Research
Research groups
- Medical Statistics
- Joint Modelling Group
- Child and Reproductive Health
- Health Technology Assessment
Research grants
PIROUETTE A randomised, double-blind, placebo-controlled, phase 2 study of the efficacy and safety of PIRfenidOne in patients with heart failUre and preserved lEfT venTricular Ejection fraction
DEPARTMENT OF HEALTH & SOCIAL CARE (UK)
February 2017 - February 2021
A Randomised Controlled Trial of adalimumab versus pamidronate in Chronic Recurrent Multifocal Osteomyelitis (CRMO) using a Bayesian Design
ARTHRITIS RESEARCH UK
June 2016 - March 2021
Maximising the value of the UK IBD Registry for service delivery, audit and research
NAT ASSOC FOR COLITIS & CROHNS DISEASE (UK)
August 2015 - March 2019
NAMASTE - A cluster randomised trial of the Namaste care intervention to improve the quality of life for people with advanced dementia living in long term nursing care facilities
DEPARTMENT OF HEALTH & SOCIAL CARE (UK)
December 2016 - March 2019
Methods for Patient and Public Involvement in Clinical Trials: A Research Priority and Agenda Setting Exercise.
MEDICAL RESEARCH COUNCIL
October 2015 - May 2017
CORBEL Coordinating Research Infrastructures Building Enduring Life-science services
EUROPEAN COMMISSION
September 2015 - May 2020
Development of an interactive website for outcome reporting bias research
MEDICAL RESEARCH COUNCIL
July 2015 - June 2016
Feasibility of conducting a randomised controlled trial to examine the benefit of bilateral cochlear implantation compared with unilateral cochlear implantation in adults with severe to profound deafness
DEPARTMENT OF HEALTH & SOCIAL CARE (UK)
April 2017 - August 2019
Changing Agendas on Sleep, Treatment and Learning in Childhood Epilepsy (CASTLE)
DEPARTMENT OF HEALTH & SOCIAL CARE (UK)
May 2017 - July 2024
Methods to assess and improve the uptake of core outcome sets - PhD Studentship for Karen Barnes
MEDICAL RESEARCH COUNCIL
May 2015 - July 2021
2014 allocation - Wellcome ISSF non clinical fellowships
WELLCOME TRUST (UK)
May 2015 - October 2018
A study to determine the feasibility of undertaking a trial on the use of non-invasive ventilation in the management of infants with bronchiolitis - NOVEMBR
DEPARTMENT OF HEALTH & SOCIAL CARE (UK)
February 2016 - September 2018
MIROR Methods in research on research
EUROPEAN COMMISSION
March 2016 - February 2020
The iBRA (implant Breast Reconstruction evAluation) study – A prospective multicentre cohort study to inform the feasibility and conduct a pragmatic randomised clinical trial comparing new techniques of implantbased breast reconstruction
DEPARTMENT OF HEALTH & SOCIAL CARE (UK)
June 2015 - May 2018
Steroid Induction Regimen for Juvenile Idiopathic Arthritis (SIRJIA)
DEPARTMENT OF HEALTH & SOCIAL CARE (UK)
January 2016 - March 2019
Development of New Mathematical Sciences Capabilities for Healthcare Technologies
ENGINEERING & PHYSICAL SCIENCES RESEARCH COUNCIL
December 2015 - April 2021
What might a global health trials methodology research agenda look like?
