Photo of Professor Douglas Kell

Professor Douglas Kell CBE, DSc, MA, DPhil, FAAAS, FLSW, FSB

Research Chair in Systems Biology Biochemistry & Systems Biology

    Publications

    2021

    FragNet, a Contrastive Learning-Based Transformer Model for Clustering, Interpreting, Visualizing, and Navigating Chemical Space (Journal article)

    Shrivastava, A. D., & Kell, D. B. (n.d.). FragNet, a Contrastive Learning-Based Transformer Model for Clustering, Interpreting, Visualizing, and Navigating Chemical Space. Molecules, 26(7), 2065. doi:10.3390/molecules26072065

    DOI: 10.3390/molecules26072065

    SARS-CoV-2 spike protein S1 induces fibrin(ogen) resistant to fibrinolysis: Implications for microclot formation in COVID-19 (Journal article)

    Grobbelaar, L. M., Venter, C., Vlok, M., Ngoepe, M., Laubscher, G. J., Lourens, P. J., . . . Pretorius, E. (n.d.). SARS-CoV-2 spike protein S1 induces fibrin(ogen) resistant to fibrinolysis: Implications for microclot formation in COVID-19. doi:10.1101/2021.03.05.21252960

    DOI: 10.1101/2021.03.05.21252960

    A palette of fluorophores that are differentially accumulated by wild-type and mutant strains of Escherichia coli: surrogate ligands for profiling bacterial membrane transporters. (Journal article)

    Salcedo-Sora, J. E., Jindal, S., O'Hagan, S., & Kell, D. B. (2021). A palette of fluorophores that are differentially accumulated by wild-type and mutant strains of Escherichia coli: surrogate ligands for profiling bacterial membrane transporters.. Microbiology (Reading, England), 167(2). doi:10.1099/mic.0.001016

    DOI: 10.1099/mic.0.001016

    2020

    Iron Dysregulation and Inflammagens Related to Oral and Gut Health Are Central to the Development of Parkinson's Disease (Journal article)

    Vuuren, M. J. V., Nell, T. A., Carr, J. A., Kell, D. B., & Pretorius, E. (2021). Iron Dysregulation and Inflammagens Related to Oral and Gut Health Are Central to the Development of Parkinson's Disease. BIOMOLECULES, 11(1). doi:10.3390/biom11010030

    DOI: 10.3390/biom11010030

    Automating Cloning by Natural Transformation (Journal article)

    Jiang, X., Palazzotto, E., Wybraniec, E., Munro, L. J., Zhang, H., Kell, D. B., . . . Lee, S. Y. (2020). Automating Cloning by Natural Transformation. ACS SYNTHETIC BIOLOGY, 9(12), 3228-3235. doi:10.1021/acssynbio.0c00240

    DOI: 10.1021/acssynbio.0c00240

    Deep learning and generative methods in cheminformatics and chemical biology: navigating small molecule space intelligently (Journal article)

    Kell, D. B., Samanta, S., & Swainston, N. (2020). Deep learning and generative methods in cheminformatics and chemical biology: navigating small molecule space intelligently. BIOCHEMICAL JOURNAL, 477(23), 4559-4580. doi:10.1042/BCJ20200781

    DOI: 10.1042/BCJ20200781

    Untargeted metabolomics of COVID-19 patient serum reveals potential prognostic markers of both severity and outcome (Journal article)

    Roberts, I., Muelas, M. W., Taylor, J. M., Davison, A. S., Xu, Y., Grixti, J. M., . . . Kell, D. B. (n.d.). Untargeted metabolomics of COVID-19 patient serum reveals potential prognostic markers of both severity and outcome. doi:10.1101/2020.12.09.20246389

    DOI: 10.1101/2020.12.09.20246389

    Detection of Citrullinated Fibrin in Plasma Clots of Rheumatoid Arthritis Patients and Its Relation to Altered Structural Clot Properties, Disease-Related Inflammation and Prothrombotic Tendency (Journal article)

    Bezuidenhout, J. A., Venter, C., Roberts, T. J., Tarr, G., Kell, D. B., & Pretorius, E. (2020). Detection of Citrullinated Fibrin in Plasma Clots of Rheumatoid Arthritis Patients and Its Relation to Altered Structural Clot Properties, Disease-Related Inflammation and Prothrombotic Tendency. FRONTIERS IN IMMUNOLOGY, 11. doi:10.3389/fimmu.2020.577523

    DOI: 10.3389/fimmu.2020.577523

    The biology of ergothioneine, an antioxidant nutraceutical (Journal article)

    Borodina, I., Kenny, L. C., McCarthy, C. M., Paramasivan, K., Pretorius, E., Roberts, T. J., . . . Kell, D. B. (2020). The biology of ergothioneine, an antioxidant nutraceutical. NUTRITION RESEARCH REVIEWS, 33(2), 190-217. doi:10.1017/S0954422419000301

    DOI: 10.1017/S0954422419000301

    Structural Similarities between Some Common Fluorophores Used in Biology, Marketed Drugs, Endogenous Metabolites, and Natural Products (Journal article)

    O'Hagan, S., & Kell, D. B. (2020). Structural Similarities between Some Common Fluorophores Used in Biology, Marketed Drugs, Endogenous Metabolites, and Natural Products. MARINE DRUGS, 18(11). doi:10.3390/md18110582

    DOI: 10.3390/md18110582

    Prevalence of readily detected amyloid blood clots in 'unclotted' Type 2 Diabetes Mellitus and COVID-19 plasma: a preliminary report (Journal article)

    Pretorius, E., Venter, C., Laubscher, G. J., Lourens, P. J., Steenkamp, J., & Kell, D. B. (2020). Prevalence of readily detected amyloid blood clots in 'unclotted' Type 2 Diabetes Mellitus and COVID-19 plasma: a preliminary report. Cardiovascular Diabetology, 19(1). doi:10.1186/s12933-020-01165-7

    DOI: 10.1186/s12933-020-01165-7

    Bacteria, Lipopolysaccharides, Amyloid and the Role of Iron Dysregulation in Parkinson’s Disease (Journal article)

    Vuuren, M. J. V., Nell, T. A., Carr, J. A., Kell, D., & Pretorius, E. (2020). Bacteria, Lipopolysaccharides, Amyloid and the Role of Iron Dysregulation in Parkinson’s Disease. doi:10.20944/preprints202011.0380.v1

    DOI: 10.20944/preprints202011.0380.v1

    Erythrocyte, Platelet, Serum Ferritin, and P-Selectin Pathophysiology Implicated in Severe Hypercoagulation and Vascular Complications in COVID-19 (Journal article)

    Venter, C., Bezuidenhout, J. A., Laubscher, G. J., Lourens, P. J., Steenkamp, J., Kell, D. B., & Pretorius, E. (2020). Erythrocyte, Platelet, Serum Ferritin, and P-Selectin Pathophysiology Implicated in Severe Hypercoagulation and Vascular Complications in COVID-19. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 21(21). doi:10.3390/ijms21218234

    DOI: 10.3390/ijms21218234

    IsPorphyromonas gingivalisinvolved in Parkinson's disease? (Journal article)

    Olsen, I., Kell, D. B., & Pretorius, E. (2020). IsPorphyromonas gingivalisinvolved in Parkinson's disease?. EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES, 39(11), 2013-2018. doi:10.1007/s10096-020-03944-2

    DOI: 10.1007/s10096-020-03944-2

    An untargeted metabolomics strategy to measure differences in metabolite uptake and excretion by mammalian cell lines (Journal article)

    Muelas, M. W., Roberts, I., Mughal, F., O'Hagan, S., Day, P. J., & Kell, D. B. (2020). An untargeted metabolomics strategy to measure differences in metabolite uptake and excretion by mammalian cell lines. METABOLOMICS, 16(10). doi:10.1007/s11306-020-01725-8

    DOI: 10.1007/s11306-020-01725-8

    DeepGraphMolGen, a multi-objective, computational strategy for generating molecules with desirable properties: a graph convolution and reinforcement learning approach (Journal article)

    Khemchandani, Y., O'Hagan, S., Samanta, S., Swainston, N., Roberts, T. J., Bollegala, D., & Kell, D. B. (2020). DeepGraphMolGen, a multi-objective, computational strategy for generating molecules with desirable properties: a graph convolution and reinforcement learning approach. Journal of Cheminformatics, 12(1). doi:10.1186/s13321-020-00454-3

    DOI: 10.1186/s13321-020-00454-3

    A Quantitative Survey of Bacterial Persistence in the Presence of Antibiotics: Towards Antipersister Antimicrobial Discovery (Journal article)

    Salcedo-Sora, J. E., & Kell, D. B. (2020). A Quantitative Survey of Bacterial Persistence in the Presence of Antibiotics: Towards Antipersister Antimicrobial Discovery. ANTIBIOTICS-BASEL, 9(8). doi:10.3390/antibiotics9080508

    DOI: 10.3390/antibiotics9080508

    SBML Level 3: an extensible format for the exchange and reuse of biological models (Journal article)

    Keating, S. M., Waltemath, D., Koenig, M., Zhang, F., Draeger, A., Chaouiya, C., . . . Members, S. B. M. L. L. 3. C. (2020). SBML Level 3: an extensible format for the exchange and reuse of biological models. MOLECULAR SYSTEMS BIOLOGY, 16(8). Retrieved from http://gateway.webofknowledge.com/

    DeepGraphMolGen, a multi-objective, computational strategy for generating molecules with desirable properties: a graph convolution and reinforcement learning approach (Journal article)

    Khemchandani, Y., O'Hagan, S., Samanta, S., Swainston, N., Roberts, T., Bollegala, D., & Kell, D. (2020). DeepGraphMolGen, a multi-objective, computational strategy for generating molecules with desirable properties: a graph convolution and reinforcement learning approach. doi:10.21203/rs.3.rs-32446/v2

    DOI: 10.21203/rs.3.rs-32446/v2

    Prevalence of amyloid blood clots in COVID-19 plasma (Journal article)

    Pretorius, E., Venter, C., Laubscher, G. J., Lourens, P. J., Steenkamp, J., & Kell, D. (2020). Prevalence of amyloid blood clots in COVID-19 plasma. doi:10.1101/2020.07.28.20163543

    DOI: 10.1101/2020.07.28.20163543

    VAE-Sim: A Novel Molecular Similarity Measure Based on a Variational Autoencoder. (Journal article)

    Samanta, S., O'Hagan, S., Swainston, N., Roberts, T. J., & Kell, D. B. (2020). VAE-Sim: A Novel Molecular Similarity Measure Based on a Variational Autoencoder.. Molecules, 25(15). doi:10.3390/molecules25153446

    DOI: 10.3390/molecules25153446

    Gingipain R1 and Lipopolysaccharide From Porphyromonas gingivalis Have Major Effects on Blood Clot Morphology and Mechanics (Journal article)

    Nunes, J. M., Fillis, T., Page, M. J., Venter, C., Lancry, O., Kell, D. B., . . . Pretorius, E. (2020). Gingipain R1 and Lipopolysaccharide FromPorphyromonas gingivalisHave Major Effects on Blood Clot Morphology and Mechanics. FRONTIERS IN IMMUNOLOGY, 11. doi:10.3389/fimmu.2020.01551

    DOI: 10.3389/fimmu.2020.01551

    Covid-19: The Rollercoaster of Fibrin(Ogen), D-Dimer, Von Willebrand Factor, P-Selectin and Their Interactions with Endothelial Cells, Platelets and Erythrocytes (Journal article)

    Grobler, C., Maphumulo, S. C., Grobbelaar, L. M., Bredenkamp, J. C., Laubscher, G. J., Lourens, P. J., . . . Pretorius, E. (2020). Covid-19: The Rollercoaster of Fibrin(Ogen), D-Dimer, Von Willebrand Factor, P-Selectin and Their Interactions with Endothelial Cells, Platelets and Erythrocytes. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 21(14). doi:10.3390/ijms21145168

    DOI: 10.3390/ijms21145168

    COVID-19: The Rollercoaster of Fibrin(ogen), D-dimer, von Willebrand Factor, P-selectin and Their Interactions with Endothelial Cells, Platelets and Erythrocytes (Journal article)

    Grobler, C., Bredenkamp, J., Grobbelaar, M., Maphumulo, S., Laubscher, J., Steenkamp, J., . . . Pretorius, E. (2020). COVID-19: The Rollercoaster of Fibrin(ogen), D-dimer, von Willebrand Factor, P-selectin and Their Interactions with Endothelial Cells, Platelets and Erythrocytes. doi:10.20944/preprints202007.0142.v1

    DOI: 10.20944/preprints202007.0142.v1

    The RESOLUTE consortium: unlocking SLC transporters for drug discovery (Journal article)

    Superti-Furga, G., Lackner, D., Wiedmer, T., Ingles-Prieto, A., Steppan, C. M., & Consortium, R. E. S. O. L. U. T. E. (2020). The RESOLUTE consortium: unlocking SLC transporters for drug discovery. NATURE REVIEWS DRUG DISCOVERY, 19(7), 429-430. doi:10.1038/d41573-020-00056-6

    DOI: 10.1038/d41573-020-00056-6

    VAE-Sim: a novel molecular similarity measure based on a variational autoencoder (Journal article)

    Samanta, S., O’Hagan, S., Swainston, N., Roberts, T., & Kell, D. (2020). VAE-Sim: a novel molecular similarity measure based on a variational autoencoder. doi:10.1101/2020.06.26.172908

    DOI: 10.1101/2020.06.26.172908

    A palette of fluorophores that are differentially accumulated by wild-type and mutant strains of Escherichia coli: surrogate ligands for bacterial membrane transporters (Journal article)

    Salcedo-Sora, J. E., Jindal, S., O’Hagan, S., & Kell, D. (2020). A palette of fluorophores that are differentially accumulated by wild-type and mutant strains of Escherichia coli: surrogate ligands for bacterial membrane transporters. doi:10.1101/2020.06.15.152629

    DOI: 10.1101/2020.06.15.152629

    DeepGraphMol, a multi-objective, computational strategy for generating molecules with desirable properties: a graph convolution and reinforcement learning approach (Journal article)

    Khemchandani, Y., O'Hagan, S., Samanta, S., Swainston, N., Roberts, T., Bollegala, D., & Kell, D. (2020). DeepGraphMol, a multi-objective, computational strategy for generating molecules with desirable properties: a graph convolution and reinforcement learning approach. doi:10.21203/rs.3.rs-32446/v1

    DOI: 10.21203/rs.3.rs-32446/v1

    An untargeted metabolomics strategy to measure differences in metabolite uptake and excretion by mammalian cell lines (Journal article)

    Muelas, M. W., Roberts, I., Mughal, F., O’Hagan, S., Day, P., & Kell, D. (2020). An untargeted metabolomics strategy to measure differences in metabolite uptake and excretion by mammalian cell lines. doi:10.1101/2020.06.02.129239

    DOI: 10.1101/2020.06.02.129239

    Author Correction: Hitchhiking into the cell. (Journal article)

    Kell, D. B. (2020). Author Correction: Hitchhiking into the cell.. Nature chemical biology, 16(6), 710. doi:10.1038/s41589-020-0540-y

    DOI: 10.1038/s41589-020-0540-y

    The Atypical Fibrin Fibre Network in Rheumatoid Arthritis and its Relation to Autoimmunity, Inflammation and Thrombosis (Journal article)

    Bezuidenhout, J., Venter, C., Roberts, T., Tarr, G., Kell, D., & Pretorius, E. (2020). The Atypical Fibrin Fibre Network in Rheumatoid Arthritis and its Relation to Autoimmunity, Inflammation and Thrombosis. doi:10.1101/2020.05.28.121301

    DOI: 10.1101/2020.05.28.121301

    The Biology of Lactoferrin, an Iron-Binding Protein That Can Help Defend Against Viruses and Bacteria (Journal article)

    Kell, D. B., Heyden, E. L., & Pretorius, E. (2020). The Biology of Lactoferrin, an Iron-Binding Protein That Can Help Defend Against Viruses and Bacteria. Frontiers in Immunology, 11. doi:10.3389/fimmu.2020.01221

    DOI: 10.3389/fimmu.2020.01221

    DeepGraphMol, a multi-objective, computational strategy for generating molecules with desirable properties: a graph convolution and reinforcement learning approach (Journal article)

    Khemchandani, Y., O’Hagan, S., Samanta, S., Swainston, N., Roberts, T., Bollegala, D., & Kell, D. (2020). DeepGraphMol, a multi-objective, computational strategy for generating molecules with desirable properties: a graph convolution and reinforcement learning approach. doi:10.1101/2020.05.25.114165

    DOI: 10.1101/2020.05.25.114165

    Hitchhiking into the cell (Journal article)

    Kell, D. B. (2020). Hitchhiking into the cell. NATURE CHEMICAL BIOLOGY, 16(4), 367-368. doi:10.1038/s41589-020-0489-x

    DOI: 10.1038/s41589-020-0489-x

    Effect of L-Ergothioneine on the metabolic plasma profile of the RUPP rat model of pre-eclampsia (Journal article)

    Morillon, A. -C., Williamson, R. D., Baker, P. N., Kell, D. B., Kenny, L. C., English, J. A., . . . McCarthy, C. (2020). Effect of L-Ergothioneine on the metabolic plasma profile of the RUPP rat model of pre-eclampsia. PLOS ONE, 15(3). doi:10.1371/journal.pone.0230977

    DOI: 10.1371/journal.pone.0230977

    Why most transporter mutations that cause antibiotic resistance are to efflux pumps rather than to import transporters (Journal article)

    Mendes, P., Girardi, E., Superti-Furga, G., & Kell, D. (2020). Why most transporter mutations that cause antibiotic resistance are to efflux pumps rather than to import transporters. doi:10.1101/2020.01.16.909507

    DOI: 10.1101/2020.01.16.909507

    L-(+)-Ergothioneine Significantly Improves the Clinical Characteristics of Preeclampsia in the Reduced Uterine Perfusion Pressure Rat Model (Journal article)

    Williamson, R. D., McCarthy, F. P., Manna, S., Groarke, E., Kell, D. B., Kenny, L. C., & McCarthy, C. M. (2020). L-(+)-Ergothioneine Significantly Improves the Clinical Characteristics of Preeclampsia in the Reduced Uterine Perfusion Pressure Rat Model. HYPERTENSION, 75(2), 561-568. doi:10.1161/HYPERTENSIONAHA.119.13929

    DOI: 10.1161/HYPERTENSIONAHA.119.13929

    2019

    The role and robustness of the Gini coefficient as an unbiased tool for the selection of Gini genes for normalising expression profiling data (Journal article)

    Muelas, M. W., Mughal, F., O'Hagan, S., Day, P. J., & Kell, D. B. (2019). The role and robustness of the Gini coefficient as an unbiased tool for the selection of Gini genes for normalising expression profiling data. SCIENTIFIC REPORTS, 9. doi:10.1038/s41598-019-54288-7

    DOI: 10.1038/s41598-019-54288-7

    A Possible Role of Amyloidogenic Blood Clotting in the Evolving Haemodynamics of Female Migraine-With-Aura: Results From a Pilot Study (Journal article)

    Kell, D. (2019). A Possible Role of Amyloidogenic Blood Clotting in the Evolving Haemodynamics of Female Migraine-With-Aura: Results From a Pilot Study. Frontiers in Neurology. doi:10.3389/fneur.2019.01262

    DOI: 10.3389/fneur.2019.01262

    Structural similarities between some common fluorophores used in biology and marketed drugs, endogenous metabolites, and natural products (Journal article)

    O’Hagan, S., & Kell, D. (2019). Structural similarities between some common fluorophores used in biology and marketed drugs, endogenous metabolites, and natural products. doi:10.1101/834325

    DOI: 10.1101/834325

    Engineering the Yeast Saccharomyces cerevisiae for the Production of L-(+)-Ergothioneine (Journal article)

    van der Hoek, S. A., Darbani, B., Zugaj, K. E., Prabhala, B. K., Biron, M. B., Randelovic, M., . . . Borodina, I. (2019). Engineering the Yeast Saccharomyces cerevisiae for the Production of L-(+)-Ergothioneine. FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY, 7. doi:10.3389/fbioe.2019.00262

    DOI: 10.3389/fbioe.2019.00262

    A top priority in pre-eclampsia research: development of a reliable and inexpensive urinary screening test. (Journal article)

    Scioscia, M., Dekker, G. A., Chaouat, G., Dawonauth, L., Dechend, R., Goldman-Wohl, D., . . . Robillard, P. -Y. (2019). A top priority in pre-eclampsia research: development of a reliable and inexpensive urinary screening test.. The Lancet. Global health, 7(10), e1312-e1313. doi:10.1016/s2214-109x(19)30319-5

    DOI: 10.1016/s2214-109x(19)30319-5

    Erythrocyte health and the possible role of amyloidogenic blood clotting in the evolving haemodynamics of female migraine-with-aura pathophysiology: Results from a pilot study (Conference Paper)

    de Villiers, S., Bester, J., Kell, D. B., & Pretorius, E. (2019). Erythrocyte health and the possible role of amyloidogenic blood clotting in the evolving haemodynamics of female migraine-with-aura pathophysiology: Results from a pilot study. In CEPHALALGIA Vol. 39 (pp. 150-151). Retrieved from http://gateway.webofknowledge.com/

    Parkinson’s disease: a systemic inflammatory disease accompanied by bacterial inflammagens (Journal article)

    Adams, B., Nunes, M., Page, M., Roberts, T., Carr, J., Nell, T., . . . Pretorius, E. (2019). Parkinson’s disease: a systemic inflammatory disease accompanied by bacterial inflammagens. Frontiers in Aging Neuroscience. doi:10.3389/fnagi.2019.00210

    DOI: 10.3389/fnagi.2019.00210

    Involvement of multiple influx and efflux transporters in the accumulation of cationic fluorescent dyes by Escherichia coli (Journal article)

    Jindal, S., Yang, L., Day, P. J., & Kell, D. B. (2019). Involvement of multiple influx and efflux transporters in the accumulation of cationic fluorescent dyes by Escherichia coli. BMC MICROBIOLOGY, 19. doi:10.1186/s12866-019-1561-0

    DOI: 10.1186/s12866-019-1561-0

    A brain-permeable inhibitor of the neurodegenerative disease target kynurenine 3-monooxygenase prevents accumulation of neurotoxic metabolites (Journal article)

    Zhang, S., Sakuma, M., Deora, G. S., Levy, C. W., Klausing, A., Breda, C., . . . Scrutton, N. S. (2019). A brain-permeable inhibitor of the neurodegenerative disease target kynurenine 3-monooxygenase prevents accumulation of neurotoxic metabolites. COMMUNICATIONS BIOLOGY, 2. doi:10.1038/s42003-019-0520-5

    DOI: 10.1038/s42003-019-0520-5

    GeneORator: An Effective Strategy for Navigating Protein Sequence Space More Efficiently through Boolean OR-Type DNA Libraries (Journal article)

    Currin, A., Kwok, J., Sadler, J. C., Bell, E. L., Swainston, N., Ababi, M., . . . Kell, D. B. (2019). GeneORator: An Effective Strategy for Navigating Protein Sequence Space More Efficiently through Boolean OR-Type DNA Libraries. ACS SYNTHETIC BIOLOGY, 8(6), 1371-1378. doi:10.1021/acssynbio.9b00063

    DOI: 10.1021/acssynbio.9b00063

    Involvement of multiple influx and efflux transporters in the accumulation of cationic fluorescent dyes byEscherichia coli (Journal article)

    Jindal, S., Yang, L., Day, P., & Kell, D. (2019). Involvement of multiple influx and efflux transporters in the accumulation of cationic fluorescent dyes byEscherichia coli. doi:10.1101/603688

    DOI: 10.1101/603688

    Very rapid flow cytometric assessment of antimicrobial susceptibility during the apparent lag phase of microbial (re)growth. (Journal article)

    Jindal, S., Thampy, H., Day, P. J. R., & Kell, D. B. (2019). Very rapid flow cytometric assessment of antimicrobial susceptibility during the apparent lag phase of microbial (re)growth.. Microbiology, 165(4), 439-454. doi:10.1099/mic.0.000777

    DOI: 10.1099/mic.0.000777

    Serum amyloid A binds to fibrin(ogen), promoting fibrin amyloid formation (Journal article)

    Page, M. J., Thomson, G. J. A., Nunes, J. M., Engelbrecht, A. -M., Nell, T. A., de Villiers, W. J. S., . . . Pretorius, E. (2019). Serum amyloid A binds to fibrin(ogen), promoting fibrin amyloid formation. SCIENTIFIC REPORTS, 9. doi:10.1038/s41598-019-39056-x

    DOI: 10.1038/s41598-019-39056-x

    Bacterial Dysbiosis and Translocation in Psoriasis Vulgaris (Journal article)

    Visser, M. J. E., Kell, D. B., & Pretorius, E. (2019). Bacterial Dysbiosis and Translocation in Psoriasis Vulgaris. FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY, 9. doi:10.3389/fcimb.2019.00007

    DOI: 10.3389/fcimb.2019.00007

    2018

    An automated Design-Build-Test-Learn pipeline for enhanced microbial production of fine chemicals (Journal article)

    Carbonell, P., Jervis, A. J., Robinson, C. J., Yan, C., Dunstan, M., Swainston, N., . . . Scrutton, N. S. (2018). An automated Design-Build-Test-Learn pipeline for enhanced microbial production of fine chemicals. COMMUNICATIONS BIOLOGY, 1. doi:10.1038/s42003-018-0076-9

    DOI: 10.1038/s42003-018-0076-9

    Iron Dysregulation and Dormant Microbes as Causative Agents for Impaired Blood Rheology and Pathological Clotting in Alzheimer's Type Dementia (Journal article)

    Pretorius, L., Kell, D. B., & Pretorius, E. (2018). Iron Dysregulation and Dormant Microbes as Causative Agents for Impaired Blood Rheology and Pathological Clotting in Alzheimer's Type Dementia. FRONTIERS IN NEUROSCIENCE, 12. doi:10.3389/fnins.2018.00851

    DOI: 10.3389/fnins.2018.00851

    Correlative Light-Electron Microscopy detects lipopolysaccharide and its association with fibrin fibres in Parkinson's Disease, Alzheimer's Disease and Type 2 Diabetes Mellitus (Journal article)

    de Waal, G. M., Engelbrecht, L., Davis, T., de Villiers, W. J. S., Kell, D. B., & Pretorius, E. (2018). Correlative Light-Electron Microscopy detects lipopolysaccharide and its association with fibrin fibres in Parkinson's Disease, Alzheimer's Disease and Type 2 Diabetes Mellitus. SCIENTIFIC REPORTS, 8. doi:10.1038/s41598-018-35009-y

    DOI: 10.1038/s41598-018-35009-y

    Ultra-high throughput functional enrichment of large monoamine oxidase (MAO-N) libraries by fluorescence activated cell sorting (Journal article)

    Sadler, J. C., Currin, A., & Kell, D. B. (2018). Ultra-high throughput functional enrichment of large monoamine oxidase (MAO-N) libraries by fluorescence activated cell sorting. ANALYST, 143(19), 4747-4755. doi:10.1039/c8an00851e

    DOI: 10.1039/c8an00851e

    The Potential of LPS-Binding Protein to Reverse Amyloid Formation in Plasma Fibrin of Individuals With Alzheimer-Type Dementia (Journal article)

    Pretorius, E., Bester, J., Page, M. J., & Kell, D. B. (2018). The Potential of LPS-Binding Protein to Reverse Amyloid Formation in Plasma Fibrin of Individuals With Alzheimer-Type Dementia. FRONTIERS IN AGING NEUROSCIENCE, 10. doi:10.3389/fnagi.2018.00257

    DOI: 10.3389/fnagi.2018.00257

    No effects without causes: the Iron Dysregulation and Dormant Microbes hypothesis for chronic, inflammatory diseases (Journal article)

    Kell, D. B., & Pretorius, E. (2018). No effects without causes: the Iron Dysregulation and Dormant Microbes hypothesis for chronic, inflammatory diseases. BIOLOGICAL REVIEWS, 93(3), 1518-1557. doi:10.1111/brv.12407

    DOI: 10.1111/brv.12407

    PartsGenie: an integrated tool for optimizing and sharing synthetic biology parts (Journal article)

    Swainston, N., Dunstan, M., Jervis, A. J., Robinson, C. J., Carbonell, P., Williams, A. R., . . . Kell, D. B. (2018). PartsGenie: an integrated tool for optimizing and sharing synthetic biology parts. Bioinformatics, 34(13), 2327-2329. doi:10.1093/bioinformatics/bty105

    DOI: 10.1093/bioinformatics/bty105

    Selenzyme: enzyme selection tool for pathway design (Journal article)

    Carbonell, P., Wong, J., Swainston, N., Takano, E., Turner, N. J., Scrutton, N. S., . . . Faulon, J. -L. (2018). Selenzyme: enzyme selection tool for pathway design. BIOINFORMATICS, 34(12), 2153-2154. doi:10.1093/bioinformatics/bty065

    DOI: 10.1093/bioinformatics/bty065

    Energetic evolution of cellular Transportomes (Journal article)

    Darbani, B., Kell, D. B., & Borodina, I. (2018). Energetic evolution of cellular Transportomes. BMC GENOMICS, 19. doi:10.1186/s12864-018-4816-5

    DOI: 10.1186/s12864-018-4816-5

    To What Extent Are the Terminal Stages of Sepsis, Septic Shock, Systemic Inflammatory Response Syndrome, and Multiple Organ Dysfunction Syndrome Actually Driven by a Prion/Amyloid Form of Fibrin? (Journal article)

    Kell, D. B., & Pretorius, E. (2018). To What Extent Are the Terminal Stages of Sepsis, Septic Shock, Systemic Inflammatory Response Syndrome, and Multiple Organ Dysfunction Syndrome Actually Driven by a Prion/Amyloid Form of Fibrin?. SEMINARS IN THROMBOSIS AND HEMOSTASIS, 44(3), 224-238. doi:10.1055/s-0037-1604108

    DOI: 10.1055/s-0037-1604108

    Engineering the "Missing Link" in Biosynthetic (-)-Menthol Production: Bacterial Isopulegone Isomerase (Journal article)

    Currin, A., Dunstan, M. S., Johannissen, L. O., Hollywood, K. A., Vinaixa, M., Jervis, A. J., . . . Scrutton, N. S. (2018). Engineering the "Missing Link" in Biosynthetic (-)-Menthol Production: Bacterial Isopulegone Isomerase. ACS CATALYSIS, 8(3), 2012-2020. doi:10.1021/acscatal.7b04115

    DOI: 10.1021/acscatal.7b04115

    Lipopolysaccharide-binding protein (LBP) can reverse the amyloid state of fibrin seen or induced in Parkinson's disease (Journal article)

    Pretorius, E., Page, M. J., Mbotwe, S., & Kell, D. B. (2018). Lipopolysaccharide-binding protein (LBP) can reverse the amyloid state of fibrin seen or induced in Parkinson's disease. PLOS ONE, 13(3). doi:10.1371/journal.pone.0192121

    DOI: 10.1371/journal.pone.0192121

    The potential therapeutic effects of ergothioneine in pre-eclampsia (Journal article)

    Kerley, R. N., McCarthy, C., Kell, D. B., & Kenny, L. C. (2018). The potential therapeutic effects of ergothioneine in pre-eclampsia. FREE RADICAL BIOLOGY AND MEDICINE, 117, 145-157. doi:10.1016/j.freeradbiomed.2017.12.030

    DOI: 10.1016/j.freeradbiomed.2017.12.030

    GeneGini: Assessment via the Gini Coefficient of Reference “Housekeeping” Genes and Diverse Human Transporter Expression Profiles (Journal article)

    O'Hagan, S., Muelas, M. W., Day, P. J., Lundberg, E., & Kell, D. B. (2018). GeneGini: Assessment via the Gini Coefficient of Reference “Housekeeping” Genes and Diverse Human Transporter Expression Profiles. Cell Systems, 6(2), 230-244.E1. doi:10.1016/j.cels.2018.01.003

    DOI: 10.1016/j.cels.2018.01.003

    Immunological Tolerance, Pregnancy, and Preeclampsia: The Roles of Semen Microbes and the Father (Journal article)

    Kenny, L. C., & Kell, D. B. (2018). Immunological Tolerance, Pregnancy, and Preeclampsia: The Roles of Semen Microbes and the Father. FRONTIERS IN MEDICINE, 4. doi:10.3389/fmed.2017.00239

    DOI: 10.3389/fmed.2017.00239

    Analysing and Navigating Natural Products Space for Generating Small, Diverse, But Representative Chemical Libraries (Journal article)

    O'Hagan, S., & Kell, D. B. (2018). Analysing and Navigating Natural Products Space for Generating Small, Diverse, But Representative Chemical Libraries. BIOTECHNOLOGY JOURNAL, 13(1). doi:10.1002/biot.201700503

    DOI: 10.1002/biot.201700503

    Both lipopolysaccharide and lipoteichoic acids potently induce anomalous fibrin amyloid formation: assessment with novel Amytracker (TM) stains (Journal article)

    Pretorius, E., Page, M. J., Hendricks, L., Nkosi, N. B., Benson, S. R., & Kell, D. B. (2018). Both lipopolysaccharide and lipoteichoic acids potently induce anomalous fibrin amyloid formation: assessment with novel Amytracker (TM) stains. JOURNAL OF THE ROYAL SOCIETY INTERFACE, 15(139). doi:10.1098/rsif.2017.0941

    DOI: 10.1098/rsif.2017.0941

    Fast and Flexible Synthesis of Combinatorial Libraries for Directed Evolution (Chapter)

    Sadler, J. C., Green, L., Swainston, N., Kell, D. B., & Currin, A. (2018). Fast and Flexible Synthesis of Combinatorial Libraries for Directed Evolution. In ENZYMES IN SYNTHETIC BIOLOGY (Vol. 608, pp. 59-79). doi:10.1016/bs.mie.2018.04.006

    DOI: 10.1016/bs.mie.2018.04.006

    Microcompartmentation (Chapter)

    Jones, D. P. (n.d.). Microcompartmentation. CRC Press. doi:10.1201/9781351074575

    DOI: 10.1201/9781351074575

    2017

    Substantial fibrin amyloidogenesis in type 2 diabetes assessed using amyloid-selective fluorescent stains (Journal article)

    Pretorius, E., Page, M. J., Engelbrecht, L., Ellis, G. C., & Kell, D. B. (2017). Substantial fibrin amyloidogenesis in type 2 diabetes assessed using amyloid-selective fluorescent stains. CARDIOVASCULAR DIABETOLOGY, 16. doi:10.1186/s12933-017-0624-5

    DOI: 10.1186/s12933-017-0624-5

    Immunological tolerance, pregnancy and pre-eclampsia: the roles of semen microbes and the father1 (Journal article)

    Kenny, L., & Kell, D. (2017). Immunological tolerance, pregnancy and pre-eclampsia: the roles of semen microbes and the father1. doi:10.1101/198796

    DOI: 10.1101/198796

    PartsGenie: an integrated tool for optimising and sharing synthetic biology parts (Journal article)

    Swainston, N., Dunstan, M., Jervis, A., Robinson, C., Carbonell, P., Williams, A., . . . Kell, D. (2017). PartsGenie: an integrated tool for optimising and sharing synthetic biology parts. doi:10.1101/189357

    DOI: 10.1101/189357

    Selenzyme: Enzyme selection tool for pathway design (Journal article)

    Carbonell, P., Wong, J., Swainston, N., Takano, E., Turner, N., Scrutton, N., . . . Faulon, J. -L. (2017). Selenzyme: Enzyme selection tool for pathway design. doi:10.1101/188979

    DOI: 10.1101/188979

    A Metabolic Reaction Balancing Web Service for Computational Systems Biology (Journal article)

    Dobson, P., Mendes, P., Kell, D., & Swainston, N. (2017). A Metabolic Reaction Balancing Web Service for Computational Systems Biology. doi:10.1101/187328

    DOI: 10.1101/187328

    Evolutionary algorithms and synthetic biology for directed evolution: commentary on "on the mapping of genotype to phenotype in evolutionary algorithms" by Peter A. Whigham, Grant Dick, and James Maclaurin (Journal article)

    Kell, D. B. (2017). Evolutionary algorithms and synthetic biology for directed evolution: commentary on "on the mapping of genotype to phenotype in evolutionary algorithms" by Peter A. Whigham, Grant Dick, and James Maclaurin. GENETIC PROGRAMMING AND EVOLVABLE MACHINES, 18(3), 373-378. doi:10.1007/s10710-017-9292-1

    DOI: 10.1007/s10710-017-9292-1

    Lipopolysaccharide-binding protein (LBP) reverses the amyloid state of fibrin seen in plasma of type 2 diabetics with cardiovascular co-morbidities (Journal article)

    Pretorius, E., Mbotwe, S., & Kell, D. B. (2017). Lipopolysaccharide-binding protein (LBP) reverses the amyloid state of fibrin seen in plasma of type 2 diabetics with cardiovascular co-morbidities. SCIENTIFIC REPORTS, 7. doi:10.1038/s41598-017-09860-4

    DOI: 10.1038/s41598-017-09860-4

    Stability in metabolic phenotypes and inferred metagenome profiles before the onset of colitis-induced inflammation (Journal article)

    Glymenaki, M., Barnes, A., Hagan, S. O., Warhurst, G., McBain, A. J., Wilson, I. D., . . . Cruickshank, S. M. (2017). Stability in metabolic phenotypes and inferred metagenome profiles before the onset of colitis-induced inflammation. SCIENTIFIC REPORTS, 7. doi:10.1038/s41598-017-08732-1

    DOI: 10.1038/s41598-017-08732-1

    biochem4j: Integrated and extensible biochemical knowledge through graph databases (Journal article)

    Swainston, N., Batista-Navarro, R., Carbonell, P., Dobson, P. D., Dunstan, M., Jervis, A. J., . . . Breitling, R. (n.d.). biochem4j: Integrated and extensible biochemical knowledge through graph databases. PLOS ONE, 12(7). doi:10.1371/journal.pone.0179130

    DOI: 10.1371/journal.pone.0179130

    CodonGenie: optimised ambiguous codon design tools (Journal article)

    Swainston, N., Currin, A., Green, L., Breitling, R., Day, P. J., & Kell, D. B. (2017). CodonGenie: optimised ambiguous codon design tools. PEERJ COMPUTER SCIENCE. doi:10.7717/peerj-cs.120

    DOI: 10.7717/peerj-cs.120

    Mass spectrometry imaging shows major derangements in neurogranin and in purine metabolism in the triple-knockout 3 x Tg Alzheimer mouse model (Journal article)

    Esteve, C., Jones, E. A., Kell, D. B., Boutin, H., & McDonnell, L. A. (2017). Mass spectrometry imaging shows major derangements in neurogranin and in purine metabolism in the triple-knockout 3 x Tg Alzheimer mouse model. BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS, 1865(7), 747-754. doi:10.1016/j.bbapap.2017.04.002

    DOI: 10.1016/j.bbapap.2017.04.002

    Novel ‘housekeeping’ genes and an unusually heterogeneous distribution of transporter expression profiles in human tissues and cell lines, assessed using the Gini coefficient (Journal article)

    O’Hagan, S., Muelas, M. W., Day, P., Lundberg, E., & Kell, D. (2017). Novel ‘housekeeping’ genes and an unusually heterogeneous distribution of transporter expression profiles in human tissues and cell lines, assessed using the Gini coefficient. doi:10.1101/155697

    DOI: 10.1101/155697

    Both lipopolysaccharide and lipoteichoic acids potently induce anomalous fibrin amyloid formation: assessment with novel Amytracker™stains (Journal article)

    Pretorius, E., Page, M., Hendricks, L., Nkosi, N., Benson, S., & Kell, D. (2017). Both lipopolysaccharide and lipoteichoic acids potently induce anomalous fibrin amyloid formation: assessment with novel Amytracker™stains. doi:10.1101/143867

