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Professor Paula Williamson

Contact

P.R.Williamson@liverpool.ac.uk

+44 (0)151 794 9758

Research

Research grants

PIROUETTE A randomised, double-blind, placebo-controlled, phase 2 study of the efficacy and safety of PIRfenidOne in patients with heart failUre and preserved lEfT venTricular Ejection fraction

DEPARTMENT OF HEALTH & SOCIAL CARE (UK)

February 2017 - February 2021

A Randomised Controlled Trial of adalimumab versus pamidronate in Chronic Recurrent Multifocal Osteomyelitis (CRMO) using a Bayesian Design

ARTHRITIS RESEARCH UK

June 2016 - March 2021

Maximising the value of the UK IBD Registry for service delivery, audit and research

NAT ASSOC FOR COLITIS & CROHNS DISEASE (UK)

August 2015 - March 2019

NAMASTE - A cluster randomised trial of the Namaste care intervention to improve the quality of life for people with advanced dementia living in long term nursing care facilities

DEPARTMENT OF HEALTH & SOCIAL CARE (UK)

December 2016 - March 2019

Methods for Patient and Public Involvement in Clinical Trials: A Research Priority and Agenda Setting Exercise.

MEDICAL RESEARCH COUNCIL

October 2015 - May 2017

CORBEL Coordinating Research Infrastructures Building Enduring Life-science services

EUROPEAN COMMISSION

September 2015 - May 2020

Development of an interactive website for outcome reporting bias research

MEDICAL RESEARCH COUNCIL

July 2015 - June 2016

Feasibility of conducting a randomised controlled trial to examine the benefit of bilateral cochlear implantation compared with unilateral cochlear implantation in adults with severe to profound deafness

DEPARTMENT OF HEALTH & SOCIAL CARE (UK)

April 2017 - August 2019

Changing Agendas on Sleep, Treatment and Learning in Childhood Epilepsy (CASTLE)

DEPARTMENT OF HEALTH & SOCIAL CARE (UK)

May 2017 - July 2024

Methods to assess and improve the uptake of core outcome sets - PhD Studentship for Karen Barnes

MEDICAL RESEARCH COUNCIL

May 2015 - July 2021

2014 allocation - Wellcome ISSF non clinical fellowships

WELLCOME TRUST (UK)

May 2015 - October 2018

A study to determine the feasibility of undertaking a trial on the use of non-invasive ventilation in the management of infants with bronchiolitis - NOVEMBR

DEPARTMENT OF HEALTH & SOCIAL CARE (UK)

February 2016 - September 2018

MIROR Methods in research on research

EUROPEAN COMMISSION

March 2016 - February 2020

The iBRA (implant Breast Reconstruction evAluation) study – A prospective multicentre cohort study to inform the feasibility and conduct a pragmatic randomised clinical trial comparing new techniques of implantbased breast reconstruction

DEPARTMENT OF HEALTH & SOCIAL CARE (UK)

June 2015 - May 2018

Steroid Induction Regimen for Juvenile Idiopathic Arthritis (SIRJIA)

DEPARTMENT OF HEALTH & SOCIAL CARE (UK)

January 2016 - March 2019

Development of New Mathematical Sciences Capabilities for Healthcare Technologies

ENGINEERING & PHYSICAL SCIENCES RESEARCH COUNCIL

December 2015 - April 2021

What might a global health trials methodology research agenda look like?

MEDICAL RESEARCH COUNCIL

September 2016 - August 2017

Long COVID Core Outcome Set (LC-COS) project

DEPARTMENT OF HEALTH & SOCIAL CARE (UK)

August 2021 - November 2022

A randomised open label trial to assess change in respiratory function for people with cystic fibrosis (pwCF) established on triple combination therapy (Kaftrio™) after rationalisation of nebulised mucoactive therapies (the CF STORM trial)

DEPARTMENT OF HEALTH & SOCIAL CARE (UK)

February 2021 - January 2026

Development of a Core Outcome Set for Lyme Disease

LYME DISEASE ACTION (UK)

April 2021 - December 2024

Academia and Industry United Innovation and Treatment for Tuberculosis ( UNITE4TB)

EUROPEAN COMMISSION

June 2021 - May 2028

Better Care Northern Partnership

HEALTH DATA RESEARCH UK - HDRUK (UK)

May 2020 - March 2028

Alignment, Harmonisation, and Results: translating Core Outcome Measures to Improve Care (COM-IC) for People Living with Dementia into Australian practice

