Publications
2021
Uterine Excitability and Ion Channels and Their Changes with Gestation and Hormonal Environment
Wray, S., & Arrowsmith, S. (2021). Uterine Excitability and Ion Channels and Their Changes with Gestation and Hormonal Environment. ANNUAL REVIEW OF PHYSIOLOGY, VOL 83, 83, 331-357. doi:10.1146/annurev-physiol-032420-035509
The Physiological Mechanisms of the Sex-Based Difference in Outcomes of COVID19 Infection
Wray, S., & Arrowsmith, S. (2021). The Physiological Mechanisms of the Sex-Based Difference in Outcomes of COVID19 Infection. FRONTIERS IN PHYSIOLOGY, 12. doi:10.3389/fphys.2021.627260
Identification and validation of suitable reference genes for quantitative real-time PCR gene expression analysis in pregnant human myometrium
Arrowsmith, S. (2021). Identification and validation of suitable reference genes for quantitative real-time PCR gene expression analysis in pregnant human myometrium. Molecular Biology Reports. doi:10.1007/s11033-020-06066-2
2020
Using pyrene to probe the effects of poloxamer stabilisers on internal lipid microenvironments in solid lipid nanoparticles
Taylor, J. M., Scale, K., Arrowsmith, S., Sharp, A., Flynn, S., Rannard, S., & McDonald, T. O. (2020). Using pyrene to probe the effects of poloxamer stabilisers on internal lipid microenvironments in solid lipid nanoparticles. NANOSCALE ADVANCES, 2(12), 5572-5577. doi:10.1039/d0na00582g
Gestational and Hormonal Effects on Magnesium Sulfate's Ability to Inhibit Mouse Uterine Contractility
Osaghae, B. E., Arrowsmith, S., & Wray, S. (2020). Gestational and Hormonal Effects on Magnesium Sulfate's Ability to Inhibit Mouse Uterine Contractility. REPRODUCTIVE SCIENCES, 27(8), 1570-1579. doi:10.1007/s43032-020-00185-8
Comparison of the myometrial transcriptome from singleton and twin pregnancies by RNA-Seq
Arrowsmith, S., Fang, Y., & Sharp, A. (2020). Comparison of the myometrial transcriptome from singleton and twin pregnancies by RNA-Seq. PLOS ONE, 15(1). doi:10.1371/journal.pone.0227882
2019
Oxytocin and vasopressin signalling and myometrial contraction
Arrowsmith, S. (2019). Oxytocin and vasopressin signalling and myometrial contraction. Current opinion in physiology. doi:10.1016/j.cophys.2019.10.006
Gestational and Hormonal Effects on Magnesium Sulfate's Ability to Inhibit Mouse Uterine Contractility.
Osaghae, B. E., Arrowsmith, S., & Wray, S. (2019). Gestational and Hormonal Effects on Magnesium Sulfate's Ability to Inhibit Mouse Uterine Contractility.. Reproductive sciences (Thousand Oaks, Calif.), 1933719119828089. doi:10.1177/1933719119828089
Novel analogues of oxytocin and vasopressin to modulate human myometrial contraction
Arrowsmith, S. (2019). Novel analogues of oxytocin and vasopressin to modulate human myometrial contraction. In ACTA PHYSIOLOGICA Vol. 227 (pp. 23). Retrieved from https://www.webofscience.com/
2018
Contractility Measurements of Human Uterine Smooth Muscle to Aid Drug Development
Arrowsmith, S., Keov, P., Muttenthaler, M., & Gruber, C. W. (2018). Contractility Measurements of Human Uterine Smooth Muscle to Aid Drug Development. JOVE-JOURNAL OF VISUALIZED EXPERIMENTS, (131). doi:10.3791/56639
2017
Subtle modifications to oxytocin produce ligands that retain potency and improved selectivity across species.
Muttenthaler, M., Andersson, Å., Vetter, I., Menon, R., Busnelli, M., Ragnarsson, L., . . . Alewood, P. F. (2017). Subtle modifications to oxytocin produce ligands that retain potency and improved selectivity across species.. Science signaling, 10(508). doi:10.1126/scisignal.aan3398
Encyclopedia of signalling molecules: Oxytocin receptor
Arrowsmith, S. (2017). Encyclopedia of signalling molecules: Oxytocin receptor. In S. Choi (Ed.), Encyclopedia of Signaling Molecules. Springer.
