Publications
2024
A core outcome set for best care for the dying person: Results of an international Delphi study and consensus meeting.
Zambrano, S. C., Egloff, M., Gonzalez-Jaramillo, V., Christen-Cevallos Rosero, A., Allan, S., Barnestein-Fonseca, P., . . . iLIVE. (2024). A core outcome set for best care for the dying person: Results of an international Delphi study and consensus meeting.. Palliative medicine, 2692163241300867. doi:10.1177/02692163241300867
Epilepsy core outcome set for effectiveness trials (EPSET): A systematic review of outcomes measured in registered phase III and IV clinical trials for adults with epilepsy.
Mitchell, J. W., Batchelor, R., Adan, G., Noble, A., Williamson, P. R., & Marson, T. (2024). Epilepsy core outcome set for effectiveness trials (EPSET): A systematic review of outcomes measured in registered phase III and IV clinical trials for adults with epilepsy.. Epilepsy research, 209, 107481. doi:10.1016/j.eplepsyres.2024.107481
P19.13.A RESULTS FROM THE COSMIC PROJECT: CORE OUTCOME SETS FOR MENINGIOMA IN CLINICAL EFFECTIVENESS STUDIES
Jenkinson, M. D., Millward, C. P., Islim, A. I., Keshwara, S. M., Srikandarajah, N., Brodbelt, A. R., . . . Williamson, P. R. (2024). P19.13.A RESULTS FROM THE COSMIC PROJECT: CORE OUTCOME SETS FOR MENINGIOMA IN CLINICAL EFFECTIVENESS STUDIES. Neuro-Oncology, 26(Supplement_5), v114. doi:10.1093/neuonc/noae144.383
The effects of ciclosporin and methotrexate on kidney function in the treatment of severe atopic dermatitis in children: results from the TREAT trial.
Bruce, G., Rosala-Hallas, A., Jones, A. P., Turner, C., Dalton, N., Hilger, E., . . . Flohr, C. (2024). The effects of ciclosporin and methotrexate on kidney function in the treatment of severe atopic dermatitis in children: results from the TREAT trial.. The British journal of dermatology, 191(5), 851-852. doi:10.1093/bjd/ljae276
How professional development can be supported for health and care research methodologists: results of the PROfesSionnal develoPmEnt for Research methodologists (PROSPER) e-Delphi and consensus study.
Iflaifel, M., Williamson, P. R., & Mitchell, E. J. (2024). How professional development can be supported for health and care research methodologists: results of the PROfesSionnal develoPmEnt for Research methodologists (PROSPER) e-Delphi and consensus study.. BMJ open, 14(10), e085656. doi:10.1136/bmjopen-2024-085656
What is the carbon footprint of academic clinical trials? A study of hotspots in 10 trials.
Griffiths, J., Adshead, F., Al-Shahi Salman, R., Anderson, C., Bedson, E., Bliss, J., . . . Williamson, P. R. (2024). What is the carbon footprint of academic clinical trials? A study of hotspots in 10 trials.. BMJ open, 14(10), e088600. doi:10.1136/bmjopen-2024-088600
Core outcome set for intervention research on snakebite envenomation in South Asia.
Bhaumik, S., Beri, D., Santra, V., Gopalakrishnan, M., Faiz, M. A., Williamson, P. R., . . . Jagnoor, J. (2024). Core outcome set for intervention research on snakebite envenomation in South Asia.. Injury prevention : journal of the International Society for Child and Adolescent Injury Prevention, ip-2023-045155. doi:10.1136/ip-2023-045155
Editorial: The relevance of core outcome sets to clinical guideline development
Rhodes, S., Williamson, P., & Florez, I. D. (2024). Editorial: The relevance of core outcome sets to clinical guideline development. Clinical and Public Health Guidelines, 1(4). doi:10.1002/gin2.12026
PRACTICE: Development of a Core Outcome Set for Trials of Physical Rehabilitation in Critical Illness.
Connolly, B. A., Barclay, M., Davies, C., Hart, N., Pattison, N., Sturmey, G., . . . Blackwood, B. (2024). PRACTICE: Development of a Core Outcome Set for Trials of Physical Rehabilitation in Critical Illness.. Annals of the American Thoracic Society, 21(12), 1742-1750. doi:10.1513/annalsats.202406-581oc
Digital endpoints in clinical trials: emerging themes from a multi-stakeholder Knowledge Exchange event.
Tackney, M. S., Steele, A., Newman, J., Fritzsche, M. -C., Lucivero, F., Khadjesari, Z., . . . Villar, S. S. (2024). Digital endpoints in clinical trials: emerging themes from a multi-stakeholder Knowledge Exchange event.. Trials, 25(1), 521. doi:10.1186/s13063-024-08356-7
320 Development of a generalized glossary for work related to the creation of core outcome sets
Haq, M., Ma, M. S., Ahmed, A., Koza, E., Shi, V. J., Jaure, A., . . . Alam, M. (2024). 320 Development of a generalized glossary for work related to the creation of core outcome sets. Journal of Investigative Dermatology, 144(8), S55. doi:10.1016/j.jid.2024.06.336
A review of Core Outcome Sets (COS) developed for different settings finds there is a subset of outcomes relevant for both research and routine care.
Kearney, A., Williamson, P. R., & Dodd, S. (2024). A review of Core Outcome Sets (COS) developed for different settings finds there is a subset of outcomes relevant for both research and routine care.. Journal of Clinical Epidemiology.
Experiences of core outcome set developers on including stakeholders from low- and middle-income countries: An online survey.
Karumbi, J., Gorst, S., Gathara, D., Young, B., & Williamson, P. (2024). Experiences of core outcome set developers on including stakeholders from low- and middle-income countries: An online survey.. PLOS global public health, 4(6), e0003365. doi:10.1371/journal.pgph.0003365
Core Outcome Sets for Research and Core Outcome Sets for Routine Care – Do They Overlap?’
Kearney, A., Gorst, S., Williamson, P., & Dodd, S. (2024). Core Outcome Sets for Research and Core Outcome Sets for Routine Care – Do They Overlap?’. Poster session presented at the meeting of HTAi 2024. Seville.
Heading in football: a systematic review of descriptors, definitions, and reporting methods used in heading incidence studies.
Peek, K., Ross, A., Andersen, T. E., Meyer, T., Dahlen, S., Georgieva, J., . . . Serner, A. (2024). Heading in football: a systematic review of descriptors, definitions, and reporting methods used in heading incidence studies.. Science & medicine in football, 1-18. doi:10.1080/24733938.2024.2362191
Increasing uptake through collaboration in the development of core outcome sets: Lessons learned at OMERACT 2023.
Shea, B., Pardo, J. P., Grosskleg, S., Beaton, D. E., Conaghan, P., Goettsch, W., . . . Simon, L. S. (2024). Increasing uptake through collaboration in the development of core outcome sets: Lessons learned at OMERACT 2023.. Seminars in arthritis and rheumatism, 66, 152438. doi:10.1016/j.semarthrit.2024.152438
Uptake of core outcome sets in pediatric clinical trials: a protocol
Quantifying the carbon footprint of academic clinical trials: building the evidence base and hotspot identification
Core outcome set developers should consider and specify the level of granularity of outcome domains.
Kottner, J., Beaton, D., Clarke, M., Dodd, S., Kirkham, J., Lange, T., . . . Williamson, P. (2024). Core outcome set developers should consider and specify the level of granularity of outcome domains.. Journal of clinical epidemiology, 169, 111307. doi:10.1016/j.jclinepi.2024.111307
Representation of published core outcome sets in practice guidelines.
Rhodes, S., Dodd, S., Deckert, S., Vasanthan, L., Qiu, R., Rohde, J. F., . . . Williamson, P. R. (2024). Representation of published core outcome sets in practice guidelines.. Journal of clinical epidemiology, 169, 111311. doi:10.1016/j.jclinepi.2024.111311
Study found increasing use of core outcome sets in Cochrane systematic reviews and identified facilitators and barriers.
Saldanha, I. J., Hughes, K. L., Dodd, S., Lasserson, T., Kirkham, J. J., Wu, Y., . . . Williamson, P. R. (2024). Study found increasing use of core outcome sets in Cochrane systematic reviews and identified facilitators and barriers.. Journal of clinical epidemiology, 169, 111277. doi:10.1016/j.jclinepi.2024.111277
Using behavioral science to increase core outcome set use in trials.
Matvienko-Sikar, K., Hussey, S., Mellor, K., Byrne, M., Clarke, M., Kirkham, J. J., . . . Williamson, P. R. (2024). Using behavioral science to increase core outcome set use in trials.. Journal of clinical epidemiology, 168, 111285. doi:10.1016/j.jclinepi.2024.111285
Uptake of core outcome sets by clinical trialists in China: a protocol.
Qiu, R., Fan, X., Wang, W., Clarke, M., Chen, Z., Liu, S., . . . Shang, H. (2024). Uptake of core outcome sets by clinical trialists in China: a protocol.. F1000Research, 12, 1030. doi:10.12688/f1000research.139282.2
The outcomes measured and reported in intracranial meningioma clinical trials: A systematic review.
Millward, C. P., Keshwara, S. M., Armstrong, T. S., Barrington, H., Bell, S., Brodbelt, A. R., . . . EORTC BTG, ICOM, EANO, SNO, RANO-PRO, BNOS, SBNS, BIMS, TBTC, International Brain Tumour Alliance, Brainstrust, and Brain Tumour Foundation of Canada. (2024). The outcomes measured and reported in intracranial meningioma clinical trials: A systematic review.. Neuro-oncology advances, 6(1), vdae030. doi:10.1093/noajnl/vdae030
Core outcome measurement set for research and clinical practice in post-COVID-19 condition (long COVID) in children and young people: an international Delphi consensus study "PC-COS Children".
Seylanova, N., Chernyavskaya, A., Degtyareva, N., Mursalova, A., Ajam, A., Xiao, L., . . . PC-COS Children Study Group. (2024). Core outcome measurement set for research and clinical practice in post-COVID-19 condition (long COVID) in children and young people: an international Delphi consensus study "PC-COS Children".. The European respiratory journal, 63(3), 2301761. doi:10.1183/13993003.01761-2023
Design, recruitment and baseline characteristics of the LENS trial.
LENS Collaborative Group. (2024). Design, recruitment and baseline characteristics of the LENS trial.. Diabetic medicine : a journal of the British Diabetic Association, e15310. doi:10.1111/dme.15310
Understanding implementation of findings from trial method research: a mixed methods study applying implementation frameworks and behaviour change models.
Coffey, T., Williamson, P. R., Gillies, K., & Trials Methodology Research Partnership Working Groups. (2024). Understanding implementation of findings from trial method research: a mixed methods study applying implementation frameworks and behaviour change models.. Trials, 25(1), 139. doi:10.1186/s13063-024-07968-3
The use of healthcare systems data for RCTs
Toader, A. -M., Gamble, C. L., Dodd, S., & Williamson, P. R. (n.d.). The use of healthcare systems data for RCTs. Trials, 25(1). doi:10.1186/s13063-023-07846-4
Using healthcare systems data for outcomes in clinical trials: issues to consider at the design stage.
Toader, A. -M., Campbell, M. K., Quint, J. K., Robling, M., Sydes, M. R., Thorn, J., . . . Williamson, P. (2024). Using healthcare systems data for outcomes in clinical trials: issues to consider at the design stage.. Trials, 25(1), 94. doi:10.1186/s13063-024-07926-z
Quantifying the carbon footprint of clinical trials: guidance development and case studies.
Griffiths, J., Fox, L., Williamson, P. R., & Low Carbon Clinical Trials Group. (2024). Quantifying the carbon footprint of clinical trials: guidance development and case studies.. BMJ open, 14(1), e075755. doi:10.1136/bmjopen-2023-075755
Identification and Assessment of Outcome Measurement Instruments in Cauda Equina Syndrome: A Systematic Review.
Richardson, G. E., Millward, C. P., Mitchell, J. W., Clark, S., Wilby, M., Marson, A. G., . . . Srikandarajah, N. (2024). Identification and Assessment of Outcome Measurement Instruments in Cauda Equina Syndrome: A Systematic Review.. Global spine journal, 21925682241227916. doi:10.1177/21925682241227916
Stakeholders' perspectives on clinical trial acceptability and approach to consent within a limited timeframe: a mixed methods study.
Deja, E., Donohue, C., Semple, M. G., Woolfall, K., & BESS Investigators. (2024). Stakeholders' perspectives on clinical trial acceptability and approach to consent within a limited timeframe: a mixed methods study.. BMJ open, 14(1), e077023. doi:10.1136/bmjopen-2023-077023
The outcomes measured and reported in observational studies of incidental and untreated intracranial meningioma: A systematic review.
Millward, C. P., Islim, A. I., Armstrong, T. S., Barrington, H., Bell, S., Brodbelt, A. R., . . . EORTC BTG, ICOM, EANO, SNO, RANO-PRO, BNOS, SBNS, BIMS, TBTC, International Brain Tumour Alliance, Brainstrust, and Brain Tumour Foundation of Canada . (2024). The outcomes measured and reported in observational studies of incidental and untreated intracranial meningioma: A systematic review.. Neuro-oncology advances, 6(1), vdae042. doi:10.1093/noajnl/vdae042
2023
To adopt or adapt an existing neonatal core outcome set in Kenya: a study protocol.
Karumbi, J., Gathara, D., Young, B., & Williamson, P. (2023). To adopt or adapt an existing neonatal core outcome set in Kenya: a study protocol.. Trials, 24(1), 806. doi:10.1186/s13063-023-07821-z
Opening up ideas: an advent calendar for patient and public engagement in clinical trials research.
Harman, N. L., McGiveron, K., Tudur Smith, C., Williamson, P. R., & Barrington, H. (2023). Opening up ideas: an advent calendar for patient and public engagement in clinical trials research.. Research involvement and engagement, 9(1), 118. doi:10.1186/s40900-023-00530-6
Measuring the success of programmes of care for people living with dementia: a protocol for consensus building with consumers to develop a set of Core Outcome Measures for Improving Care (COM-IC).
Comans, T., Nguyen, K., Gray, L., Flicker, L., Williamson, P., Dodd, S., . . . Kurrle, S. E. (2023). Measuring the success of programmes of care for people living with dementia: a protocol for consensus building with consumers to develop a set of Core Outcome Measures for Improving Care (COM-IC).. BMJ Open, 13(12), e073884. doi:10.1136/bmjopen-2023-073884
Awareness and experiences on core outcome set development and use amongst stakeholders from low- and middle- income countries: An online survey.
Karumbi, J., Gorst, S., Gathara, D., Young, B., & Williamson, P. (2023). Awareness and experiences on core outcome set development and use amongst stakeholders from low- and middle- income countries: An online survey.. PLOS global public health, 3(12), e0002574. doi:10.1371/journal.pgph.0002574
Clinical trials of pneumonia management assess heterogeneous outcomes and measurement instruments.
Mathioudakis, A. G., Fally, M., Hansel, J., Robey, R. C., Haseeb, F., Williams, T., . . . Pneumonia Outcomes Group. (2023). Clinical trials of pneumonia management assess heterogeneous outcomes and measurement instruments.. Journal of clinical epidemiology, 164, 88-95. doi:10.1016/j.jclinepi.2023.10.011
Developing consensus on core outcome sets of domains for acute, the transition from acute to chronic, recurrent/episodic, and chronic pain: results of the INTEGRATE-pain Delphi process.
Bova, G., Domenichiello, A., Letzen, J. E., Rosenberger, D. C., Siddons, A., Kaiser, U., . . . Pogatzki-Zahn, E. M. (2023). Developing consensus on core outcome sets of domains for acute, the transition from acute to chronic, recurrent/episodic, and chronic pain: results of the INTEGRATE-pain Delphi process.. EClinicalMedicine, 66, 102340. doi:10.1016/j.eclinm.2023.102340
Efficacy and safety of ciclosporin versus methotrexate in the treatment of severe atopic dermatitis in children and young people (TREAT): a multicentre parallel group assessor-blinded clinical trial.
Flohr, C., Rosala-Hallas, A., Jones, A. P., Beattie, P., Baron, S., Browne, F., . . . TREAT Trial Investigators. (2023). Efficacy and safety of ciclosporin versus methotrexate in the treatment of severe atopic dermatitis in children and young people (TREAT): a multicentre parallel group assessor-blinded clinical trial.. The British journal of dermatology, 189(6), 674-684. doi:10.1093/bjd/ljad281
NCOG-26. CORE OUTCOME SETS FOR USE IN FUTURE MENINGIOMA CLINICAL STUDIES: RESULTS OF THE COSMIC PROJECT
Millward, C., Islim, A., Keshwara, S., Srikandarajah, N., Brodbelt, A., Marson, A., . . . Jenkinson, M. (2023). NCOG-26. CORE OUTCOME SETS FOR USE IN FUTURE MENINGIOMA CLINICAL STUDIES: RESULTS OF THE COSMIC PROJECT. Neuro-Oncology, 25(Supplement_5), v219. doi:10.1093/neuonc/noad179.0839
Core outcome measurement instruments for use in clinical and research settings for adults with post-COVID-19 condition: an international Delphi consensus study.
Gorst, S. L., Seylanova, N., Dodd, S. R., Harman, N. L., O'Hara, M., Terwee, C. B., . . . PC-COS study group. (2023). Core outcome measurement instruments for use in clinical and research settings for adults with post-COVID-19 condition: an international Delphi consensus study.. The Lancet. Respiratory medicine, S2213-2600(23)00370-3. doi:10.1016/s2213-2600(23)00370-3
The use of healthcare systems data for RCTs
e-Consent in UK academic-led clinical trials: current practice, challenges and the need for more evidence.
Mitchell, E. J., Appelbe, D., Bravery, A., Culliford, L., Evans, H., Farrin, A. J., . . . as part of the e-Consent collaborative group. (2023). e-Consent in UK academic-led clinical trials: current practice, challenges and the need for more evidence.. Trials, 24(1), 657. doi:10.1186/s13063-023-07656-8
Individualised variable-interval risk-based screening in diabetic retinopathy: the ISDR research programme including RCT
Harding, S., Alshukri, A., Appelbe, D., Broadbent, D., Burgess, P., Byrne, P., . . . Williamson, P. (2023). Individualised variable-interval risk-based screening in diabetic retinopathy: the ISDR research programme including RCT.
Timing of Primary Surgery for Cleft Palate.
Gamble, C., Persson, C., Willadsen, E., Albery, L., Soegaard Andersen, H., Zattoni Antoneli, M., . . . TOPS Study Group. (2023). Timing of Primary Surgery for Cleft Palate.. The New England journal of medicine, 389(9), 795-807. doi:10.1056/nejmoa2215162
Selective outcome reporting in randomised controlled trials including participants with stroke or transient ischaemic attack: A systematic review.
Syed, M., Martin, H., Sena, E. S., Williamson, P. R., & Al-Shahi Salman, R. (2023). Selective outcome reporting in randomised controlled trials including participants with stroke or transient ischaemic attack: A systematic review.. European stroke journal, 23969873231194811. doi:10.1177/23969873231194811
A Foundation for Patient-Centered Core Impact Sets: Key Learnings from Past and Existing Approaches.
Perfetto, E. M., Love, T. R., Oehrlein, E. M., Schoch, S. C., Schrandt, S., & National Health Council Patient-Centered Core Impact Set Advisory Committee. (2023). A Foundation for Patient-Centered Core Impact Sets: Key Learnings from Past and Existing Approaches.. The patient, 16(4), 293-300. doi:10.1007/s40271-023-00630-1
A systematic review of studies reporting the development of Core Outcome Sets for use in routine care
Kearney, A., Gargon, E., Mitchell, J., Callaghan, S., Yameen, F., Williamson, P., & Dodd, S. (2023). A systematic review of studies reporting the development of Core Outcome Sets for use in routine care. Journal of Clinical Epidemiology, 158, 34-43. doi:10.1016/j.jclinepi.2023.03.011
Current trends, barriers, and facilitators of use of core outcome sets in Cochrane systematic reviews: Protocol
Saldanha, I., Hughes, K., Dodd, S., Lasserson, T., Kirkham, J., Lucas, S., & Williamson, P. (n.d.). Current trends, barriers, and facilitators of use of core outcome sets in Cochrane systematic reviews: Protocol. F1000Research, 12, 735. doi:10.12688/f1000research.133688.1
Irish funder guidance increased searching for, and uptake of, core outcome sets
Beecher, C., Galvin, S., Cody, A., Williamson, P. R., Hughes, K., Ward, O., . . . Devane, D. (2023). Irish funder guidance increased searching for, and uptake of, core outcome sets. JOURNAL OF CLINICAL EPIDEMIOLOGY, 158, 92-98. doi:10.1016/j.jclinepi.2023.03.019
Patient-reported outcomes for people with diabetes: what and how to measure? A narrative review
Terwee, C. B., Elders, P. J. M., Blom, M. T., Beulens, J. W., Rolandsson, O., Rogge, A. A., . . . Rutters, F. (2023). Patient-reported outcomes for people with diabetes: what and how to measure? A narrative review. DIABETOLOGIA, 66(8), 1357-1377. doi:10.1007/s00125-023-05926-3
Development of core outcome sets for both research and care
Kearney, A., Dodd, S., & Williamson, P. R. (2023). Development of core outcome sets for both research and care. ACTA OBSTETRICIA ET GYNECOLOGICA SCANDINAVICA, 102(7), 960. doi:10.1111/aogs.14586
Patient participation impacts outcome domain selection in core outcome sets for research: an updated systematic review
Dodd, S., Gorst, S. L., Young, A., Lucas, S. W., & Williamson, P. R. (2023). Patient participation impacts outcome domain selection in core outcome sets for research: an updated systematic review. Journal of Clinical Epidemiology. doi:10.1016/j.jclinepi.2023.03.022
Core outcome sets, developed collaboratively with patients, can improve the relevance and comparability of clinical trials
Mathioudakis, A. G., Khaleva, E., Fally, M., Williamson, P. R., Jensen, J. -U., Felton, T. W., . . . Vestbo, J. (2023). Core outcome sets, developed collaboratively with patients, can improve the relevance and comparability of clinical trials. EUROPEAN RESPIRATORY JOURNAL, 61(4). doi:10.1183/13993003.02107-2022
PD16-05 A SYSTEMATIC REVIEW TO EVALUATE PATIENT-REPORTED OUTCOMES MEASURES (PROMS) FOR METASTATIC PROSTATE CANCER ACCORDING TO THE COSMIN METHODOLOGY: A PIONEER WP2 PROJECT
Ratti, M. M., Gandaglia, G., Sisca, E. S., Derevianko, A., Alleva, E., Beyer, K., . . . Briganti, A. (2023). PD16-05 A SYSTEMATIC REVIEW TO EVALUATE PATIENT-REPORTED OUTCOMES MEASURES (PROMS) FOR METASTATIC PROSTATE CANCER ACCORDING TO THE COSMIN METHODOLOGY: A PIONEER WP2 PROJECT. Journal of Urology, 209(Supplement 4). doi:10.1097/ju.0000000000003271.05
A systematic review to evaluate Patient-Reported Outcomes Measures (PROMs) for metastatic prostate cancer according to the COSMIN methodology – A PIONEER wp2 project
Ratti, M. M., Gandaglia, G., Armando, S., Mazzone, E., Scuderi, S., Barletta, F., . . . Briganti, A. (2023). A systematic review to evaluate Patient-Reported Outcomes Measures (PROMs) for metastatic prostate cancer according to the COSMIN methodology – A PIONEER wp2 project. European Urology, 83, S1432-S1433. doi:10.1016/s0302-2838(23)01038-2
A Core Outcome Measurement Set (COMS) for Research and Clinical Practice in Post COVID-19 Condition (Long COVID) in Adults: An International Delphi Consensus Study
A SYSTEMATIC REVIEW TO EVALUATE PATIENT-REPORTED OUTCOMES MEASURES (PROMS) FOR METASTATIC PROSTATE CANCER ACCORDING TO THE COSMIN METHODOLOGY: A PIONEER WP2 PROJECT
Ratti, M. M., Gandaglia, G., Sisca, E. S., Derevianko, A., Alleva, E., Beyer, K., . . . Briganti, A. (2023). A SYSTEMATIC REVIEW TO EVALUATE PATIENT-REPORTED OUTCOMES MEASURES (PROMS) FOR METASTATIC PROSTATE CANCER ACCORDING TO THE COSMIN METHODOLOGY: A PIONEER WP2 PROJECT. In JOURNAL OF UROLOGY Vol. 209 (pp. E491). Retrieved from https://www.webofscience.com/
Current trends, barriers, and facilitators of use of core outcome sets in Cochrane systematic reviews: Protocol
Saldanha, I., Hughes, K., Dodd, S., Lasserson, T., Kirkham, J., Lucas, S., & Williamson, P. (2023). Current trends, barriers, and facilitators of use of core outcome sets in Cochrane systematic reviews: Protocol. doi:10.12688/f1000research.133688.2
Using behavioural science to enhance use of core outcome sets in trials: protocol.
Matvienko-Sikar, K., Byrne, M., Clarke, M., Kirkham, J., Kottner, J., Mellor, K., . . . Williamson, P. (2022). Using behavioural science to enhance use of core outcome sets in trials: protocol.. HRB open research, 5, 23. doi:10.12688/hrbopenres.13510.2
2022
Guidelines for Reporting Outcomes in Trial Protocols The SPIRIT-Outcomes 2022 Extension
Butcher, N. J., Monsour, A., Mew, E. J., Chan, A. -W., Moher, D., Mayo-Wilson, E., . . . Offringa, M. (2022). Guidelines for Reporting Outcomes in Trial Protocols The SPIRIT-Outcomes 2022 Extension. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 328(23), 2345-2356. doi:10.1001/jama.2022.21243
Guidelines for Reporting Outcomes in Trial Reports: The CONSORT-Outcomes 2022 Extension
Butcher, N. J., Monsour, A., Mew, E. J., Chan, A. -W., Moher, D., Mayo-Wilson, E., . . . Offringa, M. (2022). Guidelines for Reporting Outcomes in Trial Reports: The CONSORT-Outcomes 2022 Extension. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 328(22), 2252-2264. doi:10.1001/jama.2022.21022
Query Resolution of Literature Knowledge Graphs using Hybrid Document Embeddings.
Coenen, F., Muhammad, I., Gamble, C., Kearney, A., & Williams, P. (2022). Query Resolution of Literature Knowledge Graphs using Hybrid Document Embeddings..
Protocol for the development of an international Core Outcome Set for treatment trials in adults with epilepsy: the EPilepsy outcome Set for Effectiveness Trials Project (EPSET).
Mitchell, J. W., Noble, A., Baker, G., Batchelor, R., Brigo, F., Christensen, J., . . . Marson, T. (2022). Protocol for the development of an international Core Outcome Set for treatment trials in adults with epilepsy: the EPilepsy outcome Set for Effectiveness Trials Project (EPSET).. Trials, 23(1), 943. doi:10.1186/s13063-022-06729-4
Comparison of published core outcome sets with outcomes recommended in regulatory guidance from the US Food and Drug Administration and European Medicines Agency: cross sectional analysis.
Saldanha, I. J., Dodd, S., Fish, R., Gorst, S. L., Hall, D. A., Jacobsen, P., . . . Williamson, P. R. (2022). Comparison of published core outcome sets with outcomes recommended in regulatory guidance from the US Food and Drug Administration and European Medicines Agency: cross sectional analysis.. BMJ medicine, 1(1), e000233. doi:10.1136/bmjmed-2022-000233
A Systematic Review to Evaluate Patient-Reported Outcome Measures (PROMs) for Metastatic Prostate Cancer According to the COnsensus-Based Standard for the Selection of Health Measurement INstruments (COSMIN) Methodology
Ratti, M. M., Gandaglia, G., Sisca, E. S., Derevianko, A., Alleva, E., Beyer, K., . . . Briganti, A. (2022). A Systematic Review to Evaluate Patient-Reported Outcome Measures (PROMs) for Metastatic Prostate Cancer According to the COnsensus-Based Standard for the Selection of Health Measurement INstruments (COSMIN) Methodology. CANCERS, 14(20). doi:10.3390/cancers14205120
Core outcome sets in medical research.
Kirkham, J. J., & Williamson, P. (2022). Core outcome sets in medical research.. BMJ medicine, 1(1), e000284. doi:10.1136/bmjmed-2022-000284
Review finds core outcome set uptake in new studies and systematic reviews needs improvement
Williamson, P. R., Barrington, H., Blazeby, J. M., Clarke, M., Gargon, E., Gorst, S., . . . Tunis, S. (2022). Review finds core outcome set uptake in new studies and systematic reviews needs improvement. JOURNAL OF CLINICAL EPIDEMIOLOGY, 150, 154-164. doi:10.1016/j.jclinepi.2022.06.016
THE MEASUREMENT AND REPORTING OF OUTCOMES IN CLINICAL STUDIES OF INCIDENTAL AND UNTREATED MENINGIOMA ARE HETEROGENEOUS AND PREVENT KNOWLEDGE PROGRESS: A SYSTEMATIC REVIEW
Millward, C., Islim, A., Keshwara, S., Srikandarajah, N., Brodbelt, A., Marson, A., . . . Jenkinson, M. (2022). THE MEASUREMENT AND REPORTING OF OUTCOMES IN CLINICAL STUDIES OF INCIDENTAL AND UNTREATED MENINGIOMA ARE HETEROGENEOUS AND PREVENT KNOWLEDGE PROGRESS: A SYSTEMATIC REVIEW. In NEURO-ONCOLOGY Vol. 24 (pp. 18-19). Retrieved from https://www.webofscience.com/
THE OUTCOMES MEASURED AND REPORTED IN MENINGIOMA CLINICAL EFFECTIVENESS TRIALS ARE HETEROGENEOUS AND PRECLUDE COMPARATIVE ANALYSIS OF RESULTS: A SYSTEMATIC REVIEW
Millward, C., Islim, A., Keshwara, S., Srikandarajah, N., Brodbelt, A., Marson, A., . . . Jenkinson, M. (2022). THE OUTCOMES MEASURED AND REPORTED IN MENINGIOMA CLINICAL EFFECTIVENESS TRIALS ARE HETEROGENEOUS AND PRECLUDE COMPARATIVE ANALYSIS OF RESULTS: A SYSTEMATIC REVIEW. In NEURO-ONCOLOGY Vol. 24 (pp. 8-9). Retrieved from https://www.webofscience.com/
The Measurement and Reporting of Outcomes in Clinical Studies of Incidental and Untreated Meningioma Are Heterogeneous and Prevent Knowledge Progress: A Systematic Review
The Measurement and Reporting of Outcomes in Clinical Studies of Incidental and Untreated Meningioma Are Heterogeneous and Prevent Knowledge Progress: A Systematic Review (2022). Neuro-oncology, 24(Suppl 4), iv18-iv19.
The Outcomes Measured and Reported in Meningioma Clinical Effectiveness Trials Are Heterogeneous and Preclude Comparative Analysis of Results: A Systematic Review
The Outcomes Measured and Reported in Meningioma Clinical Effectiveness Trials Are Heterogeneous and Preclude Comparative Analysis of Results: A Systematic Review (2022). Neuro-oncology, 24(Suppl 4), iv8-iv9.
IDENTIFYING A CORE OUTCOME SET FOR PULMONARY SARCOIDOSIS RESEARCH - THE FOUNDATION FOR SARCOIDOSIS RESEARCH - SARCOIDOSIS CLINICAL OUTCOMES TASKFORCE (SCOUT)
Harman, N. L., Gorst, S. L., Williamson, P. R., Barnathan, E. S., Baughman, R. P., Judson, M. A., . . . Culver, D. A. (2022). IDENTIFYING A CORE OUTCOME SET FOR PULMONARY SARCOIDOSIS RESEARCH - THE FOUNDATION FOR SARCOIDOSIS RESEARCH - SARCOIDOSIS CLINICAL OUTCOMES TASKFORCE (SCOUT). SARCOIDOSIS VASCULITIS AND DIFFUSE LUNG DISEASES, 39(3). doi:10.36141/svdld.v39i3.12319
Development of a core outcome set for the evaluation of interventions to prevent COVID-19 in care homes (COS-COVID-PCARE Study)
Shepherd, V., Islam, I., Wood, F., Williamson, P. R., Goodman, C., Bath, P. M., . . . Hood, K. (2022). Development of a core outcome set for the evaluation of interventions to prevent COVID-19 in care homes (COS-COVID-PCARE Study). BMC GERIATRICS, 22(1). doi:10.1186/s12877-022-03395-8
Perspectives of patients, family members, health professionals and the public on the impact of COVID-19 on mental health
Gardiner, E., Baumgart, A., Tong, A., Elliott, J. H., Azevedo, L. C., Bersten, A., . . . Craig, J. C. (2022). Perspectives of patients, family members, health professionals and the public on the impact of COVID-19 on mental health. JOURNAL OF MENTAL HEALTH, 31(4), 524-533. doi:10.1080/09638237.2021.2022637
Opportunities and challenges for the development of "core outcome sets" in neuro-oncology
Millward, C. P., Armstrong, T. S., Barrington, H., Brodbelt, A. R., Bulbeck, H., Byrne, A., . . . Jenkinson, M. D. (2022). Opportunities and challenges for the development of "core outcome sets" in neuro-oncology. NEURO-ONCOLOGY, 24(7), 1048-1055. doi:10.1093/neuonc/noac062
A core outcome set for post-COVID-19 condition in adults for use in clinical practice and research: an international Delphi consensus study
Munblit, D., Nicholson, T., Akrami, A., Apfelbacher, C., Chen, J., De Groote, W., . . . Williamson, P. R. (2022). A core outcome set for post-COVID-19 condition in adults for use in clinical practice and research: an international Delphi consensus study. LANCET RESPIRATORY MEDICINE, 10(7), 715-724. doi:10.1016/S2213-2600(22)00169-2
Development of 'Core Outcome Sets' for Meningioma in Clinical Studies (The COSMIC Project): protocol for two systematic literature reviews, eDelphi surveys and online consensus meetings
Millward, C. P., Armstrong, T. S., Barrington, H., Bell, S., Brodbelt, A. R., Bulbeck, H., . . . SNO, E. B. T. G. I. E. (2022). Development of 'Core Outcome Sets' for Meningioma in Clinical Studies (The COSMIC Project): protocol for two systematic literature reviews, eDelphi surveys and online consensus meetings. BMJ OPEN, 12(5). doi:10.1136/bmjopen-2021-057384
ERS statement: a core outcome set for clinical trials evaluating the management of COPD exacerbations
Mathioudakis, A. G., Abroug, F., Agusti, A., Ananth, S., Bakke, P., Bartziokas, K., . . . Jensen, J. -U. (2022). ERS statement: a core outcome set for clinical trials evaluating the management of COPD exacerbations. EUROPEAN RESPIRATORY JOURNAL, 59(5). doi:10.1183/13993003.02006-2021
Updating and Integrating Core Outcome Sets for Localised, Locally Advanced, Metastatic, and Nonmetastatic Castration-resistant Prostate Cancer: An Update from the PIONEER Consortium
Beyer, K., Moris, L., Lardas, M., Omar, M. I., Healey, J., Tripathee, S., . . . Van Hemelrijck, M. (2022). Updating and Integrating Core Outcome Sets for Localised, Locally Advanced, Metastatic, and Nonmetastatic Castration-resistant Prostate Cancer: An Update from the PIONEER Consortium. EUROPEAN UROLOGY, 81(5), 503-514. doi:10.1016/j.eururo.2022.01.042
An international Delphi consensus process to determine a common data element and core outcome set for frailty: FOCUS (The Frailty Outcomes Consensus Project)
Prorok, J. C., Williamson, P. R., Shea, B., Rolfson, D., Manas, L. R., Cesari, M., . . . Muscedere, J. (2022). An international Delphi consensus process to determine a common data element and core outcome set for frailty: FOCUS (The Frailty Outcomes Consensus Project). BMC GERIATRICS, 22(1). doi:10.1186/s12877-022-02993-w
In-depth qualitative interviews identified barriers and facilitators that influenced chief investigators’ use of core outcome sets in randomised controlled trials
Hughes, K. L., Williamson, P. R., & Young, B. (2022). In-depth qualitative interviews identified barriers and facilitators that influenced chief investigators’ use of core outcome sets in randomised controlled trials. Journal of Clinical Epidemiology, 144, 111-120. doi:10.1016/j.jclinepi.2021.12.004
Standardising the Assessment of Patient-reported Outcome Measures in Localised Prostate Cancer. A Systematic Review.
