Publications
Selected publications
- Fast approximate inference for multivariate longitudinal data (Journal article - 2023)
- Performance of the Innova SARS-CoV-2 antigen rapid lateral flow test in the Liverpool asymptomatic testing pilot: population based cohort study (Journal article - 2021)
- Dynamic longitudinal discriminant analysis using multiple longitudinal markers of different types (Journal article - 2018)
- Rapid antigen testing in COVID-19 management for school-aged children: an observational study in Cheshire and Merseyside, UK (Journal article - 2023)
- Daily testing of contacts of SARS-CoV-2 infected cases as an alternative to quarantine for key workers in Liverpool: A prospective cohort study (Journal article - 2022)
- COVID-19 risk-mitigation in reopening mass cultural events: population-based observational study for the UK Events Research Programme in Liverpool City Region (Journal article - 2024)
- Association of SARS-CoV-2 viral load distributions with individual demographics and suspected variant type: Results from the Liverpool Community Testing Pilot - England, 6 November 2020‒8 September 2021 (Journal article - 2023)
- Dynamic classification using credible intervals in longitudinal discriminant analysis (Journal article - 2017)
2024
Personalised antimicrobial susceptibility testing with clinical prediction modelling informs appropriate antibiotic use.
Howard, A., Hughes, D. M., Green, P. L., Velluva, A., Gerada, A., Maskell, S., . . . Hope, W. (2024). Personalised antimicrobial susceptibility testing with clinical prediction modelling informs appropriate antibiotic use.. Nature communications, 15(1), 9924. doi:10.1038/s41467-024-54192-3
Can self-testing be enhanced to hasten safe return of healthcare workers in pandemics? Random order, open label trial using two manufacturers' SARS-CoV-2 lateral flow devices concurrently and nested viral culture study.
Zhang, X., Cheyne, C. P., Jones, C., Humann, M., Leeming, G., Smith, C., . . . Buchan, I. E. (2024). Can self-testing be enhanced to hasten safe return of healthcare workers in pandemics? Random order, open label trial using two manufacturers' SARS-CoV-2 lateral flow devices concurrently and nested viral culture study.. BMC infectious diseases, 24(1), 1276. doi:10.1186/s12879-024-10155-z
Contact X-ray Brachytherapy as a sole treatment in selected patients with early rectal cancer - Multi-centre study.
Wah Than, N., Mark Pritchard, D., Hughes, D. M., Shing Yu, K., Minnaar, H. S., Dhadda, A., . . . Sun Myint, A. (2024). Contact X-ray Brachytherapy as a sole treatment in selected patients with early rectal cancer - Multi-centre study.. In Clinical and translational radiation oncology Vol. 49 (pp. 100851). doi:10.1016/j.ctro.2024.100851
Efficacy of providing energy expenditure information to guide weight loss interventions in people with obesity: A randomized controlled trial.
Lim, J. Z. M., Williams, A., Burgess, J., O'Connell, J., James, M., Cross, A., . . . Wilding, J. P. H. (2024). Efficacy of providing energy expenditure information to guide weight loss interventions in people with obesity: A randomized controlled trial.. Clinical obesity, e12703. doi:10.1111/cob.12703
Bayesian estimation of the prevalence of antimicrobial resistance: a mathematical modelling study.
Howard, A., Green, P. L., Velluva, A., Gerada, A., Hughes, D. M., Brookfield, C., . . . Buchan, I. (2024). Bayesian estimation of the prevalence of antimicrobial resistance: a mathematical modelling study.. The Journal of antimicrobial chemotherapy, dkae230. doi:10.1093/jac/dkae230
Lower hepatocellular carcinoma surveillance in metabolic dysfunction-associated steatotic liver disease: Impact on treatment eligibility.
Henry-Blake, C., Balachandrakumar, V., Kassab, M., Devonport, J., Matthews, C., Fox, J., . . . Cross, T. J. S. (2024). Lower hepatocellular carcinoma surveillance in metabolic dysfunction-associated steatotic liver disease: Impact on treatment eligibility.. Journal of gastroenterology and hepatology. doi:10.1111/jgh.16727
Sequence of Contact X-ray Brachytherapy (CXB) and External Beam Radiation (EBRT) in organ-preserving treatment for small rectal cancer
Than, N. W., Pritchard, D. M., Hughes, D. M., Duckworth, C. A., Wong, H., Ul Haq, M., . . . Myint, A. S. (2024). Sequence of Contact X-ray Brachytherapy (CXB) and External Beam Radiation (EBRT) in organ-preserving treatment for small rectal cancer. Radiotherapy and Oncology, 110465. doi:10.1016/j.radonc.2024.110465
Risk of type 2 diabetes, MASLD and cardiovascular disease in people living with polycystic ovary syndrome.
Henney, A. E., Gillespie, C. S., Lai, J. Y. M., Schofield, P., Riley, D. R., Caleyachetty, R., . . . Cuthbertson, D. J. (2024). Risk of type 2 diabetes, MASLD and cardiovascular disease in people living with polycystic ovary syndrome.. The Journal of clinical endocrinology and metabolism, dgae481. doi:10.1210/clinem/dgae481
The use of parent-completed questionnaires to investigate developmental outcomes in large populations of children exposed to antiseizure medications in pregnancy.
Bluett-Duncan, M., Bullen, P., Campbell, E., Clayton-Smith, J., Craig, J., García-Fiñana, M., . . . Bromley, R. L. (2024). The use of parent-completed questionnaires to investigate developmental outcomes in large populations of children exposed to antiseizure medications in pregnancy.. Epilepsia, 65(7), 2017-2029. doi:10.1111/epi.18001
Can self-testing be enhanced to hasten safe return of healthcare workers in pandemics? Random order, open label trial using two manufacturers’ SARS-CoV-2 lateral flow devices concurrently
Contact X-ray brachytherapy (CXB) as a salvage treatment for rectal cancer patients who developed local tumor re-growth after watch-and-wait approach.