    DOI: 10.1101/143867

    Commentary on "Rapid identification of Streptococcus and Enterococcus species using diffuse reflectance-absorbance Fourier transform infrared spectroscopy and artificial neural networks" (Journal article)

    Goodacre, R., & Kell, D. B. (2017). Commentary on "Rapid identification of Streptococcus and Enterococcus species using diffuse reflectance-absorbance Fourier transform infrared spectroscopy and artificial neural networks". FEMS MICROBIOLOGY LETTERS, 364(10). doi:10.1093/femsle/fnx018

    DOI: 10.1093/femsle/fnx018

    Lipopolysaccharide-binding protein (LBP) can reverse the amyloid state of fibrin seen or induced in Parkinson’s disease: implications for its aetiology (Journal article)

    Pretorius, E., Mbotwe, S., & Kell, D. (2017). Lipopolysaccharide-binding protein (LBP) can reverse the amyloid state of fibrin seen or induced in Parkinson’s disease: implications for its aetiology. doi:10.1101/124180

    DOI: 10.1101/124180

    Enhancing Drug Efficacy and Therapeutic Index through Cheminformatics-Based Selection of Small Molecule Binary Weapons That Improve Transporter-Mediated Targeting: A Cytotoxicity System Based on Gemcitabine (Journal article)

    Grixti, J. M., O'Hagan, S., Day, P. J., & Kell, D. B. (2017). Enhancing Drug Efficacy and Therapeutic Index through Cheminformatics-Based Selection of Small Molecule Binary Weapons That Improve Transporter-Mediated Targeting: A Cytotoxicity System Based on Gemcitabine. FRONTIERS IN PHARMACOLOGY, 8. doi:10.3389/fphar.2017.00155

    DOI: 10.3389/fphar.2017.00155

    A bacterial component to Alzheimer's-type dementia seen via a systems biology approach that links iron dysregulation and inflammagen shedding to disease (Chapter)

    Pretorius, E., Bester, J., & Kell, D. B. (2017). A bacterial component to Alzheimer's-type dementia seen via a systems biology approach that links iron dysregulation and inflammagen shedding to disease. In Handbook of Infection and Alzheimer's Disease (pp. 313-332). doi:10.3233/978-1-61499-706-313

    DOI: 10.3233/978-1-61499-706-313

    Microbes and Alzheimer's disease (Chapter)

    Itzhaki, R. F., Lathe, R., Balin, B. J., Ball, M. J., Bearere, E. L., Braak, H., . . . Whittum-Hudson, J. A. (2017). Microbes and Alzheimer's disease. In Handbook of Infection and Alzheimer's Disease (pp. 3-8). doi:10.3233/978-1-61499-706-3

    DOI: 10.3233/978-1-61499-706-3

    Analysis of drug-endogenous human metabolite similarities in terms of their maximum common substructures (Journal article)

    O'Hagan, S., & Kell, D. B. (2017). Analysis of drug-endogenous human metabolite similarities in terms of their maximum common substructures. JOURNAL OF CHEMINFORMATICS, 9. doi:10.1186/s13321-017-0198-y

    DOI: 10.1186/s13321-017-0198-y

    Computing exponentially faster: implementing a non- deterministic universal Turing machine using DNA (Journal article)

    Currin, A., Korovin, K., Ababi, M., Roper, K., Kell, D. B., Day, P. J., & King, R. D. (2017). Computing exponentially faster: implementing a non- deterministic universal Turing machine using DNA. JOURNAL OF THE ROYAL SOCIETY INTERFACE, 14(128). doi:10.1098/rsif.2016.0990

    DOI: 10.1098/rsif.2016.0990

    Consensus rank orderings of molecular fingerprints illustrate the ‘most genuine’ similarities between marketed drugs and small endogenous human metabolites, but highlight exogenous natural products as the most important ‘natural’ drug transporter substrates (Journal article)

    O’Hagan, S., & Kell, D. (2017). Consensus rank orderings of molecular fingerprints illustrate the ‘most genuine’ similarities between marketed drugs and small endogenous human metabolites, but highlight exogenous natural products as the most important ‘natural’ drug transporter substrates. doi:10.1101/110437

    DOI: 10.1101/110437

    Major involvement of bacterial components in rheumatoid arthritis and its accompanying oxidative stress, systemic inflammation and hypercoagulability (Journal article)

    Pretorius, E., Akeredolu, O. -O., Soma, P., & Kell, D. B. (2017). Major involvement of bacterial components in rheumatoid arthritis and its accompanying oxidative stress, systemic inflammation and hypercoagulability. EXPERIMENTAL BIOLOGY AND MEDICINE, 242(4), 355-373. doi:10.1177/1535370216681549

    DOI: 10.1177/1535370216681549

    A Bacterial Component to Alzheimer's-Type Dementia Seen via a Systems Biology Approach that Links Iron Dysregulation and Inflammagen Shedding to Disease (Book)

    Pretorius, E., Bester, J., & Kell, D. B. (2017). A Bacterial Component to Alzheimer's-Type Dementia Seen via a Systems Biology Approach that Links Iron Dysregulation and Inflammagen Shedding to Disease (Vol. 5). doi:10.3233/978-1-61499-706-1-313

    DOI: 10.3233/978-1-61499-706-1-313

    Consensus rank orderings of molecular fingerprints illustrate the most genuine similarities between marketed drugs and small endogenous human metabolites, but highlight exogenous natural products as the most important ‘natural’ drug transporter substrates (Journal article)

    O'Hagan, S., & Kell, D. B. (n.d.). Consensus rank orderings of molecular fingerprints illustrate the most genuine similarities between marketed drugs and small endogenous human metabolites, but highlight exogenous natural products as the most important ‘natural’ drug transporter substrates. ADMET and DMPK, 5(2), 85-125. doi:10.5599/admet.5.2.376

    DOI: 10.5599/admet.5.2.376

    Microbes and Alzheimer's Disease (Journal article)

    Itzhaki, R. F., Lathe, R., Balin, B. J., Ball, M. J., Bearer, E. L., Braak, H., . . . Whittum-Hudson, J. A. (2017). Microbes and Alzheimer's Disease. Advances in Alzheimer's Disease, 5, 3-8. doi:10.3233/978-1-61499-706-1-3

    DOI: 10.3233/978-1-61499-706-1-3

    Proteins behaving badly. Substoichiometric molecular control and amplification of the initiation and nature of amyloid fibril formation: lessons from and for blood clotting (Journal article)

    Kell, D. B., & Pretorius, E. (2017). Proteins behaving badly. Substoichiometric molecular control and amplification of the initiation and nature of amyloid fibril formation: lessons from and for blood clotting. PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY, 123, 16-41. doi:10.1016/j.pbiomolbio.2016.08.006

    DOI: 10.1016/j.pbiomolbio.2016.08.006

    SpeedyGenes: Exploiting an Improved Gene Synthesis Method for the Efficient Production of Synthetic Protein Libraries for Directed Evolution. (Chapter)

    Currin, A., Swainston, N., Day, P. J., & Kell, D. B. (2017). SpeedyGenes: Exploiting an Improved Gene Synthesis Method for the Efficient Production of Synthetic Protein Libraries for Directed Evolution.. In Unknown Book (Vol. 1472, pp. 63-78). doi:10.1007/978-1-4939-6343-0_5

    DOI: 10.1007/978-1-4939-6343-0_5

    2016

    SYNBIOCHEM Synthetic Biology Research Centre, Manchester - A UK foundry for fine and speciality chemicals production (Journal article)

    Le Feuvre, R. A., Carbonell, P., Currin, A., Dunstan, M., Fellows, D., Jervis, A. J., . . . Turner, N. J. (2016). SYNBIOCHEM Synthetic Biology Research Centre, Manchester - A UK foundry for fine and speciality chemicals production. SYNTHETIC AND SYSTEMS BIOTECHNOLOGY, 1(4), 271-275. doi:10.1016/j.synbio.2016.07.001

    DOI: 10.1016/j.synbio.2016.07.001

    A Dormant Microbial Component in the Development of Preeclampsia (Journal article)

    Kell, D. B., & Kenny, L. C. (2016). A Dormant Microbial Component in the Development of Preeclampsia. FRONTIERS IN MEDICINE, 3. doi:10.3389/fmed.2016.00060

    DOI: 10.3389/fmed.2016.00060

    The metabolome 18 years on: a concept comes of age (Journal article)

    Kell, D. B., & Oliver, S. G. (2016). The metabolome 18 years on: a concept comes of age. METABOLOMICS, 12(9). doi:10.1007/s11306-016-1108-4

    DOI: 10.1007/s11306-016-1108-4

    Acute induction of anomalous and amyloidogenic blood clotting by molecular amplification of highly substoichiometric levels of bacterial lipopolysaccharide (Journal article)

    Pretorius, E., Mbotwe, S., Bester, J., Robinson, C. J., & Kell, D. B. (2016). Acute induction of anomalous and amyloidogenic blood clotting by molecular amplification of highly substoichiometric levels of bacterial lipopolysaccharide. JOURNAL OF THE ROYAL SOCIETY INTERFACE, 13(122). doi:10.1098/rsif.2016.0539

    DOI: 10.1098/rsif.2016.0539

    MetMaxStruct: A Tversky-Similarity-Based Strategy for Analysing the (Sub)Structural Similarities of Drugs and Endogenous Metabolites (Journal article)

    O'Hagan, S., & Kell, D. B. (2016). MetMaxStruct: A Tversky-Similarity-Based Strategy for Analysing the (Sub)Structural Similarities of Drugs and Endogenous Metabolites. FRONTIERS IN PHARMACOLOGY, 7. doi:10.3389/fphar.2016.00266

    DOI: 10.3389/fphar.2016.00266

    Recon 2.2: from reconstruction to model of human metabolism (Journal article)

    Swainston, N., Smallbone, K., Hefzi, H., Dobson, P. D., Brewer, J., Hanscho, M., . . . Mendes, P. (2016). Recon 2.2: from reconstruction to model of human metabolism. METABOLOMICS, 12(7). doi:10.1007/s11306-016-1051-4

    DOI: 10.1007/s11306-016-1051-4

    A Bacterial Component to Alzheimer's-Type Dementia Seen via a Systems Biology Approach that Links Iron Dysregulation and Inflammagen Shedding to Disease (Journal article)

    Pretorius, E., Bester, J., & Kell, D. B. (2016). A Bacterial Component to Alzheimer's-Type Dementia Seen via a Systems Biology Approach that Links Iron Dysregulation and Inflammagen Shedding to Disease. JOURNAL OF ALZHEIMERS DISEASE, 53(4), 1237-1256. doi:10.3233/JAD-160318

    DOI: 10.3233/JAD-160318

    SYNBIOCHEM - a SynBio foundry for the biosynthesis and sustainable production of fine and speciality chemicals (Journal article)

    Carbonell, P., Currin, A., Dunstan, M., Fellows, D., Jervis, A., Rattray, N. J. W., . . . Turner, N. J. (2016). SYNBIOCHEM - a SynBio foundry for the biosynthesis and sustainable production of fine and speciality chemicals. BIOCHEMICAL SOCIETY TRANSACTIONS, 44, 675-677. doi:10.1042/BST20160009

    DOI: 10.1042/BST20160009

    Microbes and Alzheimer's Disease (Journal article)

    Itzhaki, R. F., Lathe, R., Balin, B. J., Ball, M. J., Bearer, E. L., Braak, H., . . . Whittum-Hudson, J. A. (2016). Microbes and Alzheimer's Disease. JOURNAL OF ALZHEIMERS DISEASE, 51(4), 979-984. doi:10.3233/JAD-160152

    DOI: 10.3233/JAD-160152

    Response to 'The Need for Speed', by Matsson et al. (Journal article)

    Mendes, P., Oliver, S. G., & Kell, D. B. (2016). Response to 'The Need for Speed', by Matsson et al.. TRENDS IN PHARMACOLOGICAL SCIENCES, 37(4), 245-+. doi:10.1016/j.tips.2016.02.004

    DOI: 10.1016/j.tips.2016.02.004

    Implications of endogenous roles of transporters for drug discovery: hitchhiking and metabolite-likeness (Journal article)

    Kell, D. B. (2016). Implications of endogenous roles of transporters for drug discovery: hitchhiking and metabolite-likeness. NATURE REVIEWS DRUG DISCOVERY, 15(2). doi:10.1038/nrd.2015.44

    DOI: 10.1038/nrd.2015.44

    2015

    The transporter-mediated cellular uptake of pharmaceutical drugs is based on their metabolite-likeness and not on their bulk biophysical properties: Towards a systems pharmacology (Journal article)

    Kell, D. B. (2015). The transporter-mediated cellular uptake of pharmaceutical drugs is based on their metabolite-likeness and not on their bulk biophysical properties: Towards a systems pharmacology. Perspectives in Science, 6, 66-83. doi:10.1016/j.pisc.2015.06.004

    DOI: 10.1016/j.pisc.2015.06.004

    The apparent permeabilities of Caco-2 cells to marketed drugs: magnitude, and independence from both biophysical properties and endogenite similarities (Journal article)

    O'Hagan, S., & Kell, D. B. (2015). The apparent permeabilities of Caco-2 cells to marketed drugs: magnitude, and independence from both biophysical properties and endogenite similarities. PEERJ, 3. doi:10.7717/peerj.1405

    DOI: 10.7717/peerj.1405

    Viscoelastic and ultrastructural characteristics of whole blood and plasma in Alzheimer-type dementia, and the possible role of bacterial lipopolysaccharides (LPS) (Journal article)

    Bester, J., Soma, P., Kell, D. B., & Pretorius, E. (2015). Viscoelastic and ultrastructural characteristics of whole blood and plasma in Alzheimer-type dementia, and the possible role of bacterial lipopolysaccharides (LPS). ONCOTARGET, 6(34), 35284-35303. doi:10.18632/oncotarget.6074

    DOI: 10.18632/oncotarget.6074

    On the translocation of bacteria and their lipopolysaccharides between blood and peripheral locations in chronic, inflammatory diseases: the central roles of LPS and LPS-induced cell death (Journal article)

    Kell, D. B., & Pretorius, E. (2015). On the translocation of bacteria and their lipopolysaccharides between blood and peripheral locations in chronic, inflammatory diseases: the central roles of LPS and LPS-induced cell death. INTEGRATIVE BIOLOGY, 7(11), 1339-1377. doi:10.1039/c5ib00158g

    DOI: 10.1039/c5ib00158g

    Fitting Transporter Activities to Cellular Drug Concentrations and Fluxes: Why the Bumblebee Can Fly (Journal article)

    Mendes, P., Oliver, S. G., & Kell, D. B. (2015). Fitting Transporter Activities to Cellular Drug Concentrations and Fluxes: Why the Bumblebee Can Fly. TRENDS IN PHARMACOLOGICAL SCIENCES, 36(11), 710-723. doi:10.1016/j.tips.2015.07.006

    DOI: 10.1016/j.tips.2015.07.006

    Software review: the KNIME workflow environment and its applications in genetic programming and machine learning (Journal article)

    O'Hagan, S., & Kell, D. B. (2015). Software review: the KNIME workflow environment and its applications in genetic programming and machine learning. GENETIC PROGRAMMING AND EVOLVABLE MACHINES, 16(3), 387-391. doi:10.1007/s10710-015-9247-3

    DOI: 10.1007/s10710-015-9247-3

    Individuality, phenotypic differentiation, dormancy and ‘persistence’ in culturable bacterial systems: commonalities shared by environmental, laboratory, and clinical microbiology (Journal article)

    Kell, D., Potgieter, M., & Pretorius, E. (n.d.). Individuality, phenotypic differentiation, dormancy and ‘persistence’ in culturable bacterial systems: commonalities shared by environmental, laboratory, and clinical microbiology. F1000Research, 4, 179. doi:10.12688/f1000research.6709.1

    DOI: 10.12688/f1000research.6709.1

    The dormant blood microbiome in chronic, inflammatory diseases (Journal article)

    Potgieter, M., Bester, J., Kell, D. B., & Pretorius, E. (2015). The dormant blood microbiome in chronic, inflammatory diseases. FEMS MICROBIOLOGY REVIEWS, 39(4), 567-591. doi:10.1093/femsre/fuv013

    DOI: 10.1093/femsre/fuv013

    Understanding the foundations of the structural similarities between marketed drugs and endogenous human metabolites (Journal article)

    O'Hagan, S., & Kell, D. B. (2015). Understanding the foundations of the structural similarities between marketed drugs and endogenous human metabolites. FRONTIERS IN PHARMACOLOGY, 6. doi:10.3389/fphar.2015.00105

    DOI: 10.3389/fphar.2015.00105

    Event-based text mining for biology and functional genomics (Journal article)

    Ananiadou, S., Thompson, P., Nawaz, R., McNaught, J., & Kell, D. B. (2015). Event-based text mining for biology and functional genomics. BRIEFINGS IN FUNCTIONAL GENOMICS, 14(3), 213-230. doi:10.1093/bfgp/elu015

    DOI: 10.1093/bfgp/elu015

    A 'rule of 0.5' for the metabolite-likeness of approved pharmaceutical drugs (Journal article)

    O'Hagan, S., Swainston, N., Handl, J., & Kell, D. B. (2015). A 'rule of 0.5' for the metabolite-likeness of approved pharmaceutical drugs. METABOLOMICS, 11(2), 323-339. doi:10.1007/s11306-014-0733-z

    DOI: 10.1007/s11306-014-0733-z

    A 'rule of 0.5' for the metabolite-likeness of approved pharmaceutical drugs (vol 11, pg 323, 2015) (Journal article)

    O'Hagan, S., Swainston, N., Handl, J., & Kell, D. B. (2015). A 'rule of 0.5' for the metabolite-likeness of approved pharmaceutical drugs (vol 11, pg 323, 2015). METABOLOMICS, 11(2), 340. doi:10.1007/s11306-014-0745-8

    DOI: 10.1007/s11306-014-0745-8

    Membrane transporter engineering in industrial biotechnology and whole cell biocatalysis (Journal article)

    Kell, D. B., Swainston, N., Pir, P., & Oliver, S. G. (2015). Membrane transporter engineering in industrial biotechnology and whole cell biocatalysis. TRENDS IN BIOTECHNOLOGY, 33(4), 237-246. doi:10.1016/j.tibtech.2015.02.001

    DOI: 10.1016/j.tibtech.2015.02.001

    Poorly controlled type 2 diabetes is accompanied by significant morphological and ultrastructural changes in both erythrocytes and in thrombin-generated fibrin: implications for diagnostics (Journal article)

    Pretorius, E., Bester, J., Vermeulen, N., Alummoottil, S., Soma, P., Buys, A. V., & Kell, D. B. (2015). Poorly controlled type 2 diabetes is accompanied by significant morphological and ultrastructural changes in both erythrocytes and in thrombin-generated fibrin: implications for diagnostics. CARDIOVASCULAR DIABETOLOGY, 14. doi:10.1186/s12933-015-0192-5

    DOI: 10.1186/s12933-015-0192-5

    Synthetic biology for the directed evolution of protein biocatalysts: navigating sequence space intelligently (Journal article)

    Currin, A., Swainston, N., Day, P. J., & Kell, D. B. (2015). Synthetic biology for the directed evolution of protein biocatalysts: navigating sequence space intelligently. CHEMICAL SOCIETY REVIEWS, 44(5), 1172-1239. doi:10.1039/c4cs00351a

    DOI: 10.1039/c4cs00351a

    The virtue of innovation: innovation through the lenses of biological evolution (Journal article)

    Kell, D. B., & Lurie-Luke, E. (2015). The virtue of innovation: innovation through the lenses of biological evolution. JOURNAL OF THE ROYAL SOCIETY INTERFACE, 12(103). doi:10.1098/rsif.2014.1183

    DOI: 10.1098/rsif.2014.1183

    Molecular phenotyping of a UK population: defining the human serum metabolome (Journal article)

    Dunn, W. B., Lin, W., Broadhurst, D., Begley, P., Brown, M., Zelena, E., . . . Kell, D. B. (2015). Molecular phenotyping of a UK population: defining the human serum metabolome. METABOLOMICS, 11(1), 9-26. doi:10.1007/s11306-014-0707-1

    DOI: 10.1007/s11306-014-0707-1

    The simultaneous occurrence of both hypercoagulability and hypofibrinolysis in blood and serum during systemic inflammation, and the roles of iron and fibrin(ogen) (Journal article)

    Kell, D. B., & Pretorius, E. (2015). The simultaneous occurrence of both hypercoagulability and hypofibrinolysis in blood and serum during systemic inflammation, and the roles of iron and fibrin(ogen). INTEGRATIVE BIOLOGY, 7(1), 24-52. doi:10.1039/c4ib00173g

    DOI: 10.1039/c4ib00173g

    Individuality, phenotypic differentiation, dormancy and 'persistence' in culturable bacterial systems: commonalities shared by environmental, laboratory, and clinical microbiology. (Journal article)

    Kell, D., Potgieter, M., & Pretorius, E. (2015). Individuality, phenotypic differentiation, dormancy and 'persistence' in culturable bacterial systems: commonalities shared by environmental, laboratory, and clinical microbiology.. F1000Research, 4, 179. doi:10.12688/f1000research.6709.2

    DOI: 10.12688/f1000research.6709.2

    What would be the observable consequences if phospholipid bilayer diffusion of drugs into cells is negligible? (Journal article)

    Kell, D. B. (2015). What would be the observable consequences if phospholipid bilayer diffusion of drugs into cells is negligible?. TRENDS IN PHARMACOLOGICAL SCIENCES, 36(1), 15-21. doi:10.1016/j.tips.2014.10.005

    DOI: 10.1016/j.tips.2014.10.005

    2014

    Alignment by numbers: sequence assembly using compressed numerical representations (Journal article)

    Tapinos, A., Constantinides, B., Kell, D., & Robertson, D. (2014). Alignment by numbers: sequence assembly using compressed numerical representations. doi:10.1101/011940

    DOI: 10.1101/011940

    How drugs get into cells: tested and testable predictions to help discriminate between transporter-mediated uptake and lipoidal bilayer diffusion (Journal article)

    Kell, D. B., & Oliver, S. G. (2014). How drugs get into cells: tested and testable predictions to help discriminate between transporter-mediated uptake and lipoidal bilayer diffusion. FRONTIERS IN PHARMACOLOGY, 5. doi:10.3389/fphar.2014.00231

    DOI: 10.3389/fphar.2014.00231

    Eryptosis as a marker of Parkinson's disease (Journal article)

    Pretorius, E., Swanepoel, A. C., Buys, A. V., Vermeulen, N., Duim, W., & Kell, D. B. (2014). Eryptosis as a marker of Parkinson's disease. AGING-US, 6(10), 788-819. doi:10.18632/aging.100695

    DOI: 10.18632/aging.100695

    Evidence That Multiple Defects in Lipid Regulation Occur before Hyperglycemia during the Prodrome of Type-2 Diabetes (Journal article)

    Anderson, S. G., Dunn, W. B., Banerjee, M., Brown, M., Broadhurst, D. I., Goodacre, R., . . . Cruickshank, J. K. (2014). Evidence That Multiple Defects in Lipid Regulation Occur before Hyperglycemia during the Prodrome of Type-2 Diabetes. PLOS ONE, 9(9). doi:10.1371/journal.pone.0103217

    DOI: 10.1371/journal.pone.0103217

    GeneGenie: optimized oligomer design for directed evolution (Journal article)

    Swainston, N., Currin, A., Day, P. J., & Kell, D. B. (2014). GeneGenie: optimized oligomer design for directed evolution. NUCLEIC ACIDS RESEARCH, 42(W1), W395-W400. doi:10.1093/nar/gku336

    DOI: 10.1093/nar/gku336

    Mental health: drug search on risky path (Journal article)

    Kell, D. (2014). Mental health: drug search on risky path. NATURE, 508(7497), 458. doi:10.1038/508458d

    DOI: 10.1038/508458d

    Profound Morphological Changes in the Erythrocytes and Fibrin Networks of Patients with Hemochromatosis or with Hyperferritinemia, and Their Normalization by Iron Chelators and Other Agents (Journal article)

    Pretorius, E., Bester, J., Vermeulen, N., Lipinski, B., Gericke, G. S., & Kell, D. B. (2014). Profound Morphological Changes in the Erythrocytes and Fibrin Networks of Patients with Hemochromatosis or with Hyperferritinemia, and Their Normalization by Iron Chelators and Other Agents. PLOS ONE, 9(1). doi:10.1371/journal.pone.0085271

    DOI: 10.1371/journal.pone.0085271

    Diagnostic morphology: biophysical indicators for iron-driven inflammatory diseases (Journal article)

    Pretorius, E., & Kell, D. B. (2014). Diagnostic morphology: biophysical indicators for iron-driven inflammatory diseases. INTEGRATIVE BIOLOGY, 6(5), 486-510. doi:10.1039/c4ib00025k

    DOI: 10.1039/c4ib00025k

    Metabolomics and systems pharmacology: why and how to model the human metabolic network for drug discovery (Journal article)

    Kell, D. B., & Goodacre, R. (2014). Metabolomics and systems pharmacology: why and how to model the human metabolic network for drug discovery. DRUG DISCOVERY TODAY, 19(2), 171-182. doi:10.1016/j.drudis.2013.07.014

    DOI: 10.1016/j.drudis.2013.07.014

    Metabolomics and systems pharmacology: why and how to model the human metabolic network for drug discovery (vol 19, pg 171, 2014) (Journal article)

    Kell, D. B., & Goodacre, R. (2014). Metabolomics and systems pharmacology: why and how to model the human metabolic network for drug discovery (vol 19, pg 171, 2014). DRUG DISCOVERY TODAY, 19(11), 1828. doi:10.1016/j.drudis.2014.03.019

    DOI: 10.1016/j.drudis.2014.03.019

    Serum ferritin is an important inflammatory disease marker, as it is mainly a leakage product from damaged cells (Journal article)

    Kell, D. B., & Pretorius, E. (2014). Serum ferritin is an important inflammatory disease marker, as it is mainly a leakage product from damaged cells. METALLOMICS, 6(4), 748-773. doi:10.1039/c3mt00347g

    DOI: 10.1039/c3mt00347g

    SpeedyGenes: an improved gene synthesis method for the efficient production of error-corrected, synthetic protein libraries for directed evolution (Journal article)

    Currin, A., Swainston, N., Day, P. J., & Kell, D. B. (2014). SpeedyGenes: an improved gene synthesis method for the efficient production of error-corrected, synthetic protein libraries for directed evolution. PROTEIN ENGINEERING DESIGN & SELECTION, 27(9), 273-280. doi:10.1093/protein/gzu029

    DOI: 10.1093/protein/gzu029

    Yeast cells with impaired drug resistance accumulate glycerol and glucose (Journal article)

    Dikicioglu, D., Oc, S., Rash, B. M., Dunn, W. B., Pir, P., Kell, D. B., . . . Oliver, S. G. (2014). Yeast cells with impaired drug resistance accumulate glycerol and glucose. MOLECULAR BIOSYSTEMS, 10(1), 93-102. doi:10.1039/c2mb25512j

    DOI: 10.1039/c2mb25512j

    2013

    High ferritin levels have major effects on the morphology of erythrocytes in Alzheimer's disease (Journal article)

    Bester, J., Buys, A. V., Lipinski, B., Kell, D. B., & Pretorius, E. (2013). High ferritin levels have major effects on the morphology of erythrocytes in Alzheimer's disease. FRONTIERS IN AGING NEUROSCIENCE, 5. doi:10.3389/fnagi.2013.00088

    DOI: 10.3389/fnagi.2013.00088

    Finding novel pharmaceuticals in the systems biology era using multiple effective drug targets, phenotypic screening and knowledge of transporters: where drug discovery went wrong and how to fix it (Journal article)

    Kell, D. B. (2013). Finding novel pharmaceuticals in the systems biology era using multiple effective drug targets, phenotypic screening and knowledge of transporters: where drug discovery went wrong and how to fix it. FEBS JOURNAL, 280(23), 5957-5980. doi:10.1111/febs.12268

    DOI: 10.1111/febs.12268

    Classroom orchestration: Synthesis (Journal article)

    Roschelle, J., Dimitriadis, Y., & Hoppe, U. (2013). Classroom orchestration: Synthesis. COMPUTERS & EDUCATION, 69, 523-526. doi:10.1016/j.compedu.2013.04.010

    DOI: 10.1016/j.compedu.2013.04.010

    Path2Models: large-scale generation of computational models from biochemical pathway maps (Journal article)

    Buechel, F., Rodriguez, N., Swainston, N., Wrzodek, C., Czauderna, T., Keller, R., . . . Le Novere, N. (2013). Path2Models: large-scale generation of computational models from biochemical pathway maps. BMC SYSTEMS BIOLOGY, 7. doi:10.1186/1752-0509-7-116

    DOI: 10.1186/1752-0509-7-116

    A model of yeast glycolysis based on a consistent kinetic characterisation of all its enzymes (Journal article)

    Smallbone, K., Messiha, H. L., Carroll, K. M., Winder, C. L., Malys, N., Dunn, W. B., . . . Mendes, P. (2013). A model of yeast glycolysis based on a consistent kinetic characterisation of all its enzymes. FEBS LETTERS, 587(17), 2832-2841. doi:10.1016/j.febslet.2013.06.043

    DOI: 10.1016/j.febslet.2013.06.043

    An analysis of a 'community-driven' reconstruction of the human metabolic network (Journal article)

    Swainston, N., Mendes, P., & Kell, D. B. (2013). An analysis of a 'community-driven' reconstruction of the human metabolic network. METABOLOMICS, 9(4), 757-764. doi:10.1007/s11306-013-0564-3

    DOI: 10.1007/s11306-013-0564-3

    A method for integrating and ranking the evidence for biochemical pathways by mining reactions from text (Conference Paper)

    Miwa, M., Ohta, T., Rak, R., Rowley, A., Kell, D. B., Pyysalo, S., & Ananiadou, S. (2013). A method for integrating and ranking the evidence for biochemical pathways by mining reactions from text. In BIOINFORMATICS Vol. 29 (pp. 44-52). doi:10.1093/bioinformatics/btt227

    DOI: 10.1093/bioinformatics/btt227

    A novel method for assessing the role of iron and its functional chelation in fibrin fibril formation: the use of scanning electron microscopy (Journal article)

    Pretorius, E., Vermeulen, N., Bester, J., Lipinski, B., & Kell, D. B. (2013). A novel method for assessing the role of iron and its functional chelation in fibrin fibril formation: the use of scanning electron microscopy. TOXICOLOGY MECHANISMS AND METHODS, 23(5), 352-359. doi:10.3109/15376516.2012.762082

    DOI: 10.3109/15376516.2012.762082

    A community-driven global reconstruction of human metabolism (Journal article)

    Thiele, I., Swainston, N., Fleming, R. M. T., Hoppe, A., Sahoo, S., Aurich, M. K., . . . Palsson, B. O. (2013). A community-driven global reconstruction of human metabolism. NATURE BIOTECHNOLOGY, 31(5), 419-+. doi:10.1038/nbt.2488

    DOI: 10.1038/nbt.2488

    Genetics and iron in the systems biology of Parkinson's disease and some related disorders (Journal article)

    Funke, C., Schneider, S. A., Berg, D., & Kell, D. B. (2013). Genetics and iron in the systems biology of Parkinson's disease and some related disorders. NEUROCHEMISTRY INTERNATIONAL, 62(5), 637-652. doi:10.1016/j.neuint.2012.11.015

    DOI: 10.1016/j.neuint.2012.11.015

    The promiscuous binding of pharmaceutical drugs and their transporter-mediated uptake into cells: what we (need to) know and how we can do so (Journal article)

    Kell, D. B., Dobson, P. D., Bilsland, E., & Oliver, S. G. (2013). The promiscuous binding of pharmaceutical drugs and their transporter-mediated uptake into cells: what we (need to) know and how we can do so. DRUG DISCOVERY TODAY, 18(5-6), 218-239. doi:10.1016/j.drudis.2012.11.008

    DOI: 10.1016/j.drudis.2012.11.008

    2012

    Exploiting Genomic Knowledge in Optimising Molecular Breeding Programmes: Algorithms from Evolutionary Computing (Journal article)

    O'Hagan, S., Knowles, J., & Kell, D. B. (2012). Exploiting Genomic Knowledge in Optimising Molecular Breeding Programmes: Algorithms from Evolutionary Computing. PLOS ONE, 7(11). doi:10.1371/journal.pone.0048862

    DOI: 10.1371/journal.pone.0048862

    Reviews turn facts into understanding (Journal article)

    Kell, D. B. (2012). Reviews turn facts into understanding. NATURE, 490(7418), 37. doi:10.1038/490037e

    DOI: 10.1038/490037e

    The metabolome of human placental tissue: investigation of first trimester tissue and changes related to preeclampsia in late pregnancy (Journal article)

    Dunn, W. B., Brown, M., Worton, S. A., Davies, K., Jones, R. L., Kell, D. B., & Heazell, A. E. P. (2012). The metabolome of human placental tissue: investigation of first trimester tissue and changes related to preeclampsia in late pregnancy. METABOLOMICS, 8(4), 579-597. doi:10.1007/s11306-011-0348-6

    DOI: 10.1007/s11306-011-0348-6

    Improving metabolic flux predictions using absolute gene expression data (Journal article)

    Lee, D., Smallbone, K., Dunn, W. B., Murabito, E., Winder, C. L., Kell, D. B., . . . Swainston, N. (2012). Improving metabolic flux predictions using absolute gene expression data. BMC SYSTEMS BIOLOGY, 6. doi:10.1186/1752-0509-6-73

    DOI: 10.1186/1752-0509-6-73

    Large-scale sequestration of atmospheric carbon via plant roots in natural and agricultural ecosystems: why and how (Journal article)

    Kell, D. B. (2012). Large-scale sequestration of atmospheric carbon via plant roots in natural and agricultural ecosystems: why and how. PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES, 367(1595), 1589-1597. doi:10.1098/rstb.2011.0244

    DOI: 10.1098/rstb.2011.0244

    Short- and long-term dynamic responses of the metabolic network and gene expression in yeast to a transient change in the nutrient environment (Journal article)

    Dikicioglu, D., Dunn, W. B., Kell, D. B., Kirdar, B., & Oliver, S. G. (2012). Short- and long-term dynamic responses of the metabolic network and gene expression in yeast to a transient change in the nutrient environment. MOLECULAR BIOSYSTEMS, 8(6), 1760-1774. doi:10.1039/c2mb05443d

    DOI: 10.1039/c2mb05443d

    Extracting semantically enriched events from biomedical literature (Journal article)

    Miwa, M., Thompson, P., McNaught, J., Kell, D. B., & Ananiadou, S. (2012). Extracting semantically enriched events from biomedical literature. BMC BIOINFORMATICS, 13. doi:10.1186/1471-2105-13-108

    DOI: 10.1186/1471-2105-13-108

    Genome-wide analysis of longevity in nutrient-deprived Saccharomyces cerevisiae reveals importance of recycling in maintaining cell viability (Journal article)

    Davey, H. M., Cross, E. J. M., Davey, C. L., Gkargkas, K., Delneri, D., Hoyle, D. C., . . . Griffith, G. W. (2012). Genome-wide analysis of longevity in nutrient-deprived Saccharomyces cerevisiae reveals importance of recycling in maintaining cell viability. ENVIRONMENTAL MICROBIOLOGY, 14(5), 1249-1260. doi:10.1111/j.1462-2920.2012.02705.x

    DOI: 10.1111/j.1462-2920.2012.02705.x

    A systematic survey of the response of a model NF-kappa B signalling pathway to TNF alpha stimulation (Journal article)

    Wang, Y., Paszek, P., Horton, C. A., Yue, H., White, M. R. H., Kell, D. B., . . . Broomhead, D. S. (2012). A systematic survey of the response of a model NF-kappa B signalling pathway to TNF alpha stimulation. JOURNAL OF THEORETICAL BIOLOGY, 297, 137-147. doi:10.1016/j.jtbi.2011.12.014

    DOI: 10.1016/j.jtbi.2011.12.014

    Scientific discovery as a combinatorial optimisation problem: How best to navigate the landscape of possible experiments? (Journal article)

    Kell, D. B. (2012). Scientific discovery as a combinatorial optimisation problem: How best to navigate the landscape of possible experiments?. BIOESSAYS, 34(3), 236-244. doi:10.1002/bies.201100144

    DOI: 10.1002/bies.201100144

    The genetic control of growth rate: a systems biology study in yeast (Journal article)

    Pir, P., Gutteridge, A., Wu, J., Rash, B., Kell, D. B., Zhang, N., & Oliver, S. G. (2012). The genetic control of growth rate: a systems biology study in yeast. BMC SYSTEMS BIOLOGY, 6. doi:10.1186/1752-0509-6-4

    DOI: 10.1186/1752-0509-6-4

    Automated workflows for accurate mass-based putative metabolite identification in LC/MS-derived metabolomic datasets (vol 27, pg 1108, 2011) (Journal article)

    Brown, M., Wedge, D. C., Goodacre, R., Kell, D. B., Baker, P. N., Kenny, L. C., . . . Dunn, W. B. (2012). Automated workflows for accurate mass-based putative metabolite identification in LC/MS-derived metabolomic datasets (vol 27, pg 1108, 2011). BIOINFORMATICS, 28(1), 149. doi:10.1093/bioinformatics/btr601

    DOI: 10.1093/bioinformatics/btr601

    2011

    Absolute Quantification of the Glycolytic Pathway in Yeast: DEPLOYMENT OF A COMPLETE QconCAT APPROACH (Journal article)

    Carroll, K. M., Simpson, D. M., Eyers, C. E., Knight, C. G., Brownridge, P., Dunn, W. B., . . . Beynon, R. J. (2011). Absolute Quantification of the Glycolytic Pathway in Yeast: DEPLOYMENT OF A COMPLETE QconCAT APPROACH. MOLECULAR & CELLULAR PROTEOMICS, 10(12). doi:10.1074/mcp.M111.007633

    DOI: 10.1074/mcp.M111.007633

    The SuBliMinaL Toolbox: automating steps in the reconstruction of metabolic networks. (Journal article)

    Swainston, N., Smallbone, K., Mendes, P., Kell, D., & Paton, N. (2011). The SuBliMinaL Toolbox: automating steps in the reconstruction of metabolic networks.. Journal of integrative bioinformatics, 8(2), 186. doi:10.2390/biecoll-jib-2011-186

    DOI: 10.2390/biecoll-jib-2011-186

    Controlled vocabularies and semantics in systems biology (Journal article)

    Courtot, M., Juty, N., Knuepfer, C., Waltemath, D., Zhukova, A., Draeger, A., . . . Le Novere, N. (2011). Controlled vocabularies and semantics in systems biology. MOLECULAR SYSTEMS BIOLOGY, 7. doi:10.1038/msb.2011.77

    DOI: 10.1038/msb.2011.77

    Genome-wide assessment of the carriers involved in the cellular uptake of drugs: a model system in yeast (Journal article)

    Lanthaler, K., Bilsland, E., Dobson, P. D., Moss, H. J., Pir, P., Kell, D. B., & Oliver, S. G. (2011). Genome-wide assessment of the carriers involved in the cellular uptake of drugs: a model system in yeast. BMC BIOLOGY, 9. doi:10.1186/1741-7007-9-70

    DOI: 10.1186/1741-7007-9-70

    Efficient discovery of anti-inflammatory small-molecule combinations using evolutionary computing (Journal article)

    Small, B. G., McColl, B. W., Allmendinger, R., Pahle, J., Lopez-Castejon, G., Rothwell, N. J., . . . Kell, D. B. (2011). Efficient discovery of anti-inflammatory small-molecule combinations using evolutionary computing. NATURE CHEMICAL BIOLOGY, 7(12), 902-908. doi:10.1038/NCHEMBIO.689

