Research
Research groups
- Medical Statistics
- International Health
Research grants
Pilot-Education and training for recruiters to randomised trials
HEALTH RESEARCH BOARD (IRELAND)
January 2018 - December 2021
Extending ORRCA to create a central resource for retention research within clinical trials (ORRCA 2)
MEDICAL RESEARCH COUNCIL
June 2018 - November 2019
The Carboprost or Oxytocin Postpartum haemorrhage Effectiveness Study (COPE)
DEPARTMENT OF HEALTH & SOCIAL CARE (UK)
September 2017 - November 2025
MIROR Methods in research on research
EUROPEAN COMMISSION
March 2016 - February 2020
From evidence to guidance on patient recruitment to clinical research in intensive care units.
ECONOMIC AND SOCIAL RESEARCH COUNCIL
September 2016 - May 2020
Methods for Patient and Public Involvement in Clinical Trials: A Research Priority and Agenda Setting Exercise.
MEDICAL RESEARCH COUNCIL
October 2015 - May 2017
TOPS: Timing of Primary Surgery for Cleft Palate (renewal)
NATIONAL INSTITUTES OF HEALTH (USA)
July 2016 - June 2021
The TRECA study: TRials Engagement in Children and Adolescents
DEPARTMENT OF HEALTH & SOCIAL CARE (UK)
February 2016 - July 2020
How does treatment with thyroxine for 6 weeks postnatally given to preterm infants born under 28 weeks gestation affect the hypothalamic-pituitary adrenal axix, somatic growth, meylination of white matter and the volumes of key brain structures? An exploratory randomised double blinded placebo controlled clinical trial
MEDICAL RESEARCH COUNCIL
March 2007 - May 2010
Development of an interactive website for outcome reporting bias research
MEDICAL RESEARCH COUNCIL
July 2015 - June 2016
Radiation versus observation following surgical resection of Atypical Meningioma: a randomised controlled trial (ROAM)
DEPARTMENT OF HEALTH & SOCIAL CARE (UK)
November 2014 - March 2026
ORBIT II: Outcome Reporting Bias In Trials
MEDICAL RESEARCH COUNCIL
June 2012 - December 2013
SLEEPS: Safety profiLe, Efficacy and Equivalence in Paediatric intensive care Sedation: A Comparison of Clonidine and Midazolam
DEPARTMENT OF HEALTH & SOCIAL CARE (UK)
July 2007 - November 2012
Understanding the process and impact of within-study selective reporting bias.
MEDICAL RESEARCH COUNCIL
October 2006 - November 2008
Duration of intravenous antibiotic therapy for children with acute osteomyelitis or septic arthritis: a feasibility study
DEPARTMENT OF HEALTH & SOCIAL CARE (UK)
October 2012 - May 2015
Evaluation of Corticosteroid therapy in Childhood Severe Sepsis- a randomised pilot study
MENINGITIS RESEARCH FOUNDATION (UK)
October 2013 - June 2014
North West Hub for Trial Methodology Research (NWHTMR)
MEDICAL RESEARCH COUNCIL
October 2008 - August 2014
PREVAIL-Preventing infection using antibiotic impregnated long lines
DEPARTMENT OF HEALTH & SOCIAL CARE (UK), UNIVERSITY COLLEGE LONDON (UK)
June 2014 - August 2019
StePS study
MENINGITIS RESEARCH FOUNDATION (UK)
October 2007 - April 2013
A pragmatic randomised controlled trial of intravenous levetiracetam versus intravenous phenytoin in terminating acute, prolonged tonic-clonic seizures including convulsive status epilepticus in children, the 'EcLIPSE' Study: Emergency treatment with Levetiracetam or Phenytoin in Status Epilepticus
DEPARTMENT OF HEALTH & SOCIAL CARE (UK)
June 2014 - July 2019
Losing the losses: understanding the reasons for attrition in randomised trials and developing the evidence to prevent it
MEDICAL RESEARCH COUNCIL
October 2013 - July 2015
Onabotulinium toxin-A versus extended release tolterodine in the management of idiopathic overactive bladder in children: A pilot randomised controlled trial OVERT
DEPARTMENT OF HEALTH & SOCIAL CARE (UK)
July 2014 - August 2018
Healing Foundation Clinical Trials Unit
THE SCAR FREE FOUNDATION
June 2011 - September 2020
Establishing a database of statistical expertise to support clinical trial oversight committees and develop capacity
MEDICAL RESEARCH COUNCIL
April 2014 - September 2015
TP 165 feasilbility study of enhanced relapse prevention by key workers for people diagnosed with Bipolar Disorder.
MEDICAL RESEARCH COUNCIL
January 2005 - January 2007
The British Antibiotic and Silver Impregnated Catheters for ventriculoperitoneal Shunts multi-centre randomised controlled trial (The BASICS trial)
DEPARTMENT OF HEALTH & SOCIAL CARE (UK)
June 2012 - February 2019
Training key workers to offer enhanced relapse prevention to people with bipolar disorder and their relatives within an NHS setting.
MERSEY CARE NHS FOUNDATION TRUST (UK)
September 2004 - August 2007
Trial steering committees for randomised controlled trials: Updating and redeveloping guidance and terms of reference, informed by current practice and experience
MEDICAL RESEARCH COUNCIL
October 2012 - September 2014
Clinical trial monitoring: establishing best UK practice?