Development of a human vasopressin V1a-receptor antagonist from an evolutionary-related insect neuropeptide
Wray, S. C., & arrowsmith, S. (2017). Development of a human vasopressin V1a-receptor antagonist from an evolutionary-related insect neuropeptide. Scientific Reports. doi:10.1038/srep41002
2016
The combination tocolytic effect of magnesium sulfate and an oxytocin receptor antagonist in myometrium from singleton and twin pregnancies
Arrowsmith, S., Neilson, J., & Wray, S. (2016). The combination tocolytic effect of magnesium sulfate and an oxytocin receptor antagonist in myometrium from singleton and twin pregnancies. AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY, 215(6). doi:10.1016/j.ajog.2016.08.015
Ethnobotanical survey of <i>Rinorea dentata</i> (Violaceae) used in South-Western Nigerian ethnomedicine and detection of cyclotides
Attah, A. F., Hellinger, R., Sonibare, M. A., Moody, J. O., Arrowsmith, S., Wray, S., & Gruber, C. W. (2016). Ethnobotanical survey of <i>Rinorea dentata</i> (Violaceae) used in South-Western Nigerian ethnomedicine and detection of cyclotides. JOURNAL OF ETHNOPHARMACOLOGY, 179, 83-91. doi:10.1016/j.jep.2015.12.038
Differing In Vitro Potencies of Tocolytics and Progesterone in Myometrium From Singleton and Twin Pregnancies
Arrowsmith, S., Neilson, J., Bricker, L., & Wray, S. (2016). Differing In Vitro Potencies of Tocolytics and Progesterone in Myometrium From Singleton and Twin Pregnancies. REPRODUCTIVE SCIENCES, 23(1), 98-111. doi:10.1177/1933719115597788
Expression and function of vasopressin receptor subtypes in human myometrium: implications for effective tocolysis
Arrowsmith, S., Taylor, O., Muttenthaler, M., & Wray, S. (2016). Expression and function of vasopressin receptor subtypes in human myometrium: implications for effective tocolysis. In ACTA PHYSIOLOGICA Vol. 217 (pp. 21-22). Retrieved from https://www.webofscience.com/
MIKLOS BODANSZKY AWARD LECTURE PROBING THE FUNCTIONAL COMPLEXITY OF ANCIENT OXYTOCIN IN HEALTH AND DISEASE
Muttenthaler, M., Andersson, A., Ragnarsson, L., Vetter, I., Busnelli, M., Chini, B., . . . Alewood, P. F. (2016). MIKLOS BODANSZKY AWARD LECTURE PROBING THE FUNCTIONAL COMPLEXITY OF ANCIENT OXYTOCIN IN HEALTH AND DISEASE. In JOURNAL OF PEPTIDE SCIENCE Vol. 22 (pp. S6-S8). Retrieved from https://www.webofscience.com/
2015
Hypoxia-induced force increase (HIFI) is a novel mechanism underlying the strengthening of labor contractions, produced by hypoxic stresses.
Alotaibi, M., Arrowsmith, S., & Wray, S. (2015). Hypoxia-induced force increase (HIFI) is a novel mechanism underlying the strengthening of labor contractions, produced by hypoxic stresses.. Proceedings of the National Academy of Sciences of the United States of America, 112(31), 9763-9768. doi:10.1073/pnas.1503497112
Progress in understanding electro-mechanical signalling in the myometrium
Wray, S., Burdyga, T., Noble, D., Noble, K., Borysova, L., & Arrowsmith, S. (2015). Progress in understanding electro-mechanical signalling in the myometrium. ACTA PHYSIOLOGICA, 213(2), 417-431. doi:10.1111/apha.12431
Magnesium sulphate inhibits spontaneous and oxytocin induced contractions of mouse myometrium
Osaghae, B., Arrowsmith, S., & Wray, S. (2015). Magnesium sulphate inhibits spontaneous and oxytocin induced contractions of mouse myometrium. In ACTA PHYSIOLOGICA Vol. 215 (pp. 7). Retrieved from https://www.webofscience.com/
Re-Examining the Importance of Vasopressin Receptors in Myometrial Contraction.
