Research outputs
2026
Desensitisation to cow’s milk, following partially or extensively hydrolysed formulae feeding regimens, in infants with allergy to cow’s milk: the DREAM RCT Synopsis (The DREAM study)
Guibas, G., Brayshaw, E., Brown, M., Moitt, T., Raptis, G., Roberts, G., . . . Papadopoulos, N. (2026). Desensitisation to cow’s milk, following partially or extensively hydrolysed formulae feeding regimens, in infants with allergy to cow’s milk: the DREAM RCT Synopsis (The DREAM study). Efficacy and Mechanism Evaluation, 1-33. doi:10.3310/gjgg7715
2025
A randomized controlled trial of Scanning Eye trAining as a Rehabilitation Choice for Hemianopia after stroke (SEARCH)
Rowe, F. J., Brayshaw, E., Brown, M., Chatterjee, K., Drummond, A., Hazelton, C., . . . Wright, L. (2025). A randomized controlled trial of Scanning Eye trAining as a Rehabilitation Choice for Hemianopia after stroke (SEARCH). INTERNATIONAL JOURNAL OF STROKE, 20(8), 968-976. doi:10.1177/17474930251330140
2024
P-536 Using a risk-proportionate approach for the quality control of statistical programming in clinical trials
Cooper, R., Jones, A., Brown, M., Brayshaw, E., Gkioni, E., Green, J., . . . Kean, S. (2024). P-536 Using a risk-proportionate approach for the quality control of statistical programming in clinical trials. In ICTMC 2024. Edinburgh: Open Science Framework. Retrieved from https://osf.io/ngb98/
2023
Prevalence of vitamin D deficiency and modifiable risk factors in patients with Crohn's disease: A prospective observational study
Fletcher, J., Brown, M., Hewison, M., Swift, A., & Cooper, S. C. (2023). Prevalence of vitamin D deficiency and modifiable risk factors in patients with Crohn's disease: A prospective observational study. JOURNAL OF ADVANCED NURSING, 79(1), 205-214. doi:10.1111/jan.15476
2021
Protocol for an open-label feasibility study for a randomised controlled trial of vitamin D supplementation in Crohn's Disease patients with vitamin D deficiency: D-CODE Feasiblity study
Fletcher, J., Bedson, E., Brown, M., Hewison, M., Swift, A., & Cooper, S. C. (2021). Protocol for an open-label feasibility study for a randomised controlled trial of vitamin D supplementation in Crohn's Disease patients with vitamin D deficiency: D-CODE Feasiblity study. PILOT AND FEASIBILITY STUDIES, 7(1). doi:10.1186/s40814-021-00813-3
Onabotulinum toxin-A versus extended release tolterodine in the management of idiopathic overactive bladder in children: A pilot randomised controlled trial (OVERT trial)
Brown, M., Williamson, P. R., Sutton, L., Melling, C., Lewis, M., J.A.Webb, N., & Goyal, A. (2021). Onabotulinum toxin-A versus extended release tolterodine in the management of idiopathic overactive bladder in children: A pilot randomised controlled trial (OVERT trial). JOURNAL OF PEDIATRIC UROLOGY, 17(1). doi:10.1016/j.jpurol.2020.10.012
Intravenous or oral antibiotic treatment in adults and children with cystic fibrosis and <i>Pseudomonas</i> <i>aeruginosa</i> infection: the TORPEDO-CF RCT
Hewer, S. C. L., Smyth, A. R., Brown, M., Jones, A. P., Hickey, H., Kenna, D., . . . Williamson, P. R. (2021). Intravenous or oral antibiotic treatment in adults and children with cystic fibrosis and <i>Pseudomonas</i> <i>aeruginosa</i> infection: the TORPEDO-CF RCT. HEALTH TECHNOLOGY ASSESSMENT, 25(65), 1-+. doi:10.3310/hta25650
2020
Antimicrobial-impregnated central venous catheters for preventing neonatal bloodstream infection: the PREVAIL RCT
Gilbert, R., Brown, M., Faria, R., Fraser, C., Donohue, C., Rainford, N., . . . Oddie, S. J. (2020). Antimicrobial-impregnated central venous catheters for preventing neonatal bloodstream infection: the PREVAIL RCT. Health Technology Assessment, 24(57), 1-190. doi:10.3310/hta24570
Antimicrobial-impregnated central venous catheters for preventing neonatal bloodstream infection: the PREVAIL RCT.
