2023
da Silva, T. B., Rendra, E., David, C. A. W., Bieback, K., Cross, M. J., Wilm, B., . . . Murray, P. (2023). Umbilical cord mesenchymal stromal cell-derived extracellular vesicles lack the potency to immunomodulate human monocyte-derived macrophages in vitro.. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 167, 115624. doi:10.1016/j.biopha.2023.115624DOI: 10.1016/j.biopha.2023.115624
Koukorava, C., Ward, K., Ahmed, K., Almaghrabi, S., Dauleh, S., Pereira, S. M., . . . Wilm, B. (n.d.). Mesothelial Cells Exhibit Characteristics of Perivascular Cells in an In Vitro Angiogenesis Assay. Cells, 12(20), 2436. doi:10.3390/cells12202436DOI: 10.3390/cells12202436
Powell, S. G., Sharma, P., Masterson, S., Wyatt, J., Arshad, I., Ahmed, S., . . . Hapangama, D. K. (2023). Vascularisation in Deep Endometriosis: A Systematic Review with Narrative Outcomes. CELLS, 12(9). doi:10.3390/cells12091318DOI: 10.3390/cells12091318
Mondru, A. K., Aljasir, M. A., Alrumayh, A., Nithianandarajah, G. N., Ahmed, K., Muller, J., . . . Cross, M. J. (2023). VEGF Stimulates Activation of ERK5 in the Absence of C-Terminal Phosphorylation Preventing Nuclear Localization and Facilitating AKT Activation in Endothelial Cells. CELLS, 12(6). doi:10.3390/cells12060967DOI: 10.3390/cells12060967
2022
Muñiz-García, A., Wilm, B., Murray, P., & Cross, M. J. (n.d.). Extracellular Vesicles from Human Umbilical Cord-Derived MSCs Affect Vessel Formation In Vitro and Promote VEGFR2-Mediated cell Survival. Cells, 11(23), 3750. doi:10.3390/cells11233750DOI: 10.3390/cells11233750
Zhang, J., Pearson, A. J., Sabherwal, N., Telfer, B. A., Ali, N., Kan, K., . . . Tournier, C. (2022). Inhibiting ERK5 Overcomes Breast Cancer Resistance to Anti-HER2 Therapy By Targeting the G1–S Cell-Cycle Transition. Cancer Research Communications, 2(3), 131-145. doi:10.1158/2767-9764.crc-21-0089DOI: 10.1158/2767-9764.crc-21-0089
2021
Development of a multicellular human cardiac spheroid to study drug-induced cardiotoxicity. (Poster)
Koukorava, C., Haddrick, M., & Cross, M. (2021). Development of a multicellular human cardiac spheroid to study drug-induced cardiotoxicity.. Poster session presented at the meeting of 71st Annual British Microcirculation and Vascular Biology Society Conference.
2019
Thaventhiran, T., Wong, W., Alghanem, A. F., Alhumeed, N., Aljasir, M. A., Ramsey, S., . . . Sathish, J. G. (2019). CD28 Superagonistic Activation of T Cells Induces a Tumor Cell-Like Metabolic Program.. Monoclonal antibodies in immunodiagnosis and immunotherapy, 38(2), 60-69. doi:10.1089/mab.2018.0042DOI: 10.1089/mab.2018.0042
2018
Dickens, D., Rädisch, S., Chiduza, G. N., Giannoudis, A., Cross, M. J., Malik, H., . . . Nies, A. T. (2018). Cellular Uptake of the Atypical Antipsychotic Clozapine Is a Carrier-Mediated Process. Molecular Pharmaceutics, 15(8), 3557-3572. doi:10.1021/acs.molpharmaceut.8b00547DOI: 10.1021/acs.molpharmaceut.8b00547
Park, B. K., & Goldring, C. (2018). Innovative Organotypic In Vitro Models for Safety Assessment: Aligning with regulatory requirements and understanding models of the heart, skin and liver as paradigms. Archives of Toxicology, 92(2), 557-569. doi:10.1007/s00204-018-2152-9DOI: 10.1007/s00204-018-2152-9
Leading-Edge Approaches for In Vitro Hepatotoxicity Evaluation (Chapter)
LeCluyse, E. L., Norona, L. M., Akingbasote, J. A., Howell, L. S., Woodhead, J. L., Cross, M. J., . . . Goldring, C. E. (2018). Leading-Edge Approaches for In Vitro Hepatotoxicity Evaluation. In Comprehensive Toxicology, Third Edition: Volume 1-15 (Vol. 2, pp. V2-651-V2-712). doi:10.1016/B978-0-12-801238-3.64267-8DOI: 10.1016/B978-0-12-801238-3.64267-8