MEDICAL RESEARCH COUNCIL
September 2016 - August 2017
Long COVID Core Outcome Set (LC-COS) project
DEPARTMENT OF HEALTH & SOCIAL CARE (UK)
August 2021 - November 2022
A randomised open label trial to assess change in respiratory function for people with cystic fibrosis (pwCF) established on triple combination therapy (Kaftrio™) after rationalisation of nebulised mucoactive therapies (the CF STORM trial)
DEPARTMENT OF HEALTH & SOCIAL CARE (UK)
February 2021 - January 2026
Development of a Core Outcome Set for Lyme Disease
LYME DISEASE ACTION (UK)
April 2021 - December 2024
Academia and Industry United Innovation and Treatment for Tuberculosis ( UNITE4TB)
EUROPEAN COMMISSION
June 2021 - May 2028
Better Care Northern Partnership
HEALTH DATA RESEARCH UK - HDRUK (UK)
May 2020 - March 2028
Alignment, Harmonisation, and Results: translating Core Outcome Measures to Improve Care (COM-IC) for People Living with Dementia into Australian practice
NATIONAL HEALTH AND MEDICAL RESEARCH COUNCIL (AUSTRALIA)
June 2021 - November 2024
Addressing high priority methodological questions for the trials community to use routinely-collected healthcare data
HEALTH DATA RESEARCH UK - HDRUK (UK)
June 2022 - March 2023
are2Care: PED4PED - People with Epilepsy sharing Data for care with Paramedics and Emergency Department staff
UK RESEARCH AND INNOVATION
February 2019 - March 2020
A randomised, double-blind, placebo-controlled, phase 2 evaluation of the efficacy and mechanism of trientine in patients with hypertrophic cardiomyopathy TEMPEST
DEPARTMENT OF HEALTH & SOCIAL CARE (UK)
January 2020 - December 2024
DECIDE study: Dapagliflozin Pragmatic Randomized Trial
MEDICINES & HEALTHCARE REGULATORY AGENCY (MHRA) (UK)
April 2018 - October 2024
Children Growing up in Liverpool (C-GULL)
WELLCOME TRUST (UK)
October 2020 - December 2029
Core Outcome Measures in Effectiveness Trials (COMET Initiative)
MEDICAL RESEARCH COUNCIL
September 2018 - July 2019
Can Vitamin D Supplementation in Patients with Crohn's Disease Improve Symptoms as an Adjunct Therapy: D-CODE
DEPARTMENT OF HEALTH & SOCIAL CARE (UK)
May 2018 - October 2021
Evaluation of digital health interventions: workshop and “Issues to consider” document
MEDICAL RESEARCH COUNCIL
August 2019 - December 2019
Research Capability Funding for Statistical Support
ROYAL LIVERPOOL AND BROADGREEN UNIVERSITY HOSPITALS NHS TRUST (UK)
April 2017 - March 2023
A randomised controlled trial assessing Desensitisation to cow's milk, following partially or extensivelyhydrolysed formulae feeding REgimens, in children with Allergy to cow's Milk (DREAM)
DEPARTMENT OF HEALTH & SOCIAL CARE (UK)
August 2019 - April 2028
Renewal of the Network of Hubs for Trials Methodology Research
MEDICAL RESEARCH COUNCIL
October 2016 - December 2019
NIHR ARC 2 national social care implementation projects
DEPARTMENT OF HEALTH & SOCIAL CARE (UK), LCCG - LIVERPOOL CLINICAL COMMISSIONING GROUP (UK)
October 2019 - March 2026
Extending ORRCA to create a central resource for retention research within clinical trials (ORRCA 2)
MEDICAL RESEARCH COUNCIL
June 2018 - November 2019
Trials Methodology Research Partnership (TMRP)
MEDICAL RESEARCH COUNCIL
June 2019 - January 2023
Development of a core outcome set for informed consent, clinical trials and treatment policy in patients with anal cancer
DEPARTMENT OF HEALTH & SOCIAL CARE (UK)
October 2015 - September 2017
MICA: Towards using historical data for research prioritisation in children
MEDICAL RESEARCH COUNCIL
March 2015 - February 2018
Assessing the efficacy and safety of methotrexate vs ciclosporin in the treatment of severe atopic eczema in children: the TREatment of severe Atopic eczema in children Taskforce (TREAT) randomised controlled trial
DEPARTMENT OF HEALTH & SOCIAL CARE (UK)
February 2015 - June 2023
A phase II trial of tocilizumab in anti-TNF refractory patients with JIA associated uvetis
ARTHRITIS RESEARCH UK
February 2015 - March 2020
The Cystic Fibrosis (CF) Anti-Staphylococcal Antibiotic Prophylaxis Trial (CF-START)
DEPARTMENT OF HEALTH & SOCIAL CARE (UK)
July 2016 - July 2028
Core Outcome Set for intervention trials in Postpartum Haemorrhage
BRITISH MEDICAL ASSOCIATION (UK)
September 2014 - August 2017
TOPS: Timing of Primary Surgery for Cleft Palate (renewal)
NATIONAL INSTITUTES OF HEALTH (USA)
July 2016 - June 2021
A randomised controlled trial to evaluate the clinical and cost effectiveness of a peer supported self-management intervention for relatives of people with psychosis or bipolar disorder: Relatives Education and Coping Toolkit (REACT)
DEPARTMENT OF HEALTH & SOCIAL CARE (UK)
October 2015 - September 2018
Side Lying Upper airway Maintenance in Babies Requiring Surgery for cleft palate repair (SLUMBRS)
DEPARTMENT OF HEALTH & SOCIAL CARE (UK)
June 2014 - May 2017
improving orAl health in Cleft lip and/Or palate: a health pRomotion iNtervention for children and parents (ACORN)
DEPARTMENT OF HEALTH & SOCIAL CARE (UK)
January 2015 - August 2017
Wellcome VIP Award
WELLCOME TRUST (UK)
October 2006 - September 2007
A prospective study of the aPTT waveform and lipoprotein-complexed C reactive protein assays in the early diagnosis and prognosis of sepsis
DEPARTMENT OF HEALTH & SOCIAL CARE (UK)
July 2011 - December 2012
Use of the electronic health record in the design and conduct of clinical trials
MEDICAL RESEARCH COUNCIL
November 2013 - September 2016
Variability in response to warfarin: a prospective analysis of pharmacogenetic and environmental factors.
