Publications
2021
Genomic profiling using the UltraSEEK panel identifies discordancy between paired primary and breast cancer brain metastases and an association with brain metastasis-free survival
Giannoudis, A., Sartori, A., Eastoe, L., Zakaria, R., Charlton, C., Hickson, N., . . . Palmieri, C. (2021). Genomic profiling using the UltraSEEK panel identifies discordancy between paired primary and breast cancer brain metastases and an association with brain metastasis-free survival. BREAST CANCER RESEARCH AND TREATMENT, 190(2), 241-253. doi:10.1007/s10549-021-06364-8
2020
Inactivated Fatty Acid-Binding Protein 5 (FABP5) is a Suppressor for Prostate Cancer
Al-Jameel, W., He, G., Jin, X., Zhang, J., Al-Bayati, A., Platt-Higgins, A., . . . Ke, Y. (2020). Inactivated Fatty Acid-Binding Protein 5 (FABP5) is a Suppressor for Prostate Cancer. In Prime Archives in Genetics. Vide Leaf, Hyderabad. doi:10.37247/pag.1.2020.8
2019
A novel panel of differentially-expressed microRNAs in breast cancer brain metastasis may predict patient survival
Giannoudis, A., Clarke, K., Zakaria, R., Vareslija, D., Farahani, M., Rainbow, L., . . . Palmieri, C. (2019). A novel panel of differentially-expressed microRNAs in breast cancer brain metastasis may predict patient survival. SCIENTIFIC REPORTS, 9. doi:10.1038/s41598-019-55084-z
Inactivated FABP5 suppresses malignant progression of prostate cancer cells by inhibiting the activation of nuclear fatty acid receptor PPARγ
Al-Jameel, W., Gou, X., Jin, X., Zhang, J., Wei, Q., Ai, J., . . . Ke, Y. (2019). Inactivated FABP5 suppresses malignant progression of prostate cancer cells by inhibiting the activation of nuclear fatty acid receptor PPARγ. Genes and Cancer, 10(3-4), 80-96. doi:10.18632/genesandcancer.192
2018
T-Cell Densities in Brain Metastases Are Associated with Patient Survival Times and Diffusion Tensor MRI Changes
Zakaria, R., Platt-Higgins, A., Rathi, N., Radon, M., Das, S., Das, K., . . . Rudland, P. S. (2018). T-Cell Densities in Brain Metastases Are Associated with Patient Survival Times and Diffusion Tensor MRI Changes. CANCER RESEARCH, 78(3), 610-616. doi:10.1158/0008-5472.CAN-17-1720
2017
Erythropoietin drives breast cancer progression by activation of its receptor EPOR
Chan, K. K., Matchett, K. B., Coulter, J. A., Yuen, H. -F., McCrudden, C. M., Zhang, S. -D., . . . Lappin, T. R. (2017). Erythropoietin drives breast cancer progression by activation of its receptor EPOR. ONCOTARGET, 8(24), 38251-38263. doi:10.18632/oncotarget.16368
2016
Ran GTPase promotes cancer progression via Met receptor-mediated downstream signaling
Yuen, H. -F., Chan, K. -K., Platt-Higgins, A., Dakir, E. -H., Matchett, K. B., Haggag, Y. A., . . . El-Tanani, M. (2016). Ran GTPase promotes cancer progression via Met receptor-mediated downstream signaling. ONCOTARGET, 7(46), 75854-75864. doi:10.18632/oncotarget.12420
S100A4 Elevation Empowers Expression of Metastasis Effector Molecules in Human Breast Cancer.
Ismail, T. M., Bennett, D., Platt-Higgins, A. M., Al-Medhity, M., Barraclough, R., & Rudland, P. S. (2016). S100A4 Elevation Empowers Expression of Metastasis Effector Molecules in Human Breast Cancer.. Cancer research, 77(3), 780-789. doi:10.1158/0008-5472.can-16-1802
Metastasis-inducing proteins are widely expressed in human brain metastases and associated with intracranial progression and radiation response
Zakaria, R., Platt-Higgins, A., Rathi, N., Crooks, D., Brodbelt, A., Chavredakis, E., . . . Rudland, P. S. (2016). Metastasis-inducing proteins are widely expressed in human brain metastases and associated with intracranial progression and radiation response. British Journal of Cancer, 114(10), 1101-1108. doi:10.1038/bjc.2016.103
2013
RanGTPase: a candidate for Myc-mediated cancer progression.