Than, N. W., Pritchard, D. M., Duckworth, C. A., Hughes, D. M., Wong, H., Sripadam, R., & Myint, A. S. (2024). Contact X-ray brachytherapy (CXB) as a salvage treatment for rectal cancer patients who developed local tumor re-growth after watch-and-wait approach.. Journal of contemporary brachytherapy, 16(2), 95-102. doi:10.5114/jcb.2024.139049
Letter: Estimating the baseline local recurrence rate for a brain metastasis after neurosurgical resection.
Suppree, J. S., Kannan, S., Hughes, D. M., Jenkinson, M. D., & Zakaria, R. (2024). Letter: Estimating the baseline local recurrence rate for a brain metastasis after neurosurgical resection.. Clinical & experimental metastasis, 41(2), 155-157. doi:10.1007/s10585-024-10274-6
Patient weight has diverse effects on the prescribing of different antibiotics to dogs.
Becker, S. D., & Hughes, D. M. (2024). Patient weight has diverse effects on the prescribing of different antibiotics to dogs.. Frontiers in veterinary science, 11, 1358535. doi:10.3389/fvets.2024.1358535
COVID-19 risk-mitigation in reopening mass cultural events: population-based observational study for the UK Events Research Programme in Liverpool City Region
Burnside, G., Cheyne, C. P., Leeming, G., Humann, M., Darby, A., Green, M. A., . . . Buchan, I. E. (2024). COVID-19 risk-mitigation in reopening mass cultural events: population-based observational study for the UK Events Research Programme in Liverpool City Region. Journal of the Royal Society of Medicine. doi:10.1177/01410768231182389
Corrigendum to "Cardiovascular safety of genetically proxied interleukin-5 inhibition: A mendelian randomization study" [Respir Invest 61 (2023) 149-152].
Alton, P., Hughes, D. M., & Zhao, S. S. (2024). Corrigendum to "Cardiovascular safety of genetically proxied interleukin-5 inhibition: A mendelian randomization study" [Respir Invest 61 (2023) 149-152].. Respiratory investigation, 62(1), 142. doi:10.1016/j.resinv.2023.12.002
Statin Use, Lipids, and 3-Hydroxy-3-Methyl-Glutaryl Coenzyme A Reductase Inhibition on Risk of Idiopathic Pulmonary Fibrosis.
Zhao, S. S., Alton, P., Rogers, K., & Hughes, D. M. (2024). Statin Use, Lipids, and 3-Hydroxy-3-Methyl-Glutaryl Coenzyme A Reductase Inhibition on Risk of Idiopathic Pulmonary Fibrosis.. Clinical therapeutics, 46(1), 79-81. doi:10.1016/j.clinthera.2023.10.018
2023
The predictive accuracy of cardiovascular risk prediction tools in inflammatory arthritis and psoriasis: an observational validation study using the Clinical Practice Research Datalink.
Hughes, D. M., Coronado, J. I. C., Schofield, P., Yiu, Z. Z. N., & Zhao, S. S. (2023). The predictive accuracy of cardiovascular risk prediction tools in inflammatory arthritis and psoriasis: an observational validation study using the Clinical Practice Research Datalink.. Rheumatology (Oxford, England), kead610. doi:10.1093/rheumatology/kead610
DO GENOMIC ALTERATIONS INflUENCE THE DEVELOPMENT OF BRAIN METASTASES IN ADVANCED AND METASTATIC NON-SMALL CELL LUNG CANCER? A SYSTEMATIC REVIEW AND META-ANALYSIS
Gillespie, C., Mustafa, M., Richardson, G., Alam, A., Lee, K. S., Hughes, D., . . . Zakaria, R. (2023). DO GENOMIC ALTERATIONS INflUENCE THE DEVELOPMENT OF BRAIN METASTASES IN ADVANCED AND METASTATIC NON-SMALL CELL LUNG CANCER? A SYSTEMATIC REVIEW AND META-ANALYSIS. Neuro-Oncology, 25(Supplement_3), iii6-iii7. doi:10.1093/neuonc/noad147.026
P11.02.B DO GENOMIC ALTERATIONS INFLUENCE THE DEVELOPMENT OF BRAIN METASTASES IN ADVANCED AND METASTATIC NON-SMALL CELL LUNG CANCER?
Gillespie, C. S., Mustafa, M. A., Richardson, G. E., Alam, A. M., Lee, K. S., Hughes, D. M., . . . Zakaria, R. (2023). P11.02.B DO GENOMIC ALTERATIONS INFLUENCE THE DEVELOPMENT OF BRAIN METASTASES IN ADVANCED AND METASTATIC NON-SMALL CELL LUNG CANCER?. Neuro-Oncology, 25(Supplement_2), ii71-ii72. doi:10.1093/neuonc/noad137.236
Neurodevelopment of babies born to mothers with epilepsy: A prospective observational cohort study
Bromley, R., Bullen, P., Campbell, E., Craig, J., Ingham, A., Irwin, B., . . . NaME, S. G. (2023). Neurodevelopment of babies born to mothers with epilepsy: A prospective observational cohort study. EPILEPSIA, 64(9), 2454-2471. doi:10.1111/epi.17709
An Examination of the Internal Validity of the Sino-Nasal Outcome Test-22 in Patients with Septal Deviation
Williams, S. P., Hughes, D. M., & Leong, S. C. (n.d.). An Examination of the Internal Validity of the Sino-Nasal Outcome Test-22 in Patients with Septal Deviation. European Journal of Rhinology and Allergy, 6(2), 49-54. doi:10.5152/ejra.2023.23096
Genomic alterations and the incidence of brain metastases in advanced and metastatic non-small cell lung cancer: a systematic review and meta-analysis.
