2020
Shukla, R., Medeiros-Silva, J., Parmar, A., Vermeulen, B. J. A., Das, S., Paioni, A. L., . . . Weingarth, M. (2020). Mode of action of teixobactins in cellular membranes. Nature Communications, 11(1). doi:10.1038/s41467-020-16600-2DOI: 10.1038/s41467-020-16600-2
2018
Cysteines and Disulfide-Bridged Macrocyclic Mimics of Teixobactin Analogues and Their Antibacterial Activity Evaluation against Methicillin-Resistant Staphylococcus Aureus (MRSA) (Journal article)
Malkawi, R., Iyer, A., Parmar, A., Lloyd, D. G., Goh, E. T. L., Taylor, E. J., . . . Singh, I. (2018). Cysteines and Disulfide-Bridged Macrocyclic Mimics of Teixobactin Analogues and Their Antibacterial Activity Evaluation against Methicillin-Resistant Staphylococcus Aureus (MRSA). PHARMACEUTICS, 10(4). doi:10.3390/pharmaceutics10040183DOI: 10.3390/pharmaceutics10040183
Design and Syntheses of Highly Potent Teixobactin Analogues against Staphylococcus aureus, Methicillin-Resistant Staphylococcus aureus (MRSA), and Vancomycin-Resistant Enterococci (VRE) in Vitro and in Vivo (Journal article)
Parmar, A., Lakshminarayanan, R., Iyer, A., Mayandi, V., Goh, E. T. L., Lloyd, D. G., . . . Singh, I. (2018). Design and Syntheses of Highly Potent Teixobactin Analogues against Staphylococcus aureus, Methicillin-Resistant Staphylococcus aureus (MRSA), and Vancomycin-Resistant Enterococci (VRE) in Vitro and in Vivo. JOURNAL OF MEDICINAL CHEMISTRY, 61(5), 2009-2017. doi:10.1021/acs.jmedchem.7b01634DOI: 10.1021/acs.jmedchem.7b01634
2017
Teixobactin analogues reveal enduracididine to be non-essential for highly potent antibacterial activity and lipid II binding (Journal article)
Parmar, A., Iyer, A., Prior, S. H., Lloyd, D. G., Goh, E. T. L., Vincent, C. S., . . . Singh, I. (2017). Teixobactin analogues reveal enduracididine to be non-essential for highly potent antibacterial activity and lipid II binding. CHEMICAL SCIENCE, 8(12), 8183-8192. doi:10.1039/c7sc03241bDOI: 10.1039/c7sc03241b
Syntheses of potent teixobactin analogues against methicillin-resistant Staphylococcus aureus (MRSA) through the replacement of L-allo-enduracididine with its isosteres (Journal article)
Parmar, A., Iyer, A., Lloyd, D. G., Vincent, C. S., Prior, S. H., Madder, A., . . . Singh, I. (2017). Syntheses of potent teixobactin analogues against methicillin-resistant Staphylococcus aureus (MRSA) through the replacement of L-allo-enduracididine with its isosteres. CHEMICAL COMMUNICATIONS, 53(55), 7788-7791. doi:10.1039/c7cc04021kDOI: 10.1039/c7cc04021k
Defining the molecular structure of teixobactin analogues and understanding their role in antibacterial activities (Journal article)
Parmar, A., Prior, S. H., Iyer, A., Vincent, C. S., Van Lysebetten, D., Breukink, E., . . . Singh, I. (2017). Defining the molecular structure of teixobactin analogues and understanding their role in antibacterial activities. CHEMICAL COMMUNICATIONS, 53(12), 2016-2019. doi:10.1039/c6cc09490bDOI: 10.1039/c6cc09490b
2016
Efficient total syntheses and biological activities of two teixobactin analogues (Journal article)
Parmar, A., Iyer, A., Vincent, C. S., Van Lysebetten, D., Prior, S. H., Madder, A., . . . Singh, I. (2016). Efficient total syntheses and biological activities of two teixobactin analogues. CHEMICAL COMMUNICATIONS, 52(36), 6060-6063. doi:10.1039/c5cc10249aDOI: 10.1039/c5cc10249a