Ratti, M. M., Gandaglia, G., Alleva, E., Leardini, L., Sisca, E. S., Derevianko, A., . . . PIONEER Consortium. (2022). Standardising the Assessment of Patient-reported Outcome Measures in Localised Prostate Cancer. A Systematic Review.. European urology oncology, 5(2), 153-163. doi:10.1016/j.euo.2021.10.004
The British Orthopaedic Surgery Surveillance study: Perthes' disease The epidemiology and two-year outcomes from a prospective cohort in Great Britain
Perry, D. C., Arch, B., Appelbe, D., Francis, P., Craven, J., Monsell, F. P., . . . Knight, M. (2022). The British Orthopaedic Surgery Surveillance study: Perthes' disease The epidemiology and two-year outcomes from a prospective cohort in Great Britain. BONE & JOINT JOURNAL, 104B(4), 510-518. Retrieved from https://www.webofscience.com/
The British Orthopaedic Surgery Surveillance study: slipped capital femoral epiphysis
Perry, D. C., Arch, B., Appelbe, D., Francis, P., Craven, J., Monsell, F. P., . . . Collaborators, B. O. S. S. (2022). The British Orthopaedic Surgery Surveillance study: slipped capital femoral epiphysis. BONE & JOINT JOURNAL, 104B(4), 519-528. doi:10.1302/0301-620X.104B4.BJJ-2021-1709.R1
Position-based Prompting for Health Outcome Generation
Abaho, M., Bollegala, D., Williamson, P., & Dodd, S. (2022). Position-based Prompting for Health Outcome Generation. Retrieved from http://arxiv.org/abs/2204.03489v1
Position-based Prompting for Health Outcome Generation
Using behavioural science to enhance use of core outcome sets in trials: protocol
Matvienko-Sikar, K., Byrne, M., Clarke, M., Kirkham, J., Kottner, J., Mellor, K., . . . Williamson, P. (n.d.). Using behavioural science to enhance use of core outcome sets in trials: protocol. HRB Open Research, 5, 23. doi:10.12688/hrbopenres.13510.1
Enhancing patient and public contribution in health outcome selection during clinical guideline development: an ethnographic study.
Biggane, A. M., Young, B., Williamson, P. R., Whittingham, E., & Cooper, J. (2022). Enhancing patient and public contribution in health outcome selection during clinical guideline development: an ethnographic study.. BMC health services research, 22(1), 361. doi:10.1186/s12913-022-07736-6
Which outcomes should be used in future bronchiolitis trials? Developing a bronchiolitis core outcome set using a systematic review, Delphi survey and a consensus workshop
Rosala-Hallas, A., Jones, A. P., Williamson, P. R., Bedson, E., Compton, V., Fernandes, R. M., . . . McNamara, P. S. (2022). Which outcomes should be used in future bronchiolitis trials? Developing a bronchiolitis core outcome set using a systematic review, Delphi survey and a consensus workshop. BMJ Open, 12(3), e052943. doi:10.1136/bmjopen-2021-052943
Methodology over metrics: Response to Van Calster et al
Bunce, C., Hewison, J., Teare, M. D., Al-Janabi, H., Bonnett, L., Hulme, C., . . . Williamson, P. (2022). Methodology over metrics: Response to Van Calster et al. JOURNAL OF CLINICAL EPIDEMIOLOGY, 143, 254. doi:10.1016/j.jclinepi.2021.11.008
Outcomes assessed in therapeutic randomized controlled trials in hospitalized patients with COVID-19: is the meta Core Outcome Set (meta-COS) adopted?
Fally, M., Mathioudakis, A. G., Digby, J. W., & Williamson, P. R. (2022). Outcomes assessed in therapeutic randomized controlled trials in hospitalized patients with COVID-19: is the meta Core Outcome Set (meta-COS) adopted?. CLINICAL MICROBIOLOGY AND INFECTION, 28(3), 456-457. doi:10.1016/j.cmi.2021.11.017
A pilot study assessing the similarity between core outcome sets and outcomes included in health technology assessments
Cox, P., R. Williamson, P., & Dodd, S. (n.d.). A pilot study assessing the similarity between core outcome sets and outcomes included in health technology assessments. F1000Research, 10, 1084. doi:10.12688/f1000research.73647.2
Assessment of contextualised representations in detecting outcome phrases in clinical trials
Studying the post-COVID-19 condition: research challenges, strategies, and importance of Core Outcome Set development
Munblit, D., Nicholson, T. R., Needham, D. M., Seylanova, N., Parr, C., Chen, J., . . . Williamson, P. R. (2022). Studying the post-COVID-19 condition: research challenges, strategies, and importance of Core Outcome Set development. BMC MEDICINE, 20(1). doi:10.1186/s12916-021-02222-y
Developing an online, searchable database to systematically map and organise current literature on retention research (ORRCA2)
Kearney, A., Ashford, P. -A., Butlin, L., Conway, T., Cragg, W. J., Devane, D., . . . Gamble, C. (2022). Developing an online, searchable database to systematically map and organise current literature on retention research (ORRCA2). CLINICAL TRIALS, 19(1), 71-80. doi:10.1177/17407745211053803
Does Sleep Position Influence Sleep-Disordered Breathing in Infants With Cleft Palate: A Feasibility Study?
Murray, C. S., Walsh, T., Bannister, T., Metryka, A., Davies, K., Lin, Y. L., . . . Bruce, I. (2022). Does Sleep Position Influence Sleep-Disordered Breathing in Infants With Cleft Palate: A Feasibility Study?. CLEFT PALATE-CRANIOFACIAL JOURNAL, 59(2), 254-261. doi:10.1177/10556656211003459
Use of core outcome sets was low in clinical trials published in major medical
Matvienko-Sikar, K., Avery, K., Blazeby, J. M., Devane, D., Dodd, S., Egan, A. M., . . . Williamson, P. R. (2022). Use of core outcome sets was low in clinical trials published in major medical. JOURNAL OF CLINICAL EPIDEMIOLOGY, 142, 19-28. doi:10.1016/j.jclinepi.2021.10.012089
Use of core outcome sets was low in clinical trials published in major medical journals
Matvienko-Sikar, K., Avery, K., Blazeby, J. M., Devane, D., Dodd, S., Egan, A. M., . . . Williamson, P. R. (2022). Use of core outcome sets was low in clinical trials published in major medical journals. Journal of Clinical Epidemiology, 142, 19-28. doi:10.1016/j.jclinepi.2021.10.012
A RANDOMISED CONTROLLED TRIAL PROTOCOL ASSESSING THE EFFECTIVENESS, SAFETY AND COST-EFFECTIVENESS OF METHOTREXATE VERSUS CICLOSPORIN IN THE TREATMENT OF SEVERE ATOPIC ECZEMA IN CHILDREN: THE TREATMENT OF SEVERE ATOPIC ECZEMA TRIAL (TREAT)
Flohr, C., Jones, A., Rosala-Hallas, A., Beat-Tie, P., Baron, S., Browne, F., . . . Irvine, A. D. (2022). A RANDOMISED CONTROLLED TRIAL PROTOCOL ASSESSING THE EFFECTIVENESS, SAFETY AND COST-EFFECTIVENESS OF METHOTREXATE VERSUS CICLOSPORIN IN THE TREATMENT OF SEVERE ATOPIC ECZEMA IN CHILDREN: THE TREATMENT OF SEVERE ATOPIC ECZEMA TRIAL (TREAT). In ACTA DERMATO-VENEREOLOGICA Vol. 102 (pp. 16-17). Retrieved from https://www.webofscience.com/
A pilot study assessing the similarity between core outcome sets and outcomes included in health technology assessments
Cox, P., R. Williamson, P., & Dodd, S. (2022). A pilot study assessing the similarity between core outcome sets and outcomes included in health technology assessments. doi:10.12688/f1000research.73647.3
A randomized controlled trial assessing the effectiveness and safety of ciclosporin vs. methotrexate in the treatment of severe atopic eczema in children and young people: the TREatment of severe Atopic eczema Trial (TREAT)
Flohr, C., Jones, A., Rosala-Hallas, A., Beattie, P., Baron, S., Browne, F., . . . Irvine, A. (2022). A randomized controlled trial assessing the effectiveness and safety of ciclosporin vs. methotrexate in the treatment of severe atopic eczema in children and young people: the TREatment of severe Atopic eczema Trial (TREAT). In BRITISH JOURNAL OF DERMATOLOGY Vol. 187 (pp. 13-14). Retrieved from https://www.webofscience.com/
Clinical outcome assessment for inflammatory bowel disease in routine practice
Razanskaite, V. (2022). Clinical outcome assessment for inflammatory bowel disease in routine practice.
Outcomes in intervention research on snakebite envenomation: a systematic review.
Bhaumik, S., Beri, D., Tyagi, J., Clarke, M., Sharma, S. K., Williamson, P. R., & Jagnoor, J. (2022). Outcomes in intervention research on snakebite envenomation: a systematic review.. F1000Research, 11, 628. doi:10.12688/f1000research.122116.1
Position-based Prompting for Health Outcome Generation
Abaho, M., Bollegala, D., Williamson, P. R., & Dodd, S. (2022). Position-based Prompting for Health Outcome Generation. In PROCEEDINGS OF THE 21ST WORKSHOP ON BIOMEDICAL LANGUAGE PROCESSING (BIONLP 2022) (pp. 26-36). Retrieved from https://www.webofscience.com/
The EPilepsy outcome Set for Effectiveness Trials project (EPSET): Developing a core outcome set for adults with epilepsy
Mitchell, J. W., Noble, A., Williamson, P., & Marson, T. (2022). The EPilepsy outcome Set for Effectiveness Trials project (EPSET): Developing a core outcome set for adults with epilepsy. In EPILEPSIA Vol. 63 (pp. 68). Retrieved from https://www.webofscience.com/
2021
Heterogeneity in outcome assessment for inflammatory bowel disease in routine clinical practice: a mixed-methods study in a sample of English hospitals
Razanskaite, V., Kallis, C., Young, B., Williamson, P. R., & Bodger, K. (2021). Heterogeneity in outcome assessment for inflammatory bowel disease in routine clinical practice: a mixed-methods study in a sample of English hospitals. BMJ OPEN, 11(12). doi:10.1136/bmjopen-2021-056413
A survey of knowledge, perceptions and use of core outcome sets among clinical trialists
Bellucci, C., Hughes, K., Toomey, E., Williamson, P. R., & Matvienko-Sikar, K. (2021). A survey of knowledge, perceptions and use of core outcome sets among clinical trialists. TRIALS, 22(1). doi:10.1186/s13063-021-05891-5
How are trial outcomes prioritised by stakeholders from different regions? Analysis of an international Delphi survey to develop a core outcome set in gastric cancer surgery
Alkhaffaf, B., Metryka, A., Blazeby, J. M., Glenny, A. -M., Williamson, P. R., & Bruce, I. A. (2021). How are trial outcomes prioritised by stakeholders from different regions? Analysis of an international Delphi survey to develop a core outcome set in gastric cancer surgery. PLOS ONE, 16(12). doi:10.1371/journal.pone.0261937
A Core Outcome Set for Nonpharmacological Community-Based Interventions for People Living With Dementia at Home: A Systematic Review of Outcome Measurement Instruments
Harding, A. J. E., Morbey, H., Ahmed, F., Opdebeeck, C., Elvish, R., Leroi, I., . . . Reilly, S. T. (2021). A Core Outcome Set for Nonpharmacological Community-Based Interventions for People Living With Dementia at Home: A Systematic Review of Outcome Measurement Instruments. GERONTOLOGIST, 61(8), E435-E448. doi:10.1093/geront/gnaa071
Detect and Classify - Joint Span Detection and Classification for Health Outcomes
Abaho, M., Bollegala, D., Williamson, P., & Dodd, S. (2021). Detect and Classify - Joint Span Detection and Classification for Health Outcomes. In 2021 CONFERENCE ON EMPIRICAL METHODS IN NATURAL LANGUAGE PROCESSING (EMNLP 2021) (pp. 8709-8721). Retrieved from https://www.webofscience.com/
Pan-Stakeholder Core Outcome Set (COS) Definition for Selected Hematological Malignancies - Results of the Harmony Alliance
Lang, K. M., Bereczky, T., Bolanos, N., Vallejo, A., Plate, A., Morgan, K. E., . . . Bullinger, L. (2021). Pan-Stakeholder Core Outcome Set (COS) Definition for Selected Hematological Malignancies - Results of the Harmony Alliance. In BLOOD Vol. 138. doi:10.1182/blood-2021-145002
BARRIERS AND FACILITATORS TO CLINICAL ACTIVITY INDICES FOR IBD IN ROUTINE PRACTICE: A QUALITATIVE STUDY
Razanskaite, V., Young, B., Williamson, P., & Bodger, K. (2021). BARRIERS AND FACILITATORS TO CLINICAL ACTIVITY INDICES FOR IBD IN ROUTINE PRACTICE: A QUALITATIVE STUDY. In GUT Vol. 70 (pp. A86-A87). doi:10.1136/gutjnl-2021-BSG.158
Lung cancer mortality reduction by LDCT screening: UKLS randomised trial results and international meta-analysis
Field, J. K., Vulkan, D., Davies, M. P. A., Baldwin, D. R., Brain, K. E., Devaraj, A., . . . Duffy, S. W. (2021). Lung cancer mortality reduction by LDCT screening: UKLS randomised trial results and international meta-analysis. LANCET REGIONAL HEALTH-EUROPE, 10. doi:10.1016/j.lanepe.2021.100179
METHODS FOR ASSESSING THE SUCCESS OR FAILURE OF COPD EXACERBATION TREATMENTS IN THERAPEUTIC CLINICAL TRIALS: A META-EPIDEMIOLOGICAL SYSTEMATIC REVIEW
Mathioudakis, A. G., Ananth, S., Bradbury, T., Csoma, B., Romero, G. F., Criner, G., . . . Vestbo, J. (2021). METHODS FOR ASSESSING THE SUCCESS OR FAILURE OF COPD EXACERBATION TREATMENTS IN THERAPEUTIC CLINICAL TRIALS: A META-EPIDEMIOLOGICAL SYSTEMATIC REVIEW. In THORAX Vol. 76 (pp. A65). doi:10.1136/thorax-2021-BTSabstracts.107
Inclusion of participants from low-income and middle-income countries in core outcome sets development: a systematic review
Karumbi, J., Gorst, S. L., Gathara, D., Gargon, E., Young, B., & Williamson, P. R. (2021). Inclusion of participants from low-income and middle-income countries in core outcome sets development: a systematic review. BMJ OPEN, 11(10). doi:10.1136/bmjopen-2021-049981
DEVELOPMENT OF 'CORE OUTCOME SETS' FOR MENINGIOMA IN CLINICAL STUDIES: THE COSMIC PROJECT
Millward, C., Keshwara, S., Islim, A., Srikandarajah, N., Marson, T., Williamson, P., & Jenkinson, M. (2021). DEVELOPMENT OF 'CORE OUTCOME SETS' FOR MENINGIOMA IN CLINICAL STUDIES: THE COSMIC PROJECT. In NEURO-ONCOLOGY Vol. 23 (pp. 22). Retrieved from https://www.webofscience.com/
SCOUT - SARCOIDOSIS OUTCOMES TASKFORCE. A SYSTEMATIC REVIEW OF OUTCOMES TO INFORM THE DEVELOPMENT OF A CORE OUTCOME SET FOR PULMONARY SARCOIDOSIS
Harman, N. L., Gorst, S. L., Williamson, P. R., Barnathan, E. S., Baughman, R. P., Judson, M. A., . . . Culver, D. A. (2021). SCOUT - SARCOIDOSIS OUTCOMES TASKFORCE. A SYSTEMATIC REVIEW OF OUTCOMES TO INFORM THE DEVELOPMENT OF A CORE OUTCOME SET FOR PULMONARY SARCOIDOSIS. SARCOIDOSIS VASCULITIS AND DIFFUSE LUNG DISEASES, 38(3). doi:10.36141/svdld.v38i3.10737
Patient participation in Delphi surveys to develop core outcome sets: systematic review
Barrington, H., Young, B., & Williamson, P. R. (2021). Patient participation in Delphi surveys to develop core outcome sets: systematic review. BMJ OPEN, 11(9). doi:10.1136/bmjopen-2021-051066
An international core outcome set for evaluating interventions to improve informed consent to clinical trials: The ELICIT Study
Gillies, K., Williamson, P. R., Entwistle, V. A., Gardner, H., Treweek, S., & Campbell, M. K. (2021). An international core outcome set for evaluating interventions to improve informed consent to clinical trials: The ELICIT Study. JOURNAL OF CLINICAL EPIDEMIOLOGY, 137, 14-22. doi:10.1016/j.jclinepi.2021.02.020
Representation of published core outcome sets for research in regulatory guidance: protocol
Dodd, S., Fish, R., Gorst, S., Hall, D., Jacobsen, P., Kirkham, J., . . . Williamson, P. (2021). Representation of published core outcome sets for research in regulatory guidance: protocol. doi:10.12688/hrbopenres.13139.3
Patient-reported outcome measures in core outcome sets targeted overlapping domains but through different instruments
Ciani, O., Salcher-Konrad, M., Meregaglia, M., Smith, K., Gorst, S. L., Dodd, S., . . . Fattore, G. (2021). Patient-reported outcome measures in core outcome sets targeted overlapping domains but through different instruments. JOURNAL OF CLINICAL EPIDEMIOLOGY, 136, 26-36. doi:10.1016/j.jclinepi.2021.03.003
Pirfenidone in heart failure with preserved ejection fraction: a randomized phase 2 trial
Lewis, G. A., Dodd, S., Clayton, D., Bedson, E., Eccleson, H., Schelbert, E. B., . . . Miller, C. A. (2021). Pirfenidone in heart failure with preserved ejection fraction: a randomized phase 2 trial. NATURE MEDICINE, 27(8), 1477-+. doi:10.1038/s41591-021-01452-0
Study protocol to develop a core outcome set for thyroid dysfunction to bridge the unmet needs of patient-centred care
Ooi, C. P., Khan, A. H. K. Y., Manaf, R. A., Mustafa, N., Sukor, N., Williamson, P. R., & Kamaruddin, N. A. (2021). Study protocol to develop a core outcome set for thyroid dysfunction to bridge the unmet needs of patient-centred care. BMJ OPEN, 11(7). doi:10.1136/bmjopen-2021-050231
A strategy to reduce the carbon footprint of clinical trials Comment
Adshead, F., Salman, R. A. -S., Aumonier, S., Collins, M., Hood, K., McNamara, C., . . . Williamson, P. R. (2021). A strategy to reduce the carbon footprint of clinical trials Comment. LANCET, 398(10297), 281-282. doi:10.1016/S0140-6736(21)01384-2
Using routinely recorded data in a UK RCT: a comparison to standard prospective data collection methods
Powell, G. A., Bonnett, L. J., Smith, C. T., Hughes, D. A., Williamson, P. R., & Marson, A. G. (2021). Using routinely recorded data in a UK RCT: a comparison to standard prospective data collection methods. TRIALS, 22(1). doi:10.1186/s13063-021-05294-6
Core outcome set for surgical trials in gastric cancer (GASTROS study): international patient and healthcare professional consensus
Alkhaffaf, B., Metryka, A., Blazeby, J. M., Glenny, A. M., Adeyeye, A., Costa, P. M., . . . Bruce, I. A. (2021). Core outcome set for surgical trials in gastric cancer (GASTROS study): international patient and healthcare professional consensus. BRITISH JOURNAL OF SURGERY, 108(10), 1216-1224. doi:10.1093/bjs/znab192
A Survey of Knowledge, Perceptions and Use of Core Outcome Sets among Clinical Trialists
Methods for conducting international Delphi surveys to optimise global participation in core outcome set development: a case study in gastric cancer informed by a comprehensive literature review
Alkhaffaf, B., Blazeby, J. M., Metryka, A., Glenny, A. -M., Adeyeye, A., Costa, P. M., . . . Bruce, I. A. (2021). Methods for conducting international Delphi surveys to optimise global participation in core outcome set development: a case study in gastric cancer informed by a comprehensive literature review. TRIALS, 22(1). doi:10.1186/s13063-021-05338-x
Realising the full potential of data-enabled trials in the UK: a call for action
Sydes, M. R., Barbachano, Y., Bowman, L., Denwood, T., Farmer, A., Garfield-Birkbeck, S., . . . Grp, D. E. T. (2021). Realising the full potential of data-enabled trials in the UK: a call for action. BMJ OPEN, 11(6). doi:10.1136/bmjopen-2020-043906
Harms reported by patients in rheumatology drug trials: a systematic review of randomized trials in the cochrane library from an OMERACT working group
Berthelsen, D. B., Woodworth, T. G., Goel, N., Ioannidis, J. P. A., Tugwell, P., Devoe, D., . . . Christensen, R. (2021). Harms reported by patients in rheumatology drug trials: a systematic review of randomized trials in the cochrane library from an OMERACT working group. SEMINARS IN ARTHRITIS AND RHEUMATISM, 51(3), 607-617. doi:10.1016/j.semarthrit.2020.09.023
The need for core outcome sets in urological cancer research
MacLennan, S., & Williamson, P. R. (2021). The need for core outcome sets in urological cancer research. TRANSLATIONAL ANDROLOGY AND UROLOGY, 10(6), 2832-2835. doi:10.21037/tau-20-1323
More than half of systematic reviews have relevant core outcome sets
Saldanha, I. J., Dodd, S., Gorst, S. L., & Williamson, P. R. (2021). More than half of systematic reviews have relevant core outcome sets. JOURNAL OF CLINICAL EPIDEMIOLOGY, 136, 168-179. doi:10.1016/j.jclinepi.2021.04.019
Representation of published core outcome sets for research in regulatory guidance: protocol
Dodd, S., Fish, R., Gorst, S., Hall, D., Jacobsen, P., Kirkham, J., . . . Williamson, P. R. (n.d.). Representation of published core outcome sets for research in regulatory guidance: protocol. HRB Open Research, 4, 45. doi:10.12688/hrbopenres.13139.1
Surgical microdiscectomy versus transforaminal epidural steroid injection in patients with sciatica secondary to herniated lumbar disc (NERVES): a phase 3, multicentre, open-label, randomised controlled trial and economic evaluation
Wilby, M. J., Best, A., Wood, E., Burnside, G., Bedson, E., Short, H., . . . Williamson, P. R. (2021). Surgical microdiscectomy versus transforaminal epidural steroid injection in patients with sciatica secondary to herniated lumbar disc (NERVES): a phase 3, multicentre, open-label, randomised controlled trial and economic evaluation. LANCET RHEUMATOLOGY, 3(5), E347-E356. doi:10.1016/S2665-9913(21)00036-9
The SANAD II study of the effectiveness and cost-effectiveness of levetiracetam, zonisamide, or lamotrigine for newly diagnosed focal epilepsy: an open-label, non-inferiority, multicentre, phase 4, randomised controlled trial
Marson, A., Burnside, G., Appleton, R., Smith, D., Leach, J. P., Sills, G., . . . Smith, P. E. (2021). The SANAD II study of the effectiveness and cost-effectiveness of levetiracetam, zonisamide, or lamotrigine for newly diagnosed focal epilepsy: an open-label, non-inferiority, multicentre, phase 4, randomised controlled trial. LANCET, 397(10282), 1363-1374. Retrieved from https://www.webofscience.com/
The SANAD II study of the effectiveness and cost-effectiveness of valproate versus levetiracetam for newly diagnosed generalised and unclassifiable epilepsy: an open-label, non-inferiority, multicentre, phase 4, randomised controlled trial
Marson, A., Burnside, G., Appleton, R., Smith, D., Leach, J. P., Sills, G., . . . Smith, P. E. (2021). The SANAD II study of the effectiveness and cost-effectiveness of valproate versus levetiracetam for newly diagnosed generalised and unclassifiable epilepsy: an open-label, non-inferiority, multicentre, phase 4, randomised controlled trial. LANCET, 397(10282), 1375-1386. Retrieved from https://www.webofscience.com/
Core Outcome Measures for Trials in People With Coronavirus Disease 2019: Respiratory Failure, Multiorgan Failure, Shortness of Breath, and Recovery
Tong, A., Baumgart, A., Evangelidis, N., Viecelli, A. K., Carter, S. A., Azevedo, L. C., . . . Craig, J. C. (2021). Core Outcome Measures for Trials in People With Coronavirus Disease 2019: Respiratory Failure, Multiorgan Failure, Shortness of Breath, and Recovery. CRITICAL CARE MEDICINE, 49(3), 503-516. doi:10.1097/CCM.0000000000004817
Onabotulinum toxin-A versus extended release tolterodine in the management of idiopathic overactive bladder in children: A pilot randomised controlled trial (OVERT trial)
Brown, M., Williamson, P. R., Sutton, L., Melling, C., Lewis, M., J.A.Webb, N., & Goyal, A. (2021). Onabotulinum toxin-A versus extended release tolterodine in the management of idiopathic overactive bladder in children: A pilot randomised controlled trial (OVERT trial). JOURNAL OF PEDIATRIC UROLOGY, 17(1). doi:10.1016/j.jpurol.2020.10.012
A randomised controlled trial comparing palate surgery at 6 months versus 12 months of age (the TOPS trial): a statistical analysis plan
Conroy, E. J., Cooper, R., Shaw, W., Persson, C., Willadsen, E., Munro, K. J., . . . Gamble, C. (2021). A randomised controlled trial comparing palate surgery at 6 months versus 12 months of age (the TOPS trial): a statistical analysis plan. TRIALS, 22(1). doi:10.1186/s13063-020-04886-y
Exploring the impact of regional variation on outcome prioritisation in core outcome set development: a case study in the field of gastric cancer surgery
A pilot study assessing the similarity between core outcome sets and outcomes included in health technology assessments.
Cox, P., R Williamson, P., & Dodd, S. (2021). A pilot study assessing the similarity between core outcome sets and outcomes included in health technology assessments.. F1000Research, 10, 1084. doi:10.12688/f1000research.73647.2
A review of the Cochrane COVID-19 Study Register reveals inconsistency in the choice and measurement of SARS-CoV-2 infection outcomes in prevention trials
Dodd, S., Gorst, S., Avery, K., Harman, N., Macefield, R., Williamson, P., . . . COS-COVID-P Steering Committee. (2021). A review of the Cochrane COVID-19 Study Register reveals inconsistency in the choice and measurement of SARS-CoV-2 infection outcomes in prevention trials. doi:10.12688/f1000research.52491.1
A study protocol for the development of a SPIRIT extension for trials conducted using cohorts and routinely collected data (SPIRIT-ROUTINE).
McCarthy, M., O'Keeffe, L., Williamson, P. R., Sydes, M. R., Farrin, A., Lugg-Widger, F., . . . Kearney, P. M. (2021). A study protocol for the development of a SPIRIT extension for trials conducted using cohorts and routinely collected data (SPIRIT-ROUTINE).. HRB open research, 4, 82. doi:10.12688/hrbopenres.13314.1
A systematic review finds core outcome set uptake varies widely across different areas of health.
Hughes, K. L., Clarke, M., & Williamson, P. R. (n.d.). A systematic review finds core outcome set uptake varies widely across different areas of health.. Journal of Clinical Epidemiology. doi:10.1016/j.jclinepi.2020.09.029
Choosing important health outcomes for comparative effectiveness research: 6<SUP>th</SUP> annual update to a systematic review of core outcome sets for research
Gargon, E., Gorst, S. L., Matvienko-Sikar, K., & Williamson, P. R. (2021). Choosing important health outcomes for comparative effectiveness research: 6<SUP>th</SUP> annual update to a systematic review of core outcome sets for research. PLOS ONE, 16(1). doi:10.1371/journal.pone.0244878
Document Ranking for Curated Document Databases Using BERT and Knowledge Graph Embeddings: Introducing GRAB-Rank
Muhammad, I., Bollegala, D., Coenen, F., Gamble, C., Kearney, A., & Williamson, P. (2021). Document Ranking for Curated Document Databases Using BERT and Knowledge Graph Embeddings: Introducing GRAB-Rank. In BIG DATA ANALYTICS AND KNOWLEDGE DISCOVERY (DAWAK 2021) Vol. 12925 (pp. 116-127). doi:10.1007/978-3-030-86534-4_10
HETEROGENEITY IN OUTCOME ASSESSMENT FOR IBD IN ROUTINE PRACTICE: A MIXED-METHODS STUDY OF ENGLISH HOSPITALS
Razanskaite, V., Kallis, C., Young, B., Williamson, P., & Bodger, K. (2021). HETEROGENEITY IN OUTCOME ASSESSMENT FOR IBD IN ROUTINE PRACTICE: A MIXED-METHODS STUDY OF ENGLISH HOSPITALS. In GUT Vol. 70 (pp. A114-A115). doi:10.1136/gutjnl-2020-bsgcampus.215
Intravenous or oral antibiotic treatment in adults and children with cystic fibrosis and <i>Pseudomonas</i> <i>aeruginosa</i> infection: the TORPEDO-CF RCT
Hewer, S. C. L., Smyth, A. R., Brown, M., Jones, A. P., Hickey, H., Kenna, D., . . . Williamson, P. R. (2021). Intravenous or oral antibiotic treatment in adults and children with cystic fibrosis and <i>Pseudomonas</i> <i>aeruginosa</i> infection: the TORPEDO-CF RCT. HEALTH TECHNOLOGY ASSESSMENT, 25(65), 1-+. doi:10.3310/hta25650
Lamotrigine versus levetiracetam or zonisamide for focal epilepsy and valproate versus levetiracetam for generalised and unclassified epilepsy: two SANAD II non-inferiority RCTs Introduction
Marson, A. G., Burnside, G., Appleton, R., Smith, D., Leach, J. P., Sills, G., . . . Smith, P. E. M. (2021). Lamotrigine versus levetiracetam or zonisamide for focal epilepsy and valproate versus levetiracetam for generalised and unclassified epilepsy: two SANAD II non-inferiority RCTs Introduction. HEALTH TECHNOLOGY ASSESSMENT, 25(75), 1-+. doi:10.3310/hta25750
Methods to assess and improve the uptake of core outcome sets
Hughes, K. (2021). Methods to assess and improve the uptake of core outcome sets.
Microdiscectomy compared with transforaminal epidural steroid injection for persistent radicular pain caused by prolapsed intervertebral disc: the NERVES RCT.
Wilby, M. J., Best, A., Wood, E., Burnside, G., Bedson, E., Short, H., . . . Williamson, P. R. (2021). Microdiscectomy compared with transforaminal epidural steroid injection for persistent radicular pain caused by prolapsed intervertebral disc: the NERVES RCT.. Health Technology Assessment, 25(24), 1-86. doi:10.3310/hta25240
Representation of published core outcome sets for research in regulatory guidance: protocol.
Dodd, S., Fish, R., Gorst, S., Hall, D., Jacobsen, P., Kirkham, J., . . . Williamson, P. R. (2021). Representation of published core outcome sets for research in regulatory guidance: protocol.. HRB open research, 4, 45. doi:10.12688/hrbopenres.13139.3
Surgical microdiscectomy vs steroid nerve root injection for sciatica up to 1yr; the nerves trial
Wilby, M., Best, A., Wood, E., Burnside, G., Bedson, E., Short, H., . . . Williamson, P. (2021). Surgical microdiscectomy vs steroid nerve root injection for sciatica up to 1yr; the nerves trial. Brain and Spine, 1, 100013. doi:10.1016/j.bas.2021.100013
Uptake of core outcome sets by clinical trialists publishing in major medical journals: Protocol.
Matvienko-Sikar, K., Avery, K., Blazeby, J., Hughes, K., Jacobsen, P., Kirkham, J., . . . MRC-NIHR TMRP Outcomes Working Group Core Outcome Set Theme. (2020). Uptake of core outcome sets by clinical trialists publishing in major medical journals: Protocol.. HRB open research, 3, 53. doi:10.12688/hrbopenres.13109.2
2020
Outcomes Evaluated in Controlled Clinical Trials on the Management of COVID-19: A Methodological Systematic Review
Mathioudakis, A. G., Fally, M., Hashad, R., Kouta, A., Hadi, A. S., Knight, S. B., . . . Vestbo, J. (2020). Outcomes Evaluated in Controlled Clinical Trials on the Management of COVID-19: A Methodological Systematic Review. LIFE-BASEL, 10(12). doi:10.3390/life10120350
Developing a core outcome set for COVID-19 prevention interventions: the COS COVID-P study
Avery, K., Macefield, R., Gorst, S., Harman, N., Dodd, S., Clarke, M., . . . Comm, C. O. S. C. O. V. I. D. -P. S. S. (2020). Developing a core outcome set for COVID-19 prevention interventions: the COS COVID-P study. COCHRANE DATABASE OF SYSTEMATIC REVIEWS, (12), 15-18. Retrieved from http://gateway.webofknowledge.com/
Can harmonisation of outcomes bridge the translation gap for pre-clinical research? A systematic review of outcomes measured in mouse models of type 2 diabetes
Harman, N., Williamson, P., Sanz-Moreno, A., Papoutsopoulou, S., Lloyd, K. A., Ameen-Ali, K. E., & Macleod, M. (2020). Can harmonisation of outcomes bridge the translation gap for pre-clinical research? A systematic review of outcomes measured in mouse models of type 2 diabetes. Journal of Translational Medicine. doi:10.1186/s12967-020-02649-6
Development of an international Core Outcome Set (COS) for best care for the dying person: study protocol
Zambrano, S. C., Haugen, D. F., van der Heide, A., Tripodoro, V. A., Ellershaw, J., Furst, C. J., . . . Eychmuller, S. (2020). Development of an international Core Outcome Set (COS) for best care for the dying person: study protocol. BMC PALLIATIVE CARE, 19(1). doi:10.1186/s12904-020-00654-6
A core outcome set for pre-eclampsia research: an international consensus development study
Duffy, J. M. N., Cairns, A. E., Richards-Doran, D., van 't Hooft, J., Gale, C., Brown, M., . . . McManus, R. J. (2020). A core outcome set for pre-eclampsia research: an international consensus development study. BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY, 127(12), 1516-1526. doi:10.1111/1471-0528.16319
Core Outcomes Set for Trials in People With Coronavirus Disease 2019
Tong, A., Elliott, J. H., Azevedo, L. C., Baumgart, A., Bersten, A., Cervantes, L., . . . Craig, J. C. (2020). Core Outcomes Set for Trials in People With Coronavirus Disease 2019. CRITICAL CARE MEDICINE, 48(11), 1622-1635. doi:10.1097/CCM.0000000000004585
International Survey to Establish Prioritized Outcomes for Trials in People With Coronavirus Disease 2019
Evangelidis, N., Tong, A., Howell, M., Teixeira-Pinto, A., Elliott, J. H., Azevedo, L. C., . . . Craig, J. C. (2020). International Survey to Establish Prioritized Outcomes for Trials in People With Coronavirus Disease 2019. CRITICAL CARE MEDICINE, 48(11), 1612-1621. doi:10.1097/CCM.0000000000004584
Outcomes evaluated in controlled clinical trials on the management of COVID-19: A methodological systematic review
The worldwide clinical trial research response to the COVID-19 pandemic - the first 100 days.
Janiaud, P., Axfors, C., Van't Hooft, J., Saccilotto, R., Agarwal, A., Appenzeller-Herzog, C., . . . Hemkens, L. G. (2020). The worldwide clinical trial research response to the COVID-19 pandemic - the first 100 days.. F1000Research, 9, 1193. doi:10.12688/f1000research.26707.1
Intravenous versus oral antibiotics for eradication of Pseudomonas aeruginosa in cystic fibrosis (TORPEDO-CF): a randomised controlled trial
Hewer, S. C. L., Smyth, A. R., Brown, M., Jones, A. P., Hickey, H., Kenna, D., . . . Grp, T. O. R. P. E. D. O. -C. F. S. (2020). Intravenous versus oral antibiotics for eradication of Pseudomonas aeruginosa in cystic fibrosis (TORPEDO-CF): a randomised controlled trial. LANCET RESPIRATORY MEDICINE, 8(10), 975-986. doi:10.1016/S2213-2600(20)30331-3
"Vicarious thinking" was a key driver of score change in Delphi surveys for COS development and is facilitated by feedback of results.
Fish, R., MacLennan, S., Alkhaffaf, B., & Williamson, P. R. (2020). "Vicarious thinking" was a key driver of score change in Delphi surveys for COS development and is facilitated by feedback of results.. J Clin Epidemiol. doi:10.1016/j.jclinepi.2020.09.028
Assessing the relevance and uptake of core outcome sets (an agreed minimum collection of outcomes to measure in research studies) in Cochrane systematic reviews: a review
Williamson, P. R., de Ávila Oliveira, R., Clarke, M., Gorst, S. L., Hughes, K., Kirkham, J. J., . . . Schmitt, J. (2020). Assessing the relevance and uptake of core outcome sets (an agreed minimum collection of outcomes to measure in research studies) in Cochrane systematic reviews: a review. BMJ open, 10(9). doi:10.1136/bmjopen-2019-036562
Controversy and Debate Series on Core Outcome Sets. Paper 4: Debate on Paper 1 from the perspective of COMET [Core Outcome Measures in Effectiveness Trials]
Williamson, P. R., Blazeby, J. M., Brookes, S. T., Clarke, M., Terwee, C. B., & Young, B. (2020). Controversy and Debate Series on Core Outcome Sets. Paper 4: Debate on Paper 1 from the perspective of COMET [Core Outcome Measures in Effectiveness Trials]. JOURNAL OF CLINICAL EPIDEMIOLOGY, 125, 222-224. doi:10.1016/j.jclinepi.2020.05.014
Methods used in the selection of instruments for outcomes included in core outcome sets have improved since the publication of the COSMIN/ COMET guideline
Gorst, S. L., Prinsen, C. A. C., Salcher-Konrad, M., Matvienko-Sikar, K., Williamson, P. R., & Terwee, C. B. (2020). Methods used in the selection of instruments for outcomes included in core outcome sets have improved since the publication of the COSMIN/ COMET guideline. JOURNAL OF CLINICAL EPIDEMIOLOGY, 125, 64-75. doi:10.1016/j.jclinepi.2020.05.021
Study protocol for a pragmatic randomised controlled trial comparing the effectiveness and cost-effectiveness of levetiracetam and zonisamide versus standard treatments for epilepsy: a comparison of standard and new antiepileptic drugs (SANAD-II).