Gillespie, C. S., Mustafa, M. A., Richardson, G. E., Alam, A. M., Lee, K. S., Hughes, D. M., . . . Zakaria, R. (2023). Genomic alterations and the incidence of brain metastases in advanced and metastatic non-small cell lung cancer: a systematic review and meta-analysis.. Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer, S1556-0864(23)00638-X. doi:10.1016/j.jtho.2023.06.017
Genetic liability to gastro-esophageal reflux disease, obesity, and risk of idiopathic pulmonary fibrosis.
Cotton, C., Alton, P., Hughes, D. M., & Zhao, S. S. (2023). Genetic liability to gastro-esophageal reflux disease, obesity, and risk of idiopathic pulmonary fibrosis.. Respiratory investigation, 61(3), 335-338. doi:10.1016/j.resinv.2023.02.005
Rapid antigen testing in COVID-19 management for school-aged children: an observational study in Cheshire and Merseyside, UK
Hughes, D. M., Bird, S. M., Cheyne, C. P., Ashton, M., Campbell, M. C., Garcia-Finana, M., & Buchan, I. (2023). Rapid antigen testing in COVID-19 management for school-aged children: an observational study in Cheshire and Merseyside, UK. JOURNAL OF PUBLIC HEALTH, 45(1), E38-E47. doi:10.1093/pubmed/fdac003
Cardiovascular safety of genetically proxied interleukin-5 inhibition: A mendelian randomization study
Alton, P., Hughes, D. M., & Zhao, S. S. (2023). Cardiovascular safety of genetically proxied interleukin-5 inhibition: A mendelian randomization study. RESPIRATORY INVESTIGATION, 61(2), 149-152. doi:10.1016/j.resinv.2022.12.004
Association of SARS-CoV-2 viral load distributions with individual demographics and suspected variant type: Results from the Liverpool Community Testing Pilot - England, 6 November 2020‒8 September 2021
Hughes, D., Cheyne, C., Ashton, M., Coffee, E., Crozier, A., Semple, M., . . . Garcia-Finana, M. (n.d.). Association of SARS-CoV-2 viral load distributions with individual demographics and suspected variant type: Results from the Liverpool Community Testing Pilot - England, 6 November 2020‒8 September 2021. Eurosurveillance. doi:10.2807/1560-7917.ES.2023.28.4.2200129
GC-MS Techniques Investigating Potential Biomarkers of Dying in the Last Weeks with Lung Cancer
Chapman, E. A., Baker, J., Aggarwal, P., Hughes, D. M., Nwosu, A. C., Boyd, M. T., . . . Coyle, S. (2023). GC-MS Techniques Investigating Potential Biomarkers of Dying in the Last Weeks with Lung Cancer. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 24(2). doi:10.3390/ijms24021591
Fast approximate inference for multivariate longitudinal data
Hughes, D. M., Garcia-Finana, M., & Wand, M. P. (2022). Fast approximate inference for multivariate longitudinal data. BIOSTATISTICS, 24(1), 177-192. doi:10.1093/biostatistics/kxab021
2022
Changing patterns of SARS-CoV-2 infection through Delta and Omicron waves by vaccination status, previous infection and neighbourhood deprivation: a cohort analysis of 2.7 M people
Green, M. A., Hungerford, D. J., Hughes, D. M., Garcia-Finana, M., Turtle, L., Cheyne, C., . . . Buchan, I. (2022). Changing patterns of SARS-CoV-2 infection through Delta and Omicron waves by vaccination status, previous infection and neighbourhood deprivation: a cohort analysis of 2.7 M people. BMC INFECTIOUS DISEASES, 22(1). doi:10.1186/s12879-022-07878-2
Impact of community asymptomatic rapid antigen testing on covid-19 related hospital admissions: synthetic control study
Zhang, X., Barr, B., Green, M., Hughes, D., Ashton, M., Charalampopoulos, D., . . . Buchan, I. (2022). Impact of community asymptomatic rapid antigen testing on covid-19 related hospital admissions: synthetic control study. BMJ-BRITISH MEDICAL JOURNAL, 379. doi:10.1136/bmj-2022-071374
Evaluation of the aMAP score for hepatocellular carcinoma surveillance: a realistic opportunity to risk stratify
Johnson, P. J., Innes, H., Hughes, D. M., Kalyuzhnyy, A., Kumada, T., & Toyoda, H. (2022). Evaluation of the aMAP score for hepatocellular carcinoma surveillance: a realistic opportunity to risk stratify. BRITISH JOURNAL OF CANCER, 127(7), 1263-1269. doi:10.1038/s41416-022-01851-1
Clinical prediction models assessing response to radiotherapy for rectal cancer: protocol for a systematic review.
