Publications
Selected publications
- Determination and biological relevance of serum cross-linked type I collagen <i>N</i>-telopeptide and bone-specific alkaline phosphatase in breast metastatic cancer (Journal article - 2004)
- Serglycin constitutively secreted by myeloma plasma cells is a potent inhibitor of bone mineralization <i>in vitro</i> (Journal article - 2006)
- The impact of zoledronic acid therapy in survival of lung cancer patients with bone metastasis (Journal article - 2009)
- Expression of matrix macromolecules and functional properties of breast cancer cells are modulated by the bisphosphonate zoledronic acid (Journal article - 2012)
- Targeted Inhibition of Aggrecanases Prevents Articular Cartilage Degradation and Augments Bone Mass in the STR/Ort Mouse Model of Spontaneous Osteoarthritis (Journal article - 2019)
2025
Temporomandibular joint degeneration arises spontaneously in STR/ort mice and is prevented by targeted aggrecanase inhibition.
Ooi, K., Yamamoto, K., Kobayashi, Y., Javaheri, B., Jensen, A., Kanakis, I., . . . Bou-Gharios, G. (2025). Temporomandibular joint degeneration arises spontaneously in STR/ort mice and is prevented by targeted aggrecanase inhibition.. Osteoarthritis and cartilage open, 7(2), 100599. doi:10.1016/j.ocarto.2025.100599
2024
Does lifelong dietary protein restriction contribute to the early onset of sarcopenia?
Ersoy, U., Altinpinar, A. E., Kanakis, I., Peffers, M. J., Jackson, M., Goljanek-Whysall, K., & Vasilaki, A. (2024). Does lifelong dietary protein restriction contribute to the early onset of sarcopenia?. Free Radical Biology and Medicine, 224, S81-S82. doi:10.1016/j.freeradbiomed.2024.10.177
Maternal Low-Protein Diet Impairs Skeletal Muscle Development, Inflammatory Responses, and Mitochondrial Function in Offspring: Long-Term Effects on Muscle Ageing
Altinpinar, A. E., Ersoy, U., Alameddine, M., Kanakis, I., Pekovic-Vaughan, V., Goljanek-Whysall, K., & Vasilaki, A. (2024). Maternal Low-Protein Diet Impairs Skeletal Muscle Development, Inflammatory Responses, and Mitochondrial Function in Offspring: Long-Term Effects on Muscle Ageing. Free Radical Biology and Medicine, 224, S104. doi:10.1016/j.freeradbiomed.2024.10.230
Lifelong dietary protein restriction induces denervation and skeletal muscle atrophy in mice.
Ersoy, U., Altinpinar, A. E., Kanakis, I., Alameddine, M., Gioran, A., Chondrogianni, N., . . . Vasilaki, A. (2024). Lifelong dietary protein restriction induces denervation and skeletal muscle atrophy in mice.. Free radical biology & medicine, S0891-5849(24)00648-8. doi:10.1016/j.freeradbiomed.2024.09.005
Effect of Lactational Low-Protein Diet on Skeletal Muscle during Adulthood and Ageing in Male and Female Mouse Offspring
Alameddine, M., Altinpinar, A. E., Ersoy, U., Kanakis, I., Myrtziou, I., Ozanne, S. E., . . . Vasilaki, A. (n.d.). Effect of Lactational Low-Protein Diet on Skeletal Muscle during Adulthood and Ageing in Male and Female Mouse Offspring. Nutrients, 16(17), 2926. doi:10.3390/nu16172926
Impact of Different Anti-Hyperglycaemic Treatments on Bone Turnover Markers and Bone Mineral Density in Type 2 Diabetes Mellitus Patients: A Systematic Review and Meta-Analysis.
Saadi, M. S. S., Das, R., Mullath Ullas, A., Powell, D. E., Wilson, E., Myrtziou, I., . . . Kanakis, I. (2024). Impact of Different Anti-Hyperglycaemic Treatments on Bone Turnover Markers and Bone Mineral Density in Type 2 Diabetes Mellitus Patients: A Systematic Review and Meta-Analysis.. International journal of molecular sciences, 25(14), 7988. doi:10.3390/ijms25147988
Lifelong effects of maternal low protein diet on skeletal muscle development and ageing in male offsprings
Altinpinar, A. E., Ersoy, U., Alameddine, M., Pekovic-Vaughan, V., Kanakis, I., Whysall, K. G., & Vasilaki, A. (2024). Lifelong effects of maternal low protein diet on skeletal muscle development and ageing in male offsprings. Free Radical Biology and Medicine, 218, 39. doi:10.1016/j.freeradbiomed.2024.04.142
Lifelong protein restriction induces denervation and increases proteasomal activity in skeletal muscle
Ersoy, U., Altinpinar, A. E., Alameddine, M., Kanakis, I., Peffers, M. J., Ozanne, S. E., . . . Vasilaki, A. (2024). Lifelong protein restriction induces denervation and increases proteasomal activity in skeletal muscle. Free Radical Biology and Medicine, 218, 38. doi:10.1016/j.freeradbiomed.2024.04.138
Defining the Most Potent Osteoinductive Culture Conditions for MC3T3-E1 Cells Reveals No Implication of Oxidative Stress or Energy Metabolism.