Gilbert, R., Brown, M., Faria, R., Fraser, C., Donohue, C., Rainford, N., . . . Oddie, S. J. (2020). Antimicrobial-impregnated central venous catheters for preventing neonatal bloodstream infection: the PREVAIL RCT.. Health technology assessment (Winchester, England), 24(57), 1-190. doi:10.1093/ije/dyw098
Intravenous versus oral antibiotics for eradication of Pseudomonas aeruginosa in cystic fibrosis (TORPEDO-CF): a randomised controlled trial
Hewer, S. C. L., Smyth, A. R., Brown, M., Jones, A. P., Hickey, H., Kenna, D., . . . Grp, T. O. R. P. E. D. O. -C. F. S. (2020). Intravenous versus oral antibiotics for eradication of Pseudomonas aeruginosa in cystic fibrosis (TORPEDO-CF): a randomised controlled trial. LANCET RESPIRATORY MEDICINE, 8(10), 975-986. doi:10.1016/S2213-2600(20)30331-3
Gastric residual volume measurement in British neonatal intensive care units: a survey of practice
Dorling, J., Tume, L., Arch, B., Woolfall, K., Latten, L., Roper, L., . . . Gale, C. (2020). Gastric residual volume measurement in British neonatal intensive care units: a survey of practice. BMJ PAEDIATRICS OPEN, 4(1). doi:10.1136/bmjpo-2019-000601
Silver-impregnated, antibiotic-impregnated or non-impregnated ventriculoperitoneal shunts to prevent shunt infection: the BASICS three-arm RCT
Mallucci, C. L., Jenkinson, M. D., Conroy, E. J., Hartley, J. C., Brown, M., Moitt, T., . . . Gamble, C. (2020). Silver-impregnated, antibiotic-impregnated or non-impregnated ventriculoperitoneal shunts to prevent shunt infection: the BASICS three-arm RCT. HEALTH TECHNOLOGY ASSESSMENT, 24(17), 1-+. doi:10.3310/hta24170
2019
Antibiotic or silver versus standard ventriculoperitoneal shunts (BASICS): a multicentre, single-blinded, randomised trial and economic evaluation
Mallucci, C. L., Jenkinson, M. D., Conroy, E. J., Hartley, J. C., Brown, M., Dalton, J., . . . Gamble, C. (2019). Antibiotic or silver versus standard ventriculoperitoneal shunts (BASICS): a multicentre, single-blinded, randomised trial and economic evaluation. Lancet, 394(10208), 1530-1539. doi:10.1016/S0140-6736(19)31603-4
Gastric Residual Volume Measurement in UK PICUs: A Survey of Practice*
Tume, L. N., Arch, B., Woolfall, K., Latten, L., Deja, E., Roper, L., . . . Dorling, J. (2019). Gastric Residual Volume Measurement in UK PICUs: A Survey of Practice*. PEDIATRIC CRITICAL CARE MEDICINE, 20(8), 707-713. doi:10.1097/PCC.0000000000001944
Reducing catheter-related bloodstream infections in neonates
Brown, M., Gilbert, R., & Oddie, S. J. (2019). Reducing catheter-related bloodstream infections in neonates. LANCET CHILD & ADOLESCENT HEALTH, 3(8), E12. doi:10.1016/S2352-4642(19)30215-9
Antimicrobial-impregnated central venous catheters for prevention of neonatal bloodstream infection (PREVAIL): an open-label, parallel-group, pragmatic, randomised controlled trial
Gilbert, R., Brown, M., Rainford, N., Donohue, C., Fraser, C., Sinha, A., . . . Team, P. R. E. V. A. I. L. T. (2019). Antimicrobial-impregnated central venous catheters for prevention of neonatal bloodstream infection (PREVAIL): an open-label, parallel-group, pragmatic, randomised controlled trial. Lancet Child and Adolescent Health, 3(6), 381-390. doi:10.1016/S2352-4642(19)30114-2
WS01-1 Effectiveness of IV compared to oral eradication therapy of Pseudomonas aeruginosa in cystic fibrosis: multicentre randomised controlled trial (TORPEDO-CF)
