Research outputs
Selected research outputs
- The clinical and microbiological utility of inhaled aztreonam lysine for the treatment of acute pulmonary exacerbations of cystic fibrosis: An open-label randomised crossover study (AZTEC-CF) (Journal article - 2021)
- The utility of established prognostic scores in COVID-19 hospital admissions: a multi-centre prospective evaluation of CURB-65, NEWS2, and qSOFA (Journal article - 2020)
- Ivacaftor Is Associated with Reduced Lung Infection by Key Cystic Fibrosis Pathogens A Cohort Study Using National Registry Data (Journal article - 2019)
- A direct comparison of decision rules for early discharge of suspected acute coronary syndromes in the era of high sensitivity troponin. (Journal article - 2019)
- Prevalence, risk factors and outcomes of cardiac disease in cystic fibrosis: A multinational retrospective cohort study. (Journal article - 2023)
- Cardiovascular benefits and safety profile of macrolide maintenance therapy inpatients with bronchiectasis (Journal article - 2025)
- Regulatory adverse drug reaction analyses support a temporal increase in psychiatric reactions after initiation of cystic fibrosis combination modulator therapies (Journal article - 2025)
- Managing an ageing cystic fibrosis population: challenges and priorities (Journal article - 2025)
- Antimicrobial resistance in chronic lung infection: the road to resistance. (Journal article - 2025)
2026
<i>ERJ Open Research</i> in 2026: progress and future directions.
Song, W. -J., & Frost, F. (2026). <i>ERJ Open Research</i> in 2026: progress and future directions.. ERJ open research, 12(1), 1856-2025. doi:10.1183/23120541.01856-2025
2025
Healthcare worker views on antimicrobial resistance in chronic respiratory disease.
Ananth, S., Adeoti, A. O., Ray, A., Middleton, P. G., Ekkelenkamp, M., Thee, S., . . . AMR-Lung Clinical Research Collaboration. (2025). Healthcare worker views on antimicrobial resistance in chronic respiratory disease.. Antimicrobial resistance and infection control, 14(1), 1. doi:10.1186/s13756-025-01515-8
The cardiovascular impact of antimicrobial resistance: insights from patients with bronchiectasis
Bucci, T., Guo, R., Kai-Hang, Y., Lip, G. Y. H., & Frost, F. (2025). The cardiovascular impact of antimicrobial resistance: insights from patients with bronchiectasis. EUROPEAN HEART JOURNAL, 46. doi:10.1093/eurheartj/ehaf784.4582
Breaking boundaries or a small piece of the puzzle: can CFTR modulators transform bronchiectasis care?
Graeber, S. Y., & Frost, F. (2025). Breaking boundaries or a small piece of the puzzle: can CFTR modulators transform bronchiectasis care?. ERJ OPEN RESEARCH, 11(6). doi:10.1183/23120541.00593-2025
New-onset atrial fibrillation in patients with acute hypercapnic respiratory failure requiring noninvasive ventilation
Essa, H., Balu, A., Amanullah, Y., Duvva, D., Burhan, H., Frost, F., . . . Lip, G. Y. H. (2025). New-onset atrial fibrillation in patients with acute hypercapnic respiratory failure requiring noninvasive ventilation. ERJ OPEN RESEARCH, 11(6). doi:10.1183/23120541.00605-2025
Risk of major cardiovascular events and all-cause death in patients with bronchiectasis and associated resistance to antimicrobial drugs
Bucci, T., Guo, R., Yiu, K. -H., Lip, G. Y. H., & Frost, F. (2025). Risk of major cardiovascular events and all-cause death in patients with bronchiectasis and associated resistance to antimicrobial drugs. EUROPEAN JOURNAL OF PREVENTIVE CARDIOLOGY, 32(15), 1427-1435. doi:10.1093/eurjpc/zwaf122
<i>Aspergillus </i>and <i>Pseudomonas </i>lung infections: that's what friends are spore
Hughes, D., & Frost, F. (2025). <i>Aspergillus </i>and <i>Pseudomonas </i>lung infections: that's what friends are spore. ERJ OPEN RESEARCH, 11(5). doi:10.1183/23120541.00421-2025
Managing an ageing cystic fibrosis population: challenges and priorities
Frost, F. J., Peckham, D. G., Felton, I. C., Snowball, J. E., Gray, R. D., Jones, A. M., . . . Duckers, J. (2025). Managing an ageing cystic fibrosis population: challenges and priorities. EUROPEAN RESPIRATORY REVIEW, 34(176). doi:10.1183/16000617.0261-2024
The use of oral anticoagulation at the time of acute COVID-19 infection and subsequent development of long-COVID/post-acute sequelae of SARS-CoV-2 infection
Frost, F., Rivera-Caravaca, J. M., & Lip, G. Y. H. (2025). The use of oral anticoagulation at the time of acute COVID-19 infection and subsequent development of long-COVID/post-acute sequelae of SARS-CoV-2 infection. JOURNAL OF THROMBOSIS AND THROMBOLYSIS, 58(4), 585-589. doi:10.1007/s11239-025-03096-0
Effects of azithromycin in young adults with cystic fibrosis: a protocol for emulating a published randomised controlled trial using registry data
Granger, E., Todd, J., Charman, S. C., Cromwell, E., Davies, G., Frost, F., . . . CF, T. E. N. C. F. T. E. N. (2025). Effects of azithromycin in young adults with cystic fibrosis: a protocol for emulating a published randomised controlled trial using registry data. BMJ OPEN, 15(3). doi:10.1136/bmjopen-2024-091357
Antimicrobial resistance in chronic lung infection: the road to resistance.
