Prof Andrea Varro M.D., PhD

Professor Molecular & Physiology Cell Signalling

    Research

    Research Interest 1

    Role of microenveronment in cancer initiation and progression

    Research Grants

    MRes in Biomedical Sciences, Biology of Cancer Strand

    NORTH WEST CANCER RESEARCH FUND

    January 2009 - December 2012

    Four year PhD programme in Cellular and Molecular Physiology.

    WELLCOME TRUST (UK)

    October 2005 - September 2009

    Gut-Brain Signalling: Roles of Lipid, Cholecystokinin and the Vagus Nerve in Man.

    BIOTECHNOLOGY & BIOLOGICAL SCIENCE RESEARCH COUNCIL (BBSRC)

    October 1999 - October 2002

    The neuroendocrinology of the upper gastrointestinal tract

    MEDICAL RESEARCH COUNCIL (MRC)

    October 1998 - September 2003

    Bridging and accelerating the translation of novel scientific findings for health and wealth gain

    MEDICAL RESEARCH COUNCIL (MRC)

    March 2014 - August 2015

    Identification of patients at risk of gastric cancer

    NORTH WEST CANCER RESEARCH INCORPORATING CLATTERBRIDGE CANCER RESEARCH (UK)

    February 2014 - January 2015

    Quantitative high-throughput proteomics for biomedical research.

    MEDICAL RESEARCH COUNCIL (MRC)

    March 2005 - March 2008

    The endocrinology of the upper gastrointestinal tract.

    MEDICAL RESEARCH COUNCIL (MRC)

    October 2003 - September 2008

    Identification of novel stromal targets for early detection and targeted therapy in pancreatic and oesophageal cancer

    CANCER RESEARCH UK (CRUK) (UK)

    July 2010 - September 2011

    Actions of cholecystokinin on vagal afferent neurons

    WELLCOME TRUST (UK)

    December 2009 - January 2013

    Vacation Scholarship. Characterisation of epithelial mesenchymal interactions in the oesophageus.

    WELLCOME TRUST (UK)

    July 2008 - September 2008

    Regulated and deregulated secretion from primary myofibroblasts in gastric cancer.

    NORTH WEST CANCER RESEARCH FUND

    October 2008 - September 2011

    Myofibroblast control of oesophageal squamous cancer invasion: role of chemerin

    NORTH WEST CANCER RESEARCH FUND, NORTH WEST CANCER RESEARCH INCORPORATING CLATTERBRIDGE CANCER RESEARCH (UK)

    February 2015 - December 2018

    Maintaining functional integrity of gastric epithelium:identification of novel transcriptional mechanisms.

    WELLCOME TRUST (UK)

    March 2010 - June 2013

    Nutrient modulation of vagal afferent signalling.

    BIOTECHNOLOGY & BIOLOGICAL SCIENCE RESEARCH COUNCIL (BBSRC)

    September 2006 - August 2009

    Gut-brain signalling in man: modulation of the cholecystokinin-vagus nerve pathway.

    BIOTECHNOLOGY & BIOLOGICAL SCIENCE RESEARCH COUNCIL (BBSRC)

    May 2003 - September 2006

    Bench fees for Hanan M Garalla

    LIBYAN EMBASSY IN LONDON

    July 2013 - June 2016

    Four-year PhD programme in cellular and molecular physiology.

    WELLCOME TRUST (UK)

    October 2004 - September 2008

    Four year PhD Programme (2008)

    WELLCOME TRUST (UK)

    October 2008 - December 2012

    Importance of alternative pathway NF-κB signalling in Helicobacter-induced gastric carcinogenesis

    NORTH WEST CANCER RESEARCH FUND

    January 2013 - September 2016

    Validation and exploitation of biomarkers for identification of patients at risk of gastric cancer

    NORTH WEST CANCER RESEARCH FUND

    November 2012 - October 2014

    Application of automated, high-content, live-cell, fluorescence imaging in multidisciplinary studies of epithelial, neuronal and stem cell function.

    BIOTECHNOLOGY & BIOLOGICAL SCIENCE RESEARCH COUNCIL (BBSRC)

    April 2007 - March 2008

    Identification of patients at risk of gastric cancer

    ROYAL LIVERPOOL AND BROADGREEN UNIVERSITY HOSPITALS NHS TRUST (UK)

    April 2012 - September 2013

    Four year PhD Programme in Cellular and Molecular Physiology.

    WELLCOME TRUST (UK)

    October 2000 - November 2004

    Four year PhD Programme in Cellular and Molecular Physiology.

    WELLCOME TRUST (UK)

    October 2003 - September 2007

    Developing a collaborative resource for ChIP based analyses of cancer related transcriptional networks

    CANCER RESEARCH UK (CRUK) (UK)

    April 2012 - March 2013

    Towards disease diagnosis through spectrochemical imaging of tissue architecture.

    ENGINEERING & PHYSICAL SCIENCES RESEARCH COUNCIL (EPSRC)

    June 2013 - September 2016

    Capacity building award in integrative mammalian biology

    BIOTECHNOLOGY & BIOLOGICAL SCIENCE RESEARCH COUNCIL (BBSRC)

    January 2007 - October 2015

    Investigation of the importance of the gastrin family of peptides and gastrin/CCKb receptor in inflammatory bowel disease.

    NAT ASSOC FOR COLITIS & CROHNS DISEASE (UK)

    September 2003 - September 2007

    Investigation of the mechanisms by which progastrin promotes colonic carcinogenesis.

    NORTH WEST CANCER RESEARCH FUND

    June 2006 - December 2010

    YEAR 1 (part2) Wellcome Trust ISSF Non-Clinical Fellowships

    WELLCOME TRUST (UK)

    October 2012 - December 2021

    How does the microbiome of the hypochlorhydric stomach promote gastric tumourigenesis?

    WORLDWIDE CANCER RESEARCH (UK)

    November 2012 - October 2015

    The effect of gastrin on gastric tubulogenesis.

    WELLCOME TRUST (UK)

    October 1999 - September 2003

    Wellcome Trust 3 year PhD - cellular and molecular physiology

    WELLCOME TRUST (UK)

    October 2010 - September 2013

    Identification of patients at risk of gastric cancer due to helicobacter pylori infection

    DEPARTMENT OF HEALTH (UK) (NIHR)

    September 2007 - March 2012

    Role of MMP-7 in the pathogenesis of gastric cancer.

    NORTH WEST CANCER RESEARCH FUND

    November 2003 - November 2006

    YEAR 1 Wellcome Trust ISSF Non-Clinical Fellowships

    WELLCOME TRUST (UK)

    October 2011 - May 2018

    Research Collaborations

    Dan Palmer

    Internal

    Dr Peter Hegy

    External: University of Szeged Medical School

    Characterisation of epithelial & mesenchymal transporters in the gastrointestinal (GI) tract.
    Regulation of the stem cell niche in the GI tract.

    Prof Tim Wang

    External: Columbia University Medical & Irving Cancer Research Center , New York

    Regulation of the gastric stem cell niche

    Dr Mark Pritchard

    Internal

    Obtaining clinical samples.

    Profs Dockray, Varro, and Dimaline

    Internal

    Collaboration on role of gastrin in gastrointestinal physiology

    Profs Dockray, Varro and Dimaline

    Internal

    Dockray, Varro, Dimaline and group

    Internal

    Gastrin and apoptosis