Langton Hewer, S. C., Smyth, A. R., Jones, A. P., Brown, M., Hickey, H., Williamson, P. R., . . . Ashby, D. (2019). WS01-1 Effectiveness of IV compared to oral eradication therapy of Pseudomonas aeruginosa in cystic fibrosis: multicentre randomised controlled trial (TORPEDO-CF). Journal of Cystic Fibrosis, 18, S1. doi:10.1016/s1569-1993(19)30117-1
INTRAVENOUS VS ORAL ANTIBIOTICS FOR ERADICATION OF <i>PSEUDOMONAS AERUGINOSA</i> IN CYSTIC FIBROSIS (TORPEDO-CF): A RANDOMISED CONTROLLED TRIAL
Smyth, A. R., Hewer, L. S., Brown, M., Jones, A., Hickey, H., Kenna, D., . . . Williamson, P. (2019). INTRAVENOUS VS ORAL ANTIBIOTICS FOR ERADICATION OF <i>PSEUDOMONAS AERUGINOSA</i> IN CYSTIC FIBROSIS (TORPEDO-CF): A RANDOMISED CONTROLLED TRIAL. In PEDIATRIC PULMONOLOGY Vol. 54 (pp. S302). Retrieved from https://www.webofscience.com/
2018
Abstract P-379: EFFECT OF ANTIBIOTIC IMPREGNATED CENTRAL VENOUS CATHETERS ON SERIOUS THROMBOSIS IN THE PEDIATRIC INTENSIVE CARE SETTING
Wu, Y., Fraser, C., Brown, M., Mok, Q., & Gilbert, R. (2018). Abstract P-379: EFFECT OF ANTIBIOTIC IMPREGNATED CENTRAL VENOUS CATHETERS ON SERIOUS THROMBOSIS IN THE PEDIATRIC INTENSIVE CARE SETTING. Pediatric Critical Care Medicine, 19(6S), 164. doi:10.1097/01.pcc.0000537836.12547.e0
2017
Cost-Effectiveness of Pediatric Central Venous Catheters in the UK: A Secondary Publication from the CATCH Clinical Trial
Ridyard, C. H., Plumpton, C. O., Gilbert, R. E., & Hughes, D. A. (2017). Cost-Effectiveness of Pediatric Central Venous Catheters in the UK: A Secondary Publication from the CATCH Clinical Trial. FRONTIERS IN PHARMACOLOGY, 8. doi:10.3389/fphar.2017.00644
63 TORPEDO-CF – completion of recruitment to trial of optimal regimen for eradication of new infection with Pseudomonas aeruginosa
Hewer, S. L., Hickey, H., Jones, A., Blundell, M., & Smyth, A. R. (2017). 63 TORPEDO-CF – completion of recruitment to trial of optimal regimen for eradication of new infection with Pseudomonas aeruginosa. Journal of Cystic Fibrosis, 16, S80. doi:10.1016/s1569-1993(17)30428-9
2016
Antibiotic-impregnated catheters for prevention of bloodstream infection reply
Gilbert, R. E., Mok, Q., Millar, M., & Blundell, M. (2016). Antibiotic-impregnated catheters for prevention of bloodstream infection reply. LANCET, 388(10057), 2235-2236. doi:10.1016/S0140-6736(16)31716-0
2014
The British antibiotic and silver-impregnated catheters for ventriculoperitoneal shunts multi-centre randomised controlled trial (the BASICS trial): study protocol
Jenkinson, M. D., Gamble, C., Hartley, J. C., Hickey, H., Hughes, D., Blundell, M., . . . Mallucci, C. L. (2014). The British antibiotic and silver-impregnated catheters for ventriculoperitoneal shunts multi-centre randomised controlled trial (the BASICS trial): study protocol. TRIALS, 15. doi:10.1186/1745-6215-15-4
2013
Vemurafenib for the Treatment of Locally Advanced or Metastatic BRAF V600 Mutation-Positive Malignant Melanoma: A NICE Single Technology Appraisal
Beale, S., Dickson, R., Bagust, A., Blundell, M., Dundar, Y., Boland, A., . . . Proudlove, C. (2013). Vemurafenib for the Treatment of Locally Advanced or Metastatic BRAF V600 Mutation-Positive Malignant Melanoma: A NICE Single Technology Appraisal. PHARMACOECONOMICS, 31(12), 1121-1129. doi:10.1007/s40273-013-0094-x
