Research outputs
2026
Empirical treatment with valganciclovir in infants living with HIV and hospitalised with severe pneumonia in Africa: a multicentre, open-label, factorial, randomised, controlled, superiority trial.
Moraleda, C., Tagarro, A., Domínguez-Rodríguez, S., Musiime, V., Mujuru, H., Chabala, C., . . . Empirical Clinical Trial Group. (2026). Empirical treatment with valganciclovir in infants living with HIV and hospitalised with severe pneumonia in Africa: a multicentre, open-label, factorial, randomised, controlled, superiority trial.. Lancet (London, England), S0140-6736(26)00754-3. doi:10.1016/s0140-6736(26)00754-3
Inter-attack serum GFAP and NfL remain stable over 9 years in AQP4 IgG NMOSD
Siriratnam, P., Dunai, C., Egbe Franklyn, N., Linaker, S., Wesselingh, R., Jacob, A., . . . Huda, S. (2026). Inter-attack serum GFAP and NfL remain stable over 9 years in AQP4 IgG NMOSD. JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, 5 pages. doi:10.1136/jnnp-2026-338523
The cell-mediated adaptive immune response to herpes simplex virus type 1 encephalitis: mechanisms and clinical implications
Osborne, L., Dunai, C., Huang, Y., Egbe, F. N., Turtle, L., Michael, B. D., & Ellul, M. A. (2026). The cell-mediated adaptive immune response to herpes simplex virus type 1 encephalitis: mechanisms and clinical implications. FRONTIERS IN IMMUNOLOGY, 17, 28 pages. doi:10.3389/fimmu.2026.1751672
19 Characterisation of young versus older stroke in hospitalised patients with COVID-19 infection: A UK based, multicentre, case-control study
Hilton, O., Dunai, C., Egbe, F. N., Jones, J., Wood, G. K., Russell, A. R., . . . Michael, B. (2026). 19 Characterisation of young versus older stroke in hospitalised patients with COVID-19 infection: A UK based, multicentre, case-control study. Clinical Infection in Practice, 30, 100559. doi:10.1016/j.clinpr.2026.100559
Pharmacokinetics and pharmacodynamics of valganciclovir in infants with severe HIV-associated pneumonia in Africa: a sub-study of the EMPIRICAL randomised controlled trial
Jacobs, T. G., Mumbiro, V., Tembo, J., Egbe, F. N., Moraleda, C., Beca, L. S. D. A. B., . . . Burger, D. M. (2026). Pharmacokinetics and pharmacodynamics of valganciclovir in infants with severe HIV-associated pneumonia in Africa: a sub-study of the EMPIRICAL randomised controlled trial. ECLINICALMEDICINE, 94, 10 pages. doi:10.1016/j.eclinm.2026.103899
Transmission dynamics of <i>Klebsiella pneumoniae</i> in a neonatal intensive care unit in Zambia before and after an infection control bundle
Phillips, L. T., Bates, M., Coffin, S. E., Foster-Nyarko, E., Kapasa, M., Machona, S., . . . Hamer, D. H. (2026). Transmission dynamics of <i>Klebsiella pneumoniae</i> in a neonatal intensive care unit in Zambia before and after an infection control bundle. PLOS GLOBAL PUBLIC HEALTH, 6(2), 23 pages. doi:10.1371/journal.pgph.0005965
Safety and efficacy of adjunct dexamethasone in adults with herpes simplex virus encephalitis in the UK (DexEnceph): a multicentre, observer-blind, randomised, phase 3, controlled trial
Solomon, T., Hooper, C., Easton, A., Rosala-Hallas, A., Facer, B., Moore, P., . . . Ellul, M. (2026). Safety and efficacy of adjunct dexamethasone in adults with herpes simplex virus encephalitis in the UK (DexEnceph): a multicentre, observer-blind, randomised, phase 3, controlled trial. LANCET NEUROLOGY, 25(2), 136-146. Retrieved from https://www.webofscience.com/
2025
Viral Infection and the Blood-Brain Barrier: Molecular Research Insights and Therapies
