2024
Hall, A., Middlehurst, B., Cadogan, M. A. M., Reed, X., Billingsley, K. J., Bubb, V. J., & Quinn, J. P. (2024). A SINE-VNTR-Alu at the LRIG2 locus is associated with proximal and distal gene expression in CRISPR and population models.. Scientific reports, 14(1), 792. doi:10.1038/s41598-023-50307-wDOI: 10.1038/s41598-023-50307-w
2023
Deciphering the role of a SINE-VNTR-Alu retrotransposon polymorphism as a biomarker of Parkinson’s disease progression (Preprint)
DOI: 10.21203/rs.3.rs-2667832/v1
Fröhlich, A., Hughes, L. S., Middlehurst, B., Pfaff, A. L., Bubb, V. J., Koks, S., & Quinn, J. P. (2023). CRISPR deletion of a SINE-VNTR-<i>Alu</i> (SVA_67) retrotransposon demonstrates its ability to differentially modulate gene expression at the <i>MAPT</i> locus.. Frontiers in neurology, 14, 1273036. doi:10.3389/fneur.2023.1273036DOI: 10.3389/fneur.2023.1273036
2022
Marshall, J. N. G., Fröhlich, A., Li, L., Pfaff, A. L., Middlehurst, B., Spargo, T. P., . . . Quinn, J. P. (2022). A polymorphic transcriptional regulatory domain in the amyotrophic lateral sclerosis risk gene <i>CFAP410</i> correlates with differential isoform expression.. Frontiers in molecular neuroscience, 15, 954928. doi:10.3389/fnmol.2022.954928DOI: 10.3389/fnmol.2022.954928
2021
Wilm, T. P., Tanton, H., Mutter, F., Foisor, V., Middlehurst, B., Ward, K., . . . Wilm, B. (2021). Restricted differentiative capacity of Wt1-expressing peritoneal mesothelium in postnatal and adult mice. SCIENTIFIC REPORTS, 11(1). doi:10.1038/s41598-021-95380-1DOI: 10.1038/s41598-021-95380-1
Middlehurst, B. (2021, June 16). The role of endogenous retrotransposable elements in Parkinson’s disease..
2020
Rose, C., Casas-Sanchez, A., Dyer, N. A., Solorzano, C., Beckett, A. J., Middlehurst, B., . . . Acosta-Serrano, A. (2020). Trypanosoma brucei colonizes the tsetse gut via an immature peritrophic matrix in the proventriculus. Nature Microbiology, 5(7), 909-916. doi:10.1038/s41564-020-0707-zDOI: 10.1038/s41564-020-0707-z
2019
Billingsley, K. J., Barbosa, I. A., Bandres-Ciga, S., Quinn, J. P., Bubb, V. J., Deshpande, C., . . . IPDGC. (2019). Mitochondria function associated genes contribute to Parkinson's Disease risk and later age at onset. NPJ PARKINSONS DISEASE, 5. doi:10.1038/s41531-019-0080-xDOI: 10.1038/s41531-019-0080-x
Quinn, J. P., Billingsley, K., Reynolds, R. H., Botia, J., Nalls, M. A., Hardy, J., . . . Ryten, M. (2019). Moving beyond neurons: the role of cell type-specific gene regulation in Parkinson’s disease heritability. npj Parkinson's Disease, 5. doi:10.1038/s41531-019-0076-6DOI: 10.1038/s41531-019-0076-6
2015
The role of Ca2+influx in endocytic vacuole formation in pancreatic acinar cells (Journal article)
Voronina, S., Collier, D., Chvanov, M., Middlehurst, B., Beckett, A., Prior, I., . . . Tepikin, A. V. (2015). The role of Ca2+influx in endocytic vacuole formation in pancreatic acinar cells. Biochemical Journal, 465(3), 405-412. doi:10.1042/BJ20140398DOI: 10.1042/BJ20140398