Karageorgou, M., Hughes, D. M., Myint, A. S., Pritchard, D. M., & Bonnett, L. J. (2022). Clinical prediction models assessing response to radiotherapy for rectal cancer: protocol for a systematic review.. Diagnostic and prognostic research, 6(1), 19. doi:10.1186/s41512-022-00132-y
Daily testing of contacts of SARS-CoV-2 infected cases as an alternative to quarantine for key workers in Liverpool: A prospective cohort study
Marsden, L., Hughes, D. M., Corcoran, R., Cheyne, C. P., Ashton, M., Buchan, I., . . . Garcia-Finana, M. (2022). Daily testing of contacts of SARS-CoV-2 infected cases as an alternative to quarantine for key workers in Liverpool: A prospective cohort study. ECLINICALMEDICINE, 50. doi:10.1016/j.eclinm.2022.101519
Genetically predicted vitamin K levels and risk of osteoarthritis: Mendelian randomization study
Zhao, S. S., Bovijn, J., Hughes, D. M., Sha, T., Zeng, C., & Lyu, H. (2022). Genetically predicted vitamin K levels and risk of osteoarthritis: Mendelian randomization study. SEMINARS IN ARTHRITIS AND RHEUMATISM, 55. doi:10.1016/j.semarthrit.2022.152030
MRI thigh measurements predict whole‐body skeletal muscle mass in patients with type 2 diabetes: a comparison with DXA
Brown, E., Williams, A., Hakim, O., Wilton, M. M., Harrold, J. A., Hughes, D., . . . Cuthbertson, D. J. (2022). MRI thigh measurements predict whole‐body skeletal muscle mass in patients with type 2 diabetes: a comparison with DXA. JCSM Rapid Communications, 5(2), 149-153. doi:10.1002/rco2.70
Effectiveness of the BNT162b2 (Pfizer-BioNTech) and the ChAdOx1 nCoV-19 (Oxford-AstraZeneca) vaccines for reducing susceptibility to infection with the Delta variant (B.1.617.2) of SARS-CoV-2
Pattni, K., Hungerford, D., Adams, S., Buchan, I., Cheyne, C. P., García-Fiñana, M., . . . Sharkey, K. J. (n.d.). Effectiveness of the BNT162b2 (Pfizer-BioNTech) and the ChAdOx1 nCoV-19 (Oxford-AstraZeneca) vaccines for reducing susceptibility to infection with the Delta variant (B.1.617.2) of SARS-CoV-2. BMC Infectious Diseases, 22(1). doi:10.1186/s12879-022-07239-z
2021
Depression and anxiety symptoms at TNF inhibitor initiation are associated with impaired treatment response in axial spondyloarthritis
Zhao, S. S., Jones, G. T., Hughes, D. M., Moots, R. J., & Goodson, N. J. (2021). Depression and anxiety symptoms at TNF inhibitor initiation are associated with impaired treatment response in axial spondyloarthritis. RHEUMATOLOGY, 60(12), 5734-5742. doi:10.1093/rheumatology/keab242
Body fat composition and risk of rheumatoid arthritis: Mendelian randomization study
Zhao, S. S., Maglio, C., Hughes, D. M., & Cook, J. P. (2021). Body fat composition and risk of rheumatoid arthritis: Mendelian randomization study. ARTHRITIS & RHEUMATOLOGY, 73(10), 1943-1944. doi:10.1002/art.41766
Comorbidity and response to TNF inhibitors in axial spondyloarthritis: longitudinal analysis of the BSRBR-AS
Zhao, S. S., Jones, G. T., Macfarlane, G. J., Hughes, D. M., Moots, R. J., & Goodson, N. J. (2021). Comorbidity and response to TNF inhibitors in axial spondyloarthritis: longitudinal analysis of the BSRBR-AS. RHEUMATOLOGY, 60(9), 4158-4165. doi:10.1093/rheumatology/keaa900
Performance of the Innova SARS-CoV-2 antigen rapid lateral flow test in the Liverpool asymptomatic testing pilot: population based cohort study
Garcia-Finana, M., Hughes, D. M., Cheyne, C. P., Burnside, G., Stockbridge, M., Fowler, T. A., . . . Buchan, I. (2021). Performance of the Innova SARS-CoV-2 antigen rapid lateral flow test in the Liverpool asymptomatic testing pilot: population based cohort study. BMJ-BRITISH MEDICAL JOURNAL, 374. doi:10.1136/bmj.n1637
Association between comorbidities and disease activity in axial spondyloarthritis: results from the BSRBR-AS
Zhao, S. S., Jones, G. T., Macfarlane, G. J., Hughes, D. M., Moots, R. J., & Goodson, N. J. (2021). Association between comorbidities and disease activity in axial spondyloarthritis: results from the BSRBR-AS. RHEUMATOLOGY, 60(7), 3189-3198. doi:10.1093/rheumatology/keaa768
Changes in in-hospital mortality in the first wave of COVID-19: a multicentre prospective observational cohort study using the WHO Clinical Characterisation Protocol UK
Docherty, A., Mulholland, R., Lone, N. I., Cheyne, C., De Angelis, D., Diaz-Ordaz, K., . . . Semple, M. (2021). Changes in in-hospital mortality in the first wave of COVID-19: a multicentre prospective observational cohort study using the WHO Clinical Characterisation Protocol UK. LANCET RESPIRATORY MEDICINE, 9(7), 773-785. doi:10.1016/S2213-2600(21)00175-2
Evaluating social and spatial inequalities of large scale rapid lateral flow SARS-CoV-2 antigen testing in COVID-19 management: An observational study of Liverpool, UK (November 2020 to January 2021)
Green, M. A., Garcia-Finana, M., Barr, B., Burnside, G., Cheyne, C. P., Hughes, D., . . . Buchan, I. E. (2021). Evaluating social and spatial inequalities of large scale rapid lateral flow SARS-CoV-2 antigen testing in COVID-19 management: An observational study of Liverpool, UK (November 2020 to January 2021). LANCET REGIONAL HEALTH-EUROPE, 6. doi:10.1016/j.lanepe.2021.100107
THE INCIDENCE AND PREVALENCE OF CARDIOVASCULAR DISEASES IN GOUT: A SYSTEMATIC REVIEW AND META-ANALYSIS
Cox, P., Gupta, S., Zhao, S. S., & Hughes, D. (2021). THE INCIDENCE AND PREVALENCE OF CARDIOVASCULAR DISEASES IN GOUT: A SYSTEMATIC REVIEW AND META-ANALYSIS. ANNALS OF THE RHEUMATIC DISEASES, 80, 844-845. doi:10.1136/annrheumdis-2021-eular.1425
The Stool Volatile Metabolome of Pre-Term Babies
Frau, A., Lett, L., Slater, R., Young, G. R., Stewart, C. J., Berrington, J., . . . Probert, C. (2021). The Stool Volatile Metabolome of Pre-Term Babies. MOLECULES, 26(11). doi:10.3390/molecules26113341
Predicting dying from lung cancer: Urine metabolites predict the last weeks and days of life.