    DOI: 10.1038/NCHEMBIO.689

    Concussion's impact (Journal article)

    Kell, D. (2011). Concussion's impact. NEW SCIENTIST, 211(2831), 38. doi:10.1016/S0262-4079(11)62341-5

    DOI: 10.1016/S0262-4079(11)62341-5

    Breeding crop plants with deep roots: their role in sustainable carbon, nutrient and water sequestration (Journal article)

    Kell, D. B. (2011). Breeding crop plants with deep roots: their role in sustainable carbon, nutrient and water sequestration. ANNALS OF BOTANY, 108(3), 407-418. doi:10.1093/aob/mcr175

    DOI: 10.1093/aob/mcr175

    Metabolic Profiling Uncovers a Phenotypic Signature of Small for Gestational Age in Early Pregnancy (Journal article)

    Horgan, R. P., Broadhurst, D. I., Walsh, S. K., Dunn, W. B., Brown, M., Roberts, C. T., . . . Kenny, L. C. (2011). Metabolic Profiling Uncovers a Phenotypic Signature of Small for Gestational Age in Early Pregnancy. JOURNAL OF PROTEOME RESEARCH, 10(8), 3660-3673. doi:10.1021/pr2002897

    DOI: 10.1021/pr2002897

    Pharmaceutical drug transport: the issues and the implications that it is essentially carrier-mediated only (Journal article)

    Kell, D. B., Dobson, P. D., & Oliver, S. G. (2011). Pharmaceutical drug transport: the issues and the implications that it is essentially carrier-mediated only. DRUG DISCOVERY TODAY, 16(15-16), 704-714. doi:10.1016/j.drudis.2011.05.010

    DOI: 10.1016/j.drudis.2011.05.010

    Procedures for large-scale metabolic profiling of serum and plasma using gas chromatography and liquid chromatography coupled to mass spectrometry (Journal article)

    Dunn, W. B., Broadhurst, D., Begley, P., Zelena, E., Francis-McIntyre, S., Anderson, N., . . . Human, S. M. H. U. S. E. R. M. E. T. C. (2011). Procedures for large-scale metabolic profiling of serum and plasma using gas chromatography and liquid chromatography coupled to mass spectrometry. NATURE PROTOCOLS, 6(7), 1060-1083. doi:10.1038/nprot.2011.335

    DOI: 10.1038/nprot.2011.335

    Automated workflows for accurate mass-based putative metabolite identification in LC/MS-derived metabolomic datasets (Journal article)

    Brown, M., Wedge, D. C., Goodacre, R., Kell, D. B., Baker, P. N., Kenny, L. C., . . . Dunn, W. B. (2011). Automated workflows for accurate mass-based putative metabolite identification in LC/MS-derived metabolomic datasets. BIOINFORMATICS, 27(8), 1108-1112. doi:10.1093/bioinformatics/btr079

    DOI: 10.1093/bioinformatics/btr079

    Mining metabolites: extracting the yeast metabolome from the literature (Journal article)

    Nobata, C., Dobson, P. D., Iqbal, S. A., Mendes, P., Tsujii, J., Kell, D. B., & Ananiadou, S. (2011). Mining metabolites: extracting the yeast metabolome from the literature. METABOLOMICS, 7(1), 94-101. doi:10.1007/s11306-010-0251-6

    DOI: 10.1007/s11306-010-0251-6

    Predicting the points of interaction of small molecules in the NF-kappa B pathway (Journal article)

    Patel, Y., Heyward, C. A., White, M. R. H., & Kell, D. B. (2011). Predicting the points of interaction of small molecules in the NF-kappa B pathway. BMC SYSTEMS BIOLOGY, 5. doi:10.1186/1752-0509-5-32

    DOI: 10.1186/1752-0509-5-32

    Interactions among oscillatory pathways in NF-kappa B signaling (Journal article)

    Wang, Y., Paszek, P., Horton, C. A., Kell, D. B., White, M. R. H., Broomhead, D. S., & Muldoon, M. R. (2011). Interactions among oscillatory pathways in NF-kappa B signaling. BMC SYSTEMS BIOLOGY, 5. doi:10.1186/1752-0509-5-23

    DOI: 10.1186/1752-0509-5-23

    Understanding the languages of cells: Network modelling in metabolic systems biology and biotechnology: why, how and whither (Journal article)

    Kell, D. B. (2011). Understanding the languages of cells: Network modelling in metabolic systems biology and biotechnology: why, how and whither. The Biochemist, 33(1), 4-7. doi:10.1042/bio03301004

    DOI: 10.1042/bio03301004

    SYSTEMS BIOLOGY Metabolites do social networking (Journal article)

    Kell, D. B. (2011). SYSTEMS BIOLOGY Metabolites do social networking. NATURE CHEMICAL BIOLOGY, 7(1), 7-8. doi:10.1038/nchembio.505

    DOI: 10.1038/nchembio.505

    2010

    Systematic integration of experimental data and models in systems biology (Journal article)

    Li, P., Dada, J. O., Jameson, D., Spasic, I., Swainston, N., Carroll, K., . . . Paton, N. W. (2010). Systematic integration of experimental data and models in systems biology. BMC BIOINFORMATICS, 11. doi:10.1186/1471-2105-11-582

    DOI: 10.1186/1471-2105-11-582

    Towards a unifying, systems biology understanding of large-scale cellular death and destruction caused by poorly liganded iron: Parkinson's, Huntington's, Alzheimer's, prions, bactericides, chemical toxicology and others as examples (Journal article)

    Kell, D. B. (2010). Towards a unifying, systems biology understanding of large-scale cellular death and destruction caused by poorly liganded iron: Parkinson's, Huntington's, Alzheimer's, prions, bactericides, chemical toxicology and others as examples. ARCHIVES OF TOXICOLOGY, 84(11), 825-889. doi:10.1007/s00204-010-0577-x

    DOI: 10.1007/s00204-010-0577-x

    Further developments towards a genome-scale metabolic model of yeast (Journal article)

    Dobson, P. D., Smallbone, K., Jameson, D., Simeonidis, E., Lanthaler, K., Pir, P., . . . Mendes, P. (2010). Further developments towards a genome-scale metabolic model of yeast. BMC SYSTEMS BIOLOGY, 4. doi:10.1186/1752-0509-4-145

    DOI: 10.1186/1752-0509-4-145

    Changes in the Metabolic Footprint of Placental Explant-Conditioned Medium Cultured in Different Oxygen Tensions from Placentas of Small for Gestational Age and Normal Pregnancies (Journal article)

    Horgan, R. P., Broadhurst, D. I., Dunn, W. B., Brown, M., Heazell, A. E. P., Kell, D. B., . . . Kenny, L. C. (2010). Changes in the Metabolic Footprint of Placental Explant-Conditioned Medium Cultured in Different Oxygen Tensions from Placentas of Small for Gestational Age and Normal Pregnancies. PLACENTA, 31(10), 893-901. doi:10.1016/j.placenta.2010.07.002

    DOI: 10.1016/j.placenta.2010.07.002

    Robust Early Pregnancy Prediction of Later Preeclampsia Using Metabolomic Biomarkers (Journal article)

    Kenny, L. C., Broadhurst, D. I., Dunn, W., Brown, M., North, R. A., McCowan, L., . . . Endpoints, S. P. (2010). Robust Early Pregnancy Prediction of Later Preeclampsia Using Metabolomic Biomarkers. HYPERTENSION, 56(4), 741-749. doi:10.1161/HYPERTENSIONAHA.110.157297

    DOI: 10.1161/HYPERTENSIONAHA.110.157297

    Utopia documents: linking scholarly literature with research data (Journal article)

    Attwood, T. K., Kell, D. B., McDermott, P., Marsh, J., Pettifer, S. R., & Thorne, D. (2010). Utopia documents: linking scholarly literature with research data. BIOINFORMATICS, 26(18), i568-i574. doi:10.1093/bioinformatics/btq383

    DOI: 10.1093/bioinformatics/btq383

    Convergent evolution to an aptamer observed in small populations on DNA microarrays (Journal article)

    Rowe, W., Platt, M., Wedge, D. C., Day, P. J. R., Kell, D. B., & Knowles, J. D. (2010). Convergent evolution to an aptamer observed in small populations on DNA microarrays. PHYSICAL BIOLOGY, 7(3). doi:10.1088/1478-3975/7/3/036007

    DOI: 10.1088/1478-3975/7/3/036007

    Enzyme kinetics informatics: from instrument to browser (Journal article)

    Swainston, N., Golebiewski, M., Messiha, H. L., Malys, N., Kania, R., Kengne, S., . . . Rojas, I. (2010). Enzyme kinetics informatics: from instrument to browser. FEBS JOURNAL, 277(18), 3769-3779. doi:10.1111/j.1742-4658.2010.07778.x

    DOI: 10.1111/j.1742-4658.2010.07778.x

    Predictive models for population performance on real biological fitness landscapes (Journal article)

    Rowe, W., Wedge, D. C., Platt, M., Kell, D. B., & Knowles, J. (2010). Predictive models for population performance on real biological fitness landscapes. BIOINFORMATICS, 26(17), 2145-2152. doi:10.1093/bioinformatics/btq353

    DOI: 10.1093/bioinformatics/btq353

    Event extraction for systems biology by text mining the literature (Journal article)

    Ananiadou, S., Pyysalo, S., Tsujii, J., & Kell, D. B. (2010). Event extraction for systems biology by text mining the literature. TRENDS IN BIOTECHNOLOGY, 28(7), 381-390. doi:10.1016/j.tibtech.2010.04.005

    DOI: 10.1016/j.tibtech.2010.04.005

    Arcadia: a visualization tool for metabolic pathways (Journal article)

    Villeger, A. C., Pettifer, S. R., & Kell, D. B. (2010). Arcadia: a visualization tool for metabolic pathways. BIOINFORMATICS, 26(11), 1470-1471. doi:10.1093/bioinformatics/btq154

    DOI: 10.1093/bioinformatics/btq154

    Analysis of a complete DNA-protein affinity landscape (Journal article)

    Rowe, W., Platt, M., Wedge, D. C., Day, P. J., Kell, D. B., & Knowles, J. (2010). Analysis of a complete DNA-protein affinity landscape. JOURNAL OF THE ROYAL SOCIETY INTERFACE, 7(44), 397-408. doi:10.1098/rsif.2009.0193

    DOI: 10.1098/rsif.2009.0193

    Systems microbiology (Journal article)

    Kell, D. B. (2010). Systems microbiology. Microbiology Today, 37(1), 14-15.

    2009

    Calling International Rescue: knowledge lost in literature and data landslide! (Journal article)

    Attwood, T. K., Kell, D. B., McDermott, P., Marsh, J., Pettifer, S. R., & Thorne, D. (2009). Calling International Rescue: knowledge lost in literature and data landslide!. BIOCHEMICAL JOURNAL, 424, 317-333. doi:10.1042/BJ20091474

    DOI: 10.1042/BJ20091474

    Real-time vapour sensing using an OFET-based electronic nose and genetic programming (Journal article)

    Wedge, D. C., Das, A., Dost, R., Kettle, J., Madec, M. -B., Morrison, J. J., . . . Turner, M. L. (2009). Real-time vapour sensing using an OFET-based electronic nose and genetic programming. SENSORS AND ACTUATORS B-CHEMICAL, 143(1), 365-372. doi:10.1016/j.snb.2009.09.030

    DOI: 10.1016/j.snb.2009.09.030

    Analysis of aptamer sequence activity relationships (Journal article)

    Platt, M., Rowe, W., Knowles, J., Day, P. J., & Kell, D. B. (2009). Analysis of aptamer sequence activity relationships. INTEGRATIVE BIOLOGY, 1(1), 116-122. doi:10.1039/b814892a

    DOI: 10.1039/b814892a

    Calling International Rescue: Knowledge lost in literature and data landslide! (Journal article)

    Attwood, T. K., Kell, D. B., McDermott, P., Marsh, J., Pettifer, S. R., & Thorne, D. (2009). Calling International Rescue: Knowledge lost in literature and data landslide!. The Biochemist, 31(6), 23-38. doi:10.1042/bio03106023

    DOI: 10.1042/bio03106023

    Changes in the Metabolic Footprint of Placental Explant-Conditioned Culture Medium Identifies Metabolic Disturbances Related to Hypoxia and Pre-Eclampsia (Journal article)

    Dunn, W. B., Brown, M., Worton, S. A., Crocker, I. P., Broadhurst, D., Horgan, R., . . . Heazell, A. E. P. (2009). Changes in the Metabolic Footprint of Placental Explant-Conditioned Culture Medium Identifies Metabolic Disturbances Related to Hypoxia and Pre-Eclampsia. PLACENTA, 30(11), 974-980. doi:10.1016/j.placenta.2009.08.008

    DOI: 10.1016/j.placenta.2009.08.008

    Altered plasma metabolome in early pregnancy in women who develop a small for gestational age baby (Conference Paper)

    Horgan, R., Broadhurst, D., Brown, M., Dunn, W., Kell, D., Baker, P., & Kenny, L. (2009). Altered plasma metabolome in early pregnancy in women who develop a small for gestational age baby. In BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY Vol. 116 (pp. 1409). Retrieved from http://gateway.webofknowledge.com/

    Matrix Method for Determining Steps Most Rate-Limiting to Metabolic Fluxes in Biotechnological Processes (Journal article)

    Westerhoff, H. V., & Kell, D. B. (2009). Matrix Method for Determining Steps Most Rate-Limiting to Metabolic Fluxes in Biotechnological Processes. BIOTECHNOLOGY AND BIOENGINEERING, 104(1), 3-9. Retrieved from http://gateway.webofknowledge.com/

    The Systems Biology Graphical Notation (vol 27, pg 735, 2009) (Journal article)

    Le Novere, N., Hucka, M., Mi, H., Moodie, S., Schreiber, F., Sorokin, A., . . . Kitano, H. (2009). The Systems Biology Graphical Notation (vol 27, pg 735, 2009). NATURE BIOTECHNOLOGY, 27(9), 864. doi:10.1038/nbt0909-864d

    DOI: 10.1038/nbt0909-864d

    Development and Performance of a Gas Chromatography-Time-of-Flight Mass Spectrometry Analysis for Large-Scale Nontargeted Metabolomic Studies of Human Serum (Journal article)

    Begley, P., Francis-McIntyre, S., Dunn, W. B., Broadhurst, D. I., Halsall, A., Tseng, A., . . . Consortium, H. U. S. E. R. M. E. T. (2009). Development and Performance of a Gas Chromatography-Time-of-Flight Mass Spectrometry Analysis for Large-Scale Nontargeted Metabolomic Studies of Human Serum. ANALYTICAL CHEMISTRY, 81(16), 7038-7046. doi:10.1021/ac9011599

    DOI: 10.1021/ac9011599

    Optimal construction of a fast and accurate polarisable water potential based on multipole moments trained by machine learning (Journal article)

    Handley, C. M., Hawe, G. I., Kell, D. B., & Popelier, P. L. A. (2009). Optimal construction of a fast and accurate polarisable water potential based on multipole moments trained by machine learning. PHYSICAL CHEMISTRY CHEMICAL PHYSICS, 11(30), 6365-6376. doi:10.1039/b905748j

    DOI: 10.1039/b905748j

    The Systems Biology Graphical Notation (Journal article)

    Le Novere, N., Hucka, M., Mi, H., Moodie, S., Schreiber, F., Sorokin, A., . . . Kitano, H. (2009). The Systems Biology Graphical Notation. NATURE BIOTECHNOLOGY, 27(8), 735-741. doi:10.1038/nbt.1558

    DOI: 10.1038/nbt.1558

    Journal club. A systems biologist ponders how disparate ideas can sometimes come together beautifully. (Journal article)

    Kell, D. (2009). Journal club. A systems biologist ponders how disparate ideas can sometimes come together beautifully.. Nature, 460(7256), 669. doi:10.1038/460669e

    DOI: 10.1038/460669e

    BACTERIAL PHEROMONE AND USE THEREOF (Journal article)

    MUKAMOLOVA GALINA V., KAPRELYANTS ARSENY S., YOUNG DANIELLE I., KELL DOUGLAS B., & YOUNG MICHAEL. (2009). BACTERIAL PHEROMONE AND USE THEREOF.

    Information management for high content live cell imaging (Journal article)

    Jameson, D., Turner, D. A., Ankers, J., Kennedy, S., Ryan, S., Swainston, N., . . . Paton, N. W. (2009). Information management for high content live cell imaging. BMC BIOINFORMATICS, 10. doi:10.1186/1471-2105-10-226

    DOI: 10.1186/1471-2105-10-226

    Deterministic mathematical models of the cAMP pathway in Saccharomyces cerevisiae (Journal article)

    Williamson, T., Schwartz, J. -M., Kell, D. B., & Stateva, L. (2009). Deterministic mathematical models of the cAMP pathway in Saccharomyces cerevisiae. BMC SYSTEMS BIOLOGY, 3. doi:10.1186/1752-0509-3-70

    DOI: 10.1186/1752-0509-3-70

    Aptamer evolution for array-based diagnostics (Journal article)

    Platt, M., Rowe, W., Wedge, D. C., Kell, D. B., Knowles, J., & Day, P. J. R. (2009). Aptamer evolution for array-based diagnostics. ANALYTICAL BIOCHEMISTRY, 390(2), 203-205. doi:10.1016/j.ab.2009.04.013

    DOI: 10.1016/j.ab.2009.04.013

    Visualising biological data: a semantic approach to tool and database integration (Conference Paper)

    Pettifer, S., Thorne, D., McDermott, P., Marsh, J., Villeger, A., Kell, D. B., & Attwood, T. K. (2009). Visualising biological data: a semantic approach to tool and database integration. In BMC BIOINFORMATICS Vol. 10. doi:10.1186/1471-2105-10-S6-S19

    DOI: 10.1186/1471-2105-10-S6-S19

    KiPar, a tool for systematic information retrieval regarding parameters for kinetic modelling of yeast metabolic pathways (Journal article)

    Spasic, I., Simeonidis, E., Messiha, H. L., Paton, N. W., & Kell, D. B. (2009). KiPar, a tool for systematic information retrieval regarding parameters for kinetic modelling of yeast metabolic pathways. BIOINFORMATICS, 25(11), 1404-1411. doi:10.1093/bioinformatics/btp175

    DOI: 10.1093/bioinformatics/btp175

    Dormant microbes: time to revive some old ideas (Journal article)

    Kell, D. (2009). Dormant microbes: time to revive some old ideas. NATURE, 458(7240), 831. doi:10.1038/458831b

    DOI: 10.1038/458831b

    Pulsatile Stimulation Determines Timing and Specificity of NF-kappa B-Dependent Transcription (Journal article)

    Ashall, L., Horton, C. A., Nelson, D. E., Paszek, P., Harper, C. V., Sillitoe, K., . . . White, M. R. H. (2009). Pulsatile Stimulation Determines Timing and Specificity of NF-kappa B-Dependent Transcription. SCIENCE, 324(5924), 242-246. doi:10.1126/science.1164860

    DOI: 10.1126/science.1164860

    Low cost, portable, fast multiparameter data acquisition system for organic transistor odour sensors (Journal article)

    Das, A., Dost, R., Richardson, T. H., Grell, M., Wedge, D. C., Kell, D. B., . . . Turner, M. L. (2009). Low cost, portable, fast multiparameter data acquisition system for organic transistor odour sensors. SENSORS AND ACTUATORS B-CHEMICAL, 137(2), 586-591. doi:10.1016/j.snb.2009.01.006

    DOI: 10.1016/j.snb.2009.01.006

    Clustering of NF-kappa B inhibitors by their interaction in the signaling pathway (Conference Paper)

    Patel, Y., Heyward, C., & Kell, D. B. (2009). Clustering of NF-kappa B inhibitors by their interaction in the signaling pathway. In ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY Vol. 237. Retrieved from http://gateway.webofknowledge.com/

    In silico modelling of directed evolution: Implications for experimental design and stepwise evolution (Journal article)

    Wedge, D. C., Rowe, W., Kell, D. B., & Knowles, J. (2009). In silico modelling of directed evolution: Implications for experimental design and stepwise evolution. JOURNAL OF THEORETICAL BIOLOGY, 257(1), 131-141. doi:10.1016/j.jtbi.2008.11.005

    DOI: 10.1016/j.jtbi.2008.11.005

    Altered Plasma Metabolome in Early Pregnancy in Women Who Develop a Small for Gestational Age Baby (Conference Paper)

    Horgan, R. P., Broadhurst, D. I., Brown, M. C., Warwick, B. D., Kell, D. B., Baker, P. N., & Kenny, L. C. (2009). Altered Plasma Metabolome in Early Pregnancy in Women Who Develop a Small for Gestational Age Baby. In REPRODUCTIVE SCIENCES Vol. 16 (pp. 137A-138A). Retrieved from http://gateway.webofknowledge.com/

    Changes in the Metabolic Profile of Placental Villous Explants Cultured in Different Oxygen Tensions from Placentas of Small for Gestational Age and Normal Pregnancies (Conference Paper)

    Horgan, R. P., Brown, M. C., Dunn, W. B., Heazell, A. E., Kell, D. B., Baker, P. N., . . . Broadhurst, D. I. (2009). Changes in the Metabolic Profile of Placental Villous Explants Cultured in Different Oxygen Tensions from Placentas of Small for Gestational Age and Normal Pregnancies. In REPRODUCTIVE SCIENCES Vol. 16 (pp. 345A). Retrieved from http://gateway.webofknowledge.com/

    Early Pregnancy Prediction of Preeclampsia Using Metabolomic Biomarkers (Conference Paper)

    Kenny, L. C., Broadhurst, D. I., Dunn, W., Brown, M., North, R. A., Cooper, G. J. S., . . . Baker, P. N. (2009). Early Pregnancy Prediction of Preeclampsia Using Metabolomic Biomarkers. In REPRODUCTIVE SCIENCES Vol. 16 (pp. 102A). Retrieved from http://gateway.webofknowledge.com/

    Metabolic Footprinting of Preeclamptic Placental Tissue Using UPLC/LTQ-Orbitrap Mass Spectrometry (Conference Paper)

    Brown, M., Heazell, A., Dunn, W. B., Kenny, L. C., Broadhurst, D. I., Horgan, R., . . . Baker, P. N. (2009). Metabolic Footprinting of Preeclamptic Placental Tissue Using UPLC/LTQ-Orbitrap Mass Spectrometry. In REPRODUCTIVE SCIENCES Vol. 16 (pp. 342A). Retrieved from http://gateway.webofknowledge.com/

    Opinion (Journal article)

    Kell, D. (2009). Opinion. Food Science and Technology, 23(1), 17.

    Scientific Abstracts (Journal article)

    Scientific Abstracts (2009). Reproductive Sciences, 16(3_suppl), 67A-374A. doi:10.1177/193371912009163s167

    DOI: 10.1177/193371912009163s167

    Development of a Robust and Repeatable UPLC-MS Method for the Long-Term Metabolomic Study of Human Serum (Journal article)

    Zelena, E., Dunn, W. B., Broadhurst, D., Francis-McIntyre, S., Carroll, K. M., Begley, P., . . . Consortium, H. U. S. E. R. M. E. T. (2009). Development of a Robust and Repeatable UPLC-MS Method for the Long-Term Metabolomic Study of Human Serum. ANALYTICAL CHEMISTRY, 81(4), 1357-1364. doi:10.1021/ac8019366

    DOI: 10.1021/ac8019366

    Anaesthetic function (Journal article)

    Kell, D. (2009). Anaesthetic function. NEW SCIENTIST, 201(2694), 27. doi:10.1016/S0262-4079(09)60363-8

    DOI: 10.1016/S0262-4079(09)60363-8

    Implications of the Dominant Role of Transporters in Drug Uptake by Cells (Journal article)

    Dobson, P. D., Lanthaler, K., Oliver, S. G., & Kell, D. B. (2009). Implications of the Dominant Role of Transporters in Drug Uptake by Cells. CURRENT TOPICS IN MEDICINAL CHEMISTRY, 9(2), 163-181. doi:10.2174/156802609787521616

    DOI: 10.2174/156802609787521616

    Array-based evolution of DNA aptamers allows modelling of an explicit sequence-fitness landscape (Journal article)

    Knight, C. G., Platt, M., Rowe, W., Wedge, D. C., Khan, F., Day, P. J. R., . . . Kell, D. B. (2009). Array-based evolution of DNA aptamers allows modelling of an explicit sequence-fitness landscape. NUCLEIC ACIDS RESEARCH, 37(1). doi:10.1093/nar/gkn899

    DOI: 10.1093/nar/gkn899

    Iron behaving badly: inappropriate iron chelation as a major contributor to the aetiology of vascular and other progressive inflammatory and degenerative diseases (Journal article)

    Kell, D. B. (2009). Iron behaving badly: inappropriate iron chelation as a major contributor to the aetiology of vascular and other progressive inflammatory and degenerative diseases. BMC MEDICAL GENOMICS, 2. doi:10.1186/1755-8794-2-2

    DOI: 10.1186/1755-8794-2-2

    'Metabolite-likeness' as a criterion in the design and selection of pharmaceutical drug libraries (Journal article)

    Dobson, P. D., Patel, Y., & Kell, D. B. (2009). 'Metabolite-likeness' as a criterion in the design and selection of pharmaceutical drug libraries. DRUG DISCOVERY TODAY, 14(1-2), 31-40. doi:10.1016/j.drudis.2008.10.011

    DOI: 10.1016/j.drudis.2008.10.011

    Mass spectrometry tools and metabolite-specific databases for molecular identification in metabolomics (Journal article)

    Brown, M., Dunn, W. B., Dobson, P., Patel, Y., Winder, C. L., Francis-McIntyre, S., . . . Kell, D. B. (2009). Mass spectrometry tools and metabolite-specific databases for molecular identification in metabolomics. ANALYST, 134(7), 1322-1332. doi:10.1039/b901179j

    DOI: 10.1039/b901179j

    2008

    Rapid prediction of optimum population size in genetic programming using a novel genotype - Fitness correlation (Conference Paper)

    Wedge, D. C., & Kell, D. B. (2008). Rapid prediction of optimum population size in genetic programming using a novel genotype - Fitness correlation. In GECCO'08: Proceedings of the 10th Annual Conference on Genetic and Evolutionary Computation 2008 (pp. 1315-1322).

    Q&A (Journal article)

    Kell, P. D., & Reece, R. (2008). Q&A. The Biochemist, 30(6), 31-32. doi:10.1042/bio03006031

    DOI: 10.1042/bio03006031

    Molecular Structure Elucidation Using Ant Colony Optimization: A Preliminary Study (Conference Paper)

    Farrelly, C., Kell, D. B., & Knowles, J. (2008). Molecular Structure Elucidation Using Ant Colony Optimization: A Preliminary Study. In ANT COLONY OPTIMIZATION AND SWARM INTELLIGENCE, PROCEEDINGS Vol. 5217 (pp. 120-131). Retrieved from http://gateway.webofknowledge.com/

    Progress being made on standards for use in data sharing (Journal article)

    Kell, D. B. (2008). Progress being made on standards for use in data sharing. NATURE, 456(7218), 29. doi:10.1038/456029c

    DOI: 10.1038/456029c

    Sensitivity Analysis and Robust Experimental Design of a Signal Transduction Pathway System (Conference Paper)

    Yue, H., Brown, M., He, F., Jia, J., & Kell, D. B. (2008). Sensitivity Analysis and Robust Experimental Design of a Signal Transduction Pathway System. In INTERNATIONAL JOURNAL OF CHEMICAL KINETICS Vol. 40 (pp. 730-741). doi:10.1002/kin.20369

    DOI: 10.1002/kin.20369

    Defrosting the Digital Library: Bibliographic Tools for the Next Generation Web (Journal article)

    Hull, D., Pettifer, S. R., & Kell, D. B. (2008). Defrosting the Digital Library: Bibliographic Tools for the Next Generation Web. PLOS COMPUTATIONAL BIOLOGY, 4(10). doi:10.1371/journal.pcbi.1000204

    DOI: 10.1371/journal.pcbi.1000204

    A consensus yeast metabolic network reconstruction obtained from a community approach to systems biology (Journal article)

    Herrgard, M. J., Swainston, N., Dobson, P., Dunn, W. B., Arga, K. Y., Arvas, M., . . . Kell, D. B. (2008). A consensus yeast metabolic network reconstruction obtained from a community approach to systems biology. NATURE BIOTECHNOLOGY, 26(10), 1155-1160. doi:10.1038/nbt1492

    DOI: 10.1038/nbt1492

    Metabolic profiling of serum using Ultra Performance Liquid Chromatography and the LTQ-Orbitrap mass spectrometry system (Journal article)

    Dunn, W. B., Broadhurst, D., Brown, M., Baker, P. N., Redman, C. W. G., Kenny, L. C., & Kell, D. B. (2008). Metabolic profiling of serum using Ultra Performance Liquid Chromatography and the LTQ-Orbitrap mass spectrometry system. JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 871(2), 288-298. doi:10.1016/j.jchromb.2008.03.021

    DOI: 10.1016/j.jchromb.2008.03.021

    Performing statistical analyses on quantitative data in Taverna workflows: An example using R and maxdBrowse to identify differentially-expressed genes from microarray data (Journal article)

    Li, P., Castrillo, J. I., Velarde, G., Wassink, I., Soiland-Reyes, S., Owen, S., . . . Kell, D. B. (2008). Performing statistical analyses on quantitative data in Taverna workflows: An example using R and maxdBrowse to identify differentially-expressed genes from microarray data. BMC BIOINFORMATICS, 9. doi:10.1186/1471-2105-9-334

    DOI: 10.1186/1471-2105-9-334

    Analysis of the metabolic footprint and tissue metabolome of placental villous explants cultured at different oxygen tensions reveals novel redox biomarkers (Journal article)

    Heazell, A. E. P., Brown, M., Dunn, W. B., Worton, S. A., Crocker, I. P., Baker, P. N., & Kell, D. B. (2008). Analysis of the metabolic footprint and tissue metabolome of placental villous explants cultured at different oxygen tensions reveals novel redox biomarkers. PLACENTA, 29(8), 691-698. doi:10.1016/j.placenta.2008.05.002

    DOI: 10.1016/j.placenta.2008.05.002

    Metabolomic investigation of placental factors released in pre-eclampsia (Conference Paper)

    Worlon, S. A., Brown, M., Dunn, W. B., Crocker, I. P., Baker, P. N., Kell, D. B., & Heazell, A. E. P. (2008). Metabolomic investigation of placental factors released in pre-eclampsia. In PLACENTA Vol. 29 (pp. A76). Retrieved from http://gateway.webofknowledge.com/

    Detection and identification of novel metabolomic biomarkers in preeclampsia (Journal article)

    Kenny, L. C., Broadhurst, D., Brown, M., Dunn, W. B., Redman, C. W. G., Kill, D. B., & Baker, P. N. (2008). Detection and identification of novel metabolomic biomarkers in preeclampsia. REPRODUCTIVE SCIENCES, 15(6), 591-597. doi:10.1177/1933719108316908

    DOI: 10.1177/1933719108316908

    The markup is the model: Reasoning about systems biology models in the Semantic Web era (Journal article)

    Kell, D. B., & Mendes, P. (2008). The markup is the model: Reasoning about systems biology models in the Semantic Web era. JOURNAL OF THEORETICAL BIOLOGY, 252(3), 538-543. doi:10.1016/j.jtbi.2007.10.023

    DOI: 10.1016/j.jtbi.2007.10.023

    Bayesian inference of the sites of perturbations in metabolic pathways via Markov chain Monte Carlo (Journal article)

    Jayawardhana, B., Kell, D. B., & Rattray, M. (2008). Bayesian inference of the sites of perturbations in metabolic pathways via Markov chain Monte Carlo. BIOINFORMATICS, 24(9), 1191-1197. doi:10.1093/bioinformatics/btn103

    DOI: 10.1093/bioinformatics/btn103

    Facilitating the development of controlled vocabularies for metabolomics technologies with text mining (Journal article)

    Spasic, I., Schober, D., Sansone, S. -A., Rebholz-Schuhmann, D., Kell, D. B., & Paton, N. W. (2008). Facilitating the development of controlled vocabularies for metabolomics technologies with text mining. BMC BIOINFORMATICS, 9. doi:10.1186/1471-2105-9-S5-S5

    DOI: 10.1186/1471-2105-9-S5-S5

    A GC-TOF-MS study of the stability of serum and urine metabolomes during the UK Biobank sample collection and preparation protocols (Journal article)

    Dunn, W. B., Broadhurst, D., Ellis, D. I., Brown, M., Halsall, A., O'Hagan, S., . . . Kell, D. B. (2008). A GC-TOF-MS study of the stability of serum and urine metabolomes during the UK Biobank sample collection and preparation protocols. INTERNATIONAL JOURNAL OF EPIDEMIOLOGY, 37, 23-30. doi:10.1093/ije/dym281

    DOI: 10.1093/ije/dym281

    Comparative evaluation of software for deconvolution of metabolomics data based on GC-TOF-MS (Journal article)

    Lu, H., Dunn, W. B., Shen, H., Kell, D. B., & Liang, Y. (2008). Comparative evaluation of software for deconvolution of metabolomics data based on GC-TOF-MS. TRAC-TRENDS IN ANALYTICAL CHEMISTRY, 27(3), 215-227. doi:10.1016/j.trac.2007.11.004

    DOI: 10.1016/j.trac.2007.11.004

    Metabolite profiles of interacting mycelial fronts differ for pairings of the wood decay basidiomycete fungus, Stereum hirsutum with its competitors Coprinus micaceus and Coprinus disseminatus (Journal article)

    Peiris, D., Dunn, W. B., Brown, M., Kell, D. B., Roy, I., & Hedger, J. N. (2008). Metabolite profiles of interacting mycelial fronts differ for pairings of the wood decay basidiomycete fungus, Stereum hirsutum with its competitors Coprinus micaceus and Coprinus disseminatus. METABOLOMICS, 4(1), 52-62. doi:10.1007/s11306-007-0100-4

    DOI: 10.1007/s11306-007-0100-4

    Opinion - Carrier-mediated cellular uptake of pharmaceutical drugs: an exception or the rule? (Journal article)

    Dobson, P. D., & Kell, D. B. (2008). Opinion - Carrier-mediated cellular uptake of pharmaceutical drugs: an exception or the rule?. NATURE REVIEWS DRUG DISCOVERY, 7(3), 205-220. doi:10.1038/nrd2438

    DOI: 10.1038/nrd2438

    Information-theoretic sensitivity analysis: a general method for credit assignment in complex networks (Journal article)

    Luedtke, N., Panzeri, S., Brown, M., Broomhead, D. S., Knowles, J., Montemurro, M. A., & Kell, D. B. (2008). Information-theoretic sensitivity analysis: a general method for credit assignment in complex networks. JOURNAL OF THE ROYAL SOCIETY INTERFACE, 5(19), 223-235. doi:10.1098/rsif.2007.1079

    DOI: 10.1098/rsif.2007.1079

    Changes in metabolic profile of placental villous explants cultured in different oxygen tensions. (Conference Paper)

    Heazell, A. E., Brown, M. C., Dunn, W. B., Worton, S. A., Robinson, N., Baker, P. N., & Kell, D. B. (2008). Changes in metabolic profile of placental villous explants cultured in different oxygen tensions.. In REPRODUCTIVE SCIENCES Vol. 15 (pp. 318A). Retrieved from http://gateway.webofknowledge.com/

    Metabolic footprinting of placental explants using UPLC/LTQ-Orbitrap mass spectrometry. (Conference Paper)

    Brown, M., Heazell, A., Dunn, W. B., Kenny, L. C., Worton, S., Kell, D. B., & Baker, P. N. (2008). Metabolic footprinting of placental explants using UPLC/LTQ-Orbitrap mass spectrometry.. In REPRODUCTIVE SCIENCES Vol. 15 (pp. 318A). Retrieved from http://gateway.webofknowledge.com/

    The application of UPLC/LTQ-Orbitrap mass Spectrometry to human metabolite biomarker discovery. A case study: Pre-eclampsia. (Conference Paper)

    Broadhurst, D. I., Brown, M., Dunn, W. B., Carroll, K. B., Redman, C. W., Baker, P. N., . . . Kenny, L. C. (2008). The application of UPLC/LTQ-Orbitrap mass Spectrometry to human metabolite biomarker discovery. A case study: Pre-eclampsia.. In REPRODUCTIVE SCIENCES Vol. 15 (pp. 208A). Retrieved from http://gateway.webofknowledge.com/

    Automated manipulation of systems biology models using libSBML within Taverna workflows (Journal article)

    Li, P., Oinn, T., Soiland, S., & Kell, D. B. (2008). Automated manipulation of systems biology models using libSBML within Taverna workflows. BIOINFORMATICS, 24(2), 287-289. doi:10.1093/bioinformatics/btm578

    DOI: 10.1093/bioinformatics/btm578

    Identification and characterization of high-flux-control genes of yeast through competition analyses in continuous cultures (Journal article)

    Delneri, D., Hoyle, D. C., Gkargkas, K., Cross, E. J. M., Rash, B., Zeef, L., . . . Oliver, S. G. (2008). Identification and characterization of high-flux-control genes of yeast through competition analyses in continuous cultures. NATURE GENETICS, 40(1), 113-117. doi:10.1038/ng.2007.49

    DOI: 10.1038/ng.2007.49

    The landscape adaptive particle swarm optimizer (Journal article)

    Yisu, J., Knowles, J., Hongmei, L., Liang, Y., & Kell, D. B. (2008). The landscape adaptive particle swarm optimizer. APPLIED SOFT COMPUTING, 8(1), 295-304. doi:10.1016/j.asoc.2007.01.009

    DOI: 10.1016/j.asoc.2007.01.009

    2007

    Improving Data Fitting of a Signal Transduction Model by Global Sensitivity Analysis (Conference Paper)

    Jin, Y., Yue, H., Brown, M., Liang, Y., & Kell, D. B. (2007). Improving Data Fitting of a Signal Transduction Model by Global Sensitivity Analysis. In 2007 American Control Conference. IEEE. doi:10.1109/acc.2007.4282366

    DOI: 10.1109/acc.2007.4282366

    Taverna/myGrid: Aligning a Workflow System with the Life Sciences Community (Chapter)

    Oinn, T., Li, P., Kell, D. B., Goble, C., Goderis, A., Greenwood, M., . . . Zhao, J. (n.d.). Taverna/myGrid: Aligning a Workflow System with the Life Sciences Community. In Workflows for e-Science (pp. 300-319). Springer London. doi:10.1007/978-1-84628-757-2_19

    DOI: 10.1007/978-1-84628-757-2_19

    The methodologies of systems biology (Chapter)

    Westerhoff, H. V., & Kell, D. B. (2007). The methodologies of systems biology. In Systems Biology (pp. 23-70). Elsevier. doi:10.1016/b978-044452085-2/50004-8

    DOI: 10.1016/b978-044452085-2/50004-8

    Serum metabolomics reveals many novel metabolic markers of heart failure, including pseudouridine and 2-oxoglutarate (Journal article)

    Dunn, W. B., Broadhurst, D. I., Deepak, S. M., Buch, M. H., McDowell, G., Spasic, I., . . . Neyses, L. (2007). Serum metabolomics reveals many novel metabolic markers of heart failure, including pseudouridine and 2-oxoglutarate. METABOLOMICS, 3(4), 413-426. doi:10.1007/s11306-007-0063-5

    DOI: 10.1007/s11306-007-0063-5

    The virtual human: Towards a global systems biology of multiscale, distributed biochemical network models (Journal article)

