Professor Sarah Coupland MBBS, PhD, FRCPath, FARVO, FSB

Research Grants

Development of a novel chick embryo model to discover and investigate therapeutics for uveal melanoma metastatic to the liver.

NORTH WEST CANCER RESEARCH INCORPORATING CLATTERBRIDGE CANCER RESEARCH (UK)

September 2023 - June 2027

Advances in 3D cellular modelling of uveal melanoma: exploring the generation and utilisation of uveal melanoma cancer organoids.

THE PATHOLOGICAL SOCIETY (UK)

February 2023 - April 2024

LAG-3 expression in solid tumours

BRISTOL-MYERS SQUIBB PHARMACEUTICALS LTD (UK)

March 2022 - September 2022

Modelling the interplay between uveal melanoma cells and macrophages

SIGHT RESEARCH UK (UK)

February 2022 - February 2023

UM Cure 2020: New therapies for uveal melanoma

EUROPEAN COMMISSION

January 2016 - June 2021

To address DNA repair mechanisms in uveal melanoma

ROYAL LIVERPOOL AND BROADGREEN UNIVERSITY HOSPITALS NHS TRUST CHARITABLE FUNDS (UK)

October 2015 - March 2020

Exosome biogenesis: the role of sortilin in cancer development and progression

NORTH WEST CANCER RESEARCH INCORPORATING CLATTERBRIDGE CANCER RESEARCH (UK)

January 2016 - April 2019

Liverpool Health Genomics Laboratory

LIVERPOOL HEALTH PARTNERS (UK)

March 2015 - February 2018

Joint PhD Studentship Between University of Szegad, Hungary and the University of Liverpool - Study to Investigate Tumour Associated Macrophages

ROYAL LIVERPOOL AND BROADGREEN UNIVERSITY HOSPITALS NHS TRUST CHARITABLE FUNDS (UK)

October 2015 - March 2019

2014 allocation - Wellcome ISSF non clinical fellowships

WELLCOME TRUST (UK)

May 2015 - October 2018

DTP studentships and cancer inequality research

NORTH WEST CANCER RESEARCH INCORPORATING CLATTERBRIDGE CANCER RESEARCH (UK)

October 2015 - September 2022

Investigating in vivo resistance mechanisms to MEK inhibitors in uveal melanoma to enable novel combinatorial therapies.

NORTH WEST CANCER RESEARCH INCORPORATING CLATTERBRIDGE CANCER RESEARCH (UK)

March 2016 - May 2019

Chick Embryo in vivo xenograft model for Ocular Cancer studies

BRITISH COUNCIL (UK)

April 2017 - March 2021

Bench fees - Sophie Thornton: Refining the Liverpool Uveal Melanoma Molecular Prognostication Model

ROYAL LIVERPOOL AND BROADGREEN UNIVERSITY HOSPITALS NHS TRUST CHARITABLE FUNDS (UK)

October 2016 - September 2020

Bridging Support for Associated Postdoctoral Research Assistant and Consumables

ROYAL LIVERPOOL AND BROADGREEN UNIVERSITY HOSPITALS NHS TRUST CHARITABLE FUNDS (UK)

April 2018 - December 2018

The Northern Pathology Imaging Collaborative

INNOVATE UK (UK)

February 2019 - March 2023

North West Cancer Research Bid

NORTH WEST CANCER RESEARCH INCORPORATING CLATTERBRIDGE CANCER RESEARCH (UK)

January 2018 - September 2023

PhD in Pathology

THE HIGHER COMMITTEE FOR EDUCATION DEVELOPMENT IN IRAQ (HCED) (IRAQ)

October 2015 - September 2020

Integrative analysis of BAP1-dependencies to identify novel therapeutic targets for uveal melanoma: learning lessons from the lung

FIGHT FOR SIGHT (UK)

October 2019 - December 2022

Uveal melanoma - PhD Studentship

ROYAL LIVERPOOL AND BROADGREEN UNIVERSITY HOSPITALS NHS TRUST CHARITABLE FUNDS (UK)

September 2010 - December 2022

Biosample collection from the SUAVE trial in uveal melanoma – TRANS-SUAVE

CANCER RESEARCH UK (UK)

November 2010 - October 2013

Investigation into Malt Lymphoma Project.

ROYAL LIVERPOOL AND BROADGREEN UNIVERSITY HOSPITALS NHS TRUST CHARITABLE FUNDS (UK)

November 2006 - July 2009

Metastasis in uveal melanoma study

ROYAL LIVERPOOL AND BROADGREEN UNIVERSITY HOSPITALS NHS TRUST CHARITABLE FUNDS (UK)

January 2012 - December 2012

Personalised epigenetic therapy for follicular lymphoma

CANCER RESEARCH UK (UK)

February 2013 - January 2016

Multiplex ligation-dependent probe amplification (MLPA) analysis in metastasizing cutaneous malignant melanoma.

NORTH WEST CANCER RESEARCH FUND

April 2008 - June 2009

Multiplex Ligation-Dependent Probe Amplification (MLPA) in Uveal Melanoma.

