Photo of Professor Sylvie Urbe

Professor Sylvie Urbe

Biochemistry, Cell and Systems Biology

    Research

    Research Grants

    Wellcome Trust Four Year PhD Studentship with the PhD Programme in Cellular and Molecular Physiology - 2010

    WELLCOME TRUST (UK)

    October 2010 - March 2015

    Towards the clinical positioning of a first selective DUB inhibitor

    NORTH WEST CANCER RESEARCH INCORPORATING CLATTERBRIDGE CANCER RESEARCH (UK)

    October 2018 - December 2021

    European Research Training to Decipher The Ub Code : identification of potential biomarkers and drug targets (Ubicode)

    EUROPEAN COMMISSION

    January 2018 - December 2022

    Fly models for Mitophagy

    FORMA THERAPEUTICS (USA)

    September 2016 - February 2017

    Protein Homeostasis and the Ubiquitination pathway in Parkinson's disease

    CELGENE LTD (USA), FORMA THERAPEUTICS (USA)

    March 2017 - June 2023

    Mitochondrial ubiquitin dynamics and apoptotic cell death

    MEDICAL RESEARCH COUNCIL

    May 2016 - May 2019

    MELANOPARK

    EUROPEAN COMMISSION

    July 2015 - June 2017

    The flipside to Parkin- regulation of mitochondrial deubiquitylase activity

    PARKINSONS DISEASE SOCIETY OF THE UK (UK)

    September 2016 - August 2019

    Wellcome Trust Four-Year PhD Studentship with the Cellular and Molecular Physiology Programme

    WELLCOME TRUST (UK)

    October 2011 - March 2016

    Four year PhD programme in Cellular and Molecular Physiology.

    WELLCOME TRUST (UK)

    October 2005 - September 2009

    Liverpool 3View: a national hub for 3D-EM bioscience research

    BIOTECHNOLOGY & BIOLOGICAL SCIENCE RESEARCH COUNCIL

    January 2014 - December 2014

    miRNA profiling in isogenic cell lines and contingencies on deubiquitinase activity

    CANCER RESEARCH UK (UK)

    April 2012 - March 2013

    Characterisation of the dynamic ESCRT-0 interactome

    NORTH WEST CANCER RESEARCH FUND

    April 2012 - December 2014

    The role of USP-15 in reversible REST ubiquitination in cancer

    NORTH WEST CANCER RESEARCH FUND

    August 2009 - March 2013

    Analysis of cell cycle and signaling pathways by quantitative mass spectroscopy.

    CANCER RESEARCH UK (UK)

    September 2008 - August 2009

    Plasticity of epithelial cell boundaries governed by EGF and actin remodelling.

    BIOTECHNOLOGY & BIOLOGICAL SCIENCE RESEARCH COUNCIL

    November 2014 - October 2017

    Securing and enhancing Liverpool Biomedical EM cryo-preparation facilities

    WELLCOME TRUST (UK)

    July 2007 - June 2010

    Stretching the supply routes: ErbB2 gene amplification and endocytic recycling in metastatic breast cancer

    BREAST CANCER NOW (UK)

    January 2015 - January 2019

    CR-UK Cancer Research Centre - Non Clinical Training Account 2009-2013

    CANCER RESEARCH UK (UK)

    July 2009 - September 2014

    PHD - Studentship - Monika Chojnowska.

    CANCER RESEARCH UK (UK)

    October 2007 - September 2011

    Regulation of growth factor receptor dynamics by reversible ubiquitination.

    CANCER RESEARCH UK (UK)

    April 2006 - July 2013

    AMSH ubiquitin isopeptidase function at the endosome: control of receptor tyrosine kinase down-regulation.

    NORTH WEST CANCER RESEARCH FUND

    January 2006 - January 2008

    Evaluation of DUBs as drug targets for control of HGF-dependent invasive growth

    CANCER RESEARCH UK (UK)

    September 2007 - August 2009

    Characterisation of a centrosome and microtubule associated deubiquitinating enzyme

    WELLCOME TRUST (UK)

    September 2010 - December 2013

    Hrs: A Case Study of an Endocytic Protein at the Interface of Membrane Traffic and Signal Transduction.

    WELLCOME TRUST (UK)

    April 2002 - August 2006

    Regulation and substrate-specificity for isoforms of the debiquitinase USP15 during the cell cycle

    NORTH WEST CANCER RESEARCH FUND

    February 2013 - February 2015