Semicheva, A., Ersoy, U., Vasilaki, A., Myrtziou, I., & Kanakis, I. (2024). Defining the Most Potent Osteoinductive Culture Conditions for MC3T3-E1 Cells Reveals No Implication of Oxidative Stress or Energy Metabolism.. International journal of molecular sciences, 25(8), 4180. doi:10.3390/ijms25084180
Defining the most potent osteoinductive culture conditions for MC3T3-E1 cells reveals no implication of oxidative stress or energy metabolism
Lifelong dietary protein restriction accelerates skeletal muscle loss and reduces muscle fibre size by impairing proteostasis and mitochondrial homeostasis.
Ersoy, U., Kanakis, I., Alameddine, M., Pedraza-Vazquez, G., Ozanne, S. E., Peffers, M. J., . . . Vasilaki, A. (2024). Lifelong dietary protein restriction accelerates skeletal muscle loss and reduces muscle fibre size by impairing proteostasis and mitochondrial homeostasis.. Redox biology, 69, 102980. doi:10.1016/j.redox.2023.102980
2023
Prolonged dietary protein restriction accelerates skeletal muscle loss and reduces muscle fibre size by impairing proteostasis and mitochondrial homeostasis
Ersoy, U., Vasilaki, A., Jackson, M., Kanakis, I., Peffers, M. J., & Goljanek-Whysall, K. (2023). Prolonged dietary protein restriction accelerates skeletal muscle loss and reduces muscle fibre size by impairing proteostasis and mitochondrial homeostasis. Free Radical Biology and Medicine, 208, S65. doi:10.1016/j.freeradbiomed.2023.10.146
Editorial: Epigenetic regulation of the musculoskeletal system in health, disease, and aging
Goljanek-Whysall, K., Tew, S., Peffers, M. J., & Kanakis, I. (2023). Editorial: Epigenetic regulation of the musculoskeletal system in health, disease, and aging. FRONTIERS IN ENDOCRINOLOGY, 14. doi:10.3389/fendo.2023.1143210
Chapter 6 The effect of maternal and early-life nutrition on redox homeostasis
Ersoy, U., Alameddine, M., Kanakis, I., Staunton, C. A., Peffers, M. J., Jackson, M. J., . . . Vasilaki, A. (2023). Chapter 6 The effect of maternal and early-life nutrition on redox homeostasis. In Modulation of Oxidative Stress (pp. 71-80). Elsevier. doi:10.1016/b978-0-443-19247-0.00002-3
Targeted inhibition of aggrecanases inhibits the progression of age-dependent cartilage degradation in a temporomandibular joint in the STR/Ort mice
Kobayashi, Y., Yamamoto, K., Kanakis, I., Yamashita, Y., Sakai, T., Jarad, F., . . . Ooi, K. (2023). Targeted inhibition of aggrecanases inhibits the progression of age-dependent cartilage degradation in a temporomandibular joint in the STR/Ort mice. In INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY Vol. 104 (pp. A9). Retrieved from https://www.webofscience.com/
The effect of maternal and early-life nutrition on redox homeostasis
Ersoy, U., Alameddine, M., Kanakis, I., Staunton, C. A., Peffers, M. J., Jackson, M. J., . . . Vasilaki, A. (2023). The effect of maternal and early-life nutrition on redox homeostasis. In Modulation of Oxidative Stress (pp. 71-80). Elsevier. doi:10.1016/b978-0-443-19247-0.00002-3
2022
MicroRNAs as central regulators of adult myogenesis and proteostasis loss in skeletal muscle aging
Kanakis, I., Myrtziou, I., Vasilaki, A., & Goljanek-Whysall, K. (2022). MicroRNAs as central regulators of adult myogenesis and proteostasis loss in skeletal muscle aging. In Proteostasis and Proteolysis (pp. 45-55). doi:10.1201/9781003048138-4
Postnatal Protein Intake as a Determinant of Skeletal Muscle Structure and Function in Mice-A Pilot Study
Giakoumaki, I., Pollock, N., Aljuaid, T., Sannicandro, A. J., Alameddine, M., Owen, E., . . . Vasilaki, A. (2022). Postnatal Protein Intake as a Determinant of Skeletal Muscle Structure and Function in Mice-A Pilot Study. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 23(15). doi:10.3390/ijms23158815
2021
Micrornas as Central Regulators of Adult Myogenesis and Proteostasis Loss in Skeletal Muscle Aging
Kanakis, I., Myrtziou, I., Vasilaki, A., & Goljanek-Whysall, K. (2021). Micrornas as Central Regulators of Adult Myogenesis and Proteostasis Loss in Skeletal Muscle Aging. In Proteostasis and Proteolysis (pp. 45-56). CRC Press. doi:10.1201/9781003048138-04