    Kell, D. B. (2007). The virtual human: Towards a global systems biology of multiscale, distributed biochemical network models. IUBMB LIFE, 59(11), 689-695. doi:10.1080/15216540701694252

    DOI: 10.1080/15216540701694252

    Something from nothing - bridging the gap between constraint-based and kinetic modelling (Journal article)

    Smallbone, K., Simeonidis, E., Broomhead, D. S., & Kell, D. B. (2007). Something from nothing - bridging the gap between constraint-based and kinetic modelling. FEBS JOURNAL, 274(21), 5576-5585. doi:10.1111/j.1742-4658.2007.06076.x

    DOI: 10.1111/j.1742-4658.2007.06076.x

    Proposed minimum reporting standards for data analysis in metabolomics (Journal article)

    Goodacre, R., Broadhurst, D., Smilde, A. K., Kristal, B. S., Baker, J. D., Beger, R., . . . Wulfert, F. (2007). Proposed minimum reporting standards for data analysis in metabolomics. METABOLOMICS, 3(3), 231-241. doi:10.1007/s11306-007-0081-3

    DOI: 10.1007/s11306-007-0081-3

    Transcriptional and metabolic response of Saccharomyces cerevisiae to a nutritional perturbation when under stress (Conference Paper)

    Dikicioglu, D., Rash, B., Dunn, W. B., Pir, P., Hayes, A., Kell, D. B., . . . Oliver, S. G. (2007). Transcriptional and metabolic response of Saccharomyces cerevisiae to a nutritional perturbation when under stress. In JOURNAL OF BIOTECHNOLOGY Vol. 131 (pp. S14-S15). doi:10.1016/j.jbiotec.2007.07.028

    DOI: 10.1016/j.jbiotec.2007.07.028

    Peptide Detectability following ESI Mass Spectrometry: Prediction using Genetic Programming (Conference Paper)

    Wedge, D. C., Kell, D. B., Gaskell, S. J., Lau, K. W., Hubbard, S. J., Eyers, C., & ACM. (2007). Peptide Detectability following ESI Mass Spectrometry: Prediction using Genetic Programming. In GECCO 2007: GENETIC AND EVOLUTIONARY COMPUTATION CONFERENCE, VOL 1 AND 2 (pp. 2219-+). Retrieved from http://gateway.webofknowledge.com/

    Metabolic footprinting as a tool for discriminating between brewing yeasts (Journal article)

    Pope, G. A., MacKenzie, D. A., Defemez, M., Aroso, M. A. M. M., Fuller, L. J., Mellon, F. A., . . . Roberts, I. N. (2007). Metabolic footprinting as a tool for discriminating between brewing yeasts. YEAST, 24(8), 667-679. doi:10.1002/yea.1499

    DOI: 10.1002/yea.1499

    Metabolomic biomarkers: search, discovery and validation (Journal article)

    Kell, D. B. (2007). Metabolomic biomarkers: search, discovery and validation. EXPERT REVIEW OF MOLECULAR DIAGNOSTICS, 7(4), 329-333. doi:10.1586/14737159.7.4.329

    DOI: 10.1586/14737159.7.4.329

    Serum metabolomic analysis successfully discriminates heart failure patients from controls (Conference Paper)

    Deepak, S., Dunn, W., Broadhurst, D., Buch, M., McDowell, G., Ellis, D., . . . Neyses, L. (2007). Serum metabolomic analysis successfully discriminates heart failure patients from controls. In HEART Vol. 93 (pp. A78-A79). Retrieved from http://gateway.webofknowledge.com/

    Growth control of the eukaryote cell: a systems biology study in yeast. (Journal article)

    Castrillo, J. I., Zeef, L. A., Hoyle, D. C., Zhang, N., Hayes, A., Gardner, D. C., . . . Oliver, S. G. (2007). Growth control of the eukaryote cell: a systems biology study in yeast.. Journal of biology, 6(2), 4. doi:10.1186/jbiol54

    DOI: 10.1186/jbiol54

    Multiobjective optimization in bioinformatics and computational biology (Journal article)

    Handl, J., Kell, D. B., & Knowles, J. (2007). Multiobjective optimization in bioinformatics and computational biology. IEEE-ACM TRANSACTIONS ON COMPUTATIONAL BIOLOGY AND BIOINFORMATICS, 4(2), 279-292. doi:10.1109/TCBB.2007.070203

    DOI: 10.1109/TCBB.2007.070203

    Closed-loop, multiobjective optimization of two-dimensional gas chromatography/mass spectrometry for serum metabolomics (Journal article)

    Hagan, S. O., Dunn, W. B., Knowles, J. D., Broadhurst, D., Williams, R., Ashworth, J. J., . . . Kell, D. B. (2007). Closed-loop, multiobjective optimization of two-dimensional gas chromatography/mass spectrometry for serum metabolomics. ANALYTICAL CHEMISTRY, 79(2), 464-476. doi:10.1021/ac061443+

    DOI: 10.1021/ac061443+

    Statistical strategies for avoiding false discoveries in metabolomics and related experiments (Journal article)

    Broadhurst, D. I., & Kell, D. B. (2006). Statistical strategies for avoiding false discoveries in metabolomics and related experiments. METABOLOMICS, 2(4), 171-196. doi:10.1007/s11306-006-0037-z

    DOI: 10.1007/s11306-006-0037-z

    Impaired endothelium-dependent vascular reactivity in patients with familial combined hyperlipidaemia. (Journal article)

    De Michele, M., Iannuzzi, A., Salvato, A., Pauciullo, P., Gentile, M., Iannuzzo, G., . . . Rubba, P. (2007). Impaired endothelium-dependent vascular reactivity in patients with familial combined hyperlipidaemia.. Heart (British Cardiac Society), 93(1), 78-81. doi:10.1136/hrt.2006.093278

    DOI: 10.1136/hrt.2006.093278

    Improving data fitting of a signal transduction model by global sensitivity analysis (Conference Paper)

    Jin, Y., Yue, H., Brown, M., Liang, Y., Kell, D. B., & IEEE. (2007). Improving data fitting of a signal transduction model by global sensitivity analysis. In 2007 AMERICAN CONTROL CONFERENCE, VOLS 1-13 (pp. 1379-1384). Retrieved from http://gateway.webofknowledge.com/

    Proximate parameter tuning for biochemical networks with uncertain kinetic parameters (Journal article)

    Wilkinson, S. J., Benson, N., & Kell, D. B. (2008). Proximate parameter tuning for biochemical networks with uncertain kinetic parameters. MOLECULAR BIOSYSTEMS, 4(1), 74-97. doi:10.1039/b707506e

    DOI: 10.1039/b707506e

    2006

    Automated tracking of gene expression in individual cells and cell compartments (Journal article)

    Shen, H., Nelson, G., Nelson, D. E., Kennedy, S., Spiller, D. G., Griffiths, T., . . . Kell, D. B. (2006). Automated tracking of gene expression in individual cells and cell compartments. JOURNAL OF THE ROYAL SOCIETY INTERFACE, 3(11), 787-794. doi:10.1098/rsif.2006.0137

    DOI: 10.1098/rsif.2006.0137

    Systems biology, metabolic modelling and metabolomics in drug discovery and development (Journal article)

    Kell, D. B. (2006). Systems biology, metabolic modelling and metabolomics in drug discovery and development. DRUG DISCOVERY TODAY, 11(23-24), 1085-1092. doi:10.1016/j.drudis.2006.10.004

    DOI: 10.1016/j.drudis.2006.10.004

    Text mining and its potential applications in systems biology (Journal article)

    Ananiadou, S., Kell, D. B., & Tsujii, J. -I. (2006). Text mining and its potential applications in systems biology. TRENDS IN BIOTECHNOLOGY, 24(12), 571-579. doi:10.1016/j.tibtech.2006.10.002

    DOI: 10.1016/j.tibtech.2006.10.002

    Insights into the behaviour of systems biology models from dynamic sensitivty and identifiability analysis: a case study of an NF-kappa B signalling pathway (Journal article)

    Yue, H., Brown, M., Knowles, J., Wang, H., Broomhead, D. S., & Kell, D. B. (2006). Insights into the behaviour of systems biology models from dynamic sensitivty and identifiability analysis: a case study of an NF-kappa B signalling pathway. MOLECULAR BIOSYSTEMS, 2(12), 640-649. doi:10.1039/b609442b

    DOI: 10.1039/b609442b

    MeMo: a hybrid SQL/XML approach to metabolomic data management for functional genomics (Journal article)

    Spasic, I., Dunn, W. B., Velarde, G., Tseng, A., Jenkins, H., Hardy, N., . . . Kell, D. B. (2006). MeMo: a hybrid SQL/XML approach to metabolomic data management for functional genomics. BMC BIOINFORMATICS, 7. doi:10.1186/1471-2105-7-281

    DOI: 10.1186/1471-2105-7-281

    Metabolomics: The new science of metabolic integration (Conference Paper)

    Kell, D. B. (2006). Metabolomics: The new science of metabolic integration. In JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY Vol. 40 (pp. 935). doi:10.1016/j.yjmcc.2006.03.055

    DOI: 10.1016/j.yjmcc.2006.03.055

    Automatic tracking of biological cells and compartments using particle filters and active contours (Journal article)

    Shen, H., Nelson, G., Kennedy, S., Nelson, D., Johnson, J., Spiller, D., . . . Kell, D. B. (2006). Automatic tracking of biological cells and compartments using particle filters and active contours. CHEMOMETRICS AND INTELLIGENT LABORATORY SYSTEMS, 82(1-2), 276-282. doi:10.1016/j.chemolab.2005.07.007

    DOI: 10.1016/j.chemolab.2005.07.007

    Huntington disease patients and transgenic mice have similar pro-catabolic serum metabolite profiles (Journal article)

    Underwood, B. R., Broadhurst, D., Dunn, W. B., Ellis, D. I., Michell, A. W., Vacher, C., . . . Rubinsztein, D. C. (2006). Huntington disease patients and transgenic mice have similar pro-catabolic serum metabolite profiles. BRAIN, 129, 877-886. doi:10.1093/brain/awl027

    DOI: 10.1093/brain/awl027

    Metabolomics, modelling and machine learning in systems biology - towards an understanding of the languages of cells (Conference Paper)

    Kell, D. B. (2006). Metabolomics, modelling and machine learning in systems biology - towards an understanding of the languages of cells. In FEBS JOURNAL Vol. 273 (pp. 873-894). doi:10.1111/j.1742-4658.2006.05136.x

    DOI: 10.1111/j.1742-4658.2006.05136.x

    Rapid high-throughput detection of preeclampsia. (Conference Paper)

    Kenny, L. C., Harding, K. E. L., Ellis, D. I., Broadhurst, D., Dunn, W. B., Kell, D. B., & Baker, P. N. (2006). Rapid high-throughput detection of preeclampsia.. In JOURNAL OF THE SOCIETY FOR GYNECOLOGIC INVESTIGATION Vol. 13 (pp. 124A-125A). Retrieved from http://gateway.webofknowledge.com/

    Muralytic activity of Micrococcus luteus Rpf and its relationship to physiological activity in promoting bacterial growth and resuscitation (Journal article)

    Mukamolova, G. V., Murzin, A. G., Salina, E. G., Demina, G. R., Kell, D. B., Kaprelyants, A. S., & Young, M. (2006). Muralytic activity of Micrococcus luteus Rpf and its relationship to physiological activity in promoting bacterial growth and resuscitation. MOLECULAR MICROBIOLOGY, 59(1), 84-98. doi:10.1111/j.1365-2958.2005.04930.x

    DOI: 10.1111/j.1365-2958.2005.04930.x

    2005

    maxdLoad2 and maxdBrowse: standards-compliant tools for microarray experimental annotation, data management and dissemination (Journal article)

    Hancock, D., Wilson, M., Velarde, G., Morrison, N., Hayes, A., Hulme, H., . . . Brass, A. (2005). maxdLoad2 and maxdBrowse: standards-compliant tools for microarray experimental annotation, data management and dissemination. BMC BIOINFORMATICS, 6. doi:10.1186/1471-2105-6-264

    DOI: 10.1186/1471-2105-6-264

    Hierarchical metabolomics demonstrates substantial compositional similarity between genetically modified and conventional potato crops (Journal article)

    Catchpole, G. S., Beckmann, M., Enot, D. P., Mondhe, M., Zywicki, B., Taylor, J., . . . Draper, J. (2005). Hierarchical metabolomics demonstrates substantial compositional similarity between genetically modified and conventional potato crops. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 102(40), 14458-14462. doi:10.1073/pnas.0503955102

    DOI: 10.1073/pnas.0503955102

    Synergistic control of oscillations in the NF-kappa B signalling pathway (Journal article)

    Ihekwaba, A. E. C., Broomhead, D. S., Grimley, R., Benson, N., White, M. R. H., & Kell, D. B. (2005). Synergistic control of oscillations in the NF-kappa B signalling pathway. IEE PROCEEDINGS SYSTEMS BIOLOGY, 152(3), 153-160. doi:10.1049/ip-syb:20050050

    DOI: 10.1049/ip-syb:20050050

    Computational cluster validation in post-genomic data analysis (Journal article)

    Handl, J., Knowles, J., & Kell, D. B. (2005). Computational cluster validation in post-genomic data analysis. BIOINFORMATICS, 21(15), 3201-3212. doi:10.1093/bioinformatics/bti517

    DOI: 10.1093/bioinformatics/bti517

    Metabolomics, machine learning and modelling in systems biology: Towards an understanding of the language of cells (Conference Paper)

    Kell, D. B. (2005). Metabolomics, machine learning and modelling in systems biology: Towards an understanding of the language of cells. In JOURNAL OF BIOTECHNOLOGY Vol. 118 (pp. S5). Retrieved from http://gateway.webofknowledge.com/

    A laser desorption ionisation mass spectrometry approach for high throughput metabolomics (Journal article)

    Vaidyanathan, S., Jones, D., Broadhurst, D. I., Ellis, J., Jenkins, T., Dunn, W. B., . . . Goodacre, R. (2005). A laser desorption ionisation mass spectrometry approach for high throughput metabolomics. METABOLOMICS, 1(3), 243-250. doi:10.1007/s11306-005-0007-x

    DOI: 10.1007/s11306-005-0007-x

    Metabolic footprinting and systems biology: The medium is the message (Journal article)

    Kell, D. B., Brown, M., Davey, H. M., Dunn, W. B., Spasic, I., & Oliver, S. G. (2005). Metabolic footprinting and systems biology: The medium is the message. NATURE REVIEWS MICROBIOLOGY, 3(7), 557-565. doi:10.1038/nrmicro1177

    DOI: 10.1038/nrmicro1177

    Metabolic footprinting and systems biology: the medium is the message. (Journal article)

    Kell, D. B., Brown, M., Davey, H. M., Dunn, W. B., Spasic, I., & Oliver, S. G. (2005). Metabolic footprinting and systems biology: the medium is the message.. Nature reviews. Microbiology, 3(7), 557-565. doi:10.1038/nrmicro1177

    DOI: 10.1038/nrmicro1177

    Metabolomics, modelling and machine learning in systems biology; understanding complex systems using genetic programming to produce simple interpretable rules. The Theodor Bucher Lecture and Medal (Conference Paper)

    Kell, D. B. (2005). Metabolomics, modelling and machine learning in systems biology; understanding complex systems using genetic programming to produce simple interpretable rules. The Theodor Bucher Lecture and Medal. In FEBS JOURNAL Vol. 272 (pp. 2). Retrieved from http://gateway.webofknowledge.com/

    Novel biomarkers for pre-eclampsia detected using metabolomics and machine learning (Journal article)

    Kenny, L. C., Dunn, W. B., Ellis, D. I., Myers, J., Baker, P. N., Kell, D. B., & Consortium, G. O. P. E. C. (2005). Novel biomarkers for pre-eclampsia detected using metabolomics and machine learning. METABOLOMICS, 1(3), 227-234. doi:10.1007/s11306-005-0003-1

    DOI: 10.1007/s11306-005-0003-1

    A general model of error-prone PCR (Journal article)

    Pritchard, L., Corne, D., Kell, D., Rowland, J., & Winson, M. (2005). A general model of error-prone PCR. JOURNAL OF THEORETICAL BIOLOGY, 234(4), 497-509. doi:10.1016/j.jtbi.2004.12.005

    DOI: 10.1016/j.jtbi.2004.12.005

    Metabolomics, machine learning and modelling: towards an understanding of the language of cells (Journal article)

    Kell, D. B. (2005). Metabolomics, machine learning and modelling: towards an understanding of the language of cells. BIOCHEMICAL SOCIETY TRANSACTIONS, 33, 520-524. doi:10.1042/BST0330520

    DOI: 10.1042/BST0330520

    Response to Comment on "Oscillations in NF-kappa B signaling control the dynamics of gene expression" (Journal article)

    Nelson, D. E., Horton, C. A., See, V., Johnson, J. R., Nelson, G., Spiller, D. G., . . . White, M. R. H. (2005). Response to Comment on "Oscillations in NF-kappa B signaling control the dynamics of gene expression". SCIENCE, 308(5718). doi:10.1126/science.1108198

    DOI: 10.1126/science.1108198

    Electrospray-ionization mass spectrometry of protein mixtures: Influence of instrumental settings and proteomic implications. (Conference Paper)

    Vaidyanathan, S., Kell, D. B., & Goodacre, R. (2005). Electrospray-ionization mass spectrometry of protein mixtures: Influence of instrumental settings and proteomic implications.. In ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY Vol. 229 (pp. U185). Retrieved from http://gateway.webofknowledge.com/

    Metabolomic investigations using laser desorption ionisation mass spectrometry on porous silicon (Conference Paper)

    Vaidyanathan, S., Jones, D., Jenkins, T., Kell, D. B., & Goodacre, R. (2005). Metabolomic investigations using laser desorption ionisation mass spectrometry on porous silicon. In ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY Vol. 229 (pp. U245). Retrieved from http://gateway.webofknowledge.com/

    A metabolome pipeline: from concept to data to knowledge (Journal article)

    Brown, M., Dunn, W. B., Ellis, D. I., Goodacre, R., Handl, J., Knowles, J. D., . . . Kell, D. B. (2005). A metabolome pipeline: from concept to data to knowledge. METABOLOMICS, 1(1), 39-51. doi:10.1007/s11306-005-1106-4

    DOI: 10.1007/s11306-005-1106-4

    Alterations in placental hemodynamics in growth-restricted transgenic mice. (Conference Paper)

    Kenny, L. C., Dunn, W. B., Ellis, D. I., Myers, J. E., Robinson, A. E., Kell, D. B., & Baker, P. N. (2005). Alterations in placental hemodynamics in growth-restricted transgenic mice.. In JOURNAL OF THE SOCIETY FOR GYNECOLOGIC INVESTIGATION Vol. 12 (pp. 199A). Retrieved from http://gateway.webofknowledge.com/

    Novel biomarkers for preeclampsia detected using metabolomics and machine learning. (Conference Paper)

    Kenny, L. C., Dunn, W. B., Ellis, D. I., Myers, J. E., Robinson, A. E., Kell, D. B., & Baker, P. N. (2005). Novel biomarkers for preeclampsia detected using metabolomics and machine learning.. In JOURNAL OF THE SOCIETY FOR GYNECOLOGIC INVESTIGATION Vol. 12 (pp. 199A). Retrieved from http://gateway.webofknowledge.com/

    Vacuum packing: a model system for laboratory-scale silage fermentations (Journal article)

    Johnson, H. E., Merry, R. J., Davies, D. R., Kell, D. B., Theodorou, M. K., & Griffith, G. W. (2005). Vacuum packing: a model system for laboratory-scale silage fermentations. JOURNAL OF APPLIED MICROBIOLOGY, 98(1), 106-113. doi:10.1111/j.1365-2672.2004.02444.x

    DOI: 10.1111/j.1365-2672.2004.02444.x

    Closed-loop, multiobjective optimization of analytical instrumentation: Gas chromatography/time-of-flight mass spectrometry of the metabolomes of human serum and of yeast fermentations (Journal article)

    O'Hagan, S., Dunn, W. B., Brown, M., Knowles, J. D., & Kell, D. B. (2005). Closed-loop, multiobjective optimization of analytical instrumentation: Gas chromatography/time-of-flight mass spectrometry of the metabolomes of human serum and of yeast fermentations. ANALYTICAL CHEMISTRY, 77(1), 290-303. doi:10.1021/ac049146x

    DOI: 10.1021/ac049146x

    DOUGLAS KELL COMMENTS ON 'METHODOLOGY' DURING THE WORKSHOP. (Conference Paper)

    Kell, D. B. (2005). DOUGLAS KELL COMMENTS ON 'METHODOLOGY' DURING THE WORKSHOP.. In NONLINEAR DIELECTRIC PHENOMENA IN COMPLEX LIQUIDS Vol. 157 (pp. 61). doi:10.1007/1-4020-2704-4_7

    DOI: 10.1007/1-4020-2704-4_7

    NONLINEAR DIELECTRIC SPECTROSCOPY OF BIOLOGICAL SYSTEMS: PRINCIPLES AND APPLICATIONS (Conference Paper)

    Kell, D. B., Woodward, A. M., Davies, E. A., Todd, R. W., Evans, M. F., & Rowland, J. J. (2005). NONLINEAR DIELECTRIC SPECTROSCOPY OF BIOLOGICAL SYSTEMS: PRINCIPLES AND APPLICATIONS. In NONLINEAR DIELECTRIC PHENOMENA IN COMPLEX LIQUIDS Vol. 157 (pp. 335-344). doi:10.1007/1-4020-2704-4_31

    DOI: 10.1007/1-4020-2704-4_31

    2004

    A proposed framework for the description of plant metabolomics experiments and their results (Journal article)

    Jenkins, H., Hardy, N., Beckmann, M., Draper, J., Smith, A. R., Taylor, J., . . . Kell, D. B. (2004). A proposed framework for the description of plant metabolomics experiments and their results. NATURE BIOTECHNOLOGY, 22(12), 1601-1606. doi:10.1038/nbt1041

    DOI: 10.1038/nbt1041

    Differentiation of Micromonospora isolates from a coastal sediment in wales on the basis of Fourier transform infrared spectroscopy, 16S rRNA sequence analysis, and the amplified fragment length polymorphism technique (Journal article)

    Zhao, H. J., Kassama, Y., Young, M., Kell, D. B., & Goodacre, R. (2004). Differentiation of Micromonospora isolates from a coastal sediment in wales on the basis of Fourier transform infrared spectroscopy, 16S rRNA sequence analysis, and the amplified fragment length polymorphism technique. APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 70(11), 6619-6627. doi:10.1128/AEM.70.11.6619-6627.2004

    DOI: 10.1128/AEM.70.11.6619-6627.2004

    Oscillations in NF-kappa B signaling control the dynamics of gene expression (Journal article)

    Nelson, D. E., Ihekwaba, A. E. C., Elliott, M., Johnson, J. R., Gibney, C. A., Foreman, B. E., . . . White, M. R. H. (2004). Oscillations in NF-kappa B signaling control the dynamics of gene expression. SCIENCE, 306(5696), 704-708. doi:10.1126/science.1099962

    DOI: 10.1126/science.1099962

    Discrimination of modes of action of antifungal substances by use of metabolic footprinting (Journal article)

    Allen, J., Davey, H. M., Broadhurst, D., Rowland, J. J., Oliver, S. G., & Kell, D. B. (2004). Discrimination of modes of action of antifungal substances by use of metabolic footprinting. APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 70(10), 6157-6165. doi:10.1128/AEM.70.10.6157-6165.2004

    DOI: 10.1128/AEM.70.10.6157-6165.2004

    Selective detection of proteins in mixtures using electrospray ionization mass spectrometry: Influence of instrumental settings and implications for proteomics (Journal article)

    Vaidyanathan, S., Kell, D. B., & Goodacre, R. (2004). Selective detection of proteins in mixtures using electrospray ionization mass spectrometry: Influence of instrumental settings and implications for proteomics. ANALYTICAL CHEMISTRY, 76(17), 5024-5032. doi:10.1021/ac049684+

    DOI: 10.1021/ac049684+

    Selective detection of proteins in mixtures using electrospray ionization mass spectrometry: influence of instrumental settings and implications for proteomics. (Journal article)

    Vaidyanathan, S., Kell, D. B., & Goodacre, R. (2004). Selective detection of proteins in mixtures using electrospray ionization mass spectrometry: influence of instrumental settings and implications for proteomics.. Analytical chemistry, 76(17), 5024-5032. doi:10.1021/ac049684+

    DOI: 10.1021/ac049684+

    Comparative genomic assessment of novel broad-spectrum targets for antibacterial drugs (Journal article)

    White, T. A., & Kell, D. B. (2004). Comparative genomic assessment of novel broad-spectrum targets for antibacterial drugs. COMPARATIVE AND FUNCTIONAL GENOMICS, 5(4), 304-327. doi:10.1002/cfg.411

    DOI: 10.1002/cfg.411

    Metabolomics and systems biology: making sense of the soup (Journal article)

    Kell, D. B. (2004). Metabolomics and systems biology: making sense of the soup. CURRENT OPINION IN MICROBIOLOGY, 7(3), 296-307. doi:10.1016/j.mib.2004.04.012

    DOI: 10.1016/j.mib.2004.04.012

    Sensitivity analysis of parameters controlling oscillatory signalling in the NF-kappaB pathway: the roles of IKK and IkappaBalpha. (Journal article)

    Ihekwaba, A. E. C., Broomhead, D. S., Grimley, R. L., Benson, N., & Kell, D. B. (2004). Sensitivity analysis of parameters controlling oscillatory signalling in the NF-kappaB pathway: the roles of IKK and IkappaBalpha.. Systems biology, 1(1), 93-103. doi:10.1049/sb:20045009

    DOI: 10.1049/sb:20045009

    Metabolomics by numbers: acquiring and understanding global metabolite data (Journal article)

    Goodacre, R., Vaidyanathan, S., Dunn, W. B., Harrigan, G. G., & Kell, D. B. (2004). Metabolomics by numbers: acquiring and understanding global metabolite data. TRENDS IN BIOTECHNOLOGY, 22(5), 245-252. doi:10.1016/j.tibtech.2004.03.007

    DOI: 10.1016/j.tibtech.2004.03.007

    Metabolomics by numbers: acquiring and understanding global metabolite data (Journal article)

    GOODACRE, R. (2004). Metabolomics by numbers: acquiring and understanding global metabolite data. Trends in Biotechnology, 22(5), 245-252. doi:10.1016/s0167-7799(04)00081-2

    DOI: 10.1016/s0167-7799(04)00081-2

    Single-nucleotide polymorphism detection using nanomolar nucleotides and single-molecule fluorescence (Journal article)

    Twist, C. R., Winson, M. K., Rowland, J. J., & Kell, D. B. (2004). Single-nucleotide polymorphism detection using nanomolar nucleotides and single-molecule fluorescence. ANALYTICAL BIOCHEMISTRY, 327(1), 35-44. doi:10.1016/j.ab.2003.12.023

    DOI: 10.1016/j.ab.2003.12.023

    High-throughput metabolic fingerprinting of legume silage fermentations via Fourier transform infrared spectroscopy and chemometrics (Journal article)

    Johnson, H. E., Broadhurst, D., Kell, D. B., Theodorou, M. K., Merry, R. J., & Griffith, G. W. (2004). High-throughput metabolic fingerprinting of legume silage fermentations via Fourier transform infrared spectroscopy and chemometrics. APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 70(3), 1583-1592. doi:10.1128/AEM.70.3.1583-1592.2004

    DOI: 10.1128/AEM.70.3.1583-1592.2004

    Functional genomic hypothesis generation and experimentation by a robot scientist (Journal article)

    King, R. D., Whelan, K. E., Jones, F. M., Reiser, P. G. K., Bryant, C. H., Muggleton, S. H., . . . Oliver, S. G. (2004). Functional genomic hypothesis generation and experimentation by a robot scientist. NATURE, 427(6971), 247-252. doi:10.1038/nature02236

    DOI: 10.1038/nature02236

    Estimation of microbial viability using flow cytometry. (Journal article)

    Davey, H. M., Kell, D. B., Weichart, D. H., & Kaprelyants, A. S. (2004). Estimation of microbial viability using flow cytometry.. Current protocols in cytometry, Chapter 11, Unit-11.3. doi:10.1002/0471142956.cy1103s29

    DOI: 10.1002/0471142956.cy1103s29

    Fast automatic registration of images using the phase of a complex wavelet transform: application to proteome gels (Journal article)

    Woodward, A. M., Rowland, J. J., & Kell, D. B. (2004). Fast automatic registration of images using the phase of a complex wavelet transform: application to proteome gels. ANALYST, 129(6), 542-552. doi:10.1039/b403134b

    DOI: 10.1039/b403134b

    Here is the evidence, now what is the hypothesis? The complementary roles of inductive and hypothesis-driven science in the post-genomic era (Journal article)

    Kell, D. B., & Oliver, S. G. (2004). Here is the evidence, now what is the hypothesis? The complementary roles of inductive and hypothesis-driven science in the post-genomic era. BIOESSAYS, 26(1), 99-105. doi:10.1002/bies.10385

    DOI: 10.1002/bies.10385

    2003

    Explanatory optimization of protein mass spectrometry via genetic search (Journal article)

    Vaidyanathan, S., Broadhurst, D. I., Kell, D. B., & Goodacre, R. (2003). Explanatory optimization of protein mass spectrometry via genetic search. ANALYTICAL CHEMISTRY, 75(23), 6679-6686. doi:10.1021/ac034669a

    DOI: 10.1021/ac034669a

    Functional genomics via metabolic footprinting: monitoring metabolite secretion by Escherichia coli tryptophan metabolism mutants using FT-IR and direct injection electrospray mass spectrometry (Journal article)

    Kaderbhai, N. N., Broadhurst, D. I., Ellis, D. I., Goodacre, R., & Kell, D. B. (2003). Functional genomics via metabolic footprinting: monitoring metabolite secretion by Escherichia coli tryptophan metabolism mutants using FT-IR and direct injection electrospray mass spectrometry. COMPARATIVE AND FUNCTIONAL GENOMICS, 4(4), 376-391. doi:10.1002/cfg.302

    DOI: 10.1002/cfg.302

    Assessing contributions to fitness of individual genes via genome-wide competition analysis. (Conference Paper)

    Delneri, D., Leong, H. S., Hayes, A., Davey, H. M., Kell, D. B., & Oliver, S. G. (2003). Assessing contributions to fitness of individual genes via genome-wide competition analysis.. In YEAST Vol. 20 (pp. S337). Retrieved from http://gateway.webofknowledge.com/

    Metabolic footprinting: a high-throughput, high-information approach to cellular characterisation and functional genomics. (Conference Paper)

    Kell, D. B., Allen, J. K., Davey, H. M., Broadhurst, D. I., Rowland, J. J., & Oliver, S. G. (2003). Metabolic footprinting: a high-throughput, high-information approach to cellular characterisation and functional genomics.. In YEAST Vol. 20 (pp. S335). Retrieved from http://gateway.webofknowledge.com/

    High-throughput classification of yeast mutants for functional genomics using metabolic footprinting (Journal article)

    Allen, J., Davey, H. M., Broadhurst, D., Heald, J. K., Rowland, J. J., Oliver, S. G., & Kell, D. B. (2003). High-throughput classification of yeast mutants for functional genomics using metabolic footprinting. NATURE BIOTECHNOLOGY, 21(6), 692-696. doi:10.1038/nbt823

    DOI: 10.1038/nbt823

    A systematic approach to modeling, capturing, and disseminating proteomics experimental data (Journal article)

    Taylor, C. F., Paton, N. W., Garwood, K. L., Kirby, P. D., Stead, D. A., Yin, Z. K., . . . Oliver, S. G. (2003). A systematic approach to modeling, capturing, and disseminating proteomics experimental data. NATURE BIOTECHNOLOGY, 21(3), 247-254. doi:10.1038/nbt0303-247

    DOI: 10.1038/nbt0303-247

    Adoption of the transiently non-culturable state - a bacterial survival strategy? (Book)

    Mukamolova, G. V., Kaprelyants, A. S., Kell, D. B., & Young, M. (2003). Adoption of the transiently non-culturable state - a bacterial survival strategy? (Vol. 47). doi:10.1016/S0065-2911(03)47002-1

    DOI: 10.1016/S0065-2911(03)47002-1

    Landscape state machines: Tools for evolutionary algorithm performance analyses and landscape/algorithm mapping (Journal article)

    Corne, D., Oates, M., & Kell, D. (2003). Landscape state machines: Tools for evolutionary algorithm performance analyses and landscape/algorithm mapping. APPLICATIONS OF EVOLUTIONARY COMPUTING, 2611, 187-198. Retrieved from http://gateway.webofknowledge.com/

    2002

    Primary and secondary metabolism, and post-translational protein modifications, as portrayed by proteomic analysis of Streptomyces coelicolor (Journal article)

    Hesketh, A. R., Chandra, G., Shaw, A. D., Rowland, J. J., Kell, D. B., Bibb, M. J., & Chater, K. F. (2002). Primary and secondary metabolism, and post-translational protein modifications, as portrayed by proteomic analysis of Streptomyces coelicolor. MOLECULAR MICROBIOLOGY, 46(4), 917-932. doi:10.1046/j.1365-2958.2002.03219.x

    DOI: 10.1046/j.1365-2958.2002.03219.x

    A family of autocrine growth factors in Mycobacterium tuberculosis (Journal article)

    Mukamolova, G. V., Turapov, O. A., Young, D. I., Kaprelyants, A. S., Kell, D. B., & Young, M. (2002). A family of autocrine growth factors in Mycobacterium tuberculosis. MOLECULAR MICROBIOLOGY, 46(3), 623-635. doi:10.1046/j.1365-2958.2002.03184.x

    DOI: 10.1046/j.1365-2958.2002.03184.x

    The rpf gene of Micrococcus luteus encodes an essential secreted growth factor (Journal article)

    Mukamolova, G. V., Turapov, O. A., Kazarian, K., Telkov, M., Kaprelyants, A. S., Kell, D. B., & Young, M. (2002). The rpf gene of Micrococcus luteus encodes an essential secreted growth factor. MOLECULAR MICROBIOLOGY, 46(3), 611-621. doi:10.1046/j.1365-2958.2002.03183.x

    DOI: 10.1046/j.1365-2958.2002.03183.x

    Genotype-phenotype mapping: genes as computer programs (Journal article)

    Kell, D. B. (2002). Genotype-phenotype mapping: genes as computer programs. TRENDS IN GENETICS, 18(11), 555-559. doi:10.1016/S0168-9525(02)02765-8

    DOI: 10.1016/S0168-9525(02)02765-8

    Metabolic profiling using direct infusion electrospray ionisation mass spectrometry for the characterisation of olive oils (Journal article)

    Goodacre, R., Vaidyanathan, S., Bianchi, G., & Kell, D. B. (2002). Metabolic profiling using direct infusion electrospray ionisation mass spectrometry for the characterisation of olive oils. ANALYST, 127(11), 1457-1462. doi:10.1039/b206037j

    DOI: 10.1039/b206037j

    Metabolomics and machine learning: explanatory analysis of complex metabolome data using genetic programming to produce simple, robust rules. (Journal article)

    Kell, D. B. (2002). Metabolomics and machine learning: explanatory analysis of complex metabolome data using genetic programming to produce simple, robust rules.. MOLECULAR BIOLOGY REPORTS, 29(1-2), 237-241. doi:10.1023/A:1020342216314

    DOI: 10.1023/A:1020342216314

    Schemes of flux control in a model of Saccharomyces cerevisiae glycolysis (Journal article)

    Pritchard, L., & Kell, D. B. (2002). Schemes of flux control in a model of Saccharomyces cerevisiae glycolysis. EUROPEAN JOURNAL OF BIOCHEMISTRY, 269(16), 3894-3904. doi:10.1046/j.1432-1033.2002.03055.x

    DOI: 10.1046/j.1432-1033.2002.03055.x

    Rapid, high-throughput microbial characterization by metabolite and protein profiling of whole cells using soft-ionization mass spectrometry. (Conference Paper)

    Vaidyanathan, S., Kell, D. B., & Goodacre, R. (2002). Rapid, high-throughput microbial characterization by metabolite and protein profiling of whole cells using soft-ionization mass spectrometry.. In ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY Vol. 224 (pp. U199). Retrieved from http://gateway.webofknowledge.com/

    Sample preparation in matrix-assisted laser desorption ionization mass spectrometry of whole bacterial cells and the detection of high mass (> 20 kDa) proteins (Journal article)

    Vaidyanathan, S., Winder, C. L., Wade, S. C., Kell, D. B., & Goodacre, R. (2002). Sample preparation in matrix-assisted laser desorption ionization mass spectrometry of whole bacterial cells and the detection of high mass (> 20 kDa) proteins. RAPID COMMUNICATIONS IN MASS SPECTROMETRY, 16(13), 1276-1286. doi:10.1002/rcm.713

    DOI: 10.1002/rcm.713

    The cytochrome p450 complement (CYPome) of Streptomyces coelicolor A3(2) (Journal article)

    Lamb, D. C., Skaug, T., Song, H. L., Jackson, C. J., Podust, L. M., Waterman, M. R., . . . Kelly, S. L. (2002). The cytochrome p450 complement (CYPome) of Streptomyces coelicolor A3(2). JOURNAL OF BIOLOGICAL CHEMISTRY, 277(27), 24000-24005. doi:10.1074/jbc.M111109200

    DOI: 10.1074/jbc.M111109200

    Rapid and quantitative detection of the microbial spoilage of meat by Fourier transform infrared spectroscopy and machine learning (Journal article)

    Ellis, D. I., Broadhurst, D., Kell, D. B., Rowland, J. J., & Goodacre, R. (2002). Rapid and quantitative detection of the microbial spoilage of meat by Fourier transform infrared spectroscopy and machine learning. APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 68(6), 2822-2828. doi:10.1128/AEM.68.6.2822-2828.2002

    DOI: 10.1128/AEM.68.6.2822-2828.2002

    Monitoring of complex industrial bioprocesses for metabolite concentrations using modern spectroscopies and machine learning: Application to gibberellic acid production (Journal article)

    McGovern, A. C., Broadhurst, D., Taylor, J., Kaderbhai, N., Winson, M. K., Small, D. A., . . . Goodacre, R. (2002). Monitoring of complex industrial bioprocesses for metabolite concentrations using modern spectroscopies and machine learning: Application to gibberellic acid production. BIOTECHNOLOGY AND BIOENGINEERING, 78(5), 527-538. Retrieved from http://gateway.webofknowledge.com/

    Monitoring of complex industrial bioprocesses for metabolite concentrations using modern spectroscopies and machine learning: Application to gibberellic acid production (Journal article)

    McGovern, A. C., Broadhurst, D., Taylor, J., Kaderbhai, N., Winson, M. K., Small, D. A., . . . Goodacre, R. (2002). Monitoring of complex industrial bioprocesses for metabolite concentrations using modern spectroscopies and machine learning: Application to gibberellic acid production. Biotechnology and Bioengineering, 78(5), 527-538. doi:10.1002/bit.10226.abs

    DOI: 10.1002/bit.10226.abs

    Flow-injection electrospray ionization mass spectrometry of crude cell extracts for high-throughput bacterial identification (Journal article)

    Vaidyanathan, S., Kell, D. B., & Goodacre, R. (2002). Flow-injection electrospray ionization mass spectrometry of crude cell extracts for high-throughput bacterial identification. JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY, 13(2), 118-128. doi:10.1016/S1044-0305(01)00339-7

    DOI: 10.1016/S1044-0305(01)00339-7

    Formation and resuscitation of 'non-culturable' cells of Rhodococcus rhodochrous and Mycobacterium tuberculosis in prolonged stationary phase (Journal article)

    Shleeva, M. O., Bagramyan, K., Telkov, M. V., Mukamolova, G. V., Young, M., Kell, D. B., & Kaprelyants, A. S. (2002). Formation and resuscitation of 'non-culturable' cells of Rhodococcus rhodochrous and Mycobacterium tuberculosis in prolonged stationary phase. MICROBIOLOGY-SGM, 148, 1581-1591. doi:10.1099/00221287-148-5-1581

    DOI: 10.1099/00221287-148-5-1581

    Differentiation of Phytophthora infestans sporangia from other airborne biological particles by flow Cytometry (Journal article)

    Day, J. P., Kell, D. B., & Griffith, G. W. (2002). Differentiation of Phytophthora infestans sporangia from other airborne biological particles by flow Cytometry. APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 68(1), 37-45. doi:10.1128/AEM.68.1.37-45.2002

    DOI: 10.1128/AEM.68.1.37-45.2002

    Comprehensive Natural Products Chemistry, Volume 4: Amino Acids, Peptides, Porphyrins and Alkaloids (Journal article)

    Kell, D. (2002). Comprehensive Natural Products Chemistry, Volume 4: Amino Acids, Peptides, Porphyrins and Alkaloids. Phytochemistry, 59(2), 231-232. doi:10.1016/s0031-9422(01)00374-0

    DOI: 10.1016/s0031-9422(01)00374-0

    Metabolic Control Analysis and engineering of the yeast sterol biosynthetic pathway (Journal article)

    Groeneveld, P., Rolley, N., Kell, D. B., Kelly, S. L., & Kelly, D. E. (2002). Metabolic Control Analysis and engineering of the yeast sterol biosynthetic pathway. MOLECULAR BIOLOGY REPORTS, 29(1-2), 27-29. doi:10.1023/A:1020342032302

    DOI: 10.1023/A:1020342032302

    On Fitness Distributions and Expected Fitness Gain of Mutation Rates in Parallel Evolutionary Algorithms (Conference Paper)

    Corne, D. W., Oates, M. J., & Kell, D. B. (2002). On Fitness Distributions and Expected Fitness Gain of Mutation Rates in Parallel Evolutionary Algorithms. In Unknown Conference (pp. 132-141). Springer Berlin Heidelberg. doi:10.1007/3-540-45712-7_13

    DOI: 10.1007/3-540-45712-7_13

    Use of flow cytometry in the detection of plant pathogenic spores (Conference Paper)

    Griffith, G. W., Day, J. P., Kell, D. B., & BCPC. (2002). Use of flow cytometry in the detection of plant pathogenic spores. In BCPC CONFERENCE - PESTS & DISEASES 2002, VOLS 1 AND 2 (pp. 417-424). Retrieved from http://gateway.webofknowledge.com/

    2001

    Don't cut the cable (Journal article)

    Kell, D. (2001). Don't cut the cable. New Scientist, 172(2319), 54.