Yuen, H. -F., Gunasekharan, V. -K., Chan, K. -K., Zhang, S. -D., Platt-Higgins, A., Gately, K., . . . El-Tanani, M. (2013). RanGTPase: a candidate for Myc-mediated cancer progression.. Journal of the National Cancer Institute, 105(7), 475-488. doi:10.1093/jnci/djt028
2012
Aberrant expression of metastasis-inducing proteins in ectopic and matched eutopic endometrium of women with endometriosis: implications for the pathogenesis of endometriosis
Hapangama, D. K., Raju, R. S., Valentijn, A. J., Barraclough, D., Hart, A., Turner, M. A., . . . Rudland, P. S. (2012). Aberrant expression of metastasis-inducing proteins in ectopic and matched eutopic endometrium of women with endometriosis: implications for the pathogenesis of endometriosis. HUMAN REPRODUCTION, 27(2), 394-407. doi:10.1093/humrep/der412
Ran is a potential therapeutic target for cancer cells with molecular changes associated with activation of the PI3K/Akt/mTORC1 and Ras/MEK/ERK pathways.
Yuen, H. -F., Chan, K. -K., Grills, C., Murray, J. T., Platt-Higgins, A., Eldin, O. S., . . . El-Tanani, M. (2012). Ran is a potential therapeutic target for cancer cells with molecular changes associated with activation of the PI3K/Akt/mTORC1 and Ras/MEK/ERK pathways.. Clinical cancer research : an official journal of the American Association for Cancer Research, 18(2), 380-391. doi:10.1158/1078-0432.ccr-11-2035
2011
Statistical Association of Basal Cell Keratins with Metastasis-Inducing Proteins in a Prognostically Unfavorable Group of Sporadic Breast Cancers
Rudland, S. D. S., Platt-Higgins, A., Winstanley, J. H. R., Jones, N. J., Barraclough, R., West, C., . . . Rudland, P. S. (2011). Statistical Association of Basal Cell Keratins with Metastasis-Inducing Proteins in a Prognostically Unfavorable Group of Sporadic Breast Cancers. AMERICAN JOURNAL OF PATHOLOGY, 179(2), 1061-1072. doi:10.1016/j.ajpath.2011.04.022
2010
Osteopontin can act as an effector for a germline mutation of BRCA1 in malignant transformation of breast cancer-related cells.
El-Tanani, M. K., Yuen, H. -F., Shi, Z., Platt-Higgins, A., Buckley, N. E., Mullan, P. B., . . . Rudland, P. S. (2010). Osteopontin can act as an effector for a germline mutation of BRCA1 in malignant transformation of breast cancer-related cells.. Cancer science, 101(6), 1354-1360. doi:10.1111/j.1349-7006.2010.01561.x
Significance of the Fanconi Anemia FANCD2 Protein in Sporadic and Metastatic Human Breast Cancer
Rudland, P. S., Platt-Higgins, A. M., Davies, L. M., Rudland, S. D. S., Wilson, J. B., Aladwani, A., . . . Jones, N. J. (2010). Significance of the Fanconi Anemia FANCD2 Protein in Sporadic and Metastatic Human Breast Cancer. AMERICAN JOURNAL OF PATHOLOGY, 176(6), 2935-2947. doi:10.2353/ajpath.2010.090779
2009
The Metastasis-Associated Anterior Gradient 2 Protein Is Correlated with Poor Survival of Breast Cancer Patients
Barraclough, D. L., Platt-Higgins, A., Rudland, S. D. S., Barraclough, R., Winstanley, J., West, C. R., & Rudland, P. S. (2009). The Metastasis-Associated Anterior Gradient 2 Protein Is Correlated with Poor Survival of Breast Cancer Patients. AMERICAN JOURNAL OF PATHOLOGY, 175(5), 1848-1857. doi:10.2353/ajpath.2009.090246
2007
'A novel monoclonal antibody against human S100A4: Its production, characterization and application'
Zhang, N., Dumin, M., Platt-Higgins, A., Hu, X. Y., Ye, Y. Y., He, D. W., . . . Huang, X. M. (2007). 'A novel monoclonal antibody against human S100A4: Its production, characterization and application'. Calcium Binding Proteins, 1(4), 219-223.
2006
Significance of the metastasis-inducing protein AGR2 for outcome in hormonally treated breast cancer patients
Innes, H. E., Liu, D., Barraclough, R., Davies, M. P. A., O'Neill, P. A., Platt-Higgins, A., . . . Rudland, P. S. (2006). Significance of the metastasis-inducing protein AGR2 for outcome in hormonally treated breast cancer patients. BRITISH JOURNAL OF CANCER, 94(7), 1057-1065. doi:10.1038/sj.bjc.6603065
Association of S100A4 and osteopontin with specific prognostic factors and survival of patients with minimally invasive breast cancer
Rudland, S. D. S., Martin, L., Roshanlall, C., Winstanley, J., Leinster, S., Platt-Higgins, A., . . . Rudland, P. (2006). Association of S100A4 and osteopontin with specific prognostic factors and survival of patients with minimally invasive breast cancer. CLINICAL CANCER RESEARCH, 12(4), 1192-1200. doi:10.1158/1078-0432.CCR-05-1580
Induction of metastasis by S100P in a rat mammary model and its association with poor survival of breast cancer patients
Wang, G. Z., Platt-Higgins, A., Carroll, J., Rudland, S. D., Winstanley, J., Barraclough, R., & Rudland, P. S. (2006). Induction of metastasis by S100P in a rat mammary model and its association with poor survival of breast cancer patients. CANCER RESEARCH, 66(2), 1199-1207. doi:10.1158/0008-5472.CAN-05-2605
'Association of S100A4 and osteopontin with specific prognostic factors and survival of patients with minimally invasive breast cancer'
de Silva Rudland, S., Martin, L., Roshanlall, C., Winstanley, J., Leinster, S., Platt-Higgins, A., . . . Rudland, P. (2006). 'Association of S100A4 and osteopontin with specific prognostic factors and survival of patients with minimally invasive breast cancer'. Clinical Cancer Research, 12(4), 1192-2000.