Coyle, S., Chapman, E., Baker, J., Coleman, H., Norman, B., Hughes, D., . . . Probert, C. (2021). Predicting dying from lung cancer: Urine metabolites predict the last weeks and days of life.. In JOURNAL OF CLINICAL ONCOLOGY Vol. 39. doi:10.1200/JCO.2021.39.15_suppl.12030
COMORBIDITIES IN PSORIATIC ARTHRITIS: A SYSTEMATIC REVIEW AND META-ANALYSIS
Syrimi, Z. J., Gupta, S., Zhao, S. S., & Hughes, D. M. (2021). COMORBIDITIES IN PSORIATIC ARTHRITIS: A SYSTEMATIC REVIEW AND META-ANALYSIS. In RHEUMATOLOGY Vol. 60 (pp. 93-+). doi:10.1093/rheumatology/keab247.170
Diagnostic delay in axial spondyloarthritis: a systematic review and meta-analysis
Zhao, S., Pittam, B., Harrison, N. L., Ahmed, A. E., Nursiah, K., Goodson, N. J., & Hughes, D. M. (n.d.). Diagnostic delay in axial spondyloarthritis: a systematic review and meta-analysis. Rheumatology. doi:10.1093/rheumatology/keaa807
The effect of random-effects misspecification on classification accuracy
El Saeiti, R., Garcia-Finana, M., & Hughes, D. M. (2022). The effect of random-effects misspecification on classification accuracy. INTERNATIONAL JOURNAL OF BIOSTATISTICS, 18(1), 279-292. doi:10.1515/ijb-2019-0159
Performance of the Innova SARS-CoV-2 Antigen Rapid Lateral Flow Test in the Liverpool Asymptomatic Testing Pilot
García-Fiñana, M., Hughes, D. M., Cheyne, C., Burnside, G., Stockbridge, M., Fowler, T. A., . . . Buchan, I. (2021). Performance of the Innova SARS-CoV-2 Antigen Rapid Lateral Flow Test in the Liverpool Asymptomatic Testing Pilot. doi:10.2139/ssrn.3798558
Comorbidities in psoriatic arthritis: a systematic review and meta-analysis
Gupta, S., Syrimi, Z., Hughes, D. M., & Zhao, S. S. (n.d.). Comorbidities in psoriatic arthritis: a systematic review and meta-analysis. Rheumatology International. doi:10.1007/s00296-020-04775-2
Comment on: The impact of smoking on prevalence of psoriasis and psoriatic arthritis
Dey, M., Hughes, D. M., & Zhao, S. S. (2021). Comment on: The impact of smoking on prevalence of psoriasis and psoriatic arthritis. RHEUMATOLOGY, 60(1), E26. doi:10.1093/rheumatology/keaa555
Evaluating Social and Spatial Inequalities of Large Scale Rapid Lateral Flow SARS-CoV-2 Antigen Testing in COVID-19 Management: An Observational Study of Liverpool, UK (November 2020 to January 2021)
Green, M., Garcia-Finana, M., Barr, B., Burnside, G., Cheyne, C., Hughes, D., . . . Buchan, I. (2021). Evaluating Social and Spatial Inequalities of Large Scale Rapid Lateral Flow SARS-CoV-2 Antigen Testing in COVID-19 Management: An Observational Study of Liverpool, UK (November 2020 to January 2021). doi:10.2139/ssrn.3786003
LONGITUDINAL ANALYSIS OF THE METABOLOME IN EARLY LIFE IN PRETERM BABIES
Frau, A., Lett, L., Berrington, J., Slater, R., Hughes, D., Embleton, N., & Probert, C. (2021). LONGITUDINAL ANALYSIS OF THE METABOLOME IN EARLY LIFE IN PRETERM BABIES. In GUT Vol. 70 (pp. A28). doi:10.1136/gutjnl-2020-bsgcampus.50
2020
Changes in UK hospital mortality in the first wave of COVID-19: the ISARIC WHO Clinical Characterisation Protocol prospective multicentre observational cohort study
Docherty, A., Mulholland, R., Lone, N., Cheyne, C., De Angelis, D., Diaz-Ordaz, K., . . . for ISARIC4C investigators. (2020). Changes in UK hospital mortality in the first wave of COVID-19: the ISARIC WHO Clinical Characterisation Protocol prospective multicentre observational cohort study. doi:10.1101/2020.12.19.20248559
Statistics at The Zoo
Holmes, L., Edwards, K., Moss, A., Tollington, S., Fowler, A., Hughes, D., & Sudell, M. (2020). Statistics at The Zoo. Significance, 17(5), 26-29. doi:10.1111/1740-9713.01446
Comment on: Prevalence of extra-articular manifestations in psoriatic arthritis: reply
Zhao, S. S., Pittam, B., & Hughes, D. M. (2020). Comment on: Prevalence of extra-articular manifestations in psoriatic arthritis: reply. RHEUMATOLOGY, 59(9), E51-E53. doi:10.1093/rheumatology/keaa182
Faecal volatile organic compounds in preterm babies at risk of necrotising enterocolitis: the DOVE study
Probert, C., Greenwood, R., Mayor, A., Hughes, D., Aggio, R., Jackson, R. E., . . . Ewer, A. K. (2020). Faecal volatile organic compounds in preterm babies at risk of necrotising enterocolitis: the DOVE study. ARCHIVES OF DISEASE IN CHILDHOOD-FETAL AND NEONATAL EDITION, 105(5), 474-479. doi:10.1136/archdischild-2019-318221
Prevalence of extra-articular manifestations in psoriatic arthritis: a systematic review and meta-analysis
Pittam, B., Gupta, S., Harrison, N. L., Robertson, S., Hughes, D. M., & Zhao, S. S. (2020). Prevalence of extra-articular manifestations in psoriatic arthritis: a systematic review and meta-analysis. RHEUMATOLOGY, 59(9), 2199-2206. doi:10.1093/rheumatology/keaa062
AFP is elevated more than 10 years before hepatocellular carcinoma development is detected: this observation leads to a practical risk stratification strategy
Johnson, P., Berhane, S., de Groot, E., Toyoda, H., Tada, T., Kumada, T., . . . Hughes, D. M. (2020). AFP is elevated more than 10 years before hepatocellular carcinoma development is detected: this observation leads to a practical risk stratification strategy. Journal of Hepatology, 73, S387-S388. doi:10.1016/s0168-8278(20)31265-4
