Dr Anish Parmar

Post-Doctoral Research Associate Pharmacology & Therapeutics

Work email Anish.Parmar@liverpool.ac.uk

Publications

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2020

Mode of action of teixobactins in cellular membranes (Journal article)

Shukla, R., Medeiros-Silva, J., Parmar, A., Vermeulen, B. J. A., Das, S., Paioni, A. L., . . . Weingarth, M. (2020). Mode of action of teixobactins in cellular membranes. Nature Communications, 11(1). doi:10.1038/s41467-020-16600-2

DOI: 10.1038/s41467-020-16600-2

2018

Cysteines and Disulfide-Bridged Macrocyclic Mimics of Teixobactin Analogues and Their Antibacterial Activity Evaluation against Methicillin-Resistant Staphylococcus Aureus (MRSA) (Journal article)

Malkawi, R., Iyer, A., Parmar, A., Lloyd, D. G., Goh, E. T. L., Taylor, E. J., . . . Singh, I. (2018). Cysteines and Disulfide-Bridged Macrocyclic Mimics of Teixobactin Analogues and Their Antibacterial Activity Evaluation against Methicillin-Resistant Staphylococcus Aureus (MRSA). PHARMACEUTICS, 10(4). doi:10.3390/pharmaceutics10040183

DOI: 10.3390/pharmaceutics10040183

Design and Syntheses of Highly Potent Teixobactin Analogues against Staphylococcus aureus, Methicillin-Resistant Staphylococcus aureus (MRSA), and Vancomycin-Resistant Enterococci (VRE) in Vitro and in Vivo (Journal article)

Parmar, A., Lakshminarayanan, R., Iyer, A., Mayandi, V., Goh, E. T. L., Lloyd, D. G., . . . Singh, I. (2018). Design and Syntheses of Highly Potent Teixobactin Analogues against Staphylococcus aureus, Methicillin-Resistant Staphylococcus aureus (MRSA), and Vancomycin-Resistant Enterococci (VRE) in Vitro and in Vivo. JOURNAL OF MEDICINAL CHEMISTRY, 61(5), 2009-2017. doi:10.1021/acs.jmedchem.7b01634

DOI: 10.1021/acs.jmedchem.7b01634

2017

Teixobactin analogues reveal enduracididine to be non-essential for highly potent antibacterial activity and lipid II binding (Journal article)

Parmar, A., Iyer, A., Prior, S. H., Lloyd, D. G., Goh, E. T. L., Vincent, C. S., . . . Singh, I. (2017). Teixobactin analogues reveal enduracididine to be non-essential for highly potent antibacterial activity and lipid II binding. CHEMICAL SCIENCE, 8(12), 8183-8192. doi:10.1039/c7sc03241b

DOI: 10.1039/c7sc03241b

Syntheses of potent teixobactin analogues against methicillin-resistant Staphylococcus aureus (MRSA) through the replacement of L-allo-enduracididine with its isosteres (Journal article)

Parmar, A., Iyer, A., Lloyd, D. G., Vincent, C. S., Prior, S. H., Madder, A., . . . Singh, I. (2017). Syntheses of potent teixobactin analogues against methicillin-resistant Staphylococcus aureus (MRSA) through the replacement of L-allo-enduracididine with its isosteres. CHEMICAL COMMUNICATIONS, 53(55), 7788-7791. doi:10.1039/c7cc04021k

DOI: 10.1039/c7cc04021k

Defining the molecular structure of teixobactin analogues and understanding their role in antibacterial activities (Journal article)

Parmar, A., Prior, S. H., Iyer, A., Vincent, C. S., Van Lysebetten, D., Breukink, E., . . . Singh, I. (2017). Defining the molecular structure of teixobactin analogues and understanding their role in antibacterial activities. CHEMICAL COMMUNICATIONS, 53(12), 2016-2019. doi:10.1039/c6cc09490b

DOI: 10.1039/c6cc09490b

2016

Efficient total syntheses and biological activities of two teixobactin analogues (Journal article)

Parmar, A., Iyer, A., Vincent, C. S., Van Lysebetten, D., Prior, S. H., Madder, A., . . . Singh, I. (2016). Efficient total syntheses and biological activities of two teixobactin analogues. CHEMICAL COMMUNICATIONS, 52(36), 6060-6063. doi:10.1039/c5cc10249a

DOI: 10.1039/c5cc10249a

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