NATIONAL HEALTH AND MEDICAL RESEARCH COUNCIL (AUSTRALIA)

June 2021 - November 2024

Addressing high priority methodological questions for the trials community to use routinely-collected healthcare data

HEALTH DATA RESEARCH UK - HDRUK (UK)

June 2022 - March 2023

are2Care: PED4PED - People with Epilepsy sharing Data for care with Paramedics and Emergency Department staff

UK RESEARCH AND INNOVATION

February 2019 - March 2020

A randomised, double-blind, placebo-controlled, phase 2 evaluation of the efficacy and mechanism of trientine in patients with hypertrophic cardiomyopathy TEMPEST

DEPARTMENT OF HEALTH & SOCIAL CARE (UK)

January 2020 - December 2024

DECIDE study: Dapagliflozin Pragmatic Randomized Trial

MEDICINES & HEALTHCARE REGULATORY AGENCY (MHRA) (UK)

April 2018 - October 2024

Children Growing up in Liverpool (C-GULL)

WELLCOME TRUST (UK)

October 2020 - December 2029

Core Outcome Measures in Effectiveness Trials (COMET Initiative)

MEDICAL RESEARCH COUNCIL

September 2018 - July 2019

Can Vitamin D Supplementation in Patients with Crohn's Disease Improve Symptoms as an Adjunct Therapy: D-CODE

DEPARTMENT OF HEALTH & SOCIAL CARE (UK)

May 2018 - October 2021

Evaluation of digital health interventions: workshop and “Issues to consider” document

MEDICAL RESEARCH COUNCIL

August 2019 - December 2019

Research Capability Funding for Statistical Support

ROYAL LIVERPOOL AND BROADGREEN UNIVERSITY HOSPITALS NHS TRUST (UK)

April 2017 - March 2023

A randomised controlled trial assessing Desensitisation to cow's milk, following partially or extensivelyhydrolysed formulae feeding REgimens, in children with Allergy to cow's Milk (DREAM)

DEPARTMENT OF HEALTH & SOCIAL CARE (UK)

August 2019 - April 2028

Renewal of the Network of Hubs for Trials Methodology Research

MEDICAL RESEARCH COUNCIL

October 2016 - December 2019

NIHR ARC 2 national social care implementation projects

DEPARTMENT OF HEALTH & SOCIAL CARE (UK), LCCG - LIVERPOOL CLINICAL COMMISSIONING GROUP (UK)

October 2019 - March 2026

Extending ORRCA to create a central resource for retention research within clinical trials (ORRCA 2)

MEDICAL RESEARCH COUNCIL

June 2018 - November 2019

Trials Methodology Research Partnership (TMRP)

MEDICAL RESEARCH COUNCIL

June 2019 - January 2023

Development of a core outcome set for informed consent, clinical trials and treatment policy in patients with anal cancer

DEPARTMENT OF HEALTH & SOCIAL CARE (UK)

October 2015 - September 2017

MICA: Towards using historical data for research prioritisation in children

MEDICAL RESEARCH COUNCIL

March 2015 - February 2018

Assessing the efficacy and safety of methotrexate vs ciclosporin in the treatment of severe atopic eczema in children: the TREatment of severe Atopic eczema in children Taskforce (TREAT) randomised controlled trial

DEPARTMENT OF HEALTH & SOCIAL CARE (UK)

February 2015 - June 2023

A phase II trial of tocilizumab in anti-TNF refractory patients with JIA associated uvetis

ARTHRITIS RESEARCH UK

February 2015 - March 2020

The Cystic Fibrosis (CF) Anti-Staphylococcal Antibiotic Prophylaxis Trial (CF-START)

DEPARTMENT OF HEALTH & SOCIAL CARE (UK)

July 2016 - July 2028

Core Outcome Set for intervention trials in Postpartum Haemorrhage

BRITISH MEDICAL ASSOCIATION (UK)

September 2014 - August 2017

TOPS: Timing of Primary Surgery for Cleft Palate (renewal)

NATIONAL INSTITUTES OF HEALTH (USA)

July 2016 - June 2021

A randomised controlled trial to evaluate the clinical and cost effectiveness of a peer supported self-management intervention for relatives of people with psychosis or bipolar disorder: Relatives Education and Coping Toolkit (REACT)

DEPARTMENT OF HEALTH & SOCIAL CARE (UK)