Systematic review and meta-analysis of diagnostic delay in axial spondyloarthritis
Zhao, S., Pittam, B., Harrison, N., Ahmed, A., Nursiah, K., Goodson, N., & Hughes, D. (2020). Systematic review and meta-analysis of diagnostic delay in axial spondyloarthritis. doi:10.21203/rs.3.rs-17943/v2
The prevalence and impact of depression in primary systemic vasculitis: a systematic review and meta-analysis
Pittam, B., Gupta, S., Ahmed, A. E., Hughes, D. M., & Zhao, S. S. (2020). The prevalence and impact of depression in primary systemic vasculitis: a systematic review and meta-analysis. Rheumatology International. doi:10.1007/s00296-020-04611-7
Serum Levels of Alpha Fetoprotein Increased More Than 10 Years Before Detection of Hepatocellular Carcinoma
Hughes, D. M., Berhane, S., Emily de Groot, C. A., Toyoda, H., Tada, T., Kumada, T., . . . Johnson, P. (2020). Serum Levels of Alpha Fetoprotein Increased More Than 10 Years Before Detection of Hepatocellular Carcinoma. Clinical Gastroenterology and Hepatology. doi:10.1016/j.cgh.2020.04.084
Impact of Smoking in Response to Tumor Necrosis Factor Inhibitors in Axial Spondyloarthritis: Methodologic Considerations for Longitudinal Observational Studies
Zhao, S. S., Yoshida, K., Jones, G. T., Hughes, D. M., Tedeschi, S. K., Lyu, H., . . . Goodson, N. J. (2020). Impact of Smoking in Response to Tumor Necrosis Factor Inhibitors in Axial Spondyloarthritis: Methodologic Considerations for Longitudinal Observational Studies. Arthritis Care and Research, 72(4), 591-599. doi:10.1002/acr.23851
Systematic review and meta-analysis of diagnostic delay in axial spondyloarthritis
Zhao, S., Pittam, B., Harrison, N. L., Nursiah, K., Goodson, N. J., & Hughes, D. M. (2020). Systematic review and meta-analysis of diagnostic delay in axial spondyloarthritis. doi:10.21203/rs.3.rs-17943/v1
Does the application of diffusion weighted imaging improve the prediction of survival in patients with resected brain metastases? A retrospective multicenter study
Zakaria, R., Chen, Y. J., Hughes, D. M., Wang, S., Chawla, S., Poptani, H., . . . Mohan, S. (2020). Does the application of diffusion weighted imaging improve the prediction of survival in patients with resected brain metastases? A retrospective multicenter study. CANCER IMAGING, 20(1). doi:10.1186/s40644-020-0295-4
AFP is elevated more than 10 years before hepatocellular carcinoma development is detected: this observation leads to a practical risk stratification strategy
Johnson, P., Berhane, S., de Groot, E., Toyoda, H., Tada, T., Kumada, T., . . . Hughes, D. M. (2020). AFP is elevated more than 10 years before hepatocellular carcinoma development is detected: this observation leads to a practical risk stratification strategy. In JOURNAL OF HEPATOLOGY Vol. 73 (pp. S387-S388). Retrieved from https://www.webofscience.com/
2019
Comorbidity burden in axial spondyloarthritis: a cluster analysis
Zhao, S. S., Radner, H., Siebert, S., Duffield, S., Thong, D., Hughes, D. M., . . . Goodson, N. (2019). Comorbidity burden in axial spondyloarthritis: a cluster analysis. Rheumatology, 58(10), 1746-1754. doi:10.1093/rheumatology/kez119
Smoking does not protect patients with axial spondyloarthritis from attacks of uveitis
Zhao, S. S., Macfarlane, G. J., Jones, G. T., Gaffney, K., Hughes, D. M., Moots, R. J., & Goodson, N. J. (2019). Smoking does not protect patients with axial spondyloarthritis from attacks of uveitis. ANNALS OF THE RHEUMATIC DISEASES, 78(9), 1287-+. doi:10.1136/annrheumdis-2019-215348
Response: To statistical significance and beyond
Zhao, S. S., & Hughes, D. M. (2019). Response: To statistical significance and beyond. CLINICAL RHEUMATOLOGY, 38(8), 2285-2286. doi:10.1007/s10067-019-04630-1
Smoking status and cause-specific discontinuation of tumour necrosis factor inhibitors in axial spondyloarthritis
Zhao, S. S., Yoshida, K., Jones, G. T., Hughes, D. M., Duffield, S. J., Tedeschi, S. K., . . . Goodson, N. J. (2019). Smoking status and cause-specific discontinuation of tumour necrosis factor inhibitors in axial spondyloarthritis. ARTHRITIS RESEARCH & THERAPY, 21. doi:10.1186/s13075-019-1958-z
Seasonal variations of Google searches for joint swelling: implications for patient-reported outcomes
Zhao, S., Duffield, S. J., & Hughes, D. M. (2019). Seasonal variations of Google searches for joint swelling: implications for patient-reported outcomes. CLINICAL RHEUMATOLOGY, 38(6), 1791-1792. doi:10.1007/s10067-019-04534-0
Rapid Scotch Whisky Analysis and Authentication using Desorption Atmospheric Pressure Chemical Ionisation Mass Spectrometry
Smith, B. L., Hughes, D. M., Badu-Tawiah, A. K., Eccles, R., Goodall, I., & Maher, S. (2019). Rapid Scotch Whisky Analysis and Authentication using Desorption Atmospheric Pressure Chemical Ionisation Mass Spectrometry. Scientific Reports, 9. doi:10.1038/s41598-019-44456-0
Associations between smoking and extra-axial manifestations and disease severity in axial spondyloarthritis: results from the British Society for Rheumatology Biologics Register for Ankylosing Spondylitis (BSRBR-AS)