Small-RNA Sequencing Reveals Altered Skeletal Muscle microRNAs and snoRNAs Signatures in Weanling Male Offspring from Mouse Dams Fed a Low Protein Diet during Lactation
Kanakis, I., Alameddine, M., Folkes, L., Moxon, S., Myrtziou, I., Ozanne, S. E., . . . Vasilaki, A. (2021). Small-RNA Sequencing Reveals Altered Skeletal Muscle microRNAs and snoRNAs Signatures in Weanling Male Offspring from Mouse Dams Fed a Low Protein Diet during Lactation. CELLS, 10(5). doi:10.3390/cells10051166
Small-RNA sequencing reveals altered skeletal muscle microRNAs and snoRNAs signatures in weanling male offspring from mouse dams fed a low protein diet during lactation
Kanakis, I., Alameddine, M., Folkes, L., Moxon, S., Myrtziou, I., Ozanne, S., . . . Vasilaki, A. (2021). Small-RNA sequencing reveals altered skeletal muscle microRNAs and snoRNAs signatures in weanling male offspring from mouse dams fed a low protein diet during lactation. doi:10.1101/2021.02.22.432208
Cartilage-Specific Cre Recombinase Transgenes/Alleles in the Mouse
Kanakis, I., Alhashmi, M., Liu, K., Keenan, C., Mucci, L. R., Poulet, B., & Bou-Gharios, G. (2021). Cartilage-Specific Cre Recombinase Transgenes/Alleles in the Mouse. In CHONDROCYTES (Vol. 2245, pp. 23-38). doi:10.1007/978-1-0716-1119-7_3
Metalloelastase-12 is involved in the temporomandibular joint inflammatory response as well as cartilage degradation by aggrecanases in STR/Ort mice
Yamashita-Futani, Y., Jokaji, R., Ooi, K., Kobayashi, K., Kanakis, I., Liu, K., . . . Nakamura, H. (2021). Metalloelastase-12 is involved in the temporomandibular joint inflammatory response as well as cartilage degradation by aggrecanases in STR/Ort mice. BIOMEDICAL REPORTS, 14(6). doi:10.3892/br.2021.1427
2020
Low protein diet compromises the recovery of lactation-induced bone loss in female mouse dams with no effects on skeletal muscles
Kanakis, I., Alameddine, M., Scalabrin, M., van ’tHof, R., Ozanne, S., Goljanek-Whysall, K., & Vasilaki, A. (2020). Low protein diet compromises the recovery of lactation-induced bone loss in female mouse dams with no effects on skeletal muscles. Bone Reports, 13, 100685. doi:10.1016/j.bonr.2020.100685
Post-traumatic osteoarthritis development is not modified by postnatal chondrocyte deletion of <i>Ccn2</i>
Keenan, C. M., Ramos-Mucci, L., Kanakis, I., Milner, P. I., Leask, A., Abraham, D., . . . Poulet, B. (2020). Post-traumatic osteoarthritis development is not modified by postnatal chondrocyte deletion of <i>Ccn2</i>. DISEASE MODELS & MECHANISMS, 13(7). doi:10.1242/dmm.044719
Low protein intake during reproduction compromises the recovery of lactation‐induced bone loss in female mouse dams without affecting skeletal muscles
Kanakis, I., Alameddine, M., Scalabrin, M., van't Hof, R. J., Liloglou, T., Ozanne, S. E., . . . Vasilaki, A. (2020). Low protein intake during reproduction compromises the recovery of lactation‐induced bone loss in female mouse dams without affecting skeletal muscles. The FASEB Journal. doi:10.1096/fj.202001131R
Aggrecanase-selective tissue inhibitor of metalloproteinase-3 (TIMP3) protects articular cartilage in a surgical mouse model of osteoarthritis
Nakamura, H., Phoung, V., Kanakis, I., Liu, K., & Bou-Gharios, G. (2020). Aggrecanase-selective tissue inhibitor of metalloproteinase-3 (TIMP3) protects articular cartilage in a surgical mouse model of osteoarthritis. SCIENTIFIC REPORTS, 10(1). doi:10.1038/s41598-020-66233-0
Low protein intake compromises the recovery of lactation-induced bone loss in female mouse dams without affecting skeletal muscles
Kanakis, I., Alameddine, M., Scalabrin, M., van ‘t Hof, R., Liloglou, T., Ozanne, S., . . . Vasilaki, A. (2020). Low protein intake compromises the recovery of lactation-induced bone loss in female mouse dams without affecting skeletal muscles. doi:10.1101/2020.05.02.073759
Post-traumatic osteoarthritis development is not modified by postnatal chondrocyte deletion of CCN2
2019
CHONDROCYTE SPECIFIC EXPRESSION OF CCN2 DOES NOT MODIFY OSTEOARTHRITIS DEVELOPMENT IN MICE