    Discrimination of aerobic endospore-forming bacteria via electrospray-ionization mass spectrometry of whole cell suspensions (Journal article)

    Vaidyanathan, S., Rowland, J. J., Kell, D. B., & Goodacre, R. (2001). Discrimination of aerobic endospore-forming bacteria via electrospray-ionization mass spectrometry of whole cell suspensions. ANALYTICAL CHEMISTRY, 73(17), 4134-4144. doi:10.1021/ac0103524

    DOI: 10.1021/ac0103524

    Characterization of an autostimulatory substance produced by Escherichia coli (Journal article)

    Weichart, D. H., & Kell, D. B. (2001). Characterization of an autostimulatory substance produced by Escherichia coli. MICROBIOLOGY-SGM, 147, 1875-1885. doi:10.1099/00221287-147-7-1875

    DOI: 10.1099/00221287-147-7-1875

    Genomic computing. Explanatory analysis of plant expression profiling data using machine learning (Journal article)

    Kell, D. B., Darby, R. M., & Draper, J. (2001). Genomic computing. Explanatory analysis of plant expression profiling data using machine learning. PLANT PHYSIOLOGY, 126(3), 943-951. doi:10.1104/pp.126.3.943

    DOI: 10.1104/pp.126.3.943

    MEG (Model Extender for Gepasi): a program for the modelling of complex, heterogeneous, cellular systems (Journal article)

    Mendes, P., & Kell, D. B. (2001). MEG (Model Extender for Gepasi): a program for the modelling of complex, heterogeneous, cellular systems. BIOINFORMATICS, 17(3), 288-289. doi:10.1093/bioinformatics/17.3.288

    DOI: 10.1093/bioinformatics/17.3.288

    Macromolecular interactions: tracing the roots (Journal article)

    Clegg, J., Kell, D., Knull, H., Welch, G. R., & Wilson, J. (2001). Macromolecular interactions: tracing the roots. TRENDS IN BIOCHEMICAL SCIENCES, 26(2), 91. doi:10.1016/S0968-0004(00)01739-4

    DOI: 10.1016/S0968-0004(00)01739-4

    A functional genomics strategy that uses metabolome data to reveal the phenotype of silent mutations (Journal article)

    Raamsdonk, L. M., Teusink, B., Broadhurst, D., Zhang, N. S., Hayes, A., Walsh, M. C., . . . Oliver, S. G. (2001). A functional genomics strategy that uses metabolome data to reveal the phenotype of silent mutations. NATURE BIOTECHNOLOGY, 19(1), 45-50. Retrieved from http://gateway.webofknowledge.com/

    ELECTRODE WITH PROTECTIVE COATING (Journal article)

    KELL Douglas Bruce., WOODWARD Andrew Michael., DENYER Stephen., OLLIFF Cedric., & DAVIES Elizabeth. (2001). ELECTRODE WITH PROTECTIVE COATING.

    Chemometric criteria for the characterisation of Italian protected denomination of origin (DOP) olive oils from their metabolic profiles (Journal article)

    Bianchi, G., Giansante, L., Shaw, A., & Kell, D. B. (2001). Chemometric criteria for the characterisation of Italian protected denomination of origin (DOP) olive oils from their metabolic profiles. EUROPEAN JOURNAL OF LIPID SCIENCE AND TECHNOLOGY, 103(3), 141-150. Retrieved from http://gateway.webofknowledge.com/

    Histometrics: Improvement of the dynamic range of fluorescently stained proteins resolved in electrophoretic gels using hyperspectral imaging (Journal article)

    Woodward, A. M., Kaderbhai, N., Kaderbhai, M., Shaw, A., Rowland, J., & Kell, D. B. (2001). Histometrics: Improvement of the dynamic range of fluorescently stained proteins resolved in electrophoretic gels using hyperspectral imaging. PROTEOMICS, 1(11), 1351-1358. Retrieved from http://gateway.webofknowledge.com/

    Spectral analysis via supervised genetic search with application-specific mutations (Conference Paper)

    Taylor, J., Rowland, J. J., Kell, D. B., IEEE., & IEEE. (2001). Spectral analysis via supervised genetic search with application-specific mutations. In PROCEEDINGS OF THE 2001 CONGRESS ON EVOLUTIONARY COMPUTATION, VOLS 1 AND 2 (pp. 481-486). Retrieved from http://gateway.webofknowledge.com/

    2000

    Culturability of Mycobacterium tuberculosis cells isolated from murine macrophages: a bacterial growth factor promotes recovery (Journal article)

    Biketov, S., Mukamolova, G. V., Potapov, V., Gilenkov, E., Vostroknutova, G., Kell, D. B., . . . Kaprelyants, A. S. (2000). Culturability of Mycobacterium tuberculosis cells isolated from murine macrophages: a bacterial growth factor promotes recovery. FEMS IMMUNOLOGY AND MEDICAL MICROBIOLOGY, 29(4), 233-240. doi:10.1111/j.1574-695X.2000.tb01528.x

    DOI: 10.1111/j.1574-695X.2000.tb01528.x

    Culturability of Mycobacterium tuberculosis cells isolated from murine macrophages: a bacterial growth factor promotes recovery (Journal article)

    Biketov, S. (2000). Culturability of Mycobacterium tuberculosis cells isolated from murine macrophages: a bacterial growth factor promotes recovery. FEMS Immunology and Medical Microbiology, 29(4), 233-240. doi:10.1016/s0928-8244(00)00210-8

    DOI: 10.1016/s0928-8244(00)00210-8

    On-line, real-time measurements of cellular biomass using dielectric spectroscopy (Journal article)

    Yardley, Y. E., Kell, D. B., Barrett, J., & Davey, C. L. (2000). On-line, real-time measurements of cellular biomass using dielectric spectroscopy. BIOTECHNOLOGY & GENETIC ENGINEERING REVIEWS, VOL 17, 17, 3-35. doi:10.1080/02648725.2000.10647986

    DOI: 10.1080/02648725.2000.10647986

    Bacterial dormancy and culturability: the role of autocrine growth factors - Commentary (Journal article)

    Kell, D. B., & Young, M. (2000). Bacterial dormancy and culturability: the role of autocrine growth factors - Commentary. CURRENT OPINION IN MICROBIOLOGY, 3(3), 238-243. doi:10.1016/S1369-5274(00)00082-5

    DOI: 10.1016/S1369-5274(00)00082-5

    Screen idols: faster, smaller, cheaper and smarter. (Conference Paper)

    Kell, D. B. (2000). Screen idols: faster, smaller, cheaper and smarter.. In Trends in biotechnology Vol. 18 (pp. 186-187). doi:10.1016/s0167-7799(99)01382-7

    DOI: 10.1016/s0167-7799(99)01382-7

    Efficient improvement of silage additives by using genetic algorithms (Journal article)

    Davies, Z. S., Gilbert, R. J., Merry, R. J., Kell, D. B., Theodorou, M. K., & Griffith, G. W. (2000). Efficient improvement of silage additives by using genetic algorithms. APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 66(4), 1435-1443. doi:10.1128/AEM.66.4.1435-1443.2000

    DOI: 10.1128/AEM.66.4.1435-1443.2000

    Website review - The Kyoto Encyclopedia of Genes and Genomes - KEGG - http://www.genome.ad.jp/kegg (Journal article)

    Wixon, J., & Kell, D. (2000). Website review - The Kyoto Encyclopedia of Genes and Genomes - KEGG - http://www.genome.ad.jp/kegg. YEAST, 17(1), 48-55. doi:3.0.CO;2-H">10.1002/(SICI)1097-0061(200004)17:1<48::AID-YEA2>3.0.CO;2-H

    DOI: 10.1002/(SICI)1097-0061(200004)17:1<48::AID-YEA2>3.0.CO;2-H

    On the optimization of classes for the assignment of unidentified reading frames in functional genomics programmes: the need for machine learning (Journal article)

    Kell, D. B., & King, R. D. (2000). On the optimization of classes for the assignment of unidentified reading frames in functional genomics programmes: the need for machine learning. TRENDS IN BIOTECHNOLOGY, 18(3), 93-98. doi:10.1016/S0167-7799(99)01407-9

    DOI: 10.1016/S0167-7799(99)01407-9

    Correction of the influence of baseline artefacts and electrode polarisation on dielectric spectra (Journal article)

    Yardley, J. E., Todd, R., Nicholson, D. J., Barrett, J., Kell, D. B., & Davey, C. L. (2000). Correction of the influence of baseline artefacts and electrode polarisation on dielectric spectra. BIOELECTROCHEMISTRY, 51(1), 53-65. doi:10.1016/S0302-4598(99)00069-0

    DOI: 10.1016/S0302-4598(99)00069-0

    Non-linear dielectric spectroscopy: antifouling and stabilisation of electrodes by a polymer coating (Journal article)

    Woodward, A. M., Davies, E. A., Denyer, S., Olliff, C., & Kell, D. B. (2000). Non-linear dielectric spectroscopy: antifouling and stabilisation of electrodes by a polymer coating. BIOELECTROCHEMISTRY, 51(1), 13-20. doi:10.1016/S0302-4598(00)00063-5

    DOI: 10.1016/S0302-4598(00)00063-5

    A portable flow cytometer for the detection and identification of microorganisms (Conference Paper)

    Davey, H. M., & Kell, D. B. (2000). A portable flow cytometer for the detection and identification of microorganisms. In RAPID METHODS FOR ANALYSIS OF BIOLOGICAL MATERIALS IN THE ENVIRONMENT Vol. 30 (pp. 159-167). Retrieved from http://gateway.webofknowledge.com/

    Detection of the dipicolinic acid biomarker in Bacillus spores using Curie-point pyrolysis mass spectrometry and fourier transform infrared spectroscopy (Journal article)

    Goodacre, R., Shann, B., Gilbert, R. J., Timmins, E. M., McGovern, A. C., Alsberg, B. K., . . . Logan, N. A. (2000). Detection of the dipicolinic acid biomarker in Bacillus spores using Curie-point pyrolysis mass spectrometry and fourier transform infrared spectroscopy. ANALYTICAL CHEMISTRY, 72(1), 119-127. doi:10.1021/ac990661i

    DOI: 10.1021/ac990661i

    Dormancy in non-sporulating bacteria: Its significance for environmental monitoring (Conference Paper)

    Kaprelyants, A. S., Mukamolova, G. V., Votyakova, T. V., Davey, H. M., & Kell, D. B. (2000). Dormancy in non-sporulating bacteria: Its significance for environmental monitoring. In RAPID METHODS FOR ANALYSIS OF BIOLOGICAL MATERIALS IN THE ENVIRONMENT Vol. 30 (pp. 49-65). Retrieved from http://gateway.webofknowledge.com/

    Intelligent systems for the characterization of microorganisms from hyperspectral data (Conference Paper)

    Goodacre, R., Burton, R., Kaderbhai, N., Timmins, E. M., Woodward, A., Rooney, P. J., & Kell, D. B. (2000). Intelligent systems for the characterization of microorganisms from hyperspectral data. In RAPID METHODS FOR ANALYSIS OF BIOLOGICAL MATERIALS IN THE ENVIRONMENT Vol. 30 (pp. 111-136). Retrieved from http://gateway.webofknowledge.com/

    Rapid analysis of high-dimensional bioprocesses using multivariate spectroscopies and advanced chemometrics. (Journal article)

    Shaw, A. D., Winson, M. K., Woodward, A. M., McGovern, A. C., Davey, H. M., Kaderbhai, N., . . . Rowland, J. J. (2000). Rapid analysis of high-dimensional bioprocesses using multivariate spectroscopies and advanced chemometrics.. Advances in biochemical engineering/biotechnology, 66, 83-113. doi:10.1007/3-540-48773-5_3

    DOI: 10.1007/3-540-48773-5_3

    Snapshots of systems - Metabolic control analysis and biotechnology in the post-genomic era (Conference Paper)

    Kell, D. B., & Mendes, P. (2000). Snapshots of systems - Metabolic control analysis and biotechnology in the post-genomic era. In TECHNOLOGICAL AND MEDICAL IMPLICATIONS OF METABOLIC CONTROL ANALYSIS Vol. 74 (pp. 3-25). Retrieved from http://gateway.webofknowledge.com/

    The use of nonlinear dielectric spectroscopy to monitor the bioelectromagnetic effects of a weak pulsed magnetic field in real time (Journal article)

    Davies, E., Woodward, A., & Kell, D. (2000). The use of nonlinear dielectric spectroscopy to monitor the bioelectromagnetic effects of a weak pulsed magnetic field in real time. BIOELECTROMAGNETICS, 21(1), 25-33. doi:3.3.CO;2-0">10.1002/(SICI)1521-186X(200001)21:1<25::AID-BEM5>3.3.CO;2-0

    DOI: 10.1002/(SICI)1521-186X(200001)21:1<25::AID-BEM5>3.3.CO;2-0

    1999

    Intelligent systems for the characterisation and quantification of microbial systems from advanced analytical techniques (Conference Paper)

    Goodacre, R., McGovern, A. C., Timmins, E. M., Winson, M. K., Kaderbhai, N., Broadhurst, D., . . . Kell, D. B. (1999). Intelligent systems for the characterisation and quantification of microbial systems from advanced analytical techniques. In ENVIRONMENTAL MONITORING AND REMEDIATION TECHNOLOGIES II Vol. 3853 (pp. 174-184). doi:10.1117/12.372851

    DOI: 10.1117/12.372851

    Use of C-13 nuclear magnetic resonance distortionless enhancement by polarization transfer pulse sequence and multivariate analysis to discriminate olive oil cultivars (Journal article)

    Vlahov, G., Shaw, A. D., & Kell, D. B. (1999). Use of C-13 nuclear magnetic resonance distortionless enhancement by polarization transfer pulse sequence and multivariate analysis to discriminate olive oil cultivars. JOURNAL OF THE AMERICAN OIL CHEMISTS SOCIETY, 76(10), 1223-1231. doi:10.1007/s11746-999-0098-z

    DOI: 10.1007/s11746-999-0098-z

    Screensavers: trends in high-throughput analysis. (Journal article)

    Kell, D. (1999). Screensavers: trends in high-throughput analysis.. Trends in biotechnology, 17(3), 89-91. doi:10.1016/s0167-7799(98)01273-6

    DOI: 10.1016/s0167-7799(98)01273-6

    Rapid analysis of the expression of heterologous proteins in Escherichia coli using pyrolysis mass spectrometry and Fourier transform infrared spectroscopy with chemometrics: application to alpha 2-interferon production (Journal article)

    McGovern, A. C., Ernill, R., Kara, B. V., Kell, D. B., & Goodacre, R. (1999). Rapid analysis of the expression of heterologous proteins in Escherichia coli using pyrolysis mass spectrometry and Fourier transform infrared spectroscopy with chemometrics: application to alpha 2-interferon production. JOURNAL OF BIOTECHNOLOGY, 72(3), 157-167. doi:10.1016/S0168-1656(99)00128-5

    DOI: 10.1016/S0168-1656(99)00128-5

    Characterisation of intact microorganisms using electrospray ionisation mass spectrometry (Journal article)

    Goodacre, R., Heald, J. K., & Kell, D. B. (1999). Characterisation of intact microorganisms using electrospray ionisation mass spectrometry. FEMS MICROBIOLOGY LETTERS, 176(1), 17-24. doi:10.1111/j.1574-6968.1999.tb13636.x

    DOI: 10.1111/j.1574-6968.1999.tb13636.x

    Characterisation of intact microorganisms using electrospray ionisation mass spectrometry (Journal article)

    Goodacre, R. (1999). Characterisation of intact microorganisms using electrospray ionisation mass spectrometry. FEMS Microbiology Letters, 176(1), 17-24. doi:10.1016/s0378-1097(99)00212-8

    DOI: 10.1016/s0378-1097(99)00212-8

    Stimulation of the multiplication of Micrococcus luteus by an autocrine growth factor (Journal article)

    Mukamolova, G. V., Kormer, S. S., Kell, D. B., & Kaprelyants, A. S. (1999). Stimulation of the multiplication of Micrococcus luteus by an autocrine growth factor. ARCHIVES OF MICROBIOLOGY, 172(1), 9-14. doi:10.1007/s002030050733

    DOI: 10.1007/s002030050733

    Genetic programming as an analytical tool for non-linear dielectric spectroscopy (Journal article)

    Woodward, A. M., Gilbert, R. J., & Kell, D. B. (1999). Genetic programming as an analytical tool for non-linear dielectric spectroscopy. BIOELECTROCHEMISTRY AND BIOENERGETICS, 48(2), 389-396. doi:10.1016/S0302-4598(99)00022-7

    DOI: 10.1016/S0302-4598(99)00022-7

    Revolutionary ideas come round again (Journal article)

    Kell, D. B. (1999). Revolutionary ideas come round again. NATURE, 397(6721), 644. doi:10.1038/17672

    DOI: 10.1038/17672

    A weak pulsed magnetic field affects adenine nucleotide oscillations, and related parameters in aggregating Dictyostelium discoideum amoebae (Journal article)

    Davies, E., Olliff, C., Wright, I., Woodward, A., & Kell, D. (1999). A weak pulsed magnetic field affects adenine nucleotide oscillations, and related parameters in aggregating Dictyostelium discoideum amoebae. BIOELECTROCHEMISTRY AND BIOENERGETICS, 48(1), 149-162. doi:10.1016/S0302-4598(98)00237-2

    DOI: 10.1016/S0302-4598(98)00237-2

    Variable selection and multivariate methods for the identification of microorganisms by flow cytometry (Journal article)

    Davey, H. M., Jones, A., Shaw, A. D., & Kell, D. B. (1999). Variable selection and multivariate methods for the identification of microorganisms by flow cytometry. CYTOMETRY, 35(2), 162-168. doi:3.0.CO;2-U">10.1002/(SICI)1097-0320(19990201)35:2<162::AID-CYTO8>3.0.CO;2-U

    DOI: 10.1002/(SICI)1097-0320(19990201)35:2<162::AID-CYTO8>3.0.CO;2-U

    Intercellular signalling and the multiplication of prokaryotes: Bacterial cytokines (Conference Paper)

    Kaprelyants, A. S., Mukamolova, G. V., Kormer, S. S., Weichart, D. H., Young, M., & Kell, D. B. (1999). Intercellular signalling and the multiplication of prokaryotes: Bacterial cytokines. In MICROBIAL SIGNALLING AND COMMUNICATION Vol. 57 (pp. 33-69). Retrieved from http://gateway.webofknowledge.com/

    Noninvasive, on-line monitoring of the biotransformation by yeast of glucose to ethanol using dispersive Raman spectroscopy and chemometrics (Journal article)

    Shaw, A. D., Kaderbhai, N., Jones, A., Woodward, A. M., Goodacre, R., Rowland, J. J., & Kell, D. B. (1999). Noninvasive, on-line monitoring of the biotransformation by yeast of glucose to ethanol using dispersive Raman spectroscopy and chemometrics. APPLIED SPECTROSCOPY, 53(11), 1419-1428. doi:10.1366/0003702991945777

    DOI: 10.1366/0003702991945777

    Use of 13C nuclear magnetic resonance distortionless enhancement by polarization transfer pulse sequence and multivariate analysis to discriminate olive oil cultivars (Journal article)

    Vlahov, G., Shaw, A. D., & Kell, D. B. (1999). Use of 13C nuclear magnetic resonance distortionless enhancement by polarization transfer pulse sequence and multivariate analysis to discriminate olive oil cultivars. JAOCS, Journal of the American Oil Chemists' Society, 76(10), 1223-1231. doi:10.1007/s11746-999-0098-z

    DOI: 10.1007/s11746-999-0098-z

    1998

    A DRASTIC (Diffuse Reflectance Absorbance Spectroscopy Taking In Chemometrics) approach for the rapid analysis of microbial fermentation products: Quantification of aristeromycin and neplanocin A in Streptomyces citricolor broths. (Conference Paper)

    Winson, M. K., Todd, M., Rudd, B. A. M., Jones, A., Alsberg, B. K., Woodward, A. M., . . . Kell, D. B. (1998). A DRASTIC (Diffuse Reflectance Absorbance Spectroscopy Taking In Chemometrics) approach for the rapid analysis of microbial fermentation products: Quantification of aristeromycin and neplanocin A in Streptomyces citricolor broths.. In NEW FRONTIERS IN SCREENING FOR MICROBIAL BIOCATALYSTS Vol. 53 (pp. 185-191). Retrieved from http://gateway.webofknowledge.com/

    DRASTIC (Diffuse Reflectance Absorbance Spectroscopy Taking In Chemometrics). A novel, rapid, hyperspectral, FT-IR-based approach to screening for biocatalytic activity and metabolite overproduction (Journal article)

    Kell, D. B., Winson, M. K., Goodacre, R., Woodward, A. M., Alsberg, B. K., Jones, A., . . . Rowland, J. J. (1998). DRASTIC (Diffuse Reflectance Absorbance Spectroscopy Taking In Chemometrics). A novel, rapid, hyperspectral, FT-IR-based approach to screening for biocatalytic activity and metabolite overproduction. NEW FRONTIERS IN SCREENING FOR MICROBIAL BIOCATALYSTS, 53, 61-75. Retrieved from http://gateway.webofknowledge.com/

    From code to mode for orphan genes (Conference Paper)

    Kell, D. (1998). From code to mode for orphan genes. In Trends in Biotechnology Vol. 16 (pp. 491-493). Elsevier BV. doi:10.1016/s0167-7799(98)01254-2

    DOI: 10.1016/s0167-7799(98)01254-2

    Research on the heterogeneity of a Micrococcus luteus culture during an extended stationary phase: Subpopulation separation and characterization (Journal article)

    Votyakova, T. V., Mukamolova, G. V., Shtein-Margolina, V. A., Popov, V. I., Davey, H. M., Kell, D. B., & Kaprel'yants, A. S. (1998). Research on the heterogeneity of a Micrococcus luteus culture during an extended stationary phase: Subpopulation separation and characterization. MICROBIOLOGY, 67(1), 71-77. Retrieved from http://gateway.webofknowledge.com/

    Non-linear optimization of biochemical pathways: applications to metabolic engineering and parameter estimation (Journal article)

    Mendes, P., & Kell, D. B. (1998). Non-linear optimization of biochemical pathways: applications to metabolic engineering and parameter estimation. BIOINFORMATICS, 14(10), 869-883. doi:10.1093/bioinformatics/14.10.869

    DOI: 10.1093/bioinformatics/14.10.869

    On resuscitation from the dormant state of Micrococcus luteus (Journal article)

    Mukamolova, G. V., Yanopolskaya, N. D., Kell, D. B., & Kaprelyants, A. S. (1998). On resuscitation from the dormant state of Micrococcus luteus. ANTONIE VAN LEEUWENHOEK INTERNATIONAL JOURNAL OF GENERAL AND MOLECULAR MICROBIOLOGY, 73(3), 237-243. doi:10.1023/A:1000881918216

    DOI: 10.1023/A:1000881918216

    Variable selection in discriminant partial least-squares analysis (Journal article)

    Alsberg, B. K., Kell, D. B., & Goodacre, R. (1998). Variable selection in discriminant partial least-squares analysis. ANALYTICAL CHEMISTRY, 70(19), 4126-4133. doi:10.1021/ac980506o

    DOI: 10.1021/ac980506o

    Systematic functional analysis of the yeast genome (Journal article)

    Oliver, S. G., Winson, M. K., Kell, D. B., & Baganz, F. (1998). Systematic functional analysis of the yeast genome. TRENDS IN BIOTECHNOLOGY, 16(9), 373-378. doi:10.1016/S0167-7799(98)01214-1

    DOI: 10.1016/S0167-7799(98)01214-1

    Viability and activity in readily culturable bacteria: a review and discussion of the practical issues (Journal article)

    Kell, D. B., Kaprelyants, A. S., Weichart, D. H., Harwood, C. R., & Barer, M. R. (1998). Viability and activity in readily culturable bacteria: a review and discussion of the practical issues. ANTONIE VAN LEEUWENHOEK INTERNATIONAL JOURNAL OF GENERAL AND MOLECULAR MICROBIOLOGY, 73(2), 169-187. doi:10.1023/A:1000664013047

    DOI: 10.1023/A:1000664013047

    Microbial stress and culturability: conceptual and operational domains (Journal article)

    Barer, M. R., Kaprelyants, A. S., Weichart, D. H., Harwood, C. R., & Kell, D. B. (1998). Microbial stress and culturability: conceptual and operational domains. MICROBIOLOGY-SGM, 144, 2009-2010. doi:10.1099/00221287-144-8-2009

    DOI: 10.1099/00221287-144-8-2009

    A bacterial cytokine (Journal article)

    Mukamolova, G. V., Kaprelyants, A. S., Young, D. I., Young, M., & Kell, D. B. (1998). A bacterial cytokine. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 95(15), 8916-8921. doi:10.1073/pnas.95.15.8916

    DOI: 10.1073/pnas.95.15.8916

    Quantification of microbial productivity via multi-angle light scattering and supervised learning (Journal article)

    Jones, A., Young, D., Taylor, J., Kell, D. B., & Rowland, J. J. (1998). Quantification of microbial productivity via multi-angle light scattering and supervised learning. BIOTECHNOLOGY AND BIOENGINEERING, 59(2), 131-143. doi:3.0.CO;2-I">10.1002/(SICI)1097-0290(19980720)59:2<131::AID-BIT1>3.0.CO;2-I

    DOI: 10.1002/(SICI)1097-0290(19980720)59:2<131::AID-BIT1>3.0.CO;2-I

    Variable selection in wavelet regression models (Journal article)

    Alsberg, B. K., Woodward, A. M., Winson, M. K., Rowland, J. J., & Kell, D. B. (1998). Variable selection in wavelet regression models. ANALYTICA CHIMICA ACTA, 368(1-2), 29-44. doi:10.1016/S0003-2670(98)00194-9

    DOI: 10.1016/S0003-2670(98)00194-9

    BACTERIAL PHEROMONES AND USES THEREFOR (Journal article)

    KAPRELYANTS Arseny S.., KELL Douglas B.., MUKAMOLOVA Galina V.., YOUNG Danielle I.., & YOUNG Michael. (1998). BACTERIAL PHEROMONES AND USES THEREFOR.

    BACTERIAL PHEROMONES AND USES THEREFOR (Journal article)

    MUKAMOLOVA GALINA V., KAPRELYANTS ARSENY S., YOUNG DANIELLE I., KELL DOUGLAS B., & YOUNG MICHAEL. (1998). BACTERIAL PHEROMONES AND USES THEREFOR.

    (Journal article)

    MUKAMOLOVA GALINA V., KAPRELYANTS ARSENY S., YOUNG DANIELLE., KELL DOUGLAS., & YOUNG MICHAEL. (1998). .

    (Journal article)

    YOUNG DANIELLE I., YOUNG MICHAEL., MUKAMOLOVA GALINA V., KAPRELYANTS ARSENY S., & KELL DOUGLAS B. (1998). .

    Rapid identification of urinary tract infection bacteria using hyperspectral whole-organism fingerprinting and artificial neural networks (Journal article)

    Goodacre, R., Timmins, E. M., Burton, R., Kaderbhai, N., Woodward, A. M., Kell, D. B., & Rooney, P. J. (1998). Rapid identification of urinary tract infection bacteria using hyperspectral whole-organism fingerprinting and artificial neural networks. MICROBIOLOGY-SGM, 144, 1157-1170. doi:10.1099/00221287-144-5-1157

    DOI: 10.1099/00221287-144-5-1157

    The effect of heteroscedastic noise on the chemometric modelling of frequency domain data (Journal article)

    Woodward, A. M., Alsberg, B. K., & Kell, D. B. (1998). The effect of heteroscedastic noise on the chemometric modelling of frequency domain data. CHEMOMETRICS AND INTELLIGENT LABORATORY SYSTEMS, 40(1), 101-107. doi:10.1016/S0169-7439(97)00078-6

    DOI: 10.1016/S0169-7439(97)00078-6

    Rapid analysis of microbial systems using vibrational spectroscopy and supervised learning methods: application to the discrimination between methicillin-resistant and methicillin-susceptible Staphylococcus aureus. (Conference Paper)

    Goodacre, R., Rooney, P. J., & Kell, D. B. (1998). Rapid analysis of microbial systems using vibrational spectroscopy and supervised learning methods: application to the discrimination between methicillin-resistant and methicillin-susceptible Staphylococcus aureus.. In INFRARED SPECTROSCOPY: NEW TOOL IN MEDICINE, PROCEEDINGS OF Vol. 3257 (pp. 220-229). doi:10.1117/12.306087

    DOI: 10.1117/12.306087

    The deconvolution of pyrolysis mass spectra using genetic programming: application to the identification of some Eubacterium species (Journal article)

    Taylor, J., Goodacre, R., Wade, W. G., Rowland, J. J., & Kell, D. B. (1998). The deconvolution of pyrolysis mass spectra using genetic programming: application to the identification of some Eubacterium species. FEMS MICROBIOLOGY LETTERS, 160(2), 237-246. doi:10.1016/S0378-1097(98)00038-X

    DOI: 10.1016/S0378-1097(98)00038-X

    The deconvolution of pyrolysis mass spectra using genetic programming: application to the identification of some Eubacterium species (Journal article)

    Taylor, J. (1998). The deconvolution of pyrolysis mass spectra using genetic programming: application to the identification of some Eubacterium species. FEMS Microbiology Letters, 160(2), 237-246. doi:10.1016/s0378-1097(98)00038-x

    DOI: 10.1016/s0378-1097(98)00038-x

    Dielectric estimation of microbial biomass using the Aber instruments biomass monitor (Journal article)

    Kell, D., & Todd, R. W. (1998). Dielectric estimation of microbial biomass using the Aber instruments biomass monitor. TRENDS IN BIOTECHNOLOGY, 16(4), 149-150. doi:10.1016/S0167-7799(98)01175-5

    DOI: 10.1016/S0167-7799(98)01175-5

    Discrimination between methicillin-resistant and methicillin-susceptible Staphylococcus aureus using pyrolysis mass spectrometry and artificial neural networks (Journal article)

    Goodacre, R., Rooney, P. J., & Kell, D. B. (1998). Discrimination between methicillin-resistant and methicillin-susceptible Staphylococcus aureus using pyrolysis mass spectrometry and artificial neural networks. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 41(1), 27-34. doi:10.1093/jac/41.1.27

    DOI: 10.1093/jac/41.1.27

    Rheological phenomena occurring during the shearing flow of mayonnaise (Journal article)

    Goshawk, J. A., Binding, D. M., Kell, D. B., & Goodacre, R. (1998). Rheological phenomena occurring during the shearing flow of mayonnaise. JOURNAL OF RHEOLOGY, 42(6), 1537-1553. doi:10.1122/1.550967

    DOI: 10.1122/1.550967

    The influence of electrode polarisation on dielectric spectra, with special reference to capacitive biomass measurements - I. Quantifying the effects on electrode polarisation of factors likely to occur during fermentations (Journal article)

    Davey, C. L., & Kell, D. B. (1998). The influence of electrode polarisation on dielectric spectra, with special reference to capacitive biomass measurements - I. Quantifying the effects on electrode polarisation of factors likely to occur during fermentations. BIOELECTROCHEMISTRY AND BIOENERGETICS, 46(1), 91-103. doi:10.1016/S0302-4598(98)00131-7

    DOI: 10.1016/S0302-4598(98)00131-7

    The influence of electrode polarisation on dielectric spectra, with special reference to capacitive biomass measurements: (II) Reduction in the contribution of electrode polarisation to dielectric spectra using a two-frequency method (Journal article)

    Davey, C. L., & Kell, D. B. (1998). The influence of electrode polarisation on dielectric spectra, with special reference to capacitive biomass measurements: (II) Reduction in the contribution of electrode polarisation to dielectric spectra using a two-frequency method. BIOELECTROCHEMISTRY AND BIOENERGETICS, 46(1), 105-114. doi:10.1016/S0302-4598(98)00132-9

    DOI: 10.1016/S0302-4598(98)00132-9

    1997

    Genetic programming: A novel method for the quantitative analysis of pyrolysis mass spectral data (Journal article)

    Gilbert, R. J., Goodacre, R., Woodward, A. M., & Kell, D. B. (1997). Genetic programming: A novel method for the quantitative analysis of pyrolysis mass spectral data. ANALYTICAL CHEMISTRY, 69(21), 4381-4389. doi:10.1021/ac970460j

    DOI: 10.1021/ac970460j

    Capacitance measurement of a dielectric medium (Journal article)

    DAVEY CHRISTOPHER LYNDON., & KELL DOUGLAS BRUCE. (1997). Capacitance measurement of a dielectric medium.

    Cheques and balances (Journal article)

    Kell, D. B. (1997). Cheques and balances. NATURE, 389(6648), 224. doi:10.1038/38374

    DOI: 10.1038/38374

    Classification of pyrolysis mass spectra by fuzzy multivariate rule induction-comparison with regression, K-nearest neighbour, neural and decision-tree methods (Conference Paper)

    Alsberg, B. K., Goodacre, R., Rowland, J. J., & Kell, D. B. (1997). Classification of pyrolysis mass spectra by fuzzy multivariate rule induction-comparison with regression, K-nearest neighbour, neural and decision-tree methods. In ANALYTICA CHIMICA ACTA Vol. 348 (pp. 389-407). doi:10.1016/S0003-2670(97)00064-0

    DOI: 10.1016/S0003-2670(97)00064-0

    Diffuse reflectance absorbance spectroscopy taking in chemometrics (DRASTIC). A hyperspectral FT-IR-based approach to rapid screening for metabolite overproduction (Conference Paper)

    Winson, M. K., Goodacre, R., Timmins, E. M., Jones, A., Alsberg, B. K., Woodward, A. M., . . . Kell, D. B. (1997). Diffuse reflectance absorbance spectroscopy taking in chemometrics (DRASTIC). A hyperspectral FT-IR-based approach to rapid screening for metabolite overproduction. In ANALYTICA CHIMICA ACTA Vol. 348 (pp. 273-282). doi:10.1016/S0003-2670(97)00237-7

    DOI: 10.1016/S0003-2670(97)00237-7

    Discrimination of the variety and region of origin of extra virgin olive oils using C-13 NMR and multivariate calibration with variable reduction (Conference Paper)

    Shaw, A. D., diCamillo, A., Vlahov, G., Jones, A., Bianchi, G., Rowland, J., & Kell, D. B. (1997). Discrimination of the variety and region of origin of extra virgin olive oils using C-13 NMR and multivariate calibration with variable reduction. In ANALYTICA CHIMICA ACTA Vol. 348 (pp. 357-374). doi:10.1016/S0003-2670(97)00037-8

    DOI: 10.1016/S0003-2670(97)00037-8

    Genetic algorithms as a method for variable selection in multiple linear regression and partial least squares regression, with applications to pyrolysis mass spectrometry (Conference Paper)

    Broadhurst, D., Goodacre, R., Jones, A., Rowland, J. J., & Kell, D. B. (1997). Genetic algorithms as a method for variable selection in multiple linear regression and partial least squares regression, with applications to pyrolysis mass spectrometry. In ANALYTICA CHIMICA ACTA Vol. 348 (pp. 71-86). doi:10.1016/S0003-2670(97)00065-2

    DOI: 10.1016/S0003-2670(97)00065-2

    On mass spectrometer instrument standardization and interlaboratory calibration transfer using neural networks (Conference Paper)

    Goodacre, R., Timmins, E. M., Jones, A., Kell, D. B., Maddock, J., Heginbothom, M. L., & Magee, J. T. (1997). On mass spectrometer instrument standardization and interlaboratory calibration transfer using neural networks. In ANALYTICA CHIMICA ACTA Vol. 348 (pp. 511-532). doi:10.1016/S0003-2670(97)00062-7

    DOI: 10.1016/S0003-2670(97)00062-7

    Enantioselectivity of sulcatone reduction by some anaerobic bacteria (Journal article)

    Tidswell, E. C., Salter, G. J., Kell, D. B., & Morris, J. G. (1997). Enantioselectivity of sulcatone reduction by some anaerobic bacteria. ENZYME AND MICROBIAL TECHNOLOGY, 21(2), 143-147. doi:10.1016/S0141-0229(96)00264-5

    DOI: 10.1016/S0141-0229(96)00264-5

    Fluorescent brighteners: Novel stains for the flow cytometric analysis of microorganisms (Journal article)

    Davey, H. M., & Kell, D. B. (1997). Fluorescent brighteners: Novel stains for the flow cytometric analysis of microorganisms. CYTOMETRY, 28(4), 311-315. doi:3.0.CO;2-E">10.1002/(SICI)1097-0320(19970801)28:4<311::AID-CYTO6>3.0.CO;2-E

    DOI: 10.1002/(SICI)1097-0320(19970801)28:4<311::AID-CYTO6>3.0.CO;2-E

    You've got it, flaunt it - Rapid screening for microbial biocatalysts (Conference Paper)

    Winson, M. K., & Kell, D. B. (1997). You've got it, flaunt it - Rapid screening for microbial biocatalysts. In TRENDS IN BIOTECHNOLOGY Vol. 15 (pp. 120-122). doi:10.1016/S0167-7799(97)01009-3

    DOI: 10.1016/S0167-7799(97)01009-3

    An instrument for the acquisition and analysis of the nonlinear dielectric spectra of biological samples (Journal article)

    Jones, A., Rowland, J. J., Woodward, A. M., & Kell, D. B. (1997). An instrument for the acquisition and analysis of the nonlinear dielectric spectra of biological samples. TRANSACTIONS OF THE INSTITUTE OF MEASUREMENT AND CONTROL, 19(5), 223-230. doi:10.1177/014233129701900502

    DOI: 10.1177/014233129701900502

    An introduction to wavelet transforms for chemometricians: A time-frequency approach (Journal article)

    Alsberg, B. K., Woodward, A. M., & Kell, D. B. (1997). An introduction to wavelet transforms for chemometricians: A time-frequency approach. CHEMOMETRICS AND INTELLIGENT LABORATORY SYSTEMS, 37(2), 215-239. doi:10.1016/S0169-7439(97)00029-4

    DOI: 10.1016/S0169-7439(97)00029-4

    Determination of the geographical origin of Italian extra virgin olive oil using pyrolysis mass spectrometry and artificial neural networks (Journal article)

    Salter, G. J., Lazzari, M., Giansante, L., Goodacre, R., Jones, A., Surricchio, G., . . . Bianchi, G. (1997). Determination of the geographical origin of Italian extra virgin olive oil using pyrolysis mass spectrometry and artificial neural networks. JOURNAL OF ANALYTICAL AND APPLIED PYROLYSIS, 40-1, 159-170. doi:10.1016/S0165-2370(96)00975-8

    DOI: 10.1016/S0165-2370(96)00975-8

    Improving the interpretation of multivariate and rule induction models by using a peak parameter representation (Journal article)

    Alsberg, B. K., Winson, M. K., & Kell, D. B. (1997). Improving the interpretation of multivariate and rule induction models by using a peak parameter representation. CHEMOMETRICS AND INTELLIGENT LABORATORY SYSTEMS, 36(2), 95-109. doi:10.1016/S0169-7439(97)00024-5

    DOI: 10.1016/S0169-7439(97)00024-5

    Making cells work - Metabolic engineering for everyone (Conference Paper)

    Mendes, P., & Kell, D. (1997). Making cells work - Metabolic engineering for everyone. In TRENDS IN BIOTECHNOLOGY Vol. 15 (pp. 6-7). doi:10.1016/S0167-7799(96)30030-9

    DOI: 10.1016/S0167-7799(96)30030-9

    Quantitative analysis of the adulteration of orange juice with sucrose using pyrolysis mass spectrometry and chemometrics (Conference Paper)

    Goodacre, R., Hammond, D., & Kell, D. B. (1997). Quantitative analysis of the adulteration of orange juice with sucrose using pyrolysis mass spectrometry and chemometrics. In JOURNAL OF ANALYTICAL AND APPLIED PYROLYSIS Vol. 40-1 (pp. 135-158). doi:10.1016/S0165-2370(96)00973-4

    DOI: 10.1016/S0165-2370(96)00973-4

    Real-time monitoring of the biomass content of animal cell cultures using dielectric spectroscopy. (Conference Paper)

    Davey, C. L., Guan, Y., Kemp, R. B., & Kell, D. B. (1997). Real-time monitoring of the biomass content of animal cell cultures using dielectric spectroscopy.. In ANIMAL CELL TECHNOLOGY: BASIC & APPLIED ASPECTS, VOL 8 (pp. 61-65). Retrieved from http://gateway.webofknowledge.com/

    Target practice - novel approaches to antimicrobial chemotherapy (Journal article)

    Kell, D. B. (1997). Target practice - novel approaches to antimicrobial chemotherapy. TRENDS IN BIOTECHNOLOGY, 15(9), 334-336. doi:10.1016/S0167-7799(97)01078-0

    DOI: 10.1016/S0167-7799(97)01078-0

    Wavelet denoising of infrared spectra (Journal article)

    Alsberg, B. K., Woodward, A. M., Winson, M. K., Rowland, J., & Kell, D. B. (1997). Wavelet denoising of infrared spectra. ANALYST, 122(7), 645-652. doi:10.1039/a608255f

    DOI: 10.1039/a608255f

    1996

    A matter of fact (Journal article)

    Kell, D. (1996). A matter of fact. New Scientist, 152(2050), 56.