Leading-Edge Approaches for In Vitro Hepatotoxicity Evaluation (Chapter)
LeCluyse, E. L., Norona, L. M., Akingbasote, J. A., Howell, L. S., Woodhead, J. L., Cross, M. J., . . . Goldring, C. E. (2018). Leading-Edge Approaches for In Vitro Hepatotoxicity Evaluation. In Comprehensive Toxicology (pp. 651-712). Elsevier. doi:10.1016/b978-0-12-801238-3.64267-8DOI: 10.1016/b978-0-12-801238-3.64267-8
Wilkinson, E. L., Sidaway, J. E., & Cross, M. J. (2018). Statin regulated ERK5 stimulates tight junction formation and reduces permeability in human cardiac endothelial cells. JOURNAL OF CELLULAR PHYSIOLOGY, 233(01), 186-200. doi:10.1002/jcp.26064DOI: 10.1002/jcp.26064
2017
Alghanem, A. F., Wilkinson, E. L., Emmett, M. S., Aljasir, M. A., Holmes, K., Rothermel, B. A., . . . Cross, M. J. (2017). RCAN1.4 regulates VEGFR-2 internalisation, cell polarity and migration in human microvascular endothelial cells. Angiogenesis, 20(3), 341-358. doi:10.1007/s10456-017-9542-0DOI: 10.1007/s10456-017-9542-0
2016
Wilkinson, E. L., Sidaway, J. E., & Cross, M. J. (2016). Cardiotoxic drugs Herceptin and doxorubicin inhibit cardiac microvascular endothelial cell barrier formation resulting in increased drug permeability. Biology open, 5(10), 1362-1370. doi:10.1242/bio.020362DOI: 10.1242/bio.020362
Ravenscroft, S. M., Pointon, A., Williams, A. W., Cross, M. J., & Sidaway, J. E. (2016). Cardiac Non-myocyte Cells Show Enhanced Pharmacological Function Suggestive of Contractile Maturity in Stem Cell Derived Cardiomyocyte Microtissues. TOXICOLOGICAL SCIENCES, 152(1), 99-112. doi:10.1093/toxsci/kfw069DOI: 10.1093/toxsci/kfw069
2015
Concise Review: Workshop Review: Understanding and Assessing the Risks of Stem Cell-Based Therapies (Journal article)
Heslop, J. A., Hammond, T. G., Santeramo, I., Piella, A. T., Hopp, I., Zhou, J., . . . Park, B. K. (2015). Concise Review: Workshop Review: Understanding and Assessing the Risks of Stem Cell-Based Therapies. STEM CELLS TRANSLATIONAL MEDICINE, 4(4), 389-400. doi:10.5966/sctm.2014-0110DOI: 10.5966/sctm.2014-0110
Physiological, pharmacological and toxicological considerations of drug-induced structural cardiac injury (Journal article)
Cross, M. J., Berridge, B. R., Clements, P. J. M., Cove-Smith, L., Force, T. L., Hoffmann, P., . . . Park, B. K. (2015). Physiological, pharmacological and toxicological considerations of drug-induced structural cardiac injury. BRITISH JOURNAL OF PHARMACOLOGY, 172(4), 957-974. doi:10.1111/bph.12979DOI: 10.1111/bph.12979
Analysis of VEGF-Mediated ERK5 Activity in Endothelial Cells. (Journal article)
Nithianandarajah-Jones, G. N., & Cross, M. J. (2015). Analysis of VEGF-Mediated ERK5 Activity in Endothelial Cells.. Methods in molecular biology (Clifton, N.J.), 1332, 133-142. doi:10.1007/978-1-4939-2917-7_9DOI: 10.1007/978-1-4939-2917-7_9
Brusatol provokes a rapid and transient inhibition of Nrf2 signaling and sensitizes mammalian cells to chemical toxicity-implications for therapeutic targeting of Nrf2. (Journal article)
Olayanju, A., Copple, I., Bryan, H. K., Edge, G. T., Sison-Young, R., Wong, M. W., . . . Park, K. (2015). Brusatol provokes a rapid and transient inhibition of Nrf2 signaling and sensitizes mammalian cells to chemical toxicity-implications for therapeutic targeting of Nrf2.. Free Radical Biology & Medicine, 78, 202-212.