2005
Human homologue of cement gland protein, a novel metastasis inducer associated with breast carcinomas
Liu, D., Rudland, P. S., Sibson, D. R., Platt-Higgins, A., & Barraclough, R. (2005). Human homologue of cement gland protein, a novel metastasis inducer associated with breast carcinomas. CANCER RESEARCH, 65(9), 3796-3805. doi:10.1158/0008-5472.CAN-04-3823
2004
Ets gene PEA3 cooperates with beta-catenin-Lef-1 and c-Jun in regulation of osteopontin transcription.
El-Tanani, M., Platt-Higgins, A., Rudland, P. S., & Campbell, F. C. (2004). Ets gene PEA3 cooperates with beta-catenin-Lef-1 and c-Jun in regulation of osteopontin transcription.. The Journal of biological chemistry, 279(20), 20794-20806. doi:10.1074/jbc.m311131200
2002
Prognostic significance of the metastasis-associated protein osteopontin in human breast cancer
Rudland, P. S., Platt-Higgins, A., El-Tanani, M., Rudland, S. D. S., Barraclough, R., Winstanley, J. H. R., . . . West, C. R. (2002). Prognostic significance of the metastasis-associated protein osteopontin in human breast cancer. CANCER RESEARCH, 62(12), 3417-3427. Retrieved from https://www.webofscience.com/
2000
Variant estrogen receptor alpha mRNAs in human breast cancer specimens.
Anandappa, S. Y., Sibson, R., Platt-Higgins, A., Winstanley, J. H., Rudland, P. S., & Barraclough, R. (2000). Variant estrogen receptor alpha mRNAs in human breast cancer specimens.. International journal of cancer, 88(2), 209-216. doi:3.0.co;2-m">10.1002/1097-0215(20001015)88:2<209::aid-ijc10>3.0.co;2-m
Comparison of the metastasis-inducing protein S100A4 (p9Ka) with other prognostic markers in human breast cancer
Platt-Higgins, A. M., Renshaw, C. A., West, C. R., Winstanley, J. H. R., Rudland, S. D., Barraclough, R., & Rudland, P. S. (2000). Comparison of the metastasis-inducing protein S100A4 (p9Ka) with other prognostic markers in human breast cancer. INTERNATIONAL JOURNAL OF CANCER, 89(2), 198-208. doi:3.0.CO;2-L">10.1002/(SICI)1097-0215(20000320)89:2<198::AID-IJC16>3.0.CO;2-L
Prognostic significance of the metastasis-inducing protein S100A4 (p9Ka) in human breast cancer
Rudland, P. S., Platt-Higgins, A., Renshaw, C., West, C. R., Winstanley, J. H. R., Robertson, L., & Barraclough, R. (2000). Prognostic significance of the metastasis-inducing protein S100A4 (p9Ka) in human breast cancer. CANCER RESEARCH, 60(6), 1595-1603. Retrieved from https://www.webofscience.com/
Expression of calcium binding protein S100A2 in breast lesions
Liu, D., Rudland, P. S., Sibson, D. R., Platt-Higgins, A., & Barraclough, R. (2000). Expression of calcium binding protein S100A2 in breast lesions. BRITISH JOURNAL OF CANCER, 83(11), 1473-1479. doi:10.1054/bjoc.2000.1488
1999
Development of hyperplasias, preneoplasias, and mammary tumors in MMTV-c-erbB-2 and MMTV-TGFalpha transgenic rats.