Balabanova, S., Taylor, C., Sills, G., Burnside, G., Plumpton, C., Smith, P. E. M., . . . Marson, A. G. (2020). Study protocol for a pragmatic randomised controlled trial comparing the effectiveness and cost-effectiveness of levetiracetam and zonisamide versus standard treatments for epilepsy: a comparison of standard and new antiepileptic drugs (SANAD-II).. BMJ open, 10(8), e040635. doi:10.1136/bmjopen-2020-040635
Uptake of core outcome sets by clinical trialists publishing in major medical journals: Protocol
Matvienko-Sikar, K., Avery, K., Blazeby, J., Hughes, K., Jacobsen, P., Kirkham, J., . . . Williamson, P. R. (n.d.). Uptake of core outcome sets by clinical trialists publishing in major medical journals: Protocol. HRB Open Research, 3, 53. doi:10.12688/hrbopenres.13109.1
A minimal common outcome measure set for COVID-19 clinical research.
WHO Working Group on the Clinical Characterisation and Management of COVID-19 infection. (2020). A minimal common outcome measure set for COVID-19 clinical research.. The Lancet. Infectious diseases, 20(8), e192-e197. doi:10.1016/s1473-3099(20)30483-7
Methodological Challenges in Web-Based Trials: Update and Insights From the Relatives Education and Coping Toolkit Trial
Robinson, H., Appelbe, D., Dodd, S., Flowers, S., Johnson, S., Jones, S. H., . . . Lobban, F. (2020). Methodological Challenges in Web-Based Trials: Update and Insights From the Relatives Education and Coping Toolkit Trial. JMIR Mental Health, 7(7). doi:10.2196/15878
Core outcome set for the management of acute exacerbations of chronic obstructive pulmonary disease: the COS-AECOPD ERS Task Force study protocol
Mathioudakis, A. G., Abroug, F., Agusti, A., Bakke, P., Bartziokas, K., Beghe, B., . . . Jensen, J. -U. (2020). Core outcome set for the management of acute exacerbations of chronic obstructive pulmonary disease: the COS-AECOPD ERS Task Force study protocol. ERJ OPEN RESEARCH, 6(3). doi:10.1183/23120541.00193-2020
Standardising definitions for the pre-eclampsia core outcome set: A consensus development study
Duffy, J. M. N., Cairns, A. E., Magee, L. A., von Dadelszen, P., van 't Hooft, J., Gale, C., . . . McManus, R. J. (2020). Standardising definitions for the pre-eclampsia core outcome set: A consensus development study. Pregnancy Hypertension, 21, 208-217. doi:10.1016/j.preghy.2020.06.005
What is important to people with dementia living at home? A set of core outcome items for use in the evaluation of non-pharmacological community-based health and social care interventions
Reilly, S. T., Harding, A. J. E., Morbey, H., Ahmed, F., Williamson, P. R., Swarbrick, C., . . . Keady, J. (2020). What is important to people with dementia living at home? A set of core outcome items for use in the evaluation of non-pharmacological community-based health and social care interventions. Age and Ageing, 49(4), 664-671. doi:10.1093/ageing/afaa015
Core outcome sets through the healthcare ecosystem: the case of type 2 diabetes updates mellitus
Dodd, S., Harman, N., Taske, N., Minchin, M., Tan, T., & Williamson, P. R. (2020). Core outcome sets through the healthcare ecosystem: the case of type 2 diabetes updates mellitus. TRIALS, 21(1). doi:10.1186/s13063-020-04403-1
A web-based, peer-supported self-management intervention to reduce distress in relatives of people with psychosis or bipolar disorder: the REACT RCT
Lobban, F., Akers, N., Appelbe, D., Capuccinello, R. I., Chapman, L., Collinge, L., . . . Williamson, P. R. (2020). A web-based, peer-supported self-management intervention to reduce distress in relatives of people with psychosis or bipolar disorder: the REACT RCT. HEALTH TECHNOLOGY ASSESSMENT, 24(32), 1-142. doi:10.3310/hta24320
Therapeutic mammaplasty is a safe and effective alternative to mastectomy with or without immediate breast reconstruction
Potter, S., Trickey, A., Rattay, T., O'Connell, R. L., Dave, R., Baker, E., . . . Holcombe, C. (2020). Therapeutic mammaplasty is a safe and effective alternative to mastectomy with or without immediate breast reconstruction. BRITISH JOURNAL OF SURGERY, 107(7), 832-844. doi:10.1002/bjs.11468
Core outcome set measurement for future clinical trials in acute myeloid leukemia: the HARMONY study protocol using a multi-stakeholder consensus-based Delphi process and a final consensus meeting.
Lang, K. M., Harrison, K. L., Williamson, P. R., Huntly, B. J. P., Ossenkoppele, G., Geissler, J., . . . Bullinger, L. (2020). Core outcome set measurement for future clinical trials in acute myeloid leukemia: the HARMONY study protocol using a multi-stakeholder consensus-based Delphi process and a final consensus meeting.. Trials, 21(1). doi:10.1186/s13063-020-04384-1
TAILoR (TelmisArtan and InsuLin Resistance in Human Immunodeficiency Virus [HIV]): An Adaptive-design, Dose-ranging Phase IIb Randomized Trial of Telmisartan for the Reduction of Insulin Resistance in HIV-positive Individuals on Combination Antiretroviral Therapy
Pushpakom, S. P., Kolamunnage-Dona, R., Taylor, C., Foster, T., Spowart, C., Garcia-Finana, M., . . . Pirmohamed, M. (n.d.). TAILoR (TelmisArtan and InsuLin Resistance in Human Immunodeficiency Virus [HIV]): An Adaptive-design, Dose-ranging Phase IIb Randomized Trial of Telmisartan for the Reduction of Insulin Resistance in HIV-positive Individuals on Combination Antiretroviral Therapy. Clinical Infectious Diseases. doi:10.1093/cid/ciz589
Use of routinely collected data in a UK cohort of publicly funded randomised clinical trials [version 1]
McKay, A. J., Jones, A. P., Gamble, C. L., Farmer, A. J., & Williamson, P. R. (2020). Use of routinely collected data in a UK cohort of publicly funded randomised clinical trials [version 1]. F1000Research, 9. doi:10.12688/f1000research.23316.1
A Systematic Review of Core Outcomes for Hypospadias Surgery
Leunbach, T. L., O'Toole, S., Springer, A., Williamson, P. R., & Ahmed, S. F. (2020). A Systematic Review of Core Outcomes for Hypospadias Surgery. SEXUAL DEVELOPMENT, 13(4), 165-170. doi:10.1159/000504973
PNS190 PATIENT-REPORTED OUTCOME MEASURES IN CORE OUTCOME SETS: A CROSS-SECTIONAL STUDY BASED ON THE COMET DATABASE
Ciani, O., Salcher-Konrad, M., Meregaglia, M., Smith, K., Gorst, S., Fattore, G., & Williamson, P. (2020). PNS190 PATIENT-REPORTED OUTCOME MEASURES IN CORE OUTCOME SETS: A CROSS-SECTIONAL STUDY BASED ON THE COMET DATABASE. Value in Health, 23, S319. doi:10.1016/j.jval.2020.04.1185
Su1832 USE OF CLINICAL INFLAMMATORY BOWEL DISEASE ACTIVITY INSTRUMENTS IN REAL-WORLD PRACTICE: A MIXED METHODS EVALUATION
Razanskaite, V., Williamson, P., Young, B., & Bodger, K. (2020). Su1832 USE OF CLINICAL INFLAMMATORY BOWEL DISEASE ACTIVITY INSTRUMENTS IN REAL-WORLD PRACTICE: A MIXED METHODS EVALUATION. Gastroenterology, 158(6). doi:10.1016/s0016-5085(20)32360-x
Usage Metrics of Web-Based Interventions Evaluated in Randomized Controlled Trials: Systematic Review
Koneska, E., Appelbe, D., Williamson, P. R., & Dodd, S. (2020). Usage Metrics of Web-Based Interventions Evaluated in Randomized Controlled Trials: Systematic Review. Journal of Medical Internet Research, 22(4). doi:10.2196/15474
Clinical effectiveness of a web-based peer-supported self-management intervention for relatives of people with psychosis or bipolar (REACT): online, observer-blind, randomised controlled superiority trial
Lobban, F., Akers, N., Appelbe, D., Chapman, L., Collinge, L., Dodd, S., . . . Williamson, P. (2020). Clinical effectiveness of a web-based peer-supported self-management intervention for relatives of people with psychosis or bipolar (REACT): online, observer-blind, randomised controlled superiority trial. BMC psychiatry, 20. doi:10.1186/s12888-020-02545-9
Facilitating International Participation in Core Outcome Set Development: A Proposed Approach for Multi-language Delphi Surveys, a Review of Current Practice and Issues to Consider
A scoping review of core outcome sets and their 'mapping' onto real-world data using prostate cancer as a case study
Meregaglia, M., Ciani, O., Banks, H., Salcher-Konrad, M., Carney, C., Jayawardana, S., . . . Fattore, G. (2020). A scoping review of core outcome sets and their 'mapping' onto real-world data using prostate cancer as a case study. BMC MEDICAL RESEARCH METHODOLOGY, 20(1). doi:10.1186/s12874-020-00928-w
Core outcome set measurement for future clinical trials in acute myeloid leukemia: the HARMONY study protocol using a multi-stakeholder consensus-based Delphi process and a final consensus meeting
Where next for inhaled corticosteroids in childhood asthma?
Sinha, I. P., Dodd, S. R., Grime, C., Hawcutt, D. B., Fernandes, R. M., Roberts, M. R., . . . Williamson, P. R. (2020). Where next for inhaled corticosteroids in childhood asthma?. LANCET RESPIRATORY MEDICINE, 8(4), 345. doi:10.1016/S2213-2600(20)30013-8
P178 Variation in assessment of outcomes for inflammatory bowel disease in routine clinical practice: a mixed-methods study
Razanskaite, V., Williamson, P., Young, B., & Bodger, K. (2020). P178 Variation in assessment of outcomes for inflammatory bowel disease in routine clinical practice: a mixed-methods study. Journal of Crohn's and Colitis, 14(Supplement_1), S227. doi:10.1093/ecco-jcc/jjz203.307
Trial Forge Guidance 2: how to decide if a further Study Within A Trial (SWAT) is needed
Treweek, S., Bevan, S., Bower, P., Briel, M., Campbell, M., Christie, J., . . . Clarke, M. (2020). Trial Forge Guidance 2: how to decide if a further Study Within A Trial (SWAT) is needed. Trials, 21(1). doi:10.1186/s13063-019-3980-5
Cauda Equina Syndrome Core Outcome Set (CESCOS): An international patient and healthcare professional consensus for research studies
Srikandarajah, N., Noble, A., Clark, S., Wilby, M., Freeman, B. J. C., Fehlings, M. G., . . . Marson, T. (n.d.). Cauda Equina Syndrome Core Outcome Set (CESCOS): An international patient and healthcare professional consensus for research studies. PLOS ONE, 15(1), e0225907. doi:10.1371/journal.pone.0225907
Development of the Cauda Equina Syndrome Core Outcome Set for research studies
Srikandarajah, N. (2020). Development of the Cauda Equina Syndrome Core Outcome Set for research studies.
Different corticosteroid induction regimens in children and young people with juvenile idiopathic arthritis: the SIRJIA mixed-methods feasibility study.
Jones, A. P., Clayton, D., Nkhoma, G., Sherratt, F. C., Peak, M., Stones, S. R., . . . Baildam, E. M. (2020). Different corticosteroid induction regimens in children and young people with juvenile idiopathic arthritis: the SIRJIA mixed-methods feasibility study.. Health Technology Assessment, 24(36), 1-152. doi:10.3310/hta24360
Maintaining Curated Document Databases Using a Learning to Rank Model: The ORRCA Experience
Muhammad, I., Bollegala, D., Coenen, F., Gamble, C., Kearney, A., & Williamson, P. (2020). Maintaining Curated Document Databases Using a Learning to Rank Model: The ORRCA Experience. In Unknown Conference (pp. 345-357). Springer International Publishing. doi:10.1007/978-3-030-63799-6_26
Moving Towards Common Data Elements and Core Outcome Measures in Frailty Research
Muscedere, J., Afilalo, J., de Carvalho, I. A., Cesari, M., Clegg, A., Eriksen, H. E., . . . Williamson, P. R. (2020). Moving Towards Common Data Elements and Core Outcome Measures in Frailty Research. JOURNAL OF FRAILTY & AGING, 9(1), 14-22. doi:10.14283/jfa.2019.43
Open Information Extraction for Knowledge Graph Construction
Muhammad, I., Kearney, A., Gamble, C., Coenen, F., & Williamson, P. (2020). Open Information Extraction for Knowledge Graph Construction. In Unknown Conference (pp. 103-113). Springer International Publishing. doi:10.1007/978-3-030-59028-4_10
PATIENT-REPORTED OUTCOME MEASURES IN CORE OUTCOME SETS: A CROSS-SECTIONAL STUDY BASED ON THE COMET DATABASE
Ciani, O., Salcher-Konrad, M., Meregaglia, M., Smith, K., Gorst, S., Fattore, G., & Williamson, P. (2020). PATIENT-REPORTED OUTCOME MEASURES IN CORE OUTCOME SETS: A CROSS-SECTIONAL STUDY BASED ON THE COMET DATABASE. In VALUE IN HEALTH Vol. 23 (pp. S319). Retrieved from https://www.webofscience.com/
Variation in assessment of outcomes for inflammatory bowel disease in routine clinical practice: a mixed-methods study
Razanskaite, V., Williamson, P., Young, B., & Bodger, K. (2020). Variation in assessment of outcomes for inflammatory bowel disease in routine clinical practice: a mixed-methods study. In JOURNAL OF CROHNS & COLITIS Vol. 14 (pp. S227). Retrieved from https://www.webofscience.com/
2019
Selecting Core Outcomes for Randomised Effectiveness Trials in Type 2 Diabetes (SCORE-IT) - a Patient and Healthcare Professional Consensus on a Core Outcome Set for Type 2 Diabetes
Harman, N., Wilding, J., Curry, D., Harris, J., Logue, J., Pemberton, R. J., . . . Team, S. C. O. R. E. -I. T. S. (2019). Selecting Core Outcomes for Randomised Effectiveness Trials in Type 2 Diabetes (SCORE-IT) - a Patient and Healthcare Professional Consensus on a Core Outcome Set for Type 2 Diabetes. BMJ Open Diabetes Research and Care.
Choosing important health outcomes for comparative effectiveness research: 5th annual update to a systematic review of core outcome sets for research.
Gargon, E., Gorst, S. L., & Williamson, P. R. (2019). Choosing important health outcomes for comparative effectiveness research: 5th annual update to a systematic review of core outcome sets for research.. PloS one, 14(12), e0225980. doi:10.1371/journal.pone.0225980
PPI in research: a reflection from early stage researchers
Biggane, A. M., Olsen, M., & Williamson, P. R. (2019). PPI in research: a reflection from early stage researchers. Research Involvement and Engagement, 5(1). doi:10.1186/s40900-019-0170-2
Participating in core outcome set development via Delphi surveys: qualitative interviews provide pointers to inform guidance
Biggane, A. M., Williamson, P. R., Ravaud, P., & Young, B. (2019). Participating in core outcome set development via Delphi surveys: qualitative interviews provide pointers to inform guidance. BMJ OPEN, 9(11). doi:10.1136/bmjopen-2019-032338
Evaluation of an automatic article selection method for timelier updates of the Comet Core Outcome Set database
Norman, C. R., Gargon, E. A., Leeflang, M. M. G., Neveol, A., & Williamson, P. R. (2019). Evaluation of an automatic article selection method for timelier updates of the Comet Core Outcome Set database. Database: the journal of biological databases and curation, 2019. doi:10.1093/database/baz109
Industry funding was associated with increased use of core outcome sets
Kirkham, J. J., Bracken, M., Hind, L., Pennington, K., Clarke, M., & Williamson, P. R. (2019). Industry funding was associated with increased use of core outcome sets. JOURNAL OF CLINICAL EPIDEMIOLOGY, 115, 90-97. doi:10.1016/j.jclinepi.2019.07.007
Trial Forge Guidance 2: How to decide if a further Study Within A Trial (SWAT) is needed
Methodological aspects of the ISDR RCT: Investigating individualised variable interval screening for diabetic retinopathy in a screening population
Cheyne, C. P., Broadbent, D. M., Moitt, T., Howard, L., Howlin, S., Silvera, K., . . . Garcia-Finana, M. (2019). Methodological aspects of the ISDR RCT: Investigating individualised variable interval screening for diabetic retinopathy in a screening population. Poster session presented at the meeting of Unknown Conference. Retrieved from https://www.webofscience.com/
ORRCA and ORRCA2: A large-scale, international, collaboration to map recruitment and retention literature
Kearney, A., Rosala-Hallas, A., Cragg, W. J., Devane, D., Gillies, K., Harman, N. L., . . . Gamble, C. (2019). ORRCA and ORRCA2: A large-scale, international, collaboration to map recruitment and retention literature. In TRIALS Vol. 20. Retrieved from https://www.webofscience.com/
Patient‐reported outcomes
Johnston, B. C., Patrick, D. L., Devji, T., Maxwell, L. J., Bingham, C. O., Beaton, D. E., . . . Guyatt, G. H. (2019). Patient‐reported outcomes. In Unknown Book (pp. 479-492). Wiley. doi:10.1002/9781119536604.ch18
A review of current practice in the design and assessment of internal pilots in UK NIHR clinical trials
Rosala-Hallas, A., Gamble, C., Blazeby, J., & Williamson, P. R. (2019). A review of current practice in the design and assessment of internal pilots in UK NIHR clinical trials. TRIALS, 20(1). doi:10.1186/s13063-019-3669-9
Assessing the impact of a research funder’s recommendation to consider core outcome sets
Hughes, K. L., Kirkham, J., Clarke, M., & Williamson, P. R. (2019). Assessing the impact of a research funder’s recommendation to consider core outcome sets. PLoS One, 14(9). doi:10.1371/journal.pone.0222418
Identifying Possible Outcome Domains from Existing Outcome Measures to Inform an OMERACT Core Domain Set for Safety in Rheumatology Trials
Klokker, L., Berthelsen, D. B., Woodworth, T., Andersen, K. M., Furst, D. E., Devoe, D., . . . Christensen, R. (2019). Identifying Possible Outcome Domains from Existing Outcome Measures to Inform an OMERACT Core Domain Set for Safety in Rheumatology Trials. JOURNAL OF RHEUMATOLOGY, 46(9), 1173-1178. doi:10.3899/jrheum.190196
Methodological Challenges in Web-Based Trials: Update and Insights From the Relatives Education and Coping Toolkit Trial (Preprint)
Robinson, H., Appelbe, D., Dodd, S., Flowers, S., Johnson, S., Jones, S. H., . . . Lobban, F. (2019). Methodological Challenges in Web-Based Trials: Update and Insights From the Relatives Education and Coping Toolkit Trial (Preprint). doi:10.2196/preprints.15878
Pirfenidone in Heart Failure with Preserved Ejection Fraction-Rationale and Design of the PIROUETTE Trial
Lewis, G. A., Schelbert, E. B., Naish, J. H., Bedson, E., Dodd, S., Eccleson, H., . . . Miller, C. A. (2019). Pirfenidone in Heart Failure with Preserved Ejection Fraction-Rationale and Design of the PIROUETTE Trial. CARDIOVASCULAR DRUGS AND THERAPY, 33(4), 461-470. doi:10.1007/s10557-019-06876-y
Improvement was needed in the standards of development for cancer core outcome sets
Gargon, E., Williamson, P. R., Blazeby, J. M., & Kirkham, J. J. (2019). Improvement was needed in the standards of development for cancer core outcome sets. JOURNAL OF CLINICAL EPIDEMIOLOGY, 112, 36-44. doi:10.1016/j.jclinepi.2019.04.006
The OMERACT-OARSI Core Domain Set for Measurement in Clinical Trials of Hip and/or Knee Osteoarthritis
Smith, T. O., Hawker, G. A., Hunter, D. J., March, L. M., Boers, M., Shea, B. J., . . . Conaghan, P. G. (2019). The OMERACT-OARSI Core Domain Set for Measurement in Clinical Trials of Hip and/or Knee Osteoarthritis. JOURNAL OF RHEUMATOLOGY, 46(8), 981-989. doi:10.3899/jrheum.181194
Uptake of the OMERACT-OARSI Hip and Knee Osteoarthritis Core Outcome Set: Review of Randomized Controlled Trials from 1997 to 2017
Smith, T. O., Mansfield, M., Hawker, G. A., Hunter, D. J., March, L. M., Boers, M., . . . Conaghan, P. G. (2019). Uptake of the OMERACT-OARSI Hip and Knee Osteoarthritis Core Outcome Set: Review of Randomized Controlled Trials from 1997 to 2017. JOURNAL OF RHEUMATOLOGY, 46(8), 976-980. doi:10.3899/jrheum.181066
Core outcome set measurement for future clinical trials in acute myeloid leukemia: the HARMONY study protocol using a multi-stakeholder consensus-based Delphi process and a final consensus meeting
Usage Metrics of Web-Based Interventions Evaluated in Randomized Controlled Trials: Systematic Review (Preprint)
Koneska, E., Appelbe, D., Williamson, P. R., & Dodd, S. (2019). Usage Metrics of Web-Based Interventions Evaluated in Randomized Controlled Trials: Systematic Review (Preprint). doi:10.2196/preprints.15474
Timing Of Primary Surgery for cleft palate (TOPS): protocol for a randomised trial of palate surgery at 6 months versus 12 months of age
Shaw, W., Semb, G., Lohmander, A., Persson, C., Willadsen, E., Clayton-Smith, J., . . . Williamson, P. (2019). Timing Of Primary Surgery for cleft palate (TOPS): protocol for a randomised trial of palate surgery at 6 months versus 12 months of age. BMJ OPEN, 9(7). doi:10.1136/bmjopen-2019-029780
Individualised screening for diabetic retinopathy: the ISDR study - rationale, design and methodology for a randomised controlled trial comparing annual and individualised risk-based variable-interval screening
Broadbent, D. M., Sampson, C. J., Wang, A., Howard, L., Williams, A. E., Howlin, S. U., . . . Harding, S. P. (2019). Individualised screening for diabetic retinopathy: the ISDR study - rationale, design and methodology for a randomised controlled trial comparing annual and individualised risk-based variable-interval screening. BMJ OPEN, 9(6). doi:10.1136/bmjopen-2018-025788
VARIATION IN ASSESSMENT OF OUTCOMES FOR IBD IN ROUTINE CLINICAL PRACTICE: AN ETHNOGRAPHIC STUDY
Razanskaite, V., Young, B., Williamson, P., & Bodger, K. (2019). VARIATION IN ASSESSMENT OF OUTCOMES FOR IBD IN ROUTINE CLINICAL PRACTICE: AN ETHNOGRAPHIC STUDY. In GUT Vol. 68 (pp. A91-A92). doi:10.1136/gutjnl-2019-BSGAbstracts.174
WS01-1 Effectiveness of IV compared to oral eradication therapy of Pseudomonas aeruginosa in cystic fibrosis: multicentre randomised controlled trial (TORPEDO-CF)
Langton Hewer, S. C., Smyth, A. R., Jones, A. P., Brown, M., Hickey, H., Williamson, P. R., . . . Ashby, D. (2019). WS01-1 Effectiveness of IV compared to oral eradication therapy of Pseudomonas aeruginosa in cystic fibrosis: multicentre randomised controlled trial (TORPEDO-CF). Journal of Cystic Fibrosis, 18, S1. doi:10.1016/s1569-1993(19)30117-1
Physical Rehabilitation Core Outcomes in Critical Illness: A Modified Delphi Consensus Study to Establish a Core Outcome Set
Connolly, B., Barclay, M., Corner, E., Davies, C., Hart, N., Pattison, N., . . . Blackwood, B. (2019). Physical Rehabilitation Core Outcomes in Critical Illness: A Modified Delphi Consensus Study to Establish a Core Outcome Set. In AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE Vol. 199. Retrieved from https://www.webofscience.com/
Protocol for the development of a core outcome set for cauda equina syndrome: systematic literature review, qualitative interviews, Delphi survey and consensus meeting
Srikandarajah, N., Noble, A. J., Wilby, M., Clark, S., Williamson, P. R., & Marson, A. G. (2019). Protocol for the development of a core outcome set for cauda equina syndrome: systematic literature review, qualitative interviews, Delphi survey and consensus meeting. BMJ OPEN, 9(4). doi:10.1136/bmjopen-2018-024002
The impact of immediate breast reconstruction on the time to delivery of adjuvant therapy: the iBRA-2 study
O'Connell, R. L., Rattay, T., Dave, R. V., Trickey, A., Skillman, J., Barnes, N. L. P., . . . Balata, S. A. (2019). The impact of immediate breast reconstruction on the time to delivery of adjuvant therapy: the iBRA-2 study. BRITISH JOURNAL OF CANCER, 120(9), 883-895. doi:10.1038/s41416-019-0438-1
Adalimumab in combination with methotrexate for refractory uveitis associated with juvenile idiopathic arthritis: a RCT
Ramanan, A. V., Dick, A. D., Jones, A. P., Hughes, D. A., McKay, A., Rosala-Halas, A., . . . Grp, S. Y. C. A. M. O. R. E. S. (2019). Adalimumab in combination with methotrexate for refractory uveitis associated with juvenile idiopathic arthritis: a RCT. HEALTH TECHNOLOGY ASSESSMENT, 23(15), 1-139. doi:10.3310/hta23150
Higher number of items associated with significantly lower response rates in COS Delphi surveys
Gorgon, E., Crew, R., Burnside, G., & Williamson, P. R. (2019). Higher number of items associated with significantly lower response rates in COS Delphi surveys. JOURNAL OF CLINICAL EPIDEMIOLOGY, 108, 110-120. doi:10.1016/j.jclinepi.2018.12.010
TREatment of ATopic eczema (TREAT) Registry Taskforce: an international Delphi exercise to identify a core set of domains and domain items for national atopic eczema photo- and systemic therapy registries
Gerbens, L. A. A., Apfelbacher, C. J., Irvine, A. D., Barbarot, S., de Booij, R. J., Boyce, A. E., . . . Spuls, P. I. (2019). TREatment of ATopic eczema (TREAT) Registry Taskforce: an international Delphi exercise to identify a core set of domains and domain items for national atopic eczema photo- and systemic therapy registries. BRITISH JOURNAL OF DERMATOLOGY, 180(4), 790-801. doi:10.1111/bjd.16714
What is important to people living with dementia?: the "long-list' of outcome items in the development of a core outcome set for use in the evaluation of non-pharmacological community-based health and social care interventions
Harding, A. J. E., Morbey, H., Ahmed, F., Opdebeeck, C., Lasrado, R., Williamson, P. R., . . . Reilly, S. T. (2019). What is important to people living with dementia?: the "long-list' of outcome items in the development of a core outcome set for use in the evaluation of non-pharmacological community-based health and social care interventions. BMC GERIATRICS, 19. doi:10.1186/s12877-019-1103-5
Improving outcome reporting in clinical trial reports and protocols: study protocol for the Instrument for reporting Planned Endpoints in Clinical Trials (InsPECT)
Butcher, N. J., Monsour, A., Mew, E. J., Szatmari, P., Pierro, A., Kelly, L. E., . . . Offringa, M. (2019). Improving outcome reporting in clinical trial reports and protocols: study protocol for the Instrument for reporting Planned Endpoints in Clinical Trials (InsPECT). TRIALS, 20. doi:10.1186/s13063-019-3248-0
Adjustment for treatment changes in epilepsy trials: A comparison of causal methods for time-to-event outcomes
Dodd, S., Williamson, P., & White, I. R. (2019). Adjustment for treatment changes in epilepsy trials: A comparison of causal methods for time-to-event outcomes. STATISTICAL METHODS IN MEDICAL RESEARCH, 28(3), 717-733. doi:10.1177/0962280217735560
Cost-Effectiveness Analysis of Adalimumab for the Treatment of Uveitis Associated with Juvenile Idiopathic Arthritis
Hughes, D. A., Culeddu, G., Plumpton, C. O., Wood, E., Dick, A. D., Jones, A. P., . . . Ramanan, A. V. (2019). Cost-Effectiveness Analysis of Adalimumab for the Treatment of Uveitis Associated with Juvenile Idiopathic Arthritis. Ophthalmology, 126(3), 415-424. doi:10.1016/j.ophtha.2018.09.043
Patient-Focused Drug Development Methods for Benefit-Risk Assessments: A Case Study Using a Discrete Choice Experiment for Antiepileptic Drugs
Holmes, E. A. F., Plumpton, C., Baker, G. A., Jacoby, A., Ring, A., Williamson, P., . . . Hughes, D. A. (2019). Patient-Focused Drug Development Methods for Benefit-Risk Assessments: A Case Study Using a Discrete Choice Experiment for Antiepileptic Drugs. CLINICAL PHARMACOLOGY & THERAPEUTICS, 105(3), 672-683. doi:10.1002/cpt.1231
Incorporating Patients' Perspectives into the Initial Stages of Core Outcome Set Development: A Rapid Review of Qualitative Studies of Type 2 Diabetes
Gorst, S. L., Young, B., Williamson, P. R., Wilding, J. P. H., & Harman, N. (2019). Incorporating Patients' Perspectives into the Initial Stages of Core Outcome Set Development: A Rapid Review of Qualitative Studies of Type 2 Diabetes. BMJ Open Diabetes Research and Care.
Short-term safety outcomes of mastectomy and immediate implant-based breast reconstruction with and without mesh (iBRA): a multicentre, prospective cohort study.
Potter, S., Conroy, E. J., Cutress, R. I., Williamson, P. R., Whisker, L., Thrush, S., . . . Breast Reconstruction Research Collaborative. (2019). Short-term safety outcomes of mastectomy and immediate implant-based breast reconstruction with and without mesh (iBRA): a multicentre, prospective cohort study.. The Lancet. Oncology. doi:10.1016/s1470-2045(18)30781-2
Toward a Core Outcome Set for Head, Neck, and Respiratory Disease in Mucopolysaccharidosis Type II: Systematic Literature Review and Assessment of Heterogeneity in Outcome Reporting
Metryka, A., Brown, N., Mercer, J., Wilkinson, S., Jones, S., Williamson, P., & Bruce, I. (n.d.). Toward a Core Outcome Set for Head, Neck, and Respiratory Disease in Mucopolysaccharidosis Type II: Systematic Literature Review and Assessment of Heterogeneity in Outcome Reporting. Journal of Inborn Errors of Metabolism and Screening, 7. doi:10.1590/2326-4594-iem-18-0016
Involving people living with dementia in research: an accessible modified Delphi survey for core outcome set development
Morbey, H., Harding, A. J. E., Swarbrick, C., Ahmed, F., Elvish, R., Keady, J., . . . Reilly, S. T. (2019). Involving people living with dementia in research: an accessible modified Delphi survey for core outcome set development. TRIALS, 20. doi:10.1186/s13063-018-3069-6
A Pragmatic Phase 4 Randomised Trial to evaluate the Effectiveness of Dapagliflozin compared to Standard of Care in patients with Type 2 Diabetes in Routine Primary Care (DECIDE: NCT02616666)
Williams, R., Beatty, S., Williamson, P., Fenici, P., Dodd, S., Medina, J., & Wilding, J. (2019). A Pragmatic Phase 4 Randomised Trial to evaluate the Effectiveness of Dapagliflozin compared to Standard of Care in patients with Type 2 Diabetes in Routine Primary Care (DECIDE: NCT02616666). In TRIALS Vol. 20. Retrieved from https://www.webofscience.com/
Agreeing outcomes that matter to patients - co-production of an animation to explain core outcome sets
Bagley, H., Gorst, S., Humphreys, R., Craven, R., Vial, C., Williamson, P. R., . . . Gargon, E. (2019). Agreeing outcomes that matter to patients - co-production of an animation to explain core outcome sets. In TRIALS Vol. 20. Retrieved from https://www.webofscience.com/
Assessing attrition in Randomised Control Trials, the identification of attrition risk factors and the challenges of poor reporting: A comparison of reports from 2013 and 2018
Kearney, A., Rosala-Hallas, A., Rainford, N., Blazeby, J. M., Clarke, M., Lane, A. J., . . . Gamble, C. (2019). Assessing attrition in Randomised Control Trials, the identification of attrition risk factors and the challenges of poor reporting: A comparison of reports from 2013 and 2018. In TRIALS Vol. 20. Retrieved from https://www.webofscience.com/
Assessment of outcomes for inflammatory bowel disease in routine clinical practice: an ethnographic study
Razanskaite, V., Williamson, P., Young, B., & Bodger, K. (2019). Assessment of outcomes for inflammatory bowel disease in routine clinical practice: an ethnographic study. In TRIALS Vol. 20. Retrieved from https://www.webofscience.com/
COS and the healthcare research ecosystem
Dodd, S., & Williamson, P. R. (2019). COS and the healthcare research ecosystem. In TRIALS Vol. 20. Retrieved from https://www.webofscience.com/
Core outcome sets for prevention and treatment of postpartum haemorrhage: an international Delphi consensus study
Meher, S., Cuthbert, A., Kirkham, J. J., Williamson, P., Abalos, E., Aflaifel, N., . . . Alfirevic, Z. (2019). Core outcome sets for prevention and treatment of postpartum haemorrhage: an international Delphi consensus study. BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY, 126(1), 83-93. doi:10.1111/1471-0528.15335
Correcting crowdsourced annotations to improve detection of outcome types in evidence based medicine
Abaho, M., Bollegala, D., Williamson, P., & Dodd, S. (2019). Correcting crowdsourced annotations to improve detection of outcome types in evidence based medicine. In CEUR Workshop Proceedings Vol. 2429 (pp. 1-5).
Developing a core outcome set for future pre-eclampsia research: an international consensus development study involving 283 healthcare professionals, 41 researchers and 112 patients from 55 countries
Duffy, J. M. N., Hooft, J. T., Gale, C., Brown, M., Grobman, W., Fitzpatrick, R., . . . McManus, R. J. (2019). Developing a core outcome set for future pre-eclampsia research: an international consensus development study involving 283 healthcare professionals, 41 researchers and 112 patients from 55 countries. In BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY Vol. 126 (pp. 67). Retrieved from https://www.webofscience.com/
Exploring the barriers and facilitators to core outcome set (COS) uptake: assessing the impact of a funder's recommendation to use COS followed by qualitative interviews with clinical trialists
Hughes, K. L., Young, B., Clarke, M., Kirkham, J., & Williamson, P. R. (2019). Exploring the barriers and facilitators to core outcome set (COS) uptake: assessing the impact of a funder's recommendation to use COS followed by qualitative interviews with clinical trialists. In TRIALS Vol. 20. Retrieved from https://www.webofscience.com/
INTRAVENOUS VS ORAL ANTIBIOTICS FOR ERADICATION OF <i>PSEUDOMONAS AERUGINOSA</i> IN CYSTIC FIBROSIS (TORPEDO-CF): A RANDOMISED CONTROLLED TRIAL
Smyth, A. R., Hewer, L. S., Brown, M., Jones, A., Hickey, H., Kenna, D., . . . Williamson, P. (2019). INTRAVENOUS VS ORAL ANTIBIOTICS FOR ERADICATION OF <i>PSEUDOMONAS AERUGINOSA</i> IN CYSTIC FIBROSIS (TORPEDO-CF): A RANDOMISED CONTROLLED TRIAL. In PEDIATRIC PULMONOLOGY Vol. 54 (pp. S302). Retrieved from https://www.webofscience.com/
Internal pilots in clinical trials: Current practice in design and assessment
Rosala-Hallas, A., Gamble, C., Blazeby, J., & Williamson, P. R. (2019). Internal pilots in clinical trials: Current practice in design and assessment. In TRIALS Vol. 20. Retrieved from https://www.webofscience.com/
MOUSE - Mapping OUtcomes measured in pre-clinical Studies against randomised phase 3/4 Effectiveness trials. Do core outcome sets developed for phase3/4 effectiveness trials translate to pre-clinical research?
Harman, N. L., Sanz-Moreno, A., Ameen-Ali, K. E., Papoutsopoulou, S., Lloyd, K., Garcia-Finana, M., . . . Williamson, P. R. (2019). MOUSE - Mapping OUtcomes measured in pre-clinical Studies against randomised phase 3/4 Effectiveness trials. Do core outcome sets developed for phase3/4 effectiveness trials translate to pre-clinical research?. In TRIALS Vol. 20. Retrieved from https://www.webofscience.com/
New methods for an update to a systematic review of core outcome sets for research
Gargon, E., Gorst, S., Norman, C., Leeflang, M., Neveol, A., & Williamson, P. (2019). New methods for an update to a systematic review of core outcome sets for research. In TRIALS Vol. 20. Retrieved from https://www.webofscience.com/
Physical Rehabilitation Core Outcomes in Critical Illness (PRACTICE): a secondary modified thematic analysis characterising reasons for change in rating importance of outcomes for physical rehabilitation trials
Connolly, B., Barclay, M., Corner, E., Davies, C., Hart, N., Pattison, N., . . . Blackwood, B. (2019). Physical Rehabilitation Core Outcomes in Critical Illness (PRACTICE): a secondary modified thematic analysis characterising reasons for change in rating importance of outcomes for physical rehabilitation trials. In TRIALS Vol. 20. Retrieved from https://www.webofscience.com/
Telmisartan to reduce insulin resistance in HIV-positive individuals on combination antiretroviral therapy: the TAILoR dose-ranging Phase II RCT
Pushpakom, S., Kolamunnage-Dona, R., Taylor, C., Foster, T., Spowart, C., Garcia-Finana, M., . . . Pirmohamed, M. (2019). Telmisartan to reduce insulin resistance in HIV-positive individuals on combination antiretroviral therapy: the TAILoR dose-ranging Phase II RCT.
