Publications
Selected publications
- Characterising proteolysis during SARS-CoV-2 infection identifies viral cleavage sites and cellular targets with therapeutic potential (Journal article - 2021)
- Multiplexed single-cell proteomics using SCoPE2. (Journal article - 2021)
- Single-cell proteomic and transcriptomic analysis of macrophage heterogeneity using SCoPE2 (Journal article - 2021)
- Polyprotein processing and intermolecular interactions within the viral replication complex spatially and temporally control norovirus protease activity (Journal article - 2019)
- Initial recommendations for performing, benchmarking and reporting single-cell proteomics experiments (Journal article - 2023)
- Prioritized mass spectrometry increases the depth, sensitivity and data completeness of single-cell proteomics (Journal article - 2023)
- Prioritized single-cell proteomics reveals molecular and functional polarization across primary macrophages (Preprint - 2022)
2025
Emergence of SARS-CoV-2 subgenomic RNAs that enhance viral fitness and immune evasion.
Mears, H. V., Young, G. R., Sanderson, T., Harvey, R., Barrett-Rodger, J., Penn, R., . . . Bauer, D. L. V. (2025). Emergence of SARS-CoV-2 subgenomic RNAs that enhance viral fitness and immune evasion.. PLoS biology, 23(1), e3002982. doi:10.1371/journal.pbio.3002982
2024
Development and translation of a method of clinical utility for LC-MS/MS analysis to detect SARS-CoV-2 antigens from ONP swabs and saliva
WS13.04 Multimodal analysis of systemic inflammatory response to elexacaftor/tezacaftor/ivacaftor therapy
Lord, R., Maher, R., Aleem, S., Brice, D., Driver, K., Cytlak-Chaudhuri, U., . . . Jones, A. (2024). WS13.04 Multimodal analysis of systemic inflammatory response to elexacaftor/tezacaftor/ivacaftor therapy. Journal of Cystic Fibrosis, 23, S24-S25. doi:10.1016/s1569-1993(24)00184-x
Filamin B restricts vaccinia virus spread and is targeted by vaccinia virus protein C4.
Georgana, I., Scutts, S. R., Gao, C., Lu, Y., Torres, A. A., Ren, H., . . . Smith, G. L. (2024). Filamin B restricts vaccinia virus spread and is targeted by vaccinia virus protein C4.. Journal of virology, 98(3), e0148523. doi:10.1128/jvi.01485-23
Influence of highly effective modulator therapy on the sputum proteome in cystic fibrosis.
Maher, R. E., Barry, P. J., Emmott, E., Jones, A. M., Lin, L., McNamara, P. S., . . . Lord, R. W. (2024). Influence of highly effective modulator therapy on the sputum proteome in cystic fibrosis.. Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society, 23(2), 269-277. doi:10.1016/j.jcf.2023.10.019
Porcine Sapovirus Protease Controls the Innate Immune Response and Targets TBK1.
Georgana, I., Hosmillo, M., Jahun, A. S., Emmott, E., Sorgeloos, F., Cho, K. -O., & Goodfellow, I. G. (2024). Porcine Sapovirus Protease Controls the Innate Immune Response and Targets TBK1.. Viruses, 16(2), 247. doi:10.3390/v16020247
2023
The SARS-CoV-2 protein ORF3c is a mitochondrial modulator of innate immunity.