    What biotechnologists knew all along ...? (Journal article)

    Westerhoff, H. V., & Kell, D. B. (1996). What biotechnologists knew all along ...?. JOURNAL OF THEORETICAL BIOLOGY, 182(3), 411-420. doi:10.1006/jtbi.1996.0181

    DOI: 10.1006/jtbi.1996.0181

    Rapid identification of Streptococcus and Enterococcus species using diffuse reflectance-absorbance Fourier transform infrared spectroscopy and artificial neural networks (Journal article)

    Goodacre, R., Timmins, E. M., Rooney, P. J., Rowland, J. J., & Kell, D. B. (1996). Rapid identification of Streptococcus and Enterococcus species using diffuse reflectance-absorbance Fourier transform infrared spectroscopy and artificial neural networks. FEMS MICROBIOLOGY LETTERS, 140(2-3), 233-239. doi:10.1016/0378-1097(96)00186-3

    DOI: 10.1016/0378-1097(96)00186-3

    Rapid identification of Streptococcus and Enterococcus species using diffuse reflectance-absorbance Fourier transform infrared spectroscopy and artificial neural networks (Journal article)

    Goodacre, R. (1996). Rapid identification of Streptococcus and Enterococcus species using diffuse reflectance-absorbance Fourier transform infrared spectroscopy and artificial neural networks. FEMS Microbiology Letters, 140(2-3), 233-239. doi:10.1016/0378-1097(96)00186-3

    DOI: 10.1016/0378-1097(96)00186-3

    Rapid identification of Streptococcus and Enterococcus species using diffuse reflectance-absorbance Fourier transform infrared spectroscopy and artificial neural networks. (Journal article)

    Goodacre, R., Timmins, E. M., Rooney, P. J., Rowland, J. J., & Kell, D. B. (1996). Rapid identification of Streptococcus and Enterococcus species using diffuse reflectance-absorbance Fourier transform infrared spectroscopy and artificial neural networks.. FEMS microbiology letters, 140(2-3), 233-239. doi:10.1016/0378-1097(96)00186-3

    DOI: 10.1016/0378-1097(96)00186-3

    Membrane tension (Journal article)

    Kell, D. B. (1996). Membrane tension. TRENDS IN CELL BIOLOGY, 6(5), 171. doi:10.1016/0962-8924(96)80980-9

    DOI: 10.1016/0962-8924(96)80980-9

    Why and when channelling can decrease pool size at constant net flux in a simple dynamic channel (Journal article)

    Mendes, P., Kell, D. B., & Westerhoff, H. V. (1996). Why and when channelling can decrease pool size at constant net flux in a simple dynamic channel. BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS, 1289(2), 175-186. doi:10.1016/0304-4165(95)00152-2

    DOI: 10.1016/0304-4165(95)00152-2

    BIOMASS MEASUREMENT APPARATUS AND METHOD (Journal article)

    KELL Douglas Bruce., NICHOLSON David John., & DAVEY Christopher Lyndon. (1996). BIOMASS MEASUREMENT APPARATUS AND METHOD.

    Pyrolysis mass spectrometry and its applications in biotechnology (Journal article)

    Goodacre, R., & Kell, D. B. (1996). Pyrolysis mass spectrometry and its applications in biotechnology. CURRENT OPINION IN BIOTECHNOLOGY, 7(1), 20-28. doi:10.1016/S0958-1669(96)80090-5

    DOI: 10.1016/S0958-1669(96)80090-5

    Correction of mass spectral drift using artificial neural networks (Journal article)

    Goodacre, R., & Kell, D. B. (1996). Correction of mass spectral drift using artificial neural networks. ANALYTICAL CHEMISTRY, 68(2), 271-280. doi:10.1021/ac950671t

    DOI: 10.1021/ac950671t

    Deconvolution of the dielectric spectra of microbial cell suspensions using multivariate calibration and artificial neural networks (Journal article)

    Nicholson, D. J., Kell, D. B., & Davey, C. L. (1996). Deconvolution of the dielectric spectra of microbial cell suspensions using multivariate calibration and artificial neural networks. BIOELECTROCHEMISTRY AND BIOENERGETICS, 39(2), 185-193. doi:10.1016/0302-4598(95)01890-5

    DOI: 10.1016/0302-4598(95)01890-5

    Do bacteria need to communicate with each other for growth? (Journal article)

    Kaprelyants, A. S., & Kell, D. B. (1996). Do bacteria need to communicate with each other for growth?. TRENDS IN MICROBIOLOGY, 4(6), 237-242. doi:10.1016/0966-842X(96)10035-4

    DOI: 10.1016/0966-842X(96)10035-4

    Flow cytometry and cell sorting of heterogeneous microbial populations: The importance of single-cell analyses (Journal article)

    Davey, H. M., & Kell, D. B. (1996). Flow cytometry and cell sorting of heterogeneous microbial populations: The importance of single-cell analyses. MICROBIOLOGICAL REVIEWS, 60(4), 641-+. doi:10.1128/MMBR.60.4.641-696.1996

    DOI: 10.1128/MMBR.60.4.641-696.1996

    Going places: Forced and natural molecular evolution (Conference Paper)

    Winson, M. K., & Kell, D. B. (1996). Going places: Forced and natural molecular evolution. In TRENDS IN BIOTECHNOLOGY Vol. 14 (pp. 323-325). doi:10.1016/0167-7799(96)30013-9

    DOI: 10.1016/0167-7799(96)30013-9

    On the analysis of the inverse problem of metabolic pathways using artificial neural networks (Journal article)

    Mendes, P., & Kell, D. B. (1996). On the analysis of the inverse problem of metabolic pathways using artificial neural networks. BIOSYSTEMS, 38(1), 15-28. doi:10.1016/0303-2647(95)01565-5

    DOI: 10.1016/0303-2647(95)01565-5

    Oscillatory, stochastic and chaotic growth rate fluctuations in permittistatically controlled yeast cultures (Journal article)

    Davey, H. M., Davey, C. L., Woodward, A. M., Edmonds, A. N., Lee, A. W., & Kell, D. B. (1996). Oscillatory, stochastic and chaotic growth rate fluctuations in permittistatically controlled yeast cultures. BIOSYSTEMS, 39(1), 43-61. doi:10.1016/0303-2647(95)01577-9

    DOI: 10.1016/0303-2647(95)01577-9

    Plant seed classification using pyrolysis mass spectrometry with unsupervised learning: The application of auto-associative and Kohonen artificial neural networks (Journal article)

    Goodacre, R., Pygall, J., & Kell, D. B. (1996). Plant seed classification using pyrolysis mass spectrometry with unsupervised learning: The application of auto-associative and Kohonen artificial neural networks. CHEMOMETRICS AND INTELLIGENT LABORATORY SYSTEMS, 34(1), 69-83. doi:10.1016/0169-7439(96)00021-4

    DOI: 10.1016/0169-7439(96)00021-4

    Quantitative analysis of multivariate data using artificial neural networks: A tutorial review and applications to the deconvolution of pyrolysis mass spectra (Journal article)

    Goodacre, R., Neal, M. J., & Kell, D. B. (1996). Quantitative analysis of multivariate data using artificial neural networks: A tutorial review and applications to the deconvolution of pyrolysis mass spectra. ZENTRALBLATT FUR BAKTERIOLOGIE-INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY VIROLOGY PARASITOLOGY AND INFECTIOUS DISEASES, 284(4), 516-539. doi:10.1016/S0934-8840(96)80004-1

    DOI: 10.1016/S0934-8840(96)80004-1

    Quantitative analysis of the physiological heterogeneity within starved cultures of Micrococcus luteus by flow cytometry and cell sorting (Journal article)

    Kaprelyants, A. S., Mukamolova, G. V., Davey, H. M., & Kell, D. B. (1996). Quantitative analysis of the physiological heterogeneity within starved cultures of Micrococcus luteus by flow cytometry and cell sorting. APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 62(4), 1311-1316. doi:10.1128/AEM.62.4.1311-1316.1996

    DOI: 10.1128/AEM.62.4.1311-1316.1996

    Rapid and non-invasive quantification of metabolic substrates in biological cell suspensions using non-linear dielectric spectroscopy with multivariate calibration and artificial neural networks. Principles and applications (Conference Paper)

    Woodward, A. M., Jones, A., Zhang, X. Z., Rowland, J., & Kell, D. B. (1996). Rapid and non-invasive quantification of metabolic substrates in biological cell suspensions using non-linear dielectric spectroscopy with multivariate calibration and artificial neural networks. Principles and applications. In BIOELECTROCHEMISTRY AND BIOENERGETICS Vol. 40 (pp. 99-132). doi:10.1016/0302-4598(96)05065-9

    DOI: 10.1016/0302-4598(96)05065-9

    Rapid authentication of animal cell lines using pyrolysis mass spectrometry and auto-associative artificial neural networks (Journal article)

    Goodacre, R., Rischert, D. J., Evans, P. M., & Kell, D. B. (1996). Rapid authentication of animal cell lines using pyrolysis mass spectrometry and auto-associative artificial neural networks. CYTOTECHNOLOGY, 21(3), 231-241. doi:10.1007/BF00365346

    DOI: 10.1007/BF00365346

    1995

    PREPARATION FOR UNIVERSITY (Journal article)

    KELL, D. B. (1995). PREPARATION FOR UNIVERSITY. NATURE, 377(6549), 473. doi:10.1038/377473b0

    DOI: 10.1038/377473b0

    RAPID AND QUANTITATIVE-ANALYSIS OF METABOLITES IN FERMENTER BROTHS USING PYROLYSIS MASS-SPECTROMETRY WITH SUPERVISED LEARNING - APPLICATION TO THE SCREENING OF PENICILLIUM-CHRYSOGENUM FERMENTATIONS FOR THE OVERPRODUCTION OF PENICILLINS (Journal article)

    GOODACRE, R., TREW, S., WRIGLEYJONES, C., SAUNDERS, G., NEAL, M. J., PORTER, N., & KELL, D. B. (1995). RAPID AND QUANTITATIVE-ANALYSIS OF METABOLITES IN FERMENTER BROTHS USING PYROLYSIS MASS-SPECTROMETRY WITH SUPERVISED LEARNING - APPLICATION TO THE SCREENING OF PENICILLIUM-CHRYSOGENUM FERMENTATIONS FOR THE OVERPRODUCTION OF PENICILLINS. ANALYTICA CHIMICA ACTA, 313(1-2), 25-43. doi:10.1016/0003-2670(95)00170-5

    DOI: 10.1016/0003-2670(95)00170-5

    SECRETION OF AN ANTIBACTERIAL FACTOR DURING RESUSCITATION OF DORMANT CELLS IN MICROCOCCUS-LUTEUS CULTURES HELD IN AN EXTENDED STATIONARY-PHASE (Journal article)

    MUKAMOLOVA, G. V., KAPRELYANTS, A. S., & KELL, D. B. (1995). SECRETION OF AN ANTIBACTERIAL FACTOR DURING RESUSCITATION OF DORMANT CELLS IN MICROCOCCUS-LUTEUS CULTURES HELD IN AN EXTENDED STATIONARY-PHASE. ANTONIE VAN LEEUWENHOEK INTERNATIONAL JOURNAL OF GENERAL AND MOLECULAR MICROBIOLOGY, 67(3), 289-295. doi:10.1007/BF00873692

    DOI: 10.1007/BF00873692

    A SERIES OF CASES IN WHICH METABOLIC CHANNELING CAN DECREASE THE POOL SIZE AT CONSTANT NET FLUX IN A SIMPLE DYNAMIC CHANNEL (Conference Paper)

    MENDES, P., KELL, D. B., & WESTERHOFF, H. V. (1995). A SERIES OF CASES IN WHICH METABOLIC CHANNELING CAN DECREASE THE POOL SIZE AT CONSTANT NET FLUX IN A SIMPLE DYNAMIC CHANNEL. In BIOCHEMICAL SOCIETY TRANSACTIONS Vol. 23 (pp. S287). doi:10.1042/bst023287s

    DOI: 10.1042/bst023287s

    BIOCHEMICAL-CHANGES ACCOMPANYING THE LONG-TERM STARVATION OF MICROCOCCUS-LUTEUS CELLS IN SPENT GROWTH-MEDIUM (Journal article)

    MUKAMOLOVA, G. V., YANOPOLSKAYA, N. D., VOTYAKOVA, T. V., POPOV, V. I., KAPRELYANTS, A. S., & KELL, D. B. (1995). BIOCHEMICAL-CHANGES ACCOMPANYING THE LONG-TERM STARVATION OF MICROCOCCUS-LUTEUS CELLS IN SPENT GROWTH-MEDIUM. ARCHIVES OF MICROBIOLOGY, 163(5), 373-379. doi:10.1007/BF00404211

    DOI: 10.1007/BF00404211

    GMP - Good modelling practice: An essential component of good manufacturing practice (Journal article)

    Kell, D. B., & Sonnleitner, B. (1995). GMP - Good modelling practice: An essential component of good manufacturing practice. TRENDS IN BIOTECHNOLOGY, 13(11), 481-492. doi:10.1016/S0167-7799(00)89006-X

    DOI: 10.1016/S0167-7799(00)89006-X

    Metabolic Channeling in Organized Enzyme Systems: Experiments and Models (Journal article)

    Mendes, P., Kell, D. B., & Welch, G. R. (1995). Metabolic Channeling in Organized Enzyme Systems: Experiments and Models. Unknown Journal, 1-19. doi:10.1016/s1569-2558(08)60246-5

    DOI: 10.1016/s1569-2558(08)60246-5

    ON HARMONIC-GENERATION IN NONLINEAR BIOLOGICAL-SYSTEMS (Journal article)

    WOODWARD, A. M., & KELL, D. B. (1995). ON HARMONIC-GENERATION IN NONLINEAR BIOLOGICAL-SYSTEMS. BIOSENSORS & BIOELECTRONICS, 10(6-7), 639-641. doi:10.1016/0956-5663(95)96940-Z

    DOI: 10.1016/0956-5663(95)96940-Z

    PHEROMONES, SOCIAL-BEHAVIOR AND THE FUNCTIONS OF SECONDARY METABOLISM IN BACTERIA (Journal article)

    KELL, D. B., KAPRELYANTS, A. S., & GRAFEN, A. (1995). PHEROMONES, SOCIAL-BEHAVIOR AND THE FUNCTIONS OF SECONDARY METABOLISM IN BACTERIA. TRENDS IN ECOLOGY & EVOLUTION, 10(3), 126-129. doi:10.1016/S0169-5347(00)89013-8

    DOI: 10.1016/S0169-5347(00)89013-8

    SOLVENT SELECTION FOR WHOLE-CELL BIOTRANSFORMATIONS IN ORGANIC MEDIA (Journal article)

    SALTER, G. J., & KELL, D. B. (1995). SOLVENT SELECTION FOR WHOLE-CELL BIOTRANSFORMATIONS IN ORGANIC MEDIA. CRITICAL REVIEWS IN BIOTECHNOLOGY, 15(2), 139-177. doi:10.3109/07388559509147404

    DOI: 10.3109/07388559509147404

    THE USE OF DIELECTRIC PERMITTIVITY FOR THE CONTROL OF THE BIOMASS LEVEL DURING BIOTRANSFORMATIONS OF TOXIC SUBSTRATES IN CONTINUOUS-CULTURE (Journal article)

    MARKX, G. H., & KELL, D. B. (1995). THE USE OF DIELECTRIC PERMITTIVITY FOR THE CONTROL OF THE BIOMASS LEVEL DURING BIOTRANSFORMATIONS OF TOXIC SUBSTRATES IN CONTINUOUS-CULTURE. BIOTECHNOLOGY PROGRESS, 11(1), 64-70. doi:10.1021/bp00031a009

    DOI: 10.1021/bp00031a009

    1994

    RAPID SCREENING FOR METABOLITE OVERPRODUCTION IN FERMENTOR BROTHS, USING PYROLYSIS MASS-SPECTROMETRY WITH MULTIVARIATE CALIBRATION AND ARTIFICIAL NEURAL NETWORKS (Journal article)

    GOODACRE, R., TREW, S., WRIGLEYJONES, C., NEAL, M. J., MADDOCK, J., OTTLEY, T. W., . . . KELL, D. B. (1994). RAPID SCREENING FOR METABOLITE OVERPRODUCTION IN FERMENTOR BROTHS, USING PYROLYSIS MASS-SPECTROMETRY WITH MULTIVARIATE CALIBRATION AND ARTIFICIAL NEURAL NETWORKS. BIOTECHNOLOGY AND BIOENGINEERING, 44(10), 1205-1216. doi:10.1002/bit.260441008

    DOI: 10.1002/bit.260441008

    MORE SUSPECT STATISTICS (Journal article)

    KELL, D. B. (1994). MORE SUSPECT STATISTICS. CHEMISTRY IN BRITAIN, 30(10), 810-&. Retrieved from http://gateway.webofknowledge.com/

    ELECTRODE (Journal article)

    KELL Douglas Bruce., & WOODWARD Andrew Michael. (1994). ELECTRODE.

    Analytical or monitoring apparatus and method (Journal article)

    KELL DOUGLAS B., & WOODWARD ANDREW M. (1994). Analytical or monitoring apparatus and method.

    RAPID AND QUANTITATIVE-ANALYSIS OF RECOMBINANT PROTEIN EXPRESSION USING PYROLYSIS MASS-SPECTROMETRY AND ARTIFICIAL NEURAL NETWORKS - APPLICATION TO MAMMALIAN CYTOCHROME B(5) IN ESCHERICHIA-COLI (Journal article)

    GOODACRE, R., KARIM, A., KADERBHAI, M. A., & KELL, D. B. (1994). RAPID AND QUANTITATIVE-ANALYSIS OF RECOMBINANT PROTEIN EXPRESSION USING PYROLYSIS MASS-SPECTROMETRY AND ARTIFICIAL NEURAL NETWORKS - APPLICATION TO MAMMALIAN CYTOCHROME B(5) IN ESCHERICHIA-COLI. JOURNAL OF BIOTECHNOLOGY, 34(2), 185-193. doi:10.1016/0168-1656(94)90088-4

    DOI: 10.1016/0168-1656(94)90088-4

    DIELECTRIC-PROPERTIES OF HUMAN BLOOD AND ERYTHROCYTES AT RADIO FREQUENCIES (0.2-10-MHZ) - DEPENDENCE ON CELL-VOLUME FRACTION AND MEDIUM COMPOSITION (Journal article)

    BEVING, H., ERIKSSON, L. E. G., DAVEY, C. L., & KELL, D. B. (1994). DIELECTRIC-PROPERTIES OF HUMAN BLOOD AND ERYTHROCYTES AT RADIO FREQUENCIES (0.2-10-MHZ) - DEPENDENCE ON CELL-VOLUME FRACTION AND MEDIUM COMPOSITION. EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS, 23(3), 207-215. doi:10.1007/BF01007612

    DOI: 10.1007/BF01007612

    RAPID AND QUANTITATIVE-ANALYSIS OF THE PYROLYSIS MASS-SPECTRA OF COMPLEX BINARY AND TERTIARY MIXTURES USING MULTIVARIATE CALIBRATION AND ARTIFICIAL NEURAL NETWORKS (Journal article)

    GOODACRE, R., NEAL, M. J., & KELL, D. B. (1994). RAPID AND QUANTITATIVE-ANALYSIS OF THE PYROLYSIS MASS-SPECTRA OF COMPLEX BINARY AND TERTIARY MIXTURES USING MULTIVARIATE CALIBRATION AND ARTIFICIAL NEURAL NETWORKS. ANALYTICAL CHEMISTRY, 66(7), 1070-1085. doi:10.1021/ac00079a024

    DOI: 10.1021/ac00079a024

    ESTIMATION OF DORMANT MICROCOCCUS-LUTEUS CELLS BY PENICILLIN LYSIS AND BY RESUSCITATION IN CELL-FREE SPENT CULTURE-MEDIUM AT HIGH DILUTION (Journal article)

    KAPRELYANTS, A. S., MUKAMOLOVA, G. V., & KELL, D. B. (1994). ESTIMATION OF DORMANT MICROCOCCUS-LUTEUS CELLS BY PENICILLIN LYSIS AND BY RESUSCITATION IN CELL-FREE SPENT CULTURE-MEDIUM AT HIGH DILUTION. FEMS MICROBIOLOGY LETTERS, 115(2-3), 347-352. doi:10.1111/j.1574-6968.1994.tb06662.x

    DOI: 10.1111/j.1574-6968.1994.tb06662.x

    HOW TO VARY THE PROPORTION OF DYNAMIC CHANNELLING FLUX AT CONSTANT TOTAL FLUX (AND DECREASE THE INTERMEDIATE POOL SIZE ...) (Conference Paper)

    MENDES, P., KELL, D. B., & WESTERHOFF, H. V. (1994). HOW TO VARY THE PROPORTION OF DYNAMIC CHANNELLING FLUX AT CONSTANT TOTAL FLUX (AND DECREASE THE INTERMEDIATE POOL SIZE ...). In WHAT IS CONTROLLING LIFE? Vol. 3 (pp. 202-203). Retrieved from http://gateway.webofknowledge.com/

    INFLUENCE OF VIABLE CELLS ON THE RESUSCITATION OF DORMANT CELLS IN MICROCOCCUS-LUTEUS CULTURES HELD IN AN EXTENDED STATIONARY-PHASE - THE POPULATION EFFECT (Journal article)

    VOTYAKOVA, T. V., KAPRELYANTS, A. S., & KELL, D. B. (1994). INFLUENCE OF VIABLE CELLS ON THE RESUSCITATION OF DORMANT CELLS IN MICROCOCCUS-LUTEUS CULTURES HELD IN AN EXTENDED STATIONARY-PHASE - THE POPULATION EFFECT. APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 60(9), 3284-3291. doi:10.1128/AEM.60.9.3284-3291.1994

    DOI: 10.1128/AEM.60.9.3284-3291.1994

    LIFE, DEATH, DORMANCY AND SOCIAL RESUSCITATION IN NON-SPORULATING BACTERIA - RELATIONSHIPS WITH THE ENERGETIC STATUS OF INDIVIDUAL CELLS (Conference Paper)

    KELL, D. B., DAVEY, H. M., MUKAMOLOVA, G. V., VOTYAKOVA, T. V., & KAPRELYANTS, A. S. (1994). LIFE, DEATH, DORMANCY AND SOCIAL RESUSCITATION IN NON-SPORULATING BACTERIA - RELATIONSHIPS WITH THE ENERGETIC STATUS OF INDIVIDUAL CELLS. In WHAT IS CONTROLLING LIFE? Vol. 3 (pp. 252-254). Retrieved from http://gateway.webofknowledge.com/

    ON THE ANALYSIS OF PYROLYSIS MASS-SPECTRA USING ARTIFICIAL NEURAL NETWORKS - INDIVIDUAL INPUT SCALING LEADS TO RAPID LEARNING (Conference Paper)

    NEAL, M. J., GOODACRE, R., KELL, D. B., & SOC, I. N. T. N. N. (1994). ON THE ANALYSIS OF PYROLYSIS MASS-SPECTRA USING ARTIFICIAL NEURAL NETWORKS - INDIVIDUAL INPUT SCALING LEADS TO RAPID LEARNING. In WORLD CONGRESS ON NEURAL NETWORKS-SAN DIEGO - 1994 INTERNATIONAL NEURAL NETWORK SOCIETY ANNUAL MEETING, VOL 1 (pp. A318-A323). Retrieved from http://gateway.webofknowledge.com/

    RAPID IDENTIFICATION USING PYROLYSIS MASS-SPECTROMETRY AND ARTIFICIAL NEURAL NETWORKS OF PROPIONIBACTERIUM-ACNES ISOLATED FROM DOGS (Journal article)

    GOODACRE, R., NEAL, M. J., KELL, D. B., GREENHAM, L. W., NOBLE, W. C., & HARVEY, R. G. (1994). RAPID IDENTIFICATION USING PYROLYSIS MASS-SPECTROMETRY AND ARTIFICIAL NEURAL NETWORKS OF PROPIONIBACTERIUM-ACNES ISOLATED FROM DOGS. JOURNAL OF APPLIED BACTERIOLOGY, 76(2), 124-134. doi:10.1111/j.1365-2672.1994.tb01607.x

    DOI: 10.1111/j.1365-2672.1994.tb01607.x

    SIMULTANEOUS ESTIMATES OF SINGLE-ENZYME KINETIC PARAMETERS FOR MULTI-ENZYMATIC SYSTEMS USING ARTIFICIAL NEURAL NETWORKS (Conference Paper)

    MENDES, P., & KELL, D. B. (1994). SIMULTANEOUS ESTIMATES OF SINGLE-ENZYME KINETIC PARAMETERS FOR MULTI-ENZYMATIC SYSTEMS USING ARTIFICIAL NEURAL NETWORKS. In WHAT IS CONTROLLING LIFE? Vol. 3 (pp. 302-304). Retrieved from http://gateway.webofknowledge.com/

    THE DOGS THAT DID NOT BARK (Journal article)

    KELL, D. B., GOODACRE, R., & NEAL, M. J. (1994). THE DOGS THAT DID NOT BARK. TRENDS IN BIOTECHNOLOGY, 12(11), 434-435. doi:10.1016/0167-7799(94)90016-7

    DOI: 10.1016/0167-7799(94)90016-7

    1993

    INTRODUCTION TO THE DIELECTRIC ESTIMATION OF CELLULAR BIOMASS IN REAL-TIME, WITH SPECIAL EMPHASIS ON MEASUREMENTS AT HIGH-VOLUME FRACTIONS (Conference Paper)

    DAVEY, C. L., DAVEY, H. M., KELL, D. B., & TODD, R. W. (1993). INTRODUCTION TO THE DIELECTRIC ESTIMATION OF CELLULAR BIOMASS IN REAL-TIME, WITH SPECIAL EMPHASIS ON MEASUREMENTS AT HIGH-VOLUME FRACTIONS. In ANALYTICA CHIMICA ACTA Vol. 279 (pp. 155-161). doi:10.1016/0003-2670(93)85078-X

    DOI: 10.1016/0003-2670(93)85078-X

    RAPID AND QUANTITATIVE-ANALYSIS OF BIOPROCESSES USING PYROLYSIS MASS-SPECTROMETRY AND NEURAL NETWORKS - APPLICATION TO INDOLE PRODUCTION (Conference Paper)

    GOODACRE, R., & KELL, D. B. (1993). RAPID AND QUANTITATIVE-ANALYSIS OF BIOPROCESSES USING PYROLYSIS MASS-SPECTROMETRY AND NEURAL NETWORKS - APPLICATION TO INDOLE PRODUCTION. In ANALYTICA CHIMICA ACTA Vol. 279 (pp. 17-26). doi:10.1016/0003-2670(93)85062-O

    DOI: 10.1016/0003-2670(93)85062-O

    ON THE ROLE OF ENZYME-KINETIC PARAMETERS IN DETERMINING THE EFFECTIVENESS WITH WHICH CHANNELING CAN DECREASE THE SIZE OF A METABOLITE POOL (Journal article)

    MENDES, P., & KELL, D. B. (1993). ON THE ROLE OF ENZYME-KINETIC PARAMETERS IN DETERMINING THE EFFECTIVENESS WITH WHICH CHANNELING CAN DECREASE THE SIZE OF A METABOLITE POOL. ACTA BIOTHEORETICA, 41(1-2), 63-73. doi:10.1007/BF00712775

    DOI: 10.1007/BF00712775

    Dormancy in non-sporulating bacteria (Journal article)

    Kaprelyants, A. S., Gottschal, J. C., & Kell, D. B. (1993). Dormancy in non-sporulating bacteria. FEMS Microbiology Letters, 104(3-4), 271-286. doi:10.1111/j.1574-6968.1993.tb05871.x

    DOI: 10.1111/j.1574-6968.1993.tb05871.x

    ANALYTICAL OR MONITORING APPARATUS AND METHOD (Journal article)

    KELL Douglas Bruce., & WOODWARD Andrew Michael. (1993). ANALYTICAL OR MONITORING APPARATUS AND METHOD.

    ANALYTICAL OR MONITORING APPARATUS AND METHOD (Journal article)

    KELL Douglas Bruce., & WOODWARD Andrew Michael. (1993). ANALYTICAL OR MONITORING APPARATUS AND METHOD.

    CONTROL ANALYSIS OF METABOLIC CHANNELING (Conference Paper)

    MENDES, P., & KELL, D. B. (1993). CONTROL ANALYSIS OF METABOLIC CHANNELING. In MODERN TRENDS IN BIOTHERMOKINETICS (pp. 211-216). Retrieved from http://gateway.webofknowledge.com/

    DORMANCY IN NON-SPORULATING BACTERIA (Journal article)

    KAPRELYANTS, A. S., GOTTSCHAL, J. C., & KELL, D. B. (1993). DORMANCY IN NON-SPORULATING BACTERIA. FEMS MICROBIOLOGY LETTERS, 104(3-4), 271-286. doi:10.1016/0378-1097(93)90600-7

    DOI: 10.1016/0378-1097(93)90600-7

    DORMANCY IN STATIONARY-PHASE CULTURES OF MICROCOCCUS-LUTEUS - FLOW CYTOMETRIC ANALYSIS OF STARVATION AND RESUSCITATION (Journal article)

    KAPRELYANTS, A. S., & KELL, D. B. (1993). DORMANCY IN STATIONARY-PHASE CULTURES OF MICROCOCCUS-LUTEUS - FLOW CYTOMETRIC ANALYSIS OF STARVATION AND RESUSCITATION. APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 59(10), 3187-3196. doi:10.1128/AEM.59.10.3187-3196.1993

    DOI: 10.1128/AEM.59.10.3187-3196.1993

    ON THE DIELECTRIC METHOD OF MONITORING CELLULAR VIABILITY (Conference Paper)

    DAVEY, C. L., MARKX, G. H., & KELL, D. B. (1993). ON THE DIELECTRIC METHOD OF MONITORING CELLULAR VIABILITY. In PURE AND APPLIED CHEMISTRY Vol. 65 (pp. 1921-1926). doi:10.1351/pac199365091921

    DOI: 10.1351/pac199365091921

    PHYSICS WITHOUT TEARS (Journal article)

    KELL, D. B. (1993). PHYSICS WITHOUT TEARS. PHYSICS WORLD, 6(1), 19. doi:10.1088/2058-7058/6/1/12

    DOI: 10.1088/2058-7058/6/1/12

    QUANTITATIVE-ANALYSIS OF THE PYROLYSIS MASS-SPECTRA OF COMPLEX-MIXTURES USING ARTIFICIAL NEURAL NETWORKS - APPLICATION TO AMINO-ACIDS IN GLYCOGEN (Journal article)

    GOODACRE, R., EDMONDS, A. N., & KELL, D. B. (1993). QUANTITATIVE-ANALYSIS OF THE PYROLYSIS MASS-SPECTRA OF COMPLEX-MIXTURES USING ARTIFICIAL NEURAL NETWORKS - APPLICATION TO AMINO-ACIDS IN GLYCOGEN. JOURNAL OF ANALYTICAL AND APPLIED PYROLYSIS, 26(2), 93-114. doi:10.1016/0165-2370(93)85020-Y

    DOI: 10.1016/0165-2370(93)85020-Y

    RAPID ASSESSMENT OF THE ADULTERATION OF VIRGIN OLIVE OILS BY OTHER SEED OILS USING PYROLYSIS MASS-SPECTROMETRY AND ARTIFICIAL NEURAL NETWORKS (Journal article)

    GOODACRE, R., KELL, D. B., & BIANCHI, G. (1993). RAPID ASSESSMENT OF THE ADULTERATION OF VIRGIN OLIVE OILS BY OTHER SEED OILS USING PYROLYSIS MASS-SPECTROMETRY AND ARTIFICIAL NEURAL NETWORKS. JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE, 63(3), 297-307. doi:10.1002/jsfa.2740630306

    DOI: 10.1002/jsfa.2740630306

    THE USE OF 5-CYANO-2,3-DITOLYL TETRAZOLIUM CHLORIDE AND FLOW-CYTOMETRY FOR THE VISUALIZATION OF RESPIRATORY ACTIVITY IN INDIVIDUAL CELLS OF MICROCOCCUS-LUTEUS (Journal article)

    KAPRELYANTS, A. S., & KELL, D. B. (1993). THE USE OF 5-CYANO-2,3-DITOLYL TETRAZOLIUM CHLORIDE AND FLOW-CYTOMETRY FOR THE VISUALIZATION OF RESPIRATORY ACTIVITY IN INDIVIDUAL CELLS OF MICROCOCCUS-LUTEUS. JOURNAL OF MICROBIOLOGICAL METHODS, 17(2), 115-122. doi:10.1016/0167-7012(93)90004-2

    DOI: 10.1016/0167-7012(93)90004-2

    WHEN GOING BACKWARDS MEANS PROGRESS - ON THE SOLUTION OF BIOCHEMICAL INVERSE PROBLEMS USING ARTIFICIAL NEURAL NETWORKS (Conference Paper)

    KELL, D. B., DAVEY, C. L., GOODACRE, R., & SAURO, H. M. (1993). WHEN GOING BACKWARDS MEANS PROGRESS - ON THE SOLUTION OF BIOCHEMICAL INVERSE PROBLEMS USING ARTIFICIAL NEURAL NETWORKS. In MODERN TRENDS IN BIOTHERMOKINETICS (pp. 109-114). Retrieved from http://gateway.webofknowledge.com/

    1992

    NEURAL NETWORKS AND OLIVE OIL (Journal article)

    GOODACRE, R., KELL, D. B., & BIANCHI, G. (1992). NEURAL NETWORKS AND OLIVE OIL. NATURE, 359(6396), 594. doi:10.1038/359594a0

    DOI: 10.1038/359594a0

    CHANNELING CAN DECREASE POOL SIZE (Journal article)

    MENDES, P., KELL, D. B., & WESTERHOFF, H. V. (1992). CHANNELING CAN DECREASE POOL SIZE. EUROPEAN JOURNAL OF BIOCHEMISTRY, 204(1), 257-266. doi:10.1111/j.1432-1033.1992.tb16632.x

    DOI: 10.1111/j.1432-1033.1992.tb16632.x

    NONLINEAR DIELECTRIC-PROPERTIES OF RHODOBACTER-CAPSULATUS (Journal article)

    MCSHEA, A., WOODWARD, A. M., & KELL, D. B. (1992). NONLINEAR DIELECTRIC-PROPERTIES OF RHODOBACTER-CAPSULATUS. BIOELECTROCHEMISTRY AND BIOENERGETICS, 29(2), 205-214. doi:10.1016/0302-4598(92)80068-R

    DOI: 10.1016/0302-4598(92)80068-R

    New materials and technology for cell immobilization. (Journal article)

    Salter, G. J., & Kell, D. B. (1992). New materials and technology for cell immobilization.. Current opinion in biotechnology, 3(2), 115-118. doi:10.1016/0958-1669(92)90138-9

    DOI: 10.1016/0958-1669(92)90138-9

    ON FITTING DIELECTRIC SPECTRA USING ARTIFICIAL NEURAL NETWORKS (Journal article)

    KELL, D. B., & DAVEY, C. L. (1992). ON FITTING DIELECTRIC SPECTRA USING ARTIFICIAL NEURAL NETWORKS. BIOELECTROCHEMISTRY AND BIOENERGETICS, 28(3), 425-434. doi:10.1016/0302-4598(92)80030-K