Description of health problem
Brown, T., Pilkington, G., Bagust, A., Boland, A., Oyee, J., Smith, C. T., . . . Dickson, R. (2013). Description of health problem. HEALTH TECHNOLOGY ASSESSMENT, 17(31), 1-+. doi:10.3310/hta17310
Rituximab for the First-Line Maintenance Treatment of Follicular Non-Hodgkin’s Lymphoma
Greenhalgh, J., Bagust, A., Boland, A., Blundell, M., Oyee, J., Beale, S., . . . Chu, P. (2013). Rituximab for the First-Line Maintenance Treatment of Follicular Non-Hodgkin’s Lymphoma. PharmacoEconomics, 31(5), 403-413.
Erlotinib in monoterapia nel trattamento di mantenimento del carcinoma polmonare non a piccole cellule dopo chemioterapia a base di platino
Dickson, R., Bagust, A., Boland, A., Blundell, M., Davis, H., Dundar, Y., . . . Ramani, V. S. (2013). Erlotinib in monoterapia nel trattamento di mantenimento del carcinoma polmonare non a piccole cellule dopo chemioterapia a base di platino. PharmacoEconomics Italian Research Articles, 15(1), 35-44. doi:10.1007/s40276-013-0004-4
Rituximab for the First-Line Maintenance Treatment of Follicular Non-Hodgkin's Lymphoma A NICE Single Technology Appraisal
Greenhalgh, J., Bagust, A., Boland, A., Blundell, M., Oyee, J., Beale, S., . . . Chu, P. (2013). Rituximab for the First-Line Maintenance Treatment of Follicular Non-Hodgkin's Lymphoma A NICE Single Technology Appraisal. PHARMACOECONOMICS, 31(5), 403-413. doi:10.1007/s40273-013-0043-8
2011
Erlotinib Monotherapy for the Maintenance Treatment of Non-Small Cell Lung Cancer after Previous Platinum-Containing Chemotherapy A NICE Single Technology Appraisal
Dickson, R., Bagust, A., Boland, A., Blundell, M., Davis, H., Dundar, Y., . . . Ramani, V. S. (2011). Erlotinib Monotherapy for the Maintenance Treatment of Non-Small Cell Lung Cancer after Previous Platinum-Containing Chemotherapy A NICE Single Technology Appraisal. PHARMACOECONOMICS, 29(12), 1051-1062. doi:10.2165/11591600-000000000-00000
Clopidogrel and modified-release dipyridamole for the prevention of occlusive vascular events (review of Technology Appraisal No. 90): a systematic review and economic analysis
Greenhalgh, J., Bagust, A., Boland, A., Saborido, C. M., Oyee, J., Blundell, M., . . . Fisher, M. (2011). Clopidogrel and modified-release dipyridamole for the prevention of occlusive vascular events (review of Technology Appraisal No. 90): a systematic review and economic analysis. HEALTH TECHNOLOGY ASSESSMENT, 15(31), 1-+. doi:10.3310/hta15310
Comparison of protocols and registry entries to published reports for randomised controlled trials
Dwan, K., Altman, D. G., Cresswell, L., Blundell, M., Gamble, C. L., & Williamson, P. R. (2011). Comparison of protocols and registry entries to published reports for randomised controlled trials. COCHRANE DATABASE OF SYSTEMATIC REVIEWS, (1). doi:10.1002/14651858.MR000031.pub2
Erlotinib Monotherapy for the Maintenance Treatment of Non-Small Cell Lung Cancer after Previous Platinum-Containing Chemotherapy: A NICE Single Technology Appraisal
Dickson, R., Bagust, A., Boland, A., Blundell, M., Davis, H., Dundar, Y., . . . Ramani, V. (2011). Erlotinib Monotherapy for the Maintenance Treatment of Non-Small Cell Lung Cancer after Previous Platinum-Containing Chemotherapy: A NICE Single Technology Appraisal. PharmacoEconomics, 29(12), 1051-1062.