Arrowsmith, S., Wray, S., & Muttenthaler, M. (2015). Re-Examining the Importance of Vasopressin Receptors in Myometrial Contraction.. In REPRODUCTIVE SCIENCES Vol. 22 (pp. 332A). Retrieved from https://www.webofscience.com/
2014
Do we now understand the SR in the myometrium?
Wray, S., Burdyga, T., Noble, D., Borysova, L., Arrowsmith, S., & Noble, K. (2014). Do we now understand the SR in the myometrium?. In ACTA PHYSIOLOGICA Vol. 211 (pp. 52). Retrieved from https://www.webofscience.com/
Myometrial physiology - time to translate
Arrowsmith, S., Kendrick, A., Hanley, J. A., Noble, K., & Wray, S. (2014). Myometrial physiology - time to translate. Exp Physiol.
Oxytocin Reduces the Tocolytic Effect of Magnesium Sulphate in Human Myometrium
Arrowsmith, S., Neilson, J., & Wray, S. (2014). Oxytocin Reduces the Tocolytic Effect of Magnesium Sulphate in Human Myometrium. In REPRODUCTIVE SCIENCES Vol. 21 (pp. 130A-131A). Retrieved from https://www.webofscience.com/
Oxytocin: Its Mechanism of Action and Receptor Signalling in the Myometrium
Arrowsmith, S., & Wray, S. (2014). Oxytocin: Its Mechanism of Action and Receptor Signalling in the Myometrium. JOURNAL OF NEUROENDOCRINOLOGY, 26(6), 356-369. doi:10.1111/jne.12154
2013
Oxytocic plant cyclotides as templates for peptide G protein-coupled receptor ligand design
Koehbach, J., O'Brien, M., Muttenthaler, M., Miazzo, M., Akcan, M., Elliott, A. G., . . . Gruber, C. W. (2013). Oxytocic plant cyclotides as templates for peptide G protein-coupled receptor ligand design. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 110(52), 21183-21188. doi:10.1073/pnas.1311183110
A Comparison of the Contractile Properties of Myometrium from Singleton and Twin Pregnancies
Turton, P., Arrowsmith, S., Prescott, J., Ballard, C., Bricker, L., Neilson, J., & Wray, S. (2013). A Comparison of the Contractile Properties of Myometrium from Singleton and Twin Pregnancies. PLOS ONE, 8(5). doi:10.1371/journal.pone.0063800
Evidence of Hypoxic Preconditioning in Late-Pregnant Rat and Laboring Human Uterus
Alotaibi, M., Arrowsmith, S., & Wray, S. (2013). Evidence of Hypoxic Preconditioning in Late-Pregnant Rat and Laboring Human Uterus. REPRODUCTIVE SCIENCES, 20(S3), 170A-171A. Retrieved from https://www.webofscience.com/
Oxytocic plant cyclotides as templates for GPCR ligand design
Koehbach, J., O'Brien, M., Muttenthaler, M., Miazzo, M., Akcan, M., Elliott, A. G., . . . Gruber, C. (2013). Oxytocic plant cyclotides as templates for GPCR ligand design. Proc Natl Acad Sci U S A, 110(52), 21183-21188.
2012
Uterine Smooth Muscle
Wray, S., & Arrowsmith, S. (2012). Uterine Smooth Muscle. In Muscle (pp. 1207-1216). Elsevier. doi:10.1016/b978-0-12-381510-1.00090-9
What do we know about what happens to myometrial function as women age?
Arrowsmith, S., Robinson, H., Noble, K., & Wray, S. (2012). What do we know about what happens to myometrial function as women age?. JOURNAL OF MUSCLE RESEARCH AND CELL MOTILITY, 33(3-4), 209-217. doi:10.1007/s10974-012-9300-2
(2012); Poor Spontaneous and Oxytocin-Stimulated Contractility in Human Myometrium from Postdates Pregnancies.
Arrowsmith, S., Quenby, S., Weeks, A., Burdyga, T., & Wray, S. (2012). (2012); Poor Spontaneous and Oxytocin-Stimulated Contractility in Human Myometrium from Postdates Pregnancies.. PLoS One, 7(5):.