Brusatol provokes a rapid and transient inhibition of Nrf2 signaling and sensitizes mammalian cells to chemical toxicity—implications for therapeutic targeting of Nrf2 (Journal article)
Olayanju, A., Copple, I. M., Bryan, H. K., Edge, G. T., Sison, R. L., Wong, M. W., . . . Park, B. K. (2015). Brusatol provokes a rapid and transient inhibition of Nrf2 signaling and sensitizes mammalian cells to chemical toxicity—implications for therapeutic targeting of Nrf2. Free Radical Biology and Medicine, 78, 202-212. doi:10.1016/j.freeradbiomed.2014.11.003DOI: 10.1016/j.freeradbiomed.2014.11.003
2014
The role of ERK5 in endothelial cell function (Journal article)
Nithianandarajah-Jones, G. N., Wilm, B., Goldring, C. E. P., Mueller, J., & Cross, M. J. (2014). The role of ERK5 in endothelial cell function. BIOCHEMICAL SOCIETY TRANSACTIONS, 42, 1584-1589. doi:10.1042/BST20140276DOI: 10.1042/BST20140276
Failure to upregulate cell surface PD-1 is associated with dysregulated stimulation of T cells by TGN1412-like CD28 superagonist (Journal article)
Thaventhiran, T., Alhumeed, N., Yeang, H. X. A., Sethu, S., Downey, J. S., Alghanem, A. F., . . . Sathish, J. G. (2014). Failure to upregulate cell surface PD-1 is associated with dysregulated stimulation of T cells by TGN1412-like CD28 superagonist. MABS, 6(5), 1290-1299. doi:10.4161/mabs.29758DOI: 10.4161/mabs.29758
2013
Safety pharmacology - Current and emerging concepts (Journal article)
Hamdam, J., Sethu, S., Smith, T., Alfirevic, A., Alhaidari, M., Atkinson, J., . . . Goldring, C. (2013). Safety pharmacology - Current and emerging concepts. TOXICOLOGY AND APPLIED PHARMACOLOGY, 273(2), 229-241. doi:10.1016/j.taap.2013.04.039DOI: 10.1016/j.taap.2013.04.039
Phenotypic profiling of structural cardiotoxins in vitro reveals dependency on multiple mechanisms of toxicity. (Journal article)
Pointon, A., Abi-Gerges, N., Cross, M. J., & Sidaway, J. E. (2013). Phenotypic profiling of structural cardiotoxins in vitro reveals dependency on multiple mechanisms of toxicity.. Toxicological sciences : an official journal of the Society of Toxicology, 132(2), 317-326. doi:10.1093/toxsci/kft005DOI: 10.1093/toxsci/kft005
2012
ERK5: Structure, regulation and function (Journal article)
Nithianandarajah-Jones, G. N., Wilm, B., Goldring, C. E. P., Mueller, J., & Cross, M. J. (2012). ERK5: Structure, regulation and function. CELLULAR SIGNALLING, 24(11), 2187-2196. doi:10.1016/j.cellsig.2012.07.007DOI: 10.1016/j.cellsig.2012.07.007
Human pluripotent stem cells for modeling toxicity. (Journal article)
Sison-Young, R. L. C., Kia, R., Heslop, J., Kelly, L., Rowe, C., Cross, M. J., . . . Goldring, C. E. P. (2012). Human pluripotent stem cells for modeling toxicity.. Advances in pharmacology (San Diego, Calif.), 63, 207-256. doi:10.1016/b978-0-12-398339-8.00006-9DOI: 10.1016/b978-0-12-398339-8.00006-9
2011
How can we improve our understanding of cardiovascular safety liabilities to develop safer medicines? (Journal article)
Laverty, H. G., Benson, C., Cartwright, E. J., Cross, M. J., Garland, C., Hammond, T., . . . Valentin, J. P. (2011). How can we improve our understanding of cardiovascular safety liabilities to develop safer medicines?. BRITISH JOURNAL OF PHARMACOLOGY, 163(4), 675-693. doi:10.1111/j.1476-5381.2011.01255.xDOI: 10.1111/j.1476-5381.2011.01255.x
Exogenous Recombinant Dimeric Neuropilin-1 Is Sufficient to Drive Angiogenesis (Journal article)
Uniewicz, K. A., Cross, M. J., & Fernig, D. G. (2011). Exogenous Recombinant Dimeric Neuropilin-1 Is Sufficient to Drive Angiogenesis. JOURNAL OF BIOLOGICAL CHEMISTRY, 286(1), 12-23. doi:10.1074/jbc.M110.190801DOI: 10.1074/jbc.M110.190801