October 2015 - September 2018

Side Lying Upper airway Maintenance in Babies Requiring Surgery for cleft palate repair (SLUMBRS)

DEPARTMENT OF HEALTH & SOCIAL CARE (UK)

June 2014 - May 2017

improving orAl health in Cleft lip and/Or palate: a health pRomotion iNtervention for children and parents (ACORN)

DEPARTMENT OF HEALTH & SOCIAL CARE (UK)

January 2015 - August 2017

Wellcome VIP Award

WELLCOME TRUST (UK)

October 2006 - September 2007

A prospective study of the aPTT waveform and lipoprotein-complexed C reactive protein assays in the early diagnosis and prognosis of sepsis

DEPARTMENT OF HEALTH & SOCIAL CARE (UK)

July 2011 - December 2012

Use of the electronic health record in the design and conduct of clinical trials

MEDICAL RESEARCH COUNCIL

November 2013 - September 2016

Variability in response to warfarin: a prospective analysis of pharmacogenetic and environmental factors.

DEPARTMENT OF HEALTH & SOCIAL CARE (UK)

September 2004 - October 2009

Technology Assessment Reviews (TARS).

DEPARTMENT OF HEALTH & SOCIAL CARE (UK)

March 2001 - March 2011

An RCT of longer-term clinical outcomes and cost effectiveness of standard and new antiepileptic drugs.

DEPARTMENT OF HEALTH & SOCIAL CARE (UK)

September 1998 - October 2007

Medicines for Children (MCRN) Clinical Trials Unit.

DEPARTMENT OF HEALTH & SOCIAL CARE (UK)

April 2005 - March 2010

Medicines for Children Research Network Clinical Trials Unit

DEPARTMENT OF HEALTH & SOCIAL CARE (UK)

April 2010 - March 2015

A pragmatic randomised controlled trial comparing the effectiveness and cost effectiveness of levetiracetam and zonisamide versus standard treatments for epilepsy: a comparison of Standard And New Antiepileptic Drugs (SANAD-II)

DEPARTMENT OF HEALTH & SOCIAL CARE (UK)

June 2012 - November 2019

Health R&D NoW.

DEPARTMENT OF HEALTH & SOCIAL CARE (UK)

April 2005 - March 2010

Clinical trial monitoring: establishing best UK practice?

MEDICAL RESEARCH COUNCIL

September 2011 - May 2013

Co-ordinating Centre of the UK Medicines for Children Research Network (MCRN.

DEPARTMENT OF HEALTH & SOCIAL CARE (UK)

April 2005 - March 2010

UK Lung Cancer Screening Trial (UKLS) - feasibility study and protocol development.

DEPARTMENT OF HEALTH & SOCIAL CARE (UK)

November 2008 - April 2009

DESIRE

EUROPEAN COMMISSION

October 2013 - September 2018

NIHR Medicines for Children Research Network

DEPARTMENT OF HEALTH & SOCIAL CARE (UK), KING'S COLLEGE LONDON (UK)

April 2010 - March 2017

Service agreement for medical statistics.

ROYAL LIVERPOOL AND BROADGREEN UNIVERSITY HOSPITALS NHS TRUST (UK)

July 2003 - March 2007

Research assistant in medical statistics.

AINTREE UNIVERSITY HOSPITAL NHS FOUNDATION TRUST (CHARITY) (UK)

October 2001 - October 2007

Driving up the quality and relevance of research-based knowledge: the COMET (Core Outcome Measures in Effectiveness Trials) Initiative

MEDICAL RESEARCH COUNCIL

November 2012 - November 2014

MYPAN: Open label randomised controlled trial of mycophenolate mofetil versus cyclphoshamide for the induction of remission of childhood polyarteritis nodosa

ARTHRITIS RESEARCH UK

July 2013 - April 2020

Duration of intravenous antibiotic therapy for children with acute osteomyelitis or septic arthritis: a feasibility study

DEPARTMENT OF HEALTH & SOCIAL CARE (UK)

October 2012 - May 2015

NIHR Clinician Scientist Award: Prediction and prevention of adverse pregnancy outcomes in women with chronic vascular disease

UNIVERSITY OF MANCHESTER (UK)

February 2014 - March 2019

GORMET

MEDICINES & HEALTHCARE REGULATORY AGENCY (MHRA) (UK)

April 2007 - March 2009

Defining patient preferences and priorities for treatment options and outcomes in epilepsy

DEPARTMENT OF HEALTH & SOCIAL CARE (UK)

June 2011 - February 2014

North West Hub for Trial Methodology Research (NWHTMR)

MEDICAL RESEARCH COUNCIL

October 2008 - August 2014

Prevention of colonisation with Pseudomonas aeruginosa for cystic fibrosis patients.