DEPARTMENT OF HEALTH & SOCIAL CARE (UK)
September 2004 - October 2009
Technology Assessment Reviews (TARS).
DEPARTMENT OF HEALTH & SOCIAL CARE (UK)
March 2001 - March 2011
An RCT of longer-term clinical outcomes and cost effectiveness of standard and new antiepileptic drugs.
DEPARTMENT OF HEALTH & SOCIAL CARE (UK)
September 1998 - October 2007
Medicines for Children (MCRN) Clinical Trials Unit.
DEPARTMENT OF HEALTH & SOCIAL CARE (UK)
April 2005 - March 2010
Medicines for Children Research Network Clinical Trials Unit
DEPARTMENT OF HEALTH & SOCIAL CARE (UK)
April 2010 - March 2015
A pragmatic randomised controlled trial comparing the effectiveness and cost effectiveness of levetiracetam and zonisamide versus standard treatments for epilepsy: a comparison of Standard And New Antiepileptic Drugs (SANAD-II)
DEPARTMENT OF HEALTH & SOCIAL CARE (UK)
June 2012 - November 2019
Health R&D NoW.
DEPARTMENT OF HEALTH & SOCIAL CARE (UK)
April 2005 - March 2010
Clinical trial monitoring: establishing best UK practice?
MEDICAL RESEARCH COUNCIL
September 2011 - May 2013
Co-ordinating Centre of the UK Medicines for Children Research Network (MCRN.
DEPARTMENT OF HEALTH & SOCIAL CARE (UK)
April 2005 - March 2010
UK Lung Cancer Screening Trial (UKLS) - feasibility study and protocol development.
DEPARTMENT OF HEALTH & SOCIAL CARE (UK)
November 2008 - April 2009
DESIRE
EUROPEAN COMMISSION
October 2013 - September 2018
NIHR Medicines for Children Research Network
DEPARTMENT OF HEALTH & SOCIAL CARE (UK), KING'S COLLEGE LONDON (UK)
April 2010 - March 2017
Service agreement for medical statistics.
ROYAL LIVERPOOL AND BROADGREEN UNIVERSITY HOSPITALS NHS TRUST (UK)
July 2003 - March 2007
Research assistant in medical statistics.
AINTREE UNIVERSITY HOSPITAL NHS FOUNDATION TRUST (CHARITY) (UK)
October 2001 - October 2007
Driving up the quality and relevance of research-based knowledge: the COMET (Core Outcome Measures in Effectiveness Trials) Initiative
MEDICAL RESEARCH COUNCIL
November 2012 - November 2014
MYPAN: Open label randomised controlled trial of mycophenolate mofetil versus cyclphoshamide for the induction of remission of childhood polyarteritis nodosa
ARTHRITIS RESEARCH UK
July 2013 - April 2020
Duration of intravenous antibiotic therapy for children with acute osteomyelitis or septic arthritis: a feasibility study
DEPARTMENT OF HEALTH & SOCIAL CARE (UK)
October 2012 - May 2015
NIHR Clinician Scientist Award: Prediction and prevention of adverse pregnancy outcomes in women with chronic vascular disease
UNIVERSITY OF MANCHESTER (UK)
February 2014 - March 2019
GORMET
MEDICINES & HEALTHCARE REGULATORY AGENCY (MHRA) (UK)
April 2007 - March 2009
Defining patient preferences and priorities for treatment options and outcomes in epilepsy
DEPARTMENT OF HEALTH & SOCIAL CARE (UK)
June 2011 - February 2014
North West Hub for Trial Methodology Research (NWHTMR)
MEDICAL RESEARCH COUNCIL
October 2008 - August 2014
Prevention of colonisation with Pseudomonas aeruginosa for cystic fibrosis patients.
