (2008). Effect of atazanavir and ritonavir on the differentiation and adipokine secretion of human subcutaneous and omental preadipocytes. AIDS, 22(11), 1293-1298. doi:10.1097/QAD.0b013e3283021a4f
Effect of atazanavir and ritonavir on the differentiation and adipokine secretion of human subcutaneous and omental preadipocytes
Jones, S. P., Waitt, C., Sutton, R., Back, D. J., & Pirmohamed, M. (2008). Effect of atazanavir and ritonavir on the differentiation and adipokine secretion of human subcutaneous and omental preadipocytes. AIDS, 22(11), 1293-1298. doi:10.1097/qad.0b013e3283021a4f
2007
A rapid and sensitive HPLC-MS method for the detection of plasma and cellular rifampicin
Hartkoorn, R. C., Khoo, S., Back, D. J., Tjia, J. F., Waitt, C. J., Chaponda, M., . . . Ward, S. A. (2007). A rapid and sensitive HPLC-MS method for the detection of plasma and cellular rifampicin. JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 857(1), 76-82. doi:10.1016/j.jchromb.2007.07.005
2005
A retained intravascular medical device and <i>Streptococcus bovis</i> infection, providing early diagnosis of an occult malignancy
Beadsworth, M., Waitt, C., Jenkins, N., Amadi, A., Nye, F., & Beeching, N. (2005). A retained intravascular medical device and <i>Streptococcus bovis</i> infection, providing early diagnosis of an occult malignancy. JOURNAL OF INFECTION, 50(2), 165-167. doi:10.1016/j.jinf.2004.08.024
2004
Intravenous therapy.
Waitt, C., Waitt, P., & Pirmohamed, M. (2004). Intravenous therapy.. Postgraduate medical journal, 80(939), 1-6. doi:10.1136/pmj.2003.010421
Intravenous therapy
Waitt, C., Waitt, P., & Pirmohamed, M. (2004). Intravenous therapy. POSTGRADUATE MEDICAL JOURNAL, 80(939), 1-6. doi:10.1136/pmj.2003.010421