Professor Sarah Coupland MBBS, PhD, FRCPath, FARVO, FSB
George Holt Chair in Pathology, Honorary Consultant Histopathologist Molecular & Clinical Cancer Medicine
- +44 (0)151 706 5885 / +44 (0)151 794 9104
- Work email S.E.Coupland@liverpool.ac.uk
- Personal WebsiteMy research group: Liverpool Ocular Oncology Research Group
Research
Research Interest 1
Ocular oncology
Lymphoma; intraocular and ocular adnexal lymphomas
Uveal melanoma, conjunctival melanoma
Cutaneous melanoma
Research Group Membership
Research Grants
Modelling the interplay between uveal melanoma cells and macrophages
SIGHT RESEARCH UK (UK)
February 2022 - November 2022
UM Cure 2020: New therapies for uveal melanoma
EUROPEAN COMMISSION
January 2016 - June 2021
To address DNA repair mechanisms in uveal melanoma
ROYAL LIVERPOOL AND BROADGREEN UNIVERSITY HOSPITALS NHS TRUST CHARITABLE FUNDS (UK)
October 2015 - March 2020
Exosome biogenesis: the role of sortilin in cancer development and progression
NORTH WEST CANCER RESEARCH INCORPORATING CLATTERBRIDGE CANCER RESEARCH - NWCR (UK)
January 2016 - April 2019
Liverpool Health Genomics Laboratory
LIVERPOOL HEALTH PARTNERS (UK)
March 2015 - February 2018
Joint PhD Studentship Between University of Szegad, Hungary and the University of Liverpool - Study to Investigate Tumour Associated Macrophages
ROYAL LIVERPOOL AND BROADGREEN UNIVERSITY HOSPITALS NHS TRUST CHARITABLE FUNDS (UK)
October 2015 - March 2019
2014 allocation - Wellcome ISSF non clinical fellowships
WELLCOME TRUST (UK)
May 2015 - October 2018
DTP studentships and cancer inequality research
NORTH WEST CANCER RESEARCH INCORPORATING CLATTERBRIDGE CANCER RESEARCH - NWCR (UK)
October 2015 - September 2022
Investigating in vivo resistance mechanisms to MEK inhibitors in uveal melanoma to enable novel combinatorial therapies.
NORTH WEST CANCER RESEARCH INCORPORATING CLATTERBRIDGE CANCER RESEARCH - NWCR (UK)
March 2016 - May 2019
Chick Embryo in vivo xenograft model for Ocular Cancer studies
BRITISH COUNCIL (UK)
April 2017 - March 2021
Bench fees - Sophie Thornton: Refining the Liverpool Uveal Melanoma Molecular Prognostication Model
ROYAL LIVERPOOL AND BROADGREEN UNIVERSITY HOSPITALS NHS TRUST CHARITABLE FUNDS (UK)
October 2016 - September 2020
Bridging Support for Associated Postdoctoral Research Assistant and Consumables
ROYAL LIVERPOOL AND BROADGREEN UNIVERSITY HOSPITALS NHS TRUST CHARITABLE FUNDS (UK)
April 2018 - December 2018
Northern (N6) Academic Pathology Network
INNOVATE UK (UK)
February 2019 - January 2023
North West Cancer Research Bid
NORTH WEST CANCER RESEARCH INCORPORATING CLATTERBRIDGE CANCER RESEARCH - NWCR (UK)
January 2018 - September 2023
PhD in Pathology
THE HIGHER COMMITTEE FOR EDUCATION DEVELOPMENT IN IRAQ (HCED) (IRAQ)
October 2015 - September 2020
Integrative analysis of BAP1-dependencies to identify novel therapeutic targets for uveal melanoma: learning lessons from the lung
FIGHT FOR SIGHT (UK)
October 2019 - December 2022
Uveal melanoma - PhD Studentship
ROYAL LIVERPOOL AND BROADGREEN UNIVERSITY HOSPITALS NHS TRUST CHARITABLE FUNDS (UK)
September 2010 - December 2022
Biosample collection from the SUAVE trial in uveal melanoma – TRANS-SUAVE
CANCER RESEARCH UK (CRUK) (UK)
November 2010 - October 2013
Investigation into Malt Lymphoma Project.
ROYAL LIVERPOOL AND BROADGREEN UNIVERSITY HOSPITALS NHS TRUST CHARITABLE FUNDS (UK)
November 2006 - July 2009
Metastasis in uveal melanoma study
ROYAL LIVERPOOL AND BROADGREEN UNIVERSITY HOSPITALS NHS TRUST CHARITABLE FUNDS (UK)
January 2012 - December 2012
Personalised epigenetic therapy for follicular lymphoma
CANCER RESEARCH UK (CRUK) (UK)
February 2013 - January 2016
Multiplex ligation-dependent probe amplification (MLPA) analysis in metastasizing cutaneous malignant melanoma.
NORTH WEST CANCER RESEARCH FUND
April 2008 - June 2009
Multiplex Ligation-Dependent Probe Amplification (MLPA) in Uveal Melanoma.
FIGHT FOR SIGHT (UK)
January 2008 - December 2009
Risk stratification: modelling and accessibility
ROYAL LIVERPOOL AND BROADGREEN UNIVERSITY HOSPITALS NHS TRUST (UK)
June 2010 - May 2011
Molecular characteristics of metastatic liver lesions in uveal melanoma: the search for therapeutic targets.