MEDICAL RESEARCH COUNCIL
September 2011 - May 2013
MOMENT The management of otitis media with effusion (OME) in children with cleft palate
CENTRAL MANCHESTER TEACHING HOSPITALS (UK)
August 2012 - August 2013
Development of guidance for statistical analysis plans for clinical trials
MEDICAL RESEARCH COUNCIL
April 2014 - December 2016
Consolidating guidelines for the prevention, detection and appraisal of reporting biases in clinical trials
MEDICAL RESEARCH COUNCIL
May 2012 - October 2013
Medicines for Children Research Network Clinical Trials Unit
DEPARTMENT OF HEALTH & SOCIAL CARE (UK)
April 2010 - March 2015
Development of a central resource for research in recruitment in clinical trials
MEDICAL RESEARCH COUNCIL
March 2014 - November 2018
Use of the electronic health record in the design and conduct of clinical trials
MEDICAL RESEARCH COUNCIL
November 2013 - September 2016
Innovative Mental Health Clinical Trials Methodology Hub
MEDICAL RESEARCH COUNCIL
June 2024 - March 2025
The clinical and cost effectiveness of quetiapine for people with borderline personality disorder: A pragmatic, double-blind, placebo-controlled, randomised trial. (QUEST)
DEPARTMENT OF HEALTH & SOCIAL CARE (UK)
June 2024 - October 2028
A modular, multi-arm, first in human trial to evaluate the safety and tolerability of MDX-124 alone and in combination with anti-cancer treatments, in subjects with locally advanced, unresectable or metastatic solid malignancies
MEDANNEX LIMITED (UK)
June 2022 - April 2027
Liverpool ECMC (LECMC)
CANCER RESEARCH UK (UK), DEPARTMENT OF HEALTH & SOCIAL CARE (UK)
April 2023 - March 2028
Vagus Nerve Stimulation for epilepsy in children and adults: Assessment of Longer term clinical and cost Effectiveness in a Randomised controlled Trial (VNS-ALERT) (VNS-ALERT)
DEPARTMENT OF HEALTH & SOCIAL CARE (UK)
June 2025 - May 2032
Development of resources to promote best practice for the Analysis of Harm outcomes in RCT's (DoRAH)
DEPARTMENT OF HEALTH & SOCIAL CARE (UK)
October 2022 - October 2023
A randomised trial of aminophylline, magnesium sulfate or salbutamol intravenous therapy for acute severe asthma in children and young people (EVITA)
DEPARTMENT OF HEALTH & SOCIAL CARE (UK)
January 2025 - December 2027
Devising a personalized risk stratification and holistic management for prevention of cognitive impairment in patients with different cardiovascular phenotypes
EUROPEAN COMMISSION
January 2025 - December 2029
Targeting non-small cell lung cancer with personalised doggybone DNA vaccines (db-PCV) (NEOVACC)
MEDICAL RESEARCH COUNCIL
December 2023 - November 2027
Changing clinical practice in rare diseases through innovative trial designs (CAPTIVATE)
MEDICAL RESEARCH COUNCIL
July 2023 - June 2028
Research Capability Funding for Statistical Support
ROYAL LIVERPOOL AND BROADGREEN UNIVERSITY HOSPITALS NHS TRUST (UK)
April 2017 - March 2023
GOTHIC2: A multi-centre randomised placebo-controlled trial of glycopyrrolate and hyoscine hydrobromide for the treatment of clozapine-induced hypersalivation. (GOTHIC 2)
DEPARTMENT OF HEALTH & SOCIAL CARE (UK)
November 2022 - November 2027
Three Pillars Study: The cyclin-dependent kinase 4/6 inhibitor palbociclib in combination with letrozole, trastuzumab plus tucatinib as neoadjvuant treatment for ER-positive, HER2-positive early breast cancer
SEAGEN INC (USA)
August 2022 - August 2027
RAPTOR:
DEPARTMENT OF HEALTH & SOCIAL CARE (UK)
October 2021 - April 2028
HElping Alleviate the Longer-term consequences of COVID-19 (HEAL-COVID): A national platform trial (HEAL-COVID)
DEPARTMENT OF HEALTH & SOCIAL CARE (UK), UNIVERSITY OF CAMBRIDGE (UK)
January 2021 - January 2029
Cardiac rehabilitation for people with chronic stable angina: a randomised controlled trial. Angina Controlled Trial Investigating the Value of the "Activate your heart" Therapeutic E-intervention (ACTIVATE)
DEPARTMENT OF HEALTH & SOCIAL CARE (UK)
August 2021 - June 2026
Academia and Industry United Innovation and Treatment for Tuberculosis ( UNITE4TB)
EUROPEAN COMMISSION
June 2021 - May 2028
Steroid TreAtment TRial in JIA: a randomised trial to compare effectiveness, safety and cost-effectiveness of oral versus intravenous corticosteroid induction regimens for children and young people with juvenile idiopathic arthritis (STAR-JIA)
DEPARTMENT OF HEALTH & SOCIAL CARE (UK)
January 2023 - July 2028
NIHR Senior Investigator Award Renewal
DEPARTMENT OF HEALTH & SOCIAL CARE (UK)
April 2021 - March 2029
An International World Health Organisation Collaboration to Implement and Evaluate at Scale the Active Prevention and Treatment of Maternal Sepsis (APT-Sepsis)
MEDICAL RESEARCH COUNCIL
February 2021 - April 2026
Research collaborations
Health Research Board Trials Methodology Research Network in Ireland
Health Research Board Trials Methodology Research Network in Ireland, www.hrb-tmrn.ie – adding value to areas of common scientific interest and training;
MRC Trials Methodology Research Partnership (TMRP)
The TMRP brings together a number of networks, institutions and partners working in trials and trials methodology research.The TMRP builds on the achievements of the MRC Hubs for Trials Methodology Research Network to make continued progress in advancing trial methodology, developing capacity and further reducing research waste. https://www.methodologyhubs.mrc.ac.uk/about/tmrp/