Keenan, C., Ramos, L., Kanakis, I., Milner, P., Abraham, D., Bou-Gharios, G., & Poulet, B. (2019). CHONDROCYTE SPECIFIC EXPRESSION OF CCN2 DOES NOT MODIFY OSTEOARTHRITIS DEVELOPMENT IN MICE. In OSTEOARTHRITIS AND CARTILAGE Vol. 27 (pp. S162). doi:10.1016/j.joca.2019.02.240
Targeted Inhibition of Aggrecanases Prevents Articular Cartilage Degradation and Augments Bone Mass in the STR/Ort Mouse Model of Spontaneous Osteoarthritis
Kanakis, I., Liu, K., Poulet, B., Javaheri, B., van 't Hof, R. J., Pitsillides, A. A., & Bou-Gharios, G. (2019). Targeted Inhibition of Aggrecanases Prevents Articular Cartilage Degradation and Augments Bone Mass in the STR/Ort Mouse Model of Spontaneous Osteoarthritis. Arthritis and Rheumatology, 71(4), 571-582. doi:10.1002/art.40765
2018
CCN2 DEFICIENCY IN CHONDROCYTES DOES NOT EXACERBATE OSTEOARTHRITIS IN TRAUMA-INDUCED MOUSE MODELS
Keenan, C., Milner, P., Kanakis, I., Carter, A., Abraham, D., Leask, A., . . . Poulet, B. (2018). CCN2 DEFICIENCY IN CHONDROCYTES DOES NOT EXACERBATE OSTEOARTHRITIS IN TRAUMA-INDUCED MOUSE MODELS. In OSTEOARTHRITIS AND CARTILAGE Vol. 26 (pp. S79). doi:10.1016/j.joca.2018.02.168
Maternal Protein Restriction Mediates the Development of the Musculoskeletal System in the Offspring
Vasilaki, A., Kanakis, I., Giakoumaki, I., Pollock, N., McArdle, A., Sayer, A. A., & Whysall, K. (2018). Maternal Protein Restriction Mediates the Development of the Musculoskeletal System in the Offspring. The FASEB Journal, 32(S1). doi:10.1096/fasebj.2018.32.1_supplement.907.6
The Chondro-Osseous Continuum: Is It Possible to Unlock the Potential Assigned Within?
Javaheri, B., Caetano-Silva, S. P., Kanakis, I., Bou-Gharios, G., & Pitsillides, A. A. (2018). The Chondro-Osseous Continuum: Is It Possible to Unlock the Potential Assigned Within?. Frontiers in Bioengineering and Biotechnology, 6. doi:10.3389/fbioe.2018.00028
Chondrocyte specific deletion of CCN2 does not exacerbate osteoarthritis in models of post-traumatic osteoarthritis in mice
Keenan, C., Jaffa, M., Milner, P., Kanakis, I., Carter, A., Abraham, D., . . . Poulet, B. (2018). Chondrocyte specific deletion of CCN2 does not exacerbate osteoarthritis in models of post-traumatic osteoarthritis in mice. In INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY Vol. 99 (pp. A14). Retrieved from https://www.webofscience.com/
Maternal Protein Restriction Mediates the Development of the Musculoskeletal System in the Offspring
Vasilaki, A., Kanakis, I., Giakoumaki, I., Pollock, N., McArdle, A., Sayer, A. A., & Whysall, K. (2018). Maternal Protein Restriction Mediates the Development of the Musculoskeletal System in the Offspring. In FASEB JOURNAL Vol. 32. Retrieved from https://www.webofscience.com/
The effect of [-1A]TIMP3 overexpression on bone mass in the naturally developing OA STR/Ort mice
Kanakis, I., van't Hof, R., Liu, K., Pitsillides, A., & Bou-Gharios, G. (2018). The effect of [-1A]TIMP3 overexpression on bone mass in the naturally developing OA STR/Ort mice. In INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY Vol. 99 (pp. A17-A18). Retrieved from https://www.webofscience.com/
2017
TSG-6 protects cartilage and bone by modulating the activities of chondrocytes and osteoclasts: a potential therapeutic for musculoskeletal disorders
Milner, C. M., Drummond, S. P., Kanakis, I., Scott, J. L., Hassall, G. A., Thomson, J. M., . . . Day, A. J. (2016). TSG-6 protects cartilage and bone by modulating the activities of chondrocytes and osteoclasts: a potential therapeutic for musculoskeletal disorders. In INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY Vol. 97 (pp. A26-A27). Retrieved from https://www.webofscience.com/
2016
CONNECTIVE TISSUE GROWTH FACTOR DEFICIENCY IN ADULT ARTICULAR CARTILAGE PROMOTES CARTILAGE DEGENERATION AT EARLY TIMEPOINTSIN MOUSE POSTTRAUMATIC OSTEOARTHRITIS
Poulet, B., Milner, P., Kanakis, I., Carter, A., Abraham, D., Leask, A., . . . Bou-Gharios, G. (2016). CONNECTIVE TISSUE GROWTH FACTOR DEFICIENCY IN ADULT ARTICULAR CARTILAGE PROMOTES CARTILAGE DEGENERATION AT EARLY TIMEPOINTSIN MOUSE POSTTRAUMATIC OSTEOARTHRITIS. In OSTEOARTHRITIS AND CARTILAGE Vol. 24 (pp. S392). doi:10.1016/j.joca.2016.01.705