Boardman, S. A., Hetherington, C., Hughes, T., Cook, C., Galea, I., Hilton, O., . . . Michael, B. D. (2025). Viral Infection and the Blood-Brain Barrier: Molecular Research Insights and Therapies. JOURNAL OF INFECTIOUS DISEASES, 232(6), 1273-1282. doi:10.1093/infdis/jiaf455
International evaluation of the SEIZUre Risk in Encephalitis (SEIZURE) score for predicting acute seizure risk
Hughes, T., Venkatesan, A., Hetherington, C., Egbe, F. N., Netravathi, M., Thakur, K. T., . . . Michael, B. D. (2025). International evaluation of the SEIZUre Risk in Encephalitis (SEIZURE) score for predicting acute seizure risk. BMJ Open, 15(12), e099451. doi:10.1136/bmjopen-2025-099451
Patients with neurological or psychiatric complications of COVID-19 have worse long-term functional outcomes: COVID-CNS-A multicentre case-control study
Shil, R. S. K., Seed, A., Franklyn, N. E., Sargent, B. F., Wood, G. K., Huang, Y., . . . Michael, B. D. (2025). Patients with neurological or psychiatric complications of COVID-19 have worse long-term functional outcomes: COVID-CNS-A multicentre case-control study. SCIENTIFIC REPORTS, 15(1), 14 pages. doi:10.1038/s41598-024-80833-0
Post-hospitalisation COVID-19 cognitive deficits at one year are global and associated with elevated brain injury markers and grey matter volume reduction.
Wood, G. K., Sargent, B. F., Ahmad, Z. -U. -A., Tharmaratnam, K., Dunai, C., Egbe, F. N., . . . Leek, E. C. (2024). Post-hospitalisation COVID-19 cognitive deficits at one year are global and associated with elevated brain injury markers and grey matter volume reduction.. Nature medicine. doi:10.1038/s41591-024-03309-8
2024
Pulmonary SARS-CoV-2 infection leads to para-infectious immune activation in the brain
Dunai, C., Hetherington, C., Boardman, S. A., Clark, J. J., Sharma, P., Subramaniam, K., . . . Michael, B. D. (2024). Pulmonary SARS-CoV-2 infection leads to para-infectious immune activation in the brain. Frontiers in Immunology, 15. doi:10.3389/fimmu.2024.1440324
Para-infectious brain injury in COVID-19 persists at follow-up despite attenuated cytokine and autoantibody responses (vol 14, 8487, 2023)
Michael, B. D., Dunai, C., Needham, E. J., Tharmaratnam, K., Williams, R., Huang, Y., . . . Menon, D. K. (2024). Para-infectious brain injury in COVID-19 persists at follow-up despite attenuated cytokine and autoantibody responses (vol 14, 8487, 2023). NATURE COMMUNICATIONS, 15(1), 1 page. doi:10.1038/s41467-024-47320-6
2023
Outcome Of A Cohort Of Older Population With COPD, Admitted With Hypercapnaeic Respiratory Failure And Acidosis
Dushianthan, A., Temblett, P., & Bhatta, A. (2010). Outcome Of A Cohort Of Older Population With COPD, Admitted With Hypercapnaeic Respiratory Failure And Acidosis. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 181, 1 page. Retrieved from https://www.webofscience.com/
Etiology of Bacterial Sepsis and Isolate Resistance Patterns in Hospitalized Neonates in Zambia
Egbe, F. N., Cowden, C., Mwananyanda, L., Pierre, C., Mwansa, J., Lukwesa Musyani, C., . . . Bates, M. A. (2023). Etiology of Bacterial Sepsis and Isolate Resistance Patterns in Hospitalized Neonates in Zambia. PEDIATRIC INFECTIOUS DISEASE JOURNAL, 42(10), 921-926. doi:10.1097/INF.0000000000004008
Unraveling the epidemiology of <i>Mycobacterium bovis</i> using whole-genome sequencing combined with environmental and demographic data