Davies, B. R., Platt-Higgins, A. M., Schmidt, G., & Rudland, P. S. (1999). Development of hyperplasias, preneoplasias, and mammary tumors in MMTV-c-erbB-2 and MMTV-TGFalpha transgenic rats.. The American journal of pathology, 155(1), 303-314. doi:10.1016/s0002-9440(10)65124-3
1998
Human S100A4(p9Ka) induces the metastatic phenotype upon benign tumour cells
Lloyd, B. H., Platt-Higgins, A., Rudland, P. S., & Barraclough, R. (1998). Human S100A4(p9Ka) induces the metastatic phenotype upon benign tumour cells. ONCOGENE, 17(4), 465-473. doi:10.1038/sj.onc.1201948
Cytoplasmic staining of c-erbB-2 is not associated with the presence of detectable c-erbB-2 mRNA in breast cancer specimens
Taylor, S. L., Platt-Higgins, A., Rudland, P. S., Winstanley, J. H. R., & Barraclough, R. (1998). Cytoplasmic staining of c-erbB-2 is not associated with the presence of detectable c-erbB-2 mRNA in breast cancer specimens. INTERNATIONAL JOURNAL OF CANCER, 76(4), 459-463. doi:3.0.CO;2-Q">10.1002/(SICI)1097-0215(19980518)76:4<459::AID-IJC2>3.0.CO;2-Q
1995
IMMUNOCYTOCHEMICAL DISTRIBUTION OF THE CALCIUM-BINDING PROTEIN P9KA IN NORMAL RAT-TISSUES - VARIATION IN THE CELLULAR LOCATION IN DIFFERENT TISSUES
GIBBS, F. E. M., BARRACLOUGH, R., PLATTHIGGINS, A., RUDLAND, P. S., WILKINSON, M. C., & PARRY, E. W. (1995). IMMUNOCYTOCHEMICAL DISTRIBUTION OF THE CALCIUM-BINDING PROTEIN P9KA IN NORMAL RAT-TISSUES - VARIATION IN THE CELLULAR LOCATION IN DIFFERENT TISSUES. JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY, 43(2), 169-180. doi:10.1177/43.2.7822773
1994
Immunolocalization of alpha-transforming growth factor in the developing rat mammary gland in vivo, rat mammary cells in vitro and in human breast diseases.
McAndrew, J., Rudland, P. S., Platt-Higgins, A. M., & Smith, J. A. (1994). Immunolocalization of alpha-transforming growth factor in the developing rat mammary gland in vivo, rat mammary cells in vitro and in human breast diseases.. The Histochemical journal, 26(4), 355-366. doi:10.1007/bf00157769
1993
IMMUNOCYTOCHEMICAL IDENTIFICATION OF BASIC FIBROBLAST GROWTH-FACTOR IN THE DEVELOPING RAT MAMMARY-GLAND - VARIATIONS IN LOCATION ARE DEPENDENT ON GLANDULAR STRUCTURE AND DIFFERENTIATION
RUDLAND, P. S., PLATTHIGGINS, A. M., WILKINSON, M. C., & FERNIG, D. G. (1993). IMMUNOCYTOCHEMICAL IDENTIFICATION OF BASIC FIBROBLAST GROWTH-FACTOR IN THE DEVELOPING RAT MAMMARY-GLAND - VARIATIONS IN LOCATION ARE DEPENDENT ON GLANDULAR STRUCTURE AND DIFFERENTIATION. JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY, 41(6), 887-898. doi:10.1177/41.6.7686196
Immunohistochemical detection of cytokeratin 14, Type IV collagen and laminin in 100 cases (invasive) ductal carcinoma of no special type and correlation with histological grade
Aung, W., Zakhour, H. D., Platt-Higgins, A., & Rudland, P. S. (1993). Immunohistochemical detection of cytokeratin 14, Type IV collagen and laminin in 100 cases (invasive) ductal carcinoma of no special type and correlation with histological grade. The Breast, 2(3), 165-170. doi:10.1016/0960-9776(93)90061-j
Prognostic significance of cathepsin-D in patients with breast cancer.
Winstanley, J. H., Leinster, S. J., Cooke, T. G., Westley, B. R., Platt-Higgins, A. M., & Rudland, P. S. (1993). Prognostic significance of cathepsin-D in patients with breast cancer.. British journal of cancer, 67(4), 767-772. doi:10.1038/bjc.1993.139
1991
Morphogenetic behavior of simian virus 40-transformed human mammary epithelial stem cell lines on collagen gels.
Rudland, P. S., Ollerhead, G. E., & Platt-Higgins, A. M. (1991). Morphogenetic behavior of simian virus 40-transformed human mammary epithelial stem cell lines on collagen gels.. In vitro cellular & developmental biology : journal of the Tissue Culture Association, 27A(2), 103-112. doi:10.1007/bf02630995
The long term prognostic significance of c-erbB-2 in primary breast cancer.
Winstanley, J., Cooke, T., Murray, G. D., Platt-Higgins, A., George, W. D., Holt, S., . . . Rudland, P. S. (1991). The long term prognostic significance of c-erbB-2 in primary breast cancer.. British journal of cancer, 63(3), 447-450. doi:10.1038/bjc.1991.103