Stewart, H., Lu, Y., O'Keefe, S., Valpadashi, A., Cruz-Zaragoza, L. D., Michel, H. A., . . . Firth, A. E. (2023). The SARS-CoV-2 protein ORF3c is a mitochondrial modulator of innate immunity.. iScience, 26(11), 108080. doi:10.1016/j.isci.2023.108080
WS18.03 The effect of CFTR modulator therapy on the sputum proteome in cystic fibrosis
Maher, R., Barry, P., Emmott, E., Jones, A., McNamara, P., Smith, J., & Lord, R. (2023). WS18.03 The effect of CFTR modulator therapy on the sputum proteome in cystic fibrosis. Journal of Cystic Fibrosis, 22, S34. doi:10.1016/s1569-1993(23)00285-0
Prioritized mass spectrometry increases the depth, sensitivity and data completeness of single-cell proteomics
Huffman, R. G., Leduc, A., Wichmann, C., Di Gioia, M., Borriello, F., Specht, H., . . . Slavov, N. (2023). Prioritized mass spectrometry increases the depth, sensitivity and data completeness of single-cell proteomics. NATURE METHODS. doi:10.1038/s41592-023-01830-1
Initial recommendations for performing, benchmarking and reporting single-cell proteomics experiments
Gatto, L., Aebersold, R., Cox, J., Demichev, V., Derks, J., Emmott, E., . . . Slavov, N. (2023). Initial recommendations for performing, benchmarking and reporting single-cell proteomics experiments. NATURE METHODS, 20(3), 375-386. doi:10.1038/s41592-023-01785-3
2022
The SARS-CoV-2 protein ORF3c is a mitochondrial modulator of innate immunity
S26 Untargeted sputum proteomics reveals anti-inflammatory effects of CFTR modulation
Maher, R. E., Barrett, E., Barry, P. J., Emmott, E., Jones, A. M., McNamara, P. S., . . . Lord, R. W. (2022). S26 Untargeted sputum proteomics reveals anti-inflammatory effects of CFTR modulation. In ‘Transformers’ – Transformational treatments and technologies in CF (pp. A20.1-A20). BMJ Publishing Group Ltd and British Thoracic Society. doi:10.1136/thorax-2022-btsabstracts.32
Electrospray ionization: “We taught elephants to fly”
Maher, R., & Emmott, E. (2022). Electrospray ionization: “We taught elephants to fly”. The Biochemist, 44(5), 5-8. doi:10.1042/bio_2022_127
Initial recommendations for performing, benchmarking, and reporting single-cell proteomics experiments
Lagovirus Non-structural Protein p23: A Putative Viroporin That Interacts With Heat Shock Proteins and Uses a Disulfide Bond for Dimerization.
Smertina, E., Carroll, A. J., Boileau, J., Emmott, E., Jenckel, M., Vohra, H., . . . Frese, M. (2022). Lagovirus Non-structural Protein p23: A Putative Viroporin That Interacts With Heat Shock Proteins and Uses a Disulfide Bond for Dimerization.. Frontiers in microbiology, 13, 923256. doi:10.3389/fmicb.2022.923256
Emergence of new subgenomic mRNAs in SARS-CoV-2
Prioritized single-cell proteomics reveals molecular and functional polarization across primary macrophages
2021
Multiplexed single-cell proteomics using SCoPE2.
Petelski, A. A., Emmott, E., Leduc, A., Huffman, R. G., Specht, H., Perlman, D. H., & Slavov, N. (2021). Multiplexed single-cell proteomics using SCoPE2.. Nature protocols, 16(12), 5398-5425. doi:10.1038/s41596-021-00616-z
Characterising proteolysis during SARS-CoV-2 infection identifies viral cleavage sites and cellular targets with therapeutic potential
Meyer, B., Chiaravalli, J., Gellenoncourt, S., Brownridge, P., Bryne, D. P., Daly, L. A., . . . Emmott, E. (2021). Characterising proteolysis during SARS-CoV-2 infection identifies viral cleavage sites and cellular targets with therapeutic potential. NATURE COMMUNICATIONS, 12(1). doi:10.1038/s41467-021-25796-w
Construction of a la carte QconCAT protein standards for multiplexed quantification of user-specified target proteins
Johnson, J., Harman, V. M., Franco, C., Emmott, E., Rockliffe, N., Sun, Y., . . . Beynon, R. J. (2021). Construction of a la carte QconCAT protein standards for multiplexed quantification of user-specified target proteins. BMC BIOLOGY, 19(1). doi:10.1186/s12915-021-01135-9
The Cryo-EM Structure of Vesivirus 2117 Highlights Functional Variations in Entry Pathways for Viruses in Different Clades of the Vesivirus Genus
Sutherland, H., Conley, M. J., Emmott, E., Streetley, J., Goodfellow, I. G., & Bhella, D. (2021). The Cryo-EM Structure of Vesivirus 2117 Highlights Functional Variations in Entry Pathways for Viruses in Different Clades of the Vesivirus Genus. JOURNAL OF VIROLOGY, 95(13). doi:10.1128/JVI.00282-21
Multiplexed single-cell proteomics using SCoPE2