Erlotinib monotherapy for the maintenance treatment of non-small cell lung cancer (NSCLC)
Dickson, R., Bagust, A., Boland, A., Blundell, M., Brown, T., Davis, H., . . . Ramani, V. (2011). Erlotinib monotherapy for the maintenance treatment of non-small cell lung cancer (NSCLC). Health Technology Assessment, in pre.
Lapatinib and trastuzumab in combination with an aromatase inhibitor for the first-line treatment of metastatic hormone receptor-positive breast cancer which over-expresses human epidermal growth factor 2 (HER2): a systematic review and economic analysis
Fleeman, N., Bagust, A., Boland, A., Dickson, R., Dundar, Y., Moonan, M., . . . Thorp, N. (2011). Lapatinib and trastuzumab in combination with an aromatase inhibitor for the first-line treatment of metastatic hormone receptor-positive breast cancer which over-expresses human epidermal growth factor 2 (HER2): a systematic review and economic analysis. HEALTH TECHNOLOGY ASSESSMENT, 15(42), 1-+. doi:10.3310/hta15420
Rituximab for the first-line maintenance treatment of follicular non-Hodgkin's lymphoma: A Single Technology Appraisal
Greenhalgh, J., Bagust, A., Boland, A., Blundell, M., Oyee, J., Dundar, Y., . . . Chu, P. (2011). Rituximab for the first-line maintenance treatment of follicular non-Hodgkin's lymphoma: A Single Technology Appraisal.
Rituximab for the first-line maintenance treatment of follicular non-Hodgkin's lymphoma: A Single Technology Appraisal
Greenhalgh, J., Bagust, A., Boland, A., Blundell, M., Oyee, J., Dundar, Y., . . . Chu, P. (2011). Rituximab for the first-line maintenance treatment of follicular non-Hodgkin's lymphoma: A Single Technology Appraisal.
Ticagrelor for the treatment of acute coronary syndromes: A Single Technology Appraisal
Greenhalgh, J., Bagust, A., Boland, A., Blundell, M., Lai, M., Dundar, Y., . . . Fisher, M. (2011). Ticagrelor for the treatment of acute coronary syndromes: A Single Technology Appraisal.
2010
Comparison of protocols and registry entries to published reports for randomised controlled trials
Dwan, K., Altman, D. G., Blundell, M., Gamble, C. L., & Williamson, P. R. (2010). Comparison of protocols and registry entries to published reports for randomised controlled trials. In K. Dwan (Ed.). John Wiley & Sons, Ltd. doi:10.1002/14651858.mr000031
Comparison of protocols and registry entries to published reports for randomised controlled trials (Protocol)
Dwan, K., Altman, D. G., Blundell, M., Gamble, C. L., & Williamson, P. R. (2010). Comparison of protocols and registry entries to published reports for randomised controlled trials (Protocol). The Cochrane Library, (10).