2010
ERK5 is required for VEGF-mediated survival and tubular morphogenesis of primary human microvascular endothelial cells (Journal article)
Roberts, O. L., Holmes, K., Müller, J., Cross, D. A. E., & Cross, M. J. (2010). ERK5 is required for VEGF-mediated survival and tubular morphogenesis of primary human microvascular endothelial cells. Journal of Cell Science, 123(19), 3413. doi:10.1242/jcs.080663DOI: 10.1242/jcs.080663
ERK5 is required for VEGF-mediated survival and tubular morphogenesis of primary human microvascular endothelial cells. (Journal article)
Roberts, O. L., Holmes, K., Müller, J., Cross, D. A. E., & Cross, M. J. (2010). ERK5 is required for VEGF-mediated survival and tubular morphogenesis of primary human microvascular endothelial cells.. Journal of cell science, 123(Pt 18), 3189-3200. doi:10.1242/jcs.072801DOI: 10.1242/jcs.072801
VEGF Stimulates RCAN1.4 Expression in Endothelial Cells via a Pathway Requiring Ca<SUP>2+</SUP>/Calcineurin and Protein Kinase C-δ (Journal article)
Holmes, K., Chapman, E., See, V., & Cross, M. J. (2010). VEGF Stimulates RCAN1.4 Expression in Endothelial Cells via a Pathway Requiring Ca<SUP>2+</SUP>/Calcineurin and Protein Kinase C-δ. PLOS ONE, 5(7). doi:10.1371/journal.pone.0011435DOI: 10.1371/journal.pone.0011435
Holmes, K., Williams, C. M., Chapman, E. A., & Cross, M. J. (2010). Detection of siRNA induced mRNA silencing by RT-qPCR: considerations for experimental design.. BMC research notes, 3, 53. doi:10.1186/1756-0500-3-53DOI: 10.1186/1756-0500-3-53
2009
ERK5 and the regulation of endothelial cell function. (Journal article)
Roberts, O. L., Holmes, K., Müller, J., Cross, D. A. E., & Cross, M. J. (2009). ERK5 and the regulation of endothelial cell function.. Biochemical Society transactions, 37(Pt 6), 1254-1259. doi:10.1042/bst0371254DOI: 10.1042/bst0371254
Transcriptional profiling reveals a critical role for tyrosine phosphatase VE-PTP in regulation of VEGFR2 activity and endothelial cell morphogenesis. (Journal article)
Mellberg, S., Dimberg, A., Bahram, F., Hayashi, M., Rennel, E., Ameur, A., . . . Claesson-Welsh, L. (2009). Transcriptional profiling reveals a critical role for tyrosine phosphatase VE-PTP in regulation of VEGFR2 activity and endothelial cell morphogenesis.. FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 23(5), 1490-1502. doi:10.1096/fj.08-123810DOI: 10.1096/fj.08-123810
2007
Vascular endothelial growth factor receptor-2: structure, function, intracellular signalling and therapeutic inhibition. (Journal article)
Holmes, K., Roberts, O. L., Thomas, A. M., & Cross, M. J. (2007). Vascular endothelial growth factor receptor-2: structure, function, intracellular signalling and therapeutic inhibition.. Cellular signalling, 19(10), 2003-2012. doi:10.1016/j.cellsig.2007.05.013DOI: 10.1016/j.cellsig.2007.05.013
Endocan is a VEGF-A and PI3K regulated gene with increased expression in human renal cancer. (Journal article)
Rennel, E., Mellberg, S., Dimberg, A., Petersson, L., Botling, J., Ameur, A., . . . Gerwins, P. (2007). Endocan is a VEGF-A and PI3K regulated gene with increased expression in human renal cancer.. Experimental cell research, 313(7), 1285-1294. doi:10.1016/j.yexcr.2007.01.021DOI: 10.1016/j.yexcr.2007.01.021
Vascular Endothelial Growth Factor Receptor-2: Structure, function, intracellular signaling and therapeutic inhibition (Journal article)
Holmes, K., Roberts, O. L., Thomas, A. M., & Cross, M. J. (2007). Vascular Endothelial Growth Factor Receptor-2: Structure, function, intracellular signaling and therapeutic inhibition. Unknown Journal, 10(19), 2003-2012.