Kwok, W. C., Pates, K., Shah, A., Jackson, L., & Frost, F. (2025). Antimicrobial resistance in chronic lung infection: the road to resistance.. Thorax, thorax-2024-222396. doi:10.1136/thorax-2024-222396
Cardiovascular benefits and safety profile of macrolide maintenance therapy inpatients with bronchiectasis
Guo, R., Wat, D., Lam, S. H. M., Bucci, T., Tsang, C. T. -W., Cai, A. -P., . . . Yiu, K. -H. (2025). Cardiovascular benefits and safety profile of macrolide maintenance therapy inpatients with bronchiectasis. EUROPEAN RESPIRATORY JOURNAL, 65(3). doi:10.1183/13993003.01574-2024
ERJ Open Research at 10 years: charting for the next decade
Song, W. -J., Frost, F., & Barreiro, E. (2025). ERJ Open Research at 10 years: charting for the next decade. ERJ OPEN RESEARCH, 11(1). doi:10.1183/23120541.00098-2025
Regulatory adverse drug reaction analyses support a temporal increase in psychiatric reactions after initiation of cystic fibrosis combination modulator therapies
O'Connor, J., Nazareth, D., Wat, D., Southern, K. W., & Frost, F. (2025). Regulatory adverse drug reaction analyses support a temporal increase in psychiatric reactions after initiation of cystic fibrosis combination modulator therapies. JOURNAL OF CYSTIC FIBROSIS, 24(1), 30-32. doi:10.1016/j.jcf.2024.09.010
2024
Comparative estimate of glucose-lowering therapies on risk of incident pneumonia and severe sepsis: an analysis of real-world cohort data.
Henney, A. E., Riley, D. R., Hydes, T. J., Anson, M., Ibarburu, G. H., Frost, F., . . . Cuthbertson, D. J. (2024). Comparative estimate of glucose-lowering therapies on risk of incident pneumonia and severe sepsis: an analysis of real-world cohort data.. Thorax. doi:10.1136/thorax-2024-221906
A practical guide to the diagnosis and management of suspected Non-tuberculous Mycobacterial Pulmonary Disease (NTM-PD) in the United Kingdom
Dhasmana, D. J., Whitaker, P., van der Laan, R., & Frost, F. (2024). A practical guide to the diagnosis and management of suspected Non-tuberculous Mycobacterial Pulmonary Disease (NTM-PD) in the United Kingdom. NPJ PRIMARY CARE RESPIRATORY MEDICINE, 34(1). doi:10.1038/s41533-024-00403-9
Impact of prior oral anticoagulation therapies on post-discharge outcomes after COVID-19: Results from a global federated health network analysis.
Rivera-Caravaca, J. M., Frost, F., Marín, F., & Lip, G. Y. H. (2024). Impact of prior oral anticoagulation therapies on post-discharge outcomes after COVID-19: Results from a global federated health network analysis.. European journal of clinical investigation, e14299. doi:10.1111/eci.14299
Low-dose azithromycin prophylaxis in patients with atrial fibrillation and chronic obstructive pulmonary disease.
Bucci, T., Wat, D., Sibley, S., Wootton, D., Green, D., Pignatelli, P., . . . Frost, F. (2024). Low-dose azithromycin prophylaxis in patients with atrial fibrillation and chronic obstructive pulmonary disease.. Internal and emergency medicine. doi:10.1007/s11739-024-03653-0
Sputum Proteomics reveals unique signatures linked to key outcomes in cystic fibrosis trials
Risk of Cardiovascular Events after Acute Exacerbations of Chronic Obstructive Pulmonary Disease in Patients Receiving Long-Term Low-Dose Azithromycin
Bucci, T., Wat, D., Nazareth, D., Sibley, S., Wootton, D., Lip, G. Y. H., & Frost, F. (2024). Risk of Cardiovascular Events after Acute Exacerbations of Chronic Obstructive Pulmonary Disease in Patients Receiving Long-Term Low-Dose Azithromycin. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 209(11), 1394-1396. doi:10.1164/rccm.202309-1699LE
Cardiorespiratory Multimorbidity in People Living With Chronic Lung Disease Challenges, Opportunities, and a Concept for Optimization via an Integrated Care Approach
Frost, F., & Lip, G. Y. H. (2024). Cardiorespiratory Multimorbidity in People Living With Chronic Lung Disease Challenges, Opportunities, and a Concept for Optimization via an Integrated Care Approach. CHEST, 165(3), 500-502. doi:10.1016/j.chest.2023.11.009
Impact of chronic obstructive pulmonary disease in patients with atrial fibrillation: an analysis from the GLORIA-AF registry.
Romiti, G. F., Corica, B., Mei, D. A., Frost, F., Bisson, A., Boriani, G., . . . Lip, G. Y. H. (2024). Impact of chronic obstructive pulmonary disease in patients with atrial fibrillation: an analysis from the GLORIA-AF registry.. Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology, 26(1), euae021. doi:10.1093/europace/euae021
Risk of Death and Cardiovascular Events in Asian Patients With Atrial Fibrillation and Chronic Obstructive Pulmonary Disease: A Report From the Prospective APHRS Registry
Bucci, T., Romiti, G. F., Shantsila, A., Teo, W. -S., Park, H. -W., Shimizu, W., . . . Lip, G. Y. H. (2024). Risk of Death and Cardiovascular Events in Asian Patients With Atrial Fibrillation and Chronic Obstructive Pulmonary Disease: A Report From the Prospective APHRS Registry. JOURNAL OF THE AMERICAN HEART ASSOCIATION, 13(7). doi:10.1161/JAHA.123.032785
2023
48 Describing the epidemiological characteristics and treatment patterns of non-tuberculosis mycobacteria (NTM) infections in adults in Liverpool 2010–2022
Todd, H., Haigh, K., Frost, F., Green, D., Aston, S., Howard, A., . . . Davies, G. (2023). 48 Describing the epidemiological characteristics and treatment patterns of non-tuberculosis mycobacteria (NTM) infections in adults in Liverpool 2010–2022. Clinical Infection in Practice, 20, 100307. doi:10.1016/j.clinpr.2023.100307
Epidemiology and clinical impact of chronic obstructive pulmonary disease in patients with atrial fibrillation: findings from an european prospective observational registry
Romiti, G. F., Proietti, M., Corica, B., Mei, D. A., Vitolo, M., Frost, F., . . . Lip, G. Y. H. (2023). Epidemiology and clinical impact of chronic obstructive pulmonary disease in patients with atrial fibrillation: findings from an european prospective observational registry. EUROPEAN HEART JOURNAL, 44. Retrieved from https://www.webofscience.com/
Impact of chronic obstructive pulmonary disease on the natural history of atrial fibrillation: a report from the GLORIA-AF registry phase II & III