DEPARTMENT OF HEALTH & SOCIAL CARE (UK)
May 2006 - October 2006
Development of a central resource for research in recruitment in clinical trials
MEDICAL RESEARCH COUNCIL
March 2014 - November 2018
Development of a quality assessment tool for core outcome set development
MEDICAL RESEARCH COUNCIL
October 2014 - December 2017
Understanding the process and impact of within-study selective reporting bias.
MEDICAL RESEARCH COUNCIL
October 2006 - November 2008
Late social care needs of people who have had encephalitis
DEPARTMENT OF HEALTH & SOCIAL CARE (UK)
January 2021 - August 2024
UK Lung Cancer Screening Trial (UKLS)
DEPARTMENT OF HEALTH & SOCIAL CARE (UK)
April 2011 - November 2017
Multi-centre feasibility study on the efficacy of insulin-like growth factor-1 (IGF-1) and growth hormone (GH) in children with Crohn's disease-induced growth failure
CROHNS IN CHILDHOOD RESEARCH ASSOCIATION (UK)
October 2013 - November 2014
Consolidating guidelines for the prevention, detection and appraisal of reporting biases in clinical trials
MEDICAL RESEARCH COUNCIL
May 2012 - October 2013
A pragmatic randomised controlled trial of intravenous levetiracetam versus intravenous phenytoin in terminating acute, prolonged tonic-clonic seizures including convulsive status epilepticus in children, the 'EcLIPSE' Study: Emergency treatment with Levetiracetam or Phenytoin in Status Epilepticus
DEPARTMENT OF HEALTH & SOCIAL CARE (UK)
June 2014 - July 2019
NIHR Research Methods Fellowship
DEPARTMENT OF HEALTH & SOCIAL CARE (UK)
September 2012 - March 2016
COMET Health outcomes research and measurement workshop and collaboration with kyoto university
GREAT BRITAIN-SASAKAWA FOUNDATION (UK)
September 2012 - August 2013
Tissue sample collection from the ESPAC Adjuvant Trials in pancreatic cancer
CANCER RESEARCH UK (UK)
January 2007 - August 2010
Onabotulinium toxin-A versus extended release tolterodine in the management of idiopathic overactive bladder in children: A pilot randomised controlled trial OVERT
DEPARTMENT OF HEALTH & SOCIAL CARE (UK)
July 2014 - August 2018
Neighbourhood and Dementia: a mixed methods study
ECONOMIC AND SOCIAL RESEARCH COUNCIL
May 2014 - April 2019
COMET
EUROPEAN COMMISSION
October 2012 - December 2014
MerseyBeat - Best Evidence, Application and Translation of research
LIVERPOOL PRIMARY CARE TRUST (UK)
March 2008 - September 2019
DfID exact title to be defined
DEPARTMENT FOR INTERNATIONAL DEVELOPMENT (DFID) (UK)
April 2007 - March 2008
Adverse Drug Reactions in Children
DEPARTMENT OF HEALTH & SOCIAL CARE (UK)
September 2008 - September 2013
A pharmacogenomic approach to coumarin anticoagulant therapy (PACT)
EUROPEAN COMMISSION
October 2008 - March 2013
Process in recruitment to randomised controlled trials (RCTs) of medicines for children.
DEPARTMENT OF HEALTH & SOCIAL CARE (UK)
December 2007 - May 2010
Healing Foundation Clinical Trials Unit
THE SCAR FREE FOUNDATION
June 2011 - September 2020
Refractory Juvenile Myoclonoc Epilepsy Cohort (ReJuMEC)
MEDICAL RESEARCH COUNCIL
January 2009 - June 2011
Department of Health Sponsored chair in pharmacogenetics.
DEPARTMENT OF HEALTH & SOCIAL CARE (UK)
September 2007 - March 2019
Statistical methodology for longitudinal studies in clinical research.
MEDICAL RESEARCH COUNCIL
September 2005 - August 2009
Skin to skin.
WARRINGTON HOSPITAL NHS TRUST
January 2001 - March 2004
North West Research Design Services (Phase 2).