    DOI: 10.1016/0302-4598(92)80030-K

    ON THE DIELECTRIC-PROPERTIES OF CELL-SUSPENSIONS AT HIGH-VOLUME FRACTIONS (Journal article)

    DAVEY, C. L., DAVEY, H. M., & KELL, D. B. (1992). ON THE DIELECTRIC-PROPERTIES OF CELL-SUSPENSIONS AT HIGH-VOLUME FRACTIONS. BIOELECTROCHEMISTRY AND BIOENERGETICS, 28(1-2), 319-340. doi:10.1016/0302-4598(92)80023-A

    DOI: 10.1016/0302-4598(92)80023-A

    On fitting dielectric spectra using artificial neural networks (Journal article)

    Kell, D. B., & Davey, C. L. (1992). On fitting dielectric spectra using artificial neural networks. Journal of Electroanalytical Chemistry, 343(3), 425-434. doi:10.1016/0022-0728(92)85104-b

    DOI: 10.1016/0022-0728(92)85104-b

    On the dielectric properties of cell suspensions at high volume fractions (Journal article)

    Davey, C. L., Davey, H. M., & Kell, D. B. (1992). On the dielectric properties of cell suspensions at high volume fractions. Journal of Electroanalytical Chemistry, 343(1-2), 319-340. doi:10.1016/0022-0728(92)85097-m

    DOI: 10.1016/0022-0728(92)85097-m

    PHYSIOLOGICAL-STUDIES ON THE SOLID-STATE QUINOA TEMPE FERMENTATION, USING ONLINE MEASUREMENTS OF FUNGAL BIOMASS PRODUCTION (Journal article)

    PENALOZA, W., DAVEY, C. L., HEDGER, J. N., & KELL, D. B. (1992). PHYSIOLOGICAL-STUDIES ON THE SOLID-STATE QUINOA TEMPE FERMENTATION, USING ONLINE MEASUREMENTS OF FUNGAL BIOMASS PRODUCTION. JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE, 59(2), 227-235. doi:10.1002/jsfa.2740590214

    DOI: 10.1002/jsfa.2740590214

    RAPID ASSESSMENT OF BACTERIAL VIABILITY AND VITALITY BY RHODAMINE 123 AND FLOW-CYTOMETRY (Journal article)

    KAPRELYANTS, A. S., & KELL, D. B. (1992). RAPID ASSESSMENT OF BACTERIAL VIABILITY AND VITALITY BY RHODAMINE 123 AND FLOW-CYTOMETRY. JOURNAL OF APPLIED BACTERIOLOGY, 72(5), 410-422. doi:10.1111/j.1365-2672.1992.tb01854.x

    DOI: 10.1111/j.1365-2672.1992.tb01854.x

    RAPID-DETERMINATION, USING DIELECTRIC-SPECTROSCOPY, OF THE TOXICITY OF ORGANIC-SOLVENTS TO INTACT-CELLS (Conference Paper)

    SALTER, G. J., & KELL, D. B. (1992). RAPID-DETERMINATION, USING DIELECTRIC-SPECTROSCOPY, OF THE TOXICITY OF ORGANIC-SOLVENTS TO INTACT-CELLS. In BIOCATALYSIS IN NON-CONVENTIONAL MEDIA Vol. 8 (pp. 291-297). Retrieved from http://gateway.webofknowledge.com/

    SCANNING TUNNELING MICROSCOPY IN BIOLOGY - ARE THE CURRENT CARRIERS TUNNELING ELECTRONS OR HYDRATED PROTONS (Journal article)

    KELL, D. B. (1992). SCANNING TUNNELING MICROSCOPY IN BIOLOGY - ARE THE CURRENT CARRIERS TUNNELING ELECTRONS OR HYDRATED PROTONS. BIOELECTROCHEMISTRY AND BIOENERGETICS, 27(2), 235-237. doi:10.1016/0302-4598(92)87047-X

    DOI: 10.1016/0302-4598(92)87047-X

    Scanning tunnelling microscopy in biology (Journal article)

    Kell, D. B. (1992). Scanning tunnelling microscopy in biology. Journal of Electroanalytical Chemistry, 342(2), 235-237. doi:10.1016/0022-0728(92)85054-7

    DOI: 10.1016/0022-0728(92)85054-7

    THE PROTONMOTIVE FORCE AS AN INTERMEDIATE IN ELECTRON TRANSPORT-LINKED PHOSPHORYLATION - PROBLEMS AND PROSPECTS (Journal article)

    KELL, D. B. (1992). THE PROTONMOTIVE FORCE AS AN INTERMEDIATE IN ELECTRON TRANSPORT-LINKED PHOSPHORYLATION - PROBLEMS AND PROSPECTS. CURRENT TOPICS IN CELLULAR REGULATION, 33, 279-289. Retrieved from http://gateway.webofknowledge.com/

    1991

    CONFIRMATION BY USING MUTANT STRAINS THAT THE MEMBRANE-BOUND H+-ATPASE IS THE MAJOR SOURCE OF NONLINEAR DIELECTRICITY IN SACCHAROMYCES-CEREVISIAE (Journal article)

    WOODWARD, A. M., & KELL, D. B. (1991). CONFIRMATION BY USING MUTANT STRAINS THAT THE MEMBRANE-BOUND H+-ATPASE IS THE MAJOR SOURCE OF NONLINEAR DIELECTRICITY IN SACCHAROMYCES-CEREVISIAE. FEMS MICROBIOLOGY LETTERS, 84(1), 91-95. Retrieved from http://gateway.webofknowledge.com/

    Confirmation by using mutant strains that the membrane-bound H(+)-ATPase is the major source of non-linear dielectricity in Saccharomyces cerevisiae. (Journal article)

    Woodward, A. M., & Kell, D. B. (1991). Confirmation by using mutant strains that the membrane-bound H(+)-ATPase is the major source of non-linear dielectricity in Saccharomyces cerevisiae.. FEMS microbiology letters, 68(1), 91-95. doi:10.1016/0378-1097(91)90401-u

    DOI: 10.1016/0378-1097(91)90401-u

    ON THE PHYSIOLOGICAL SIGNIFICANCE OF METABOLITE CHANNELING - IF, HOW, AND WHERE, BUT NOT WHY (Journal article)

    KELL, D. B. (1991). ON THE PHYSIOLOGICAL SIGNIFICANCE OF METABOLITE CHANNELING - IF, HOW, AND WHERE, BUT NOT WHY. JOURNAL OF THEORETICAL BIOLOGY, 152(1), 49-51. doi:10.1016/S0022-5193(05)80508-9

    DOI: 10.1016/S0022-5193(05)80508-9

    QUANTIFYING HETEROGENEITY - FLOW-CYTOMETRY OF BACTERIAL CULTURES (Journal article)

    KELL, D. B., RYDER, H. M., KAPRELYANTS, A. S., & WESTERHOFF, H. V. (1991). QUANTIFYING HETEROGENEITY - FLOW-CYTOMETRY OF BACTERIAL CULTURES. ANTONIE VAN LEEUWENHOEK INTERNATIONAL JOURNAL OF GENERAL AND MOLECULAR MICROBIOLOGY, 60(3-4), 145-158. doi:10.1007/BF00430362

    DOI: 10.1007/BF00430362

    QUANTITATIVE APPROACHES TO THE ANALYSIS OF THE CONTROL AND REGULATION OF MICROBIAL-METABOLISM (Journal article)

    WESTERHOFF, H. V., VANHEESWIJK, W., KAHN, D., & KELL, D. B. (1991). QUANTITATIVE APPROACHES TO THE ANALYSIS OF THE CONTROL AND REGULATION OF MICROBIAL-METABOLISM. ANTONIE VAN LEEUWENHOEK INTERNATIONAL JOURNAL OF GENERAL AND MOLECULAR MICROBIOLOGY, 60(3-4), 193-207. doi:10.1007/BF00430365

    DOI: 10.1007/BF00430365

    ANALYTICAL METHOD (Journal article)

    KELL Douglas Bruce Symlog House., & WOODWARD Andrew Michael Calidris Newborough. (1991). ANALYTICAL METHOD.

    ANALYTICAL METHOD (Journal article)

    KELL Douglas Bruce., & WOODWARD Andrew Michael. (1991). ANALYTICAL METHOD.

    THE PERMITTISTAT - A NOVEL TYPE OF TURBIDOSTAT (Journal article)

    MARKX, G. H., DAVEY, C. L., & KELL, D. B. (1991). THE PERMITTISTAT - A NOVEL TYPE OF TURBIDOSTAT. JOURNAL OF GENERAL MICROBIOLOGY, 137, 735-743. doi:10.1099/00221287-137-4-735

    DOI: 10.1099/00221287-137-4-735

    LACUNA SEEKER (Journal article)

    KELL, D. B. (1991). LACUNA SEEKER. NATURE, 350(6316), 268. doi:10.1038/350268e0

    DOI: 10.1038/350268e0

    REAL-TIME MONITORING OF THE ACCRETION OF RHIZOPUS-OLIGOSPORUS BIOMASS DURING THE SOLID-SUBSTRATE TEMPE FERMENTATION (Journal article)

    DAVEY, C. L., PENALOZA, W., KELL, D. B., & HEDGER, J. N. (1991). REAL-TIME MONITORING OF THE ACCRETION OF RHIZOPUS-OLIGOSPORUS BIOMASS DURING THE SOLID-SUBSTRATE TEMPE FERMENTATION. WORLD JOURNAL OF MICROBIOLOGY & BIOTECHNOLOGY, 7(2), 248-259. doi:10.1007/BF00328998

    DOI: 10.1007/BF00328998

    STIMULATION BY POTASSIUM-IONS OF THE GROWTH OF RHIZOPUS-OLIGOSPORUS DURING LIQUID-SUBSTRATE AND SOLID-SUBSTRATE FERMENTATIONS (Journal article)

    PENALOZA, W., DAVEY, C. L., HEDGER, J. N., & KELL, D. B. (1991). STIMULATION BY POTASSIUM-IONS OF THE GROWTH OF RHIZOPUS-OLIGOSPORUS DURING LIQUID-SUBSTRATE AND SOLID-SUBSTRATE FERMENTATIONS. WORLD JOURNAL OF MICROBIOLOGY & BIOTECHNOLOGY, 7(2), 260-268. doi:10.1007/BF00328999

    DOI: 10.1007/BF00328999

    DUAL-FREQUENCY EXCITATION - A NOVEL METHOD FOR PROBING THE NONLINEAR DIELECTRIC-PROPERTIES OF BIOLOGICAL-SYSTEMS, AND ITS APPLICATION TO SUSPENSIONS OF SACCHAROMYCES-CEREVISIAE (Journal article)

    WOODWARD, A. M., & KELL, D. B. (1991). DUAL-FREQUENCY EXCITATION - A NOVEL METHOD FOR PROBING THE NONLINEAR DIELECTRIC-PROPERTIES OF BIOLOGICAL-SYSTEMS, AND ITS APPLICATION TO SUSPENSIONS OF SACCHAROMYCES-CEREVISIAE. BIOELECTROCHEMISTRY AND BIOENERGETICS, 25(3), 395-413. doi:10.1016/0302-4598(91)80005-N

    DOI: 10.1016/0302-4598(91)80005-N

    Dual-frequency excitation: a novel method for probing the nonlinear dielectric properties of biological systems, and its application to suspensions of S. cerevisiae (Journal article)

    Woodward, A. M., & Kell, D. B. (1991). Dual-frequency excitation: a novel method for probing the nonlinear dielectric properties of biological systems, and its application to suspensions of S. cerevisiae. Journal of Electroanalytical Chemistry and Interfacial Electrochemistry, 320(3), 395-413. doi:10.1016/0022-0728(91)85655-9

    DOI: 10.1016/0022-0728(91)85655-9

    NEW MATERIALS AND TECHNOLOGY FOR CELL IMMOBILIZATION (Journal article)

    SALTER, G. J., & KELL, D. B. (1991). NEW MATERIALS AND TECHNOLOGY FOR CELL IMMOBILIZATION. CURRENT OPINION IN BIOTECHNOLOGY, 2(3), 385-389. doi:10.1016/S0958-1669(05)80143-0

    DOI: 10.1016/S0958-1669(05)80143-0

    Non-Faradaic electrochemical sensors: principles and practice (Journal article)

    Kell, D. B., Woodward, A. M., Cade, N. J., Gibbs, T. K., Iredale, P. J., & Williams, D. A. (1991). Non-Faradaic electrochemical sensors: principles and practice. Analytical Proceedings, 28(11), 378. doi:10.1039/ap9912800378

    DOI: 10.1039/ap9912800378

    ON THE RELATIONSHIP BETWEEN THE NONLINEAR DIELECTRIC-PROPERTIES AND RESPIRATORY ACTIVITY OF THE OBLIGATELY AEROBIC BACTERIUM MICROCOCCUS-LUTEUS (Journal article)

    WOODWARD, A. M., & KELL, D. B. (1991). ON THE RELATIONSHIP BETWEEN THE NONLINEAR DIELECTRIC-PROPERTIES AND RESPIRATORY ACTIVITY OF THE OBLIGATELY AEROBIC BACTERIUM MICROCOCCUS-LUTEUS. BIOELECTROCHEMISTRY AND BIOENERGETICS, 26(3), 423-439. doi:10.1016/0302-4598(91)85005-M

    DOI: 10.1016/0302-4598(91)85005-M

    On the relationship between the nonlinear dielectric properties and respiratory activity of the obligately aerobic bacterium Micrococcus luteus (Journal article)

    Woodward, A. M., & Kell, D. B. (1991). On the relationship between the nonlinear dielectric properties and respiratory activity of the obligately aerobic bacterium Micrococcus luteus. Journal of Electroanalytical Chemistry and Interfacial Electrochemistry, 321(3), 423-439. doi:10.1016/0022-0728(91)85643-4

    DOI: 10.1016/0022-0728(91)85643-4

    Solutions, but no answers (Journal article)

    Kell, D. B. (1991). Solutions, but no answers. Trends in Biochemical Sciences, 16, 164. doi:10.1016/0968-0004(91)90062-z

    DOI: 10.1016/0968-0004(91)90062-z

    THE DIELECTRIC PERMITTIVITY AT RADIO FREQUENCIES AND THE BRUGGEMAN PROBE - NOVEL TECHNIQUES FOR THE ONLINE DETERMINATION OF BIOMASS CONCENTRATIONS IN PLANT-CELL CULTURES (Journal article)

    MARKX, G. H., DAVEY, C. L., KELL, D. B., & MORRIS, P. (1991). THE DIELECTRIC PERMITTIVITY AT RADIO FREQUENCIES AND THE BRUGGEMAN PROBE - NOVEL TECHNIQUES FOR THE ONLINE DETERMINATION OF BIOMASS CONCENTRATIONS IN PLANT-CELL CULTURES. JOURNAL OF BIOTECHNOLOGY, 20(3), 279-290. doi:10.1016/0168-1656(91)90337-U

    DOI: 10.1016/0168-1656(91)90337-U

    TO WHAT EXTENT IS THE MAGNITUDE OF THE COLE-COLE-ALPHA OF THE BETA-DIELECTRIC DISPERSION OF CELL-SUSPENSIONS EXPLICABLE IN TERMS OF THE CELL-SIZE DISTRIBUTION (Journal article)

    MARKX, G. H., DAVEY, C. L., & KELL, D. B. (1991). TO WHAT EXTENT IS THE MAGNITUDE OF THE COLE-COLE-ALPHA OF THE BETA-DIELECTRIC DISPERSION OF CELL-SUSPENSIONS EXPLICABLE IN TERMS OF THE CELL-SIZE DISTRIBUTION. BIOELECTROCHEMISTRY AND BIOENERGETICS, 25(2), 195-211. doi:10.1016/0302-4598(91)87003-Y

    DOI: 10.1016/0302-4598(91)87003-Y

    To what extent is the magnitude of the Cole—Cole a of the ß-dielectric dispersion of cell suspensions explicable in terms of the cell size distribution? (Journal article)

    Markx, G. H., Davey, C. L., & Kell, D. B. (1991). To what extent is the magnitude of the Cole—Cole a of the ß-dielectric dispersion of cell suspensions explicable in terms of the cell size distribution?. Journal of Electroanalytical Chemistry and Interfacial Electrochemistry, 320(2), 195-211. doi:10.1016/0022-0728(91)85627-2

    DOI: 10.1016/0022-0728(91)85627-2

    1990

    Dielectric spectroscopy as a tool for the measurement of the formation of biofilms and of their removal by electrolytic cleaning pulses and biocides (Journal article)

    Markx, G. H., & Kell, D. B. (1990). Dielectric spectroscopy as a tool for the measurement of the formation of biofilms and of their removal by electrolytic cleaning pulses and biocides. Biofouling, 2(3), 211-227. doi:10.1080/08927019009378146

    DOI: 10.1080/08927019009378146

    EVIDENCE FROM ITS TEMPERATURE-DEPENDENCE THAT THE BETA-DIELECTRIC DISPERSION OF CELL-SUSPENSIONS IS NOT DUE SOLELY TO THE CHARGING OF A STATIC MEMBRANE CAPACITANCE (Journal article)

    FERRIS, L. E., DAVEY, C. L., & KELL, D. B. (1990). EVIDENCE FROM ITS TEMPERATURE-DEPENDENCE THAT THE BETA-DIELECTRIC DISPERSION OF CELL-SUSPENSIONS IS NOT DUE SOLELY TO THE CHARGING OF A STATIC MEMBRANE CAPACITANCE. EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS, 18(5), 267-276. Retrieved from http://gateway.webofknowledge.com/

    SUBSTITUTION AND SPREADSHEET METHODS FOR ANALYZING DIELECTRIC SPECTRA OF BIOLOGICAL-SYSTEMS (Journal article)

    DAVEY, C. L., MARKX, G. H., & KELL, D. B. (1990). SUBSTITUTION AND SPREADSHEET METHODS FOR ANALYZING DIELECTRIC SPECTRA OF BIOLOGICAL-SYSTEMS. EUROPEAN BIOPHYSICS JOURNAL, 18(5), 255-265. Retrieved from http://gateway.webofknowledge.com/

    Determination of biomass (Journal article)

    KELL DOUGLAS B. (1990). Determination of biomass.

    CONTROL ANALYSIS OF ORGANIZED MULTIENZYME SYSTEMS (Conference Paper)

    KELL, D. B., & WESTERHOFF, H. V. (1990). CONTROL ANALYSIS OF ORGANIZED MULTIENZYME SYSTEMS. In STRUCTURAL AND ORGANIZATIONAL ASPECTS OF METABOLIC REGULATION Vol. 133 (pp. 273-289). Retrieved from http://gateway.webofknowledge.com/

    ELECTROMICROBIAL AND RELATED APPROACHES TO ANAEROBIC BIOTRANSFORMATIONS (Conference Paper)

    JAMES, E. W., DIXON, N. M., DENHOLM, A. M., KELL, D. B., & MORRIS, J. G. (1990). ELECTROMICROBIAL AND RELATED APPROACHES TO ANAEROBIC BIOTRANSFORMATIONS. In OPPORTUNITIES IN BIOTRANSFORMATIONS (pp. 195-202). Retrieved from http://gateway.webofknowledge.com/

    HYDRODYNAMIC DEPOSITION - A NOVEL METHOD OF CELL IMMOBILIZATION (Journal article)

    SALTER, G. J., KELL, D. B., ASH, L. A., ADAMS, J. M., BROWN, A. J., & JAMES, R. (1990). HYDRODYNAMIC DEPOSITION - A NOVEL METHOD OF CELL IMMOBILIZATION. ENZYME AND MICROBIAL TECHNOLOGY, 12(6), 419-430. doi:10.1016/0141-0229(90)90052-R

    DOI: 10.1016/0141-0229(90)90052-R

    ON THE NONLINEAR DIELECTRIC-PROPERTIES OF BIOLOGICAL-SYSTEMS SACCHAROMYCES-CEREVISIAE (Journal article)

    WOODWARD, A. M., & KELL, D. B. (1990). ON THE NONLINEAR DIELECTRIC-PROPERTIES OF BIOLOGICAL-SYSTEMS SACCHAROMYCES-CEREVISIAE. BIOELECTROCHEMISTRY AND BIOENERGETICS, 24(2), 83-100. doi:10.1016/0302-4598(90)85013-8

    DOI: 10.1016/0302-4598(90)85013-8

    On the nonlinear dielectric properties of biological systems (Journal article)

    Woodward, A. M., & Kell, D. B. (1990). On the nonlinear dielectric properties of biological systems. Journal of Electroanalytical Chemistry and Interfacial Electrochemistry, 299(2), 83-100. doi:10.1016/0022-0728(90)87511-h

    DOI: 10.1016/0022-0728(90)87511-h

    REAL-TIME MONITORING OF CELLULAR BIOMASS - METHODS AND APPLICATIONS (Journal article)

    KELL, D. B., MARKX, G. H., DAVEY, C. L., & TODD, R. W. (1990). REAL-TIME MONITORING OF CELLULAR BIOMASS - METHODS AND APPLICATIONS. TRAC-TRENDS IN ANALYTICAL CHEMISTRY, 9(6), 190-194. Retrieved from http://gateway.webofknowledge.com/

    1989

    Immobilization of Candida cylindracea lipase on a new range of ceramic supports. (Journal article)

    Walter, R. P., Kell, D. B., Morris, J. G., James, R., & Adams, J. M. (1990). Immobilization of Candida cylindracea lipase on a new range of ceramic supports.. Biotechnology techniques., 3(5), 345-348. doi:10.1007/bf01875634

    DOI: 10.1007/bf01875634

    WINDOW BOXES (Journal article)

    KELL, D. B. (1989). WINDOW BOXES. NATURE, 338(6217), 612. doi:10.1038/338612c0

    DOI: 10.1038/338612c0

    CONTROL ANALYSIS OF MICROBIAL-GROWTH AND PRODUCTIVITY (Conference Paper)

    KELL, D. B., VANDAM, K., & WESTERHOFF, H. V. (1989). CONTROL ANALYSIS OF MICROBIAL-GROWTH AND PRODUCTIVITY. In MICROBIAL PRODUCTS : NEW APPROACHES Vol. 44 (pp. 61-93). Retrieved from http://gateway.webofknowledge.com/

    Dielectric Spectroscopy: a Rapid Method for the Determination of Solvent Biocompatibility During Biotransformations (Journal article)

    Stoicheva, N. G., Davey, C. L., Markx, G. H., & Kell, D. B. (1989). Dielectric Spectroscopy: a Rapid Method for the Determination of Solvent Biocompatibility During Biotransformations. Biocatalysis, 2(4), 245-255. doi:10.3109/10242428908992034

    DOI: 10.3109/10242428908992034

    ELECTROMICROBIAL TRANSFORMATIONS USING THE PYRUVATE SYNTHASE SYSTEM OF CLOSTRIDIUM-SPOROGENES (Journal article)

    DIXON, N. M., JAMES, E. W., LOVITT, R. W., & KELL, D. B. (1989). ELECTROMICROBIAL TRANSFORMATIONS USING THE PYRUVATE SYNTHASE SYSTEM OF CLOSTRIDIUM-SPOROGENES. BIOELECTROCHEMISTRY AND BIOENERGETICS, 21(3), 245-259. doi:10.1016/0302-4598(89)85004-4

    DOI: 10.1016/0302-4598(89)85004-4

    Electromicrobial transformations using the pyruvate synthase system of Clostridium sporogenes (Journal article)

    Dixon, N. M., James, E. W., Lovitt, R. W., & Kell, D. B. (1989). Electromicrobial transformations using the pyruvate synthase system of Clostridium sporogenes. Journal of Electroanalytical Chemistry and Interfacial Electrochemistry, 275(3), 245-259. doi:10.1016/0022-0728(89)87226-2

    DOI: 10.1016/0022-0728(89)87226-2

    LOW-FREQUENCY DIELECTRIC-PROPERTIES OF CELL-SUSPENSIONS (Conference Paper)

    DAVEY, C. L., & KELL, D. B. (1989). LOW-FREQUENCY DIELECTRIC-PROPERTIES OF CELL-SUSPENSIONS. In ELECTRIC FIELD PHENOMENA IN BIOLOGICAL SYSTEMS Vol. 21 (pp. 51-62). Retrieved from http://gateway.webofknowledge.com/

    THE CONTROL AND MEASUREMENT OF CO2 DURING FERMENTATIONS (Journal article)

    DIXON, N. M., & KELL, D. B. (1989). THE CONTROL AND MEASUREMENT OF CO2 DURING FERMENTATIONS. JOURNAL OF MICROBIOLOGICAL METHODS, 10(3), 155-176. doi:10.1016/0167-7012(89)90048-1

    DOI: 10.1016/0167-7012(89)90048-1

    THE INHIBITION BY CO2 OF THE GROWTH AND METABOLISM OF MICROORGANISMS (Journal article)

    DIXON, N. M., & KELL, D. B. (1989). THE INHIBITION BY CO2 OF THE GROWTH AND METABOLISM OF MICROORGANISMS. JOURNAL OF APPLIED BACTERIOLOGY, 67(2), 109-136. doi:10.1111/j.1365-2672.1989.tb03387.x

    DOI: 10.1111/j.1365-2672.1989.tb03387.x

    1988

    A RANGE OF CERAMIC BIOSUPPORTS (Journal article)

    ADAMS, J. M., ASH, L. A., BROWN, A. J., JAMES, R., KELL, D. B., SALTER, G. J., & WALTER, R. P. (1988). A RANGE OF CERAMIC BIOSUPPORTS. AMERICAN BIOTECHNOLOGY LABORATORY, 6(7), 34-&. Retrieved from http://gateway.webofknowledge.com/

    MECHANISMS FOR THE INTERACTION BETWEEN NONSTATIONARY ELECTRIC-FIELDS AND BIOLOGICAL-SYSTEMS .2. NONLINEAR DIELECTRIC THEORY AND FREE-ENERGY TRANSDUCTION (Journal article)

    WESTERHOFF, H. V., ASTUMIAN, R. D., & KELL, D. B. (1988). MECHANISMS FOR THE INTERACTION BETWEEN NONSTATIONARY ELECTRIC-FIELDS AND BIOLOGICAL-SYSTEMS .2. NONLINEAR DIELECTRIC THEORY AND FREE-ENERGY TRANSDUCTION. FERROELECTRICS, 86, 79-101. doi:10.1080/00150198808227005

    DOI: 10.1080/00150198808227005

    INDUSTRIAL ACADEMIA (Journal article)

    KELL, D. B. (1988). INDUSTRIAL ACADEMIA. NEW SCIENTIST, 118(1613), 71. Retrieved from http://gateway.webofknowledge.com/

    DIELECTRIC-SPECTROSCOPY OF BIOLOGICAL-SYSTEMS (Journal article)

    KELL, D. B. (1988). DIELECTRIC-SPECTROSCOPY OF BIOLOGICAL-SYSTEMS. ISI ATLAS OF SCIENCE-BIOCHEMISTRY, 1(1), 25-29. Retrieved from http://gateway.webofknowledge.com/

    ELECTROSYNTHESIS AND ELECTROANALYSIS USING CLOSTRIDIUM-SPOROGENES (Journal article)

    JAMES, E. W., KELL, D. B., LOVITT, R. W., & MORRIS, J. G. (1988). ELECTROSYNTHESIS AND ELECTROANALYSIS USING CLOSTRIDIUM-SPOROGENES. BIOELECTROCHEMISTRY AND BIOENERGETICS, 20(1-3), 21-32. doi:10.1016/S0302-4598(98)80002-0

    DOI: 10.1016/S0302-4598(98)80002-0

    Electrosynthesis and electroanalysis using Clostridium sporogenes (Journal article)

    James, E. W., Kell, D. B., Lovitt, R. W., & Gareth Morris, J. (1988). Electrosynthesis and electroanalysis using Clostridium sporogenes. Journal of Electroanalytical Chemistry and Interfacial Electrochemistry, 254(1-3), 21-32. doi:10.1016/0022-0728(80)80331-7

    DOI: 10.1016/0022-0728(80)80331-7

    GROWTH ENERGETICS OF CLOSTRIDIUM-SPOROGENES NCIB 8053 - MODULATION BY CO2 (Journal article)

    DIXON, N. M., LOVITT, R. W., MORRIS, J. G., & KELL, D. B. (1988). GROWTH ENERGETICS OF CLOSTRIDIUM-SPOROGENES NCIB 8053 - MODULATION BY CO2. JOURNAL OF APPLIED BACTERIOLOGY, 65(2), 119-133. doi:10.1111/j.1365-2672.1988.tb01500.x

    DOI: 10.1111/j.1365-2672.1988.tb01500.x

    MECHANISMS FOR THE INTERACTION BETWEEN NONSTATIONARY ELECTRIC-FIELDS AND BIOLOGICAL-SYSTEMS .1. LINEAR DIELECTRIC THEORY AND ITS LIMITATIONS (Journal article)

    KELL, D. B., ASTUMIAN, R. D., & WESTERHOFF, H. V. (1988). MECHANISMS FOR THE INTERACTION BETWEEN NONSTATIONARY ELECTRIC-FIELDS AND BIOLOGICAL-SYSTEMS .1. LINEAR DIELECTRIC THEORY AND ITS LIMITATIONS. FERROELECTRICS, 86, 59-78. doi:10.1080/00150198808227004

    DOI: 10.1080/00150198808227004

    ON THE AUDIO-FREQUENCY AND RADIO-FREQUENCY DIELECTRIC BEHAVIOR OF ANCHORAGE-INDEPENDENT, MOUSE L929-DERIVED LS FIBROBLASTS (Journal article)

    DAVEY, C. L., KELL, D. B., KEMP, R. B., & MEREDITH, R. W. J. (1988). ON THE AUDIO-FREQUENCY AND RADIO-FREQUENCY DIELECTRIC BEHAVIOR OF ANCHORAGE-INDEPENDENT, MOUSE L929-DERIVED LS FIBROBLASTS. BIOELECTROCHEMISTRY AND BIOENERGETICS, 20(1-3), 83-98. doi:10.1016/S0302-4598(98)80007-X

    DOI: 10.1016/S0302-4598(98)80007-X

    On the audio- and radio-frequency dielectric behaviour of anchorage-independent, mouse L929-derived LS fibroblasts (Journal article)

    Davey, C. L., Kell, D. B., Kemp, R. B., & Meredith, R. W. J. (1988). On the audio- and radio-frequency dielectric behaviour of anchorage-independent, mouse L929-derived LS fibroblasts. Journal of Electroanalytical Chemistry and Interfacial Electrochemistry, 254(1-3), 83-98. doi:10.1016/0022-0728(80)80336-6

    DOI: 10.1016/0022-0728(80)80336-6

    THE DYNAMICS OF ELECTROSTATIC INTERACTIONS BETWEEN MEMBRANE-PROTEINS (Journal article)

    WESTERHOFF, H. V., KELL, D. B., & ASTUMIAN, R. D. (1988). THE DYNAMICS OF ELECTROSTATIC INTERACTIONS BETWEEN MEMBRANE-PROTEINS. JOURNAL OF ELECTROSTATICS, 21(2-3), 257-298. doi:10.1016/0304-3886(88)90033-2

    DOI: 10.1016/0304-3886(88)90033-2

    1987

    DETERMINATION OF BIOMASS (Journal article)

    KELL Douglas Bruce., & TODD Robert William. (1987). DETERMINATION OF BIOMASS.

    DETERMINATION OF BIOMASS (Journal article)

    KELL Douglas Bruce. (1987). DETERMINATION OF BIOMASS.

    DETERMINATION OF BIOMASS (Journal article)

    KELL Douglas Bruce. (1987). DETERMINATION OF BIOMASS.

    DETERMINATION OF BIOMASS (Journal article)

    KELL Douglas Bruce. (1987). DETERMINATION OF BIOMASS.

    THE PASSIVE ELECTRICAL-PROPERTIES OF BIOLOGICAL-SYSTEMS - THEIR SIGNIFICANCE IN PHYSIOLOGY, BIOPHYSICS AND BIOTECHNOLOGY (Journal article)

    PETHIG, R., & KELL, D. B. (1987). THE PASSIVE ELECTRICAL-PROPERTIES OF BIOLOGICAL-SYSTEMS - THEIR SIGNIFICANCE IN PHYSIOLOGY, BIOPHYSICS AND BIOTECHNOLOGY. PHYSICS IN MEDICINE AND BIOLOGY, 32(8), 933-970. doi:10.1088/0031-9155/32/8/001

    DOI: 10.1088/0031-9155/32/8/001

    FORCES, FLUXES AND THE CONTROL OF MICROBIAL-GROWTH AND METABOLISM - THE 12TH FLEMING LECTURE (Journal article)

    KELL, D. B. (1987). FORCES, FLUXES AND THE CONTROL OF MICROBIAL-GROWTH AND METABOLISM - THE 12TH FLEMING LECTURE. JOURNAL OF GENERAL MICROBIOLOGY, 133, 1651-1665. Retrieved from http://gateway.webofknowledge.com/

    QUANTUM JUMP (Journal article)

    DEHMELT, H. (1987). QUANTUM JUMP. NATURE, 325(6105), 581. doi:10.1038/325581c0

    DOI: 10.1038/325581c0

    THE ROLES OF OSMOTIC-STRESS AND WATER ACTIVITY IN THE INHIBITION OF THE GROWTH, GLYCOLYSIS AND GLUCOSE PHOSPHOTRANSFERASE SYSTEM OF CLOSTRIDIUM-PASTEURIANUM (Journal article)

    WALTER, R. P., MORRIS, J. G., & KELL, D. B. (1987). THE ROLES OF OSMOTIC-STRESS AND WATER ACTIVITY IN THE INHIBITION OF THE GROWTH, GLYCOLYSIS AND GLUCOSE PHOSPHOTRANSFERASE SYSTEM OF CLOSTRIDIUM-PASTEURIANUM. JOURNAL OF GENERAL MICROBIOLOGY, 133, 259-266. Retrieved from http://gateway.webofknowledge.com/

    DIELECTRIC PERMITTIVITY OF MICROBIAL SUSPENSIONS AT RADIO FREQUENCIES - A NOVEL METHOD FOR THE REAL-TIME ESTIMATION OF MICROBIAL BIOMASS (Journal article)

    HARRIS, C. M., TODD, R. W., BUNGARD, S. J., LOVITT, R. W., MORRIS, J. G., & KELL, D. B. (1987). DIELECTRIC PERMITTIVITY OF MICROBIAL SUSPENSIONS AT RADIO FREQUENCIES - A NOVEL METHOD FOR THE REAL-TIME ESTIMATION OF MICROBIAL BIOMASS. ENZYME AND MICROBIAL TECHNOLOGY, 9(3), 181-186. doi:10.1016/0141-0229(87)90075-5

    DOI: 10.1016/0141-0229(87)90075-5

    EFFECTS OF PCO2 ON THE GROWTH AND METABOLISM OF CLOSTRIDIUM-SPOROGENES NCIB-8053 IN DEFINED MEDIA (Journal article)

    DIXON, N. M., LOVITT, R. W., KELL, D. B., & MORRIS, J. G. (1987). EFFECTS OF PCO2 ON THE GROWTH AND METABOLISM OF CLOSTRIDIUM-SPOROGENES NCIB-8053 IN DEFINED MEDIA. JOURNAL OF APPLIED BACTERIOLOGY, 63(2), 171-182. doi:10.1111/j.1365-2672.1987.tb02700.x

    DOI: 10.1111/j.1365-2672.1987.tb02700.x

    MATRIX-METHOD FOR DETERMINING STEPS MOST RATE-LIMITING TO METABOLIC FLUXES IN BIOTECHNOLOGICAL PROCESSES (Journal article)

    WESTERHOFF, H. V., & KELL, D. B. (1987). MATRIX-METHOD FOR DETERMINING STEPS MOST RATE-LIMITING TO METABOLIC FLUXES IN BIOTECHNOLOGICAL PROCESSES. BIOTECHNOLOGY AND BIOENGINEERING, 30(1), 101-107. doi:10.1002/bit.260300115

    DOI: 10.1002/bit.260300115

    REAL-TIME ESTIMATION OF MICROBIAL BIOMASS DURING FERMENTATIONS, USING A DIELECTRIC PROBE (Journal article)

    KELL, D. B., SAMWORTH, C. M., TODD, R. W., BUNGARD, S. J., & MORRIS, J. G. (1987). REAL-TIME ESTIMATION OF MICROBIAL BIOMASS DURING FERMENTATIONS, USING A DIELECTRIC PROBE. STUDIA BIOPHYSICA, 119(1-3), 153-156. Retrieved from http://gateway.webofknowledge.com/

    THE GROWTH AND NUTRITION OF CLOSTRIDIUM-SPOROGENES NCIB-8053 IN DEFINED MEDIA (Journal article)

    LOVITT, R. W., MORRIS, J. G., & KELL, D. B. (1987). THE GROWTH AND NUTRITION OF CLOSTRIDIUM-SPOROGENES NCIB-8053 IN DEFINED MEDIA. JOURNAL OF APPLIED BACTERIOLOGY, 62(1), 71-80. doi:10.1111/j.1365-2672.1987.tb02382.x

    DOI: 10.1111/j.1365-2672.1987.tb02382.x

    THE PHYSIOLOGY OF CLOSTRIDIUM-SPOROGENES NCIB-8053 GROWING IN DEFINED MEDIA (Journal article)

    LOVITT, R. W., KELL, D. B., & MORRIS, J. G. (1987). THE PHYSIOLOGY OF CLOSTRIDIUM-SPOROGENES NCIB-8053 GROWING IN DEFINED MEDIA. JOURNAL OF APPLIED BACTERIOLOGY, 62(1), 81-92. doi:10.1111/j.1365-2672.1987.tb02383.x

    DOI: 10.1111/j.1365-2672.1987.tb02383.x

    1986

    SOLVENT PRODUCTION BY CLOSTRIDIUM-PASTEURIANUM IN MEDIA OF HIGH SUGAR CONTENT (Journal article)

    HARRIS, J., MULDER, R., KELL, D. B., WALTER, R. P., & MORRIS, J. G. (1986). SOLVENT PRODUCTION BY CLOSTRIDIUM-PASTEURIANUM IN MEDIA OF HIGH SUGAR CONTENT. BIOTECHNOLOGY LETTERS, 8(12), 889-892. doi:10.1007/BF01078654

    DOI: 10.1007/BF01078654

    Metabolic control theory: its role in microbiology and biotechnology (Journal article)

    Kell, D. (1986). Metabolic control theory: its role in microbiology and biotechnology. FEMS Microbiology Letters, 39(4), 305-320. doi:10.1016/0378-1097(86)90020-0

    DOI: 10.1016/0378-1097(86)90020-0

    ON THE LATERAL MOBILITY OF PROTEINS IN PROKARYOTIC MEMBRANES (Journal article)

    KELL, D. B. (1986). ON THE LATERAL MOBILITY OF PROTEINS IN PROKARYOTIC MEMBRANES. BIOCHEMICAL SOCIETY TRANSACTIONS, 14(5), 825-826. doi:10.1042/bst0140825

    DOI: 10.1042/bst0140825

    THE GLUCOSE PHOSPHOTRANSFERASE SYSTEM AS THE MAJOR SITE OF GROWTH-INHIBITION OF CLOSTRIDIUM-PASTEURIANUM IN MEDIA OF HIGH SOLUTE CONTENT (Conference Paper)

    WALTER, R. P., & KELL, D. B. (1986). THE GLUCOSE PHOSPHOTRANSFERASE SYSTEM AS THE MAJOR SITE OF GROWTH-INHIBITION OF CLOSTRIDIUM-PASTEURIANUM IN MEDIA OF HIGH SOLUTE CONTENT. In BIOCHEMICAL SOCIETY TRANSACTIONS Vol. 14 (pp. 882-883). Retrieved from http://gateway.webofknowledge.com/