2015
PRECLINICAL EVALUATION OF THE LINK MODULE FROM THE HUMAN TSG-6 PROTEIN: A POTENTIAL NEW THERAPEUTIC FOR BONE LOSS AND CARTILAGE DAMAGE IN MUSCULOSKELETAL DISORDERS
Kanakis, I., Scott, J. L., Drummond, S. P., Hassall, G. A., Thomson, J. M., Hardman, M. J., . . . Milner, C. M. (2015). PRECLINICAL EVALUATION OF THE LINK MODULE FROM THE HUMAN TSG-6 PROTEIN: A POTENTIAL NEW THERAPEUTIC FOR BONE LOSS AND CARTILAGE DAMAGE IN MUSCULOSKELETAL DISORDERS. In OSTEOPOROSIS INTERNATIONAL Vol. 26 (pp. S360). Retrieved from https://www.webofscience.com/
2014
Preclinical evaluation of the link module from human TSG--6 as a novel anti-resorptive agent for postmenopausal osteoporosis
Kanakis, I., Scott, J., Thomson, J., Hassall, G., Hardman, M., Milner, C., & Day, A. (n.d.). Preclinical evaluation of the link module from human TSG--6 as a novel anti-resorptive agent for postmenopausal osteoporosis. Bone Abstracts. doi:10.1530/boneabs.3.pp313
PRE-CLINICAL EVALUATION OF THE LINK MODULE DOMAIN FROM THE HUMAN PROTEIN TSG-6: A NOVEL ANTI-RESORPTIVE AGENT
Milner, C. M., Scott, J. L., Kanakis, I., Thomson, J. M., Hassall, G. A., Hardman, M. J., & Day, A. J. (2014). PRE-CLINICAL EVALUATION OF THE LINK MODULE DOMAIN FROM THE HUMAN PROTEIN TSG-6: A NOVEL ANTI-RESORPTIVE AGENT. In OSTEOPOROSIS INTERNATIONAL Vol. 25 (pp. S667). Retrieved from https://www.webofscience.com/
2013
Preclinical evaluation of zoledronate using an in vitro mimetic cellular model for breast cancer metastatic bone disease
Dedes, P. G., Kanakis, I., Gialeli, C., Theocharis, A. D., Tsegenidis, T., Kletsas, D., . . . Karamanos, N. K. (2013). Preclinical evaluation of zoledronate using an in vitro mimetic cellular model for breast cancer metastatic bone disease. BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS, 1830(6), 3625-3634. doi:10.1016/j.bbagen.2013.01.020
2012
Expression of matrix macromolecules and functional properties of breast cancer cells are modulated by the bisphosphonate zoledronic acid
Dedes, P. G., Gialeli, C., Tsonis, A. I., Kanakis, I., Theocharis, A. D., Kletsas, D., . . . Karamanos, N. K. (2012). Expression of matrix macromolecules and functional properties of breast cancer cells are modulated by the bisphosphonate zoledronic acid. BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS, 1820(12), 1926-1939. doi:10.1016/j.bbagen.2012.07.013
Glycosaminoglycans as Key Molecules in Atherosclerosis: The Role of Versican and Hyaluronan
Karangelis, D. E., Kanakis, I., Asimakopoulou, A. P., Karousou, E., Passi, A., Theocharis, A. D., . . . Karamanos, N. K. (2010). Glycosaminoglycans as Key Molecules in Atherosclerosis: The Role of Versican and Hyaluronan. CURRENT MEDICINAL CHEMISTRY, 17(33), 4018-4026. Retrieved from https://www.webofscience.com/
2011
Heparan sulfate: biological significance, tools for biochemical analysis and structural characterization
Malavaki, C. J., Theocharis, A. D., Lamari, F. N., Kanakis, I., Tsegenidis, T., Tzanakakis, G. N., & Karamanos, N. K. (2011). Heparan sulfate: biological significance, tools for biochemical analysis and structural characterization. BIOMEDICAL CHROMATOGRAPHY, 25(1-2), 11-20. doi:10.1002/bmc.1536
Monitoring serum chondroitin sulfate levels in patients submitted to coronary artery bypass surgery
Karangelis, D., Asimakopoulou, A., Kanakis, I., Tagarakis, G. I., Koufakis, T., Triposkiadis, F., . . . Karamanos, N. K. (2011). Monitoring serum chondroitin sulfate levels in patients submitted to coronary artery bypass surgery. BIOMEDICAL CHROMATOGRAPHY, 25(7), 748-750. doi:10.1002/bmc.1533
2009
A Comparative Biochemical Analysis of Glycosaminoglycans and Proteoglycans in Human Orthotopic and Heterotopic Bone
Mania, V. M., Kallivokas, A. G., Malavaki, C., Asimakopoulou, A. P., Kanakis, J., Theocharis, A. D., . . . Karamanos, N. K. (2009). A Comparative Biochemical Analysis of Glycosaminoglycans and Proteoglycans in Human Orthotopic and Heterotopic Bone. IUBMB LIFE, 61(4), 447-452. doi:10.1002/iub.167
