Dr Shahram Mesdaghi – Protein bioinformatician
Shah is part of the Professor Daniel Rigden's group in the Institute of Systems, Molecular and Integrative Biology where his research focusses on Protein Bioinformatics. Shah is a specialist in the application of diverse bioinformatics tools to proteins of interest to predict the structure and functions of uncharacterised proteins.
At the CBF he will be using structural bioinformatics to understand medin generation. More specifically, he will use molecular dynamics analysis to assess how medin cleavage sites become accessible. This will include analyses in the presence or absence of lipid bilayer. Additionally, we will use experimental results from collaborators to identify targets to perform protein bioinformatics and characterize candidate genes that affect medin processing e.g., functional annotation and structural modelling.
Kawinnat Sue-ob - Data Scientist
Kawinnat, (aka Pimmy), has joined the CBF as a part-time data scientist alongside her PhD study under supervision of Prof. Andy Jones. She is currently working on SUMOylation (post translational modification), focusing gene identification, evolution and transcriptomic regulation in plants. Pimmy's work at the CBF includes gene identification in model organisms using bioinformatic approaches and website administration and design.
Dr Arturas Grauslys – Senior Bioinformatician at Eliptica
Arturas joined the CBF as a full-time data scientist after a post-doctoral position building software and analytical pipelines for NMR metabolomics. In his time in the CBF he specialised in health data science, applying machine learning approaches to solve complex problems ranging from biomarker discovery to drugs classifications. Arturas is also a developer of our popular R courses. He is now a senior bioinformatician in Eliptica where he is working on personalised medicine and holds an honorary position with us.
Dr Kim Clarke - Associate Principal Informatician at Astra Zeneca
Kim joined the CBF as a full-time data analyst after a post-doctoral position investigating the molecular drivers of metastasis in renal tumours. In his time in the CBF he specialised in applying multi-omics based strategies to issues of human health and diseases and the development of novel approaches to analyse single cell transcriptomics data. Kim is now a senior data scientist in Astra Zeneca and holds an honorary position with us.
Dr Daniel Green – Head of Bioinformatics
Dan worked at the CBF while undertaking a MRC/Versus Arthritis PhD developing statistical and machine learning models for biomarker discovery. Dan is now Head of Bioinformatics at Greywolf Therapeutics and continues a close collaboration with the CBF.
Honorary Professor Francesco Falciani
Francesco is a specialist in developing novel computational approaches in systems biology and the application of these techniques to complex biological systems. Projects in Francesco’s research group have ranged from modelling the effect of pollutants in the environment to cancer and ageing. He was very involved in the Systems Medicine efforts in the MRC Centre for Drug Safety Science and in the area of blood malignancies.
Francesco has recently left the university to focus on his consultancy work but remains a great source of advice and inspiration for our work.
Alumni
- Mr John Heap - Senior Software Engineer and Facility Manager, retired
- Dr Philipp Antczak - University of Cologne
- Mr Simon Perkins - Currently working as Principal Informatician in Astra Zeneca
- Dr Mara Kozic - Bioinformatics analyst in DIOSynVax
- Dr Louise Yukari Takeshita
- Mr John Herbert - Freelance bioinformatician
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