2004
The adaptor protein shb binds to tyrosine 1175 in vascular endothelial growth factor (VEGF) receptor-2 and regulates VEGF-dependent cellular migration. (Journal article)
Holmqvist, K., Cross, M. J., Rolny, C., Hägerkvist, R., Rahimi, N., Matsumoto, T., . . . Welsh, M. (2004). The adaptor protein shb binds to tyrosine 1175 in vascular endothelial growth factor (VEGF) receptor-2 and regulates VEGF-dependent cellular migration.. The Journal of biological chemistry, 279(21), 22267-22275. doi:10.1074/jbc.m312729200DOI: 10.1074/jbc.m312729200
2003
Regulation of endothelial cell differentiation and transformation by H-Ras. (Journal article)
Rennel, E., Cross, M. J., Klint, P., Bai, X., Arbiser, J. L., & Gerwins, P. (2003). Regulation of endothelial cell differentiation and transformation by H-Ras.. Experimental cell research, 291(1), 189-200. doi:10.1016/s0014-4827(03)00347-1DOI: 10.1016/s0014-4827(03)00347-1
VEGF-receptor signal transduction. (Journal article)
Cross, M. J., Dixelius, J., Matsumoto, T., & Claesson-Welsh, L. (2003). VEGF-receptor signal transduction.. Trends in biochemical sciences, 28(9), 488-494. doi:10.1016/s0968-0004(03)00193-2DOI: 10.1016/s0968-0004(03)00193-2
Differential tyrosine phosphorylation of fibroblast growth factor (FGF) receptor-1 and receptor proximal signal transduction in response to FGF-2 and heparin. (Journal article)
Lundin, L., Rönnstrand, L., Cross, M., Hellberg, C., Lindahl, U., & Claesson-Welsh, L. (2003). Differential tyrosine phosphorylation of fibroblast growth factor (FGF) receptor-1 and receptor proximal signal transduction in response to FGF-2 and heparin.. Experimental cell research, 287(1), 190-198. doi:10.1016/s0014-4827(03)00125-3DOI: 10.1016/s0014-4827(03)00125-3
Endostatin action and intracellular signaling: beta-catenin as a potential target? (Journal article)
Dixelius, J., Cross, M. J., Matsumoto, T., & Claesson-Welsh, L. (2003). Endostatin action and intracellular signaling: beta-catenin as a potential target?. Cancer letters, 196(1), 1-12. doi:10.1016/s0304-3835(03)00267-2DOI: 10.1016/s0304-3835(03)00267-2
Angiostatin and endostatin inhibit endothelial cell migration in response to FGF and VEGF without interfering with specific intracellular signal transduction pathways. (Journal article)
Eriksson, K., Magnusson, P., Dixelius, J., Claesson-Welsh, L., & Cross, M. J. (2003). Angiostatin and endostatin inhibit endothelial cell migration in response to FGF and VEGF without interfering with specific intracellular signal transduction pathways.. FEBS letters, 536(1-3), 19-24. doi:10.1016/s0014-5793(03)00003-6DOI: 10.1016/s0014-5793(03)00003-6
The Shb adaptor protein causes Src-dependent cell spreading and activation of focal adhesion kinase in murine brain endothelial cells. (Journal article)
Holmqvist, K., Cross, M., Riley, D., & Welsh, M. (2003). The Shb adaptor protein causes Src-dependent cell spreading and activation of focal adhesion kinase in murine brain endothelial cells.. Cellular signalling, 15(2), 171-179. doi:10.1016/s0898-6568(02)00076-1DOI: 10.1016/s0898-6568(02)00076-1
Endostatin action and intracellular signaling: -Catenin as a potential target? (Journal article)
Dixelius, J., Cross, M. J., Matsumoto, T., & Claesson-Welsh, L. (2003). Endostatin action and intracellular signaling: -Catenin as a potential target?. Unknown Journal, 1(196), 1-12.