Petelski, A., Emmott, E., Leduc, A., Huffman, G., Specht, H., Perlman, D., & Slavov, N. (2021). Multiplexed single-cell proteomics using SCoPE2. doi:10.1101/2021.03.12.435034
The cryo-EM structure of vesivirus 2117 highlights functional variations in entry pathways for viruses in different clades of the Vesivirus genus
Sutherland, H., Conley, M., Emmott, E., Streetley, J., Goodfellow, I., & Bhella, D. (2021). The cryo-EM structure of vesivirus 2117 highlights functional variations in entry pathways for viruses in different clades of the Vesivirus genus. doi:10.1101/2021.02.05.429895
Single-cell proteomic and transcriptomic analysis of macrophage heterogeneity using SCoPE2
Specht, H., Emmott, E., Petelski, A. A., Huffman, R. G., Perlman, D. H., Serra, M., . . . Slavov, N. (2021). Single-cell proteomic and transcriptomic analysis of macrophage heterogeneity using SCoPE2. GENOME BIOLOGY, 22(1). doi:10.1186/s13059-021-02267-5
2020
Temporal Proteomic Analysis of Herpes Simplex Virus 1 Infection Reveals Cell-Surface Remodeling via pUL56-Mediated GOPC Degradation
Soh, T. K., Davies, C. T. R., Muenzner, J., Hunter, L. M., Barrow, H. G., Connor, V., . . . Crump, C. M. (2020). Temporal Proteomic Analysis of Herpes Simplex Virus 1 Infection Reveals Cell-Surface Remodeling via pUL56-Mediated GOPC Degradation. CELL REPORTS, 33(1). doi:10.1016/j.celrep.2020.108235
The COVID-19 MS Coalition—accelerating diagnostics, prognostics, and treatment
Struwe, W., Emmott, E., Bailey, M., Sharon, M., Sinz, A., Corrales, F. J., . . . Barran, P. (2020). The COVID-19 MS Coalition—accelerating diagnostics, prognostics, and treatment. The Lancet, 395(10239), 1761-1762. doi:10.1016/s0140-6736(20)31211-3
2019
Noroviruses subvert the core stress granule component G3BP1 to promote viral VPg-dependent translation
Hosmillo, M., Lu, J., McAllaster, M. R., Eaglesham, J. B., Wang, X., Emmott, E., . . . Goodfellow, I. G. (2019). Noroviruses subvert the core stress granule component G3BP1 to promote viral VPg-dependent translation. ELIFE, 8. doi:10.7554/eLife.46681
Herpes simplex virus-1 pUL56 degrades GOPC to alter the plasma membrane proteome
Single-cell proteomic and transcriptomic analysis of macrophage heterogeneity
Specht, H., Emmott, E., Petelski, A., Huffman, G., Perlman, D., Serra, M., . . . Slavov, N. (2019). Single-cell proteomic and transcriptomic analysis of macrophage heterogeneity. doi:10.1101/665307
Approaches for Studying Ribosome Specialization.
Emmott, E., Jovanovic, M., & Slavov, N. (2019). Approaches for Studying Ribosome Specialization.. Trends in biochemical sciences, 44(5), 478-479. doi:10.1016/j.tibs.2019.01.008
Ifit1 regulates norovirus infection and enhances the interferon response in murine macrophage-like cells
Polyprotein processing and intermolecular interactions within the viral replication complex spatially and temporally control norovirus protease activity
Emmott, E., de Rougemont, A., Hosmillo, M., Lu, J., Fitzmaurice, T., Haas, J., & Goodfellow, I. (2019). Polyprotein processing and intermolecular interactions within the viral replication complex spatially and temporally control norovirus protease activity. JOURNAL OF BIOLOGICAL CHEMISTRY, 294(11), 4259-4271. doi:10.1074/jbc.RA118.006780
Noroviruses subvert the core stress granule component G3BP1 to promote viral VPg-dependent translation
Hosmillo, M., Lu, J., McAllaster, M., Eaglesham, J., Wang, X., Emmott, E., . . . Goodfellow, I. (2019). Noroviruses subvert the core stress granule component G3BP1 to promote viral VPg-dependent translation. doi:10.1101/571455
On the value of preprints: An early career researcher perspective
Sarabipour, S., Debat, H. J., Emmott, E., Burgess, S. J., Schwessinger, B., & Hensel, Z. (2019). On the value of preprints: An early career researcher perspective. PLOS BIOLOGY, 17(2). doi:10.1371/journal.pbio.3000151
Ribosome Stoichiometry: From Form to Function
Emmott, E., Jovanovic, M., & Slavov, N. (2019). Ribosome Stoichiometry: From Form to Function. TRENDS IN BIOCHEMICAL SCIENCES, 44(2), 95-109. doi:10.1016/j.tibs.2018.10.009
Ifit1 regulates norovirus infection and enhances the interferon response in murine macrophage-like cells
Mears, H., Emmott, E., Chaudhry, Y., Hosmillo, M., Goodfellow, I., & Sweeney, T. (2019). Ifit1 regulates norovirus infection and enhances the interferon response in murine macrophage-like cells. doi:10.12688/wellcomeopenres.15223.1
Ifit1 regulates norovirus infection and enhances the interferon response in murine macrophage-like cells.