Zhao, S., Jones, G. T., Macfarlane, G. J., Hughes, D. M., Dean, L. E., Moots, R. J., & Goodson, N. (2019). Associations between smoking and extra-axial manifestations and disease severity in axial spondyloarthritis: results from the British Society for Rheumatology Biologics Register for Ankylosing Spondylitis (BSRBR-AS). Rheumatology, 58(5), 811-819. doi:10.1093/rheumatology/key371
Identifying patients who will not reachieve remission after breakthrough seizures
Hughes, D. M., Bonnett, L. J., Marson, A. G., & Garcia-Finana, M. (2019). Identifying patients who will not reachieve remission after breakthrough seizures. EPILEPSIA, 60(4), 774-782. doi:10.1111/epi.14697
O35 Multimorbidity in patients with axial spondyloarthritis: a cluster analysis
Zhao, S., Radner, H., Thong, D., Duffield, S. J., Hughes, D. M., Moots, R. J., . . . Siebert, S. (2019). O35 Multimorbidity in patients with axial spondyloarthritis: a cluster analysis. Rheumatology, 58(Supplement_3). doi:10.1093/rheumatology/kez105.034
50 Volatile organic compounds predict the last week of life in lung cancer patients
Coyle, S., Chapman, E., Mason, S., Hughes, D., Boyd, M., Probert, C., & Ellershaw, J. (2019). 50 Volatile organic compounds predict the last week of life in lung cancer patients. In Poster presentations (pp. A27.2-A27). British Medical Journal Publishing Group. doi:10.1136/bmjspcare-2019-asp.73
Personalized risk‐based screening for diabetic retinopathy: A multivariate approach versus the use of stratification rules
Garcia-Finana, M., Hughes, D., Cheyne, C. P., Broadbent, D. M., wang., Wang, A., . . . Harding, S. (2019). Personalized risk‐based screening for diabetic retinopathy: A multivariate approach versus the use of stratification rules. Diabetes, Obesity and Metabolism, 21(3), 560-568. doi:10.1111/dom.13552
MULTIMORBIDITY IN PATIENTS WITH AXIAL SPONDYLOARTHRITIS: A CLUSTER ANALYSIS
Zhao, S., Radner, H., Thong, D., Duffield, S. J., Hughes, D. M., Moots, R. J., . . . Siebert, S. (2019). MULTIMORBIDITY IN PATIENTS WITH AXIAL SPONDYLOARTHRITIS: A CLUSTER ANALYSIS. In RHEUMATOLOGY Vol. 58. Retrieved from https://www.webofscience.com/
2018
Modelling Multivariate Longitudinal Markers using Variational Bayes
Hughes, D. M. (2018). Modelling Multivariate Longitudinal Markers using Variational Bayes. Reading, UK.
Variational Approximations of Multivariate Generalized Linear Mixed Models.
Hughes, D. M. (2018). Variational Approximations of Multivariate Generalized Linear Mixed Models.. Department of Statistics, University of Leeds.
Mixed model tools for multivariate longitudinal classification in R
Hughes, D. M. (2018). Mixed model tools for multivariate longitudinal classification in R. Cardiff, UK.
Fitting Multivariate Generalised Linear Mixed Models using Variational Bayes
Hughes, D. M., & Garcia-Finana, M. (2018). Fitting Multivariate Generalised Linear Mixed Models using Variational Bayes. Melbourne.
The prevalence of depression in axial spondyloarthritis and its association with disease activity: a systematic review and meta-analysis
Zhao, S., Thong, D., Miller, N., Duffield, S., Hughes, D., Chadwick, L., & Goodson, N. (2018). The prevalence of depression in axial spondyloarthritis and its association with disease activity: a systematic review and meta-analysis. Arthritis Research and Therapy, 20. doi:10.1186/s13075-018-1644-6
Dynamic longitudinal discriminant analysis using multiple longitudinal markers of different types
Hughes, D. M., Komarek, A., Czanner, G., & Garcia-Finana, M. (2018). Dynamic longitudinal discriminant analysis using multiple longitudinal markers of different types. Statistical Methods in Medical Research, 27(7), 2060-2080. doi:10.1177/0962280216674496
Multivariate Linear Mixed Models in Large Longitudinal Datasets: A Variational Approach
Hughes, D. M., & Garcia-Finana, M. (2018). Multivariate Linear Mixed Models in Large Longitudinal Datasets: A Variational Approach. Poster session presented at the meeting of International Society for Bayesian Analysis 2018 World Meeting. Edinburgh.
A comparison of group prediction approaches in longitudinal discriminant analysis
Hughes, D. M., El Saeiti, R., & Garcia-Finana, M. (2018). A comparison of group prediction approaches in longitudinal discriminant analysis. BIOMETRICAL JOURNAL, 60(2), 307-322. doi:10.1002/bimj.201700013
Alcohol and disease activity in axial spondyloarthritis: a cross-sectional study
Zhao, S., Thong, D., Duffield, S. J., Hughes, D., & Goodson, N. J. (2018). Alcohol and disease activity in axial spondyloarthritis: a cross-sectional study. RHEUMATOLOGY INTERNATIONAL, 38(3), 375-381. doi:10.1007/s00296-018-3927-2
2017
Dynamic classification using credible intervals in longitudinal discriminant analysis
Hughes, D. M., Komarek, A., Bonnett, L. J., Czanner, G., & Garcia-Finana, M. (2017). Dynamic classification using credible intervals in longitudinal discriminant analysis. STATISTICS IN MEDICINE, 36(24), 3858-3874. doi:10.1002/sim.7397
EARLY IDENTIFICATION OF PATIENTS WITH DRUG-RESISTANT EPILEPSY
Hughes, D. M., Bonnett, L. J., Czanner, G., Komarek, A., Marson, A., & Garcia-Finana, M. (2017). EARLY IDENTIFICATION OF PATIENTS WITH DRUG-RESISTANT EPILEPSY. Poster session presented at the meeting of Unknown Conference. Retrieved from https://www.webofscience.com/
Using the past to predict the future: How useful are longitudinal measurements?