The Sanad II Study Of Effectiveness of Valproate or Levetiracetam in Generalised and Unclassifiable Epilepsy: An Un-Blinded Randomised Controlled Trial
Marson, A., Burnside, G., Appleton, R., Leach, J. P., Sills, G., Tudur-Smith, C., . . . Smith, P. (2019). The Sanad II Study Of Effectiveness of Valproate or Levetiracetam in Generalised and Unclassifiable Epilepsy: An Un-Blinded Randomised Controlled Trial. In EPILEPSIA Vol. 60 (pp. 25). Retrieved from https://www.webofscience.com/
Undertaking trials methodology research using data from clinical trial registries: an exemplar related to core outcome set uptake
Kirkham, J. J., Williamson, P., & Clarke, M. (2019). Undertaking trials methodology research using data from clinical trial registries: an exemplar related to core outcome set uptake. In TRIALS Vol. 20. Retrieved from https://www.webofscience.com/
Use of routinely collected data from electronic health records for outcomes in NIHR HTA trials
Mckay, A. J., Farmer, A. J., Gamble, C., Jones, A. P., & Williamson, P. R. (2019). Use of routinely collected data from electronic health records for outcomes in NIHR HTA trials. In TRIALS Vol. 20. Retrieved from https://www.webofscience.com/
2018
Comprehension of Feedback by Patients within a Delphi Survey
A core outcome set for clinical trials of chemoradiotherapy interventions for anal cancer (CORMAC): a patient and health-care professional consensus
Fish, R., Sanders, C., Adams, R., Brewer, J., Brookes, S. T., DeNardo, J., . . . Renehan, A. G. (2018). A core outcome set for clinical trials of chemoradiotherapy interventions for anal cancer (CORMAC): a patient and health-care professional consensus. LANCET GASTROENTEROLOGY & HEPATOLOGY, 3(12), 865-873. doi:10.1016/S2468-1253(18)30264-4
A framework for prospectively defining progression rules for internal pilot studies monitoring recruitment
Hampson, L. V., Williamson, P. R., Wilby, M. J., & Jaki, T. (2018). A framework for prospectively defining progression rules for internal pilot studies monitoring recruitment. STATISTICAL METHODS IN MEDICAL RESEARCH, 27(12), 3612-3627. doi:10.1177/0962280217708906
A randomized controlled trial protocol assessing the effectiveness, safety and cost-effectiveness of methotrexate vs. ciclosporin in the treatment of severe atopic eczema in children: the TREatment of severe Atopic eczema Trial (TREAT)
Irvine, A. D., Jones, A. P., Beattie, P., Baron, S., Browne, F., Ashoor, F., . . . Flohr, C. (2018). A randomized controlled trial protocol assessing the effectiveness, safety and cost-effectiveness of methotrexate vs. ciclosporin in the treatment of severe atopic eczema in children: the TREatment of severe Atopic eczema Trial (TREAT). BRITISH JOURNAL OF DERMATOLOGY, 179(6), 1297-1306. doi:10.1111/bjd.16717
Abstracts.
Irvine, A. D., Jones, A. P., Beattie, P., Baron, S., Browne, F., Ashoor, F., . . . TREAT Trial Investigators. (2018). Abstracts. . The British journal of dermatology, 179(6), e232-e262. doi:10.1111/bjd.17052
Choosing important health outcomes for comparative effectiveness research: 5th annual update to a systematic review of core outcome sets for research
Gargon, E., Gorst, S. L., & Williamson, P. R. (2019). Choosing important health outcomes for comparative effectiveness research: 5th annual update to a systematic review of core outcome sets for research. PLOS ONE, 14(12). doi:10.1371/journal.pone.0225980
Development of an online resource for recruitment research in clinical trials to organise and map current literature
Kearney, A., Harman, N. L., Rosala-Hallas, A., Beecher, C., Blazeby, J. M., Bower, P., . . . Gamble, C. (2018). Development of an online resource for recruitment research in clinical trials to organise and map current literature. CLINICAL TRIALS, 15(6), 533-542. doi:10.1177/1740774518796156
Non-invasive ventilation for the management of children with bronchiolitis (NOVEMBR): a feasibility study and core outcome set development protocol
van Miert, C., Fernandes, R. M., Eccleson, H., Bedson, E., Lane, S., Peak, M., . . . McNamara, P. S. (2018). Non-invasive ventilation for the management of children with bronchiolitis (NOVEMBR): a feasibility study and core outcome set development protocol. TRIALS, 19. doi:10.1186/s13063-018-2969-9
Interventions for helping people recognise early signs of recurrence in depression
Morriss, R. K., Bolton, C. A., McCarthy, J. P., Marshall, M., Williamson, P. R., & Jones, A. P. (n.d.). Interventions for helping people recognise early signs of recurrence in depression. Cochrane Database of Systematic Reviews. doi:10.1002/14651858.cd004855.pub2
Trial Forge Guidance 2: How to decide if a further Study Within A Trial (SWAT) is needed
Reporting of outcomes in gastric cancer surgery trials: a systematic review
Alkhaffaf, B., Blazeby, J. M., Williamson, P. R., Bruce, I. A., & Glenny, A. -M. (2018). Reporting of outcomes in gastric cancer surgery trials: a systematic review. BMJ OPEN, 8(10). doi:10.1136/bmjopen-2018-021796
Development of a standardised set of metrics for monitoring site performance in multicentre randomised trials: a Delphi study
Whitham, D., Turzanski, J., Bradshaw, L., Clarke, M., Culliford, L., Duley, L., . . . Montgomery, A. A. (2018). Development of a standardised set of metrics for monitoring site performance in multicentre randomised trials: a Delphi study. TRIALS, 19. doi:10.1186/s13063-018-2940-9
Reducing attrition within clinical trials: The communication of retention and withdrawal within patient information leaflets
Kearney, A., Rosala-Hallas, A., Bacon, N., Daykin, A., Shaw, A. R. G., Lane, A. J., . . . Gamble, C. (2018). Reducing attrition within clinical trials: The communication of retention and withdrawal within patient information leaflets. PLOS ONE, 13(10). doi:10.1371/journal.pone.0204886
Outcome reporting bias in trials: a methodological approach for assessment and adjustment in systematic reviews
Kirkham, J. J., Altman, D., Chan, A. -W., Gamble, C. L., Dwan, K. M., & Williamson, P. (2018). Outcome reporting bias in trials: a methodological approach for assessment and adjustment in systematic reviews. BMJ: British Medical Journal, 2018(362). doi:10.1136/bmj.k3802
Nerve root block versus surgery (NERVES) for the treatment of radicular pain secondary to a prolapsed intervertebral disc herniation: study protocol for a multi-centre randomised controlled trial
Wilby, M. J., Hopkins, C., Bedson, E., Howlin, S., Burnside, G., Conroy, E. J., . . . Williamson, P. (2018). Nerve root block versus surgery (NERVES) for the treatment of radicular pain secondary to a prolapsed intervertebral disc herniation: study protocol for a multi-centre randomised controlled trial. TRIALS, 19. doi:10.1186/s13063-018-2677-5
Outcomes Reported After Surgery for Cauda Equina Syndrome: A Systematic Literature Review.
Srikandarajah, N., Wilby, M., Clark, S., Noble, A., Williamson, P., & Marson, T. (2018). Outcomes Reported After Surgery for Cauda Equina Syndrome: A Systematic Literature Review.. Spine, 43(17), E1005-E1013. doi:10.1097/brs.0000000000002605
Survey indicated that core outcome set development is increasingly including patients, being conducted internationally and using Delphi surveys (vol 19, 113, 2018)
Biggane, A. M., Brading, L., Ravaud, P., Young, B., & Williamson, P. R. (2018). Survey indicated that core outcome set development is increasingly including patients, being conducted internationally and using Delphi surveys (vol 19, 113, 2018). TRIALS, 19. doi:10.1186/s13063-018-2595-6
Selecting Core Outcomes for Randomised Effectiveness trials In Type 2 Diabetes (SCORE-IT): study protocol for the development of a core outcome set
Harman, N. L., Wilding, J., Curry, D., Harris, J., Logue, J., Pemberton, R. J., . . . Williamson, P. R. (2018). Selecting Core Outcomes for Randomised Effectiveness trials In Type 2 Diabetes (SCORE-IT): study protocol for the development of a core outcome set. TRIALS, 19. doi:10.1186/s13063-018-2805-2
Inadequate safety reporting in pre-eclampsia trials: a systematic evaluation
Duffy, J. M. N., Hirsch, M., Pealing, L., Showell, M., Khan, K. S., Ziebland, S., & McManus, R. J. (2018). Inadequate safety reporting in pre-eclampsia trials: a systematic evaluation. BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY, 125(7), 795-803. doi:10.1111/1471-0528.14969
Time-dependent efficacy of longitudinal biomarker for clinical endpoint
Kolamunnage-Dona, R., & Williamson, P. R. (2018). Time-dependent efficacy of longitudinal biomarker for clinical endpoint. Statistical Methods in Medical Research, 27(6), 1909-1924. doi:10.1177/0962280216673084
Physical Rehabilitation Core Outcomes In Critical illness (PRACTICE): protocol for development of a core outcome set
Connolly, B., Denehy, L., Hart, N., Pattison, N., Williamson, P., & Blackwood, B. (2018). Physical Rehabilitation Core Outcomes In Critical illness (PRACTICE): protocol for development of a core outcome set. TRIALS, 19. doi:10.1186/s13063-018-2678-4
Adherence to best practice consensus guidelines for implant-based breast reconstruction: Results from the iBRA national practice questionnaire survey
Mylvaganam, S., Conroy, E. J., Williamson, P. R., Barnes, N. L. P., Cutress, R. I., Gardiner, M. D., . . . Holcombe, C. (2018). Adherence to best practice consensus guidelines for implant-based breast reconstruction: Results from the iBRA national practice questionnaire survey. EJSO, 44(5), 708-716. doi:10.1016/j.ejso.2018.01.098
CLINICAL CORE OUTCOMES SETS IN REAL WORLD DATA
Ciani, O., Meregaglia, M., Jayawardana, S., Carney, C., Salcher, M., & Williamson, P. (2018). CLINICAL CORE OUTCOMES SETS IN REAL WORLD DATA. In VALUE IN HEALTH Vol. 21 (pp. S112). doi:10.1016/j.jval.2018.04.761
Systematic review of outcome measures following chemoradiotherapy for the treatment of anal cancer (CORMAC)
Fish, R., Sanders, C., Ryan, N., Van der Veer, S., Renehan, A. G., & Williamson, P. R. (2018). Systematic review of outcome measures following chemoradiotherapy for the treatment of anal cancer (CORMAC). COLORECTAL DISEASE, 20(5), 371-382. doi:10.1111/codi.14103
Developing a core outcome set for people living with dementia at home in their neighbourhoods and communities: study protocol for use in the evaluation of non-pharmacological community-based health and social care interventions
Harding, A. J. E., Morbey, H., Ahmed, F., Opdebeeck, C., Wang, Y. -Y., Williamson, P., . . . Reilly, S. (2018). Developing a core outcome set for people living with dementia at home in their neighbourhoods and communities: study protocol for use in the evaluation of non-pharmacological community-based health and social care interventions. TRIALS, 19. doi:10.1186/s13063-018-2584-9
A taxonomy has been developed for outcomes in medical research to help improve knowledge discovery
Dodd, S., Clarke, M., Becker, L., Mavergames, C., Fish, R., & Williamson, P. R. (2018). A taxonomy has been developed for outcomes in medical research to help improve knowledge discovery. Journal of Clinical Epidemiology, 96, 84-93. doi:10.1016/j.jclinepi.2017.12.020
Quality Measurement Recommendations Relevant to Clinical Guidelines in Germany and the United Kingdom: (What) Can We Learn From Each Other?
Petzold, T., Deckert, S., Williamson, P. R., & Schmitt, J. (2018). Quality Measurement Recommendations Relevant to Clinical Guidelines in Germany and the United Kingdom: (What) Can We Learn From Each Other?. INQUIRY-THE JOURNAL OF HEALTH CARE ORGANIZATION PROVISION AND FINANCING, 55. doi:10.1177/0046958018761495
2017 EULAR recommendations for a core data set to support observational research and clinical care in rheumatoid arthritis
Radner, H., Chatzidionysiou, K., Nikiphorou, E., Gossec, L., Hyrich, K. L., Zabalan, C., . . . Askling, J. (2018). 2017 EULAR recommendations for a core data set to support observational research and clinical care in rheumatoid arthritis. ANNALS OF THE RHEUMATIC DISEASES, 77(4), 476-479. doi:10.1136/annrheumdis-2017-212256
Are the priorities of patients & researchers aligned in the reporting of outcomes in gastric cancer surgery trials?
Alkhaffaf, B., Bruce, I., Glenny, A. -M., Williamson, P., Blazeby, J., & Morris, R. (2018). Are the priorities of patients & researchers aligned in the reporting of outcomes in gastric cancer surgery trials?. European Journal of Surgical Oncology, 44, S27. doi:10.1016/j.ejso.2018.01.541
Identifying trial recruitment uncertainties using a James Lind Alliance Priority Setting Partnership - the PRioRiTy (Prioritising Recruitment in Randomised Trials) study
Healy, P., Galvin, S., Williamson, P. R., Treweek, S., Whiting, C., Maeso, B., . . . Devane, D. (2018). Identifying trial recruitment uncertainties using a James Lind Alliance Priority Setting Partnership - the PRioRiTy (Prioritising Recruitment in Randomised Trials) study. Trials, 19. doi:10.1186/s13063-018-2544-4
Trial Forge Guidance 1: what is a Study Within A Trial (SWAT)?
Treweek, S., Bevan, S., Bower, P., Campbell, M., Christie, J., Clarke, M., . . . Williamson, P. R. (2018). Trial Forge Guidance 1: what is a Study Within A Trial (SWAT)?. TRIALS, 19. doi:10.1186/s13063-018-2535-5
Survey indicated that core outcome set development is increasingly including patients, being conducted internationally and using Delphi surveys
Biggane, A. M., Brading, L., Ravaud, P., Young, B., & Williamson, P. R. (2018). Survey indicated that core outcome set development is increasingly including patients, being conducted internationally and using Delphi surveys. TRIALS, 19. doi:10.1186/s13063-018-2493-y
Global health trials methodological research agenda: results from a priority setting exercise
Rosala-Hallas, A., Bhangu, A., Blazeby, J., Bowman, L., Clarke, M., Lang, T., . . . Williamson, P. R. (2018). Global health trials methodological research agenda: results from a priority setting exercise. TRIALS, 19. doi:10.1186/s13063-018-2440-y
Choosing important health outcomes for comparative effectiveness research: An updated systematic review and involvement of low and middle income countries
Davis, K., Gorst, S. L., Harman, N., Smith, V., Gargon, E., Altman, D. G., . . . Williamson, P. R. (2018). Choosing important health outcomes for comparative effectiveness research: An updated systematic review and involvement of low and middle income countries. PLOS ONE, 13(2). doi:10.1371/journal.pone.0190695
Development of a consensus core dataset in juvenile dermatomyositis for clinical use to inform research.
McCann, L. J., Pilkington, C. A., Huber, A. M., Ravelli, A., Appelbe, D., Kirkham, J. J., . . . Beresford, M. W. (2018). Development of a consensus core dataset in juvenile dermatomyositis for clinical use to inform research.. Annals of the rheumatic diseases, 77(2), 241-250. doi:10.1136/annrheumdis-2017-212141
A Systematic Review of Reported Outcomes for Hypospadias
Leunbach, T. L., O'Toole, S., Springer, A., Williamson, P., & Ahmed, S. F. (2018). A Systematic Review of Reported Outcomes for Hypospadias. In HORMONE RESEARCH IN PAEDIATRICS Vol. 90 (pp. 564-565). Retrieved from https://www.webofscience.com/
A randomized trial comparing three Delphi feedback strategies found no evidence of a difference in a setting with high initial agreement
MacLennan, S., Kirkham, J., Lam, T. B. L., & Williamson, P. R. (2018). A randomized trial comparing three Delphi feedback strategies found no evidence of a difference in a setting with high initial agreement. JOURNAL OF CLINICAL EPIDEMIOLOGY, 93, 1-8. doi:10.1016/j.jclinepi.2017.09.024
An assessment of the use of routinely recorded data in the UK in a randomised controlled trial
Powell, G. A. (2018). An assessment of the use of routinely recorded data in the UK in a randomised controlled trial.
TORPEDO-CF - TRIAL OF OPTIMAL THERAPY FOR <i>PSEUDOMONAS</i> ERADICATION IN CYSTIC FIBROSIS
Hewer, L. S., Smyth, A. R., Jones, A., & Williamson, P. (2018). TORPEDO-CF - TRIAL OF OPTIMAL THERAPY FOR <i>PSEUDOMONAS</i> ERADICATION IN CYSTIC FIBROSIS. In PEDIATRIC PULMONOLOGY Vol. 53 (pp. 294). Retrieved from https://www.webofscience.com/
The Omeract-Oarsi Core Set of Outcome Domains to Measure in Clinical Trials for People with Hip and/or Knee Osteoarthritis
Smith, T. O., Hawker, G., Hunter, D. J., March, L., Shea, B., Christensen, R., . . . Conaghan, P. G. (2018). The Omeract-Oarsi Core Set of Outcome Domains to Measure in Clinical Trials for People with Hip and/or Knee Osteoarthritis. In ARTHRITIS & RHEUMATOLOGY Vol. 70. Retrieved from https://www.webofscience.com/
Treatment of Atopic Dermatitis (TREAT) Registry Taskforce: an international exercise to harmonize data collection for national atopic eczema registries
Gerbens, L. A. A., Vermeulen, F. M., Apfelbacher, C. J., Irvine, A. D., Arents, B. W. M., Barbarot, S., . . . Spuls, P. I. (2018). Treatment of Atopic Dermatitis (TREAT) Registry Taskforce: an international exercise to harmonize data collection for national atopic eczema registries. In BRITISH JOURNAL OF DERMATOLOGY Vol. 179 (pp. E18-E19). Retrieved from https://www.webofscience.com/
2017
Guidelines for the content of statistical analysis plans in clinical trials
Gamble, C. L., Krishan, A., Stocken, D., Lewis, S., Juszczak, E., Dore, C., . . . Loder, E. (2017). Guidelines for the content of statistical analysis plans in clinical trials. JAMA: Journal of the American Medical Association, 318(23), 2337-2343. doi:10.1001/jama.2017.18556
SCORE-IT (Selecting Core Outcomes for Randomised Effectiveness trials In Type 2 diabetes): a systematic review of registered trials
Harman, N. L., James, R., Wilding, J., & Williamson, P. R. (2017). SCORE-IT (Selecting Core Outcomes for Randomised Effectiveness trials In Type 2 diabetes): a systematic review of registered trials. TRIALS, 18. doi:10.1186/s13063-017-2317-5
A systematic review of primary outcomes and outcome measure reporting in randomized trials evaluating treatments for pre-eclampsia
Duffy, J. M. N., Hirsch, M., Gale, C., Pealing, L., Kawsar, A., Showell, M., . . . McManus, R. J. (2017). A systematic review of primary outcomes and outcome measure reporting in randomized trials evaluating treatments for pre-eclampsia. INTERNATIONAL JOURNAL OF GYNECOLOGY & OBSTETRICS, 139(3), 262-267. doi:10.1002/ijgo.12298
Developing an OMERACT Core Outcome Set for Assessing Safety Components in Rheumatology Trials: The OMERACT Safety Working Group
Klokker, L., Tugwell, P., Furst, D. E., Devoe, D., Williamson, P., Terwee, C. B., . . . Christensen, R. (2017). Developing an OMERACT Core Outcome Set for Assessing Safety Components in Rheumatology Trials: The OMERACT Safety Working Group. JOURNAL OF RHEUMATOLOGY, 44(12), 1916-1919. doi:10.3899/jrheum.161105
USING ROUTINELY RECORDED DATA IN A CLINICAL TRIAL
Powell, G., Bonnett, L., Tudur-Smith, C., Hughes, D., Williamson, P., & Marson, T. (2017). USING ROUTINELY RECORDED DATA IN A CLINICAL TRIAL. In JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY Vol. 88 (pp. A75). doi:10.1136/jnnp-2017-ABN.261
Core Health Outcomes In Childhood Epilepsy (CHOICE): protocol for the selection of a core outcome set
Morris, C., Dunkley, C., Gibbon, F. M., Currier, J., Roberts, D., Rogers, M., . . . Pal, D. K. (2017). Core Health Outcomes In Childhood Epilepsy (CHOICE): protocol for the selection of a core outcome set. TRIALS, 18. doi:10.1186/s13063-017-2323-7
Core outcome research measures in anal cancer (CORMAC): protocol for systematic review, qualitative interviews and Delphi survey to develop a core outcome set in anal cancer
Fish, R., Sanders, C., Williamson, P. R., & Renehan, A. G. (2017). Core outcome research measures in anal cancer (CORMAC): protocol for systematic review, qualitative interviews and Delphi survey to develop a core outcome set in anal cancer. BMJ OPEN, 7(11). doi:10.1136/bmjopen-2017-018726
Core Outcome Set-STAndards for Development: The COS-STAD recommendations
Kirkham, J. J., Davis, K., Altman, D. G., Blazeby, J. M., Clarke, M., Tunis, S., & Williamson, P. (2017). Core Outcome Set-STAndards for Development: The COS-STAD recommendations. PLoS Medicine, 14(11). doi:10.1371/journal.pmed.1002447
Priorities for methodological research on patient and public involvement in clinical trials: A modified Delphi process
Kearney, A., Williamson, P., Young, B., Gamble, C., Bagley, H., Denegri, S., . . . woolfall, K. (2017). Priorities for methodological research on patient and public involvement in clinical trials: A modified Delphi process. Health Expectations, 20(6), 1401-1410. doi:10.1111/hex.12583
Model-based sensitivity analysis for outcome reporting bias in the meta analysis of benefit and harm outcomes
Copas, J., Marson, A., Williamson, P., & Kirkham, J. J. (2017). Model-based sensitivity analysis for outcome reporting bias in the meta analysis of benefit and harm outcomes. Statistical Methods in Medical Research. doi:10.1177/0962280217738546
6th Meeting of the COMET Initiative (VI), Amsterdam, November 10-11 2016.
Davis, K., & Williamson, P. (2017). 6th Meeting of the COMET Initiative (VI), Amsterdam, November 10-11 2016.. Journal of evidence-based medicine, 10 Suppl 1, 5-40. doi:10.1111/jebm.12260
A core outcome set for localised prostate cancer effectiveness trials
MacLennan, S., Williamson, P. R., Bekema, H., Campbell, M., Ramsay, C., N'Dow, J., . . . Lam, T. (2017). A core outcome set for localised prostate cancer effectiveness trials. BJU INTERNATIONAL, 120(5B), E64-E79. doi:10.1111/bju.13854
Are the priorities of patients & researchers aligned in the reporting of outcomes in gastric cancer surgery trials?
Alkhaffaf, B., Bruce, I., Glenny, A. -M., Williamson, P., Blazeby, J., & Morris, R. (2017). Are the priorities of patients & researchers aligned in the reporting of outcomes in gastric cancer surgery trials?. European Journal of Surgical Oncology, 43(11), 2225. doi:10.1016/j.ejso.2017.10.143
Outcome reporting across randomised controlled trials evaluating therapeutic interventions for pre-eclampsia
Duffy, J. M. N., Hirsch, M., Kawsar, A., Gale, C., Pealing, L., Plana, M. N., . . . McManus, R. J. (2017). Outcome reporting across randomised controlled trials evaluating therapeutic interventions for pre-eclampsia. BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY, 124(12), 1829-1839. doi:10.1111/1471-0528.14702
Outcomes After Surgery for Patients with Cauda Equina Syndrome: A Systematic Literature Review
Srikandarajah, N., Clark, S., Wilby, M., Noble, A., Williamson, P., & Marson, T. (2017). Outcomes After Surgery for Patients with Cauda Equina Syndrome: A Systematic Literature Review. International Journal of Surgery, 47, S61. doi:10.1016/j.ijsu.2017.08.317
A framework for the design, conduct and interpretation of randomised controlled trials in the presence of treatment changes
Dodd, S., White, I. R., & Williamson, P. (2017). A framework for the design, conduct and interpretation of randomised controlled trials in the presence of treatment changes. Trials, 18. doi:10.1186/s13063-017-2240-9
Variation in the provision and practice of implant-based breast reconstruction in the UK: Results from the iBRA national practice questionnaire
Mylvaganam, S., Conroy, E., Williamson, P. R., Barnes, N. L. P., Cutress, R. I., Gardiner, M. D., . . . Holcombe, C. (2017). Variation in the provision and practice of implant-based breast reconstruction in the UK: Results from the iBRA national practice questionnaire. BREAST, 35, 182-190. doi:10.1016/j.breast.2017.07.016
Core outcome sets in women's and newborn health: a systematic review
Duffy, J. M. N., Rolph, R., Gale, C., Hirsch, M., Khan, K. S., Ziebland, S., & McManus, R. J. (2017). Core outcome sets in women's and newborn health: a systematic review. BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY, 124(10), 1481-1489. doi:10.1111/1471-0528.14694
Identifying research priorities for effective retention strategies in clinical trials
Kearney, A., Daykin, A., Shaw, A. R. G., Lane, A. J., Blazeby, J. M., Clarke, M., . . . Gamble, C. (2017). Identifying research priorities for effective retention strategies in clinical trials. Trials, 18. doi:10.1186/s13063-017-2132-z
Using routinely recorded data in the UK to assess outcomes in a randomised controlled trial: The Trials of Access
Powell, G., Bonnett, L., Tudur-Smith, C., Hughes, D., Marson, A., & Williamson, P. (2017). Using routinely recorded data in the UK to assess outcomes in a randomised controlled trial: The Trials of Access. TRIALS, 18. Retrieved from http://gateway.webofknowledge.com/
Using routinely recorded data in the UK to assess outcomes in a randomised controlled trial: The Trials of Access
Powell, G., Bonnett, L., Tudur-Smith, C., Hughes, D., Marson, A., & Williamson, P. (2017). Using routinely recorded data in the UK to assess outcomes in a randomised controlled trial: The Trials of Access. In TRIALS Vol. 18. Retrieved from http://gateway.webofknowledge.com/
Do systematic reviews still exclude studies with "no relevant outcome data"?
Dwan, K. M., Williamson, P. R., & Kirkham, J. J. (2017). Do systematic reviews still exclude studies with "no relevant outcome data"?. BMJ (Clinical research ed.), 358, j3919. doi:10.1136/bmj.j3919
The impact of outcome reporting bias in randomised controlled trials on a cohort of systematic reviews [Excluded studies response]
Dwan, K. M., Williamson, P. R., & Kirkham, J. J. (2017). The impact of outcome reporting bias in randomised controlled trials on a cohort of systematic reviews [Excluded studies response]. BMJ: British Medical Journal. Retrieved from http://www.bmj.com/content/340/bmj.c365/rr
Standardising the reporting of outcomes in gastric cancer surgery trials: protocol for the development of a core outcome set and accompanying outcome measurement instrument set (the GASTROS study)
Alkhaffaf, B., Glenny, A. -M., Blazeby, J. M., Williamson, P., & Bruce, I. A. (2017). Standardising the reporting of outcomes in gastric cancer surgery trials: protocol for the development of a core outcome set and accompanying outcome measurement instrument set (the GASTROS study). TRIALS, 18. doi:10.1186/s13063-017-2100-7
Core outcome research measures in anal cancer
Fish, R., Sebag-Montefiore, D., Sanders, C., Williamson, P., & Renehan, A. (2017). Core outcome research measures in anal cancer. COLORECTAL DISEASE, 19(8), 782-783. doi:10.1111/codi.13776
Protocol for an online randomised controlled trial to evaluate the clinical and cost-effectiveness of a peer-supported self-management intervention for relatives of people with psychosis or bipolar disorder: Relatives Education And Coping Toolkit (REACT)
Lobban, F., Robinson, H., Appelbe, D., Barraclough, J., Bedson, E., Collinge, L., . . . Jones, S. (2017). Protocol for an online randomised controlled trial to evaluate the clinical and cost-effectiveness of a peer-supported self-management intervention for relatives of people with psychosis or bipolar disorder: Relatives Education And Coping Toolkit (REACT). BMJ OPEN, 7(7). doi:10.1136/bmjopen-2017-016965
Resource implications of preparing individual participant data from a clinical trial to share with external researchers
Smith, C. T., Nevitt, S., Appelbe, D., Appleton, R., Dixon, P., Harrison, J., . . . Tremain, E. (2017). Resource implications of preparing individual participant data from a clinical trial to share with external researchers. TRIALS, 18. doi:10.1186/s13063-017-2067-4
A NEIGHBOURHOODS AND DEMENTIA STUDY: WHAT IS IMPORTANT TO PEOPLE WITH DEMENTIA VERSUS TRIAL OUTCOMES
Reilly, S., Opdebeeck, C., Morbey, H., Ahmed, F., Williamson, P., Leroi, I., & Keady, J. (2017). A NEIGHBOURHOODS AND DEMENTIA STUDY: WHAT IS IMPORTANT TO PEOPLE WITH DEMENTIA VERSUS TRIAL OUTCOMES. Innovation in Aging, 1(suppl_1), 294. doi:10.1093/geroni/igx004.1090
IMPROVED OUTCOMES OF EMERGENCY ADMISSION FOR ULCERATIVE COLITIS (UC) IN ENGLAND OVER THE LAST DECADE: A TEN YEAR ANALYSIS OF ROUTINE NHS DATA
Shawihdi, M., Dodd, S., Grainger, R., Bloom, S., Cummings, F., Driscoll, R., . . . Bodger, K. (2017). IMPROVED OUTCOMES OF EMERGENCY ADMISSION FOR ULCERATIVE COLITIS (UC) IN ENGLAND OVER THE LAST DECADE: A TEN YEAR ANALYSIS OF ROUTINE NHS DATA. In GUT Vol. 66 (pp. A254). doi:10.1136/gutjnl-2017-314472.495
The COMET Handbook: version 1.0
Williamson, P., Altman, D. G., Bagley, H., Barnes, K. L., Blazeby, J. M., Brookes, S. T., . . . Young, B. (2017). The COMET Handbook: version 1.0. Trials, 18(Suppl 3), 50 pages. doi:10.1186/s13063-017-1978-4
A NEIGHBOURHOODS AND DEMENTIA STUDY: WHAT IS IMPORTANT TO PEOPLE WITH DEMENTIA VERSUS TRIAL OUTCOMES
Reilly, S., Opdebeeck, C., Morbey, H., Ahmed, F., Williamson, P., Leroi, I., & Keady, J. (2017). A NEIGHBOURHOODS AND DEMENTIA STUDY: WHAT IS IMPORTANT TO PEOPLE WITH DEMENTIA VERSUS TRIAL OUTCOMES. Innovation in aging, 1(Suppl 1), 294.
Citation analysis did not provide a reliable assessment of core outcome set uptake
Barnes, K. L., Kirkham, J. J., Clarke, M., & Williamson, P. R. (2017). Citation analysis did not provide a reliable assessment of core outcome set uptake. JOURNAL OF CLINICAL EPIDEMIOLOGY, 86, 153-159. doi:10.1016/j.jclinepi.2017.03.003
Improving core outcome set development: qualitative interviews with developers provided pointers to inform guidance
Gargon, E., Williamson, P. R., & Young, B. (2017). Improving core outcome set development: qualitative interviews with developers provided pointers to inform guidance. JOURNAL OF CLINICAL EPIDEMIOLOGY, 86, 140-152. doi:10.1016/j.jclinepi.2017.04.024
OUTCOME MEASUREMENT INSTRUMENTS FOR SAFETY IN RHEUMATOLOGY: A SCOPING REVIEW OF AVAILABLE INSTRUMENTS TO INFORM THE OMERACT SAFETY WORKING GROUP
Klokker, L., Woodworth, T., Furst, D. E., Tugwell, P., Devoe, D., Williamson, P., . . . Christensen, R. (2017). OUTCOME MEASUREMENT INSTRUMENTS FOR SAFETY IN RHEUMATOLOGY: A SCOPING REVIEW OF AVAILABLE INSTRUMENTS TO INFORM THE OMERACT SAFETY WORKING GROUP. In ANNALS OF THE RHEUMATIC DISEASES Vol. 76 (pp. 463). doi:10.1136/annrheumdis-2017-eular.6141
A methodological approach for assessing the uptake of core outcome sets using ClinicalTrials.gov: findings from a review of randomised controlled trials of rheumatoid arthritis.
Kirkham, J. J., Clarke, M., & Williamson, P. R. (n.d.). A methodological approach for assessing the uptake of core outcome sets using ClinicalTrials.gov: findings from a review of randomised controlled trials of rheumatoid arthritis.. BMJ: British Medical Journal, 357. doi:10.1136/bmj.j2262
Informing efficient randomised controlled trials: exploration of challenges in developing progression criteria for internal pilot studies
Avery, K. N. L., Williamson, P. R., Gamble, C., Francischetto, E. O., Metcalfe, C., Davidson, P., . . . Sup, I. P. T. W. (2017). Informing efficient randomised controlled trials: exploration of challenges in developing progression criteria for internal pilot studies. BMJ OPEN, 7. doi:10.1136/bmjopen-2016-013537
What might a global health trials methodology research agenda look like?
Rosala-Hallas, A., & Williamson, P. R. (2017). What might a global health trials methodology research agenda look like?. In TRIALS Vol. 18. Retrieved from https://www.webofscience.com/
Adalimumab plus Methotrexate for Uveitis in Juvenile Idiopathic Arthritis
Ramanan, A. V., Dick, A. D., Jones, A. P., McKay, A., Williamson, P. R., Compeyrot-Lacassagne, S., . . . Grp, S. Y. C. A. M. O. R. E. S. (2017). Adalimumab plus Methotrexate for Uveitis in Juvenile Idiopathic Arthritis. New England Journal of Medicine, 376(17), 1637-1646. doi:10.1056/NEJMoa1614160
Clinical trials and systematic reviews addressing similar interventions for the same condition do not consider similar outcomes to be important: a case study in HIV/AIDS
Saldanha, I. J., Li, T., Yang, C., Owczarzak, J., Williamson, P. R., & Dickersin, K. (2017). Clinical trials and systematic reviews addressing similar interventions for the same condition do not consider similar outcomes to be important: a case study in HIV/AIDS. JOURNAL OF CLINICAL EPIDEMIOLOGY, 84, 85-94. doi:10.1016/j.jclinepi.2017.02.005
Systematic Literature Review of Outcomes after Surgery for Cauda Equina Syndrome
Srikandarajah, N., Noble, A., Clark, S., Wilby, M., Williamson, P., & Marson, T. (2017). Systematic Literature Review of Outcomes after Surgery for Cauda Equina Syndrome. The Spine Journal, 17(3), S26-S27. doi:10.1016/j.spinee.2016.12.082
TREatment of ATopic eczema (TREAT) Registry Taskforce: protocol for an international Delphi exercise to identify a core set of domains and domain items for national atopic eczema registries
Gerbens, L. A. A., Boyce, A. E., Wall, D., Barbarot, S., de Booij, R. J., Deleuran, M., . . . Flohr, C. (2017). TREatment of ATopic eczema (TREAT) Registry Taskforce: protocol for an international Delphi exercise to identify a core set of domains and domain items for national atopic eczema registries. TRIALS, 18. doi:10.1186/s13063-016-1765-7
Informing efficient randomised controlled trials: exploration of challenges in developing progression criteria for internal pilot studies
Avery, K. N. L., Williamson, P. R., Gamble, C., Francischetto, E. O., Metcalfe, C., Davidson, P., . . . Blazeby, J. M. (2017). Informing efficient randomised controlled trials: exploration of challenges in developing progression criteria for internal pilot studies. BMJ OPEN, 7(2). doi:10.1136/bmjopen-2016-013537
The COMET Initiative database: progress and activities update (2015)
Gargon, E., Williamson, P. R., Altman, D. G., Blazeby, J. M., Tunis, S., & Clarke, M. (2017). The COMET Initiative database: progress and activities update (2015). TRIALS, 18. doi:10.1186/s13063-017-1788-8
A study aimed at improving the conduct and efficiency of trials by developing a standardised set of site performance metrics and a systematic approach to reporting
Whitham, D., Turzanski, J., Montgomery, A., Duley, L., Treweek, S., Williamson, P., . . . Lambert, L. (2017). A study aimed at improving the conduct and efficiency of trials by developing a standardised set of site performance metrics and a systematic approach to reporting. In TRIALS Vol. 18. Retrieved from https://www.webofscience.com/
Are the priorities of patients & researchers aligned in the reporting of outcomes following gastric cancer surgery trials?