ROYAL LIVERPOOL AND BROADGREEN UNIVERSITY HOSPITALS NHS TRUST CHARITABLE FUNDS (UK)
January 2012 - December 2022
Molecular genetics of ocular tumours
ROYAL LIVERPOOL AND BROADGREEN UNIVERSITY HOSPITALS NHS TRUST (UK)
December 2010 - November 2015
Genetic abnormalities in conjunctival melanoma: a multicentre study
ROYAL LIVERPOOL AND BROADGREEN UNIVERSITY HOSPITALS NHS TRUST CHARITABLE FUNDS (UK)
February 2011 - August 2017
Stretching the supply routes: ErbB2 gene amplification and endocytic recycling in metastatic breast cancer
BREAST CANCER NOW (UK)
January 2015 - January 2019
Identification of regulators of metastasis in uveal melanoma
NORTH WEST CANCER RESEARCH FUND
October 2010 - March 2013
The development and characterisation of in vitro and in vivo models of uveal melanoma
ROYAL LIVERPOOL AND BROADGREEN UNIVERSITY HOSPITALS NHS TRUST CHARITABLE FUNDS (UK)
October 2012 - December 2015
Multiplex Ligation-Dependent Probe Amplification (MLPA) in Uveal Melanoma.
ROYAL LIVERPOOL AND BROADGREEN UNIVERSITY HOSPITALS NHS TRUST (UK)
January 2010 - June 2010
PACIFICO Phase III multicentre trial comparing two different Rituximab-Chemotherapy induction regimens for Follicular Lymphoma in Older patients (PACIFIC)
CANCER RESEARCH UK (CRUK) (UK)
November 2008 - July 2021
Applying innovative technologies to improve the benefit-risk ratio of drugs: developing a national resource underpinned by the infrastructure of the MRC Centre for Drug Safety Science
MEDICAL RESEARCH COUNCIL (MRC)
April 2015 - March 2016
Novel isogenic models of BAP1-deficient uveal melanoma for drug discovery
FIGHT FOR SIGHT (UK)
October 2014 - September 2018
The role of exosomes in uveal melanoma
THE PATHOLOGICAL SOCIETY (UK)
October 2014 - December 2020
Multiplex ligation-dependent probe amplification (MLPA) assessment of clinical uveal melanoma (UM) samples
ROYAL LIVERPOOL AND BROADGREEN UNIVERSITY HOSPITALS NHS TRUST (UK)
March 2009 - February 2015
Identification of regulators of metastasis in uveal melanoma (UM)
CANCER RESEARCH UK (CRUK) (UK)
July 2010 - March 2014
Multiplex ligation-dependent probe amplification (MLPA)in Uveal Melanoma.
ROYAL LIVERPOOL AND BROADGREEN UNIVERSITY HOSPITALS NHS TRUST CHARITABLE FUNDS (UK)
September 2007 - August 2010
The role of chemokines and integrins in the localisation of B-cell Non-Hodgkin’s Lymphomas (B-NHL)
LYMPHOMA RESEARCH TRUST
January 2013 - December 2013
CR-UK Cancer Research Centre - Infrastructure Grant 2012-14
CANCER RESEARCH UK (CRUK) (UK)
November 2012 - March 2015
Ocular oncology research
CLATTERBRIDGE CENTRE FOR ONCOLOGY, ROYAL LIVERPOOL AND BROADGREEN UNIVERSITY HOSPITALS NHS TRUST (UK), THE CLATTERBRIDGE CANCER CENTRE NHS FOUNDATION TRUST (UK)
February 2008 - January 2020
Bench fees for Rasha Swadi
REPUBLIC OF IRAQ MINISTRY OF EDUCATION
October 2014 - September 2018
The North West Cancer Research Cancer Centre
NORTH WEST CANCER RESEARCH INCORPORATING CLATTERBRIDGE CANCER RESEARCH - NWCR (UK)
April 2014 - September 2023
Biosample collection from the ITEM trial in Uveal Melanoma.
CANCER RESEARCH UK (CRUK) (UK)
September 2008 - February 2011
Bench fees to support PhD student Omar Alishlash
THE HIGHER COMMITTEE FOR EDUCATION DEVELOPMENT IN IRAQ (HCED) (IRAQ)
January 2013 - December 2015
Impact of tumour-associated myeloid cells on cancer stemness and chemotherapy-resistance
NORTH WEST CANCER RESEARCH FUND
March 2013 - December 2016
NITRO Trial: Neoadjuvant IntraviTreal Ranibizumab treatment in high risk Ocular melanoma patients: A two stage single centre Phase II single arm study.
CANCER RESEARCH UK (CRUK) (UK), ROYAL LIVERPOOL AND BROADGREEN UNIVERSITY HOSPITALS NHS TRUST (UK)
October 2011 - September 2015
Research Collaborations
Henrik Vorum, Bent Honoré, Steen Fiil Urbak
External: University of Aarhus, Denmark
Examining proteomics of uveal melanomas with and without monosomy 3
Paul Finger
External: American Joint Committee Against Cancer (AJCC)
Committee member revising and designing staging systems of the tumours in and around the eye