Romiti, G. F., Proietti, M., Corica, B., Mei, D. A., Frost, F., Bisson, A., . . . Lip, G. Y. H. (2023). Impact of chronic obstructive pulmonary disease on the natural history of atrial fibrillation: a report from the GLORIA-AF registry phase II & III. EUROPEAN HEART JOURNAL, 44. Retrieved from https://www.webofscience.com/
COMMUNITY ACQUIRED PNEUMONIA AND READMISSIONS FROM THE VIRTUAL WARD
Barber, D. S., Frost, F., Wat, D., Barry, V., Hayes, S., Rickards, E., & Sibley, S. (2023). COMMUNITY ACQUIRED PNEUMONIA AND READMISSIONS FROM THE VIRTUAL WARD. In THORAX Vol. 78 (pp. A249-A250). doi:10.1136/thorax-2023-BTSabstracts.377
Predicators of COPD exacerbation readmissions from the virtual ward
Barber, D. S., Frost, F., Wat, D., Barry, V., Hayes, S., Rickards, E., & Sibley, S. (2023). Predicators of COPD exacerbation readmissions from the virtual ward. In THORAX Vol. 78 (pp. A252). doi:10.1136/thorax-2023-BTSabstracts.380
Proteomics reveals distinct drivers of cystic fibrosis lung function and quality of life outcomes: post-hoc analysis of the AZTEC-CF study
Frost, F., Pottenger, S., Neill, D., Nazareth, D., & Fothergill, J. (2023). Proteomics reveals distinct drivers of cystic fibrosis lung function and quality of life outcomes: post-hoc analysis of the AZTEC-CF study. In THORAX Vol. 78 (pp. A21-A22). doi:10.1136/thorax-2023-BTSabstracts.30
354 Defining cardiac risk, events, and outcomes in people living with cystic fibrosis: a multisource, multinational approach
Frost, F., Wat, D., Nazareth, D., Walshaw, M., & Lip, G. (2023). 354 Defining cardiac risk, events, and outcomes in people living with cystic fibrosis: a multisource, multinational approach. Journal of Cystic Fibrosis, 22, S179. doi:10.1016/s1569-1993(23)01281-x
Does azithromycin modulate cardiovascular risk following acute pulmonary exacerbations of chronic obstructive pulmonary disease?
Frost, F., Bucci, T., Wat, D., Sibley, S., Green, D., & Lip, G. (2023). Does azithromycin modulate cardiovascular risk following acute pulmonary exacerbations of chronic obstructive pulmonary disease?. In EUROPEAN RESPIRATORY JOURNAL Vol. 62. doi:10.1183/13993003.congress-2023.PA4699
Environmental impact of a CF virtual clinic
Green, D., Fitzmaurice, T., Eason, M., Frost, F., Nazareth, D., & Walshaw, M. (2023). Environmental impact of a CF virtual clinic. In EUROPEAN RESPIRATORY JOURNAL Vol. 62. doi:10.1183/13993003.congress-2023.PA2905
Prevalence, risk factors and outcomes of cardiac disease in cystic fibrosis: A multinational retrospective cohort study.
Frost, F., Nazareth, D., Fauchier, L., Wat, D., Shelley, J., Austin, P., . . . Lip, G. Y. H. (2023). Prevalence, risk factors and outcomes of cardiac disease in cystic fibrosis: A multinational retrospective cohort study.. The European respiratory journal, 2300174. doi:10.1183/13993003.00174-2023
HEART Score Recalibration Using Higher Sensitivity Troponin T.
Khand, A. U., Backus, B., Campbell, M., Frost, F., Mullen, L., Fisher, M., . . . Mumma, B. E. (2023). HEART Score Recalibration Using Higher Sensitivity Troponin T.. Annals of emergency medicine, S0196-0644(23)00313-X. doi:10.1016/j.annemergmed.2023.04.024
EPS1.10 Prevalence, risk factors and outcomes of cardiovascular disease in cystic fibrosis: retrospective cohort study in two large patient data registries
Frost, F., Green, D., Nazareth, D., Wat, D., Greenwood, J., Ledson, M., . . . Lip, G. (2023). EPS1.10 Prevalence, risk factors and outcomes of cardiovascular disease in cystic fibrosis: retrospective cohort study in two large patient data registries. Journal of Cystic Fibrosis, 22, S39-S40. doi:10.1016/s1569-1993(23)00301-6
2022
The long-term effects of insulin use in incident cystic fibrosis-related diabetes: a target trial emulated using longitudinal national registry data
Granger, E., Keogh, R. H., & Frost, F. (2022). The long-term effects of insulin use in incident cystic fibrosis-related diabetes: a target trial emulated using longitudinal national registry data. ERJ OPEN RESEARCH, 8(4). doi:10.1183/23120541.00170-2022
Cystic fibrosis-related diabetes: an update
Frost, F., Walshaw, M. J., & Nazareth, D. (2022). Cystic fibrosis-related diabetes: an update. QJM-AN INTERNATIONAL JOURNAL OF MEDICINE, 115(9), 582-585. doi:10.1093/qjmed/hcaa256
Physical activity assessment and vascular function in adults with cystic fibrosis and their non-CF peers
Shelley, J., Boddy, L., Knowles, Z., Stewart, C., Frost, F., Nazareth, D., . . . Dawson, E. (2022). Physical activity assessment and vascular function in adults with cystic fibrosis and their non-CF peers. JOURNAL OF SPORTS SCIENCES, 40(16), 1837-1848. doi:10.1080/02640414.2022.2115224
Developing an ecological approach to physical activity promotion in adults with Cystic fibrosis
Shelley, J., Dawson, E. A., Boddy, L. M., Stewart, C. E., Frost, F., Nazareth, D., . . . Knowles, Z. R. (2022). Developing an ecological approach to physical activity promotion in adults with Cystic fibrosis. PLOS ONE, 17(8). doi:10.1371/journal.pone.0272355
Dietary interventions for managing glucose abnormalities in people with cystic fibrosis
Birch, L., Perry, R., Hamilton-Shield, J., Higgins, J. P. T., Lithander, F. E., Langton Hewer, S. C., . . . Nazareth, D. (2022). Dietary interventions for managing glucose abnormalities in people with cystic fibrosis. Cochrane Database of Systematic Reviews, 2022(6). doi:10.1002/14651858.cd014708
Challenges and opportunities in the development of novel antimicrobial therapeutics for cystic fibrosis
Barton, T. E., Frost, F., Fothergill, J. L., & Neill, D. R. (2022). Challenges and opportunities in the development of novel antimicrobial therapeutics for cystic fibrosis. JOURNAL OF MEDICAL MICROBIOLOGY, 71(12). doi:10.1099/jmm.0.001643
2021
Antibiotic therapy for chronic infection with <I>Burkholderia cepacia</I> complex in people with cystic fibrosis
Frost, F., Shaw, M., & Nazareth, D. (2021). Antibiotic therapy for chronic infection with <I>Burkholderia cepacia</I> complex in people with cystic fibrosis. COCHRANE DATABASE OF SYSTEMATIC REVIEWS, (12). doi:10.1002/14651858.CD013079.pub3
Continuous glucose monitoring systems for monitoring cystic fibrosis-related diabetes.