Alkhaffaf, B., Bruce, I., Glenny, A. -M., Williamson, P., Blazeby, J., & Morris, R. (2017). Are the priorities of patients & researchers aligned in the reporting of outcomes following gastric cancer surgery trials?. In BRITISH JOURNAL OF SURGERY Vol. 104 (pp. 57). Retrieved from https://www.webofscience.com/
Assessing the impact of a funder's recommendation on consideration and uptake of core outcome sets in funding applications
Barnes, K., Kirkham, J. J., Clarke, M., & Williamson, P. R. (2017). Assessing the impact of a funder's recommendation on consideration and uptake of core outcome sets in funding applications. In TRIALS Vol. 18. Retrieved from https://www.webofscience.com/
Collating the evidence base to facilitate patient and public involvement in core outcome set development - A qualitative meta-synthesis
Brading, L., Woolfall, K., Williamson, P., & Young, B. (2017). Collating the evidence base to facilitate patient and public involvement in core outcome set development - A qualitative meta-synthesis. In TRIALS Vol. 18. Retrieved from https://www.webofscience.com/
Completeness of outcome reporting across 79 randomised trials, 31 615 participants, evaluating therapeutic interventions for pre-eclampsia: a systematic review
Duffy, J. M. N., Hirsch, M., Kawsar, A., Gale, C., Pealing, L., Plana, M., . . . McManus, R. J. (2017). Completeness of outcome reporting across 79 randomised trials, 31 615 participants, evaluating therapeutic interventions for pre-eclampsia: a systematic review. In BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY Vol. 124 (pp. 123). Retrieved from https://www.webofscience.com/
Completeness of safety reporting in 79 randomised trials, 31 615 participants, evaluating therapeutic interventions for pre-eclampsia: A systematic review
Duffy, J. M. N., Hirsch, M., Kawsar, A., Pealing, L., Showell, M., Williamson, P., . . . McManus, R. J. (2017). Completeness of safety reporting in 79 randomised trials, 31 615 participants, evaluating therapeutic interventions for pre-eclampsia: A systematic review. In BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY Vol. 124 (pp. 37). Retrieved from https://www.webofscience.com/
Developing a pre-eclampsia core outcome set. Round 1 results: 283 healthcare professionals, 41 researchers and 112 patients from 55 countries participated
Duffy, J. M. N., van't Hooft, J., Gale, C., Brown, M., Grobman, W., Fitzpatrick, R., . . . McManus, R. J. (2017). Developing a pre-eclampsia core outcome set. Round 1 results: 283 healthcare professionals, 41 researchers and 112 patients from 55 countries participated. In BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY Vol. 124 (pp. 151-152). Retrieved from https://www.webofscience.com/
Duration of intravenous antibiotic therapy for children with acute osteomyelitis or septic arthritis: a feasibility study
de Graaf, H., Sukhtankar, P., Arch, B., Ahmad, N., Lees, A., Bennett, A., . . . Faust, S. N. (2017). Duration of intravenous antibiotic therapy for children with acute osteomyelitis or septic arthritis: a feasibility study. HEALTH TECHNOLOGY ASSESSMENT, 21(48), 1-+. Retrieved from https://www.webofscience.com/
Identifying effective retention strategies: a research agenda
Kearney, A., Daykin, A., Heawood, A. J., Lane, A., Blazeby, J., Clarke, M., . . . Gamble, C. (2017). Identifying effective retention strategies: a research agenda. In TRIALS Vol. 18. Retrieved from https://www.webofscience.com/
Implementing and running an online trial - a case study using the react trial
Appelbe, D., Robinson, H., Dodd, S., Walker, A., Williamson, P., & Lobban, F. (2017). Implementing and running an online trial - a case study using the react trial. In TRIALS Vol. 18. Retrieved from https://www.webofscience.com/
Measuring The Metrics Of Outcomes In Trials Of Physical Rehabilitation During Critical Illness And Recovery; a Systematic Review
Connolly, B., Allum, L., Granger, C. L., Mortimore, J., Denehy, L., Williamson, P., . . . Blackwood, B. (2017). Measuring The Metrics Of Outcomes In Trials Of Physical Rehabilitation During Critical Illness And Recovery; a Systematic Review. In AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE Vol. 195. Retrieved from https://www.webofscience.com/
Methods for including patients in core outcome set development
Biggane, A., Brading, L., Young, B., Ravaud, P., & Williamson, P. R. (2017). Methods for including patients in core outcome set development. In TRIALS Vol. 18. Retrieved from https://www.webofscience.com/
Multivariate meta-analysis methods for bias reduction in systematic reviews
Frosi, G. (2017). Multivariate meta-analysis methods for bias reduction in systematic reviews.
Online resource for recruitment research in clinical trials research (ORRCA)
Kearney, A., Harman, N. L., Bacon, N., Daykin, A., Heawood, A. J., Lane, A., . . . Bower, P. (2017). Online resource for recruitment research in clinical trials research (ORRCA). In TRIALS Vol. 18. Retrieved from https://www.webofscience.com/
Outcome selection in clinical trials - Looking back at the problems and moving forward with solutions
Williamson, P., Kirkham, J. K., Gamble, C., & Dwan, K. (2017). Outcome selection in clinical trials - Looking back at the problems and moving forward with solutions. In TRIALS Vol. 18. Retrieved from https://www.webofscience.com/
Primary outcome and outcome measure reporting in pre-eclampsia trials. A systematic review of 79 randomised trials reporting data from 31 615 participants
Duffy, J. M. N., Hirsch, M., Gale, C., Pealing, L., Kawsar, A., Showell, M., . . . McManus, R. J. (2017). Primary outcome and outcome measure reporting in pre-eclampsia trials. A systematic review of 79 randomised trials reporting data from 31 615 participants. In BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY Vol. 124 (pp. 122-123). Retrieved from https://www.webofscience.com/
Prioritising recruitment in randomised trials: the priority study-an Ireland and UK priority setting partnership
Healy, P., Galvin, S., Treweek, S., Whiting, C., Maeso, B., Williamson, P., . . . Clarke-Moloney, M. (2017). Prioritising recruitment in randomised trials: the priority study-an Ireland and UK priority setting partnership. In TRIALS Vol. 18. Retrieved from https://www.webofscience.com/
Priority setting for core outcome set development
Gorst, S., Clark, M., & Williamson, P. R. (2017). Priority setting for core outcome set development. In TRIALS Vol. 18. Retrieved from https://www.webofscience.com/
RESULTS OF THE EUROPEAN LEAGUE AGAINST RHEUMATISM TASK FORCE FOR STANDARDIZING A MINIMUM CORE DATASET FOR OBSERVATIONAL RESEARCH IN RHEUMATOID ARTHRITIS
Nikiphorou, E., Radner, H., Chatzidionysiou, K., Gossec, L., Hyrich, K., Filip, C., . . . Dixon, W. (2017). RESULTS OF THE EUROPEAN LEAGUE AGAINST RHEUMATISM TASK FORCE FOR STANDARDIZING A MINIMUM CORE DATASET FOR OBSERVATIONAL RESEARCH IN RHEUMATOID ARTHRITIS. In RHEUMATOLOGY Vol. 56 (pp. 115-116). Retrieved from https://www.webofscience.com/
Reducing attrition: the communication of retention and withdrawal within patient information sheets
Kearney, A., Rosala-Hallas, A., Bacon, N., Daykin, A., Heawood, A. J., Lane, A., . . . Gamble, C. (2017). Reducing attrition: the communication of retention and withdrawal within patient information sheets. In TRIALS Vol. 18. Retrieved from https://www.webofscience.com/
Reported reasons for missing data
Kearney, A., Rosala-Hallas, A., Bacon, N., Daykin, A., Heawood, A. J., Lane, A., . . . Gamble, C. (2017). Reported reasons for missing data. In TRIALS Vol. 18. Retrieved from https://www.webofscience.com/
Reporting of outcomes in gastric cancer surgery trials: a systematic review
Alkhaffaf, B., Bruce, I., Williamson, P., Blazeby, J., & Glenny, A. M. (2017). Reporting of outcomes in gastric cancer surgery trials: a systematic review. In EUROPEAN JOURNAL OF CANCER Vol. 72 (pp. S134). Retrieved from https://www.webofscience.com/
SAFETY OF INDIVIDUALISED VARIABLE INTERVAL SCREENING FOR REFERABLE DIABETIC RETINOPATHY: BASELINE DATA FROM THE ISDR RANDOMISED CONTROLLED STUDY
Harding, S. P., Cheyne, C. P., Broadbent, D. M., Appelbe, D., Wang, A., Rahni, M., . . . Finana, M. G. (2017). SAFETY OF INDIVIDUALISED VARIABLE INTERVAL SCREENING FOR REFERABLE DIABETIC RETINOPATHY: BASELINE DATA FROM THE ISDR RANDOMISED CONTROLLED STUDY. In EUROPEAN JOURNAL OF OPHTHALMOLOGY Vol. 27 (pp. E126). Retrieved from https://www.webofscience.com/
Standardised taxonomy for the classification of trial outcomes within core outcome sets and cochrane reviews
Dodd, S., Williamson, P. R., Blazeby, J., & Clarke, M. (2017). Standardised taxonomy for the classification of trial outcomes within core outcome sets and cochrane reviews. In TRIALS Vol. 18. Retrieved from https://www.webofscience.com/
The GASTROS study: standardising outcome reporting in gastric cancer surgery research
Alkhaffaf, B., Bruce, I., Glenny, A. M., Williamson, P., & Blazeby, J. (2017). The GASTROS study: standardising outcome reporting in gastric cancer surgery research. In EUROPEAN JOURNAL OF CANCER Vol. 72 (pp. S134). Retrieved from https://www.webofscience.com/
2016
A survey of facilitators and barriers to recruitment to the MAGNETIC trial
Kaur, G., Smyth, R. L., Powell, C. V. E., & Williamson, P. (2016). A survey of facilitators and barriers to recruitment to the MAGNETIC trial. TRIALS, 17. doi:10.1186/s13063-016-1724-3
Choosing Important Health Outcomes for Comparative Effectiveness Research: An Updated Review and Identification of Gaps
Gorst, S. L., Gargon, E., Clarke, M., Smith, V., & Williamson, P. R. (2016). Choosing Important Health Outcomes for Comparative Effectiveness Research: An Updated Review and Identification of Gaps. PLOS ONE, 11(12). doi:10.1371/journal.pone.0168403
The GASTROS Study: Standardising outcome reporting in gastric cancer surgery research
Alkhaffaf, B., Glenny, A. -M., Blazeby, J., Williamson, P., & Bruce, I. (2016). The GASTROS Study: Standardising outcome reporting in gastric cancer surgery research. International Journal of Surgery, 36, S138. doi:10.1016/j.ijsu.2016.11.037
A core outcome set for neonatal abstinence syndrome: study protocol for a systematic review, parent interviews and a Delphi survey
Kelly, L. E., Jansson, L. M., Moulsdale, W., Pereira, J., Simpson, S., Guttman, A., . . . Offringa, M. (2016). A core outcome set for neonatal abstinence syndrome: study protocol for a systematic review, parent interviews and a Delphi survey. TRIALS, 17. doi:10.1186/s13063-016-1666-9
Questioning assent: how are children's views included as families make decisions about clinical trials?
Madden, L., Shilling, V., Woolfall, K., Sowden, E., Smyth, R. L., Williamson, P. R., & Young, B. (2016). Questioning assent: how are children's views included as families make decisions about clinical trials?. CHILD CARE HEALTH AND DEVELOPMENT, 42(6), 900-908. doi:10.1111/cch.12347
Reporting of outcomes in gastric cancer surgery trials: A systematic review
Alkhaffaf, B., Bruce, I., Williamson, P., Blazeby, J., & Glenny, A. -M. (2016). Reporting of outcomes in gastric cancer surgery trials: A systematic review. European Journal of Surgical Oncology (EJSO), 42(11), S220. doi:10.1016/j.ejso.2016.07.029
Core Outcome Set–STAndards for Reporting: The COS-STAR Statement
Kirkham, J. J., Gorst, S., Altman, D. G., Blazeby, J. M., Clarke, M., Devane, D., . . . Williamson, P. R. (2016). Core Outcome Set–STAndards for Reporting: The COS-STAR Statement. PLoS Medicine, 13(10). doi:10.1371/journal.pmed.1002148
The iBRA-2 (immediate breast reconstruction and adjuvant therapy audit) study: protocol for a prospective national multicentre cohort study to evaluate the impact of immediate breast reconstruction on the delivery of adjuvant therapy
Dave, R., O'Connell, R., Rattay, T., Tolkien, Z., Barnes, N., Skillman, J., . . . Holcombe, C. (2016). The iBRA-2 (immediate breast reconstruction and adjuvant therapy audit) study: protocol for a prospective national multicentre cohort study to evaluate the impact of immediate breast reconstruction on the delivery of adjuvant therapy. BMJ OPEN, 6(10). doi:10.1136/bmjopen-2016-012678
A protocol for developing, disseminating, and implementing a core outcome set for pre-eclampsia
Duffy, J. M. N., Hooft, J. V., Gale, C., Brown, M., Grobman, W., Fitzpatrick, R., . . . McManus, R. J. (2016). A protocol for developing, disseminating, and implementing a core outcome set for pre-eclampsia. PREGNANCY HYPERTENSION-AN INTERNATIONAL JOURNAL OF WOMENS CARDIOVASCULAR HEALTH, 6(4), 274-278. doi:10.1016/j.preghy.2016.04.008
A Randomized Controlled Trial of Extended Brief Intervention for Alcohol-Dependent Patients in an Acute Hospital Setting
Owens, L., Kolamunnage-Dona, R., Owens, A., Perkins, E., Butcher, G., Wilson, K., . . . Pirmohamed, M. (2016). A Randomized Controlled Trial of Extended Brief Intervention for Alcohol-Dependent Patients in an Acute Hospital Setting. Alcohol and Alcoholism, 51(05), 584-592. doi:10.1093/alcalc/agw023
Assessing the feasibility of injectable growth-promoting therapy in Crohn's disease.
Altowati, M. A., Jones, A. P., Hickey, H., Williamson, P. R., Barakat, F. M., Plaatjies, N. C., . . . Sanderson, I. R. (2016). Assessing the feasibility of injectable growth-promoting therapy in Crohn's disease.. Pilot and feasibility studies, 2, 71. doi:10.1186/s40814-016-0112-9
The iBRA (implant breast reconstruction evaluation) study: protocol for a prospective multi-centre cohort study to inform the feasibility, design and conduct of a pragmatic randomised clinical trial comparing new techniques of implant-based breast reconstruction.
Potter, S., Conroy, E. J., Williamson, P. R., Thrush, S., Whisker, L. J., Skillman, J. M., . . . Breast Reconstruction Research Collaborative. (2016). The iBRA (implant breast reconstruction evaluation) study: protocol for a prospective multi-centre cohort study to inform the feasibility, design and conduct of a pragmatic randomised clinical trial comparing new techniques of implant-based breast reconstruction.. Pilot and feasibility studies, 2, 41. doi:10.1186/s40814-016-0085-8
How to select outcome measurement instruments for outcomes included in a "Core Outcome Set" - a practical guideline
Prinsen, C. A. C., Vohra, S., Rose, M. R., Boers, M., Tugwell, P., Clarke, M., . . . Terwee, C. B. (2016). How to select outcome measurement instruments for outcomes included in a "Core Outcome Set" - a practical guideline. TRIALS, 17. doi:10.1186/s13063-016-1555-2
Individual patient data meta-analyses compared with meta-analyses based on aggregate data. (Review)
Tudur Smith, C., Marcucci, M., Nolan, S. J., Iorio, A., Sudell, M., Riley, R., . . . Clarke, M. (2016). Individual patient data meta-analyses compared with meta-analyses based on aggregate data. (Review). The Cochrane Database of Methodology Reviews.. doi:10.1002/14651858.MR000007.pub3
Are we meeting the standards set for endoscopy? Results of a large-scale prospective survey of endoscopic retrograde cholangio-pancreatograph practice (vol 56, pg 821, 2007)
Williams, E. J., Taylor, S., Fairclough, P., & Williamson, P. R. (2016). Are we meeting the standards set for endoscopy? Results of a large-scale prospective survey of endoscopic retrograde cholangio-pancreatograph practice (vol 56, pg 821, 2007). GUT, 65(9), 1571. doi:10.1136/gut.2006.097543corr1
Development of a core outcome set for clinical trials in rosacea: study protocol for a systematic review of the literature and identification of a core outcome set using a Delphi survey
Iyengar, S., Williamson, P. R., Schmitt, J., Johannsen, L., Maher, I. A., Sobanko, J. F., . . . Alam, M. (2016). Development of a core outcome set for clinical trials in rosacea: study protocol for a systematic review of the literature and identification of a core outcome set using a Delphi survey. TRIALS, 17. doi:10.1186/s13063-016-1554-3
Trial outcomes and information for clinical decision-making: a comparative study of opinions of health professionals
McNair, A. G. K., Brookes, S. T., Whistance, R. N., Forsythe, R. O., Macefield, R., Rees, J., . . . Blazeby, J. M. (2016). Trial outcomes and information for clinical decision-making: a comparative study of opinions of health professionals. TRIALS, 17. doi:10.1186/s13063-016-1492-0
Trial outcomes and information for clinical decision-making: a comparative study of opinions of health professionals.
McNair, A. G. K., Brookes, S. T., Whistance, R. N., Forsythe, R. O., Macefield, R., Rees, J., . . . CONSENSUS-CRC (Core Outcomes and iNformation SEts iN SUrgical Studies – ColoRectal Cancer) working group. (2016). Trial outcomes and information for clinical decision-making: a comparative study of opinions of health professionals.. Trials, 17(1), 344. doi:10.1186/s13063-016-1492-0
23 Completeness of outcome and outcome measure reporting across seventy-nine randomised trials, 31,615 participants, evaluating therapeutic interventions for pre-eclampsia: A systematic review
Duffy, J. M. N., Hirsch, M., Kawsar, A., Gale, C., Pealing, L., Plana, M., . . . Mcmanus, R. (2016). 23 Completeness of outcome and outcome measure reporting across seventy-nine randomised trials, 31,615 participants, evaluating therapeutic interventions for pre-eclampsia: A systematic review. Pregnancy Hypertension: An International Journal of Women's Cardiovascular Health, 6(3), 148. doi:10.1016/j.preghy.2016.08.024
Joint modelling of longitudinal outcomes and clinical endpoints: JoineR & JoineR-M
Hickey, G. L., Philipson, P., Jorgensen, A., Henderson, R., Diggle, P., Williamson, P., & Kolamunnage-Dona, R. (2016). Joint modelling of longitudinal outcomes and clinical endpoints: JoineR & JoineR-M. Poster session presented at the meeting of MRC Festival of Medical Research. Victoria Gallery and Museum, University of Liverpool.
ADALIMUMAB IN COMBINATION WITH METHOTREXATE FOR THE TREATMENT OF JUVENILE IDIOPATHIC ARTHRITIS ASSOCIATED UVEITIS: THE SYCAMORE TRIAL
Ramanan, A. V., Dick, A. D., Jones, A. P., McKay, A., Williamson, P. R., Compeyrot-Lacassagne, S., . . . Beresford, M. W. (2016). ADALIMUMAB IN COMBINATION WITH METHOTREXATE FOR THE TREATMENT OF JUVENILE IDIOPATHIC ARTHRITIS ASSOCIATED UVEITIS: THE SYCAMORE TRIAL. In ANNALS OF THE RHEUMATIC DISEASES Vol. 75 (pp. 264-265). doi:10.1136/annrheumdis-2016-eular.6053
DEVELOPMENT OF INFORMATICS TOOLS FOR THE UK IBD REGISTRY USING ROUTINE DATA: PROFILING OF NATIONAL-LEVEL HOSPITAL ACTIVITY FOR IBD PATIENTS IN ENGLAND
Shawihdi, M., Osborne, A., Devonport, E., Driscoll, R., Cummings, F., Bloom, S., . . . Bodger, K. (2016). DEVELOPMENT OF INFORMATICS TOOLS FOR THE UK IBD REGISTRY USING ROUTINE DATA: PROFILING OF NATIONAL-LEVEL HOSPITAL ACTIVITY FOR IBD PATIENTS IN ENGLAND. In GUT Vol. 65 (pp. A208-A209). doi:10.1136/gutjnl-2016-312388.388
How Much Participant Outcome Data Is Missing from Sight: Findings from a Cohort of Trials Submitted to a German Research Ethics Committee
Kirkham, J. J., Dwan, K. M., Bluemle, A., von Elm, E., & Williamson, P. R. (2016). How Much Participant Outcome Data Is Missing from Sight: Findings from a Cohort of Trials Submitted to a German Research Ethics Committee. PLOS ONE, 11(6). doi:10.1371/journal.pone.0157883
THE EULAR TASK FORCE FOR STANDARDISING MINIMUM DATA COLLECTION IN RHEUMATOID ARTHRITIS OBSERVATIONAL RESEARCH: RESULTS OF A HIERARCHICAL LITERATURE REVIEW
Chatzidionysiou, K., Nikiphorou, E., Gossec, L., Hyrich, K., Filip, C., van Eijk-Hustings, Y., . . . Radner, H. (2016). THE EULAR TASK FORCE FOR STANDARDISING MINIMUM DATA COLLECTION IN RHEUMATOID ARTHRITIS OBSERVATIONAL RESEARCH: RESULTS OF A HIERARCHICAL LITERATURE REVIEW. In ANNALS OF THE RHEUMATIC DISEASES Vol. 75 (pp. 166). doi:10.1136/annrheumdis-2016-eular.4631
TRENDS IN MORTALITY FOR IBD PATIENTS ADMITTED AS AN EMERGENCY TO ENGLISH HOSPITALS: A 10-YEAR ANALYSIS OF ROUTINE ADMINISTRATIVE DATA
Shawihdi, M., Driscoll, R., Pearson, M., Cummings, F., Bloom, S., Williamson, P., & Bodger, K. (2016). TRENDS IN MORTALITY FOR IBD PATIENTS ADMITTED AS AN EMERGENCY TO ENGLISH HOSPITALS: A 10-YEAR ANALYSIS OF ROUTINE ADMINISTRATIVE DATA. In GUT Vol. 65 (pp. A83-A84). doi:10.1136/gutjnl-2016-312388.149
A randomised controlled trial of extended brief intervention for alcohol dependent patients in an acute hospital setting (ADPAC)
Owens, L., Butcher, G., Gilmore, I., Kolamunnage-Dona, R., Oyee, J., Perkins, L., . . . Pirmohamed, M. (2011). A randomised controlled trial of extended brief intervention for alcohol dependent patients in an acute hospital setting (ADPAC). BMC Public Health, 11, 528.
The use of qualitative methods to inform Delphi surveys in core outcome set development
Keeley, T., Williamson, P., Callery, P., Jones, L. L., Mathers, J., Jones, J., . . . Calvert, M. (2016). The use of qualitative methods to inform Delphi surveys in core outcome set development. TRIALS, 17. doi:10.1186/s13063-016-1356-7
The UK Lung Cancer Screening Trial: a pilot randomised controlled trial of low-dose computed tomography screening for the early detection of lung cancer.
Field, J. K., Duffy, S. W., Baldwin, D. R., Brain, K. E., Devaraj, A., Eisen, T., . . . Hansell, D. M. (2016). The UK Lung Cancer Screening Trial: a pilot randomised controlled trial of low-dose computed tomography screening for the early detection of lung cancer.. Health Technology Assessment, 20(40), 1-146. doi:10.3310/hta20400
Modelling variable dropout in randomised controlled trials with longitudinal outcomes: Application to the MAGNETIC study
Kolamunnage-Dona, R., Powell, C., & Williamson, P. R. (2016). Modelling variable dropout in randomised controlled trials with longitudinal outcomes: Application to the MAGNETIC study. Trials, 17. doi:10.1186/s13063-016-1342-0
A patient and public involvement (PPI) toolkit for meaningful and flexible involvement in clinical trials - a work in progress.
Bagley, H. J., Short, H., Harman, N. L., Hickey, H. R., Gamble, C. L., Woolfall, K., . . . Williamson, P. R. (2016). A patient and public involvement (PPI) toolkit for meaningful and flexible involvement in clinical trials - a work in progress.. Research involvement and engagement, 2, 15. doi:10.1186/s40900-016-0029-8
Feasibility study to examine discrepancy rates in prespecified and reported outcomes in articles submitted to The BMJ
Weston, J., Dwan, K., Altman, D., Clarke, M., Gamble, C., Schroter, S., . . . Kirkham, J. J. (2016). Feasibility study to examine discrepancy rates in prespecified and reported outcomes in articles submitted to The BMJ. BMJ Open, 6(4). doi:10.1136/bmjopen-2015-010075
Improving the relevance and consistency of outcomes in comparative effectiveness research
Tunis, S. R., Clarke, M., Gorst, S. L., Gargon, E., Blazeby, J. M., Altman, D. G., & Williamson, P. R. (2016). Improving the relevance and consistency of outcomes in comparative effectiveness research. JOURNAL OF COMPARATIVE EFFECTIVENESS RESEARCH, 5(2), 193-205. doi:10.2217/cer-2015-0007
Re: Methodological issues on the development of a core outcome set for spine trauma. Re: Cumhur Oner et al (Toward the Development of a Universal Outcome Instrument for Spine Trauma-A Systematic Review and Content Comparison of Outcome Measures used in Spine Trauma Research Using the ICF as Reference)
Kolias, A. G., Williamson, P. R., & Blazeby, J. M. (2016). Re: Methodological issues on the development of a core outcome set for spine trauma. Re: Cumhur Oner et al (Toward the Development of a Universal Outcome Instrument for Spine Trauma-A Systematic Review and Content Comparison of Outcome Measures used in Spine Trauma Research Using the ICF as Reference). SPINE, 41(5), E301-E302. doi:10.1097/BRS.0000000000001410
The need for consensus, consistency, and core outcome sets in perioperative research
Blazeby, J. M., Williamson, P. R., & Altman, D. (2016). The need for consensus, consistency, and core outcome sets in perioperative research. CANADIAN JOURNAL OF ANESTHESIA-JOURNAL CANADIEN D ANESTHESIE, 63(2), 133-137. doi:10.1007/s12630-015-0529-2
UK publicly funded Clinical Trials Units supported a controlled access approach to share individual participant data but highlighted concerns
Hopkins, C., Sydes, M., Murray, G., Woolfall, K., Clarke, M., Williamson, P., & Smith, C. T. (2016). UK publicly funded Clinical Trials Units supported a controlled access approach to share individual participant data but highlighted concerns. JOURNAL OF CLINICAL EPIDEMIOLOGY, 70, 17-25. doi:10.1016/j.jclinepi.2015.07.002
Core outcome sets and systematic reviews
Clarke, M., & Williamson, P. R. (2016). Core outcome sets and systematic reviews. SYSTEMATIC REVIEWS, 5. doi:10.1186/s13643-016-0188-6
UK Lung Cancer RCT Pilot Screening Trial: baseline findings from the screening arm provide evidence for the potential implementation of lung cancer screening
Field, J. K., Duffy, S. W., Baldwin, D. R., Whynes, D. K., Devaraj, A., Brain, K. E., . . . Hansell, D. M. (2016). UK Lung Cancer RCT Pilot Screening Trial: baseline findings from the screening arm provide evidence for the potential implementation of lung cancer screening. Thorax, 71(2), 161-170. doi:10.1136/thoraxjnl-2015-207140
A multi-factorial analysis of response to warfarin in a UK prospective cohort
Bourgeois, S., Jorgensen, A., Zhang, E. J., Hanson, A., Gillman, M. S., Bumpstead, S., . . . Pirmohamed, M. (2016). A multi-factorial analysis of response to warfarin in a UK prospective cohort. Genome Medicine: medicine in the post-genomic era, 8. doi:10.1186/s13073-015-0255-y
A Core Outcome Set for Evaluation of Interventions to Prevent Preterm Birth
van 't Hooft, J., Duffy, J. M. N., Daly, M., Williamson, P. R., Meher, S., Thom, E., . . . GONet, G. O. N. (2016). A Core Outcome Set for Evaluation of Interventions to Prevent Preterm Birth. OBSTETRICS AND GYNECOLOGY, 127(01), 49-58. doi:10.1097/AOG.0000000000001195
Can core outcome sets designed for research inform the standardisation of outcome measurement in primary care?
Keeley, T., Sayers, R., Pinfold, V., Mathers, J., Williamson, P., & Calvert, M. J. (2016). Can core outcome sets designed for research inform the standardisation of outcome measurement in primary care?. In QUALITY OF LIFE RESEARCH Vol. 25 (pp. 9-10). Retrieved from https://www.webofscience.com/
Choosing Important Health Outcomes for Comparative Effectiveness Research: An Updated Review and User Survey
Gorst, S. L., Gargon, E., Clarke, M., Blazeby, J. M., Altman, D. G., & Williamson, P. R. (2016). Choosing Important Health Outcomes for Comparative Effectiveness Research: An Updated Review and User Survey. PLOS ONE, 11(1). doi:10.1371/journal.pone.0146444
Completeness of outcome and outcome measure reporting across seventy-nine randomised trials, 31,615 participants, evaluating therapeutic interventions for pre-eclampsia: a systematic review
Duffy, J., Hirsch, M., Kawsar, A., Pealing, L., Showell, M., Plana, M., . . . McManus, R. (2016). Completeness of outcome and outcome measure reporting across seventy-nine randomised trials, 31,615 participants, evaluating therapeutic interventions for pre-eclampsia: a systematic review. In JOURNAL OF HUMAN HYPERTENSION Vol. 30 (pp. 642). Retrieved from https://www.webofscience.com/
Core outcome sets (COS) and the core outcome measures in effectiveness trials (COMET) initiative: patient participation in COS development
Williamson, P., Gargon, E., Gorst, S., Altman, D., Blazeby, J., Clarke, M., & Tunis, S. (2016). Core outcome sets (COS) and the core outcome measures in effectiveness trials (COMET) initiative: patient participation in COS development. In QUALITY OF LIFE RESEARCH Vol. 25 (pp. 68). Retrieved from https://www.webofscience.com/
Reporting of Outcomes in Gastric Cancer Surgery Trials: A Systematic Review
Alkhaffaf, B., Bruce, I., Williamson, P., Blazeby, J., & Glenny, A. -M. (2016). Reporting of Outcomes in Gastric Cancer Surgery Trials: A Systematic Review. In BRITISH JOURNAL OF SURGERY Vol. 103 (pp. 57). Retrieved from https://www.webofscience.com/
The GASTROS Study: Standardising Outcome Reporting in Gastric Cancer Surgery Research
Alkhaffaf, B., Bruce, I. A., Glenny, A. M., Williamson, P. R., & Blazeby, J. M. (2016). The GASTROS Study: Standardising Outcome Reporting in Gastric Cancer Surgery Research. BRITISH JOURNAL OF SURGERY, 103, 143. Retrieved from https://www.webofscience.com/
The GASTROS Study: Standardising Outcome Reporting in Gastric Cancer Surgery Research
Alkhaffaf, B., Bruce, I., Glenny, A. -M., Williamson, P., & Blazeby, J. (2016). The GASTROS Study: Standardising Outcome Reporting in Gastric Cancer Surgery Research. In BRITISH JOURNAL OF SURGERY Vol. 103 (pp. 49). Retrieved from https://www.webofscience.com/
Towards Harmonized Data Collection in Rheumatoid Arthritis (RA): The EULAR Task Force for Standardizing a Minimum Data Collection for RA Observational Research
Radner, H., Nikiphorou, E., Chatzidionysiou, K., Gossec, L., Hyrich, K. L., Zabalan, C., . . . Askling, J. (2016). Towards Harmonized Data Collection in Rheumatoid Arthritis (RA): The EULAR Task Force for Standardizing a Minimum Data Collection for RA Observational Research. In ARTHRITIS & RHEUMATOLOGY Vol. 68. Retrieved from https://www.webofscience.com/
2015
How should individual participant data (IPD) from publicly funded clinical trials be shared?
Smith, C. T., Hopkins, C., Sydes, M. R., Woolfall, K., Clarke, M., Murray, G., & Williamson, P. (2015). How should individual participant data (IPD) from publicly funded clinical trials be shared?. BMC MEDICINE, 13. doi:10.1186/s12916-015-0532-z
WITHDRAWN: Common antiepileptic drugs in pregnancy in women with epilepsy.
Adab, N., Tudur Smith, C., Vinten, J., Williamson, P. R., Winterbottom, J. B., McKay, A. J., & Bromley, R. (2015). WITHDRAWN: Common antiepileptic drugs in pregnancy in women with epilepsy.. The Cochrane database of systematic reviews, (12), CD004848. doi:10.1002/14651858.cd004848.pub2
"To have, to hold, from this day forward": understanding current practice regarding the retention of trial participants
Daykin, A., Lane, A., Gamble, C., Kearney, A., Blazeby, J., Clarke, M., . . . Heawood, A. (2015). "To have, to hold, from this day forward": understanding current practice regarding the retention of trial participants. In TRIALS Vol. 16. doi:10.1186/1745-6215-16-S2-P104
A mixed methods study of researchers' experiences of developing core outcome sets
Gargon, E., Young, B., & Williamson, P. (2015). A mixed methods study of researchers' experiences of developing core outcome sets. In TRIALS Vol. 16. doi:10.1186/1745-6215-16-S2-P60
A review of the description of patient withdrawal in trial protocols and patient information sheets (PIS)
Kearney, A., Daykin, A., Heawood, A., Lane, A., Blazeby, J., Clarke, M., . . . Gamble, C. (2015). A review of the description of patient withdrawal in trial protocols and patient information sheets (PIS). In TRIALS Vol. 16. doi:10.1186/1745-6215-16-S2-P46
Are patients and health care professionals influenced by each other's' opinions about the outcomes to measure in localised prostate cancer effectiveness trials?
MacLennan, S., Lam, T., & Williamson, P. (2015). Are patients and health care professionals influenced by each other's' opinions about the outcomes to measure in localised prostate cancer effectiveness trials?. In TRIALS Vol. 16. doi:10.1186/1745-6215-16-S2-P64
COMET IV meeting summary
Gargon, E., Altman, D. G., Blazeby, J. M., Clarke, M., & Williamson, P. R. (2015). COMET IV meeting summary. TRIALS, 16. Retrieved from https://www.webofscience.com/
Choosing important health outcomes for comparative effectiveness research: an updated review and user survey
Gorst, S. L., Gargon, E., & Williamson, P. R. (2015). Choosing important health outcomes for comparative effectiveness research: an updated review and user survey. In TRIALS Vol. 16. doi:10.1186/1745-6215-16-S3-P8
Citation analysis: a new approach to assess the uptake of core outcome sets
Barnes, K., Clarke, M., Kirkham, J., & Williamson, P. (2015). Citation analysis: a new approach to assess the uptake of core outcome sets. In TRIALS Vol. 16. doi:10.1186/1745-6215-16-S2-P50
Developing a toolkit for patient and public involvement in a clinical trials unit
Bagley, H., Harman, N., Woolfall, K., Young, B., Short, H., Hickey, H., & Williamson, P. (2015). Developing a toolkit for patient and public involvement in a clinical trials unit. TRIALS, 16. doi:10.1186/1745-6215-16-S2-O92
Development and evaluation of an electronic diary for recording patient reported outcomes in the overt study
Appelbe, D., Adeogun, O., Webb, N., Majeed, R., Lewis, M., & Williamson, P. (2015). Development and evaluation of an electronic diary for recording patient reported outcomes in the overt study. In TRIALS Vol. 16. doi:10.1186/1745-6215-16-S2-O64
Development of an online resource for recruitment research in clinical trials (ORRCA)
Harman, N., Treweek, S., Clarke, M., Williamson, P., Bower, P., & Gamble, C. (2015). Development of an online resource for recruitment research in clinical trials (ORRCA). TRIALS, 16. doi:10.1186/1745-6215-16-S2-P98
Development of guidance for statistical analysis plans (SAPs) for clinical trials
Krishan, A., Stocken, D., Lewis, S., Juszczak, E., Dore, C., Williamson, P., . . . Gamble, C. (2015). Development of guidance for statistical analysis plans (SAPs) for clinical trials. TRIALS, 16. doi:10.1186/1745-6215-16-S2-O41
Evaluation of interventions for informed consent for randomised controlled trials (ELICIT): developing a core outcome set
Gillies, K., Fraser, C., Entwistle, V., Treweek, S., Williamson, P., & Campbell, M. (2015). Evaluation of interventions for informed consent for randomised controlled trials (ELICIT): developing a core outcome set. In TRIALS Vol. 16. doi:10.1186/1745-6215-16-S2-P53
Optimising the design of internal pilot work to inform efficient randomised controlled trials: issues to consider when developing progression criteria
Avery, K., Williamson, P., Gamble, C., Francischetto, E. O., Metcalfe, C., Davidson, P., & Blazeby, J. (2015). Optimising the design of internal pilot work to inform efficient randomised controlled trials: issues to consider when developing progression criteria. In TRIALS Vol. 16. doi:10.1186/1745-6215-16-S2-P10
Pragmatic approaches to mitigating missing data and research priorities to assess the effectiveness of interventions
Kearney, A., Daykin, A., Heawood, A., Lane, A., Blazeby, J., Clarke, M., . . . Gamble, C. (2015). Pragmatic approaches to mitigating missing data and research priorities to assess the effectiveness of interventions. In TRIALS Vol. 16. doi:10.1186/1745-6215-16-S2-P238
Realising the potential of patient and public involvement to make a difference: what can trial teams do?
