2022
Agyeman, A. A., You, T., Chan, P. L. S., Lonsdale, D. O., Hadjichrysanthou, C., Mahungu, T., . . . Standing, J. F. (2022). Comparative assessment of viral dynamic models for SARS‐CoV‐2 for pharmacodynamic assessment in early treatment trials. British Journal of Clinical Pharmacology, 88(12), 5428-5433. doi:10.1111/bcp.15518DOI: 10.1111/bcp.15518
UK CTAP Briefing on Ivermectin. (Report)
Bonnet, M., Cave, A., Hofer, M., McConkey, G., Medcalf, N., Smith, S., . . . You, T. (n.d.). UK CTAP Briefing on Ivermectin. (DOI: 10.5281/zenodo.6011345.).
UK CTAP Briefing on Vitamin D. National Core Studies (Report)
Bonnet, M., Cave, A., Hofer, M., McConkey, G., Medcalf, N., Smith, S., . . . You, T. (n.d.). UK CTAP Briefing on Vitamin D. National Core Studies (DOI: 10.5281/zenodo.6011333.).
Choosing drugs for UK COVID-19 treatment trials (Journal article)
Chinnery, P. F., Bonnet, M., Cave, A., Hofer, M. P., Lamb, A., McConkey, G. A., . . . You, T. (2022). Choosing drugs for UK COVID-19 treatment trials. Nature Reviews Drug Discovery, 21(2), 81-82. doi:10.1038/d41573-021-00203-7DOI: 10.1038/d41573-021-00203-7
2021
Personalise vitamin D
<sub>3</sub>
using physiologically based pharmacokinetic modelling (Journal article)
Huang, Z., & You, T. (2021). Personalise vitamin D <sub>3</sub> using physiologically based pharmacokinetic modelling. CPT: Pharmacometrics & Systems Pharmacology, 10(7), 723-734. doi:10.1002/psp4.12640DOI: 10.1002/psp4.12640
2018
A mathematical model of antibody-dependent cellular cytotoxicity (ADCC) (Journal article)
Hoffman, F., Gavaghan, D., Osborne, J., Barrett, I. P., You, T., Ghadially, H., . . . Byrne, H. M. (2018). A mathematical model of antibody-dependent cellular cytotoxicity (ADCC). Journal of Theoretical Biology, 436, 39-50. doi:10.1016/j.jtbi.2017.09.031DOI: 10.1016/j.jtbi.2017.09.031
2015
Investigating receptor enzyme activity using time‐scale analysis (Journal article)
You, T., & Yue, H. (2015). Investigating receptor enzyme activity using time‐scale analysis. IET Systems Biology, 9(6), 268-276. doi:10.1049/iet-syb.2015.0037DOI: 10.1049/iet-syb.2015.0037
2014
Time scale analysis of receptor enzyme activity: Irreversible inhibition sometimes exhibits incubation-time independence (Conference Paper)
You, T., & Yue, H. (2014). Time scale analysis of receptor enzyme activity: Irreversible inhibition sometimes exhibits incubation-time independence. In 2014 IEEE International Conference on Bioinformatics and Biomedicine (BIBM). IEEE. doi:10.1109/bibm.2014.6999257DOI: 10.1109/bibm.2014.6999257
Mechanisms Underlying the Exquisite Sensitivity of Candida albicans to Combinatorial Cationic and Oxidative Stress That Enhances the Potent Fungicidal Activity of Phagocytes (Journal article)
Kaloriti, D., Jacobsen, M., Yin, Z., Patterson, M., Tillmann, A., Smith, D. A., . . . Brown, A. J. P. (2014). Mechanisms Underlying the Exquisite Sensitivity of Candida albicans to Combinatorial Cationic and Oxidative Stress That Enhances the Potent Fungicidal Activity of Phagocytes. mBio, 5(4). doi:10.1128/mbio.01334-14DOI: 10.1128/mbio.01334-14
2013
Eukaryotic translation initiation factor interactions (Chapter)
You, T., Coghill, G., & Brown, A. (2013). Eukaryotic translation initiation factor interactions. In Encyclopedia of Systems Biology. Springer.
Translational control of GCN4 (Chapter)
You, T., Coghill, G., & Brown, A. (2013). Translational control of GCN4. In Encyclopedia of Systems Biology. Springer.
2012
A systems biology analysis of long and short-term memories of osmotic stress adaptation in fungi (Journal article)
You, T., Ingram, P., Jacobsen, M. D., Cook, E., McDonagh, A., Thorne, T., . . . Brown, A. J. P. (2012). A systems biology analysis of long and short-term memories of osmotic stress adaptation in fungi. BMC Research Notes, 5(1). doi:10.1186/1756-0500-5-258DOI: 10.1186/1756-0500-5-258
Combinatorial stresses kill pathogenic<i>Candida</i>species (Journal article)
Kaloriti, D., Tillmann, A., Cook, E., Jacobsen, M., You, T., Lenardon, M., . . . Brown, A. J. P. (2012). Combinatorial stresses kill pathogenic<i>Candida</i>species. Medical Mycology, 50(7), 699-709. doi:10.3109/13693786.2012.672770DOI: 10.3109/13693786.2012.672770
2011
Analysing GCN4 translational control in yeast by stochastic chemical kinetics modelling and simulation (Journal article)
You, T., Stansfield, I., Romano, M. C., Brown, A. J. P., & Coghill, G. M. (2011). Analysing GCN4 translational control in yeast by stochastic chemical kinetics modelling and simulation. BMC Systems Biology, 5(1). doi:10.1186/1752-0509-5-131DOI: 10.1186/1752-0509-5-131
2010
A quantitative model for mRNA translation in Saccharomyces cerevisiae (Journal article)
You, T., Coghill, G. M., & Brown, A. J. P. (n.d.). A quantitative model for mRNA translation in Saccharomyces cerevisiae. Yeast, 27(10), 785-800. doi:10.1002/yea.1770DOI: 10.1002/yea.1770
2009
Modelling and Simulation of Amino Acid Starvation Responses in Yeast Saccharomyces cerevisiae (Thesis / Dissertation)
You, T. (2009, May 23). Modelling and Simulation of Amino Acid Starvation Responses in Yeast Saccharomyces cerevisiae.
2006
Proteomic Analysis of Colorectal Cancer Reveals Alterations in Metabolic Pathways (Journal article)
Bi, X., Lin, Q., Foo, T. W., Joshi, S., You, T., Shen, H. -M., . . . Hew, C. -L. (2006). Proteomic Analysis of Colorectal Cancer Reveals Alterations in Metabolic Pathways. Molecular & Cellular Proteomics, 5(6), 1119-1130. doi:10.1074/mcp.m500432-mcp200DOI: 10.1074/mcp.m500432-mcp200
SPLASH: Systematic proteomics laboratory analysis and storage hub (Journal article)
Lo, S. L., You, T., Lin, Q., Joshi, S. B., Chung, M. C. M., & Hew, C. L. (2006). SPLASH: Systematic proteomics laboratory analysis and storage hub. PROTEOMICS, 6(6), 1758-1769. doi:10.1002/pmic.200500378DOI: 10.1002/pmic.200500378
