Our research addresses the safety, efficacy and mechanisms of action of cell-based regenerative medicine therapies for the treatment of renal and neurological diseases. We develop non-invasive imaging strategies to assess the behaviour of administered cells and their effects on organ function in vivo, and use advanced microscopy and histological techniques to assess cell fate and the host tissue response. We also investigate the role of biomaterials in the regulation of stem cell behaviour.
I am interested in scientific integrity and oppose the inappropriate use of cell therapies in patients. My concerns regarding some high profile cases have been reported in Science, the BMJ, BBC, the Telegraph, Private Eye and the For Better Science blog.