Young, B., Dudley, L., Williamson, P., & Gamble, C. (2015). Realising the potential of patient and public involvement to make a difference: what can trial teams do?. In TRIALS Vol. 16. doi:10.1186/1745-6215-16-S2-O93
Recruitment progression rules for internal pilot studies monitoring recruitment
Hampson, L., Williamson, P., Wilby, M., & Jaki, T. (2015). Recruitment progression rules for internal pilot studies monitoring recruitment. In TRIALS Vol. 16. doi:10.1186/1745-6215-16-S2-O89
Selective reporting in clinical trials - an examination of discrepancy rates in pre-specified and reported outcomes in articles submitted to the BMJ
Weston, J., Dwan, K., Altman, D., Clarke, M., Gamble, C., Groves, T., . . . Kirkham, J. (2015). Selective reporting in clinical trials - an examination of discrepancy rates in pre-specified and reported outcomes in articles submitted to the BMJ. In TRIALS Vol. 16. doi:10.1186/1745-6215-16-S2-O72
The Patient and Public Involvement Activities of the COMET Initiative
Bagley, H., Young, B., & Williamson, P. R. (2015). The Patient and Public Involvement Activities of the COMET Initiative. In TRIALS Vol. 16. doi:10.1186/1745-6215-16-S3-P7
The core outcome measures in effectiveness trials (COMET) initiative: five years on
Williamson, P., Altman, D., Blazeby, J., Clarke, M., Gargon, E., Gorst, S., & Tunis, S. (2015). The core outcome measures in effectiveness trials (COMET) initiative: five years on. In TRIALS Vol. 16. doi:10.1186/1745-6215-16-S2-P69
Three nested RCTs of dual or single stakeholder feedback within Delphi surveys during core outcome and information set development
Brookes, S., Macefield, R., Williamson, P., McNair, A., Potter, S., Blencowe, N., . . . Blazeby, J. (2015). Three nested RCTs of dual or single stakeholder feedback within Delphi surveys during core outcome and information set development. In TRIALS Vol. 16. doi:10.1186/1745-6215-16-S2-P51
Using qualitative research to understand what outcomes matter to patients: direct and indirect approaches to outcome elicitation
Mathers, J., Keeley, T., Jones, L., Calvert, M., Williamson, P., Jones, J., . . . Young, B. (2015). Using qualitative research to understand what outcomes matter to patients: direct and indirect approaches to outcome elicitation. In TRIALS Vol. 16. doi:10.1186/1745-6215-16-S2-O39
A pilot randomised controlled trial to assess the utility of an e-learning package that trains users in adverse drug reaction causality.
Conroy, E., Kirkham, J., Bellis, J., Peak, M., Smyth, R., Williamson, P., & Pirmohamed, M. (2015). A pilot randomised controlled trial to assess the utility of an e-learning package that trains users in adverse drug reaction causality.. The International Journal of Pharmacy Practice, 23(6), 447-455. doi:10.1111/ijpp.12197
Reported reasons for missing data and the interplay with trial setting
Kearney, A., Bacon, N., Rosala-Hallas, A., Daykin, A., Heawood, A., Lane, A., . . . Gamble, C. (2015). Reported reasons for missing data and the interplay with trial setting. Poster session presented at the meeting of 3rd International Clinical Trials Methodology Conference. Glasgow UK.
The COMET initiative database: progress and activities update (2014)
Gargon, E., Williamson, P. R., Altman, D. G., Blazeby, J. M., & Clarke, M. (2015). The COMET initiative database: progress and activities update (2014). Trials, 16. doi:10.1186/s13063-015-1038-x
A MIXED METHODS STUDY OF RESEARCHERS' EXPERIENCES OF DEVELOPING CORE OUTCOME SETS
Gargon, E., Young, B., & Williamson, P. R. (2015). A MIXED METHODS STUDY OF RESEARCHERS' EXPERIENCES OF DEVELOPING CORE OUTCOME SETS. VALUE IN HEALTH, 18(7), A724. doi:10.1016/j.jval.2015.09.2752
Evaluation of interventions for informed consent for randomised controlled trials (ELICIT): protocol for a systematic review of the literature and identification of a core outcome set using a Delphi survey
Gillies, K., Entwistle, V., Treweek, S. P., Fraser, C., Williamson, P. R., & Campbell, M. K. (2015). Evaluation of interventions for informed consent for randomised controlled trials (ELICIT): protocol for a systematic review of the literature and identification of a core outcome set using a Delphi survey. TRIALS, 16. doi:10.1186/s13063-015-1011-8
Telmisartan and Insulin Resistance in HIV (TAILoR): protocol for a dose-ranging phase II randomised open-labelled trial of telmisartan as a strategy for the reduction of insulin resistance in HIVpositive individuals on combination antiretroviral therapy
Pushpakom, S., Taylor, C., Kolamunnage-Dona, R., Spowart, C., Vora, J., Garcia Finana, M., . . . Pirmohamed, M. (2015). Telmisartan and Insulin Resistance in HIV (TAILoR): protocol for a dose-ranging phase II randomised open-labelled trial of telmisartan as a strategy for the reduction of insulin resistance in HIVpositive individuals on combination antiretroviral therapy. BMJ Open, 5(10). doi:10.1136/bmjopen-2015-009566
Consensus on the Need for a Hierarchical List of Patient-reported Pain Outcomes for Metaanalyses of Knee Osteoarthritis Trials: An OMERACT Objective
Christensen, R., Maxwell, L. J., Jueni, P., Tovey, D., Williamson, P. R., Boers, M., . . . Tugwell, P. (2015). Consensus on the Need for a Hierarchical List of Patient-reported Pain Outcomes for Metaanalyses of Knee Osteoarthritis Trials: An OMERACT Objective. JOURNAL OF RHEUMATOLOGY, 42(10), 1971-1975. doi:10.3899/jrheum.141384
Dialogue on Developing Consensus on Measurement and Presentation of Patient-important Outcomes, Using Pain Outcomes as an Exemplar, in Systematic Reviews: A Preconference Meeting at OMERACT 12
Tugwell, P. S., Maxwell, L. J., Beaton, D. E., Busse, J. W., Christensen, R., Conaghan, P. G., . . . Williamson, P. (2015). Dialogue on Developing Consensus on Measurement and Presentation of Patient-important Outcomes, Using Pain Outcomes as an Exemplar, in Systematic Reviews: A Preconference Meeting at OMERACT 12. JOURNAL OF RHEUMATOLOGY, 42(10), 1931-1933. doi:10.3899/jrheum.141430
Development of a core outcome set for research and audit studies in reconstructive breast surgery
Potter, S., Holcombe, C., Ward, J. A., & Blazeby, J. M. (2015). Development of a core outcome set for research and audit studies in reconstructive breast surgery. BRITISH JOURNAL OF SURGERY, 102(11), 1360-1371. doi:10.1002/bjs.9883
Interventions in randomised controlled trials in surgery: issues to consider during trial design
Blencowe, N. S., Brown, J. M., Cook, J. A., Metcalfe, C., Morton, D. G., Nicholl, J., . . . Blazeby, J. M. D. (2015). Interventions in randomised controlled trials in surgery: issues to consider during trial design. TRIALS, 16. doi:10.1186/s13063-015-0918-4
An evidence base to optimise methods for involving patient and public contributors in clinical trials: a mixed-methods study
Gamble, C., Dudley, L., Allam, A., Bell, P., Buck, D., Goodare, H., . . . Young, B. (2015). An evidence base to optimise methods for involving patient and public contributors in clinical trials: a mixed-methods study. Health Services and Delivery Research, 3(39). doi:10.3310/hsdr03390
The management of Otitis Media with Effusion in children with cleft palate (mOMEnt): a feasibility study and economic evaluation
Bruce, I., Harman, N., Williamson, P., Tierney, S., Callery, P., Mohiuddin, S., . . . O'Brien, K. (2015). The management of Otitis Media with Effusion in children with cleft palate (mOMEnt): a feasibility study and economic evaluation. HEALTH TECHNOLOGY ASSESSMENT, 19(68), 1-+. doi:10.3310/hta19680
COS-STAR: a reporting guideline for studies developing core outcome sets (protocol)
Kirkham, J. J., Gorst, S., Altman, D. G., Blazeby, J., Clarke, M., Devane, D., . . . Williamson, P. R. (2015). COS-STAR: a reporting guideline for studies developing core outcome sets (protocol). TRIALS, 16. doi:10.1186/s13063-015-0913-9
Core Outcomes in Ventilation Trials (COVenT): protocol for a core outcome set using a Delphi survey with a nested randomised trial and observational cohort study
Blackwood, B., Ringrow, S., Clarke, M., Marshall, J., Rose, L., Williamson, P., & McAuley, D. (2015). Core Outcomes in Ventilation Trials (COVenT): protocol for a core outcome set using a Delphi survey with a nested randomised trial and observational cohort study. TRIALS, 16. doi:10.1186/s13063-015-0905-9
The Importance of Integration of Stakeholder Views in Core Outcome Set Development: Otitis Media with Effusion in Children with Cleft Palate
Harman, N. L., Bruce, I. A., Kirkham, J. J., Tierney, S., Callery, P., O'Brien, K., . . . Williamson, P. R. (2015). The Importance of Integration of Stakeholder Views in Core Outcome Set Development: Otitis Media with Effusion in Children with Cleft Palate. PLOS ONE, 10(6). doi:10.1371/journal.pone.0129514
Development of an internationally agreed minimal dataset for juvenile dermatomyositis (JDM) for clinical and research use
McCann, L. J., Kirkham, J. J., Wedderburn, L. R., Pilkington, C., Huber, A. M., Ravelli, A., . . . Beresford, M. W. (2015). Development of an internationally agreed minimal dataset for juvenile dermatomyositis (JDM) for clinical and research use. TRIALS, 16. doi:10.1186/s13063-015-0784-0
Core information set for oesophageal cancer surgery
Blazeby, J. M., Macefield, R., Blencowe, N. S., Jacobs, M., McNair, A. G. K., Sprangers, M., & Brookes, S. T. (2015). Core information set for oesophageal cancer surgery. BRITISH JOURNAL OF SURGERY, 102(8), 936-943. doi:10.1002/bjs.9840
What Difference Does Patient and Public Involvement Make and What Are Its Pathways to Impact? Qualitative Study of Patients and Researchers from a Cohort of Randomised Clinical Trials
Dudley, L., Gamble, C., Preston, J., Buck, D., The EPIC Patient Advisory Group., Hanley, B., . . . Young, B. (2015). What Difference Does Patient and Public Involvement Make and What Are Its Pathways to Impact? Qualitative Study of Patients and Researchers from a Cohort of Randomised Clinical Trials. PLOS ONE, 10(6). doi:10.1371/journal.pone.0128817
Making randomised trials more efficient: report of the first meeting to discuss the Trial Forge platform
Treweek, S., Altman, D. G., Bower, P., Campbell, M., Chalmers, I., Cotton, S., . . . Clarke, M. (2015). Making randomised trials more efficient: report of the first meeting to discuss the Trial Forge platform. TRIALS, 16. doi:10.1186/s13063-015-0776-0
24. What outcomes should be measured in reconstructive breast surgery? The BRAVO (Breast Reconstruction and Valid Outcomes) Study
Potter, S., Holcombe, C., Ward, J., Macefield, R., Cawthorn, S., Warr, R., . . . Blazeby, J. (2015). 24. What outcomes should be measured in reconstructive breast surgery? The BRAVO (Breast Reconstruction and Valid Outcomes) Study. European Journal of Surgical Oncology (EJSO), 41(6), S24. doi:10.1016/j.ejso.2015.03.025
DEVELOPMENT OF AN INTERNATIONALLY AGREED MINIMAL DATASET FOR JUVENILE DERMATOMYOSITIS (JDM) FOR CLINICAL AND RESEARCH USE
McCann, L., Wedderburn, L. R., Pilkington, C., Huber, A. M., Ravelli, A., Williamson, P., . . . Beresford, M. W. (2015). DEVELOPMENT OF AN INTERNATIONALLY AGREED MINIMAL DATASET FOR JUVENILE DERMATOMYOSITIS (JDM) FOR CLINICAL AND RESEARCH USE. In ANNALS OF THE RHEUMATIC DISEASES Vol. 74 (pp. 837-838). doi:10.1136/annrheumdis-2015-eular.2479
Towards core outcome set (COS) development: a follow-up descriptive survey of outcomes in Cochrane reviews
Wuytack, F., Smith, V., Clarke, M., Williamson, P., & Gargon, E. (2015). Towards core outcome set (COS) development: a follow-up descriptive survey of outcomes in Cochrane reviews. SYSTEMATIC REVIEWS, 4. doi:10.1186/s13643-015-0060-0
Core outcome sets and trial registries
Clarke, M., & Williamson, P. (2015). Core outcome sets and trial registries. TRIALS, 16. doi:10.1186/s13063-015-0738-6
Multivariate meta-analysis helps examine the impact of outcome reporting bias in Cochrane rheumatoid arthritis reviews
Frosi, G., Riley, R. D., Williamson, P. R., & Kirkham, J. J. (2015). Multivariate meta-analysis helps examine the impact of outcome reporting bias in Cochrane rheumatoid arthritis reviews. JOURNAL OF CLINICAL EPIDEMIOLOGY, 68(5), 542-550. doi:10.1016/j.jclinepi.2014.11.017
A little more conversation please? Qualitative study of researchers’ and patients’ interview accounts of training for patient and public involvement in clinical trials
Dudley, L., Gamble, C., Allam, A., Bell, P., Buck, D., Goodare, H., . . . Young, B. (2015). A little more conversation please? Qualitative study of researchers’ and patients’ interview accounts of training for patient and public involvement in clinical trials. Trials, 16. doi:10.1186/s13063-015-0667-4
Prokinetics Prescribing in Paediatrics: Evidence on Cisapride, Domperidone, and Metoclopramide
Mt-Isa, S., Tomlin, S., Sutcliffe, A., Underwood, M., Williamson, P., Croft, N. M., & Ashby, D. (2015). Prokinetics Prescribing in Paediatrics: Evidence on Cisapride, Domperidone, and Metoclopramide. JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION, 60(4), 508-514. doi:10.1097/MPG.0000000000000657
Collating the knowledge base for core outcome set development: developing and appraising the search strategy for a systematic review
Gargon, E., Williamson, P. R., & Clarke, M. (2015). Collating the knowledge base for core outcome set development: developing and appraising the search strategy for a systematic review. BMC MEDICAL RESEARCH METHODOLOGY, 15. doi:10.1186/s12874-015-0019-9
A core outcome set for localised prostate cancer effectiveness trials: protocol for a systematic review of the literature and stakeholder involvement through interviews and a Delphi survey
MacLennan, S., Bekema, H. J., Williamson, P. R., Campbell, M. K., Stewart, F., MacLennan, S. J., . . . Lam, T. B. L. (2015). A core outcome set for localised prostate cancer effectiveness trials: protocol for a systematic review of the literature and stakeholder involvement through interviews and a Delphi survey. TRIALS, 16. doi:10.1186/s13063-015-0598-0
Survey of new 2007 and 2011 Cochrane reviews found 37% of prespecified outcomes not reported
Smith, V., Clarke, M., Williamson, P., & Gargon, E. (2015). Survey of new 2007 and 2011 Cochrane reviews found 37% of prespecified outcomes not reported. JOURNAL OF CLINICAL EPIDEMIOLOGY, 68(3), 237-245. doi:10.1016/j.jclinepi.2014.09.022
Core outcome sets for use in effectiveness trials involving people with bipolar and schizophrenia in a community-based setting (PARTNERS2): study protocol for the development of two core outcome sets
Keeley, T., Khan, H., Pinfold, V., Williamson, P., Mathers, J., Davies, L., . . . Calvert, M. (2015). Core outcome sets for use in effectiveness trials involving people with bipolar and schizophrenia in a community-based setting (PARTNERS2): study protocol for the development of two core outcome sets. TRIALS, 16. doi:10.1186/s13063-015-0553-0
RE: Recommended Patient-Reported Core Set of Symptoms to Measure in Adult Cancer Treatment Trials
Main, B. G., Blencowe, N., Williamson, P. R., & Blazeby, J. M. (2015). RE: Recommended Patient-Reported Core Set of Symptoms to Measure in Adult Cancer Treatment Trials. JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE, 107(4). doi:10.1093/jnci/dju506
The natural history of conducting and reporting clinical trials: interviews with trialists
Smyth, R., Jacoby, A., Altman, D. G., Gamble, C., & Williamson, P. (2015). The natural history of conducting and reporting clinical trials: interviews with trialists. Trials, 16. doi:10.1186/s13063-014-0536-6
A mixed methods study of researchers’ experiences of developing core outcome sets
Gargon, E., Young, B., & Williamson, P. (2015). A mixed methods study of researchers’ experiences of developing core outcome sets. Trials, 16(Suppl 2), P60.
A review of the description of patient withdrawal in trial protocols and patient information sheets (PIS)
Kearney, A., Daykin, A., Heawood, A., Lane, A., Blazeby, J., Clarke, M., . . . Gamble, C. (2015). A review of the description of patient withdrawal in trial protocols and patient information sheets (PIS). Trials, 16(Suppl 2), P46.
A survey of core outcome set developers
Gargon, E., Young, B., & Williamson, P. R. (2015). A survey of core outcome set developers. In TRIALS Vol. 16. doi:10.1186/1745-6215-16-S1-O1
Abstracts of the 4th Meeting of the Core Outcome Measures in Effectiveness Trials (COMET) Initiative.
Abstracts of the 4th Meeting of the Core Outcome Measures in Effectiveness Trials (COMET) Initiative. (2015). Trials, 16 Suppl 1, M1-P36. doi:10.1186/1745-6215-16-s1-m1
Are patients and health care professionals influenced by each other's’ opinions about the outcomes to measure in localised prostate cancer effectiveness trials?
MacLennan, S., Lam, T., & Williamson, P. (2015). Are patients and health care professionals influenced by each other's’ opinions about the outcomes to measure in localised prostate cancer effectiveness trials?. Trials, 16(Suppl 2), P64.
COMET IV meeting summary
Gargon, E., Altman, D. G., Blazeby, J. M., Clarke, M., & Williamson, P. R. (2015). COMET IV meeting summary. TRIALS, 16. doi:10.1186/1745-6215-16-S1-M1
Choosing important health outcomes for comparative effectiveness research: an updated review and user survey
Gorst, S. L., Gargon, E., & Williamson, P. R. (2015). Choosing important health outcomes for comparative effectiveness research: an updated review and user survey. Trials, 16(Suppl 3), P8.
Citation analysis: a new approach to assess the uptake of core outcome sets
Barnes, K., Clarke, M., Kirkham, J., & Williamson, P. (2015). Citation analysis: a new approach to assess the uptake of core outcome sets. Trials, 16(Suppl 2), P50.
Common antiepileptic drugs in pregnancy in women with epilepsy (Withdrawn Paper 2015, art no CD004848)
Adab, N., Smith, C. T., Vinten, J., Williamson, P. R., Winterbottom, J. B., Mckay, A. J., & Bromley, R. (2015). Common antiepileptic drugs in pregnancy in women with epilepsy (Withdrawn Paper 2015, art no CD004848). COCHRANE DATABASE OF SYSTEMATIC REVIEWS, (12). Retrieved from https://www.webofscience.com/
Consensus on the need for a hierarchical list of patient-reported pain outcomes for meta-analyses of knee osteoarthritis trials
Klokker, L., Maxwell, L. J., Juni, P., Tovey, D., Williamson, P. R., Boers, M., . . . Christensen, R. (2015). Consensus on the need for a hierarchical list of patient-reported pain outcomes for meta-analyses of knee osteoarthritis trials. In TRIALS Vol. 16. doi:10.1186/1745-6215-16-S1-P36
Developing a toolkit for patient and public involvement in a clinical trials unit
Bagley, H., Harman, N., Woolfall, K., Young, B., Short, H., Hickey, H., & Williamson, P. (2015). Developing a toolkit for patient and public involvement in a clinical trials unit. Trials, 16(Suppl 2), O92.
Development and evaluation of an electronic diary for recording patient reported outcomes in the overt study
Appelbe, D., Adeogun, O., Webb, N., Majeed, R., Lewis, M., & Williamson, P. (2015). Development and evaluation of an electronic diary for recording patient reported outcomes in the overt study. Trials, 16(Suppl 2), O64.
Development of an Internationally Agreed Minimal Dataset for Juvenile Dermatomyositis (JDM) for Clinical and Research Use
McCann, L. J., Wedderburn, L. R., Pilkington, C., Huber, A. M., Ravelli, A., Kirkham, J., . . . Beresford, M. W. (2015). Development of an Internationally Agreed Minimal Dataset for Juvenile Dermatomyositis (JDM) for Clinical and Research Use. ARTHRITIS & RHEUMATOLOGY, 67. Retrieved from https://www.webofscience.com/
Development of an online resource for recruitment research in clinical trials (ORRCA)
Harman, N., Treweek, S., Clarke, M., Williamson, P., Bower, P., & Gamble, C. (2015). Development of an online resource for recruitment research in clinical trials (ORRCA). Trials, 16(Suppl 2), P98.
Development of guidance for statistical analysis plans (SAPs) for clinical trials
Krishan, A., Stocken, D., Lewis, S., Juszczak, E., Dore, C., Williamson, P., . . . Gamble, C. (2015). Development of guidance for statistical analysis plans (SAPs) for clinical trials. Trials, 16(Suppl 2), O41.
EvaLuation of Interventions for informed Consent for randomised controlled Trials (ELICIT): developing a core outcome set
Gillies, K., Fraser, C., Entwistle, V., Treweek, S., Williamson, P., & Campbell, M. (2015). EvaLuation of Interventions for informed Consent for randomised controlled Trials (ELICIT): developing a core outcome set. In TRIALS Vol. 16. doi:10.1186/1745-6215-16-S1-P5
Evaluation of interventions for informed consent for randomised controlled trials (ELICIT): developing a core outcome set
Gillies, K., Fraser, C., Entwistle, V., Treweek, S., Williamson, P., & Campbell, M. (2015). Evaluation of interventions for informed consent for randomised controlled trials (ELICIT): developing a core outcome set. Trials, 16(Suppl 2), P53.
Good practice principles for sharing individual participant data from publicly funded clinical trials
Smith, C. T., Hopkins, C., Sydes, M., Woolfall, K., Clarke, M., Murray, G., & Williamson, P. (2015). Good practice principles for sharing individual participant data from publicly funded clinical trials. TRIALS, 16. doi:10.1186/1745-6215-16-S2-O1
Joint modelling of longitudinal and time-to-event data
Powney, M. (2015). Joint modelling of longitudinal and time-to-event data.
Optimising the design of internal pilot work to inform efficient randomised controlled trials: issues to consider when developing progression criteria
Avery, K., Williamson, P., Gamble, C., Francischetto, E. O., Metcalfe, C., Davidson, P., & Blazeby, J. (2015). Optimising the design of internal pilot work to inform efficient randomised controlled trials: issues to consider when developing progression criteria. Trials, 16(Suppl 2), P10.
PARTNERS2: a protocol for the development of a core outcome set for use in mental health trials involving people with schizophrenia or bipolar disorder in a community setting
Keeley, T., Khan, H., Pinfold, V., Williamson, P., Mathers, J., Davies, L., . . . Calvert, M. (2015). PARTNERS2: a protocol for the development of a core outcome set for use in mental health trials involving people with schizophrenia or bipolar disorder in a community setting. In TRIALS Vol. 16. doi:10.1186/1745-6215-16-S1-P28
Pragmatic approaches to mitigating missing data and research priorities to assess the effectiveness of interventions
Kearney, A., Daykin, A., Heawood, A., Lane, A., Blazeby, J., Clarke, M., . . . Gamble, C. (2015). Pragmatic approaches to mitigating missing data and research priorities to assess the effectiveness of interventions. Trials, 16(Suppl 2), P238.
Re: Neil E. Martin, Laura Massey, Caleb Stowell, et al. Defining a Standard Set of Patient-centered Outcomes for Men with Localized Prostate Cancer. Eur Urol 2015; 67: 460-7
MacLennan, S., Williamson, P. R., & Lam, T. B. (2015). Re: Neil E. Martin, Laura Massey, Caleb Stowell, et al. Defining a Standard Set of Patient-centered Outcomes for Men with Localized Prostate Cancer. Eur Urol 2015; 67: 460-7. EUROPEAN UROLOGY, 68(6), E123-E124. doi:10.1016/j.eururo.2015.08.015
Realising the potential of patient and public involvement to make a difference: what can trial teams do?
Young, B., Dudley, L., Williamson, P., & Gamble, C. (2015). Realising the potential of patient and public involvement to make a difference: what can trial teams do?. Trials, 16(Suppl 2), O93.
Recruitment progression rules for internal pilot studies monitoring recruitment
Hampson, L., Williamson, P., Wilby, M., & Jaki, T. (2015). Recruitment progression rules for internal pilot studies monitoring recruitment. Trials, 16(Suppl 2), O89.
Reported reasons for missing data and the interplay with trial setting
Kearney, A., Bacon, N., Rosala-Hallas, A., Daykin, A., Heawood, A., Lane, A., . . . Gamble, C. (2015). Reported reasons for missing data and the interplay with trial setting. Trials, 16(Suppl 2), P101.
Selective reporting in clinical trials - an examination of discrepancy rates in pre-specified and reported outcomes in articles submitted to the BMJ
Weston, J., Dwan, K., Altman, D., Clarke, M., Gamble, C., Groves, T., . . . Kirkham, J. (2015). Selective reporting in clinical trials - an examination of discrepancy rates in pre-specified and reported outcomes in articles submitted to the BMJ. Trials, 16(Suppl 2), O72.
The Patient and Public Involvement Activities of the COMET Initiative
Bagley, H., Young, B., & Williamson, P. R. (2015). The Patient and Public Involvement Activities of the COMET Initiative. Trials, 16(Suppl 3), P7.
The core outcome measures in effectiveness trials (COMET) initiative: five years on
Williamson, P., Altman, D., Blazeby, J., Clarke, M., Gargon, E., Gorst, S., & Tunis, S. (2015). The core outcome measures in effectiveness trials (COMET) initiative: five years on. Trials, 16(Suppl 2), P69.
The need for standardised outcomes in cancer clinical trials: a report of cancer core outcome sets
Gargon, E., Altman, D., Blazeby, J., Clarke, M., & Williamson, P. (2015). The need for standardised outcomes in cancer clinical trials: a report of cancer core outcome sets. EUROPEAN JOURNAL OF CANCER CARE, 24, 10. Retrieved from https://www.webofscience.com/
The trials and tribulations of accessing data from routine sources
Powell, G., Marson, T., Hughes, D., Williamson, P., & Tudur-Smith, C. (2015). The trials and tribulations of accessing data from routine sources. In TRIALS Vol. 16. doi:10.1186/1745-6215-16-S2-P225
Three nested RCTs of dual or single stakeholder feedback within Delphi surveys during core outcome and information set development
Brookes, S., Macefield, R., Williamson, P., McNair, A., Potter, S., Blencowe, N., . . . Blazeby, J. (2015). Three nested RCTs of dual or single stakeholder feedback within Delphi surveys during core outcome and information set development. Trials, 16(Suppl 2), P51.
Using qualitative research to understand what outcomes matter to patients: direct and indirect approaches to outcome elicitation
Mathers, J., Keeley, T., Jones, L., Calvert, M., Williamson, P., Jones, J., . . . Young, B. (2015). Using qualitative research to understand what outcomes matter to patients: direct and indirect approaches to outcome elicitation. Trials, 16(Suppl 2), O39.
2014
From plans to actions in patient and public involvement: qualitative study of documented plans and the accounts of researchers and patients sampled from a cohort of clinical trials
Buck, D., Gamble, C., Dudley, L., Preston, J., Hanley, B., Williamson, P., . . . The EPIC Patient Advisory Group. (2014). From plans to actions in patient and public involvement: qualitative study of documented plans and the accounts of researchers and patients sampled from a cohort of clinical trials. BMJ Open, 4(12). doi:10.1136/bmjopen-2014-006400
Selective reporting bias of harm outcomes within studies: findings from a cohort of systematic reviews
Saini, P., Loke, Y. K., Gamble, C., Altman, D. G., Williamson, P., & Kirkham, J. (2014). Selective reporting bias of harm outcomes within studies: findings from a cohort of systematic reviews. BMJ: British Medical Journal, 349(7985). doi:10.1136/bmj.g6501
CHOOSING IMPORTANT HEALTH OUTCOMES FOR COMPARATIVE EFFECTIVENESS RESEARCH: A SYSTEMATIC REVIEW
Gargon, E., Gurung, B., Medley, N., Altman, D., Blazeby, J., Clarke, M., & Williamson, P. (2014). CHOOSING IMPORTANT HEALTH OUTCOMES FOR COMPARATIVE EFFECTIVENESS RESEARCH: A SYSTEMATIC REVIEW. VALUE IN HEALTH, 17(7), A435. doi:10.1016/j.jval.2014.08.1118
Interventions to improve recruitment and retention in clinical trials: a survey and workshop to assess current practice and future priorities
Bower, P., Brueton, V., Gamble, C., Treweek, S., Smith, C. T., Young, B., & Williamson, P. (2014). Interventions to improve recruitment and retention in clinical trials: a survey and workshop to assess current practice and future priorities. TRIALS, 15. doi:10.1186/1745-6215-15-399
ECONOMIC EVALUATION OF NEBULIZED MAGNESIUM SULPHATE IN ACUTE SEVERE ASTHMA IN CHILDREN
Petrou, S., Boland, A., Khan, K., Powell, C., Kolamunnage-Dona, R., Lowe, J., . . . Williamson, P. (2014). ECONOMIC EVALUATION OF NEBULIZED MAGNESIUM SULPHATE IN ACUTE SEVERE ASTHMA IN CHILDREN. INTERNATIONAL JOURNAL OF TECHNOLOGY ASSESSMENT IN HEALTH CARE, 30(4), 354-360. doi:10.1017/S0266462314000440
Opening research sites in multicentre clinical trials within the UK: a detailed analysis of delays
Kearney, A., McKay, A., Hickey, H., Balabanova, S., Marson, A. G., Gamble, C., & Williamson, P. (2014). Opening research sites in multicentre clinical trials within the UK: a detailed analysis of delays. BMJ OPEN, 4(9). doi:10.1136/bmjopen-2014-005874
Opening research sites in multicentre clinical trials within the UK: a detailed analysis of delays
Kearney, A., McKay, A., Hickey, H., Balabanova, S., Marson, A. G., Gamble, C., & Williamson, P. (2014). Opening research sites in multicentre clinical trials within the UK: a detailed analysis of delays. BMJ Open, 4(9). doi:10.1136/bmjopen-2014-005874
It's time to agree on standard and clinically important primary outcomes
Scott, J. (2014). It's time to agree on standard and clinically important primary outcomes. BJOG: An International Journal of Obstetrics & Gynaecology, 121(10), 1195. doi:10.1111/1471-0528.12590
Patient and public involvement in the early stages of clinical trial development: a systematic cohort investigation
Gamble, C., Dudley, L., Allam, A., Bell, P., Goodare, H., Hanley, B., . . . Young, B. (2014). Patient and public involvement in the early stages of clinical trial development: a systematic cohort investigation. BMJ Open, 4(7). doi:10.1136/bmjopen-2014-005234
The COMET Initiative database: progress and activities from 2011 to 2013
Gargon, E., Williamson, P. R., Altman, D. G., Blazeby, J. M., & Clarke, M. (2014). The COMET Initiative database: progress and activities from 2011 to 2013. TRIALS, 15. doi:10.1186/1745-6215-15-279
A review of the handling of missing longitudinal outcome data in clinical trials
Powney, M., Williamson, P., Kirkham, J., & Kolamunnage-Dona, R. (2014). A review of the handling of missing longitudinal outcome data in clinical trials. Trials, 15. doi:10.1186/1745-6215-15-237
Choosing Important Health Outcomes for Comparative Effectiveness Research: A Systematic Review
Gargon, E., Gurung, B., Medley, N., Altman, D. G., Blazeby, J. M., Clarke, M., & Williamson, P. R. (2014). Choosing Important Health Outcomes for Comparative Effectiveness Research: A Systematic Review. PLOS ONE, 9(6). doi:10.1371/journal.pone.0099111
Sharing Individual Participant Data from Clinical Trials: An Opinion Survey Regarding the Establishment of a Central Repository
Tudur Smith, C., Dwan, K., Altman, D. G., Clarke, M., Riley, R., & Williamson, P. R. (2014). Sharing Individual Participant Data from Clinical Trials: An Opinion Survey Regarding the Establishment of a Central Repository. PLoS One, 9(5). doi:10.1371/journal.pone.0097886
Time to 12-month remission and treatment failure for generalised and unclassified epilepsy
Bonnett, L., Tudur Smith, C., Smith, D., Williamson, P., Chadwick, D., & Marson, T. (2014). Time to 12-month remission and treatment failure for generalised and unclassified epilepsy. Journal of Neurology, Neurosurgery & Psychiatry, 85(6), 603-610. doi:10.1136/jnnp-2013-306040
Risk-proportionate clinical trial monitoring: an example approach from a non-commercial trials unit
Smith, C. T., Williamson, P., Jones, A., Smyth, A., Hewer, S. L., & Gamble, C. (2014). Risk-proportionate clinical trial monitoring: an example approach from a non-commercial trials unit. TRIALS, 15. doi:10.1186/1745-6215-15-127
A model-based correction for outcome reporting bias in meta-analysis
Copas, J., Dwan, K., Kirkham, J., & Williamson, P. (2014). A model-based correction for outcome reporting bias in meta-analysis. BIOSTATISTICS, 15(2), 370-383. doi:10.1093/biostatistics/kxt046
The UK Lung Screen (UKLS): Demographic Profile of First 88,897 Approaches Provides Recommendations for Population Screening
McRonald, F. E., Yadegarfar, G., Baldwin, D. R., Devaraj, A., Brain, K. E., Eisen, T., . . . Field, J. K. (2014). The UK Lung Screen (UKLS): Demographic Profile of First 88,897 Approaches Provides Recommendations for Population Screening. CANCER PREVENTION RESEARCH, 7(3), 362-371. doi:10.1158/1940-6207.CAPR-13-0206
The Trials Methodological Research Agenda: Results from a priority setting exercise.
Tudur Smith, C., Hickey, H., Clarke, M., Blazeby, J., & Williamson, P. R. (2014). The Trials Methodological Research Agenda: Results from a priority setting exercise.. Trials, 15. Retrieved from https://trialsjournal.biomedcentral.com/articles/10.1186/1745-6215-15-32
The trials methodological research agenda: results from a priority setting exercise
Smith, C. T., Hickey, H., Clarke, M., Blazeby, J., & Williamson, P. (2014). The trials methodological research agenda: results from a priority setting exercise. TRIALS, 15. doi:10.1186/1745-6215-15-32
ADRIC: Adverse Drug Reactions In Children – a programme of research using mixed methods
Smyth, R. L., Peak, M., Turner, M. A., Nunn, A. J., Williamson, P. R., Young, B., . . . Pirmohamed, M. (2014). ADRIC: Adverse Drug Reactions In Children – a programme of research using mixed methods.
AMIPROM (Amnioinfusion in very early preterm prelabor rupture of membranes): pregnancy, neonatal and maternal outcomes in a randomized controlled pilot study.
Roberts, D., Vause, S., Martin, W., Green, P., Walkinshaw, S., Bricker, L., . . . Alfirevic, Z. (2014). AMIPROM (Amnioinfusion in very early preterm prelabor rupture of membranes): pregnancy, neonatal and maternal outcomes in a randomized controlled pilot study.. Ultrasound Obstet Gynecol.
Amnioinfusion in preterm premature rupture of membranes (AMIPROM): a randomised controlled trial of amnioinfusion versus expectant management in very early preterm premature rupture of membranes - a pilot study
Roberts, D., Vause, S., Martin, W., Green, P., Walkinshaw, S., Bricker, L., . . . Alfirevic, Z. (2014). Amnioinfusion in preterm premature rupture of membranes (AMIPROM): a randomised controlled trial of amnioinfusion versus expectant management in very early preterm premature rupture of membranes - a pilot study. HEALTH TECHNOLOGY ASSESSMENT, 18(21), 1-+. doi:10.3310/hta18210
Amnioinfusion in preterm premature rupture of membranes (AMIPROM): a randomised controlled trial of amnioinfusion versus expectant management in very early preterm premature rupture of membranes - a pilot study.
Roberts, D., Vause, S., Martin, W., Green, P., Walkinshaw, S., Bricker, L., . . . Alfirevic, Z. (2014). Amnioinfusion in preterm premature rupture of membranes (AMIPROM): a randomised controlled trial of amnioinfusion versus expectant management in very early preterm premature rupture of membranes - a pilot study.. HTA.
Amnioinfusion in very early preterm prelabor rupture of membranes (AMIPROM): pregnancy, neonatal and maternal outcomes in a randomized controlled pilot study
Roberts, D., Vause, S., Martin, W., Green, P., Walkinshaw, S., Bricker, L., . . . Alfirevic, Z. (2014). Amnioinfusion in very early preterm prelabor rupture of membranes (AMIPROM): pregnancy, neonatal and maternal outcomes in a randomized controlled pilot study. ULTRASOUND IN OBSTETRICS & GYNECOLOGY, 43(05), 490-499. doi:10.1002/uog.13258
Choosing Important Health Outcomes for Comparative Effectiveness Research: A Systematic Review
Gargon, E., Gurung, B., Medley, N., Altman, D. G., Blazeby, J. M., Clarke, M., & Williamson, P. R. (n.d.). Choosing Important Health Outcomes for Comparative Effectiveness Research: A Systematic Review. PLoS ONE, 9(6), e99111. doi:10.1371/journal.pone.0099111
Core outcome sets will improve the quality of obstetrics research
Williamson, P. (2014). Core outcome sets will improve the quality of obstetrics research. BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY, 121(10), 1196. doi:10.1111/1471-0528.12591
Economic evaluation of nebulized MgSO4 in childhood acute severe asthma
Petrou, S., & al, E. (2014). Economic evaluation of nebulized MgSO4 in childhood acute severe asthma. International Journal of Technology Assessment in Health Care.
