Research outputs
2025
The 7SK small nuclear ribonucleoprotein links the cell responses to transcription and replication stress by promoting replication fork reversal and homologous recombination
Human RNase H2 upregulation counteracts oncogene- and chemotherapy-induced replication stress.
Wilkins, R. J., Kannan, A., Plass, S. A., Wilson, C., Kelly, R. D. W., Tang, C. H. M., . . . Petermann, E. (2025). Human RNase H2 upregulation counteracts oncogene- and chemotherapy-induced replication stress.. Oncogene, 44(35), 3255-3271. doi:10.1038/s41388-025-03489-8
2024
Human RNase H2 upregulation counteracts oncogene- and chemotherapy-induced replication stress
Investigating the role of CpG island DNA methylation at 3’UTRs in cancer
Proteomics couples electrical remodelling to inflammation in a murine model of heart failure with sinus node dysfunction.
Kahnert, K., Soattin, L., Mills, R. W., Wilson, C., Maurya, S., Sorrentino, A., . . . Lundby, A. (2024). Proteomics couples electrical remodelling to inflammation in a murine model of heart failure with sinus node dysfunction.. Cardiovascular research, 120(8), 927-942. doi:10.1093/cvr/cvae054
2023
Atrioventricular node dysfunction in pressure overload-induced heart failure-Involvement of the immune system and transcriptomic remodelling
Wilson, C., Zi, M., Smith, M., Hussain, M., D'Souza, A., Dobrzynski, H., & Boyett, M. R. (2023). Atrioventricular node dysfunction in pressure overload-induced heart failure-Involvement of the immune system and transcriptomic remodelling. FRONTIERS IN PHARMACOLOGY, 14. doi:10.3389/fphar.2023.1083910
2022
Cardiomyocyte-specific loss of plasma membrane calcium ATPase 1 impacts cardiac rhythm and is associated with ventricular repolarisation dysfunction
Wilson, C., Stafford, N., Zi, M., Chelu, A., Niort, B. C., Li, Y., . . . Cartwright, E. J. (2022). Cardiomyocyte-specific loss of plasma membrane calcium ATPase 1 impacts cardiac rhythm and is associated with ventricular repolarisation dysfunction. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY, 172, 41-51. doi:10.1016/j.yjmcc.2022.07.011
2021
Regulation of sinus node pacemaking and atrioventricular node conduction by HCN channels in health and disease
Boyett, M. R., Yanni, J., Tellez, J., Bucchi, A., Mesirca, P., Cai, X., . . . D'Souza, A. (2021). Regulation of sinus node pacemaking and atrioventricular node conduction by HCN channels in health and disease. PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY, 166, 61-85. doi:10.1016/j.pbiomolbio.2021.06.008
The Missing Link Between Cancer-Associated Variants and LncRNAs
Wilson, C., & Kanhere, A. (2021). The Missing Link Between Cancer-Associated Variants and LncRNAs. TRENDS IN GENETICS, 37(5), 410-413. doi:10.1016/j.tig.2021.01.010
A long intergenic non-coding RNA regulates nuclear localization of DNA methyl transferase-1
Jones, R., Wijesinghe, S., Wilson, C., Halsall, J., Liloglou, T., & Kanhere, A. (2021). A long intergenic non-coding RNA regulates nuclear localization of DNA methyl transferase-1. ISCIENCE, 24(4). doi:10.1016/j.isci.2021.102273
8q24.21 Locus: A Paradigm to Link Non-Coding RNAs, Genome Polymorphisms and Cancer
Wilson, C., & Kanhere, A. (2021). 8q24.21 Locus: A Paradigm to Link Non-Coding RNAs, Genome Polymorphisms and Cancer. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 22(3). doi:10.3390/ijms22031094
2020
Targeting Ca<SUP>2+</SUP>Handling Proteins for the Treatment of Heart Failure and Arrhythmias
Njegic, A., Wilson, C., & Cartwright, E. J. (2020). Targeting Ca<SUP>2+</SUP>Handling Proteins for the Treatment of Heart Failure and Arrhythmias. FRONTIERS IN PHYSIOLOGY, 11. doi:10.3389/fphys.2020.01068
2018
Sphingosine 1-phosphate activation of ERM contributes to vascular calcification
Morris, T. G., Borland, S. J., Clarke, C. J., Wilson, C., Hannun, Y. A., Ohanian, V., . . . Ohanian, J. (2018). Sphingosine 1-phosphate activation of ERM contributes to vascular calcification. JOURNAL OF LIPID RESEARCH, 59(1), 69-78. doi:10.1194/jlr.M079731
2017
Plasma membrane Ca<SUP>2+</SUP>-ATPase 1 is required for maintaining atrial Ca<SUP>2+</SUP> homeostasis and electrophysiological stability in the mouse
Wang, Y., Wilson, C., Cartwright, E. J., & Lei, M. (2017). Plasma membrane Ca<SUP>2+</SUP>-ATPase 1 is required for maintaining atrial Ca<SUP>2+</SUP> homeostasis and electrophysiological stability in the mouse. JOURNAL OF PHYSIOLOGY-LONDON, 595(24), 7383-7398. doi:10.1113/JP274110
[OP.2C.01] THE ROLE OF PMCA1 IN HYPERTENSION AND ARRHYTHMIA SUSCEPTIBILITY IN RELATION TO AGEING
Wilson, C., Little, R., Zi, M., & Cartwright, E. (2017). [OP.2C.01] THE ROLE OF PMCA1 IN HYPERTENSION AND ARRHYTHMIA SUSCEPTIBILITY IN RELATION TO AGEING. Journal of Hypertension, 35(Supplement 2), e18. doi:10.1097/01.hjh.0000523027.68709.46
THE PLASMA MEMBRANE CALCIUM ATPASES AND THEIR ROLE AS MAJOR NEW PLAYERS IN HUMAN DISEASE
Stafford, N., Wilson, C., Oceandy, D., Neyses, L., & Cartwright, E. J. (2017). THE PLASMA MEMBRANE CALCIUM ATPASES AND THEIR ROLE AS MAJOR NEW PLAYERS IN HUMAN DISEASE. PHYSIOLOGICAL REVIEWS, 97(3), 1089-1125. doi:10.1152/physrev.00028.2016
216 Identifying a novel role for pmca1 (atp2b1) in heart rhythm instability
Wilson, C., Cartwright, E., Zi, M., & Li, Y. (2017). 216 Identifying a novel role for pmca1 (atp2b1) in heart rhythm instability. Heart, 103(Suppl 5), A142.1-A142. doi:10.1136/heartjnl-2017-311726.214
2015
11 PMCA1 and arrhythmias: does deletion of PMCA1 lead to heart rhythm instability?
Wilson, C., Zi, M., & Cartwright, E. J. (2015). 11 PMCA1 and arrhythmias: does deletion of PMCA1 lead to heart rhythm instability?. Abstracts, A4.2-A4. doi:10.1136/heartjnl-2015-308734.11
2014
P710Differential regulation of vascular calcification by neutral and acid sphingomyelinases
Morris, T. G., Wilson, C., Ohanian, V., Canfield, A. E., & Ohanian, J. (2014). P710Differential regulation of vascular calcification by neutral and acid sphingomyelinases. Cardiovascular Research, 103(suppl 1), S129.5-S130. doi:10.1093/cvr/cvu098.132