Toner, A., McCloy, A., Dyce, P., Nazareth, D., & Frost, F. (2021). Continuous glucose monitoring systems for monitoring cystic fibrosis-related diabetes.. The Cochrane database of systematic reviews, 11, CD013755. doi:10.1002/14651858.cd013755.pub2
RESEARCH FOR ALL: THE IMPACT OF NWCORR, A TRAINEE RESEARCH COLLABORATIVE
Randles, V., Bradley, P., Pearmain, L., Frost, F., & Ashish, A. (2021). RESEARCH FOR ALL: THE IMPACT OF NWCORR, A TRAINEE RESEARCH COLLABORATIVE. In THORAX Vol. 76 (pp. A162). doi:10.1136/thorax-2021-BTSabstracts.283
The clinical and microbiological utility of inhaled aztreonam lysine for the treatment of acute pulmonary exacerbations of cystic fibrosis: An open-label randomised crossover study (AZTEC-CF)
Frost, F., Young, G. R., Wright, L., Miah, N., Smith, D. L., Winstanley, C., . . . Nazareth, D. (2021). The clinical and microbiological utility of inhaled aztreonam lysine for the treatment of acute pulmonary exacerbations of cystic fibrosis: An open-label randomised crossover study (AZTEC-CF). JOURNAL OF CYSTIC FIBROSIS, 20(6), 994-1002. doi:10.1016/j.jcf.2020.12.012
Inpatient smoking cessation during COVID-19: a highly teachable moment
Frost, F., Maitland, K., Green, T., Clark, M., Duffy, A., & Jones, G. (2021). Inpatient smoking cessation during COVID-19: a highly teachable moment. In EUROPEAN RESPIRATORY JOURNAL Vol. 58. doi:10.1183/13993003.congress-2021.OA2581
The rapid development and deployment of a new multidisciplinary CPAP service outside of a critical care environment during the early stages of the COVID-19 pandemic.
Robinson, R. E., Nightingale, R., Frost, F., Green, T., Jones, G., Nwosu, N., . . . Gautam, M. (2021). The rapid development and deployment of a new multidisciplinary CPAP service outside of a critical care environment during the early stages of the COVID-19 pandemic.. Future healthcare journal, 8(1), e156-e159. doi:10.7861/fhj.2020-0167
INCIDENCE AND OUTCOMES OF PNEUMOTHORAX SECONDARY TO CARDIAC DEVICE INSERTION (Withdrawn Publication. See vol. 76, 2021)
Bull, A., Frost, F., & Wright, D. J. (2021). INCIDENCE AND OUTCOMES OF PNEUMOTHORAX SECONDARY TO CARDIAC DEVICE INSERTION (Withdrawn Publication. See vol. 76, 2021). In THORAX Vol. 76 (pp. A200-A201). doi:10.1136/thorax-2020-BTSabstracts.349
THE UTILITY OF ESTABLISHED PROGNOSTIC SCORES IN COVID-19 HOSPITAL ADMISSIONS: A COLLABORATIVE TRAINEE-LED, MULTI-CENTRE PROSPECTIVE EVALUATION OF CURB-65, NEWS2, AND QSOFA
Frost, F., Bradley, P., Tharmaratnam, K., & Wootton, D. (2021). THE UTILITY OF ESTABLISHED PROGNOSTIC SCORES IN COVID-19 HOSPITAL ADMISSIONS: A COLLABORATIVE TRAINEE-LED, MULTI-CENTRE PROSPECTIVE EVALUATION OF CURB-65, NEWS2, AND QSOFA. In THORAX Vol. 76 (pp. A57-A58). doi:10.1136/thorax-2020-BTSabstracts.100
Assessing the validity and applicability of the French 3-year prognostic score in the UK cystic fibrosis population - a national cohort study
Frost, F., Nazareth, D., Shaw, M., & Al-Aloul, M. (2021). Assessing the validity and applicability of the French 3-year prognostic score in the UK cystic fibrosis population - a national cohort study. TRANSPLANT INTERNATIONAL, 34(3), 436-444. doi:10.1111/tri.13805
2020
The utility of established prognostic scores in COVID-19 hospital admissions: a multi-centre prospective evaluation of CURB-65, NEWS2, and qSOFA
Bradley, P., Frost, F., Tharmaratnam, K., & Wootton, D. G. (2020). The utility of established prognostic scores in COVID-19 hospital admissions: a multi-centre prospective evaluation of CURB-65, NEWS2, and qSOFA. BMJ Open Respiratory Research, 7(1). doi:10.1101/2020.07.15.20154815
Utility of established prognostic scores in COVID-19 hospital admissions: multicentre prospective evaluation of CURB-65, NEWS2 and qSOFA
Bradley, P., Frost, F., Tharmaratnam, K., & Wootton, D. G. (2020). Utility of established prognostic scores in COVID-19 hospital admissions: multicentre prospective evaluation of CURB-65, NEWS2 and qSOFA. BMJ OPEN RESPIRATORY RESEARCH, 7(1). doi:10.1136/bmjresp-2020-000729
Continuous glucose monitoring systems for monitoring cystic fibrosis-related diabetes
Toner, A., McCloy, A., Dyce, P., Nazareth, D., & Frost, F. (2020). Continuous glucose monitoring systems for monitoring cystic fibrosis-related diabetes. Cochrane Database of Systematic Reviews. doi:10.1002/14651858.cd013755
Inhaled aztreonam lysine for the treatment of acute pulmonary exacerbations of cystic fibrosis
Frost, F. (2020, September 24). Inhaled aztreonam lysine for the treatmentof acute pulmonary exacerbations of cysticfibrosis.
