Photo of Dr Laura Swan

Dr Laura Swan PhD

Molecular & Physiology Cell Signalling

    Publications

    Selected Publications

    1. Mutations in INPP5K Cause a Form of Congenital Muscular Dystrophy Overlapping Marinesco-Sjögren Syndrome and Dystroglycanopathy (Journal article - 2017)
    2. Mutations in INPP5K, Encoding a Phosphoinositide 5-Phosphatase, Cause Congenital Muscular Dystrophy with Cataracts and Mild Cognitive Impairment (Journal article - 2017)
    3. Recognition of the F&H motif by the Lowe syndrome protein OCRL (Journal article - 2011)
    4. Two closely related endocytic proteins that share a common OCRL-binding motif with APPL1 (Journal article - 2010)
    5. Wnt3a-mediated formation of phosphatidylinositol 4,5-bisphosphate regulates LRP6 phosphorylation (Journal article - 2008)

    2020

    The complex interplay between kidney injury and inflammation (Journal article)

    McWilliam, S. J., Wright, R. D., Welsh, G. I., Tuffin, J., Budge, K. L., Swan, L., . . . Oni, L. (n.d.). The complex interplay between kidney injury and inflammation. Clinical Kidney Journal. doi:10.1093/ckj/sfaa164

    DOI: 10.1093/ckj/sfaa164

    Live imaging of intra-lysosome pH in cell lines and primary neuronal culture using a novel genetically encoded biosensor (Journal article)

    Ponsford, A. H., Ryan, T. A., Raimondi, A., Cocucci, E., Wycislo, S. A., Fröhlich, F., . . . Stagi, M. (n.d.). Live imaging of intra-lysosome pH in cell lines and primary neuronal culture using a novel genetically encoded biosensor. Autophagy, 1-19. doi:10.1080/15548627.2020.1771858

    DOI: 10.1080/15548627.2020.1771858

    2019

    Lowe syndrome-linked endocytic adaptors direct membrane cycling kinetics with OCRL in Dictyostelium discoideum. (Journal article)

    Luscher, A., Fröhlich, F., Barisch, C., Littlewood, C., Metcalfe, J., Leuba, F., . . . Swan, L. E. (2019). Lowe syndrome-linked endocytic adaptors direct membrane cycling kinetics with OCRL in Dictyostelium discoideum.. Molecular biology of the cell, 30(17), 2268-2282. doi:10.1091/mbc.E18-08-0510

    DOI: 10.1091/mbc.E18-08-0510

    2018

    Multifocal demyelinating motor neuropathy and hamartoma syndrome associated with a de novo PTEN mutation. (Journal article)

    Bansagi, B., Phan, V., Baker, M. R., O'Sullivan, J., Jennings, M. J., Whittaker, R. G., . . . Horvath, R. (2018). Multifocal demyelinating motor neuropathy and hamartoma syndrome associated with a de novo PTEN mutation. Neurology, 90(21), e1842-e1848. doi:10.1212/WNL.0000000000005566

    DOI: 10.1212/wnl.0000000000005566

    Correction to: Clathrin-Mediated Endocytosis: Methods and Protocols. (Book)

    Swan, L. E. (2018). Correction to: Clathrin-Mediated Endocytosis: Methods and Protocols. (Vol. 1847). doi:10.1007/978-1-4939-8719-1_19

    DOI: 10.1007/978-1-4939-8719-1_19

    Purification of Clathrin-Coated Vesicles from Adult Rat Brain. (Book)

    Giovedì, S. (2018). Purification of Clathrin-Coated Vesicles from Adult Rat Brain. (Vol. 1847). doi:10.1007/978-1-4939-8719-1_1

    DOI: 10.1007/978-1-4939-8719-1_1

    2017

    Mutations in INPP5K Cause a Form of Congenital Muscular Dystrophy Overlapping Marinesco-Sjögren Syndrome and Dystroglycanopathy (Journal article)

    Osborn, D. P. S., Pond, H. L., Mazaheri, N., Desjardin, J., Munn, C. J., Muschref, K., . . . Manizini, M. C. (2017). Mutations in INPP5K Cause a Form of Congenital Muscular Dystrophy Overlapping Marinesco-Sjögren Syndrome and Dystroglycanopathy. American Journal of Human Genetics, 100(3), 537-545. doi:10.1016/j.ajhg.2017.01.019

    DOI: 10.1016/j.ajhg.2017.01.019

    Mutations in INPP5K, Encoding a Phosphoinositide 5-Phosphatase, Cause Congenital Muscular Dystrophy with Cataracts and Mild Cognitive Impairment (Journal article)

    Weissner, M., Roos, A., Munn, C. J., Viswanathan, R., Whyte, T., Cox, D., . . . Senderek, J. (2017). Mutations in INPP5K, Encoding a Phosphoinositide 5-Phosphatase, Cause Congenital Muscular Dystrophy with Cataracts and Mild Cognitive Impairment. American Journal of Human Genetics, 100(3), 523-536. doi:10.1016/j.ajhg.2017.01.024

    DOI: 10.1016/j.ajhg.2017.01.024

    2016

    Exciting cells and controlling heartbeats – could optogenetics create drug-free treatments? (Internet publication)

    Swan, L. E. (2016). Exciting cells and controlling heartbeats – could optogenetics create drug-free treatments?. Retrieved from https://theconversation.com/

