Our current work is focused on the mechanisms of regulated transcript degradation and the link between translation and the modification of RNA, which involves the addition of a short pyrimidine tags to the transcripts. This tag marks transcripts for silencing, triggering a shift in their subcellular localisation and promoting rapid degradation. Additional interest include: whole transcriptome sequencing to define the functional genome; nitrogen metabolism and its regulation; the application of comparative genomics to decipher the regulatory code.
Prizes or Honours
- EUROFUNG executive committee member (EUROFUNGBASE consortium, 2010)
- Member of Aspergillus genomic tools working group (Aspergillus Genomes Research Policy Committee , 2005)
- Member of Aspegillus niger annotation team - heading transcription factor analysis (DSM , 2005)
- Member of Aspergillus Genome Annotation - to head signalling and transcription (Genome consortimu including TIGR & Sanger center/, 2003)