Mears, H. V., Emmott, E., Chaudhry, Y., Hosmillo, M., Goodfellow, I. G., & Sweeney, T. R. (2019). Ifit1 regulates norovirus infection and enhances the interferon response in murine macrophage-like cells.. Wellcome open research, 4, 82. doi:10.12688/wellcomeopenres.15223.1
2018
On the value of preprints: an early career researcher perspective
Sarabipour, S., Debat, H., Emmott, E., Burgess, S., Schwessinger, B., & Hensel, Z. (2018). On the value of preprints: an early career researcher perspective. doi:10.7287/peerj.preprints.27400v1
On the value of preprints: an early career researcher perspective
Sarabipour, S., Debat, H. J., Emmott, E., Burgess, S., Schwessinger, B., & Hensel, Z. (2018). On the value of preprints: an early career researcher perspective. doi:10.7287/peerj.preprints.27400
Ribosome stoichiometry: from form to function.
Emmott, E. P., Jovanovic, M., & Slavov, N. (2018). Ribosome stoichiometry: from form to function.. Trends in Biochemical Sciences. doi:10.1016/j.tibs.2018.10.009
UK circulating strains of human parainfluenza 3: an amplicon based next generation sequencing method and phylogenetic analysis
Smielewska, A., Emmott, E., Ranellou, K., Popay, A., Goodfellow, I., & Jalal, H. (2018). UK circulating strains of human parainfluenza 3: an amplicon based next generation sequencing method and phylogenetic analysis. Wellcome Open Research, 3, 118. doi:10.12688/wellcomeopenres.14730.1
Automated sample preparation for high-throughput single-cell proteomics
Specht, H., Harmange, G., Perlman, D., Emmott, E., Niziolek, Z., Budnik, B., & Slavov, N. (2018). Automated sample preparation for high-throughput single-cell proteomics. doi:10.1101/399774
Maintaining confidence in the reporting of scientific outputs
Sarabipour, S., Wissink, E., Burgess, S., Hensel, Z., Debat, H., Emmott, E., . . . Schwessinger, B. (2018). Maintaining confidence in the reporting of scientific outputs. doi:10.7287/peerj.preprints.27098v1
Maintaining confidence in the reporting of scientific outputs
Sarabipour, S., Wissink, E. M., Burgess, S. J., Hensel, Z., Debat, H., Emmott, E., . . . Schwessinger, B. (2018). Maintaining confidence in the reporting of scientific outputs. doi:10.7287/peerj.preprints.27098
Ribosome stoichiometry: from form to function.
Emmott, E., Jovanovic, M., & Slavov, N. (2018). Ribosome stoichiometry: from form to function.. doi:10.7287/peerj.preprints.26991v1
IFIT3 and IFIT2/3 promote IFIT1-mediated translation inhibition by enhancing binding to non-self RNA.
Fleith, R. C., Mears, H. V., Leong, X. Y., Sanford, T. J., Emmott, E., Graham, S. C., . . . Sweeney, T. R. (2018). IFIT3 and IFIT2/3 promote IFIT1-mediated translation inhibition by enhancing binding to non-self RNA.. Nucleic acids research, 46(10), 5269-5285. doi:10.1093/nar/gky191
In vitro sensitivity of human parainfluenza 3 clinical isolates to ribavirin, favipiravir and zanamivir.
Smielewska, A., Emmott, E., Goodfellow, I., & Jalal, H. (2018). In vitro sensitivity of human parainfluenza 3 clinical isolates to ribavirin, favipiravir and zanamivir.. Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology, 102, 19-26. doi:10.1016/j.jcv.2018.02.009
Selection and Characterization of Rupintrivir-Resistant Norwalk Virus Replicon Cells <i>In Vitro</i>.
