Professor Sylvie Urbe Biochemistry, Cell and Systems Biology +44 (0)151 794 5432 Work email Urbe@liverpool.ac.uk Personal Websitehttp://pcwww.liv.ac.uk/~urbe/ About Research Publications Teaching Professional Activities Teaching Modules for 2023-24 Cell Signalling in Health and Disease Module code: LIFE305 Role: Teaching Essential Skills for the Life Sciences 2 Module code: LIFE223 Role: Teaching MSC RESEARCH PROJECT Module code: LIFE703 Role: Teaching Principles of Molecular Physiology Research Module code: LIFE309 Role: Module Co-ordinator Supervised ThesesCharacterisation of USP31- the 3rd microtubule localising DeubiquitylaseCharacterisation of the Parkinson’s disease related protein LRRK2 in melanoma cells and melanocytesCharacterising the function of the mitochondrial deubiquitylase USP30 in mitophagyIdentification and characterisation of microtubule binding proteinsIdentification of deubiquitinases involved in the regulation of the immune checkpoint protein PD-L1Identification of deubiquitinases involved in the regulation of the immune checkpoint protein PD-L1Identification of deubiquitinases involved in the regulation of the immune checkpoint protein PD-L1Identification of deubiquitinases involved in the regulation of the immune checkpoint protein PD-L1Interlinking functions of the TOM complex in mitophagy and mitochondrial importInvestigating the interplay between the Parkinson’s Disease proteins VPS35 and LRRK2 in an isogenic cell model systemMolecular Mechanisms of Pexophagy and Mitophagy: An In-Depth Study in Mammalian Cells and Drosophila ModelsParkinson’s Disease-associated proteins: studying their role in mitophagy with cellular and Drosophila modelsThe role of HRS phosphorylation in endosomal trafficking and signalling.The role of the mitochondrial deubiquitylase USP30 in cellular fitness and death