Evidence for the selective reporting of analyses and discrepancies in clinical trials: a systematic review of cohort studies of clinical trials
Dwan, K., Altman, D. G., Clarke, M., Gamble, C., Higgins, J. P. T., Sterne, J. A. C., . . . Kirkham, J. J. (n.d.). Evidence for the selective reporting of analyses and discrepancies in clinical trials: a systematic review of cohort studies of clinical trials. PLoS Medicine, 11(6). doi:10.1371/journal.pmed.1001666
Methodology of clinical trials for rare diseases
Smith, C. T., Williamson, P. R., & Beresford, M. W. (2014). Methodology of clinical trials for rare diseases. BEST PRACTICE & RESEARCH IN CLINICAL RHEUMATOLOGY, 28(2), 247-262. doi:10.1016/j.berh.2014.03.004
Methodology of clinical trials for rare diseases
Tudur Smith, C., Williamson, P. R., & Beresford, M. W. (2014). Methodology of clinical trials for rare diseases. Best Practice and Research: Clinical Rheumatology, 28(2), 247-262. doi:10.1016/j.berh.2014.03.004
News feature about the COMET Initiative
Keener. (2014). News feature about the COMET Initiative. Nature Medicine. Retrieved from http://www.nature.com/nm/journal/v20/n8/full/nm0814-798.html
Statistical Power of Multilevel Modelling in Dental Caries Clinical Trials: A Simulation Study
Burnside, G., Pine, C. M., & Williamson, P. R. (2014). Statistical Power of Multilevel Modelling in Dental Caries Clinical Trials: A Simulation Study. CARIES RESEARCH, 48(1), 13-18. doi:10.1159/000351642
The UK Lung Screen (UKLS): demographic profile of first 88,897 approaches provides recommendations for population screening
McRonald, F. E., Yadegarfar, G., Baldwin, D. R., Devaraj, A., Brain, K. E., Eisen, T., . . . Field, J. K. (2014). The UK Lung Screen (UKLS): demographic profile of first 88,897 approaches provides recommendations for population screening. Cancer Prev Res.
Trial design for rare paediatric diseases
Tudur Smith, C., Williamson, P. R., & Beresford, M. W. (2014). Trial design for rare paediatric diseases. Best Practice & Research Clinical Rheumatology.
2013
A Randomized Trial of Genotype-Guided Dosing of Warfarin
Pirmohamed, M., Burnside, G., Eriksson, N., Jorgensen, A. L., Toh, C. H., Nicholson, T., . . . Wadelius, M. (2013). A Randomized Trial of Genotype-Guided Dosing of Warfarin. New England Journal of Medicine, 369(24), 2294-2303. doi:10.1056/nejmoa1311386
A Randomized Trial of Genotype-Guided Dosing of Warfarin
Pirmohamed, M., Burnside, G., Eriksson, N., Jorgensen, A. L., Toh, C. H., Nicholson, T., . . . Wadelius, M. (2013). A Randomized Trial of Genotype-Guided Dosing of Warfarin. NEW ENGLAND JOURNAL OF MEDICINE, 369(24), 2294-2303. doi:10.1056/NEJMoa1311386
Assessing key assumptions of network meta-analysis: a review of methods
Donegan, S., Williamson, P., D'Alessandro, U., & Smith, C. T. (2013). Assessing key assumptions of network meta-analysis: a review of methods. RESEARCH SYNTHESIS METHODS, 4(4), 291-323. doi:10.1002/jrsm.1085
Incidence, characteristics and risk factors of adverse drug reactions in hospitalized children - a prospective observational cohort study of 6,601 admissions
Thiesen, S., Conroy, E. J., Bellis, J. R., Bracken, L. E., Mannix, H. L., Bird, K. A., . . . Smyth, R. L. (2013). Incidence, characteristics and risk factors of adverse drug reactions in hospitalized children - a prospective observational cohort study of 6,601 admissions. BMC MEDICINE, 11. doi:10.1186/1741-7015-11-237
PATIENT PREFERENCES AND PRIORITIES FOR ANTI-EPILEPTIC DRUG TREATMENT
Fargher, E. A., Marson, A., Jacoby, A., Ring, A., Williamson, P., & Hughes, D. A. (2013). PATIENT PREFERENCES AND PRIORITIES FOR ANTI-EPILEPTIC DRUG TREATMENT. VALUE IN HEALTH, 16(7), A626. doi:10.1016/j.jval.2013.08.1845
Outcome measures in rheumatoid arthritis randomised trials over the last 50 years
Kirkham, J. J., Boers, M., Tugwell, P., Clarke, M., & Williamson, P. R. (2013). Outcome measures in rheumatoid arthritis randomised trials over the last 50 years. TRIALS, 14. doi:10.1186/1745-6215-14-324
Systematic Review of the Empirical Evidence of Study Publication Bias and Outcome Reporting Bias - An Updated Review
Dwan, K., Gamble, C., Williamson, P. R., & Kirkham, J. J. (2013). Systematic Review of the Empirical Evidence of Study Publication Bias and Outcome Reporting Bias - An Updated Review. PLOS ONE, 8(7). doi:10.1371/journal.pone.0066844
Parents' Agendas in Paediatric Clinical Trial Recruitment Are Different from Researchers' and Often Remain Unvoiced: A Qualitative Study
Woolfall, K., Shilling, V., Hickey, H., Smyth, R. L., Sowden, E., Williamson, P. R., & Young, B. (2013). Parents' Agendas in Paediatric Clinical Trial Recruitment Are Different from Researchers' and Often Remain Unvoiced: A Qualitative Study. PLOS ONE, 8(7). doi:10.1371/journal.pone.0067352
Selective reporting of outcomes in randomised controlled trials in systematic reviews of cystic fibrosis
Dwan, K., Kirkham, J. J., Williamson, P. R., & Gamble, C. (2013). Selective reporting of outcomes in randomised controlled trials in systematic reviews of cystic fibrosis. BMJ OPEN, 3(6). doi:10.1136/bmjopen-2013-002709
Magnesium sulphate in acute severe asthma in children (MAGNETIC): a randomised, placebo-controlled trial
Powell, C., Kolamunnage-Dona, R., Lowe, J., Boland, A., Petrou, S., Doull, I., . . . Williamson, P. (2013). Magnesium sulphate in acute severe asthma in children (MAGNETIC): a randomised, placebo-controlled trial. LANCET RESPIRATORY MEDICINE, 1(4), 301-308. doi:10.1016/S2213-2600(13)70037-7
Barriers to recruitment for surgical trials in head and neck oncology: a survey of trial investigators
Kaur, G., Hutchison, I., Mehanna, H., Williamson, P., Shaw, R., & Smith, C. T. (2013). Barriers to recruitment for surgical trials in head and neck oncology: a survey of trial investigators. BMJ OPEN, 3(4). doi:10.1136/bmjopen-2013-002625
United Kingdom lung cancer screening trial (UKLS): First 88897 approaches.
Field, J. K., Baldwin, D., Devaraj, A., Brain, K., Eisen, T., Holemans, J., . . . Duffy, S. W. (2013). United Kingdom lung cancer screening trial (UKLS): First 88897 approaches.. In CANCER RESEARCH Vol. 73. doi:10.1158/1538-7445.AM2013-3631
4.1 AMIPROM: A Pilot RCT on Serial Transabdominal Amnioinfusion Versus Expectant Management in Very Early PROM (ISRCTN 8192589)
Roberts, D., Vause, S., Martin, W., Green, P., Walkinshaw, S. A., Bricker, L., . . . Alfirevic, Z. (2013). 4.1 AMIPROM: A Pilot RCT on Serial Transabdominal Amnioinfusion Versus Expectant Management in Very Early PROM (ISRCTN 8192589). Archives of Disease in Childhood - Fetal and Neonatal Edition, 98(Suppl 1), A3.3-A4. doi:10.1136/archdischild-2013-303966.010
The use of systematic reviews in the planning, design and conduct of randomised trials: a retrospective cohort of NIHR HTA funded trials
Jones, A. P., Conroy, E., Williamson, P. R., Clarke, M., & Gamble, C. (2013). The use of systematic reviews in the planning, design and conduct of randomised trials: a retrospective cohort of NIHR HTA funded trials. BMC MEDICAL RESEARCH METHODOLOGY, 13. doi:10.1186/1471-2288-13-50
Combining individual patient data and aggregate data in mixed treatment comparison meta-analysis: Individual patient data may be beneficial if only for a subset of trials
Donegan, S., Williamson, P., D'Alessandro, U., Garner, P., & Smith, C. T. (2013). Combining individual patient data and aggregate data in mixed treatment comparison meta-analysis: Individual patient data may be beneficial if only for a subset of trials. STATISTICS IN MEDICINE, 32(6), 914-930. doi:10.1002/sim.5584
The Role of Systematic Reviews in Pharmacovigilance Planning and Clinical Trials Authorisation Application: Example from the SLEEPS Trial
Gamble, C., Wolf, A., Sinha, I., Spowart, C., & Williamson, P. (2013). The Role of Systematic Reviews in Pharmacovigilance Planning and Clinical Trials Authorisation Application: Example from the SLEEPS Trial. PLOS ONE, 8(3). doi:10.1371/journal.pone.0051787
MOMENT - Management of Otitis Media with Effusion in Cleft Palate: protocol for a systematic review of the literature and identification of a core outcome set using a Delphi survey
Harman, N. L., Bruce, I. A., Callery, P., Tierney, S., Sharif, M. O., O'Brien, K., & Williamson, P. R. (2013). MOMENT - Management of Otitis Media with Effusion in Cleft Palate: protocol for a systematic review of the literature and identification of a core outcome set using a Delphi survey. TRIALS, 14. doi:10.1186/1745-6215-14-70
A multistate modelling approach for pancreatic cancer development in genetically high-risk families
Kolamunnage-Dona, R., Vitone, L., Greenhalf, W., Henderson, R., & Williamson, P. R. (2013). A multistate modelling approach for pancreatic cancer development in genetically high-risk families. JOURNAL OF THE ROYAL STATISTICAL SOCIETY SERIES C-APPLIED STATISTICS, 62(2), 201-212. doi:10.1111/j.1467-9876.2012.01051.x
Encephalitis in children: which outcome measures are important?
Lemon, J., Cooper, J., Backman, R., Defres, S., Williamson, P., Kneen, R., & Solomon, T. (n.d.). Encephalitis in children: which outcome measures are important?. Poster session presented at the meeting of COMET 2013.
Management of Asthma in School age Children On Therapy (MASCOT): a randomised, double-blind, placebo-controlled, parallel study of efficacy and safety Introduction
Lenney, W., McKay, A. J., Smith, C. T., Williamson, P. R., James, M., & Price, D. (2013). Management of Asthma in School age Children On Therapy (MASCOT): a randomised, double-blind, placebo-controlled, parallel study of efficacy and safety Introduction. HEALTH TECHNOLOGY ASSESSMENT, 17(4), 1-+. doi:10.3310/hta17040
New European Union regulation of clinical trials is conflicting on deferred consent in emergency situations
Gamble, C., Woolfall, K., Williamson, P., Appleton, R., & Young, B. (2013). New European Union regulation of clinical trials is conflicting on deferred consent in emergency situations. BMJ-BRITISH MEDICAL JOURNAL, 346. doi:10.1136/bmj.f667
Can a core outcome set improve the quality of systematic reviews? - a survey of the Co-ordinating Editors of Cochrane review groups
Kirkham, J. J., Gargon, E., Clarke, M., & Williamson, P. R. (2013). Can a core outcome set improve the quality of systematic reviews? - a survey of the Co-ordinating Editors of Cochrane review groups. TRIALS, 14. doi:10.1186/1745-6215-14-21
A Randomized Trial Comparing Genotype-Guided Dosing of Warfarin to Standard Dosing: The EU Pharmacogenetics of Anticoagulant Therapy (EU-PACT) Warfarin Study
Pirmohamed, M., Burnside, G., Stoddern, J., Prince, C., Toh, C. H., Nicholson, T., . . . Wadelius, M. (2013). A Randomized Trial Comparing Genotype-Guided Dosing of Warfarin to Standard Dosing: The EU Pharmacogenetics of Anticoagulant Therapy (EU-PACT) Warfarin Study. CIRCULATION, 128(24), 2710-2711. Retrieved from https://www.webofscience.com/
A mapping and gapping analysis of patient and public involvement in a clinical trials unit
Bagley, H., Williamson, P., & Gamble, C. (2013). A mapping and gapping analysis of patient and public involvement in a clinical trials unit. Trials, 14(Suppl 1), P93. doi:10.1186/1745-6215-14-s1-p93
A review of recruitment of children to randomised clinical trials in the NIHR clinical research network portfolio
Kaur, G., Smyth, R., & Williamson, P. (2013). A review of recruitment of children to randomised clinical trials in the NIHR clinical research network portfolio. Trials, 14(Suppl 1), P84. doi:10.1186/1745-6215-14-s1-p84
A survey of facilitators and barriers to recruitment to the magnetic trial
Kaur, G., Smyth, R., Powell, C., & Williamson, P. (2013). A survey of facilitators and barriers to recruitment to the magnetic trial. Trials, 14(Suppl 1), O60. doi:10.1186/1745-6215-14-s1-o60
Adherence and variability in warfarin dose requirements: assessment in a prospective cohort
Jorgensen, A., Hughes, D. A., Hanson, A., van Eker, D., Toh, C. H., Pirmohamed, M., & Williamson, P. R. (2013). Adherence and variability in warfarin dose requirements: assessment in a prospective cohort. Pharmacogenomics, 14(2). doi:10.2217/pgs
Adherence and variability in warfarin dose requirements: assessment in a prospective cohort
Jorgensen, A. L., Hughes, D. A., Hanson, A., van Eker, D., Toh, C. H., Pirmohamed, M., & Williamson, P. R. (2013). Adherence and variability in warfarin dose requirements: assessment in a prospective cohort. PHARMACOGENOMICS, 14(2), 151-163. doi:10.2217/PGS.12.199
Adjusting for informative missing outcome data in clinical trials with longitudinal study designs
Kolamunnage-Dona, R., Powel, C., & Williamson, P. (2013). Adjusting for informative missing outcome data in clinical trials with longitudinal study designs. Trials, 14(Suppl 1), P109. doi:10.1186/1745-6215-14-s1-p109
Adjusting for treatment changes in epilepsy: causal analysis of randomised controlled trial survival outcomes in the presence of departure from randomised treatment
Dodd, S., Williamson, P., Dona, R. K., Van der Hoek, M., & White, I. (2013). Adjusting for treatment changes in epilepsy: causal analysis of randomised controlled trial survival outcomes in the presence of departure from randomised treatment. Trials, 14(Suppl 1), O37. doi:10.1186/1745-6215-14-s1-o37
Authors' response
Field, J. K., Baldwin, D., Brain, K., Devaraj, A., Eisen, T., Duffy, S. W., . . . Williamson, P. (2013). Authors' response. THORAX, 68(1), 105. doi:10.1136/thoraxjnl-2012-202442
Clinical trials in rare diseases: a review of practice
Bell, S., Williamson, P., Day, S., Wheatley, K., Whitehead, J., & Smith, C. T. (2013). Clinical trials in rare diseases: a review of practice. Trials, 14(Suppl 1), P34. doi:10.1186/1745-6215-14-s1-p34
Collating the knowledge base for the COMET (core outcome measures in effectiveness trials) initiative - a systematic review
Gargon, E., Gurung, B., & Williamson, P. (2013). Collating the knowledge base for the COMET (core outcome measures in effectiveness trials) initiative - a systematic review. Trials, 14(Suppl 1), O67. doi:10.1186/1745-6215-14-s1-o67
Core outcome set development: the effect of Delphi panel composition and feedback on prioritisation of outcomes
Macefield, R., Blencowe, N., Brookes, S., Jacobs, M., Sprangers, M., Williamson, P., & Blazeby, J. (2013). Core outcome set development: the effect of Delphi panel composition and feedback on prioritisation of outcomes. Trials, 14(Suppl 1), P77. doi:10.1186/1745-6215-14-s1-p77
Design considerations in the development of a core outcome set
Harman, N., Bruce, I., Callery, P., Tierney, S., O'Brien, K., & Williamson, P. (2013). Design considerations in the development of a core outcome set. Trials, 14(Suppl 1), O68. doi:10.1186/1745-6215-14-s1-o68
Guidance to detect, evaluate and prevent the problem of selective reporting in trial publications
Dwan, K., Williamson, P. R., Gamble, C., Higgins, J., Sterne, J., Altman, D. G., . . . Kirkham, J. J. (2013). Guidance to detect, evaluate and prevent the problem of selective reporting in trial publications. Trials, 14(Suppl 1), O91. doi:10.1186/1745-6215-14-s1-o91
Has the rheumatoid arthritis (RA) core outcome set influenced the selection of study outcome measures?
Kirkham, J., Boers, M., Tugwell, P., Clarke, M., & Williamson, P. (2013). Has the rheumatoid arthritis (RA) core outcome set influenced the selection of study outcome measures?. Trials, 14(Suppl 1), O66. doi:10.1186/1745-6215-14-s1-o66
MAGNEsium Trial In Children (MAGNETIC): a randomised, placebo-controlled trial and economic evaluation of nebulised magnesium sulphate in acute severe asthma in children.
Powell, C. V. E., Kolamunnage-Dona, R., Lowe, J., Boland, A., Petrou, S., Doull, I., . . . MAGNETIC study group. (2013). MAGNEsium Trial In Children (MAGNETIC): a randomised, placebo-controlled trial and economic evaluation of nebulised magnesium sulphate in acute severe asthma in children.. Health technology assessment (Winchester, England), 17(45), v-216. doi:10.3310/hta17450
Management of Asthma in School age Children On Therapy (MASCOT): a randomised, double-blind, placebo-controlled, parallel study of efficacy and safety
Lenney, W., McKay, A. J., Tudur Smith, C., Williamson, P. R., James, M., & Price, D. (2013). Management of Asthma in School age Children On Therapy (MASCOT): a randomised, double-blind, placebo-controlled, parallel study of efficacy and safety. HTA, 17(4), 1-218.
New European Union regulation of clinical trials is conflicting on deferred consent in emergency situations
Gamble, C., Woolfall, K., Williamson, P. R., Appleton, R., & Young, B. (2013). New European Union regulation of clinical trials is conflicting on deferred consent in emergency situations. BMJ, 346.
Opening research sites in multicentre clinical trials within the UK: a detailed analysis of delays
Williamson, P., Gamble, C., Kearney, A., & Hickey, H. (2013). Opening research sites in multicentre clinical trials within the UK: a detailed analysis of delays. Trials, 14(Suppl 1), O59. doi:10.1186/1745-6215-14-s1-o59
Optimising the design and evaluation of pilot work to inform the main trial: a review of current evidence and consideration of future practices
O'Connell Francischetto, E., Avery, K., Metcalfe, C., Williamson, P., Gamble, C., & Blazeby, J. (2013). Optimising the design and evaluation of pilot work to inform the main trial: a review of current evidence and consideration of future practices. Trials, 14(Suppl 1), O17.
Parents’ Agendas in Paediatric Clinical Trial Recruitment Are Different from Researchers’ and Often Remain Unvoiced: A Qualitative Study
Woolfall, K., Shilling, V., Hickey, H., Smyth, R. L., Sowden, E., Williamson, P. R., & Young, B. (n.d.). Parents’ Agendas in Paediatric Clinical Trial Recruitment Are Different from Researchers’ and Often Remain Unvoiced: A Qualitative Study. PLoS ONE, 8(7), e67352. doi:10.1371/journal.pone.0067352
Pregnancy outcomes in AMIPROM: a pilot RCT on serial transabdominal amnioinfusion versus expectant management in very early preterm perlabour rupture of membranes
Roberts, D., Vause, S., Martin, W., Green, P., Walkinshaw, S., Bricker, L., . . . Alfirevic, Z. (2013). Pregnancy outcomes in AMIPROM: a pilot RCT on serial transabdominal amnioinfusion versus expectant management in very early preterm perlabour rupture of membranes. BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY, 120, 10-11. Retrieved from https://www.webofscience.com/
Sample size formula for joint modelling of longitudinal and time-to-event data in clinical trials
Powney, M., Williamson, P., & Kolamunnage-Dona, R. (2013). Sample size formula for joint modelling of longitudinal and time-to-event data in clinical trials. Trials, 14(Suppl 1), O108. doi:10.1186/1745-6215-14-s1-o108
Systematic Review of the Selective Reporting of Analyses
Dwan, K., Gamble, C., Williamson, P. R., Higgins, J. P. T., Sterne, J. A. C., Altman, D. G., . . . Kirkham, J. J. (2013). Systematic Review of the Selective Reporting of Analyses. In The Cochrane Colloquium (pp. 1). Quebec City: Wiley-Blackwell.
Systematic Review of the Selective Reporting of Analyses
Dwan, K., Gable, C., Williamson, P. R., Higgins, J. P., Sterne, J. A., Altman, D. G., . . . Kirkham, J. J. (2013). Systematic Review of the Selective Reporting of Analyses. In Peer Review Congress (pp. 1). Chicago: BMJ.
The comet initiative
Williamson, P. (2013). The comet initiative. Trials, 14(Suppl 1), O65. doi:10.1186/1745-6215-14-s1-o65
The uniqueness of the United Kingdom Lung Cancer Screening trial (UKLS) - a population screening study
McRonald, F., Baldwin, D. R., Devaraj, A., Brain, K., Eisen, T., Holeman, J., . . . Field, J. K. (2013). The uniqueness of the United Kingdom Lung Cancer Screening trial (UKLS) - a population screening study. LUNG CANCER, 79, S28-S29. doi:10.1016/S0169-5002(13)70081-3
The use of systematic reviews in the planning, design and conduct of randomised trials: A retrospective cohort of NIHR HTA funded trials
Jones, A. P., Conroy, E., Williamson, P. R., Clarke, M., & Gamble, C. (2013). The use of systematic reviews in the planning, design and conduct of randomised trials: A retrospective cohort of NIHR HTA funded trials. BMC Medical Research Methodology, 13(50). Retrieved from http://www.biomedcentral.com/1471-2288/13/50
The use of systematic reviews in the planning, design and conduct of randomised trials: a retrospective cohort of NIHR HTA funded trials
Jones, A., Conroy, E., Williamson, P., Clarke, M., & Gamble, C. (2013). The use of systematic reviews in the planning, design and conduct of randomised trials: a retrospective cohort of NIHR HTA funded trials. In Trials Vol. 14 (pp. O92). doi:10.1186/1745-6215-14-s1-o92
What are parents’ priorities when being invited to enter their child into a clinical trial and how far do they voice their priorities?
Young, B., Woolfall, K., & Williamson, P. (2013). What are parents’ priorities when being invited to enter their child into a clinical trial and how far do they voice their priorities?. Trials, 14(Suppl 1), O72. doi:10.1186/1745-6215-14-s1-o72
2012
Assessing the consistency assumption by exploring treatment by covariate interactions in mixed treatment comparison meta-analysis: individual patient-level covariates versus aggregate trial-level covariates
Donegan, S., Williamson, P., D'Alessandro, U., & Smith, C. T. (2012). Assessing the consistency assumption by exploring treatment by covariate interactions in mixed treatment comparison meta-analysis: individual patient-level covariates versus aggregate trial-level covariates. STATISTICS IN MEDICINE, 31(29), 3840-3857. doi:10.1002/sim.5470
Adverse Drug Reactions Causing Admission to a Paediatric Hospital
Gallagher, R. M., Mason, J. R., Bird, K. A., Kirkham, J. J., Peak, M., Williamson, P. R., . . . Smyth, R. L. (2012). Adverse Drug Reactions Causing Admission to a Paediatric Hospital. PLOS ONE, 7(12). doi:10.1371/journal.pone.0050127
Nonadherence to treatment protocol in published randomised controlled trials: a review
Dodd, S., White, I. R., & Williamson, P. (2012). Nonadherence to treatment protocol in published randomised controlled trials: a review. Trials, 13(1). doi:10.1186/1745-6215-13-84
Developing a survey of barriers and facilitators to recruitment in randomized controlled trials
Kaur, G., Smyth, R. L., & Williamson, P. (2012). Developing a survey of barriers and facilitators to recruitment in randomized controlled trials. TRIALS, 13. doi:10.1186/1745-6215-13-218
Melatonin for sleep problems in children with neurodevelopmental disorders: randomised double masked placebo controlled trial
Gringras, P., Gamble, C., Jones, A. P., Wiggs, L., Williamson, P. R., Sutcliffe, A., . . . Appleton, R. (2012). Melatonin for sleep problems in children with neurodevelopmental disorders: randomised double masked placebo controlled trial. BMJ, 345(nov05 1), e6664. doi:10.1136/bmj.e6664
Melatonin for sleep problems in children with neurodevelopmental disorders: randomised double masked placebo controlled trial
Gringras, P., Gamble, C., Jones, A. P., Wiggs, L., Williamson, P. R., Sutcliffe, A., . . . Appleton, R. (2012). Melatonin for sleep problems in children with neurodevelopmental disorders: randomised double masked placebo controlled trial. BRITISH MEDICAL JOURNAL, 345. doi:10.1136/bmj.e6664
The use of MElatonin in children with Neurodevelopmental Disorders and impaired Sleep: a randomised, double-blind, placebo-controlled, parallel study (MENDS)
Appleton, R. E., Jones, A. P., Gamble, C., Williamson, P. R., Wiggs, L., Montgomery, P., . . . Gringras, P. (2012). The use of MElatonin in children with Neurodevelopmental Disorders and impaired Sleep: a randomised, double-blind, placebo-controlled, parallel study (MENDS). HEALTH TECHNOLOGY ASSESSMENT, 16(40), 1-+. doi:10.3310/hta16400
A multivariate meta-analysis approach for reducing the impact of outcome reporting bias in systematic reviews
Kirkham, J. J., Riley, R. D., & Williamson, P. R. (2012). A multivariate meta-analysis approach for reducing the impact of outcome reporting bias in systematic reviews. STATISTICS IN MEDICINE, 31(20), 2179-2195. doi:10.1002/sim.5356
Influence of CYP2C9 and VKORC1 on Patient Response to Warfarin: A Systematic Review and Meta-Analysis
Jorgensen, A. L., FitzGerald, R. J., Oyee, J., Pirmohamed, M., & Williamson, P. R. (2012). Influence of CYP2C9 and VKORC1 on Patient Response to Warfarin: A Systematic Review and Meta-Analysis. PLOS ONE, 7(8). doi:10.1371/journal.pone.0044064
Developing core outcome sets for clinical trials: issues to consider
Williamson, P. R., Altman, D. G., Blazeby, J. M., Clarke, M., Devane, D., Gargon, E., & Tugwell, P. (2012). Developing core outcome sets for clinical trials: issues to consider. TRIALS, 13. doi:10.1186/1745-6215-13-132
Development of a core outcome set for clinical trials in childhood asthma: a survey of clinicians, parents, and young people
Sinha, I. P., Gallagher, R., Williamson, P. R., & Smyth, R. L. (2012). Development of a core outcome set for clinical trials in childhood asthma: a survey of clinicians, parents, and young people. TRIALS, 13. doi:10.1186/1745-6215-13-103
Nonadherence to treatment protocol in published randomised controlled trials: a review
Dodd, S., White, I. R., & Williamson, P. (2012). Nonadherence to treatment protocol in published randomised controlled trials: a review. TRIALS, 13. doi:10.1186/1745-6215-13-84
Standard 5: Selection, Measurement, and Reporting of Outcomes in Clinical Trials in Children
Sinha, I. P., Altman, D. G., Beresford, M. W., Boers, M., Clarke, M., Craig, J., . . . Smyth, R. L. (2012). Standard 5: Selection, Measurement, and Reporting of Outcomes in Clinical Trials in Children. PEDIATRICS, 129, S146-S152. doi:10.1542/peds.2012-0055H
Repeated Origin and Loss of Adhesive Toepads in Geckos
Gamble, T., Greenbaum, E., Jackman, T. R., Russell, A. P., & Bauer, A. M. (2012). Repeated Origin and Loss of Adhesive Toepads in Geckos. PLOS ONE, 7(6). doi:10.1371/journal.pone.0039429
THE COMET (CORE OUTCOME MEASURES IN EFFECTIVENESS TRIALS) INITIATIVE: ITS ROLE IN IMPROVING COCHRANE REVIEWS
Williamson, P., & Clarke, M. (2012). THE COMET (CORE OUTCOME MEASURES IN EFFECTIVENESS TRIALS) INITIATIVE: ITS ROLE IN IMPROVING COCHRANE REVIEWS. COCHRANE DATABASE OF SYSTEMATIC REVIEWS, (4). doi:10.1002/14651858.ED000041
Prognostic factors for time to treatment failure and time to 12 months of remission for patients with focal epilepsy: post-hoc, subgroup analyses of data from the SANAD trial
Bonnett, L., Smith, C. T., Smith, D., Williamson, P., Chadwick, D., & Marson, A. G. (2012). Prognostic factors for time to treatment failure and time to 12 months of remission for patients with focal epilepsy: post-hoc, subgroup analyses of data from the SANAD trial. LANCET NEUROLOGY, 11(4), 331-340. doi:10.1016/S1474-4422(12)70018-2
Adverse Drug Reactions in Children-A Systematic Review
Smyth, R. M. D., Gargon, E., Kirkham, J., Cresswell, L., Golder, S., Smyth, R., & Williamson, P. (2012). Adverse Drug Reactions in Children-A Systematic Review. PLOS ONE, 7(3). doi:10.1371/journal.pone.0024061
A randomised, double masked, placebo controlled trial of melatonin for sleep problems in children with Neurodevelopmental Disorders
Gringras, P., Gamble, C., Jones, A. P., Wiggs, L., Williamson, P. R., Sutcliffe, A., . . . Appleton, R. (2012). A randomised, double masked, placebo controlled trial of melatonin for sleep problems in children with Neurodevelopmental Disorders. BMJ, 345.
Combining individual patient data and aggregate data in mixed treatment comparison meta-analysis: individual patient data may be beneficial if only for a subset of trials
Donegan, S., Williamson, P. R., D'Alessandro, U., Garner, P., & Tudur Smith, C. (2012). Combining individual patient data and aggregate data in mixed treatment comparison meta-analysis: individual patient data may be beneficial if only for a subset of trials. Statistics in Medicine.
Core outcome sets and the COMET (core outcome measures in effectiveness trials) initiative; improving the efficiency and value of the research process
Blazeby, J., Altman, D. G., Clarke, M., Gargon, E. A., & Williamson, P. R. (2012). Core outcome sets and the COMET (core outcome measures in effectiveness trials) initiative; improving the efficiency and value of the research process. QUALITY OF LIFE RESEARCH, 21, 19-20. Retrieved from https://www.webofscience.com/
Development and inter-rater reliability of the Liverpool ADR causality assessment tool
Gallagher, R. M., Kirkham, J. J., Mason, J. R., Bird, K. A., Williamson, P. R., Nunn, A. J., . . . Pirmohamed, M. (2012). Development and inter-rater reliability of the Liverpool ADR causality assessment tool. PLoS One.
Driving up the quality and relevance of research through the use of agreed core outcomes
Williamson, P., Altman, D., Blazeby, J., Clarke, M., & Gargon, E. (2012). Driving up the quality and relevance of research through the use of agreed core outcomes. JOURNAL OF HEALTH SERVICES RESEARCH & POLICY, 17(1), 1-2. doi:10.1258/jhsrp.2011.011131
External Validation of Prognostic Models
Bonnett, L. J., Marson, A. G., Williamson, P. R., & Tudur Smith, C. (2012). External Validation of Prognostic Models. In Survival Analysis for Junior Researchers (pp. 17). Leicester: University of Leicester.
External validation of a prognostic model in epilepsy: simulation study and case study
Bonnett, L. J., Marson, A. G., Williamson, P. R., & Tudur Smith, C. (2012). External validation of a prognostic model in epilepsy: simulation study and case study. In 33rd Annual Conference of the International Society for Clinical Biostatistics (pp. 113). Bergen: ISCB.
MAGNESIUM TRIAL IN CHILDREN (MAGNETIC): A Randomised, Placebo Controlled Trial of Nebulised Magnesium Sulphate in Acute Severe Asthma in Children
Powell, C. V. E., Kolamunnage-Dona, R., Lowe, J., Boland, A., Petrou, S., Doull, I., . . . on behalf of the MAGNETIC study group. (2012). MAGNESIUM TRIAL IN CHILDREN (MAGNETIC): A Randomised, Placebo Controlled Trial of Nebulised Magnesium Sulphate in Acute Severe Asthma in Children. Health Technology Assessment.
PROGNOSTIC FACTORS FOR TIME TO TREATMENT FAILURE AND TIME TO 12 MONTH REMISSION FOR PATIENTS WITH GENERALISED EPILEPSY: POST HOC AND SUBGROUP ANALYSES OF SANAD
Bonnett, L. J., Smith, C. T., Smith, D., Williamson, P., Chadwick, D., & Marson, A. (2012). PROGNOSTIC FACTORS FOR TIME TO TREATMENT FAILURE AND TIME TO 12 MONTH REMISSION FOR PATIENTS WITH GENERALISED EPILEPSY: POST HOC AND SUBGROUP ANALYSES OF SANAD. In EPILEPSIA Vol. 53 (pp. 77). Retrieved from https://www.webofscience.com/
Prognostic factors for time to treatment failure and time to 12 month remission for patients with generalised epilepsy: post-hoc and subgroup analyses of SANAD
Bonnett, L. J., Tudur Smith, C., Smith, D., Williamson, P. R., Chadwick, D., & Marson, A. G. (2012). Prognostic factors for time to treatment failure and time to 12 month remission for patients with generalised epilepsy: post-hoc and subgroup analyses of SANAD. In 10th European Congress on Epileptology (pp. 104). London: ILAE.
Repeated origin and loss of adhesive toepads in geckos.
Gamble, T., Greenbaum, E., Jackman, T. R., Russell, A. P., & Bauer, A. M. (2012). Repeated origin and loss of adhesive toepads in geckos.. PloS one, 7(6), e39429. doi:10.1371/journal.pone.0039429
Tuberculosis through the rose tinted spectacles of the EBUS endoscopist: be aware of the bias response
Field, J., Baldwin, D., Brain, K., Devaraj, A., Eisen, T., Duffy, S. W., . . . Williamson, P. (2012). Tuberculosis through the rose tinted spectacles of the EBUS endoscopist: be aware of the bias response. THORAX, 67(7), 650. doi:10.1136/thoraxjnl-2011-200822
What Parents of Children Who Have Received Emergency Care Think about Deferring Consent in Randomised Trials of Emergency Treatments: Postal Survey
Gamble, C., Nadel, S., Snape, D., McKay, A., Hickey, H., Williamson, P., . . . Young, B. (n.d.). What Parents of Children Who Have Received Emergency Care Think about Deferring Consent in Randomised Trials of Emergency Treatments: Postal Survey. PLoS ONE, 7(5), e35982. doi:10.1371/journal.pone.0035982
joineR: Joint modelling of repeated measurements and time-to-event data.