Is continuous positive airway pressure (CPAP) a new standard of care for type 1 respiratory failure in COVID-19 patients? A retrospective observational study of a dedicated COVID-19 CPAP service
Nightingale, R., Nwosu, N., Kutubudin, F., Fletcher, T., Lewis, J., Frost, F., . . . Burhan, H. (2020). Is continuous positive airway pressure (CPAP) a new standard of care for type 1 respiratory failure in COVID-19 patients? A retrospective observational study of a dedicated COVID-19 CPAP service. BMJ open respiratory research, 7(1). doi:10.1136/bmjresp-2020-000639
Identification of high-risk non-ST elevation myocardial infarction at presentation to emergency department. A prospective observational cohort study in North West England.
Khand, A., Frost, F., Grainger, R., Fisher, M., Chew, P., Mullen, L., . . . Dodd, J. (2020). Identification of high-risk non-ST elevation myocardial infarction at presentation to emergency department. A prospective observational cohort study in North West England.. BMJ open, 10(6), e030128. doi:10.1136/bmjopen-2019-030128
P063 Assessing the validity and applicability of the French 3-year prognostic score in the UK cystic fibrosis population
Frost, F., Nazareth, D., & Al-Aloul, M. (2020). P063 Assessing the validity and applicability of the French 3-year prognostic score in the UK cystic fibrosis population. Journal of Cystic Fibrosis, 19, S73. doi:10.1016/s1569-1993(20)30399-4
P079 Optimisation of an approach for characterisation of the cystic fibrosis lung microbiome using whole-genome metagenomics
Wright, L. L., Nicholls, S., Quick, J., Frost, F., Nazareth, D., Loman, N., . . . Fothergill, J. L. (2020). P079 Optimisation of an approach for characterisation of the cystic fibrosis lung microbiome using whole-genome metagenomics. Journal of Cystic Fibrosis, 19, S77. doi:10.1016/s1569-1993(20)30414-8
P087 Inhaled and intravenous treatment strategies exert different effects on the lung microbiome during acute pulmonary exacerbations of cystic fibrosis: results from the AZTEC-CF study
Frost, F., Nazareth, D., Walshaw, M., Young, G., Winstanley, C., & Fothergill, J. (2020). P087 Inhaled and intravenous treatment strategies exert different effects on the lung microbiome during acute pulmonary exacerbations of cystic fibrosis: results from the AZTEC-CF study. Journal of Cystic Fibrosis, 19, S80. doi:10.1016/s1569-1993(20)30422-7
P150 Aztreonam lysine recovers lung function and improves quality of life in the treatment of acute exacerbations of cystic fibrosis: results from an open-label randomised crossover study (AZTEC-CF)
Frost, F., Fothergill, J., Winstanley, C., Walshaw, M., & Nazareth, D. (2020). P150 Aztreonam lysine recovers lung function and improves quality of life in the treatment of acute exacerbations of cystic fibrosis: results from an open-label randomised crossover study (AZTEC-CF). Journal of Cystic Fibrosis, 19, S98. doi:10.1016/s1569-1993(20)30485-9
P151 Monitoring clinical and microbiological changes in people with cystic fibrosis during the early stages of modulator therapy in an adult centre in the UK
FitzMaurice, T. S., Wright, L., Frost, F., Scott, E., Winstanley, C., Walshaw, M., . . . Fothergill, J. L. (2020). P151 Monitoring clinical and microbiological changes in people with cystic fibrosis during the early stages of modulator therapy in an adult centre in the UK. Journal of Cystic Fibrosis, 19, S98. doi:10.1016/s1569-1993(20)30486-0
P302 Developing an ecological approach to physical activity promotion in adults with cystic fibrosis
Shelley, J., Knowles, Z., Boddy, L., Stewart, C., Frost, F., Nazareth, D., . . . Daswon, E. (2020). P302 Developing an ecological approach to physical activity promotion in adults with cystic fibrosis. Journal of Cystic Fibrosis, 19, S140-S141. doi:10.1016/s1569-1993(20)30631-7
P390 Language matters: cystic fibrosis publications and their terminology
Hoodless, E., Frost, F., Walshaw, M., & Nazareth, D. (2020). P390 Language matters: cystic fibrosis publications and their terminology. Journal of Cystic Fibrosis, 19, S165. doi:10.1016/s1569-1993(20)30718-9
2019
INHALED AZTREONAM LYSINE RECOVERS LUNG FUNCTION AND IMPROVES QUALITY OF LIFE IN ACUTE PULMONARY EXACERBATIONS OF CYSTIC FIBROSIS
Frost, F., Fothergill, J., Winstanley, C., Nazareth, D., & Walshaw, M. J. (2019). INHALED AZTREONAM LYSINE RECOVERS LUNG FUNCTION AND IMPROVES QUALITY OF LIFE IN ACUTE PULMONARY EXACERBATIONS OF CYSTIC FIBROSIS. In THORAX Vol. 74 (pp. A13-A14). doi:10.1136/thorax-2019-BTSabstracts2019.26
OUTCOME OF NODULES DETECTED DURING A HEALTHY LUNG SCREENING PROJECT
Raghunath, S., Frost, F., Kutubudin, F., Mciver, A., Walshaw, M., & Ledson, M. (2019). OUTCOME OF NODULES DETECTED DURING A HEALTHY LUNG SCREENING PROJECT. In THORAX Vol. 74 (pp. A129). doi:10.1136/thorax-2019-BTSabstracts2019.217
PRE-OPERATIVE SPIROMETRY IDENTIFIES UNDIAGNOSED LUNG DISEASE IN CARDIAC PATIENTS
Peat, R., Town, S., Hawkes, S., Price, D., Frost, F., & Wat, D. (2019). PRE-OPERATIVE SPIROMETRY IDENTIFIES UNDIAGNOSED LUNG DISEASE IN CARDIAC PATIENTS. In THORAX Vol. 74 (pp. A160). doi:10.1136/thorax-2019-BTSabstracts2019.271
Ivacaftor Is Associated with Reduced Lung Infection by Key Cystic Fibrosis Pathogens A Cohort Study Using National Registry Data
Frost, F. J., Nazareth, D. S., Charman, S. C., Winstanley, C., & Walshaw, M. J. (2019). Ivacaftor Is Associated with Reduced Lung Infection by Key Cystic Fibrosis Pathogens A Cohort Study Using National Registry Data. ANNALS OF THE AMERICAN THORACIC SOCIETY, 16(11), 1375-1382. doi:10.1513/AnnalsATS.201902-122OC
Loss of incretin effect contributes to postprandial hyperglycaemia in cystic fibrosis-related diabetes
Frost, F., Jones, G. H., Dyce, P., Jackson, V., Nazareth, D., & Walshaw, M. J. (2019). Loss of incretin effect contributes to postprandial hyperglycaemia in cystic fibrosis-related diabetes. DIABETIC MEDICINE, 36(11), 1367-1374. doi:10.1111/dme.14121
A direct comparison of decision rules for early discharge of suspected acute coronary syndromes in the era of high sensitivity troponin.