DEPARTMENT OF HEALTH & SOCIAL CARE (UK)
April 2015 - September 2018
Phase IIa, randomised, open label, controlled trial of rostuvastatin for the prevention of aminoglycoside-induced kidney toxicity in children with cystic fibrosis (PROteKT)
THE MOULTON CHARITABLE FOUNDATION (UK)
June 2014 - January 2018
Metformin and genetic polymorphisms of organic cation transporters.
ROYAL LIVERPOOL AND BROADGREEN UNIVERSITY HOSPITALS NHS TRUST (UK)
May 2005 - December 2008
Multi-centre randomised control trial comparing the clinical and cost effectiveness of trans-foraminal epidural steroid injection to surgical microdiscectomy for the treatment of chronic radicular pain secondary to prolapsed intervertebral disc herniation. (NErve Rootblock VErsus Surgery; NERVES)
DEPARTMENT OF HEALTH & SOCIAL CARE (UK)
June 2014 - December 2020
MRC North West Hub for Trials Methodology Research
MEDICAL RESEARCH COUNCIL
October 2013 - September 2018
Recruitment and retention in clinical trials: current knowledge and future directions for research, the recruitment and retention workshop
MEDICAL RESEARCH COUNCIL
September 2012 - August 2013
PACIFICO Phase III multicentre trial comparing two different Rituximab-Chemotherapy induction regimens for Follicular Lymphoma in Older patients (PACIFIC)
CANCER RESEARCH UK (UK)
November 2008 - July 2021
MASCOT
DEPARTMENT OF HEALTH & SOCIAL CARE (UK)
July 2007 - September 2012
Research Associate in Medical Statistics.
MERSEY CARE NHS FOUNDATION TRUST (UK)
April 2004 - March 2008
ORBIT II: Outcome Reporting Bias In Trials
MEDICAL RESEARCH COUNCIL
June 2012 - December 2013
A randomised controlled trial of Amnioinfusion versus conservative management In very early preterm premature rupture of membranes AMIPROM
LIVERPOOL WOMEN'S NHS FOUNDATION TRUST (UK)
January 2009 - October 2012
Adverse Drug Reactions in Children.
DEPARTMENT OF HEALTH & SOCIAL CARE (UK)
December 2007 - April 2013
Research Fellow in Medical Statistics
ROYAL LIVERPOOL CHILDREN'S NHS TRUST (CHARITABLE) (UK)
October 2000 - December 2020
MAGnesium Nebuliser Trial (MAGNET) a randomised, placebo controlled study of nebulised magnesium in acute severe asthma in children.
DEPARTMENT OF HEALTH & SOCIAL CARE (UK)
August 2010 - April 2014
Agreeing current good practice for clinical trial data sharing
MEDICAL RESEARCH COUNCIL
October 2013 - September 2014
Introducing personalised risk based intervals in screening for diabetic retinopathy: development, implementation and assessment of safety, cost-effectiveness and patient experience (ISDR study)
DEPARTMENT OF HEALTH & SOCIAL CARE (UK)
February 2013 - April 2021
Pharmacogenetics of GABAergic mechanisms of benefit and harm in epilepsy.
DEPARTMENT OF HEALTH & SOCIAL CARE (UK)
February 2005 - November 2010
Further understanding of medical conditions that can impact on child health in general and child dental health in particular.
CHESHIRE & MERSEYSIDE NHS WORKFORCE DEV CONFED (UK)
November 2004 - June 2007
North West Research Design Services
DEPARTMENT OF HEALTH & SOCIAL CARE (UK)
April 2010 - September 2018
TAILoR (TelmisArtan and InsuLin Resistance in HIV): A dose-ranging Phase II randomised open trial of telmistartan as a strategy for the reduction of insulin resistance in HIV-positive individuals on Combination Antiretroviral Therapy (CART)
DEPARTMENT OF HEALTH & SOCIAL CARE (UK)
January 2012 - February 2020
MOMENT The management of otitis media with effusion (OME) in children with cleft palate
CENTRAL MANCHESTER TEACHING HOSPITALS (UK)
August 2012 - August 2013
NIHR Senior Investigator Award- Funding allocation to Alder Hey and Paula Williamson
ALDER HEY CHILDREN'S NHS FOUNDATION TRUST (UK), DEPARTMENT OF HEALTH & SOCIAL CARE (UK)
April 2014 - December 2026
Workshop on the design and analysis of clinical trials in Head and Neck Cancer
MEDICAL RESEARCH COUNCIL
June 2013 - April 2014