My research focuses on the comparison of treatment in clinical research. This includes statistical methods for causal analysis, efficient clinical trial design and tools for the identification of prognostic/predictive clinical biomarkers.
In particular I have recently been awarded an NIHR advanced fellowship to investigate the uses and applications of Personalised Synthetic Controls. This includes using statistical models to predict how we would expect patients to perform under a standard of care. Comparing patients actual performance against these predictions can then give us insights into what treatments may work best for patients!