FIGHT FOR SIGHT (UK)

January 2008 - December 2009

Risk stratification: modelling and accessibility

ROYAL LIVERPOOL AND BROADGREEN UNIVERSITY HOSPITALS NHS TRUST (UK)

June 2010 - May 2011

Molecular characteristics of metastatic liver lesions in uveal melanoma: the search for therapeutic targets.

ROYAL LIVERPOOL AND BROADGREEN UNIVERSITY HOSPITALS NHS TRUST CHARITABLE FUNDS (UK)

January 2012 - March 2024

Molecular genetics of ocular tumours

ROYAL LIVERPOOL AND BROADGREEN UNIVERSITY HOSPITALS NHS TRUST (UK)

December 2010 - November 2015

Genetic abnormalities in conjunctival melanoma: a multicentre study

ROYAL LIVERPOOL AND BROADGREEN UNIVERSITY HOSPITALS NHS TRUST CHARITABLE FUNDS (UK)

February 2011 - August 2017

Stretching the supply routes: ErbB2 gene amplification and endocytic recycling in metastatic breast cancer

BREAST CANCER NOW (UK)

January 2015 - January 2019

Identification of regulators of metastasis in uveal melanoma

NORTH WEST CANCER RESEARCH FUND

October 2010 - March 2013

The development and characterisation of in vitro and in vivo models of uveal melanoma

ROYAL LIVERPOOL AND BROADGREEN UNIVERSITY HOSPITALS NHS TRUST CHARITABLE FUNDS (UK)

October 2012 - December 2015

Multiplex Ligation-Dependent Probe Amplification (MLPA) in Uveal Melanoma.

ROYAL LIVERPOOL AND BROADGREEN UNIVERSITY HOSPITALS NHS TRUST (UK)

January 2010 - June 2010

PACIFICO Phase III multicentre trial comparing two different Rituximab-Chemotherapy induction regimens for Follicular Lymphoma in Older patients (PACIFIC)

CANCER RESEARCH UK (UK)

November 2008 - July 2021

Applying innovative technologies to improve the benefit-risk ratio of drugs: developing a national resource underpinned by the infrastructure of the MRC Centre for Drug Safety Science

MEDICAL RESEARCH COUNCIL

April 2015 - March 2016

Novel isogenic models of BAP1-deficient uveal melanoma for drug discovery

FIGHT FOR SIGHT (UK)

October 2014 - September 2018

The role of exosomes in uveal melanoma

THE PATHOLOGICAL SOCIETY (UK)

October 2014 - December 2020

Multiplex ligation-dependent probe amplification (MLPA) assessment of clinical uveal melanoma (UM) samples

ROYAL LIVERPOOL AND BROADGREEN UNIVERSITY HOSPITALS NHS TRUST (UK)

March 2009 - February 2015

Identification of regulators of metastasis in uveal melanoma (UM)

CANCER RESEARCH UK (UK)

July 2010 - March 2014

Multiplex ligation-dependent probe amplification (MLPA)in Uveal Melanoma.

ROYAL LIVERPOOL AND BROADGREEN UNIVERSITY HOSPITALS NHS TRUST CHARITABLE FUNDS (UK)

September 2007 - August 2010

The role of chemokines and integrins in the localisation of B-cell Non-Hodgkin’s Lymphomas (B-NHL)

LYMPHOMA RESEARCH TRUST

January 2013 - December 2013

CR-UK Cancer Research Centre - Infrastructure Grant 2012-14

CANCER RESEARCH UK (UK)

November 2012 - March 2015

Ocular oncology research

CLATTERBRIDGE CENTRE FOR ONCOLOGY, ROYAL LIVERPOOL AND BROADGREEN UNIVERSITY HOSPITALS NHS TRUST (UK), THE CLATTERBRIDGE CANCER CENTRE NHS FOUNDATION TRUST (UK)

February 2008 - January 2020

Bench fees for Rasha Swadi

REPUBLIC OF IRAQ MINISTRY OF EDUCATION🚩

October 2014 - September 2018

The North West Cancer Research Cancer Centre

NORTH WEST CANCER RESEARCH INCORPORATING CLATTERBRIDGE CANCER RESEARCH (UK)

April 2014 - September 2023

Biosample collection from the ITEM trial in Uveal Melanoma.

CANCER RESEARCH UK (UK)

September 2008 - February 2011

Bench fees to support PhD student Omar Alishlash

THE HIGHER COMMITTEE FOR EDUCATION DEVELOPMENT IN IRAQ (HCED) (IRAQ)

January 2013 - December 2015

Impact of tumour-associated myeloid cells on cancer stemness and chemotherapy-resistance

NORTH WEST CANCER RESEARCH FUND

March 2013 - December 2016

NITRO Trial: Neoadjuvant IntraviTreal Ranibizumab treatment in high risk Ocular melanoma patients: A two stage single centre Phase II single arm study.

CANCER RESEARCH UK (UK), ROYAL LIVERPOOL AND BROADGREEN UNIVERSITY HOSPITALS NHS TRUST (UK)

October 2011 - September 2015

Research Collaborations