    Proline reduction by Clostridium sporogenes is coupled to vectorial proton ejection (Journal article)

    Lovitt, R. (1986). Proline reduction by Clostridium sporogenes is coupled to vectorial proton ejection. FEMS Microbiology Letters, 36(2-3), 269-273. doi:10.1016/0378-1097(86)90325-3

    DOI: 10.1016/0378-1097(86)90325-3

    UNCOUPLER TITRATIONS IN CO-RECONSTITUTED SYSTEMS DO NOT DISCRIMINATE BETWEEN LOCALIZED AND DELOCALIZED MECHANISMS OF PHOTOPHOSPHORYLATION (Journal article)

    KELL, D. B. (1986). UNCOUPLER TITRATIONS IN CO-RECONSTITUTED SYSTEMS DO NOT DISCRIMINATE BETWEEN LOCALIZED AND DELOCALIZED MECHANISMS OF PHOTOPHOSPHORYLATION. BIOCHEMICAL JOURNAL, 236(3), 931-932. doi:10.1042/bj2360931

    DOI: 10.1042/bj2360931

    A NOMOGRAPH FOR CALCULATING THE OPTIMAL FREQUENCY FOR DIELECTROPHORESIS AND THE CHARACTERISTIC FREQUENCY OF THE BETA-DISPERSION OF CELL-MEMBRANE VESICLES (Journal article)

    KELL, D. B., & BURNS, A. (1986). A NOMOGRAPH FOR CALCULATING THE OPTIMAL FREQUENCY FOR DIELECTROPHORESIS AND THE CHARACTERISTIC FREQUENCY OF THE BETA-DISPERSION OF CELL-MEMBRANE VESICLES. JOURNAL OF BIOELECTRICITY, 5(1), 139-144. doi:10.3109/15368378609027723

    DOI: 10.3109/15368378609027723

    CONDUCTIMETRIC ASSESSMENT OF THE BIOMASS CONTENT IN SUSPENSIONS OF IMMOBILIZED (GEL-ENTRAPPED) MICROORGANISMS (Journal article)

    LOVITT, R. W., WALTER, R. P., MORRIS, J. G., & KELL, D. B. (1986). CONDUCTIMETRIC ASSESSMENT OF THE BIOMASS CONTENT IN SUSPENSIONS OF IMMOBILIZED (GEL-ENTRAPPED) MICROORGANISMS. APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, 23(3-4), 168-173. Retrieved from http://gateway.webofknowledge.com/

    DIELECTRIC-SPECTROSCOPY OF ENERGY COUPLING MEMBRANES - CHLOROPLAST THYLAKOIDS (Conference Paper)

    SYMONS, M., KORENSTEIN, R., HARRIS, C. M., & KELL, D. B. (1986). DIELECTRIC-SPECTROSCOPY OF ENERGY COUPLING MEMBRANES - CHLOROPLAST THYLAKOIDS. In BIOELECTROCHEMISTRY AND BIOENERGETICS Vol. 16 (pp. 45-54). doi:10.1016/0302-4598(86)80044-7

    DOI: 10.1016/0302-4598(86)80044-7

    DIELECTRIC-SPECTROSCOPY OF PROTEIN TRANSLATIONAL DIFFUSION IN PROKARYOTIC MEMBRANES AND MEMBRANE-VESICLES (Journal article)

    HARRIS, C. M., & KELL, D. B. (1986). DIELECTRIC-SPECTROSCOPY OF PROTEIN TRANSLATIONAL DIFFUSION IN PROKARYOTIC MEMBRANES AND MEMBRANE-VESICLES. BIOELECTROCHEMISTRY AND BIOENERGETICS, 15(2), 183-184. doi:10.1016/0302-4598(86)80026-5

    DOI: 10.1016/0302-4598(86)80026-5

    LOCALIZED PROTONIC COUPLING - OVERVIEW AND CRITICAL-EVALUATION OF TECHNIQUES (Journal article)

    KELL, D. B. (1986). LOCALIZED PROTONIC COUPLING - OVERVIEW AND CRITICAL-EVALUATION OF TECHNIQUES. METHODS IN ENZYMOLOGY, 127, 538-557. Retrieved from http://gateway.webofknowledge.com/

    METABOLIC CONTROL-THEORY - ITS ROLE IN MICROBIOLOGY AND BIOTECHNOLOGY (Journal article)

    KELL, D. B., & WESTERHOFF, H. V. (1986). METABOLIC CONTROL-THEORY - ITS ROLE IN MICROBIOLOGY AND BIOTECHNOLOGY. FEMS MICROBIOLOGY LETTERS, 39(4), 305-320. doi:10.1016/0378-1097(86)90020-0

    DOI: 10.1016/0378-1097(86)90020-0

    PROLINE REDUCTION BY CLOSTRIDIUM-SPOROGENES IS COUPLED TO VECTORIAL PROTON EJECTION (Journal article)

    LOVITT, R. W., KELL, D. B., & MORRIS, J. G. (1986). PROLINE REDUCTION BY CLOSTRIDIUM-SPOROGENES IS COUPLED TO VECTORIAL PROTON EJECTION. FEMS MICROBIOLOGY LETTERS, 36(2-3), 269-273. Retrieved from http://gateway.webofknowledge.com/

    TOWARDS A RATIONAL APPROACH TO THE OPTIMIZATION OF FLUX IN MICROBIAL BIOTRANSFORMATIONS (Journal article)

    KELL, D. B., & WESTERHOFF, H. V. (1986). TOWARDS A RATIONAL APPROACH TO THE OPTIMIZATION OF FLUX IN MICROBIAL BIOTRANSFORMATIONS. TRENDS IN BIOTECHNOLOGY, 4(6), 137-142. doi:10.1016/0167-7799(86)90163-0

    DOI: 10.1016/0167-7799(86)90163-0

    1985

    ON THE DIELECTRICALLY OBSERVABLE CONSEQUENCES OF THE DIFFUSIONAL MOTIONS OF LIPIDS AND PROTEINS IN MEMBRANES .2. EXPERIMENTS WITH MICROBIAL-CELLS, PROTOPLASTS AND MEMBRANE-VESICLES (Journal article)

    HARRIS, C. M., & KELL, D. B. (1985). ON THE DIELECTRICALLY OBSERVABLE CONSEQUENCES OF THE DIFFUSIONAL MOTIONS OF LIPIDS AND PROTEINS IN MEMBRANES .2. EXPERIMENTS WITH MICROBIAL-CELLS, PROTOPLASTS AND MEMBRANE-VESICLES. EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS, 13(1), 11-24. Retrieved from http://gateway.webofknowledge.com/

    ON THE DIELECTRICALLY OBSERVABLE CONSEQUENCES OF THE DIFFUSIONAL MOTIONS OF LIPIDS AND PROTEINS IN MEMBRANES .1. THEORY AND OVERVIEW (Journal article)

    KELL, D. B., & HARRIS, C. M. (1985). ON THE DIELECTRICALLY OBSERVABLE CONSEQUENCES OF THE DIFFUSIONAL MOTIONS OF LIPIDS AND PROTEINS IN MEMBRANES .1. THEORY AND OVERVIEW. EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS, 12(4), 181-197. Retrieved from http://gateway.webofknowledge.com/

    DIELECTRIC-SPECTROSCOPY AND MEMBRANE ORGANIZATION (Journal article)

    KELL, D. B., & HARRIS, C. M. (1985). DIELECTRIC-SPECTROSCOPY AND MEMBRANE ORGANIZATION. JOURNAL OF BIOELECTRICITY, 4(2), 317-348. doi:10.3109/15368378509033261

    DOI: 10.3109/15368378509033261

    INDUSTRIAL SUPPORT (Journal article)

    KELL, D. B. (1985). INDUSTRIAL SUPPORT. NEW SCIENTIST, 108(1476), 68. Retrieved from http://gateway.webofknowledge.com/

    LONG PAPERS (Journal article)

    KELL, D. B. (1985). LONG PAPERS. NEW SCIENTIST, 106(1455), 47. Retrieved from http://gateway.webofknowledge.com/

    THE ESTIMATION OF MICROBIAL BIOMASS (Journal article)

    HARRIS, C. M., & KELL, D. B. (1985). THE ESTIMATION OF MICROBIAL BIOMASS. BIOSENSORS, 1(1), 17-84. doi:10.1016/0265-928X(85)85005-7

    DOI: 10.1016/0265-928X(85)85005-7

    TINOPAL AN AS A SELECTIVE AGENT FOR THE DIFFERENTIATION OF PHYTOPATHOGENIC AND SAPROPHYTIC PSEUDOMONAS SPECIES (Journal article)

    PHILLIPS, M. K., ROBERTS, M. E. R., & KELL, D. B. (1985). TINOPAL AN AS A SELECTIVE AGENT FOR THE DIFFERENTIATION OF PHYTOPATHOGENIC AND SAPROPHYTIC PSEUDOMONAS SPECIES. JOURNAL OF APPLIED BACTERIOLOGY, 58(3), 283-292. doi:10.1111/j.1365-2672.1985.tb01462.x

    DOI: 10.1111/j.1365-2672.1985.tb01462.x

    1984

    A MINIMAL-HYPOTHESIS FOR MEMBRANE-LINKED FREE-ENERGY TRANSDUCTION - THE ROLE OF INDEPENDENT, SMALL COUPLING UNITS (Journal article)

    WESTERHOFF, H. V., MELANDRI, B. A., VENTUROLI, G., AZZONE, G. F., & KELL, D. B. (1984). A MINIMAL-HYPOTHESIS FOR MEMBRANE-LINKED FREE-ENERGY TRANSDUCTION - THE ROLE OF INDEPENDENT, SMALL COUPLING UNITS. BIOCHIMICA ET BIOPHYSICA ACTA, 768(3-4), 257-292. doi:10.1016/0304-4173(84)90019-3

    DOI: 10.1016/0304-4173(84)90019-3

    The antibacterial action of Tinopal AN. (Journal article)

    Phillips, M. K., Kell, D. B., & Rhodes-Roberts, M. E. (1984). The antibacterial action of Tinopal AN.. Journal of general microbiology, 130(8), 1999-2005. doi:10.1099/00221287-130-8-1999

    DOI: 10.1099/00221287-130-8-1999

    ON THE EFFECTS OF THIOCYANATE AND VENTURICIDIN ON RESPIRATION-DRIVEN PROTON TRANSLOCATION IN PARACOCCUS-DENITRIFICANS (Journal article)

    HITCHENS, G. D., & KELL, D. B. (1984). ON THE EFFECTS OF THIOCYANATE AND VENTURICIDIN ON RESPIRATION-DRIVEN PROTON TRANSLOCATION IN PARACOCCUS-DENITRIFICANS. BIOCHIMICA ET BIOPHYSICA ACTA, 766(1), 222-232. doi:10.1016/0005-2728(84)90235-4

    DOI: 10.1016/0005-2728(84)90235-4

    PROTON-TRANSFER PATHWAYS DURING BACTERIAL ELECTRON-TRANSPORT PHOSPHORYLATION (Journal article)

    KELL, D. B., & HITCHENS, G. D. (1984). PROTON-TRANSFER PATHWAYS DURING BACTERIAL ELECTRON-TRANSPORT PHOSPHORYLATION. BIOCHEMICAL SOCIETY TRANSACTIONS, 12(3), 413-414. doi:10.1042/bst0120413

    DOI: 10.1042/bst0120413

    MOSAIC PROTONIC COUPLING HYPOTHESIS FOR FREE-ENERGY TRANSDUCTION (Journal article)

    WESTERHOFF, H. V., MELANDRI, B. A., VENTUROLI, G., AZZONE, G. F., & KELL, D. B. (1984). MOSAIC PROTONIC COUPLING HYPOTHESIS FOR FREE-ENERGY TRANSDUCTION. FEBS LETTERS, 165(1), 1-5. doi:10.1016/0014-5793(84)80002-2

    DOI: 10.1016/0014-5793(84)80002-2

    CONSTRAINTS ON THE LATERAL DIFFUSION OF MEMBRANE-PROTEINS IN PROKARYOTES (Journal article)

    KELL, D. B. (1984). CONSTRAINTS ON THE LATERAL DIFFUSION OF MEMBRANE-PROTEINS IN PROKARYOTES. TRENDS IN BIOCHEMICAL SCIENCES, 9(9), 379. doi:10.1016/0968-0004(84)90217-2

    DOI: 10.1016/0968-0004(84)90217-2

    DIFFUSION OF PROTEIN COMPLEXES IN PROKARYOTIC MEMBRANES - FAST, FREE, RANDOM OR DIRECTED (Journal article)

    KELL, D. B. (1984). DIFFUSION OF PROTEIN COMPLEXES IN PROKARYOTIC MEMBRANES - FAST, FREE, RANDOM OR DIRECTED. TRENDS IN BIOCHEMICAL SCIENCES, 9(3), 86-88. doi:10.1016/0968-0004(84)90097-5

    DOI: 10.1016/0968-0004(84)90097-5

    THE ANTIBACTERIAL ACTION OF TINOPAL AN (Journal article)

    PHILLIPS, M. K., KELL, D. B., & RHODESROBERTS, M. E. (1984). THE ANTIBACTERIAL ACTION OF TINOPAL AN. JOURNAL OF GENERAL MICROBIOLOGY, 130(AUG), 1999-2005. Retrieved from http://gateway.webofknowledge.com/

    1983

    ON THE FUNCTIONAL UNIT OF ENERGY COUPLING IN PHOTOPHOSPHORYLATION BY BACTERIAL CHROMATOPHORES (Journal article)

    HITCHENS, G. D., & KELL, D. B. (1983). ON THE FUNCTIONAL UNIT OF ENERGY COUPLING IN PHOTOPHOSPHORYLATION BY BACTERIAL CHROMATOPHORES. BIOCHIMICA ET BIOPHYSICA ACTA, 723(2), 308-316. doi:10.1016/0005-2728(83)90130-5

    DOI: 10.1016/0005-2728(83)90130-5

    UNCOUPLERS CAN SHUTTLE BETWEEN LOCALIZED ENERGY-COUPLING SITES DURING PHOTOPHOSPHORYLATION BY CHROMATOPHORES OF RHODOPSEUDOMONAS-CAPSULATA N22 (Journal article)

    HITCHENS, G. D., & KELL, D. B. (1983). UNCOUPLERS CAN SHUTTLE BETWEEN LOCALIZED ENERGY-COUPLING SITES DURING PHOTOPHOSPHORYLATION BY CHROMATOPHORES OF RHODOPSEUDOMONAS-CAPSULATA N22. BIOCHEMICAL JOURNAL, 212(1), 25-30. doi:10.1042/bj2120025

    DOI: 10.1042/bj2120025

    NON-LINEAR SYSTEMS - COHERENT EXCITATION IN BIOLOGY (Journal article)

    KEILMANN, F., & KELL, D. B. (1983). NON-LINEAR SYSTEMS - COHERENT EXCITATION IN BIOLOGY. NATURE, 301(5902), 656-657. doi:10.1038/301656b0

    DOI: 10.1038/301656b0

    COUPLING FACTOR-B AND THE BOVINE MITOCHONDRIAL H+-ATP SYNTHASE (Journal article)

    KELL, D. (1983). COUPLING FACTOR-B AND THE BOVINE MITOCHONDRIAL H+-ATP SYNTHASE. TRENDS IN BIOCHEMICAL SCIENCES, 8(5), 153-154. doi:10.1016/0968-0004(83)90158-5

    DOI: 10.1016/0968-0004(83)90158-5

    DIELECTRIC-PROPERTIES OF BACTERIAL CHROMATOPHORES (Conference Paper)

    KELL, D. B. (1983). DIELECTRIC-PROPERTIES OF BACTERIAL CHROMATOPHORES. In BIOELECTROCHEMISTRY AND BIOENERGETICS Vol. 11 (pp. 405-415). doi:10.1016/0302-4598(83)90037-5

    DOI: 10.1016/0302-4598(83)90037-5

    Dielectric properties of bacterial chromatophores (Journal article)

    Kell, D. B. (1983). Dielectric properties of bacterial chromatophores. Journal of Electroanalytical Chemistry and Interfacial Electrochemistry, 156, 405-415. doi:10.1016/s0022-0728(83)80692-5

    DOI: 10.1016/s0022-0728(83)80692-5

    QUANTUM JUMP (Journal article)

    KELL, D. B. (1983). QUANTUM JUMP. NEW SCIENTIST, 98(1352), 41. Retrieved from http://gateway.webofknowledge.com/

    THE RADIO-FREQUENCY DIELECTRIC-PROPERTIES OF YEAST-CELLS MEASURED WITH A RAPID, AUTOMATED, FREQUENCY-DOMAIN DIELECTRIC SPECTROMETER (Journal article)

    HARRIS, C. M., & KELL, D. B. (1983). THE RADIO-FREQUENCY DIELECTRIC-PROPERTIES OF YEAST-CELLS MEASURED WITH A RAPID, AUTOMATED, FREQUENCY-DOMAIN DIELECTRIC SPECTROMETER. BIOELECTROCHEMISTRY AND BIOENERGETICS, 11(1), 15-28. doi:10.1016/0302-4598(83)85097-1

    DOI: 10.1016/0302-4598(83)85097-1

    The radio-frequency dielectric properties of yeast cells measured with a rapid, automated, frequency-domain dielectric spectrometer (Journal article)

    Harris, C. M., & Kell, D. B. (1983). The radio-frequency dielectric properties of yeast cells measured with a rapid, automated, frequency-domain dielectric spectrometer. Journal of Electroanalytical Chemistry and Interfacial Electrochemistry, 156, 15-28. doi:10.1016/s0022-0728(83)80648-2

    DOI: 10.1016/s0022-0728(83)80648-2

    1982

    General discussion (Journal article)

    Krishtalik, L. I., Williams, R. J. P., van Lith, D., Larsson, S., Moore, G. R., Sutin, N., . . . Kell, D. B. (n.d.). General discussion. Faraday Discuss. Chem. Soc., 74(0), 389-405. doi:10.1039/dc9827400389

    DOI: 10.1039/dc9827400389

    PROTON-COUPLED ENERGY TRANSDUCTION BY BIOLOGICAL-MEMBRANES - PRINCIPLES, PATHWAYS AND PRAXIS (Journal article)

    KELL, D. B., & HITCHENS, G. D. (1982). PROTON-COUPLED ENERGY TRANSDUCTION BY BIOLOGICAL-MEMBRANES - PRINCIPLES, PATHWAYS AND PRAXIS. FARADAY DISCUSSIONS, 74, 377-388. doi:10.1039/dc9827400377

    DOI: 10.1039/dc9827400377

    LOCALIZED ENERGY COUPLING DURING PHOTOPHOSPHORYLATION BY CHROMATOPHORES OF RHODOPSEUDOMONAS-CAPSULATA N22 (Journal article)

    HITCHENS, G. D., & KELL, D. B. (1982). LOCALIZED ENERGY COUPLING DURING PHOTOPHOSPHORYLATION BY CHROMATOPHORES OF RHODOPSEUDOMONAS-CAPSULATA N22. BIOSCIENCE REPORTS, 2(10), 743-749. doi:10.1007/BF01114933

    DOI: 10.1007/BF01114933

    Transmembrane respiration-driven H+ translocation is unimpaired in an eup mutant of Escherichia coli. (Journal article)

    Hitchens, G. D., Kell, D. B., & Morris, J. G. (1982). Transmembrane respiration-driven H+ translocation is unimpaired in an eup mutant of Escherichia coli.. Journal of general microbiology, 128(9), 2207-2209. doi:10.1099/00221287-128-9-2207

    DOI: 10.1099/00221287-128-9-2207

    ON THE EXTENT OF LOCALIZATION OF THE ENERGIZED MEMBRANE STATE IN CHROMATOPHORES FROM RHODOPSEUDOMONAS-CAPSULATA N22 (Journal article)

    HITCHENS, G. D., & KELL, D. B. (1982). ON THE EXTENT OF LOCALIZATION OF THE ENERGIZED MEMBRANE STATE IN CHROMATOPHORES FROM RHODOPSEUDOMONAS-CAPSULATA N22. BIOCHEMICAL JOURNAL, 206(2), 351-357. doi:10.1042/bj2060351

    DOI: 10.1042/bj2060351

    A NOVEL INHIBITOR OF NADH DEHYDROGENASE IN PARACOCCUS-DENITRIFICANS (Journal article)

    PHILLIPS, M. K., & KELL, D. B. (1982). A NOVEL INHIBITOR OF NADH DEHYDROGENASE IN PARACOCCUS-DENITRIFICANS. FEBS LETTERS, 140(2), 248-250. doi:10.1016/0014-5793(82)80905-8

    DOI: 10.1016/0014-5793(82)80905-8

    BUTYRICIN 7423 AND THE MEMBRANE H+-ATPASE OF CLOSTRIDIUM-PASTEURIANUM (Journal article)

    CLARKE, D. J., KELL, D. B., MORLEY, C. D., & MORRIS, J. G. (1982). BUTYRICIN 7423 AND THE MEMBRANE H+-ATPASE OF CLOSTRIDIUM-PASTEURIANUM. ARCHIVES OF MICROBIOLOGY, 131(1), 81-86. doi:10.1007/BF00451503

    DOI: 10.1007/BF00451503

    A rose by any other name (Journal article)

    Kell, D. (1982). A rose by any other name. Trends in Biochemical Sciences, 7(12), 420. doi:10.1016/s0968-0004(82)80002-9

    DOI: 10.1016/s0968-0004(82)80002-9

    BACTERIA THAT ARE RESISTANT TO UNCOUPLERS - WHAT CAN THEY TELL US (Journal article)

    KELL, D. B. (1982). BACTERIA THAT ARE RESISTANT TO UNCOUPLERS - WHAT CAN THEY TELL US. TRENDS IN BIOCHEMICAL SCIENCES, 7(1), 1-2. doi:10.1016/0968-0004(82)90049-4

    DOI: 10.1016/0968-0004(82)90049-4

    ENZYMES AS ENERGY FUNNELS (Journal article)

    KELL, D. B. (1982). ENZYMES AS ENERGY FUNNELS. TRENDS IN BIOCHEMICAL SCIENCES, 7(10), 349. doi:10.1016/0968-0004(82)90104-9

    DOI: 10.1016/0968-0004(82)90104-9

    ON THE MODE OF ACTION OF THE BACTERIOCIN BUTYRICIN-7423 - EFFECTS ON MEMBRANE-POTENTIAL AND POTASSIUM-ION ACCUMULATION IN CLOSTRIDIUM-PASTEURIANUM (Journal article)

    CLARKE, D. J., MORLEY, C. D., KELL, D. B., & MORRIS, J. G. (1982). ON THE MODE OF ACTION OF THE BACTERIOCIN BUTYRICIN-7423 - EFFECTS ON MEMBRANE-POTENTIAL AND POTASSIUM-ION ACCUMULATION IN CLOSTRIDIUM-PASTEURIANUM. EUROPEAN JOURNAL OF BIOCHEMISTRY, 127(1), 105-116. doi:10.1111/j.1432-1033.1982.tb06843.x

    DOI: 10.1111/j.1432-1033.1982.tb06843.x

    ROLE OF ION-SELECTIVE ELECTRODES IN MICROBIAL PROCESS CONTROL. (Conference Paper)

    Clarke, D. J., Kell, D. B., Morris, J. G., & Burns, A. (1982). ROLE OF ION-SELECTIVE ELECTRODES IN MICROBIAL PROCESS CONTROL.. In Ion-selective electrode reviews Vol. 4 (pp. 75-131).

    TRANSMEMBRANE RESPIRATION-DRIVEN H+ TRANSLOCATION IS UNIMPAIRED IN AN EUP MUTANT OF ESCHERICHIA-COLI (Journal article)

    HITCHENS, G. D., KELL, D. B., & MORRIS, J. G. (1982). TRANSMEMBRANE RESPIRATION-DRIVEN H+ TRANSLOCATION IS UNIMPAIRED IN AN EUP MUTANT OF ESCHERICHIA-COLI. JOURNAL OF GENERAL MICROBIOLOGY, 128(SEP), 2207-2209. Retrieved from http://gateway.webofknowledge.com/

    1981

    Quantitative Problems in Biochemistry (Sixth Edition) (Journal article)

    Kell, D. (1981). Quantitative Problems in Biochemistry (Sixth Edition). FEBS Letters, 136(1), 181. doi:10.1016/0014-5793(81)81241-0

    DOI: 10.1016/0014-5793(81)81241-0

    A benzoxazole inhibitor of NADH dehydrogenase in Paracoccus denitrificans (Journal article)

    Phillips, M. (1981). A benzoxazole inhibitor of NADH dehydrogenase in Paracoccus denitrificans. FEMS Microbiology Letters, 11(2-3), 111-113. doi:10.1016/0378-1097(81)90091-4

    DOI: 10.1016/0378-1097(81)90091-4

    POLAROGRAPHIC INVESTIGATION OF SOME CYTOKININS (Journal article)

    SMYTH, M. R., & KELL, D. B. (1981). POLAROGRAPHIC INVESTIGATION OF SOME CYTOKININS. JOURNAL OF ELECTROANALYTICAL CHEMISTRY, 122(MAY), 363-365. doi:10.1016/S0022-0728(81)80168-4

    DOI: 10.1016/S0022-0728(81)80168-4

    Polarographic investigation of some cytokinins (Journal article)

    Smyth, M. (1981). Polarographic investigation of some cytokinins. Journal of Electroanalytical Chemistry, 122(1), 363-365. doi:10.1016/0368-1874(81)87369-8

    DOI: 10.1016/0368-1874(81)87369-8

    ESTIMATION WITH AN ION-SELECTIVE ELECTRODE OF THE MEMBRANE-POTENTIAL IN CELLS OF PARACOCCUS-DENITRIFICANS FROM THE UPTAKE OF THE BUTYLTRIPHENYLPHOSPHONIUM CATION DURING AEROBIC AND ANAEROBIC RESPIRATION (Journal article)

    MCCARTHY, J. E. G., FERGUSON, S. J., & KELL, D. B. (1981). ESTIMATION WITH AN ION-SELECTIVE ELECTRODE OF THE MEMBRANE-POTENTIAL IN CELLS OF PARACOCCUS-DENITRIFICANS FROM THE UPTAKE OF THE BUTYLTRIPHENYLPHOSPHONIUM CATION DURING AEROBIC AND ANAEROBIC RESPIRATION. BIOCHEMICAL JOURNAL, 196(1), 311-321. doi:10.1042/bj1960311

    DOI: 10.1042/bj1960311

    ON THE PERMEABILITY TO WEAK ACIDS AND BASES OF THE CYTOPLASMIC MEMBRANE OF CLOSTRIDIUM-PASTEURIANUM (Journal article)

    KELL, D. B., PECK, M. W., RODGER, G., & MORRIS, J. G. (1981). ON THE PERMEABILITY TO WEAK ACIDS AND BASES OF THE CYTOPLASMIC MEMBRANE OF CLOSTRIDIUM-PASTEURIANUM. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 99(1), 81-88. doi:10.1016/0006-291X(81)91715-0

    DOI: 10.1016/0006-291X(81)91715-0

    A BENZOXAZOLE INHIBITOR OF NADH DEHYDROGENASE IN PARACOCCUS-DENITRIFICANS (Journal article)

    PHILLIPS, M. K., & KELL, D. B. (1981). A BENZOXAZOLE INHIBITOR OF NADH DEHYDROGENASE IN PARACOCCUS-DENITRIFICANS. FEMS MICROBIOLOGY LETTERS, 11(2-3), 111-113. Retrieved from http://gateway.webofknowledge.com/

    ARE LIPOSOMES GOOD MODELS FOR BIOMEMBRANES (Journal article)

    KELL, D. B. (1981). ARE LIPOSOMES GOOD MODELS FOR BIOMEMBRANES. TRENDS IN BIOCHEMICAL SCIENCES, 6(11), R8-R9. Retrieved from http://gateway.webofknowledge.com/

    ON PROTON-COUPLED INFORMATION-TRANSFER ALONG THE SURFACE OF BIOLOGICAL-MEMBRANES AND THE MODE OF ACTION OF CERTAIN COLICINS (Journal article)

    KELL, D. B., CLARKE, D. J., & MORRIS, J. G. (1981). ON PROTON-COUPLED INFORMATION-TRANSFER ALONG THE SURFACE OF BIOLOGICAL-MEMBRANES AND THE MODE OF ACTION OF CERTAIN COLICINS. FEMS MICROBIOLOGY LETTERS, 11(1), 1-11. Retrieved from http://gateway.webofknowledge.com/

    ON THE ROLE OF INTERFACIAL WATER IN PROTON-MOTIVE SYSTEMS (Conference Paper)

    KELL, D. B. (1981). ON THE ROLE OF INTERFACIAL WATER IN PROTON-MOTIVE SYSTEMS. In HOPPE-SEYLERS ZEITSCHRIFT FUR PHYSIOLOGISCHE CHEMIE Vol. 362 (pp. 1186). Retrieved from http://gateway.webofknowledge.com/

    On proton-coupled information transfer along the surface of biological membranes and the mode of action of certain colicins (Journal article)

    Kell, D. (1981). On proton-coupled information transfer along the surface of biological membranes and the mode of action of certain colicins. FEMS Microbiology Letters, 11(1), 1-11. doi:10.1016/0378-1097(81)90046-x

    DOI: 10.1016/0378-1097(81)90046-x

    POLAROGRAPHIC ASSAY OF THE BINDING OF CERTAIN PROBE MOLECULES TO ILLUMINATED BACTERIORHODOPSIN SHEETS (Journal article)

    KELL, D. B., & GRIFFITHS, A. M. (1981). POLAROGRAPHIC ASSAY OF THE BINDING OF CERTAIN PROBE MOLECULES TO ILLUMINATED BACTERIORHODOPSIN SHEETS. PHOTOBIOCHEMISTRY AND PHOTOBIOPHYSICS, 2(1-2), 105-110. Retrieved from http://gateway.webofknowledge.com/

    PROTEINACEOUS PROTON PUMPS - A MINIMAL MODEL, SOME PROPERTIES, AND THEIR POSSIBLE UNIVERSALITY (Journal article)

    KELL, D. B., BURNS, A., CLARKE, D. J., & MORRIS, J. G. (1981). PROTEINACEOUS PROTON PUMPS - A MINIMAL MODEL, SOME PROPERTIES, AND THEIR POSSIBLE UNIVERSALITY. SPECULATIONS IN SCIENCE AND TECHNOLOGY, 4(2), 109-120. Retrieved from http://gateway.webofknowledge.com/

    PROTON CONDUCTION AND CHEMI-OSMOSIS (Journal article)

    KELL, D. B. (1981). PROTON CONDUCTION AND CHEMI-OSMOSIS. CHEMISTRY IN BRITAIN, 17(4), 165-166. Retrieved from http://gateway.webofknowledge.com/

    THE ELECTRON-TRANSPORT SYSTEM AND HYDROGENASE OF PARACOCCUS-DENITRIFICANS (Journal article)

    VIGNAIS, P. M., HENRY, M. F., SIM, E., & KELL, D. B. (1981). THE ELECTRON-TRANSPORT SYSTEM AND HYDROGENASE OF PARACOCCUS-DENITRIFICANS. CURRENT TOPICS IN BIOENERGETICS, 12, 115-196. Retrieved from http://gateway.webofknowledge.com/

    1980

    AN ADENINE-NUCLEOTIDE TRANSLOCASE IN THE PROCARYOTE METHANOBACTERIUM-THERMOAUTOTROPHICUM (Journal article)

    DODDEMA, H. J., CLAESEN, C. A., KELL, D. B., VANDERDRIFT, C., & VOGELS, G. D. (1980). AN ADENINE-NUCLEOTIDE TRANSLOCASE IN THE PROCARYOTE METHANOBACTERIUM-THERMOAUTOTROPHICUM. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 95(3), 1288-1293. doi:10.1016/0006-291X(80)91613-7

    DOI: 10.1016/0006-291X(80)91613-7

    FORMULATION AND SOME BIOLOGICAL USES OF A BUFFER MIXTURE WHOSE BUFFERING CAPACITY IS RELATIVELY INDEPENDENT OF PH IN THE RANGE PH 4-9 (Journal article)

    KELL, D. B., & MORRIS, J. G. (1980). FORMULATION AND SOME BIOLOGICAL USES OF A BUFFER MIXTURE WHOSE BUFFERING CAPACITY IS RELATIVELY INDEPENDENT OF PH IN THE RANGE PH 4-9. JOURNAL OF BIOCHEMICAL AND BIOPHYSICAL METHODS, 3(3), 143-150. doi:10.1016/0165-022X(80)90013-5

    DOI: 10.1016/0165-022X(80)90013-5

    ROLE OF ION-SELECTIVE ELECTRODES IN IMPROVING FERMENTATION YIELDS (Journal article)

    KELL, D. B. (1980). ROLE OF ION-SELECTIVE ELECTRODES IN IMPROVING FERMENTATION YIELDS. PROCESS BIOCHEMISTRY, 15(1), 18-+. Retrieved from http://gateway.webofknowledge.com/

    1979

    OXIDATION-REDUCTION PROPERTIES OF COENZYME-M (2-MERCAPTOETHANE SULFONATE) AT THE MERCURY-ELECTRODE (Journal article)

    KELL, D. B., & MORRIS, J. G. (1979). OXIDATION-REDUCTION PROPERTIES OF COENZYME-M (2-MERCAPTOETHANE SULFONATE) AT THE MERCURY-ELECTRODE. FEBS LETTERS, 108(2), 481-484. doi:10.1016/0014-5793(79)80593-1

    DOI: 10.1016/0014-5793(79)80593-1

    Physical Aspects of Protein Interactions (Journal article)

    Kell, D. (1979). Physical Aspects of Protein Interactions. FEBS Letters, 107(2), 442. doi:10.1016/0014-5793(79)80427-5

    DOI: 10.1016/0014-5793(79)80427-5

    Comparative aspects of the energetics of oxidative phosphorylation in bacteria and mitochondria. (Journal article)

    Ferguson, S. J., Sorgato, M. C., Kell, D. B., & John, P. (1979). Comparative aspects of the energetics of oxidative phosphorylation in bacteria and mitochondria.. Biochemical Society transactions, 7(5), 870-874. doi:10.1042/bst0070870

    DOI: 10.1042/bst0070870

    The generation of a membrane potential by a fermentative bacterium [proceedings]. (Journal article)

    Clarke, D. J., Kell, D. B., & Morris, J. G. (1979). The generation of a membrane potential by a fermentative bacterium [proceedings].. Biochemical Society transactions, 7(5), 1111-1112. doi:10.1042/bst0071111

    DOI: 10.1042/bst0071111

    FUNCTIONAL PROTON CURRENT PATHWAY OF ELECTRON-TRANSPORT PHOSPHORYLATION - ELECTRODIC VIEW (Journal article)

    KELL, D. B. (1979). FUNCTIONAL PROTON CURRENT PATHWAY OF ELECTRON-TRANSPORT PHOSPHORYLATION - ELECTRODIC VIEW. BIOCHIMICA ET BIOPHYSICA ACTA, 549(1), 55-99. doi:10.1016/0304-4173(79)90018-1

    DOI: 10.1016/0304-4173(79)90018-1

    COMPARISON OF PERMEANT ION UPTAKE AND CAROTENOID BAND SHIFT AS METHODS FOR DETERMINING THE MEMBRANE-POTENTIAL IN CHROMATOPHORES FROM RHODOPSEUDOMONAS-SPHAEROIDES GA (Journal article)

    FERGUSON, S. J., JONES, O. T. G., KELL, D. B., & SORGATO, M. C. (1979). COMPARISON OF PERMEANT ION UPTAKE AND CAROTENOID BAND SHIFT AS METHODS FOR DETERMINING THE MEMBRANE-POTENTIAL IN CHROMATOPHORES FROM RHODOPSEUDOMONAS-SPHAEROIDES GA. BIOCHEMICAL JOURNAL, 180(1), 75-85. doi:10.1042/bj1800075

    DOI: 10.1042/bj1800075

    Evidence from P-31 Nuclear Magnetic Resonance that Polyphosphate Synthesis is a Slip Reaction in Paracoccus denitrificans (Journal article)

    Ferguson, S. J., Gadian, D. G., & Kell, D. B. (1979). Evidence from P-31 Nuclear Magnetic Resonance that Polyphosphate Synthesis is a Slip Reaction in Paracoccus denitrificans. BIOCHEMICAL SOCIETY TRANSACTIONS, 7, 176-179. doi:10.1042/bst0070176

    DOI: 10.1042/bst0070176

    1978

    On the Current-Voltage Relationships of Energy-Transducing Membranes: Phosphorylating Membrane Vesicles from Paracoccus denitrificans (Journal article)

    Kell, D. B., John, P., & Ferguson, S. J. (1978). On the Current-Voltage Relationships of Energy-Transducing Membranes: Phosphorylating Membrane Vesicles from Paracoccus denitrificans. BIOCHEMICAL SOCIETY TRANSACTIONS, 6, 1292-1295. doi:10.1042/bst0061292

    DOI: 10.1042/bst0061292

    On the Current-Voltage Relationships of Energy-Transducing Membranes: Submitochondrial Particles (Journal article)

    Sorgato, M. C., Ferguson, S. J., & Kell, D. B. (1978). On the Current-Voltage Relationships of Energy-Transducing Membranes: Submitochondrial Particles. BIOCHEMICAL SOCIETY TRANSACTIONS, 6, 1301-1302. doi:10.1042/bst0061301

    DOI: 10.1042/bst0061301

    PROTONMOTIVE FORCE IN BOVINE HEART SUB-MITOCHONDRIAL PARTICLES - MAGNITUDE, SITES OF GENERATION AND COMPARISON WITH PHOSPHORYLATION POTENTIAL (Journal article)

    SORGATO, M. C., FERGUSON, S. J., KELL, D. B., & JOHN, P. (1978). PROTONMOTIVE FORCE IN BOVINE HEART SUB-MITOCHONDRIAL PARTICLES - MAGNITUDE, SITES OF GENERATION AND COMPARISON WITH PHOSPHORYLATION POTENTIAL. BIOCHEMICAL JOURNAL, 174(1), 237-256. doi:10.1042/bj1740237

    DOI: 10.1042/bj1740237

    PROTONMOTIVE FORCE IN PHOSPHORYLATING MEMBRANE-VESICLES FROM PARACOCCUS-DENITRIFICANS - MAGNITUDE, SITES OF GENERATION AND COMPARISON WITH PHOSPHORYLATION POTENTIAL (Journal article)

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    MEASUREMENT BY A FLOW DIALYSIS TECHNIQUE OF STEADY-STATE PROTON-MOTIVE FORCE IN CHROMATOPHORES FROM RHODOSPIRILLUM-RUBRUM - COMPARISON WITH PHOSPHORYLATION POTENTIAL (Journal article)

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    Resolution of Paracoccus denitrificans membrane vesicles of differing configuration using affinity chromatography (Journal article)

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    CONTINUOUS MONITORING OF ELECTRICAL POTENTIAL ACROSS ENERGY-TRANSDUCING MEMBRANES USING ION-SELECTIVE ELECTRODES - APPLICATION TO SUB-MITOCHONDRIAL PARTICLES AND CHROMATOPHORES (Journal article)

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    RESOLUTION OF PARACOCCUS-DENITRIFICANS MEMBRANE-VESICLES OF DIFFERING CONFIGURATION USING AFFINITY CHROMATOGRAPHY (Journal article)

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    1976

    BCG inhibition of murine leudemia: local suppression and systemic tumor immunity require different doses. (Journal article)

    Bartlett, G. L., Purnell, D. M., & Kreider, J. W. (1976). BCG inhibition of murine leudemia: local suppression and systemic tumor immunity require different doses.. Science (New York, N.Y.), 191(4224), 299-301. doi:10.1126/science.1108198

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