VEGF receptor signal transduction (Journal article)
Cross, M. J., Dixelius, J., Matsumoto, T., & Claesson-Welsh, L. (2003). VEGF receptor signal transduction. Unknown Journal, 9(28), 488-494.
2002
The Shb adaptor protein binds to tyrosine 766 in the FGFR-1 and regulates the Ras/MEK/MAPK pathway via FRS2 phosphorylation in endothelial cells. (Journal article)
Cross, M. J., Lu, L., Magnusson, P., Nyqvist, D., Holmqvist, K., Welsh, M., & Claesson-Welsh, L. (2002). The Shb adaptor protein binds to tyrosine 766 in the FGFR-1 and regulates the Ras/MEK/MAPK pathway via FRS2 phosphorylation in endothelial cells.. Molecular biology of the cell, 13(8), 2881-2893. doi:10.1091/mbc.e02-02-0103DOI: 10.1091/mbc.e02-02-0103
Role of the Src homology 2 domain-containing protein Shb in murine brain endothelial cell proliferation and differentiation. (Journal article)
Lu, L., Holmqvist, K., Cross, M., & Welsh, M. (2002). Role of the Src homology 2 domain-containing protein Shb in murine brain endothelial cell proliferation and differentiation.. Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research, 13(3), 141-148.
Endostatin regulates endothelial cell adhesion and cytoskeletal organization. (Journal article)
Dixelius, J., Cross, M., Matsumoto, T., Sasaki, T., Timpl, R., & Claesson-Welsh, L. (2002). Endostatin regulates endothelial cell adhesion and cytoskeletal organization.. Cancer research, 62(7), 1944-1947.
Endostatin regulates endothelial cell adhesion and cytoskeletal organization (Journal article)
Dixelius, J., Cross, M., Matsumoto, T., Sasaki, T., Timpl, R., & Claesson-Welsh, L. (2002). Endostatin regulates endothelial cell adhesion and cytoskeletal organization. Cancer Research, 62(7), 1844-1947.
2001
FGF and VEGF function in angiogenesis: signalling pathways, biological responses and therapeutic inhibition. (Journal article)
Cross, M. J., & Claesson-Welsh, L. (2001). FGF and VEGF function in angiogenesis: signalling pathways, biological responses and therapeutic inhibition.. Trends in pharmacological sciences, 22(4), 201-207. doi:10.1016/s0165-6147(00)01676-xDOI: 10.1016/s0165-6147(00)01676-x
2000
G protein-coupled receptor-mediated mitogen-activated protein kinase activation through cooperation of Galpha(q) and Galpha(i) signals. (Journal article)
Blaukat, A., Barac, A., Cross, M. J., Offermanns, S., & Dikic, I. (2000). G protein-coupled receptor-mediated mitogen-activated protein kinase activation through cooperation of Galpha(q) and Galpha(i) signals.. Molecular and cellular biology, 20(18), 6837-6848. doi:10.1128/mcb.20.18.6837-6848.2000DOI: 10.1128/mcb.20.18.6837-6848.2000
Tyrosine 766 in the fibroblast growth factor receptor-1 is required for FGF-stimulation of phospholipase C, phospholipase D, phospholipase A(2), phosphoinositide 3-kinase and cytoskeletal reorganisation in porcine aortic endothelial cells. (Journal article)
Cross, M. J., Hodgkin, M. N., Roberts, S., Landgren, E., Wakelam, M. J., & Claesson-Welsh, L. (2000). Tyrosine 766 in the fibroblast growth factor receptor-1 is required for FGF-stimulation of phospholipase C, phospholipase D, phospholipase A(2), phosphoinositide 3-kinase and cytoskeletal reorganisation in porcine aortic endothelial cells.. Journal of cell science, 113 ( Pt 4), 643-651. doi:10.1242/jcs.113.4.643DOI: 10.1242/jcs.113.4.643
