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Professor William Hope FRACP, FRCPA, PhD

Dame Sally Davies Chair of AMR Research Pharmacology & Therapeutics

Work email William.Hope@liverpool.ac.uk

Teaching

Pharmacokinetics, pharmacodynamics, pharmacometrics, population pharmacokinetics, mathematical modelling

The Antimicrobial Pharmacodynamics Laboratory invites researchers to spend time in Liverpool, either independently or via ESCMID Collaborative Centre/ Observerships (see https://www.escmid.org/profession_career/collaborative_centres_observerships/ for details). We are happy to help model clinical and experimental datsets , as well as teach laboratory methods such as the hollow fibre infection model.

See Antimicrobial Pharmacodynamics and Therapeutics for more details

Supervised Theses

Ciprofloxacin Therapy for Neonates and Young Infants:A Clinical Pharmacological Perspective including Pharmacokinetics (PK) and Pharmacodynamics (PD)

Determining an Alternate Antimicrobial Regimen for the Empiric Treatment of Neonatal Sepsis in Low- and Middle-Income Countries in the Context of Rising Antimicrobial Resistance

Developing Drugs for Multi-Resistant Gram-Negative Infections in the Era of Antimicrobial Resistance.

In vitro Models to Describe the Pharmacokinetics and Pharmacodynamics of New and Existing Antifungal Agents

Optimization of Antimicrobial Therapy for Gram-positive Bacterial Infections in Children using a Translational Pharmacological Approach

Pharmacokinetics & Pharmacodynamics of New Treatment Options for Infections caused by Multi-Drug Resistant Gram-Negative Pathogens

THE PHARMACOKINETICS AND PHARMACODYNAMICS OF ANTIFUNGAL AGENTS FOR HIV-ASSOCIATED INVASIVE FUNGAL INFECTIONS