Research outputs
2024
Identification of heparin-binding amino acid residues in antibody HS4C3 with the potential to design antibodies against heparan sulfate domains
Damen, L. A. A., Bui, T. P., van Wessel, T., Li, Y., Straten, B. F., Pampiermole, R., . . . van Kuppevelt, T. H. (2024). Identification of heparin-binding amino acid residues in antibody HS4C3 with the potential to design antibodies against heparan sulfate domains. GLYCOBIOLOGY, 34(8). doi:10.1093/glycob/cwae046
2020
Glycosaminoglycans induce conformational change in the SARS-CoV-2 Spike S1 Receptor Binding Domain
Mycroft-West, C., Su, D., Li, Y., Guimond, S., Rudd, T., Elli, S., . . . Skidmore, M. (2020). Glycosaminoglycans induce conformational change in the SARS-CoV-2 Spike S1 Receptor Binding Domain. doi:10.1101/2020.04.29.068767
SARS-CoV-2 Spike S1 Receptor Binding Domain undergoes Conformational Change upon Interaction with Low Molecular Weight Heparins
Mycroft-West, C., Su, D., Li, Y., Guimond, S., Rudd, T., Elli, S., . . . Skidmore, M. (2020). SARS-CoV-2 Spike S1 Receptor Binding Domain undergoes Conformational Change upon Interaction with Low Molecular Weight Heparins. doi:10.1101/2020.04.29.068486
Heparin inhibits cellular invasion by SARS-CoV-2: structural dependence of the interaction of the surface protein (spike) S1 receptor binding domain with heparin
Mycroft-West, C., Su, D., Pagani, I., Rudd, T., Elli, S., Guimond, S., . . . Skidmore, M. (2020). Heparin inhibits cellular invasion by SARS-CoV-2: structural dependence of the interaction of the surface protein (spike) S1 receptor binding domain with heparin. doi:10.1101/2020.04.28.066761
The 2019 coronavirus (SARS-CoV-2) surface protein (Spike) S1 Receptor Binding Domain undergoes conformational change upon heparin binding
Mycroft-West, C., Su, D., Elli, S., Li, Y., Guimond, S., Miller, G., . . . Skidmore, M. (2020). The 2019 coronavirus (SARS-CoV-2) surface protein (Spike) S1 Receptor Binding Domain undergoes conformational change upon heparin binding. doi:10.1101/2020.02.29.971093
2019
Selective labelling of arginine residues engaged in binding sulfatedglycosaminoglycans
Bui, T., Li, Y., Nunes, Q., Wilkinson, M., & Fernig, D. (2019). Selective labelling of arginine residues engaged in binding sulfatedglycosaminoglycans. doi:10.1101/574947
2018
The heparin-binding proteome in normal pancreas and murine experimental acute pancreatitis
Nunes, Q., Su, D., Brownridge, P., Simpson, D., Sun, C., Li, Y., . . . Fernig, D. (2018). The heparin-binding proteome in normal pancreas and murine experimental acute pancreatitis. doi:10.1101/497271
New tools for carbohydrate sulfation analysis: heparan sulfate 2-O-sulfotransferase (HS2ST) is a target for small-molecule protein kinase inhibitors
Byrne, D. P., Li, Y., Ramakrishnan, K., Barsukov, I. L., Yates, E. A., Eyers, C. E., . . . Eyers, P. A. (2018). New tools for carbohydrate sulfation analysis: heparan sulfate 2-O-sulfotransferase (HS2ST) is a target for small-molecule protein kinase inhibitors. BIOCHEMICAL JOURNAL, 475(15), 2417-2433. doi:10.1042/BCJ20180265
New tools for evaluating protein tyrosine sulfation: tyrosylprotein sulfotransferases (TPSTs) are novel targets for RAF protein kinase inhibitors
Byrne, D. P., Li, Y., Ngamlert, P., Ramakrishnan, K., Eyers, C. E., Wells, C., . . . Eyers, P. A. (2018). New tools for evaluating protein tyrosine sulfation: tyrosylprotein sulfotransferases (TPSTs) are novel targets for RAF protein kinase inhibitors. BIOCHEMICAL JOURNAL, 475(15), 2435-2455. doi:10.1042/BCJ20180266
Fibroblast growth factor 9 subfamily and the heart
Wang, S., Li, Y., Jiang, C., & Tian, H. (2018). Fibroblast growth factor 9 subfamily and the heart. APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, 102(2), 605-613. doi:10.1007/s00253-017-8652-3
2016
Heparin binding preference and structures in the fibroblast growth factor family parallel their evolutionary diversification
Li, Y., Sun, C., Yates, E. A., Jiang, C., Wilkinson, M. C., & Fernig, D. G. (2016). Heparin binding preference and structures in the fibroblast growth factor family parallel their evolutionary diversification. Open Biology, 6(3). doi:10.1098/rsob.150275
Selectivity in glycosaminoglycan binding dictates the distribution and diffusion of fibroblast growth factors in the pericellular matrix
Sun, C., Marcello, M., Li, Y., Mason, D., Levy, R., & Fernig, D. G. (2016). Selectivity in glycosaminoglycan binding dictates the distribution and diffusion of fibroblast growth factors in the pericellular matrix. OPEN BIOLOGY, 6(03), 17 pages. doi:10.1098/rsob.150277
Fibroblast growth factors as tissue repair and regeneration therapeutics
Nunes, Q. M., Li, Y., Sun, C., Kinnunen, T. K., & Fernig, D. G. (2016). Fibroblast growth factors as tissue repair and regeneration therapeutics. PEERJ, 4. doi:10.7717/peerj.1535
2015
Fibroblast growth factors as tissue repair and regeneration therapeutics
Nunes, Q., Li, Y., Sun, C., Kinnunen, T., & Fernig, D. (2015). Fibroblast growth factors as tissue repair and regeneration therapeutics. doi:10.7287/peerj.preprints.1378v1
Fibroblast growth factors as tissue repair and regeneration therapeutics
Cytokines and growth factors cross-link heparan sulfate
Migliorini, E., Thakar, D., Kuehnle, J., Sadir, R., Dyer, D. P., Li, Y., . . . Richter, R. P. (2015). Cytokines and growth factors cross-link heparan sulfate. OPEN BIOLOGY, 5(8). doi:10.1098/rsob.150046
Photothermal raster image correlation spectroscopy of gold nanoparticles in solution and on live cells
Nieves, D., Li, Y., Fernig, D., & Levy, R. (2015). Photothermal raster image correlation spectroscopy of gold nanoparticles in solution and on live cells. Royal Society Open Science, 2. doi:10.1098/rsos.140454
HaloTag is an effective expression and solubilisation fusion partner for a range of fibroblast growth factors
Sun, C., Li, Y., Taylor, S. E., Mao, X., Wilkinson, M. C., & Fernig, D. G. (2015). HaloTag is an effective expression and solubilisation fusion partner for a range of fibroblast growth factors. PEERJ, 3. doi:10.7717/peerj.1060
2014
HaloTag is an effective expression and solubilisation fusion partner for a range of fibroblast growth factors
Undated
Specificities of the interaction of fibroblast growth factor and heparan sulfate
Li, Y. (n.d.). Specificities of the interaction of fibroblast growth factor and heparan sulfate. (PhD Thesis, University of Liverpool).