1997
Inhibition of phospholipid signalling and proliferation of Swiss 3T3 cells by the wortmannin analogue demethoxyviridin. (Journal article)
Cross, M. J., Hodgkin, M. N., Plumb, J. A., Brunton, V. G., Stewart, A., MacAully, G., . . . Wakelam, M. J. (1997). Inhibition of phospholipid signalling and proliferation of Swiss 3T3 cells by the wortmannin analogue demethoxyviridin.. Biochimica et biophysica acta, 1362(1), 29-38. doi:10.1016/s0925-4439(97)00053-7DOI: 10.1016/s0925-4439(97)00053-7
Role and regulation of phospholipase D activity in normal and cancer cells. (Conference Paper)
Wakelam, M. J., Martin, A., Hodgkin, M. N., Brown, F., Pettitt, T. R., Cross, M. J., . . . Reynolds, J. L. (1997). Role and regulation of phospholipase D activity in normal and cancer cells.. In Advances in enzyme regulation Vol. 37 (pp. 29-34). doi:10.1016/s0065-2571(96)00023-4DOI: 10.1016/s0065-2571(96)00023-4
1996
Stimulation of actin stress fibre formation mediated by activation of phospholipase D. (Journal article)
Cross, M. J., Roberts, S., Ridley, A. J., Hodgkin, M. N., Stewart, A., Claesson-Welsh, L., & Wakelam, M. J. (1996). Stimulation of actin stress fibre formation mediated by activation of phospholipase D.. Current biology : CB, 6(5), 588-597. doi:10.1016/s0960-9822(02)00545-6DOI: 10.1016/s0960-9822(02)00545-6
1995
Wortmannin and its structural analogue demethoxyviridin inhibit stimulated phospholipase A2 activity in Swiss 3T3 cells. Wortmannin is not a specific inhibitor of phosphatidylinositol 3-kinase. (Journal article)
Cross, M. J., Stewart, A., Hodgkin, M. N., Kerr, D. J., & Wakelam, M. J. (1995). Wortmannin and its structural analogue demethoxyviridin inhibit stimulated phospholipase A2 activity in Swiss 3T3 cells. Wortmannin is not a specific inhibitor of phosphatidylinositol 3-kinase.. The Journal of biological chemistry, 270(43), 25352-25355. doi:10.1074/jbc.270.43.25352DOI: 10.1074/jbc.270.43.25352
The roles of multiple pathways in regulating bombesin-stimulated phospholipase D activity in Swiss 3T3 fibroblasts. (Journal article)
Briscoe, C. P., Martin, A., Cross, M., & Wakelam, M. J. (1995). The roles of multiple pathways in regulating bombesin-stimulated phospholipase D activity in Swiss 3T3 fibroblasts.. The Biochemical journal, 306 ( Pt 1), 115-122. doi:10.1042/bj3060115DOI: 10.1042/bj3060115
1993
Phosphatidylcholine hydrolysis: a source of multiple lipid messenger molecules. (Conference Paper)
Wakelam, M. J., Briscoe, C. P., Stewart, A., Pettitt, T. R., Cross, M. J., Paul, A., . . . Hodgkin, M. (1993). Phosphatidylcholine hydrolysis: a source of multiple lipid messenger molecules.. In Biochemical Society transactions Vol. 21 (pp. 874-877). doi:10.1042/bst0210874DOI: 10.1042/bst0210874
Phosphatidylcholine hydrolysis: a multiple messenger generating system. (Journal article)
Wakelam, M. J., Pettitt, T. R., Kaur, P., Briscoe, C. P., Stewart, A., Paul, A., . . . Currie, S. (1993). Phosphatidylcholine hydrolysis: a multiple messenger generating system.. Advances in second messenger and phosphoprotein research, 28, 73-80.