Rossi, G., Shih, B. B. -J., Egbe, N. F., Motta, P., Duchatel, F., Kelly, R. F., . . . Muwonge, A. (2023). Unraveling the epidemiology of <i>Mycobacterium bovis</i> using whole-genome sequencing combined with environmental and demographic data. FRONTIERS IN VETERINARY SCIENCE, 10, 16 pages. doi:10.3389/fvets.2023.1086001
2022
Bovine Tuberculosis Epidemiology in Cameroon, Central Africa, Based on the Interferon-Gamma Assay
Kelly, R. F., Gordon, L. G., Egbe, N. F., Freeman, E. J., Mazeri, S., Ngwa, V. N., . . . Bronsvoort, B. M. D. C. (2022). Bovine Tuberculosis Epidemiology in Cameroon, Central Africa, Based on the Interferon-Gamma Assay. FRONTIERS IN VETERINARY SCIENCE, 9, 14 pages. doi:10.3389/fvets.2022.877541
Bovine Tuberculosis Antemortem Diagnostic Test Agreement and Disagreement in a Naturally Infected African Cattle Population
Kelly, R. F., Gonzalez Gordon, L., Egbe, N. F., Freeman, E. J., Mazeri, S., Ngwa, V. N., . . . Bronsvoort, B. M. D. C. (2022). Bovine Tuberculosis Antemortem Diagnostic Test Agreement and Disagreement in a Naturally Infected African Cattle Population. FRONTIERS IN VETERINARY SCIENCE, 9, 14 pages. doi:10.3389/fvets.2022.877534
Evaluation of SARS-CoV-2 diagnostics and risk factors associated with SARS-CoV-2 infection in Zambia
Tembo, J., Egbe, N. F., Maluzi, K., Mulonga, K., Chilufya, M., Kapata, N., . . . Bates, M. (2022). Evaluation of SARS-CoV-2 diagnostics and risk factors associated with SARS-CoV-2 infection in Zambia. INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES, 120, 150-157. doi:10.1016/j.ijid.2022.04.017
Seroepidemiology of Crimean-Congo Haemorrhagic Fever among cattle in Cameroon: Implications from a One Health perspective
Gordon, L. G., Bessell, P. R., Nkongho, E. F., Ngwa, V. N., Tanya, V. N., Sander, M., . . . Kelly, R. F. (2022). Seroepidemiology of Crimean-Congo Haemorrhagic Fever among cattle in Cameroon: Implications from a One Health perspective. PLOS NEGLECTED TROPICAL DISEASES, 16(3), 22 pages. doi:10.1371/journal.pntd.0010217
2021
The epidemiology of bacterial zoonoses in pastoral and dairy cattle in Cameroon, Central Africa
Kelly, R. F., Jennings, A., Hunt, J., Hamman, S. M., Mazeri, S., Nkongho, E. F., . . . Bronsvoort, B. M. D. C. (2021). The epidemiology of bacterial zoonoses in pastoral and dairy cattle in Cameroon, Central Africa. ZOONOSES AND PUBLIC HEALTH, 68(7), 781-793. doi:10.1111/zph.12865
Transmission patterns of rifampicin resistant <i>Mycobacterium tuberculosis</i> complex strains in Cameroon: a genomic epidemiological study
Merker, M., Egbe, N. F., Ngangue, Y. R., Vuchas, C., Kohl, T. A., Dreyer, V., . . . Sander, M. S. (2021). Transmission patterns of rifampicin resistant <i>Mycobacterium tuberculosis</i> complex strains in Cameroon: a genomic epidemiological study. BMC INFECTIOUS DISEASES, 21(1), 10 pages. doi:10.1186/s12879-021-06593-8
Inferring livestock movement networks from archived data to support infectious disease control in developing countries
Covid-19 in Africa
Tembo, J., Maluzi, K., Egbe, F., & Bates, M. (2021). Covid-19 in Africa. BMJ-BRITISH MEDICAL JOURNAL, 372, 2 pages. doi:10.1136/bmj.n457
2020
Genetic Diversity of Cameroon Cattle and a Putative Genomic Map for Resistance to Bovine Tuberculosis
Callaby, R., Kelly, R., Mazeri, S., Egbe, F., Benedictus, L., Clark, E., . . . Muwonge, A. (2020). Genetic Diversity of Cameroon Cattle and a Putative Genomic Map for Resistance to Bovine Tuberculosis. FRONTIERS IN GENETICS, 11, 17 pages. doi:10.3389/fgene.2020.550215
2019
Assessing the performance of a Fasciola gigantica serum antibody ELISA to estimate prevalence in cattle in Cameroon.