Kitano, M., Hosmillo, M., Emmott, E., Lu, J., & Goodfellow, I. (2018). Selection and Characterization of Rupintrivir-Resistant Norwalk Virus Replicon Cells <i>In Vitro</i>.. Antimicrobial agents and chemotherapy, 62(5), e00201-e00218. doi:10.1128/aac.00201-18
IFIT3 and IFIT2/3 promote IFIT1-mediated translation inhibition by enhancing binding to non-self RNA
UK circulating strains of human parainfluenza 3: an amplicon based next generation sequencing method and phylogenetic analysis
Smielewska, A., Emmott, E., Ranellou, K., Popay, A., Goodfellow, I., & Jalal, H. (2018). UK circulating strains of human parainfluenza 3: an amplicon based next generation sequencing method and phylogenetic analysis. doi:10.12688/wellcomeopenres.14730.2
UK circulating strains of human parainfluenza 3: an amplicon based next generation sequencing method and phylogenetic analysis.
Smielewska, A., Emmott, E., Ranellou, K., Popay, A., Goodfellow, I., & Jalal, H. (2018). UK circulating strains of human parainfluenza 3: an amplicon based next generation sequencing method and phylogenetic analysis.. Wellcome open research, 3, 118. doi:10.12688/wellcomeopenres.14730.2
Unrecognised Outbreak: Human parainfluenza virus infections in a pediatric oncology unit. A new diagnostic PCR and virus monitoring system may allow early detection of future outbreaks.
Smielewska, A., Pearson, C., Popay, A., Roddick, I., Reacher, M., Emmott, E., . . . Jalal, H. (2018). Unrecognised Outbreak: Human parainfluenza virus infections in a pediatric oncology unit. A new diagnostic PCR and virus monitoring system may allow early detection of future outbreaks.. Wellcome open research, 3, 119. doi:10.12688/wellcomeopenres.14732.1
2017
Phosphoproteomic Analysis Reveals the Importance of Kinase Regulation During Orbivirus Infection
Mohl, B. -P., Emmott, E., & Roy, P. (2017). Phosphoproteomic Analysis Reveals the Importance of Kinase Regulation During Orbivirus Infection. MOLECULAR & CELLULAR PROTEOMICS, 16(11), 1990-2005. doi:10.1074/mcp.M117.067355
VPS18 recruits VPS41 to the human HOPS complex via a RING-RING interaction
Hunter, M. R., Scourfield, E. J., Emmott, E., & Graham, S. C. (2017). VPS18 recruits VPS41 to the human HOPS complex via a RING-RING interaction. BIOCHEMICAL JOURNAL, 474, 3615-3626. doi:10.1042/BCJ20170588
Spatial and temporal control of norovirus protease activity is determined by polyprotein processing and intermolecular interactions within the viral replication complex
Emmott, E., de Rougemont, A., Haas, J., & Goodfellow, I. (2017). Spatial and temporal control of norovirus protease activity is determined by polyprotein processing and intermolecular interactions within the viral replication complex. doi:10.1101/175463
VPS18 recruits VPS41 to the human HOPS complex via a RING-RING interaction
Hunter, M., Scourfield, E., Emmott, E., & Graham, S. (2017). VPS18 recruits VPS41 to the human HOPS complex via a RING-RING interaction. doi:10.1101/169185
Norovirus-Mediated Modification of the Translational Landscape via Virus and Host-Induced Cleavage of Translation Initiation Factors
Emmott, E., Sorgeloos, F., Caddy, S. L., Vashist, S., Sosnovtsev, S., Lloyd, R., . . . Goodfellow, I. (2017). Norovirus-Mediated Modification of the Translational Landscape via Virus and Host-Induced Cleavage of Translation Initiation Factors. MOLECULAR & CELLULAR PROTEOMICS, 16(4), S215-S229. doi:10.1074/mcp.M116.062448