Hughes., & Garcia-Finana, M. (2017). Using the past to predict the future: How useful are longitudinal measurements?. Poster session presented at the meeting of 38th Annual Conference of the ISCB. Vigo, Spain.
Dynamic Longitudinal Discriminant Analysis: Statistical and clinical findings from The DiALog project
Hughes., Komarek, A., Bonnett, L. J., Czanner, G., Marson, A., & Garcia-Finana, M. (2017). Dynamic Longitudinal Discriminant Analysis: Statistical and clinical findings from The DiALog project. Statistical Analysis of Multi-Outcome Data (SAM) 2017.
Prediction approaches and model misspecification in longitudinal discriminant analysis
Hughes, D. M., El Saeiti, R., & Garcia-Finana, M. (2017). Prediction approaches and model misspecification in longitudinal discriminant analysis. Poster session presented at the meeting of Statistical Analysis of Multi-Outcome Data (SAM) 2017. Liverpool, UK.
Clinical classification in longitudinal discriminant analysis: A comparison of three approaches to using a patient’s longitudinal marker history.
Hughes, D. M., El Saeiti, R., & Garcia-Finana, M. (2017). Clinical classification in longitudinal discriminant analysis: A comparison of three approaches to using a patient’s longitudinal marker history.. Poster session presented at the meeting of 2017 Channel Network Conference. Hasselt, Belgium.
A novel multivariate discriminant approach to predict sight threatening diabetic retinopathy (STDR) cases - data from the Liverpool Diabetic Eye Study
Garcia-Finana, M., Hughes, D. M., Cheyne, C. P., Broadbent, D. M., Wang, A., Mobayen-Rahni, M., . . . Harding, S. P. (2017). A novel multivariate discriminant approach to predict sight threatening diabetic retinopathy (STDR) cases - data from the Liverpool Diabetic Eye Study. In INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE Vol. 58. Retrieved from https://www.webofscience.com/
The Effect of Alcohol on Disease Activity in Axial Spondyloarthritis
Zhao, S., Thong, D., Duffield, S., Hughes, D., & Goodson, N. (2017). The Effect of Alcohol on Disease Activity in Axial Spondyloarthritis. In ARTHRITIS & RHEUMATOLOGY Vol. 69. Retrieved from https://www.webofscience.com/
2016
Identifying disease progression using longitudinal discriminant analysis
Hughes., Komarek, A., Czanner, G., & Van der Hoek, M. (2016). Identifying disease progression using longitudinal discriminant analysis. Poster session presented at the meeting of 2016 Conference of the Royal Statistical Society. Manchester.
Dynamic Allocation schemes using credible intervals and multivariate generalised mixed models
Hughes., Komarek, A., Czanner, G., & Van der Hoek, M. (2016). Dynamic Allocation schemes using credible intervals and multivariate generalised mixed models. Birmingham.
Discriminant Function Analysis for Longitudinal Data (DiALog): Applications in Medical Research
Hughes., Czanner, G., Cox, T., Bonnett, L., Harding, S., Marson, A., . . . Van der Hoek, M. (2016). Discriminant Function Analysis for Longitudinal Data (DiALog): Applications in Medical Research. Poster session presented at the meeting of 2016 MRC Festival of Medical Science. Liverpool.
2015
Early Detection of Diabetic Retinopathy using Personalised Longitudinal Discriminant Analysis
Hughes, D., Czanner, G., Komarek, A., Harding, S., & Garcia Finana, M. (2015). Early Detection of Diabetic Retinopathy using Personalised Longitudinal Discriminant Analysis. Utrecht, Holland.
Flexible Discriminant Analysis Using Multivariate Mixed Models
Hughes, D., Czanner, G., Komarek, A., & Garcia Finana, M. (2015). Flexible Discriminant Analysis Using Multivariate Mixed Models. University of Warwick.
Personalised Longitudinal Discriminant Analysis for Early Detection of Diabetic Retinopathy
Hughes, D., Czanner, G., Cheyne, C., Komarek, A., Harding, S., & Garcia Finana, M. (2015). Personalised Longitudinal Discriminant Analysis for Early Detection of Diabetic Retinopathy. Poster session presented at the meeting of ITM Research Day. University of Liverpool.
2014
Monotone local linear estimation of transducer functions
Hughes, D. (2014, September 24). Monotone local linear estimation of transducer functions. (PhD Thesis, University of Liverpool).
2013
Mapping the Stability Diagram of a Quadrupole Mass Spectrometer with a Static Transverse Magnetic Field Applied
Maher, S., Syed, S. U., Hughes, D. M., Gibson, J. R., & Taylor, S. (2013). Mapping the Stability Diagram of a Quadrupole Mass Spectrometer with a Static Transverse Magnetic Field Applied. JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY, 24(8), 1307-1314. doi:10.1007/s13361-013-0654-5
Monotone local linear estimation of transducer functions
Hughes, D. (2013). Monotone local linear estimation of transducer functions. Rennes, France.
2012
Monotone Nonparametric Estimates of Psychometric Functions
Hughes, D. (2012). Monotone Nonparametric Estimates of Psychometric Functions. Southampton.
Undated
Risk of Type 2 Diabetes, Metabolic Dysfunction Associated Steatotic Liver Disease and Cardiovascular Disease in People Living with Polycystic Ovary Syndrome According to Disease Phenotype: An Analysis of Prospective Cohort and Multi-Organ Imaging Data from the UK Biobank
Henney, A. E., Gillespie, C. S., Lai, J. Y. M., Schofield, P., Riley, D., Caleyachetty, R., . . . Cuthbertson, D. J. (n.d.). Risk of Type 2 Diabetes, Metabolic Dysfunction Associated Steatotic Liver Disease and Cardiovascular Disease in People Living with Polycystic Ovary Syndrome According to Disease Phenotype: An Analysis of Prospective Cohort and Multi-Organ Imaging Data from the UK Biobank.