An investigation of the effects of progesterone on contractility in twin vs. singleton pregnancies
Prescott, J., Ballard, C., Arrowsmith, S., Neilson, J., Bricker, L., & Wray, S. (2012). An investigation of the effects of progesterone on contractility in twin vs. singleton pregnancies. In Reprod Sci Vol. Vol 18 (pp. 134A).
Poor spontaneous and oxytocin-stimulated contractility in human myometrium from postdates pregnancies
Arrowsmith, S., Quenby, S., Weeks, A., Burdyga, T., & Wray, S. (2012). Poor spontaneous and oxytocin-stimulated contractility in human myometrium from postdates pregnancies. PLoS One, 7(5).
What do we know about what happens to myometrial function as women age?
Arrowsmith, S., Robinson, H., Noble, K., Turton, P., & Wray, S. (2012). What do we know about what happens to myometrial function as women age?. Journal of Muscle Research and Cell Motility.
2011
Maternal obesity and labour complications following induction of labour in prolonged pregnancy
Arrowsmith, S., Wray, S., & Quenby, S. (2011). Maternal obesity and labour complications following induction of labour in prolonged pregnancy. BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY, 118(5), 578-588. doi:10.1111/j.1471-0528.2010.02889.x
Maternal obesity and labour complications following induction of labour in prolonged pregnancy
Arrowsmith, S., Wray, S., & Quenby, S. (2011). Maternal obesity and labour complications following induction of labour in prolonged pregnancy. British Journal of Obstetrics and Gynaecology, 118(5), 578-588. doi:10.1111/j.1471-0528.2010.02889
Smooth Muscle:Uterine Smooth Muscle
Wray, S., & Arrowsmith, S. (2011). Smooth Muscle:Uterine Smooth Muscle. In J. Hill, & E. Olson (Eds.), Muscle: Fundamental Biology and Mechanisms of Disease (pp. not known). San Diego: Elsevier.
2010
Drugs acting on the pregnant uterus.
Arrowsmith, S., Kendrick, A., & Wray, S. (2010). Drugs acting on the pregnant uterus.. Obstetrics, gynaecology and reproductive medicine, 20(8), 241-247. doi:10.1016/j.ogrm.2010.05.001
'Investigating the aetiology and physiology of postdates pregnancy'
Arrowsmith, S. J. (2010). 'Investigating the aetiology and physiology of postdates pregnancy'. (PhD Thesis, The University of Liverpool).
High myometrial cell membrane cholesterol and poor myometrial function: Cause of prolonged gestation?
Arrowsmith, S., Noble, K., Quenby, S., & Wray, S. (2010). High myometrial cell membrane cholesterol and poor myometrial function: Cause of prolonged gestation?. In Reprod Sci Vol. Vol 17 (pp. 78A).
2009
High myometrial cholesterol impairs uterine contractility
Noble, K., Arrowsmith, S., Turton, P. A., Quenby, S., & Wray, S. (2009). High myometrial cholesterol impairs uterine contractility. In Reprod Sci Vol. Vol 16 (pp. 296A).
Myometrium from postdates pregnancy shows reduced spontaneous contractility in vitro
Arrowsmith, S., Quenby, S., & Wray, S. (2009). Myometrium from postdates pregnancy shows reduced spontaneous contractility in vitro. In Arch.Dis.Child. Fetal Neonatal Ed Vol. 94 (pp. Fa40; PL.04).
Prolonged pregnancy was associated with reduced myometrial contractility and dyslipidaemia
Arrowsmith, S., Wood, L., Noble, K., Wray, S., & Quenby, S. (2009). Prolonged pregnancy was associated with reduced myometrial contractility and dyslipidaemia. In Reprod Sci Vol. Vol 16 (pp. 288A).
The effect of increasing uterine stretch and progesterone on contractile properties of myometrium in multiple pregnancy
Turton, P. A., Arrowsmith, S., Quenby, S., Neilson, J., & Wray, S. (2009). The effect of increasing uterine stretch and progesterone on contractile properties of myometrium in multiple pregnancy. In Arch. Dis. Child. Fetal Neonatal Ed. Vol. 94 (pp. Fa40; PL.03).
The effect of maternal age on myometrial contractility in vitro
Arrowsmith, S., Noble, K., Quenby, S., & Wray, S. (2009). The effect of maternal age on myometrial contractility in vitro. In Reprod Sci Vol. Vol 16 (pp. 289A).