DEPARTMENT OF HEALTH & SOCIAL CARE (UK)

May 2006 - October 2006

Development of a central resource for research in recruitment in clinical trials

MEDICAL RESEARCH COUNCIL

March 2014 - November 2018

Development of a quality assessment tool for core outcome set development

MEDICAL RESEARCH COUNCIL

October 2014 - December 2017

Understanding the process and impact of within-study selective reporting bias.

MEDICAL RESEARCH COUNCIL

October 2006 - November 2008

Late social care needs of people who have had encephalitis

DEPARTMENT OF HEALTH & SOCIAL CARE (UK)

January 2021 - August 2024

UK Lung Cancer Screening Trial (UKLS)

DEPARTMENT OF HEALTH & SOCIAL CARE (UK)

April 2011 - November 2017

Multi-centre feasibility study on the efficacy of insulin-like growth factor-1 (IGF-1) and growth hormone (GH) in children with Crohn's disease-induced growth failure

CROHNS IN CHILDHOOD RESEARCH ASSOCIATION (UK)

October 2013 - November 2014

Consolidating guidelines for the prevention, detection and appraisal of reporting biases in clinical trials

MEDICAL RESEARCH COUNCIL

May 2012 - October 2013

A pragmatic randomised controlled trial of intravenous levetiracetam versus intravenous phenytoin in terminating acute, prolonged tonic-clonic seizures including convulsive status epilepticus in children, the 'EcLIPSE' Study: Emergency treatment with Levetiracetam or Phenytoin in Status Epilepticus

DEPARTMENT OF HEALTH & SOCIAL CARE (UK)

June 2014 - July 2019

NIHR Research Methods Fellowship

DEPARTMENT OF HEALTH & SOCIAL CARE (UK)

September 2012 - March 2016

COMET Health outcomes research and measurement workshop and collaboration with kyoto university

GREAT BRITAIN-SASAKAWA FOUNDATION (UK)

September 2012 - August 2013

Tissue sample collection from the ESPAC Adjuvant Trials in pancreatic cancer

CANCER RESEARCH UK (UK)

January 2007 - August 2010

Onabotulinium toxin-A versus extended release tolterodine in the management of idiopathic overactive bladder in children: A pilot randomised controlled trial OVERT

DEPARTMENT OF HEALTH & SOCIAL CARE (UK)

July 2014 - August 2018

Neighbourhood and Dementia: a mixed methods study

ECONOMIC AND SOCIAL RESEARCH COUNCIL

May 2014 - April 2019

COMET

EUROPEAN COMMISSION

October 2012 - December 2014

MerseyBeat - Best Evidence, Application and Translation of research

LIVERPOOL PRIMARY CARE TRUST (UK)

March 2008 - September 2019

DfID exact title to be defined

DEPARTMENT FOR INTERNATIONAL DEVELOPMENT (DFID) (UK)

April 2007 - March 2008

Adverse Drug Reactions in Children

DEPARTMENT OF HEALTH & SOCIAL CARE (UK)

September 2008 - September 2013

A pharmacogenomic approach to coumarin anticoagulant therapy (PACT)

EUROPEAN COMMISSION

October 2008 - March 2013

Process in recruitment to randomised controlled trials (RCTs) of medicines for children.

DEPARTMENT OF HEALTH & SOCIAL CARE (UK)

December 2007 - May 2010

Healing Foundation Clinical Trials Unit

THE SCAR FREE FOUNDATION

June 2011 - September 2020

Refractory Juvenile Myoclonoc Epilepsy Cohort (ReJuMEC)

MEDICAL RESEARCH COUNCIL

January 2009 - June 2011

Department of Health Sponsored chair in pharmacogenetics.

DEPARTMENT OF HEALTH & SOCIAL CARE (UK)

September 2007 - March 2019

Statistical methodology for longitudinal studies in clinical research.

MEDICAL RESEARCH COUNCIL

September 2005 - August 2009

Skin to skin.

WARRINGTON HOSPITAL NHS TRUST

January 2001 - March 2004

North West Research Design Services (Phase 2).