The impact of zoledronic acid therapy in survival of lung cancer patients with bone metastasis
Zarogoulidis, K., Boutsikou, E., Zarogoulidis, P., Eleftheriadou, E., Kontakiotis, T., Lithoxopoulou, H., . . . Karamanos, N. K. (2009). The impact of zoledronic acid therapy in survival of lung cancer patients with bone metastasis. INTERNATIONAL JOURNAL OF CANCER, 125(7), 1705-1709. doi:10.1002/ijc.24470
2008
Comparison of bead-based bioassay and enzyme-linked immunoassay for the determination of osteocalsin in biological samples
Malavaki, C. J., Kanakis, I., & Karamanos, N. K. (2008). Comparison of bead-based bioassay and enzyme-linked immunoassay for the determination of osteocalsin in biological samples. In FEBS JOURNAL Vol. 275 (pp. 457). Retrieved from https://www.webofscience.com/
Involvement of circulating hyaluronic acid in osteoclastic bone resorption of breast cancer metastatic bone disease
Kanakis, I., Dedes, P., Nikolaou, M., Pectasides, D., & Karamanos, N. (2008). Involvement of circulating hyaluronic acid in osteoclastic bone resorption of breast cancer metastatic bone disease. In FEBS JOURNAL Vol. 275 (pp. 243). Retrieved from https://www.webofscience.com/
Zoledronate as a potent inhibitor of the expression of syndecan-1, glypican-1 and proliferation of breast cancer cells
Dedes, P., Kousidou, O., Kanakis, I., Gialeli, C., & Karamanos, N. (2008). Zoledronate as a potent inhibitor of the expression of syndecan-1, glypican-1 and proliferation of breast cancer cells. In FEBS JOURNAL Vol. 275 (pp. 243). Retrieved from https://www.webofscience.com/
2007
Imatinib inhibits colorectal cancer cell growth and suppresses stromal-induced growth stimulation, MT1-MMP expression and pro-M-MP2 activation
Stahtea, X. N., Roussidis, A. E., Kanakis, I., Tzanakakis, G. N., Chalkiadakis, G., Mavroudis, D., . . . Karamanos, N. K. (2007). Imatinib inhibits colorectal cancer cell growth and suppresses stromal-induced growth stimulation, MT1-MMP expression and pro-M-MP2 activation. INTERNATIONAL JOURNAL OF CANCER, 121(12), 2808-2814. doi:10.1002/ijc.23029
Hyaluronan determination: Biological significance & analytical tools
Malavaki, C. J., Kanakis, I., Theocharis, A. D., Lamari, F. N., & Karamanos, N. K. (2007). Hyaluronan determination: Biological significance & analytical tools. CURRENT PHARMACEUTICAL ANALYSIS, 3(2), 117-128. doi:10.2174/157341207780598940
Expression and distribution of <i>N</i>-acetyl and <i>N</i>-glycolylneuraminic acids in secreted and cell-associated glycoconjugates by two human osteosarcoma cell lines
Tzanakakis, G. N., Nikitovic, D., Katonis, P., Kanakis, I., & Karamanos, N. K. (2007). Expression and distribution of <i>N</i>-acetyl and <i>N</i>-glycolylneuraminic acids in secreted and cell-associated glycoconjugates by two human osteosarcoma cell lines. BIOMEDICAL CHROMATOGRAPHY, 21(4), 406-409. doi:10.1002/bmc.771
c-kit as potential target in autocrine/paracrine controled expression of metalloproteases and cell growth in colon cancer
Staxtea, X., Roussidis, A., Kanakis, I., Tzanakakis, G., Chalkiadakis, G., Mavroudis, D., . . . Karamanos, N. (2007). c-kit as potential target in autocrine/paracrine controled expression of metalloproteases and cell growth in colon cancer. In FEBS JOURNAL Vol. 274 (pp. 185). Retrieved from https://www.webofscience.com/
2006
Serglycin constitutively secreted by myeloma plasma cells is a potent inhibitor of bone mineralization <i>in vitro</i>
Theocharis, A. D., Seidel, C., Borset, M., Dobra, K., Baykov, V., Labropoulou, V., . . . Hjerpe, A. (2006). Serglycin constitutively secreted by myeloma plasma cells is a potent inhibitor of bone mineralization <i>in vitro</i>. JOURNAL OF BIOLOGICAL CHEMISTRY, 281(46), 35116-35128. doi:10.1074/jbc.M601061200
Signaling pathways in cancer-induced bone disease and the inhibitory effect of bisphosphonates
Kanakis, I., Stahtea, X., Dedes, P. G., & Karamanos, N. K. (2006). Signaling pathways in cancer-induced bone disease and the inhibitory effect of bisphosphonates. In Review of Clinical Pharmacology and Pharmacokinetics, International Edition Vol. 20 (pp. 189-191).
