Professor Sarah Coupland MBBS, PhD, FRCPath, FARVO, FSB
George Holt Chair in Pathology, Honorary Consultant Histopathologist Molecular & Clinical Cancer Medicine
- +44 (0)151 706 5885 / +44 (0)151 794 9104
- Work email S.E.Coupland@liverpool.ac.uk
- Personal WebsiteMy research group: Liverpool Ocular Oncology Research Group
Research
Research Interest 1
Ocular oncology
Lymphoma; intraocular and ocular adnexal lymphomas
Uveal melanoma, conjunctival melanoma
Cutaneous melanoma
Research Group Membership
Research Grants
UM Cure 2020: New therapies for uveal melanoma
EUROPEAN COMMISSION
January 2016 - June 2021
To address DNA repair mechanisms in uveal melanoma
ROYAL LIVERPOOL AND BROADGREEN UNIVERSITY HOSPITALS NHS TRUST CHARITABLE FUNDS (UK)
October 2015 - March 2020
Exosome biogenesis: the role of sortilin in cancer development and progression
NORTH WEST CANCER RESEARCH INCORPORATING CLATTERBRIDGE CANCER RESEARCH - NWCR (UK)
January 2016 - April 2019
Liverpool Health Genomics Laboratory
LIVERPOOL HEALTH PARTNERS (UK)
March 2015 - February 2018
Joint PhD Studentship Between University of Szegad, Hungary and the University of Liverpool - Study to Investigate Tumour Associated Macrophages
ROYAL LIVERPOOL AND BROADGREEN UNIVERSITY HOSPITALS NHS TRUST CHARITABLE FUNDS (UK)
October 2015 - March 2019
2014 allocation - Wellcome ISSF non clinical fellowships
WELLCOME TRUST (UK)
May 2015 - October 2018
DTP studentships and cancer inequality research
NORTH WEST CANCER RESEARCH INCORPORATING CLATTERBRIDGE CANCER RESEARCH - NWCR (UK)
October 2015 - September 2022
Investigating in vivo resistance mechanisms to MEK inhibitors in uveal melanoma to enable novel combinatorial therapies.
NORTH WEST CANCER RESEARCH INCORPORATING CLATTERBRIDGE CANCER RESEARCH - NWCR (UK)
March 2016 - May 2019
Chick Embryo in vivo xenograft model for Ocular Cancer studies
BRITISH COUNCIL (UK)
April 2017 - March 2021
Bench fees - Sophie Thornton: Refining the Liverpool Uveal Melanoma Molecular Prognostication Model
ROYAL LIVERPOOL AND BROADGREEN UNIVERSITY HOSPITALS NHS TRUST CHARITABLE FUNDS (UK)
October 2016 - September 2020
Bridging Support for Associated Postdoctoral Research Assistant and Consumables
ROYAL LIVERPOOL AND BROADGREEN UNIVERSITY HOSPITALS NHS TRUST CHARITABLE FUNDS (UK)
April 2018 - December 2018
Northern (N6) Academic Pathology Network
INNOVATE UK (UK)
February 2019 - January 2023
North West Cancer Research Bid
NORTH WEST CANCER RESEARCH INCORPORATING CLATTERBRIDGE CANCER RESEARCH - NWCR (UK)
January 2018 - September 2023
PhD in Pathology
THE HIGHER COMMITTEE FOR EDUCATION DEVELOPMENT IN IRAQ (HCED) (IRAQ)
October 2015 - September 2020
Integrative analysis of BAP1-dependencies to identify novel therapeutic targets for uveal melanoma: learning lessons from the lung
FIGHT FOR SIGHT (UK)
October 2019 - September 2022
Uveal melanoma - PhD Studentship
ROYAL LIVERPOOL AND BROADGREEN UNIVERSITY HOSPITALS NHS TRUST CHARITABLE FUNDS (UK)
September 2010 - December 2021
Biosample collection from the SUAVE trial in uveal melanoma – TRANS-SUAVE
CANCER RESEARCH UK (CRUK) (UK)
November 2010 - October 2013
Investigation into Malt Lymphoma Project.
ROYAL LIVERPOOL AND BROADGREEN UNIVERSITY HOSPITALS NHS TRUST CHARITABLE FUNDS (UK)
November 2006 - July 2009
Metastasis in uveal melanoma study
ROYAL LIVERPOOL AND BROADGREEN UNIVERSITY HOSPITALS NHS TRUST CHARITABLE FUNDS (UK)
January 2012 - December 2012
Personalised epigenetic therapy for follicular lymphoma
CANCER RESEARCH UK (CRUK) (UK)
February 2013 - January 2016
Multiplex ligation-dependent probe amplification (MLPA) analysis in metastasizing cutaneous malignant melanoma.
NORTH WEST CANCER RESEARCH FUND
April 2008 - June 2009
Multiplex Ligation-Dependent Probe Amplification (MLPA) in Uveal Melanoma.
FIGHT FOR SIGHT (UK)
January 2008 - December 2009
Risk stratification: modelling and accessibility
ROYAL LIVERPOOL AND BROADGREEN UNIVERSITY HOSPITALS NHS TRUST (UK)
June 2010 - May 2011
Molecular characteristics of metastatic liver lesions in uveal melanoma: the search for therapeutic targets.