DEPARTMENT OF HEALTH & SOCIAL CARE (UK)

April 2015 - September 2018

Phase IIa, randomised, open label, controlled trial of rostuvastatin for the prevention of aminoglycoside-induced kidney toxicity in children with cystic fibrosis (PROteKT)

THE MOULTON CHARITABLE FOUNDATION (UK)

June 2014 - January 2018

Metformin and genetic polymorphisms of organic cation transporters.

ROYAL LIVERPOOL AND BROADGREEN UNIVERSITY HOSPITALS NHS TRUST (UK)

May 2005 - December 2008

Multi-centre randomised control trial comparing the clinical and cost effectiveness of trans-foraminal epidural steroid injection to surgical microdiscectomy for the treatment of chronic radicular pain secondary to prolapsed intervertebral disc herniation. (NErve Rootblock VErsus Surgery; NERVES)

DEPARTMENT OF HEALTH & SOCIAL CARE (UK)

June 2014 - December 2020

MRC North West Hub for Trials Methodology Research

MEDICAL RESEARCH COUNCIL

October 2013 - September 2018

Recruitment and retention in clinical trials: current knowledge and future directions for research, the recruitment and retention workshop

MEDICAL RESEARCH COUNCIL

September 2012 - August 2013

PACIFICO Phase III multicentre trial comparing two different Rituximab-Chemotherapy induction regimens for Follicular Lymphoma in Older patients (PACIFIC)

CANCER RESEARCH UK (UK)

November 2008 - July 2021

MASCOT

DEPARTMENT OF HEALTH & SOCIAL CARE (UK)

July 2007 - September 2012

Research Associate in Medical Statistics.

MERSEY CARE NHS FOUNDATION TRUST (UK)

April 2004 - March 2008

ORBIT II: Outcome Reporting Bias In Trials

MEDICAL RESEARCH COUNCIL

June 2012 - December 2013

A randomised controlled trial of Amnioinfusion versus conservative management In very early preterm premature rupture of membranes AMIPROM

LIVERPOOL WOMEN'S NHS FOUNDATION TRUST (UK)

January 2009 - October 2012

Adverse Drug Reactions in Children.

DEPARTMENT OF HEALTH & SOCIAL CARE (UK)

December 2007 - April 2013

Research Fellow in Medical Statistics

ROYAL LIVERPOOL CHILDREN'S NHS TRUST (CHARITABLE) (UK)

October 2000 - December 2020

MAGnesium Nebuliser Trial (MAGNET) a randomised, placebo controlled study of nebulised magnesium in acute severe asthma in children.

DEPARTMENT OF HEALTH & SOCIAL CARE (UK)

August 2010 - April 2014

Agreeing current good practice for clinical trial data sharing

MEDICAL RESEARCH COUNCIL

October 2013 - September 2014

Introducing personalised risk based intervals in screening for diabetic retinopathy: development, implementation and assessment of safety, cost-effectiveness and patient experience (ISDR study)

DEPARTMENT OF HEALTH & SOCIAL CARE (UK)

February 2013 - April 2021

Pharmacogenetics of GABAergic mechanisms of benefit and harm in epilepsy.

DEPARTMENT OF HEALTH & SOCIAL CARE (UK)

February 2005 - November 2010

Further understanding of medical conditions that can impact on child health in general and child dental health in particular.

CHESHIRE & MERSEYSIDE NHS WORKFORCE DEV CONFED (UK)

November 2004 - June 2007

North West Research Design Services

DEPARTMENT OF HEALTH & SOCIAL CARE (UK)

April 2010 - September 2018

TAILoR (TelmisArtan and InsuLin Resistance in HIV): A dose-ranging Phase II randomised open trial of telmistartan as a strategy for the reduction of insulin resistance in HIV-positive individuals on Combination Antiretroviral Therapy (CART)

DEPARTMENT OF HEALTH & SOCIAL CARE (UK)

January 2012 - February 2020

MOMENT The management of otitis media with effusion (OME) in children with cleft palate

CENTRAL MANCHESTER TEACHING HOSPITALS (UK)

August 2012 - August 2013

NIHR Senior Investigator Award- Funding allocation to Alder Hey and Paula Williamson

ALDER HEY CHILDREN'S NHS FOUNDATION TRUST (UK), DEPARTMENT OF HEALTH & SOCIAL CARE (UK)

April 2014 - December 2026

Workshop on the design and analysis of clinical trials in Head and Neck Cancer

MEDICAL RESEARCH COUNCIL

June 2013 - April 2014