Chew, P. G., Frost, F., Mullen, L., Fisher, M., Zadeh, H., Grainger, R., . . . Khand, A. (2019). A direct comparison of decision rules for early discharge of suspected acute coronary syndromes in the era of high sensitivity troponin. EUROPEAN HEART JOURNAL-ACUTE CARDIOVASCULAR CARE, 8(5), 421-431. doi:10.1177/2048872618755369
Antibiotic therapy for chronic infection with Burkholderia cepacia complex in people with cystic fibrosis.
Frost, F., Shaw, M., & Nazareth, D. (2019). Antibiotic therapy for chronic infection with Burkholderia cepacia complex in people with cystic fibrosis.. The Cochrane database of systematic reviews, 6, CD013079. doi:10.1002/14651858.cd013079.pub2
Cystic fibrosis-related diabetes: optimizing care with a multidisciplinary approach
Frost, F., Dyce, P., Ochota, A., Pandya, S., Clarke, T., Walshaw, M. J., & Nazareth, D. S. (2019). Cystic fibrosis-related diabetes: optimizing care with a multidisciplinary approach. DIABETES METABOLIC SYNDROME AND OBESITY-TARGETS AND THERAPY, 12, 545-552. doi:10.2147/DMSO.S180597
Cystic fibrosis related diabetes is not independently associated with increased <i>Stenotrophomonas maltophilia</i> infection: Longitudinal data from updates the UK CF Registry
Frost, F., Nazareth, D., Shaw, M., & Walshaw, M. J. (2019). Cystic fibrosis related diabetes is not independently associated with increased <i>Stenotrophomonas maltophilia</i> infection: Longitudinal data from updates the UK CF Registry. JOURNAL OF CYSTIC FIBROSIS, 18(2), 294-298. doi:10.1016/j.jcf.2018.10.011
AZTREONAM LYSINE INHALATION SOLUTION RECOVERS LUNG FUNCTION AND IMPROVES QUALITY OF LIFE IN TREATMENT OF ACUTE PULMONARY EXACERBATION OF CYSTIC FIBROSIS
Frost, F., Fothergill, J., Winstanley, C., Walshaw, M., & Nazareth, D. (2019). AZTREONAM LYSINE INHALATION SOLUTION RECOVERS LUNG FUNCTION AND IMPROVES QUALITY OF LIFE IN TREATMENT OF ACUTE PULMONARY EXACERBATION OF CYSTIC FIBROSIS. In PEDIATRIC PULMONOLOGY Vol. 54 (pp. S430). Retrieved from https://www.webofscience.com/
Effects of syntaxin 2, 3, and 4 on rat and human epithelial sodium channel (ENaC) in Xenopus laevis oocytes
Rauh, R., Frost, F., & Korbmacher, C. (2019). Effects of syntaxin 2, 3, and 4 on rat and human epithelial sodium channel (ENaC) in Xenopus laevis oocytes. In ACTA PHYSIOLOGICA Vol. 227. Retrieved from https://www.webofscience.com/
2018
EARLY OUTCOMES OF LUNG CANCER REFERRALS FROM THE LIVERPOOL HEALTHY LUNG PROJECT, A COMMUNITY BASED TARGETED LUNG CANCER SCREENING PILOT
Mason, S., Fidoe, D., Hill, S., Frost, F., Ledson, M. J., & Field, J. K. (2018). EARLY OUTCOMES OF LUNG CANCER REFERRALS FROM THE LIVERPOOL HEALTHY LUNG PROJECT, A COMMUNITY BASED TARGETED LUNG CANCER SCREENING PILOT. In THORAX Vol. 73 (pp. A256). doi:10.1136/thorax-2018-212555.440
FROZEN SECTION BIOPSY DOES NOT IMPROVE BENIGN RESECTION RATES IN A HIGH-PREVALENT LUNG CANCER SETTING
Dunmore, C., Frost, F., Ledson, M., Walshaw, M., & Page, R. (2018). FROZEN SECTION BIOPSY DOES NOT IMPROVE BENIGN RESECTION RATES IN A HIGH-PREVALENT LUNG CANCER SETTING. In THORAX Vol. 73 (pp. A260-A261). doi:10.1136/thorax-2018-212555.448
NON-MALIGNANT RESECTIONS FOR SUSPECTED MALIGNANCY: DO THEY REALLY REPRESENT BENIGN DISEASE?
Frost, F., Page, R., Walshaw, M. J., & Ledson, M. J. (2018). NON-MALIGNANT RESECTIONS FOR SUSPECTED MALIGNANCY: DO THEY REALLY REPRESENT BENIGN DISEASE?. In THORAX Vol. 73 (pp. A145). doi:10.1136/thorax-2018-212555.239
REDUCTIONS IN CYSTIC FIBROSIS LUNG INFECTION WITH LONG-TERM IVACAFTOR TREATMENT: A COHORT STUDY UTILISING DATA FROM THE UK CF REGISTRY
Frost, F., Nazareth, D., & Walshaw, M. J. (2018). REDUCTIONS IN CYSTIC FIBROSIS LUNG INFECTION WITH LONG-TERM IVACAFTOR TREATMENT: A COHORT STUDY UTILISING DATA FROM THE UK CF REGISTRY. In THORAX Vol. 73 (pp. A43-A44). doi:10.1136/thorax-2018-212555.77
SENSITIVITY AND SPECIFICITY OF RADIOLOGICAL FINDINGS FOR NON-TUBERCULOUS MYCOBACTERIUM PULMONARY DISEASE (NTM-PD) IN CYSTIC FIBROSIS
Yioe, V., Frost, F., Walshaw, M. J., & Wat, D. (2018). SENSITIVITY AND SPECIFICITY OF RADIOLOGICAL FINDINGS FOR NON-TUBERCULOUS MYCOBACTERIUM PULMONARY DISEASE (NTM-PD) IN CYSTIC FIBROSIS. In THORAX Vol. 73 (pp. A15). doi:10.1136/thorax-2018-212555.29
Continuous glucose monitoring guided insulin therapy is associated with improved clinical outcomes in cystic fibrosis-related diabetes
Frost, F., Dyce, P., Nazareth, D., Malone, V., & Walshaw, M. J. (2018). Continuous glucose monitoring guided insulin therapy is associated with improved clinical outcomes in cystic fibrosis-related diabetes. JOURNAL OF CYSTIC FIBROSIS, 17(6), 798-803. doi:10.1016/j.jcf.2018.05.005
Managing complications of cystic fibrosis in adults
Walshaw, M., & Frost, F. (2018). Managing complications of cystic fibrosis in adults. In Practitioner Vol. 262 (pp. 23-26).