Vesivirus 2117 capsids more closely resemble sapovirus and lagovirus particles than other known vesivirus structures
Conley, M., Emmott, E., Orton, R., Taylor, D., Carneiro, D. G., Murata, K., . . . Bhella, D. (2017). Vesivirus 2117 capsids more closely resemble sapovirus and lagovirus particles than other known vesivirus structures. JOURNAL OF GENERAL VIROLOGY, 98(1), 68-76. doi:10.1099/jgv.0.000658
2016
Norovirus-mediated modification of the translational landscape via virus and host-induced cleavage of translation initiation factors
Emmott, E., Sorgeloos, F., Caddy, S., Vashist, S., Sosnovtsev, S., Lloyd, R., . . . Goodfellow, I. (2016). Norovirus-mediated modification of the translational landscape via virus and host-induced cleavage of translation initiation factors. doi:10.1101/060772
2015
A Cell-based Fluorescence Resonance Energy Transfer (FRET) Sensor Reveals Inter-and Intragenogroup Variations in Norovirus Protease Activity and Polyprotein Cleavage
Emmott, E., Sweeney, T. R., & Goodfellow, I. (2015). A Cell-based Fluorescence Resonance Energy Transfer (FRET) Sensor Reveals Inter-and Intragenogroup Variations in Norovirus Protease Activity and Polyprotein Cleavage. JOURNAL OF BIOLOGICAL CHEMISTRY, 290(46), 27841-27853. doi:10.1074/jbc.M115.688234
Evidence for Human Norovirus Infection of Dogs in the United Kingdom
Caddy, S. L., de Rougemont, A., Emmott, E., El-Attar, L., Mitchell, J. A., Hollinshead, M., . . . Goodfellow, I. (2015). Evidence for Human Norovirus Infection of Dogs in the United Kingdom. JOURNAL OF CLINICAL MICROBIOLOGY, 53(6), 1873-1883. doi:10.1128/JCM.02778-14
Murine Norovirus 1 (MNV1) Replication Induces Translational Control of the Host by Regulating eIF4E Activity during Infection
Royall, E., Doyle, N., Abdul-Wahab, A., Emmott, E., Morley, S. J., Goodfellow, I., . . . Locker, N. (2015). Murine Norovirus 1 (MNV1) Replication Induces Translational Control of the Host by Regulating eIF4E Activity during Infection. JOURNAL OF BIOLOGICAL CHEMISTRY, 290(8), 4748-4758. doi:10.1074/jbc.M114.602649
2014
Norovirus Translation Requires an Interaction between the C Terminus of the Genome-linked Viral Protein VPg and Eukaryotic Translation Initiation Factor 4G
Chung, L., Bailey, D., Leen, E. N., Emmott, E. P., Chaudhry, Y., Roberts, L. O., . . . Goodfellow, I. G. (2014). Norovirus Translation Requires an Interaction between the C Terminus of the Genome-linked Viral Protein VPg and Eukaryotic Translation Initiation Factor 4G. Journal of Biological Chemistry, 289(31), 21738-21750. doi:10.1074/jbc.M114.550657
Identification of Protein Interaction Partners in Mammalian Cells Using SILAC-immunoprecipitation Quantitative Proteomics
Emmott, E., & Goodfellow, L. (2014). Identification of Protein Interaction Partners in Mammalian Cells Using SILAC-immunoprecipitation Quantitative Proteomics. JOVE-JOURNAL OF VISUALIZED EXPERIMENTS, (89). doi:10.3791/51656
Identification of Protein Interaction Partners in Mammalian Cells Using SILAC-immunoprecipitation Quantitative Proteomics
Emmott, E., & Goodfellow, I. (2014). Identification of Protein Interaction Partners in Mammalian Cells Using SILAC-immunoprecipitation Quantitative Proteomics. Journal of Visualized Experiments, (89). doi:10.3791/51656-v
Murine norovirus: propagation, quantification, and genetic manipulation.