Crystallization of hydroxyapatite on oxadiazole-based homopolymers
Kanakis, J., Chrissanthopoulos, A., Tzanetos, N. P., Kallitsis, J. K., & Dalas, E. (2006). Crystallization of hydroxyapatite on oxadiazole-based homopolymers. CRYSTAL GROWTH & DESIGN, 6(6), 1547-1552. doi:10.1021/cg060015u
Determination and distribution of <i>N</i>-acetyl- and <i>N</i>-glycolylneuraminic acids in culture media and cell-associated glycoconjugates from human malignant mesothelioma and adenocarcinoma cells
Tzanakakis, G. N., Syrokou, A., Kanakis, I., & Karamanos, N. K. (2006). Determination and distribution of <i>N</i>-acetyl- and <i>N</i>-glycolylneuraminic acids in culture media and cell-associated glycoconjugates from human malignant mesothelioma and adenocarcinoma cells. BIOMEDICAL CHROMATOGRAPHY, 20(5), 434-439. doi:10.1002/bmc.573
Determination of ascorbic acid, uric acid and malondialdehyde in reflex tears of diabetic children with capillary electrophoresis
Eliopoulou, M., Spiliotis, B., Georgakopoulos, C., Exarchou, A., Lamari, F., Kanakis, J., & Karamanos, N. (2006). Determination of ascorbic acid, uric acid and malondialdehyde in reflex tears of diabetic children with capillary electrophoresis. In HORMONE RESEARCH Vol. 65 (pp. 52-53). Retrieved from https://www.webofscience.com/
Identification of the commonest cystic fibrosis transmembrane regulator gene ΔF508 mutation:: evaluation of PCR-single-strand conformational polymorphism and polyacrylamide gel electrophoresis
Kakavas, K. V., Noulas, A. V., Kanakis, I., Bonanou, S., & Karamanos, N. K. (2006). Identification of the commonest cystic fibrosis transmembrane regulator gene ΔF508 mutation:: evaluation of PCR-single-strand conformational polymorphism and polyacrylamide gel electrophoresis. BIOMEDICAL CHROMATOGRAPHY, 20(10), 1120-1125. doi:10.1002/bmc.657
Molecular approach on breast cancer cell biology and bone metastasis
Karamanos, N., Kanakis, I., Roussidis, A., Kousidou, O., & Theocharis, A. (2006). Molecular approach on breast cancer cell biology and bone metastasis. In FEBS JOURNAL Vol. 273 (pp. 103). Retrieved from https://www.webofscience.com/
2005
State of the art of biochemical markers in metastatic bone disease and the role of bisphosphonates as therapeutic agents
Kanakis, I., Theocharis, A. D., Noulas, A. V., & Karamanos, N. K. (2005). State of the art of biochemical markers in metastatic bone disease and the role of bisphosphonates as therapeutic agents. CURRENT PHARMACEUTICAL ANALYSIS, 1(3), 225-241. doi:10.2174/157341205774597850
Clinical value of bone remodelling markers in patients with bone metastases treated with zoledronic acid.
Pectasides, D., Nikolaou, M., Farmakis, D., Kanakis, I., Gaglia, A., Kountourakis, P., . . . Raptis, S. A. (2005). Clinical value of bone remodelling markers in patients with bone metastases treated with zoledronic acid.. Anticancer research, 25(2B), 1457-1463.