Kelly, R. F., Mazeri, S., Hartley, C., Hamman, S. M., Ngu Ngwa, V., Nkongho, E. F., . . . Williams, D. J. L. (2019). Assessing the performance of a Fasciola gigantica serum antibody ELISA to estimate prevalence in cattle in Cameroon.. BMC veterinary research, 15(1), 8. doi:10.1186/s12917-018-1762-z
Molecular Epidemiology of Mycobacterium bovis in Africa
Muwonge, A., Egbe, F., Bronsvoort, M., Areda, D. B., Hlokwe, T., & Michel, A. (2019). Molecular Epidemiology of Mycobacterium bovis in Africa. In Tuberculosis in Animals: An African Perspective (pp. 127-169). Springer Nature. doi:10.1007/978-3-030-18690-6_8
The Status of Bovine Tuberculosis in Cameroon
Awah-Ndukum, J., Egbe, N. F., & Ngu-Ngwa, V. (2019). The Status of Bovine Tuberculosis in Cameroon. In Tuberculosis in Animals: An African Perspective (pp. 283-303). Springer Nature. doi:10.1007/978-3-030-18690-6_12
2018
Association of <i>Fasciola gigantica</i> Co-infection With Bovine Tuberculosis Infection and Diagnosis in a Naturally Infected Cattle Population in Africa
Kelly, R. F., Callaby, R., Egbe, N. F., Williams, D. J. L., Victor, N. N., Tanya, V. N., . . . Bronsvoort, B. M. D. C. (2018). Association of <i>Fasciola gigantica</i> Co-infection With Bovine Tuberculosis Infection and Diagnosis in a Naturally Infected Cattle Population in Africa. FRONTIERS IN VETERINARY SCIENCE, 5, 10 pages. doi:10.3389/fvets.2018.00214
2017
Molecular epidemiology of <i>Mycobacterium bovis</i> in Cameroon
Egbe, N. F., Muwonge, A., Ndip, L., Kelly, R. F., Sander, M., Tanya, V., . . . Bronsvoort, B. M. D. C. (2017). Molecular epidemiology of <i>Mycobacterium bovis</i> in Cameroon. SCIENTIFIC REPORTS, 7, 17 pages. doi:10.1038/s41598-017-04230-6
2016
Abattoir-based estimates of mycobacterial infections in Cameroon
Egbe, N. F., Muwonge, A., Ndip, L., Kelly, R. F., Sander, M., Tanya, V., . . . Bronsvoort, B. M. D. C. (2016). Abattoir-based estimates of mycobacterial infections in Cameroon. SCIENTIFIC REPORTS, 6, 14 pages. doi:10.1038/srep24320
Knowledge of Bovine Tuberculosis, Cattle Husbandry and Dairy Practices amongst Pastoralists and Small-Scale Dairy Farmers in Cameroon
Kelly, R. F., Hamman, S. M., Morgan, K. L., Nkongho, E. F., Ngwa, V. N., Tanya, V., . . . Bronsvoort, B. M. D. C. (2016). Knowledge of Bovine Tuberculosis, Cattle Husbandry and Dairy Practices amongst Pastoralists and Small-Scale Dairy Farmers in Cameroon. PLOS ONE, 11(1), 20 pages. doi:10.1371/journal.pone.0146538
2015
Co-infection of Malaria and Typhoid Fever in Feverish Patients in the Kumba Health District, Southwest Cameroon: Public Health Implications
Ndip, L. M., Egbe, F. N., Kimbi, H. K., Njom, H. A., & Ndip, R. N. (2015). Co-infection of Malaria and Typhoid Fever in Feverish Patients in the Kumba Health District, Southwest Cameroon: Public Health Implications. International Journal of TROPICAL DISEASE & Health, 9(4), 1-11. doi:10.9734/ijtdh/2015/18935