ROYAL LIVERPOOL AND BROADGREEN UNIVERSITY HOSPITALS NHS TRUST CHARITABLE FUNDS (UK)
January 2012 - December 2021
Molecular genetics of ocular tumours
ROYAL LIVERPOOL AND BROADGREEN UNIVERSITY HOSPITALS NHS TRUST (UK)
December 2010 - November 2015
Genetic abnormalities in conjunctival melanoma: a multicentre study
ROYAL LIVERPOOL AND BROADGREEN UNIVERSITY HOSPITALS NHS TRUST CHARITABLE FUNDS (UK)
February 2011 - August 2017
Stretching the supply routes: ErbB2 gene amplification and endocytic recycling in metastatic breast cancer
BREAST CANCER NOW (UK)
January 2015 - January 2019
Identification of regulators of metastasis in uveal melanoma
NORTH WEST CANCER RESEARCH FUND
October 2010 - March 2013
The development and characterisation of in vitro and in vivo models of uveal melanoma
ROYAL LIVERPOOL AND BROADGREEN UNIVERSITY HOSPITALS NHS TRUST CHARITABLE FUNDS (UK)
October 2012 - December 2015
Multiplex Ligation-Dependent Probe Amplification (MLPA) in Uveal Melanoma.
ROYAL LIVERPOOL AND BROADGREEN UNIVERSITY HOSPITALS NHS TRUST (UK)
January 2010 - June 2010
PACIFICO Phase III multicentre trial comparing two different Rituximab-Chemotherapy induction regimens for Follicular Lymphoma in Older patients (PACIFIC)
CANCER RESEARCH UK (CRUK) (UK)
November 2008 - July 2021
Applying innovative technologies to improve the benefit-risk ratio of drugs: developing a national resource underpinned by the infrastructure of the MRC Centre for Drug Safety Science
MEDICAL RESEARCH COUNCIL (MRC)
April 2015 - March 2016
Novel isogenic models of BAP1-deficient uveal melanoma for drug discovery
FIGHT FOR SIGHT (UK)
October 2014 - September 2018
The role of exosomes in uveal melanoma
THE PATHOLOGICAL SOCIETY (UK)
October 2014 - December 2020
Multiplex ligation-dependent probe amplification (MLPA) assessment of clinical uveal melanoma (UM) samples
ROYAL LIVERPOOL AND BROADGREEN UNIVERSITY HOSPITALS NHS TRUST (UK)
March 2009 - February 2015
Identification of regulators of metastasis in uveal melanoma (UM)
CANCER RESEARCH UK (CRUK) (UK)
July 2010 - March 2014
Multiplex ligation-dependent probe amplification (MLPA)in Uveal Melanoma.
ROYAL LIVERPOOL AND BROADGREEN UNIVERSITY HOSPITALS NHS TRUST CHARITABLE FUNDS (UK)
September 2007 - August 2010
The role of chemokines and integrins in the localisation of B-cell Non-Hodgkin’s Lymphomas (B-NHL)
LYMPHOMA RESEARCH TRUST
January 2013 - December 2013
CR-UK Cancer Research Centre - Infrastructure Grant 2012-14
CANCER RESEARCH UK (CRUK) (UK)
November 2012 - March 2015
Ocular oncology research
CLATTERBRIDGE CENTRE FOR ONCOLOGY, ROYAL LIVERPOOL AND BROADGREEN UNIVERSITY HOSPITALS NHS TRUST (UK), THE CLATTERBRIDGE CANCER CENTRE NHS FOUNDATION TRUST (UK)
February 2008 - January 2020
Bench fees for Rasha Swadi
REPUBLIC OF IRAQ MINISTRY OF EDUCATION
October 2014 - September 2018
The North West Cancer Research Cancer Centre
NORTH WEST CANCER RESEARCH INCORPORATING CLATTERBRIDGE CANCER RESEARCH - NWCR (UK)
April 2014 - September 2023
Biosample collection from the ITEM trial in Uveal Melanoma.
CANCER RESEARCH UK (CRUK) (UK)
September 2008 - February 2011
Bench fees to support PhD student Omar Alishlash
THE HIGHER COMMITTEE FOR EDUCATION DEVELOPMENT IN IRAQ (HCED) (IRAQ)
January 2013 - December 2015
Impact of tumour-associated myeloid cells on cancer stemness and chemotherapy-resistance
NORTH WEST CANCER RESEARCH FUND
March 2013 - December 2016
NITRO Trial: Neoadjuvant IntraviTreal Ranibizumab treatment in high risk Ocular melanoma patients: A two stage single centre Phase II single arm study.
CANCER RESEARCH UK (CRUK) (UK), ROYAL LIVERPOOL AND BROADGREEN UNIVERSITY HOSPITALS NHS TRUST (UK)
October 2011 - September 2015
Research Collaborations
Henrik Vorum, Bent Honoré, Steen Fiil Urbak
External: University of Aarhus, Denmark
Examining proteomics of uveal melanomas with and without monosomy 3
Paul Finger
External: American Joint Committee Against Cancer (AJCC)
Committee member revising and designing staging systems of the tumours in and around the eye