Publications
2018
The deubiquitylase USP15 regulates topoisomerase II alpha to maintain genome integrity
Fielding, A. B., Concannon, M., Darling, S., Rusilowicz, E., Sacco, J., Prior, I. A., . . . Coulson, J. M. (2018). The deubiquitylase USP15 regulates topoisomerase II alpha to maintain genome integrity. Oncogene, 37(17), 2326-2342. doi:10.1038/s41388-017-0092-0
2017
Regulation of the cell cycle and centrosome biology by deubiquitylases
Darling, S., Fielding, A. B., Sabat-Pospiech, D., Prior, I. A., & Coulson, J. M. (2017). Regulation of the cell cycle and centrosome biology by deubiquitylases. BIOCHEMICAL SOCIETY TRANSACTIONS, 45, 1125-1136. doi:10.1042/BST20170087
2014
Isolating HeLa cell fractions enriched for clathrin-coated vesicles.
Borner, G. H. H., & Fielding, A. B. (2014). Isolating HeLa cell fractions enriched for clathrin-coated vesicles.. Cold Spring Harbor protocols, 2014(11), 1184-1187. doi:10.1101/pdb.prot083147
Isolation of clathrin-coated vesicles from tissue culture cells.
Borner, G. H. H., & Fielding, A. B. (2014). Isolation of clathrin-coated vesicles from tissue culture cells.. Cold Spring Harbor protocols, 2014(11), 1136-1138. doi:10.1101/pdb.top074435
Using in-gel digestion and an Orbitrap mass spectrometer to analyze the proteome of clathrin-coated vesicles.
Borner, G. H. H., & Fielding, A. B. (2014). Using in-gel digestion and an Orbitrap mass spectrometer to analyze the proteome of clathrin-coated vesicles.. Cold Spring Harbor protocols, 2014(11), 1188-1191. doi:10.1101/pdb.prot083154
Using in-solution digestion, peptide fractionation, and a Q exactive mass spectrometer to analyze the proteome of clathrin-coated vesicles.
Borner, G. H. H., & Fielding, A. B. (2014). Using in-solution digestion, peptide fractionation, and a Q exactive mass spectrometer to analyze the proteome of clathrin-coated vesicles.. Cold Spring Harbor protocols, 2014(11), 1192-1195. doi:10.1101/pdb.prot084137
Abstract
Abstract (n.d.). doi:10.7554/elife.00829.001
2013
Identification of novel small molecule inhibitors of centrosome clustering in cancer cells.
Kawamura, E., Fielding, A. B., Kannan, N., Balgi, A., Eaves, C. J., Roberge, M., & Dedhar, S. (2013). Identification of novel small molecule inhibitors of centrosome clustering in cancer cells.. Oncotarget, 4(10), 1763-1776. doi:10.18632/oncotarget.1198
Mitotic inhibition of clathrin-mediated endocytosis.
Fielding, A. B., & Royle, S. J. (2013). Mitotic inhibition of clathrin-mediated endocytosis.. Cellular and molecular life sciences : CMLS, 70(18), 3423-3433. doi:10.1007/s00018-012-1250-8
Integrin-linked kinase regulates interphase and mitotic microtubule dynamics.
Lim, S., Kawamura, E., Fielding, A. B., Maydan, M., & Dedhar, S. (2013). Integrin-linked kinase regulates interphase and mitotic microtubule dynamics.. PloS one, 8(1), e53702. doi:10.1371/journal.pone.0053702
2012
Endocytosis is inhibited during mitosis
Fielding, A. B., Willox, A. K., Okeke, E., & Royle, S. J. (2012). Endocytosis is inhibited during mitosis. Proc. Natl. Acad. Sci. U. S. A., 109, 6572-6577.
2011
A critical role of integrin-linked kinase, ch-TOG and TACC3 in centrosome clustering in cancer cells.
Fielding, A. B., Lim, S., Montgomery, K., Dobreva, I., & Dedhar, S. (2011). A critical role of integrin-linked kinase, ch-TOG and TACC3 in centrosome clustering in cancer cells.. Oncogene, 30(5), 521-534. doi:10.1038/onc.2010.431
2009
The mitotic functions of integrin-linked kinase.
Fielding, A. B., & Dedhar, S. (2009). The mitotic functions of integrin-linked kinase.. Cancer metastasis reviews, 28(1-2), 99-111. doi:10.1007/s10555-008-9177-0
2008
Integrin-linked kinase--essential roles in physiology and cancer biology.
McDonald, P. C., Fielding, A. B., & Dedhar, S. (2008). Integrin-linked kinase--essential roles in physiology and cancer biology.. Journal of cell science, 121(Pt 19), 3121-3132. doi:10.1242/jcs.017996
Integrin-linked kinase localizes to the centrosome and regulates mitotic spindle organization.
Fielding, A. B., Dobreva, I., McDonald, P. C., Foster, L. J., & Dedhar, S. (2008). Integrin-linked kinase localizes to the centrosome and regulates mitotic spindle organization.. The Journal of cell biology, 180(4), 681-689. doi:10.1083/jcb.200710074
2005
Membrane traffic in cytokinesis
Yu, X., Matheson, J., Fielding, A. B., & Gould, G. W. (2005). Membrane traffic in cytokinesis. Biochemical Society Transactions, 33(6), 1290. doi:10.1042/bst20051290
2003
Arfophilins are dual Arf/Rab 11 binding proteins that regulate recycling endosome distribution and are related to Drosophila nuclear fallout.
Hickson, G. R. X., Matheson, J., Riggs, B., Maier, V. H., Fielding, A. B., Prekeris, R., . . . Gould, G. W. (2003). Arfophilins are dual Arf/Rab 11 binding proteins that regulate recycling endosome distribution and are related to Drosophila nuclear fallout.. Molecular biology of the cell, 14(7), 2908-2920. doi:10.1091/mbc.e03-03-0160