2023
2022
Agyeman, A. A., You, T., Chan, P. L. S., Lonsdale, D. O., Hadjichrysanthou, C., Mahungu, T., . . . Standing, J. F. (2022). Comparative assessment of viral dynamic models for SARS-CoV-2 for pharmacodynamic assessment in early treatment trials.. British journal of clinical pharmacology, 88(12), 5428-5433. doi:10.1111/bcp.15518DOI: 10.1111/bcp.15518
UK CTAP Briefing on Ivermectin. (Report)
Bonnet, M., Cave, A., Hofer, M., McConkey, G., Medcalf, N., Smith, S., . . . You, T. (n.d.). UK CTAP Briefing on Ivermectin. (DOI: 10.5281/zenodo.6011345.).
UK CTAP Briefing on Vitamin D. National Core Studies (Report)
Bonnet, M., Cave, A., Hofer, M., McConkey, G., Medcalf, N., Smith, S., . . . You, T. (n.d.). UK CTAP Briefing on Vitamin D. National Core Studies (DOI: 10.5281/zenodo.6011333.).
Choosing drugs for UK COVID-19 treatment trials. (Journal article)
Chinnery, P. F., Bonnet, M., Cave, A., Hofer, M. P., Lamb, A., McConkey, G. A., . . . You, T. (2022). Choosing drugs for UK COVID-19 treatment trials.. Nature reviews. Drug discovery, 21(2), 81-82. doi:10.1038/d41573-021-00203-7DOI: 10.1038/d41573-021-00203-7
2021
Huang, Z., & You, T. (2021). Personalise vitamin D<sub>3</sub> using physiologically based pharmacokinetic modelling.. CPT: pharmacometrics & systems pharmacology, 10(7), 723-734. doi:10.1002/psp4.12640DOI: 10.1002/psp4.12640
2018
A mathematical model of antibody-dependent cellular cytotoxicity (ADCC). (Journal article)
Hoffman, F., Gavaghan, D., Osborne, J., Barrett, I. P., You, T., Ghadially, H., . . . Byrne, H. M. (2018). A mathematical model of antibody-dependent cellular cytotoxicity (ADCC).. Journal of theoretical biology, 436, 39-50. doi:10.1016/j.jtbi.2017.09.031DOI: 10.1016/j.jtbi.2017.09.031
2015
Investigating receptor enzyme activity using time-scale analysis. (Journal article)
You, T., & Yue, H. (2015). Investigating receptor enzyme activity using time-scale analysis.. IET systems biology, 9(6), 268-276. doi:10.1049/iet-syb.2015.0037DOI: 10.1049/iet-syb.2015.0037
2014
Time scale analysis of receptor enzyme activity: Irreversible inhibition sometimes exhibits incubation-time independence (Conference Paper)
You, T., & Yue, H. (2014). Time scale analysis of receptor enzyme activity: Irreversible inhibition sometimes exhibits incubation-time independence. In 2014 IEEE International Conference on Bioinformatics and Biomedicine (BIBM). IEEE. doi:10.1109/bibm.2014.6999257DOI: 10.1109/bibm.2014.6999257
Kaloriti, D., Jacobsen, M., Yin, Z., Patterson, M., Tillmann, A., Smith, D. A., . . . Brown, A. J. P. (2014). Mechanisms underlying the exquisite sensitivity of Candida albicans to combinatorial cationic and oxidative stress that enhances the potent fungicidal activity of phagocytes.. mBio, 5(4), e01334-e01314. doi:10.1128/mbio.01334-14DOI: 10.1128/mbio.01334-14
2013
Eukaryotic translation initiation factor interactions (Chapter)
You, T., Coghill, G., & Brown, A. (2013). Eukaryotic translation initiation factor interactions. In Encyclopedia of Systems Biology. Springer.
Translational control of GCN4 (Chapter)
You, T., Coghill, G., & Brown, A. (2013). Translational control of GCN4. In Encyclopedia of Systems Biology. Springer.
2012
Kaloriti, D., Tillmann, A., Cook, E., Jacobsen, M., You, T., Lenardon, M., . . . Brown, A. J. P. (2012). Combinatorial stresses kill pathogenic Candida species.. Medical mycology, 50(7), 699-709. doi:10.3109/13693786.2012.672770DOI: 10.3109/13693786.2012.672770
You, T., Ingram, P., Jacobsen, M. D., Cook, E., McDonagh, A., Thorne, T., . . . Brown, A. J. P. (2012). A systems biology analysis of long and short-term memories of osmotic stress adaptation in fungi.. BMC research notes, 5, 258. doi:10.1186/1756-0500-5-258DOI: 10.1186/1756-0500-5-258
2011
You, T., Stansfield, I., Romano, M. C., Brown, A. J. P., & Coghill, G. M. (2011). Analysing GCN4 translational control in yeast by stochastic chemical kinetics modelling and simulation.. BMC systems biology, 5, 131. doi:10.1186/1752-0509-5-131DOI: 10.1186/1752-0509-5-131
2010
A quantitative model for mRNA translation in Saccharomyces cerevisiae. (Journal article)
You, T., Coghill, G. M., & Brown, A. J. P. (2010). A quantitative model for mRNA translation in Saccharomyces cerevisiae.. Yeast (Chichester, England), 27(10), 785-800. doi:10.1002/yea.1770DOI: 10.1002/yea.1770
2009
Modelling and Simulation of Amino Acid Starvation Responses in Yeast Saccharomyces cerevisiae (Thesis / Dissertation)
You, T. (2009, May 23). Modelling and Simulation of Amino Acid Starvation Responses in Yeast Saccharomyces cerevisiae.
2006
Proteomic analysis of colorectal cancer reveals alterations in metabolic pathways: mechanism of tumorigenesis. (Journal article)
Bi, X., Lin, Q., Foo, T. W., Joshi, S., You, T., Shen, H. -M., . . . Hew, C. -L. (2006). Proteomic analysis of colorectal cancer reveals alterations in metabolic pathways: mechanism of tumorigenesis.. Molecular & cellular proteomics : MCP, 5(6), 1119-1130. doi:10.1074/mcp.m500432-mcp200DOI: 10.1074/mcp.m500432-mcp200
SPLASH: systematic proteomics laboratory analysis and storage hub. (Journal article)
Lo, S. L., You, T., Lin, Q., Joshi, S. B., Chung, M. C. M., & Hew, C. L. (2006). SPLASH: systematic proteomics laboratory analysis and storage hub.. Proteomics, 6(6), 1758-1769. doi:10.1002/pmic.200500378DOI: 10.1002/pmic.200500378