Hwang, S., Alhatlani, B., Arias, A., Caddy, S. L., Christodoulou, C., Cunha, J. B., . . . Wobus, C. E. (2014). Murine norovirus: propagation, quantification, and genetic manipulation.. Current protocols in microbiology, 33, 15K.2.1-15K.261. doi:10.1002/9780471729259.mc15k02s33
2013
Progress towards the prevention and treatment of norovirus infections
Arias, A., Emmott, E., Vashist, S., & Goodfellow, I. (2013). Progress towards the prevention and treatment of norovirus infections. FUTURE MICROBIOLOGY, 8(11), 1475-1487. doi:10.2217/fmb.13.109
The Cellular Interactome of the Coronavirus Infectious Bronchitis Virus Nucleocapsid Protein and Functional Implications for Virus Biology
Emmott, E., Munday, D., Bickerton, E., Britton, P., Rodgers, M. A., Whitehouse, A., . . . Hiscox, J. A. (2013). The Cellular Interactome of the Coronavirus Infectious Bronchitis Virus Nucleocapsid Protein and Functional Implications for Virus Biology. JOURNAL OF VIROLOGY, 87(17), 9486-9500. doi:10.1128/JVI.00321-13
Serological Evidence for Multiple Strains of Canine Norovirus in the UK Dog Population
Caddy, S., Emmott, E., El-Attar, L., Mitchell, J., de Rougemont, A., Brownlie, J., & Goodfellow, I. (2013). Serological Evidence for Multiple Strains of Canine Norovirus in the UK Dog Population. PLOS ONE, 8(12). doi:10.1371/journal.pone.0081596
2012
Using SILAC and quantitative proteomics to investigate the interactions between viral and host proteomes
Munday, D. C., Surtees, R., Emmott, E., Dove, B. K., Digard, P., Barr, J. N., . . . Hiscox, J. A. (2012). Using SILAC and quantitative proteomics to investigate the interactions between viral and host proteomes. PROTEOMICS, 12(4-5), 666-672. doi:10.1002/pmic.201100488
2011
Viruses and the Nucleolus
Matthews, D., Emmott, E., & Hiscox, J. (2011). Viruses and the Nucleolus. NUCLEOLUS, 15, 321-345. doi:10.1007/978-1-4614-0514-6_14
2010
Quantitative Proteomic Analysis of A549 Cells Infected with Human Respiratory Syncytial Virus
Munday, D. C., Emmott, E., Surtees, R., Lardeau, C. -H., Wu, W., Duprex, W. P., . . . Hiscox, J. A. (2010). Quantitative Proteomic Analysis of A549 Cells Infected with Human Respiratory Syncytial Virus. MOLECULAR & CELLULAR PROTEOMICS, 9(11), 2438-2459. doi:10.1074/mcp.M110.001859
Elucidation of the avian nucleolar proteome by quantitative proteomics using SILAC and changes in cells infected with the coronavirus infectious bronchitis virus
Emmott, E., Smith, C., Emmett, S. R., Dove, B. K., & Hiscox, J. A. (2010). Elucidation of the avian nucleolar proteome by quantitative proteomics using SILAC and changes in cells infected with the coronavirus infectious bronchitis virus. PROTEOMICS, 10(19), 3558-3562. doi:10.1002/pmic.201000139
Quantitative Proteomics Using SILAC Coupled to LC-MS/MS Reveals Changes in the Nucleolar Proteome in Influenza A Virus-Infected Cells
Emmott, E., Wise, H., Loucaides, E. M., Matthews, D. A., Digard, P., & Hiscox, J. A. (2010). Quantitative Proteomics Using SILAC Coupled to LC-MS/MS Reveals Changes in the Nucleolar Proteome in Influenza A Virus-Infected Cells. JOURNAL OF PROTEOME RESEARCH, 9(10), 5335-5345. doi:10.1021/pr100593g
Quantitative Proteomics Using Stable Isotope Labeling with Amino Acids in Cell Culture Reveals Changes in the Cytoplasmic, Nuclear, and Nucleolar Proteomes in Vero Cells Infected with the Coronavirus Infectious Bronchitis Virus
Emmott, E., Rodgers, M. A., Macdonald, A., McCrory, S., Ajuh, P., & Hiscox, J. A. (2010). Quantitative Proteomics Using Stable Isotope Labeling with Amino Acids in Cell Culture Reveals Changes in the Cytoplasmic, Nuclear, and Nucleolar Proteomes in Vero Cells Infected with the Coronavirus Infectious Bronchitis Virus. MOLECULAR & CELLULAR PROTEOMICS, 9(9), 1920-1936. doi:10.1074/mcp.M900345-MCP200
2009
Nucleolar targeting: the hub of the matter
Emmott, E., & Hiscox, J. A. (2009). Nucleolar targeting: the hub of the matter. EMBO REPORTS, 10(3), 231-238. doi:10.1038/embor.2009.14
Adenovirus type 5 E4 Orf3 protein targets promyelocytic leukaemia (PML) protein nuclear domains for disruption via a sequence in PML isoform II that is predicted as a protein interaction site by bioinformatic analysis
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