Philipson, P., Sousa, I., Diggle, P., Williamson, P., Kolamunnage-Dona, R., & Henderson, R. (2012). joineR: Joint modelling of repeated measurements and time-to-event data. (Version 1) [Internet (free access)]. Comprehensive R Archive Network, United Kingdom.. Retrieved from http://cran.r-project.org/web/packages/joineR/index.html
2011
Development and Inter-Rater Reliability of the Liverpool Adverse Drug Reaction Causality Assessment Tool
Gallagher, R. M., Kirkham, J. J., Mason, J. R., Bird, K. A., Williamson, P. R., Nunn, A. J., . . . Pirmohamed, M. (2011). Development and Inter-Rater Reliability of the Liverpool Adverse Drug Reaction Causality Assessment Tool. PLOS ONE, 6(12). doi:10.1371/journal.pone.0028096
Seizure recurrence after antiepileptic drug withdrawal and the implications for driving: further results from the MRC Antiepileptic Drug Withdrawal Study and a systematic review
Bonnett, L. J., Shukralla, A., Tudur-Smith, C., Williamson, P. R., & Marson, A. G. (2011). Seizure recurrence after antiepileptic drug withdrawal and the implications for driving: further results from the MRC Antiepileptic Drug Withdrawal Study and a systematic review. JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, 82(12), 1328-1333. doi:10.1136/jnnp.2010.222885
A Head-to-Head Comparison of Four Artemisinin-Based Combinations for Treating Uncomplicated Malaria in African Children: A Randomized Trial
Atwine, D., Balikagala, B., Bassat, Q., Chalwe, V., D'Alessandro, U., Dhorda, M., . . . Yeka, A. (2011). A Head-to-Head Comparison of Four Artemisinin-Based Combinations for Treating Uncomplicated Malaria in African Children: A Randomized Trial. PLOS MEDICINE, 8(11). doi:10.1371/journal.pmed.1001119
Reporting of adverse events in randomised controlled trials of antiepileptic drugs using the CONSORT criteria for reporting harms
Shukralla, A. A., Tudur-Smith, C., Powell, G. A., Williamson, P. R., & Marson, A. G. (2011). Reporting of adverse events in randomised controlled trials of antiepileptic drugs using the CONSORT criteria for reporting harms. EPILEPSY RESEARCH, 97(1-2), 20-29. doi:10.1016/j.eplepsyres.2011.06.015
CT screening for lung cancer in the UK: position statement by UKLS investigators following the NLST report
Field, J. K., Baldwin, D., Brain, K., Devaraj, A., Eisen, T., Duffy, S. W., . . . Whynes, D. (2011). CT screening for lung cancer in the UK: position statement by UKLS investigators following the NLST report. THORAX, 66(8), 736-737. doi:10.1136/thoraxjnl-2011-200351
Communication about Children's Clinical Trials as Observed and Experienced: Qualitative Study of Parents and Practitioners
Shilling, V., Williamson, P. R., Hickey, H., Sowden, E., Beresford, M. W., Smyth, R. L., & Young, B. (2011). Communication about Children's Clinical Trials as Observed and Experienced: Qualitative Study of Parents and Practitioners. PLOS ONE, 6(7). doi:10.1371/journal.pone.0021604
A randomised controlled trial of extended brief intervention for alcohol dependent patients in an acute hospital setting (ADPAC)
Owens, L., Butcher, G., Gilmore, I., Kolamunnage-Dona, R., Oyee, J., Perkins, L., . . . Pirmohamed, M. (2011). A randomised controlled trial of extended brief intervention for alcohol dependent patients in an acute hospital setting (ADPAC). BMC PUBLIC HEALTH, 11. doi:10.1186/1471-2458-11-528
Processes in recruitment to randomised controlled trials of medicines for children (RECRUIT): a qualitative study
Shilling, V., Williamson, P. R., Hickey, H., Sowden, E., Smyth, R. L., & Young, B. (2011). Processes in recruitment to randomised controlled trials of medicines for children (RECRUIT): a qualitative study. HEALTH TECHNOLOGY ASSESSMENT, 15(15), 1-+. doi:10.3310/hta15150
Adverse drug reactions causing admission to a paediatric hospital: a pilot study
Gallagher, R. M., Bird, K. A., Mason, J. R., Peak, M., Williamson, P. R., Nunn, A. J., . . . Smyth, R. L. (2011). Adverse drug reactions causing admission to a paediatric hospital: a pilot study. JOURNAL OF CLINICAL PHARMACY AND THERAPEUTICS, 36(2), 194-199. doi:10.1111/j.1365-2710.2010.01194.x
Adverse drug reactions causing admission to a paediatric hospital: a pilot study
Gallagher, R. M., Bird, K. A., Mason, J. R., Peak, M., Williamson, P. R., Nunn, A. J., . . . Smyth, R. L. (2011). Adverse drug reactions causing admission to a paediatric hospital: a pilot study. Journal of Clinical Pharmacy and Therapeutics, 36(2), 194-199. doi:10.1111/j.1365-2710.2010.01194.x
Using the Delphi Technique to Determine Which Outcomes to Measure in Clinical Trials: Recommendations for the Future Based on a Systematic Review of Existing Studies
Sinha, I. P., Smyth, R. L., & Williamson, P. R. (2011). Using the Delphi Technique to Determine Which Outcomes to Measure in Clinical Trials: Recommendations for the Future Based on a Systematic Review of Existing Studies. PLOS MEDICINE, 8(1). doi:10.1371/journal.pmed.1000393
Comparison of protocols and registry entries to published reports for randomised controlled trials
Dwan, K., Altman, D. G., Cresswell, L., Blundell, M., Gamble, C. L., & Williamson, P. R. (2011). Comparison of protocols and registry entries to published reports for randomised controlled trials. COCHRANE DATABASE OF SYSTEMATIC REVIEWS, (1). doi:10.1002/14651858.MR000031.pub2
Frequency and reasons for outcome reporting bias in clinical trials: interviews with trialists
Smyth, R. M. D., Kirkham, J. J., Jacoby, A., Altman, D. G., Gamble, C., & Williamson, P. R. (2011). Frequency and reasons for outcome reporting bias in clinical trials: interviews with trialists. BMJ-BRITISH MEDICAL JOURNAL, 342. doi:10.1136/bmj.c7153
Anti-epileptic drug harms: issues for meta-analysis
Smith, C. T., Shukralla, A., Donegan, S., Hemming, K., Powell, G. A., Williamson, P., & Marson, A. (2011). Anti-epileptic drug harms: issues for meta-analysis. In Trials Vol. 12 (pp. A11). doi:10.1186/1745-6215-12-s1-a11
CT screening for lung cancer in the UK: position statement by UKLS investigators following the NLST report
Field, J. K., Baldwin, D., Brain, K., Devaraj, A., Eisen, T., Duffy, S. W., . . . Whynes, D. (2011). CT screening for lung cancer in the UK: position statement by UKLS investigators following the NLST report. Thorax, 66(8), 736-737.
Communication about Children's Clinical Trials as Observed and Experienced: Qualitative Study of Parents and Practitioners
Shilling, V., Williamson, P. R., Hickey, H., Sowden, E., & Beresford, M. W. (2011). Communication about Children's Clinical Trials as Observed and Experienced: Qualitative Study of Parents and Practitioners. PLoS One.
Departure from treatment protocol in published randomised controlled trials: a review
Dodd, S., White, I., & Williamson, P. (2011). Departure from treatment protocol in published randomised controlled trials: a review. Trials, 12(Suppl 1), A129. doi:10.1186/1745-6215-12-s1-a129
Factors influencing the risk of seizure recurrence in patients with epilepsy and the implications for driving
Bonnett, L. J., Shukralla, A., Tudur Smith, C., Williamson, P. R., & Marson, A. G. (2011). Factors influencing the risk of seizure recurrence in patients with epilepsy and the implications for driving. In Royal Statistical Society Merseyside Local Group Meeting (pp. n/a). Liverpool: RSS Merseyside. Retrieved from http://sites.google.com/
Feasibility of establishing a central repository for the individual participant data from research studies
Smith, C. T., Dwan, K., Clarke, M., Riley, R., Altman, D., & Williamson, P. (2011). Feasibility of establishing a central repository for the individual participant data from research studies. Trials, 12(Suppl 1), A56. doi:10.1186/1745-6215-12-s1-a56
Handling Variables with Every Entry Missing in the Context of External Validation of a Prognostic Model
Bonnett, L. J., Marson, A. G., Williamson, P. R., & Tudur Smith, C. (2011). Handling Variables with Every Entry Missing in the Context of External Validation of a Prognostic Model. In All Models are wrong... (pp. n/a). Groningen: University of Groningen. Retrieved from http://www.math.rug.nl/stat/models/poster_abstracts.html
Individual participant data meta-analyses compared with meta-analyses based on aggregate data
Smith, C. T., Oyee, J., Marcucci, M., Rovers, M., Iorio, A., Riley, R., . . . Clarke, M. (2011). Individual participant data meta-analyses compared with meta-analyses based on aggregate data. Trials, 12(Suppl 1), A57. doi:10.1186/1745-6215-12-s1-a57
Simulation study - Handling missing covariates in the context of external validation
Bonnett, L. J., Marson, A. G., Williamson, P. R., & Tudur Smith, C. (2011). Simulation study - Handling missing covariates in the context of external validation. In MRC Clinical Trials Methodology Conference (pp. 23). Bristol: MRC Hubs for Trials Methodology Research.
Simulation study - handling missing covariates in the context of external validation
Bonnett, L. J., Marson, T. G., Williamson, P. R., & Tudur-Smith, C. (2011). Simulation study - handling missing covariates in the context of external validation. In Trials Vol. 12 (pp. A62). doi:10.1186/1745-6215-12-s1-a62
The COMET (Core Outcome Measures in Effectiveness Trials) Initiative
Williamson, P. R., Altman, D. G., Blazeby, J. M., Clarke, M., & Gargon, E. (2011). The COMET (Core Outcome Measures in Effectiveness Trials) Initiative. Trials, 12(Suppl 1), A70. doi:10.1186/1745-6215-12-s1-a70
The use of Systematic reviews in the design of randomised controlled trials
Jones, A. P., Williamson, P. R., Clarke, M., & Gamble, C. (2011). The use of Systematic reviews in the design of randomised controlled trials. In MRC North West Hub for Trials Methodology Research 'Showcase Meeting' Vol. -. Liverpool: -.
The use of Systematic reviews in the design of randomised controlled trials
Jones, A. P., Williamson, P. R., Clarke, M., & Gamble, C. (2011). The use of Systematic reviews in the design of randomised controlled trials. In Clinical Trials Methodology conference Vol. -. -: MRC Network of HUBS for trials methodology Research.
The use of systematic reviews in the design of randomised trials
Jones, A. P., Gamble, C., Clarke, M., & Williamson, P. R. (2011). The use of systematic reviews in the design of randomised trials [Undetermined].
UNITED KINGDOM LUNG CANCER SCREENING (UKLS) TRIAL
Field, J. K., Duffy, S., Baldwin, D., Brain, K., Eisen, T., Hands, C. J. D., . . . Hansell, D. (2011). UNITED KINGDOM LUNG CANCER SCREENING (UKLS) TRIAL. JOURNAL OF THORACIC ONCOLOGY, 6(6), S1382-S1383. Retrieved from https://www.webofscience.com/
What parents think about being approached about children’s trials, how this differs from what practitioners expect, and what this tells us about enhancing recruitment
Young, B., Shilling, V., Hickey, H., Sowden, E., Smyth, R. L., & Williamson, P. R. (2011). What parents think about being approached about children’s trials, how this differs from what practitioners expect, and what this tells us about enhancing recruitment. Trials, 12(Suppl 1), A116. doi:10.1186/1745-6215-12-s1-a116
2010
Risk of recurrence after a first seizure and implications for driving: further analysis of the Multicentre study of early Epilepsy and Single Seizures
Bonnett, L. J., Tudur-Smith, C., Williamson, P. R., & Marson, A. G. (2010). Risk of recurrence after a first seizure and implications for driving: further analysis of the Multicentre study of early Epilepsy and Single Seizures. BRITISH MEDICAL JOURNAL, 341. doi:10.1136/bmj.c6477
Bias Due to Changes in Specified Outcomes during the Systematic Review Process
Kirkham, J. J., Altman, D. G., & Williamson, P. R. (2010). Bias Due to Changes in Specified Outcomes during the Systematic Review Process. In PLOS ONE Vol. 5. doi:10.1371/journal.pone.0009810
Indirect Comparisons: A Review of Reporting and Methodological Quality
Donegan, S., Williamson, P., Gamble, C., & Tudur-Smith, C. (2010). Indirect Comparisons: A Review of Reporting and Methodological Quality. PLOS ONE, 5(11). doi:10.1371/journal.pone.0011054
Assessing the potential for outcome reporting bias in a review: a tutorial
Dwan, K., Gamble, C., Kolamunnage-Dona, R., Mohammed, S., Powell, C., & Williamson, P. R. (2010). Assessing the potential for outcome reporting bias in a review: a tutorial. TRIALS, 11. doi:10.1186/1745-6215-11-52
Determining The Relevance Of Outcomes For Evaluating Regular Therapies For Children With Asthma – A Survey Of Clinicians, Parents And Young People
Sinha, I., Gallagher, R., Williamson, P. R., & Smyth, R. L. (2010). Determining The Relevance Of Outcomes For Evaluating Regular Therapies For Children With Asthma – A Survey Of Clinicians, Parents And Young People. In A55. CHILDHOOD ASTHMA EPIDEMIOLOGY (pp. A1870). American Thoracic Society. doi:10.1164/ajrccm-conference.2010.181.1_meetingabstracts.a1870
Communication about clinical trials as observed and experienced: the views of parents and practitioners
Shilling, V., Hickey, H., Smyth, R., Sowden, E., Williamson, P., & Young, B. (2010). Communication about clinical trials as observed and experienced: the views of parents and practitioners. Archives of Disease in Childhood, 95(Suppl 1), A1.1-A1. doi:10.1136/adc.2010.186338.1
Determining The Relevance Of Outcomes For Evaluating Regular Therapies For Children With Asthma-A Survey Of Clinicians, Parents And Young People
Sinha, I., Gallagher, R., Williamson, P. R., & Smyth, R. L. (2010). Determining The Relevance Of Outcomes For Evaluating Regular Therapies For Children With Asthma-A Survey Of Clinicians, Parents And Young People. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 181. Retrieved from https://www.webofscience.com/
Parent/carer views about deferred consent in trials of emergency treatments in children with life-threatening illness
Nadel, S., Young, B., Gamble, C., Hickey, H., Williamson, P., Snape, D., . . . Glennie, L. (2010). Parent/carer views about deferred consent in trials of emergency treatments in children with life-threatening illness. Archives of Disease in Childhood, 95(Suppl 1), A39.2-A39. doi:10.1136/adc.2010.186338.87
Bias due to changes in specified outcomes during the systematic review process.
Kirkham, J. J., Altman, D. G., & Williamson, P. R. (2010). Bias due to changes in specified outcomes during the systematic review process.. PloS one, 5(3), e9810. doi:10.1371/journal.pone.0009810
The impact of outcome reporting bias in randomised controlled trials on a cohort of systematic reviews
Kirkham, J. J., Dwan, K. M., Altman, D. G., Gamble, C., Dodd, S., Smyth, R., & Williamson, P. R. (2010). The impact of outcome reporting bias in randomised controlled trials on a cohort of systematic reviews. BMJ-BRITISH MEDICAL JOURNAL, 340. doi:10.1136/bmj.c365
Feasibility study to inform the design of a randomised controlled trial to eradicate <i>Pseudomonas aeruginosa</i> infection in individuals with Cystic Fibrosis
Hickey, H. R., Jones, A. P., Lenney, W., Williamson, P. R., & Smyth, R. L. (2010). Feasibility study to inform the design of a randomised controlled trial to eradicate <i>Pseudomonas aeruginosa</i> infection in individuals with Cystic Fibrosis. TRIALS, 11. doi:10.1186/1745-6215-11-11
Abstracts of the 2010 Joint Colloquium of The Cochrane and Campbell Collaborations
Abstracts of the 2010 Joint Colloquium of The Cochrane and Campbell Collaborations (n.d.). In Abstracts of the 2010 Joint Colloquium of The Cochrane and Campbell Collaborations. Wiley. doi:10.1002/14651858.cd000002
Comparison of protocols and registry entries to published reports for randomised controlled trials
Dwan, K., Altman, D. G., Blundell, M., Gamble, C. L., & Williamson, P. R. (n.d.). Comparison of protocols and registry entries to published reports for randomised controlled trials. In K. Dwan (Ed.). John Wiley & Sons, Ltd. doi:10.1002/14651858.mr000031
Comparison of protocols and registry entries to published reports for randomised controlled trials (Protocol)
Dwan, K., Altman, D. G., Blundell, M., Gamble, C. L., & Williamson, P. R. (2010). Comparison of protocols and registry entries to published reports for randomised controlled trials (Protocol). The Cochrane Library, (10).
Developing a Prognostic Model for Epilepsy Data
Bonnett, L. J., Tudur-Smith, C., Williamson, P. R., & Marson, A. G. (2010). Developing a Prognostic Model for Epilepsy Data. In 31st Annual Conference of the International Society for Clinical Biostatisticians (pp. 145). Montpellier: ISCB.
Evaluation of Longitudinal Biomarkers
Kolamunnage-Dona, R., Williamson, P., Toh, C. H., Welters, I., & Downey, C. (2010). Evaluation of Longitudinal Biomarkers. In METHODS FOR EVALUATING MEDICAL TESTS AND BIOMARKERS: 2010 Symposium (pp. 37). Birmingham: University of Birmingham.
Multilevel modelling of caries clinical trial data
Burnside, G., Pine, C., & Williamson, P. (2010). Multilevel modelling of caries clinical trial data. IADR July. Barcelona, Spain. J Dent Res, 89B, Abs 377.
Risk of Seizure Recurrence - Implications for Driving
Bonnett, L. J., Tudur-Smith, C., Williamson, P. R., & Marson, A. G. (2010). Risk of Seizure Recurrence - Implications for Driving. In Postgraduate Researchers in Science Medicine (pp. 15). Lancaster: Vitae.
2009
Phenytoin versus valproate monotherapy for partial onset seizures and generalized onset tonic-clonic seizures.
Tudur Smith, C., Marson, A. G., & Williamson, P. R. (2001). Phenytoin versus valproate monotherapy for partial onset seizures and generalized onset tonic-clonic seizures.. The Cochrane database of systematic reviews, (4), CD001769. doi:10.1002/14651858.cd001769
Effects of <i>CYP4F2</i> genetic polymorphisms and haplotypes on clinical outcomes in patients initiated on warfarin therapy
Zhang, J. E., Jorgensen, A. L., Alfirevic, A., Williamson, P. R., Toh, C. H., Park, B. K., & Pirmohamed, M. (2009). Effects of <i>CYP4F2</i> genetic polymorphisms and haplotypes on clinical outcomes in patients initiated on warfarin therapy. PHARMACOGENETICS AND GENOMICS, 19(10), 781-789. doi:10.1097/FPC.0b013e3283311347
Genetic and environmental factors determining clinical outcomes and cost of warfarin therapy: a prospective study
Jorgensen, A. L., Al-Zubiedi, S., Zhang, J. E., Keniry, A., Hanson, A., Hughes, D. A., . . . Pirmohamed, M. (2009). Genetic and environmental factors determining clinical outcomes and cost of warfarin therapy: a prospective study. PHARMACOGENETICS AND GENOMICS, 19(10), 800-812. doi:10.1097/FPC.0b013e3283317ab5
Rituximab for the treatment of rheumatoid arthritis
Bagust, A., Boland, A., Hockenhull, J., Fleeman, N., Greenhalgh, J., Dundar, Y., . . . Dickson, R. (n.d.). Rituximab for the treatment of rheumatoid arthritis. Health Technology Assessment, 13(Suppl 2), 23-29. doi:10.3310/hta13suppl2-04
Outcomes in Clinical Trials of Inhaled Corticosteroids for Children with Asthma Are Narrowly Focussed on Short Term Disease Activity
Sinha, I. P., Williamson, P. R., & Smyth, R. L. (2009). Outcomes in Clinical Trials of Inhaled Corticosteroids for Children with Asthma Are Narrowly Focussed on Short Term Disease Activity. PLOS ONE, 4(7). doi:10.1371/journal.pone.0006276
Erratum
Erratum (2009). Clinical Trials, 6(3), 288. doi:10.1177/1740774509339555
Interpreting regulatory trials in epilepsy
Marson, A. G., & Williamson, P. R. (2009). Interpreting regulatory trials in epilepsy. CURRENT OPINION IN NEUROLOGY, 22(2), 167-173. doi:10.1097/WCO.0b013e3283292427
Outcomes in Clinical Trials of Inhaled Corticosteroids for Children with Asthma Are Narrowly Focussed on Short Term Disease Activity.
Sinha, I. P., Williamson, P. R., & Smyth, R. L. (2009). Outcomes in Clinical Trials of Inhaled Corticosteroids for Children with Asthma Are Narrowly Focussed on Short Term Disease Activity.. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 179. Retrieved from https://www.webofscience.com/
Estimation of the Warfarin Dose with Clinical and Pharmacogenetic Data
Klein, T. E., Altman, R. B., Eriksson, N., Gage, B. F., Kimmel, S. E., Lee, M. -T. M., . . . Shin, J. G. (2009). Estimation of the Warfarin Dose with Clinical and Pharmacogenetic Data. NEW ENGLAND JOURNAL OF MEDICINE, 360(8), 753-764. Retrieved from https://www.webofscience.com/
Adverse Drug Reactions in Hospital In-Patients: A Prospective Analysis of 3695 Patient-Episodes
Davies, E. C., Green, C. F., Taylor, S., Williamson, P. R., Mottram, D. R., & Pirmohamed, M. (2009). Adverse Drug Reactions in Hospital In-Patients: A Prospective Analysis of 3695 Patient-Episodes. PLOS ONE, 4(2). doi:10.1371/journal.pone.0004439
Meta-analysis of individual patient data versus aggregate data from longitudinal clinical trials
Jones, A. P., Riley, R. D., Williamson, P. R., & Whitehead, A. (2009). Meta-analysis of individual patient data versus aggregate data from longitudinal clinical trials. CLINICAL TRIALS, 6(1), 16-27. doi:10.1177/1740774508100984
OVERALL RESULTS OF SANAD ARE CONSISTENT ACROSS EPILEPSY SYNDROMES
Marson, A., Smith, D., Smith, C. T., Jacoby, A., Williamson, P., & Chadwick, D. (2009). OVERALL RESULTS OF SANAD ARE CONSISTENT ACROSS EPILEPSY SYNDROMES. In JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY Vol. 80 (pp. 108). Retrieved from https://www.webofscience.com/
Outcome reporting bias in trials (ORBIT)
Kirkham, J. J., Dwan, K., Altman, D., Gamble, C., Dodd, S., Jacoby, A., . . . Williamson, P. R. (2009). Outcome reporting bias in trials (ORBIT). In Cochrane Colloquium (pp. 12). Singapore: Wiley-Blackwell.
Oxcarbazepine versus phenytoin monotherapy for epilepsy
Muller, M., Marson, A. G., & Williamson, P. R. (2009). Oxcarbazepine versus phenytoin monotherapy for epilepsy. Cochrane Database of Systematic Reviews, (4). doi:10.1002/14651858.CD003615.pub2.
PROGNOSTIC FACTORS FOR 12-MONTH REMISSION
Bonnett, L., Tudur-Smith, C., Williamson, P., & Marson, T. (2009). PROGNOSTIC FACTORS FOR 12-MONTH REMISSION. In EPILEPSIA Vol. 50 (pp. 110). Retrieved from https://www.webofscience.com/
Rituximab for the treatment of rheumatoid arthritis
Bagust, A., Boland, A., Hockenhull, J., Fleeman, N., Greenhalgh, J., Dundar, Y., . . . Dickson, R. (2009). Rituximab for the treatment of rheumatoid arthritis. HEALTH TECHNOLOGY ASSESSMENT, 13, 23-29. doi:10.3310/hta13suppl2/04
2008
Joint modelling of longitudinal and competing risks data
Williamson, P. R., Kolamunnage-Dona, R., Philipson, R., & Marson, A. G. (2008). Joint modelling of longitudinal and competing risks data. STATISTICS IN MEDICINE, 27(30), 6426-6438. doi:10.1002/sim.3451
Methodological quality of pharmacogenetic studies: Issues of concern
Jorgensen, A. L., & Williamson, P. R. (2008). Methodological quality of pharmacogenetic studies: Issues of concern. STATISTICS IN MEDICINE, 27(30), 6547-6569. doi:10.1002/sim.3420
Meta-analysis of diagnostic test studies using individual patient data and aggregate data
Riley, R. D., Dodd, S. R., Craig, J. V., Thompson, J. R., & Williamson, P. R. (2008). Meta-analysis of diagnostic test studies using individual patient data and aggregate data. STATISTICS IN MEDICINE, 27(29), 6111-6136. doi:10.1002/sim.3441
Reporting of clinical trials: a review of research funders' guidelines
Dwan, K., Gamble, C., Williamson, P. R., & Altman, D. G. (2008). Reporting of clinical trials: a review of research funders' guidelines. TRIALS, 9. doi:10.1186/1745-6215-9-66
Cervical Stitch (Cerclage) For Preventing Pregnancy Loss: Individual Patient Data Meta-Analysis
Jorgensen, A. L., Alfirevic, Z., Tudur Smith, C., & Williamson, P. R. (2008). Cervical Stitch (Cerclage) For Preventing Pregnancy Loss: Individual Patient Data Meta-Analysis. Obstetric Anesthesia Digest, 28(3), 149-150. doi:10.1097/01.aoa.0000326390.19993.0d
Systematic Review of the Empirical Evidence of Study Publication Bias and Outcome Reporting Bias
Dwan, K., Altman, D. G., Arnaiz, J. A., Bloom, J., Chan, A. -W., Cronin, E., . . . Williamson, P. R. (2008). Systematic Review of the Empirical Evidence of Study Publication Bias and Outcome Reporting Bias. PLOS ONE, 3(8). doi:10.1371/journal.pone.0003081
Modelling the bilateral symmetry of caries incidence
Burnside, G., Pine, C. M., & Williamson, P. R. (2008). Modelling the bilateral symmetry of caries incidence. CARIES RESEARCH, 42(4), 291-296. doi:10.1159/000148161
Two-year placebo-controlled trial of botulinum toxin A for leg spasticity in cerebral palsy
Moore, A. P., Ade-Hall, R. A., Smith, C. T., Rosenbloom, L., Walsh, H. P. J., Mohamed, K., & Williamson, P. R. (2008). Two-year placebo-controlled trial of botulinum toxin A for leg spasticity in cerebral palsy. NEUROLOGY, 71(2), 122-128. doi:10.1212/01.wnl.0000316801.74683.c0
A randomized controlled clinical trial of 2295 ultrasound-guided embryo transfers
Drakeley, A. J., Jorgensen, A., Sklavounos, J., Aust, T., Gazvani, R., Williamson, P., & Kingsland, C. R. (2008). A randomized controlled clinical trial of 2295 ultrasound-guided embryo transfers. HUMAN REPRODUCTION, 23(5), 1101-1106. doi:10.1093/humrep/den064
Cervical stitch (cerclage) for preventing pregnancy loss: individual patient data meta-analysis - Author's reply
Jorgensen, A. L., Alfirevic, Z., Smith, C. T., & Williamson, P. R. (2008). Cervical stitch (cerclage) for preventing pregnancy loss: individual patient data meta-analysis - Author's reply. BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY, 115(6), 798-799. doi:10.1111/j.1471-0528.2008.01689.x
A systematic review of studies that aim to determine which outcomes to measure in clinical trials in children
Sinha, I., Jones, L., Smyth, R. L., & Williamson, P. R. (2008). A systematic review of studies that aim to determine which outcomes to measure in clinical trials in children. PLOS MEDICINE, 5(4), 569-578. doi:10.1371/journal.pmed.0050096
Cervical Stitch (Cerclage) for Preventing Pregnancy Loss: Individual Patient Data Meta-Analysis
Jorgensen, A. L., Alfirevic, Z., Smith, C. T., & Williamson, P. R. (2008). Cervical Stitch (Cerclage) for Preventing Pregnancy Loss: Individual Patient Data Meta-Analysis. Obstetrical & Gynecological Survey, 63(3), 135-136. doi:10.1097/01.ogx.0000305196.42050.6e
Expression of the uptake drug transporter hOCT1 is an important clinical determinant of the response to imatinib in chronic myeloid leukemia
Wang, L., Giannoudis, A., Lane, S., Williamson, P., Pirmohamed, M., & Clark, R. E. (2008). Expression of the uptake drug transporter hOCT1 is an important clinical determinant of the response to imatinib in chronic myeloid leukemia. CLINICAL PHARMACOLOGY & THERAPEUTICS, 83(2), 258-264. doi:10.1038/sj.clpt.6100268
A systematic review of studies that aim to determine which outcomes to measure in clinical trials in children.
Sinha, I., Jones, L., Smyth, R. L., & Williamson, P. R. (2008). A systematic review of studies that aim to determine which outcomes to measure in clinical trials in children.. PLoS Medicine, 5(4), e96.
Expression of the uptake drug transporter hOCT1 is an important clinical determinant of the response to imatinib in chronic myeloid leukemia
Wang, L., Giannoudis, A., Lane, S., Williamson, P., Pirmohamed, M., & Clark, R. E. (2008). Expression of the uptake drug transporter hOCT1 is an important clinical determinant of the response to imatinib in chronic myeloid leukemia. Clinical Pharmacology and Therapeutics, 83(2), 258-264. doi:10.1038/sj.clpt.6100268
2007
A comparison of methods for fixed effects meta-analysis of individual patient data with time to event outcomes
Smith, C. T., & Williamson, P. R. (2007). A comparison of methods for fixed effects meta-analysis of individual patient data with time to event outcomes. CLINICAL TRIALS, 4(6), 621-630. doi:10.1177/1740774507085276
Cervical stitch (cerclage) for preventing pregnancy loss: Individual patient data meta-analysis
Jorgensen, A. L., Alfirevic, Z., Smith, C. T., & Williamson, P. R. (2007). Cervical stitch (cerclage) for preventing pregnancy loss: Individual patient data meta-analysis. BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY, 114(12), 1460-1476. doi:10.1111/j.1471-0528.2007.01515.x
Individual patient data meta-analyses compared with meta-analyses based on aggregate data
Clarke, M. J., Stewart, L., Tierney, J., & Williamson, P. R. (n.d.). Individual patient data meta-analyses compared with meta-analyses based on aggregate data. doi:10.1002/14651858.mr000007.pub2
The association between polymorphisms in <i>RLIP76</i> and drug response in epilepsy
Leschziner, G. D., Jorgensen, A. L., Andrews, T., Williamson, P. R., Marson, A. G., Coffey, A. J., . . . Pirmohamed, M. (2007). The association between polymorphisms in <i>RLIP76</i> and drug response in epilepsy. PHARMACOGENOMICS, 8(12), 1715-1722. doi:10.2217/14622416.8.12.1715
Multiple treatment comparisons in epilepsy monotherapy trials
Smith, C. T., Marson, A. G., Chadwick, D. W., & Williamson, P. R. (2007). Multiple treatment comparisons in epilepsy monotherapy trials. TRIALS, 8. doi:10.1186/1745-6215-8-34
A randomised controlled trial examining the longer-term outcomes of standard versus new antiepileptic drugs. The SANAD trial.
Marson, A. G., Appleton, R., Baker, G. A., Chadwick, D. W., Doughty, J., Eaton, B., . . . Williamson, P. R. (2007). A randomised controlled trial examining the longer-term outcomes of standard versus new antiepileptic drugs. The SANAD trial.. Health technology assessment (Winchester, England), 11(37), iii-134. doi:10.3310/hta11370
The influence of competing-risks setting on the choice of hypothesis test for treatment effect
Williamson, P. R., Kolamunnage-Dona, R., & Smith, C. T. (2007). The influence of competing-risks setting on the choice of hypothesis test for treatment effect. BIOSTATISTICS, 8(4), 689-694. Retrieved from https://www.webofscience.com/
The application of multilevel modelling to dental caries data
Burnside, G., Pine, C. M., & Williamson, P. R. (2007). The application of multilevel modelling to dental caries data. STATISTICS IN MEDICINE, 26(22), 4139-4149. doi:10.1002/sim.2859
Risk factors for complication following ERCP; results of a large-scale, prospective multicenter study
Williams, E. J., Taylor, S., Fairclough, P., Hamlyn, A., Logan, R. F., Martin, D., . . . Lombard, M. (2007). Risk factors for complication following ERCP; results of a large-scale, prospective multicenter study. ENDOSCOPY, 39(9), 793-801. doi:10.1055/s-2007-966723
Old versus new antiepileptic drugs: the SANAD study - Reply
Marson, A. G., Tudur-Smith, C., Williamson, P. R., & Chadwick, D. W. (2007). Old versus new antiepileptic drugs: the SANAD study - Reply. LANCET, 370(9584), 315-316. doi:10.1016/S0140-6736(07)61154-4
Anthelmintic drugs for treating worms in children: effects on growth and cognitive performance (Withdrawn Paper. 2007, art. no. CD000371)
Dickson, R., Awasthi, S., Demellweek, C., & Williamson, P. (2007). Anthelmintic drugs for treating worms in children: effects on growth and cognitive performance (Withdrawn Paper. 2007, art. no. CD000371). COCHRANE DATABASE OF SYSTEMATIC REVIEWS, (2). doi:10.1002/14651858.CD000371.pub2
Are we meeting the standards set for endoscopy? Results of a large-scale prospective survey of endoscopic retrograde cholangio-pancreatograph practice
Williams, E. J., Taylor, S., Fairclough, P., Hamlyn, A., Logan, R. F., Martin, D., . . . Lombard, M. (2007). Are we meeting the standards set for endoscopy? Results of a large-scale prospective survey of endoscopic retrograde cholangio-pancreatograph practice. GUT, 56(6), 821-829. doi:10.1136/gut.2006.097543
Application and investigation of a bound for outcome reporting bias
Williamson, P. R., & Gamble, C. (2007). Application and investigation of a bound for outcome reporting bias. TRIALS, 8. doi:10.1186/1745-6215-8-9
The SANAD study of effectiveness of carbamazepine, gabapentin, lamotrigine, oxcarbazepine, or topiramate for treatment of partial epilepsy: an unblinded randomised controlled trial
Marson, A. G., Al-Kharusi, A. M., Alwaidh, M., Appleton, R., Baker, G. A., Chadwick, D. W., . . . Williamson, P. R. (2007). The SANAD study of effectiveness of carbamazepine, gabapentin, lamotrigine, oxcarbazepine, or topiramate for treatment of partial epilepsy: an unblinded randomised controlled trial. LANCET, 369(9566), 1000-1015. doi:10.1016/S0140-6736(07)60460-7
The SANAD study of effectiveness of valproate, lamotrigine, or topiramate for generalised and unclassifiable epilepsy: an unblinded randomised controlled trial
Marson, A. G., Al-Kharusi, A. M., Alwaidh, M., Appleton, R., Baker, G. A., Chadwick, D. W., . . . Williamson, P. R. (2007). The SANAD study of effectiveness of valproate, lamotrigine, or topiramate for generalised and unclassifiable epilepsy: an unblinded randomised controlled trial. LANCET, 369(9566), 1016-1026. doi:10.1016/S0140-6736(07)60461-9
Application and investigation of a bound for outcome reporting bias.
Williamson, P. R., & Gamble, C. (2007). Application and investigation of a bound for outcome reporting bias.. Trials, 8, 9. doi:10.1186/1745-6215-8-9
Interventions for helping people recognise early signs of recurrence in bipolar disorder
Morriss, R. K., Faizal, M. A., Jones, A. P., Williamson, P. R., Bolton, C., & McCarthy, J. P. (2007). Interventions for helping people recognise early signs of recurrence in bipolar disorder. COCHRANE DATABASE OF SYSTEMATIC REVIEWS, (1). doi:10.1002/14651858.CD004854.pub2
A randomised controlled trial examining the longer-term outcomes of standard versus new antiepileptic drugs. The SANAD trial
Marson, A. G., Appleton, R., Baker, G. A., Chadwick, D. W., Doughty, J., Eaton, B., . . . Williamson, P. R. (2007). A randomised controlled trial examining the longer-term outcomes of standard versus new antiepileptic drugs. The SANAD trial. HEALTH TECHNOLOGY ASSESSMENT, 11(37), IX-+. Retrieved from https://www.webofscience.com/
A randomised controlled trial of postoperative radiotherapy following breast-conserving surgery in a minimum-risk older population. The PRIME trial.
Prescott, R. J., Kunkler, I. H., Williams, L. J., King, C. C., Jack, W., van der Pol, M., . . . Cairns, J. (2007). A randomised controlled trial of postoperative radiotherapy following breast-conserving surgery in a minimum-risk older population. The PRIME trial.. Health technology assessment (Winchester, England), 11(31), 1-iv. doi:10.3310/hta11310
Efficacy of carbamazepine and valproate as monotherapy for early epilepsy and single seizures
Marson, A. G., Williamson, P. R., Taylor, S., Maguire, M., & Chadwick, D. W. (2007). Efficacy of carbamazepine and valproate as monotherapy for early epilepsy and single seizures. Neurology, 67(10), 1872-1875.
Importance of competing risks in the analysis of anti-epileptic drug failure
Williamson, P. R., Smith, C. T., Sander, J. W., & Marson, A. G. (2007). Importance of competing risks in the analysis of anti-epileptic drug failure. TRIALS, 8. doi:10.1186/1745-6215-8-12
Metformin decreases serum B<sub>12</sub> concentrations in a dose-dependent fashion.: Is there a case for routine monitoring?
Constable, S., Lane, S., Vora, J., Edwards, G., Williamson, P., & Pirmohamed, M. (2007). Metformin decreases serum B<sub>12</sub> concentrations in a dose-dependent fashion.: Is there a case for routine monitoring?. In BRITISH JOURNAL OF CLINICAL PHARMACOLOGY Vol. 63 (pp. 791). Retrieved from https://www.webofscience.com/
2006
Efficacy of carbamazepine and valproate as monotherapy for early epilepsy and single seizures
Marson, A. G., Williamson, P. R., Taylor, S., Maguire, M., & Chadwick, D. W. (2006). Efficacy of carbamazepine and valproate as monotherapy for early epilepsy and single seizures. NEUROLOGY, 67(10), 1872-1875. doi:10.1212/01.wnl.0000244421.73986.09
Clinical and functional evidence that drug transporter expression dictates the response to imatinib in chronic myeloid leukaemia.
Wang, L., Giannoudis, A., Lane, S., Williamson, P. R., Pirmohamed, M., & Clark, R. E. (2006). Clinical and functional evidence that drug transporter expression dictates the response to imatinib in chronic myeloid leukaemia.. In BLOOD Vol. 108 (pp. 608A-609A). doi:10.1182/blood.V108.11.2145.2145
Portosystemic shunts versus endoscopic therapy for variceal rebleeding in patients with cirrhosis
Khan, S., Smith, T. C., Williamson, P., & Sutton, R. (2006). Portosystemic shunts versus endoscopic therapy for variceal rebleeding in patients with cirrhosis. COCHRANE DATABASE OF SYSTEMATIC REVIEWS, (4). doi:10.1002/14651858.CD000553.pub2