Pulmonary function testing is safe in patients with thoracic aortic aneurysms
Frost, F., Peat, R., McWean, J., Shaw, M., Field, M., Nazareth, D., & Walshaw, M. (2018). Pulmonary function testing is safe in patients with thoracic aortic aneurysms. EUROPEAN RESPIRATORY JOURNAL, 52(5). doi:10.1183/13993003.00928-2018
BETWEEN A ROCK AND AN AIR-SPACE: PNEUMOTHORAX FOLLOWING EXTRACORPOREAL SHOCK-WAVE LITHOTRIPSY FOR RENAL STONES IN A PATIENT WITH CYSTIC FIBROSIS.
Frost, F. J., Nazareth, D., Griffiths, P., Brockelsby, C., & Walshaw, M. (2018). BETWEEN A ROCK AND AN AIR-SPACE: PNEUMOTHORAX FOLLOWING EXTRACORPOREAL SHOCK-WAVE LITHOTRIPSY FOR RENAL STONES IN A PATIENT WITH CYSTIC FIBROSIS.. Chest.
Case Report: First report of Elizabethkingia miricola infection in a patient with cystic fibrosis.
Frost, F., & Nazareth, D. (2018). Case Report: First report of <i>Elizabethkingia miricola</i> infection in a patient with cystic fibrosis.. F1000Research, 7, 440. doi:10.12688/f1000research.14441.2
Ghost of chest drain past
Frost, F., Hare, J., Holemans, J., & Walshaw, M. (2018). Ghost of chest drain past. THORAX, 73(6), 595-596. doi:10.1136/thoraxjnl-2017-210991
What's hot that the other lot got
Frost, F. (2018). What's hot that the other lot got. THORAX, 73(3), 302. doi:10.1136/thoraxjnl-2018-211506
AZTEC-CF STUDY: AZTREONAM LYSINE FOR INHALATION IN THE TREATMENT OF PULMONARY EXACERBATIONS OF CYSTIC FIBROSIS
Frost, F., Nazareth, D., & Walshaw, M. (2018). AZTEC-CF STUDY: AZTREONAM LYSINE FOR INHALATION IN THE TREATMENT OF PULMONARY EXACERBATIONS OF CYSTIC FIBROSIS. In PEDIATRIC PULMONOLOGY Vol. 53 (pp. 330). Retrieved from https://www.webofscience.com/
Case Report: First report of Elizabethkingia miricola infection in a patient with cystic fibrosis.
Frost, F., & Nazareth, D. (2018). Case Report: First report of Elizabethkingia miricola infection in a patient with cystic fibrosis.. F1000Res, 7, 440. doi:10.12688/f1000research.14441.2
Case Report: Haemolytic anaemia with ceftazidime use in a patient with cystic fibrosis.
Yong, J., Frost, F., Nazareth, D., & Walshaw, M. (2018). Case Report: Haemolytic anaemia with ceftazidime use in a patient with cystic fibrosis.. F1000Research, 7, 475. doi:10.12688/f1000research.14505.1
Diagnostic accuracy of routine coded versus 72-hour CT reporting in lung cancer
Griffiths, P., Brockelsby, C., Frost, F., Lee, X., Ledson, M., & Walshaw, M. (2018). Diagnostic accuracy of routine coded versus 72-hour CT reporting in lung cancer. In LUNG CANCER Vol. 115 (pp. S14). doi:10.1016/S0169-5002(18)30059-X
LONG-TERM IMPACT OF IVACAFTOR ON THE RESPIRATORY MICROBIOLOGY OF PEOPLE WITH CYSTIC FIBROSIS AND THE G551D MUTATION
Frost, F., Nazareth, D., Charman, S., & Walshaw, M. (2018). LONG-TERM IMPACT OF IVACAFTOR ON THE RESPIRATORY MICROBIOLOGY OF PEOPLE WITH CYSTIC FIBROSIS AND THE G551D MUTATION. In PEDIATRIC PULMONOLOGY Vol. 53 (pp. 294). Retrieved from https://www.webofscience.com/
2017
CFRD IS NOT AN INDEPENDENT RISK FACTOR FOR STENOTROPHOMONAS MALTOPHILIA ACQUISITION-5 YEAR ANALYSIS OF UK CF REGISTRY DATA
Frost, F., Nazareth, D., Walshaw, M. J., & Ledson, M. J. (2017). CFRD IS NOT AN INDEPENDENT RISK FACTOR FOR STENOTROPHOMONAS MALTOPHILIA ACQUISITION-5 YEAR ANALYSIS OF UK CF REGISTRY DATA. In THORAX Vol. 72 (pp. A218). doi:10.1136/thoraxjnl-2017-210983.390
EXTENDED CFTR SCREENING FOR PATIENTS WITH A CLINICAL DIAGNOSIS OF CF BUT ONLY ONE GENE ON INITIAL SCREENING
Frost, F., Griffiths, P., Ledson, M. J., Walshaw, M. J., & Nazareth, D. (2017). EXTENDED CFTR SCREENING FOR PATIENTS WITH A CLINICAL DIAGNOSIS OF CF BUT ONLY ONE GENE ON INITIAL SCREENING. In THORAX Vol. 72 (pp. A216). doi:10.1136/thoraxjnl-2017-210983.386
GENDER AND HEIGHT DRIVE VARIATION BETWEEN FORCED VITAL CAPACITY REFERENCE EQUATIONS: IMPLICATIONS FOR IPF TREATMENT
Frost, F., Peat, R., Town, S., Brockelsby, C., Johns, L., & Hilal, E. (2017). GENDER AND HEIGHT DRIVE VARIATION BETWEEN FORCED VITAL CAPACITY REFERENCE EQUATIONS: IMPLICATIONS FOR IPF TREATMENT. In THORAX Vol. 72 (pp. A167). doi:10.1136/thoraxjnl-2017-210983.296