Diagnostic value of bone remodeling markers in the diagnosis of bone metastases in patients with breast cancer
Pectasides, D., Farmakis, D., Nikolaou, M., Kanakis, I., Kostopoulou, V., Papaconstantinou, I., . . . Raptis, S. A. (2005). Diagnostic value of bone remodeling markers in the diagnosis of bone metastases in patients with breast cancer. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 37(1), 171-176. doi:10.1016/j.jpba.2004.10.007
<i>In vitro</i> and <i>in vivo</i> antiresorptive effects of bisphosphonates in metastatic bone disease
Kanakis, I., Kousidou, O. C., & Karamanos, N. K. (2005). <i>In vitro</i> and <i>in vivo</i> antiresorptive effects of bisphosphonates in metastatic bone disease. IN VIVO, 19(1), 311-318. Retrieved from https://www.webofscience.com/
Clinical value of bone remodelling markers in patients with bone metastases treated with zoledronic acid
Pectasides, D., Nikolaou, M., Farmakis, D., Kanakis, I., Gaglia, A., Kountourakis, P., . . . Raptis, S. A. (2005). Clinical value of bone remodelling markers in patients with bone metastases treated with zoledronic acid. ANTICANCER RESEARCH, 25(2B), 1457-1463. Retrieved from https://www.webofscience.com/
Effects of zoledronic acid on serum levels of MMPs and bone remodeling markers in breast cancer patients with bone metastases
Kanakis, I., Nikolaou, M., Kiamouris, C., Pectasides, D., & Karamanos, N. (2005). Effects of zoledronic acid on serum levels of MMPs and bone remodeling markers in breast cancer patients with bone metastases. In FEBS JOURNAL Vol. 272 (pp. 270). Retrieved from https://www.webofscience.com/
2004
The effect of leucine on the crystal growth of calcium carbonate
Malkaj, P., Kanakis, J., & Dalas, E. (2004). The effect of leucine on the crystal growth of calcium carbonate. JOURNAL OF CRYSTAL GROWTH, 266(4), 533-538. doi:10.1016/j.jcrysgro.2004.02.114
Determination and biological relevance of serum cross-linked type I collagen <i>N</i>-telopeptide and bone-specific alkaline phosphatase in breast metastatic cancer
Kanakis, I., Nikolaou, M., Pectasides, D., Kiamouris, C., & Karamanos, N. K. (2004). Determination and biological relevance of serum cross-linked type I collagen <i>N</i>-telopeptide and bone-specific alkaline phosphatase in breast metastatic cancer. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 34(4), 827-832. doi:10.1016/S0731-7085(03)00567-3
SERUM LEVELS OF MMP-2, BAP and NTx IN BREAST CANCER PATIENTS WITH SKELETAL METASTASES TREATED WITH ZOLEDRONIC ACID
Kanakis, I. G., Nikolaou, M., Pectasides, D., Kiamouris, C., & Karamanos, N. K. (2004). SERUM LEVELS OF MMP-2, BAP and NTx IN BREAST CANCER PATIENTS WITH SKELETAL METASTASES TREATED WITH ZOLEDRONIC ACID. In ANTICANCER RESEARCH Vol. 24 (pp. 3530). Retrieved from https://www.webofscience.com/
2003
Capillary electrophoresis and enzyme solid phase assay for examining the purity of a synthetic heparin proteoglycan-like conjugate and identifying binding to basic fibroblast growth factor
Dimitrellos, V., Lamari, F. N., Militsopoulou, M., Kanakis, I., & Karamanos, N. K. (2003). Capillary electrophoresis and enzyme solid phase assay for examining the purity of a synthetic heparin proteoglycan-like conjugate and identifying binding to basic fibroblast growth factor. BIOMEDICAL CHROMATOGRAPHY, 17(1), 42-47. doi:10.1002/bmc.208
Screening of cerebrospinal fluid and blood sera of multiple sclerosis patients for oligoclonal immunoglobulins by capillary electrophoresis
Kanakis, I., Stavropoulou, C., Lamari, F. N., Heliopoulos, Y., Iordanidou, H., Piperidou, H., . . . Karamanos, N. K. (2003). Screening of cerebrospinal fluid and blood sera of multiple sclerosis patients for oligoclonal immunoglobulins by capillary electrophoresis. In CHROMATOGRAPHIA Vol. 58 (pp. 513-516). doi:10.1365/s10337-003-0070-2
2002
The effect of aminoacids on the crystal growth of calcium carbonate
Manoli, F., Kanakis, J., Malkaj, P., & Dalas, E. (2002). The effect of aminoacids on the crystal growth of calcium carbonate. JOURNAL OF CRYSTAL GROWTH, 236(1-3), 363-370. doi:10.1016/S0022-0248(01)02164-9
2001
The crystallization of calcium carbonate on porcine and human cardiac valves and the antimineralization effect of sodium alginate
Kanakis, J., Malkaj, P., Petroheilos, J., & Dalas, E. (2001). The crystallization of calcium carbonate on porcine and human cardiac valves and the antimineralization effect of sodium alginate. JOURNAL OF CRYSTAL GROWTH, 223(4), 557-564. doi:10.1016/S0022-0248(01)00698-4
2000
The crystallization of vaterite on fibrin
Kanakis, J., & Dalas, E. (2000). The crystallization of vaterite on fibrin. JOURNAL OF CRYSTAL GROWTH, 219(3), 277-282. doi:10.1016/S0022-0248(00)00623-0