Photo of Prof Sylvie Urbe

Prof Sylvie Urbe

Cellular and Molecular Physiology

    Research

    Research Grants

    Wellcome Trust Four Year PhD Studentship with the PhD Programme in Cellular and Molecular Physiology - 2010

    WELLCOME TRUST (UK)

    October 2010 - March 2015

    Towards the clinical positioning of a first selective DUB inhibitor

    NORTH WEST CANCER RESEARCH INCORPORATING CLATTERBRIDGE CANCER RESEARCH (UK)

    October 2018 - September 2020

    European Research Training to Decipher The Ub Code : identification of potential biomarkers and drug targets (UbiCODE)

    EUROPEAN COMMISSION

    January 2018 - December 2021

    Fly models for Mitophagy

    FORMA THERAPEUTICS (USA)

    September 2016 - February 2017

    Protein Homeostasis and the Ubiquitination pathway in Parkinson's disease

    CELGENE LTD (USA), FORMA THERAPEUTICS (USA)

    March 2017 - December 2021

    Mitochondrial ubiquitin dynamics and apoptotic cell death

    MEDICAL RESEARCH COUNCIL (MRC)

    May 2016 - May 2019

    MELANOPARK

    EUROPEAN COMMISSION

    July 2015 - June 2017

    The flipside to Parkin- regulation of mitochondrial deubiquitylase activity

    PARKINSONS DISEASE SOCIETY OF THE UK (UK)

    September 2016 - August 2019

    Wellcome Trust Four-Year PhD Studentship with the Cellular and Molecular Physiology Programme

    WELLCOME TRUST (UK)

    October 2011 - March 2016

    Four year PhD programme in Cellular and Molecular Physiology.

    WELLCOME TRUST (UK)

    October 2005 - September 2009

    Liverpool 3View: a national hub for 3D-EM bioscience research

    BIOTECHNOLOGY & BIOLOGICAL SCIENCE RESEARCH COUNCIL (BBSRC)

    January 2014 - December 2014

    miRNA profiling in isogenic cell lines and contingencies on deubiquitinase activity

    CANCER RESEARCH UK (UK)

    April 2012 - March 2013

    Characterisation of the dynamic ESCRT-0 interactome

    NORTH WEST CANCER RESEARCH FUND

    April 2012 - December 2014

    The role of USP-15 in reversible REST ubiquitination in cancer

    NORTH WEST CANCER RESEARCH FUND

    August 2009 - March 2013

    Analysis of cell cycle and signaling pathways by quantitative mass spectroscopy.

    CANCER RESEARCH UK (UK)

    September 2008 - August 2009

    Plasticity of epithelial cell boundaries governed by EGF and actin remodelling.

    BIOTECHNOLOGY & BIOLOGICAL SCIENCE RESEARCH COUNCIL (BBSRC)

    November 2014 - October 2017

    Securing and enhancing Liverpool Biomedical EM cryo-preparation facilities

    WELLCOME TRUST (UK)

    July 2007 - June 2010

    Stretching the supply routes: ErbB2 gene amplification and endocytic recycling in metastatic breast cancer

    BREAST CANCER NOW (UK)

    January 2015 - January 2019

    CR-UK Cancer Research Centre - Non Clinical Training Account 2009-2013

    CANCER RESEARCH UK (UK)

    July 2009 - September 2014

    PHD - Studentship - Monika Chojnowska.

    CANCER RESEARCH UK (UK)

    October 2007 - September 2011

    Regulation of growth factor receptor dynamics by reversible ubiquitination.

    CANCER RESEARCH UK (UK)

    April 2006 - July 2013

    AMSH ubiquitin isopeptidase function at the endosome: control of receptor tyrosine kinase down-regulation.

    NORTH WEST CANCER RESEARCH FUND

    January 2006 - January 2008

    Evaluation of DUBs as drug targets for control of HGF-dependent invasive growth

    CANCER RESEARCH UK (UK)

    September 2007 - August 2009

    Characterisation of a centrosome and microtubule associated deubiquitinating enzyme

    WELLCOME TRUST (UK)

    September 2010 - December 2013

    Hrs: A Case Study of an Endocytic Protein at the Interface of Membrane Traffic and Signal Transduction.

    WELLCOME TRUST (UK)

    April 2002 - August 2006

    Regulation and substrate-specificity for isoforms of the debiquitinase USP15 during the cell cycle

    NORTH WEST CANCER RESEARCH FUND

    February 2013 - February 2015