    2015

    Low cost production of 3D-printed devices and electrostimulation chambers for the culture of primary neurons (Journal article)

    Wardyn, J., Sanderson, C., Swan, L., & Stagi, M. (2015). Low cost production of 3D-printed devices and electrostimulation chambers for the culture of primary neurons. Journal of Neuroscience Methods, 251, 17-23. doi:10.1016/j.jneumeth.2015.05.001

    DOI: 10.1016/j.jneumeth.2015.05.001

    2013

    Initiation of clathrin-mediated endocytosis: All you need is two? (Journal article)

    Swan, L. E. (2013). Initiation of clathrin-mediated endocytosis: All you need is two?. BIOESSAYS, 35(5), 425-429. doi:10.1002/bies.201200129

    DOI: 10.1002/bies.201200129

    2011

    Recognition of the F&H motif by the Lowe syndrome protein OCRL (Journal article)

    Pirruccello, M., Swan, L. E., Folta-Stogniew, E., & De Camilli, P. (2011). Recognition of the F&H motif by the Lowe syndrome protein OCRL. NATURE STRUCTURAL & MOLECULAR BIOLOGY, 18(7), 789-U63. doi:10.1038/nsmb.2071

    DOI: 10.1038/nsmb.2071

    2010

    Two closely related endocytic proteins that share a common OCRL-binding motif with APPL1 (Journal article)

    Swan, L. E., Tomasini, L., Pirruccello, M., Lunardi, J., & De Camilli, P. (2010). Two closely related endocytic proteins that share a common OCRL-binding motif with APPL1. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 107(8), 3511-3516. doi:10.1073/pnas.0914658107

    DOI: 10.1073/pnas.0914658107

    2009

    An Unnatural PIP Simulates Growth Factor Signaling (Journal article)

    Swan, L. (2009). An Unnatural PIP Simulates Growth Factor Signaling. CHEMISTRY & BIOLOGY, 16(11), 1127-1128. doi:10.1016/j.chembiol.2009.11.003

    DOI: 10.1016/j.chembiol.2009.11.003

    Tweek, an Evolutionarily Conserved Protein, Is Required for Synaptic Vesicle Recycling (Journal article)

    Verstreken, P., Ohyama, T., Haueter, C., Habets, R. L. P., Lin, Y. Q., Swan, L. E., . . . Bellen, H. J. (2009). Tweek, an Evolutionarily Conserved Protein, Is Required for Synaptic Vesicle Recycling. NEURON, 63(2), 203-215. doi:10.1016/j.neuron.2009.06.017

    DOI: 10.1016/j.neuron.2009.06.017

    2008

    Wnt3a-mediated formation of phosphatidylinositol 4,5-bisphosphate regulates LRP6 phosphorylation (Journal article)

    Pan, W., Choi, S. -C., Wang, H., Qin, Y., Volpicelli-Daley, L., Swan, L., . . . Wu, D. (2008). Wnt3a-mediated formation of phosphatidylinositol 4,5-bisphosphate regulates LRP6 phosphorylation. SCIENCE, 321(5894), 1350-1353. doi:10.1126/science.1160741

    DOI: 10.1126/science.1160741

    2006

    Complex interaction of Drosophila GRIP PDZ domains and Echinoid during muscle morphogenesis (Journal article)

    Swan, L. E., Schmidt, M., Schwarz, T., Ponimaskin, E., Prange, U., Boeckers, T., . . . Sigrist, S. J. (2006). Complex interaction of Drosophila GRIP PDZ domains and Echinoid during muscle morphogenesis. EMBO JOURNAL, 25(15), 3640-3651. doi:10.1038/sj.emboj.7601216

    DOI: 10.1038/sj.emboj.7601216

    2004

    Altered cellular distribution of iron in rat cerebral cortex during the oestrous cycle (Journal article)

    Bishop, G. M., Swan, L. E., & Robinson, S. R. (2004). Altered cellular distribution of iron in rat cerebral cortex during the oestrous cycle. JOURNAL OF NEURAL TRANSMISSION, 111(2), 159-165. doi:10.1007/s00702-003-0098-3

    DOI: 10.1007/s00702-003-0098-3

    A glutamate receptor-interacting protein homolog organizes muscle guidance in Drosophila (Journal article)

    Swan, L. E., Wichmann, C., Prange, U., Schmid, A., Schmidt, M., Schwarz, T., . . . Sigrist, S. J. (2004). A glutamate receptor-interacting protein homolog organizes muscle guidance in Drosophila. GENES & DEVELOPMENT, 18(2), 223-237. doi:10.1101/gad.287604

    DOI: 10.1101/gad.287604

    2002

    The antidepressant tianeptine persistently modulates glutamate receptor currents of the hippocampal CA3 commissural associational synapse in chronically stressed rats (Journal article)

    Kole, M. H. P., Swan, L., & Fuchs, E. (2002). The antidepressant tianeptine persistently modulates glutamate receptor currents of the hippocampal CA3 commissural associational synapse in chronically stressed rats. EUROPEAN JOURNAL OF NEUROSCIENCE, 16(5), 807-816. doi:10.1046/j.1460-9568.2002.02136.x

    DOI: 10.1046/j.1460-9568.2002.02136.x