HYPOXIC CHALLENGE TEST (HCT) FOR IN-FLIGHT OXYGEN ASSESSMENTS CAN BE AVOIDED IN PATIENTS WITH LUNG DISEASE AND LOW RESTING PAO2
Peat, R., Frost, F., Waldron, K., Furlong, J., Russell, D., & Wat, D. (2017). HYPOXIC CHALLENGE TEST (HCT) FOR IN-FLIGHT OXYGEN ASSESSMENTS CAN BE AVOIDED IN PATIENTS WITH LUNG DISEASE AND LOW RESTING PAO2. In THORAX Vol. 72 (pp. A160). doi:10.1136/thoraxjnl-2017-210983.284
MODIFIED HEART SCORE IMPROVES EARLY, SAFE DISCHARGE FOR SUSPECTED ACUTE CORONARY SYNDROMES: A PROSPECTIVE COHORT STUDY WITH RECALIBRATION OF RISK SCORES TO UNDETECTABLE HIGH SENSITIVITY TROPONIN T LIMITS
Khand, A., Frost, F., Chew, P., Fisher, M., Mullen, L., Grainger, R., . . . Dodd, J. (2017). MODIFIED HEART SCORE IMPROVES EARLY, SAFE DISCHARGE FOR SUSPECTED ACUTE CORONARY SYNDROMES: A PROSPECTIVE COHORT STUDY WITH RECALIBRATION OF RISK SCORES TO UNDETECTABLE HIGH SENSITIVITY TROPONIN T LIMITS. In JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY Vol. 69 (pp. 238). doi:10.1016/S0735-1097(17)33627-6
CLINICAL SIGNIFICANCE OF <i>ELIZABETHKINGIA MIRICOLA</i> IN CYSTIC FIBROSIS
Nazareth, D., Frost, F., Greenwood, J., & Walshaw, M. (2017). CLINICAL SIGNIFICANCE OF <i>ELIZABETHKINGIA MIRICOLA</i> IN CYSTIC FIBROSIS. In PEDIATRIC PULMONOLOGY Vol. 52 (pp. S346-S347). Retrieved from https://www.webofscience.com/
High sensitivity troponin T in combination with risk scores for suspected acute coronary syndromes: An comprehensive evaluation of HEART, TIMI and GRACE scores
Frost, F., Chew, P. G. C., Mullen, L., Fisher, M. F., Grainger, R. G., Dodd, J. P., . . . Khand, A. (2017). High sensitivity troponin T in combination with risk scores for suspected acute coronary syndromes: An comprehensive evaluation of HEART, TIMI and GRACE scores. In EUROPEAN HEART JOURNAL Vol. 38 (pp. 585-586). Retrieved from https://www.webofscience.com/
IS TRANSMISSABLE <i>PSEUDOMONAS AERUGINOSA</i> A RISK FACTOR FOR PNEUMOTHORAX IN CF?
Nazareth, D., Frost, F., Mohan, K., Greenwood, J., Cullen, D., & Walshaw, M. (2017). IS TRANSMISSABLE <i>PSEUDOMONAS AERUGINOSA</i> A RISK FACTOR FOR PNEUMOTHORAX IN CF?. In PEDIATRIC PULMONOLOGY Vol. 52 (pp. S389). Retrieved from https://www.webofscience.com/
LONG TERM MICROBIOLOGICAL OUTCOMES OF IVACAFTOR USE. A SINGLE-CENTRE RETROSPECTIVE STUDY
McCullagh, M., Wright, L., Frost, F., Greenwood, J., Nazareth, D., & Walshaw, M. (2017). LONG TERM MICROBIOLOGICAL OUTCOMES OF IVACAFTOR USE. A SINGLE-CENTRE RETROSPECTIVE STUDY. In PEDIATRIC PULMONOLOGY Vol. 52 (pp. S346). Retrieved from https://www.webofscience.com/
2016
Measurement of cardiac troponin for exclusion of myocardial infarction
Mullen, L., Chew, P. G., Frost, F., Obafemi, T., & Khand, A. (2016). Measurement of cardiac troponin for exclusion of myocardial infarction. LANCET, 387(10035), 2288-2289. doi:10.1016/S0140-6736(16)30685-7
Hyperenhancement of the Pericardium on Cardiac Magnetic Resonance Imaging: A Marker of Acute Inflammation and Neovascularization or a Chronic Fibrotic State?
Mullen, L., Chew, P. G., Frost, F., Ahmed, A., & Khand, A. (2016). Hyperenhancement of the Pericardium on Cardiac Magnetic Resonance Imaging: A Marker of Acute Inflammation and Neovascularization or a Chronic Fibrotic State?. CARDIOLOGY, 133(4), 239-241. doi:10.1159/000442409
2005
Inflammatory C-reactive protein and cytokine levels in asymptomatic people with chronic spinal cord injury
Frost, F., Roach, M. J., Kushner, I., & Schreiber, P. (2005). Inflammatory C-reactive protein and cytokine levels in asymptomatic people with chronic spinal cord injury. In ARCHIVES OF PHYSICAL MEDICINE AND REHABILITATION Vol. 86 (pp. 312-317). doi:10.1016/j.apmr.2004.02.009
1984
HYPERTENSIVE MATERNAL DEATHS IN WASHINGTON STATE
BENEDETTI, T. J., STARZYK, P., & FROST, F. (1984). HYPERTENSIVE MATERNAL DEATHS IN WASHINGTON STATE. In CLINICAL AND EXPERIMENTAL HYPERTENSION PART B-HYPERTENSION IN PREGNANCY Vol. 3 (pp. 422). Retrieved from https://www.webofscience.com/