Research outputs
2026
Childhood attention deficit hyperactivity disorder traits, societal exclusion and midlife psychological distress
John, A., O’Nions, E., Corrigan, L., Cotton, J., Donnellan, W. J., Nimmons, D., . . . Stott, J. (2026). Childhood attention deficit hyperactivity disorder traits, societal exclusion and midlife psychological distress. Nature Mental Health. doi:10.1038/s44220-026-00600-0
Autistic traits and suicidality in midlife and old age: investigating mediating effects of mental health and social connectedness
Nuzum, E., Medeisyte, R., Eshetu, A., Hoare, S., Corbett, A., Ballard, C., . . . Stott, J. (2026). Autistic traits and suicidality in midlife and old age: investigating mediating effects of mental health and social connectedness. NATURE MENTAL HEALTH, 4(2). doi:10.1038/s44220-025-00579-0
Symptom change in depression and anxiety during psychological therapy for autistic adults
Pender, R., El Baou, C., O'Nions, E., Spector, A., Buckman, J. E. J., Richards, M., . . . Mandy, W. (2026). Symptom change in depression and anxiety during psychological therapy for autistic adults. NATURE MENTAL HEALTH, 4(2). doi:10.1038/s44220-025-00567-4
Attention-Deficit/Hyperactivity Disorder Traits in Childhood and Physical Health in Midlife
Stott, J., O'Nions, E., Corrigan, L., Cotton, J., Donnellan, W. J., Nimmons, D., . . . John, A. (2026). Attention-Deficit/Hyperactivity Disorder Traits in Childhood and Physical Health in Midlife. JAMA NETWORK OPEN, 9(1). doi:10.1001/jamanetworkopen.2025.54802
2025
Characterising inequalities in accessing primary care psychological therapies services for people living with dementia: the example of NHS talking therapies in England.
El Baou, C., Saunders, R., Buckman, J. E. J., Richards, M., Cooper, C., Marchant, N., . . . Stott, J. (2025). Characterising inequalities in accessing primary care psychological therapies services for people living with dementia: the example of NHS talking therapies in England.. Epidemiology and psychiatric sciences, 34, e60. doi:10.1017/s2045796025100309
A systematic review and thematic synthesis on the experiences of accessing and attending psychological therapy for informal carers of people living with dementia
Yang, J., Fearn, C., John, A., Hoare, S., Chang, S., Zammitt, D., & Stott, J. (2025). A systematic review and thematic synthesis on the experiences of accessing and attending psychological therapy for informal carers of people living with dementia. BMC GERIATRICS, 25(1). doi:10.1186/s12877-025-05986-7
Associations between life satisfaction and hope with cognitive function and decline over 13 years: findings from the Whitehall II study
John, A., Patel, A. M. R., Desai, R., Willroth, E., Marchant, N. L., Demnitz-King, H., . . . Stott, J. (2025). Associations between life satisfaction and hope with cognitive function and decline over 13 years: findings from the Whitehall II study. EUROPEAN JOURNAL OF AGEING, 22(1). doi:10.1007/s10433-025-00892-8
Evidence for Causal Links Between Known Modifiable Risk Factors and Dementia: A Systematic Review of Mendelian Randomisation Studies
Desai, R., John, A., Anderson, E., Stafford, J., Patel, A. M. R., Marchant, N. L., . . . Stott, J. (2025). Evidence for Causal Links Between Known Modifiable Risk Factors and Dementia: A Systematic Review of Mendelian Randomisation Studies. EUROPEAN JOURNAL OF NEUROLOGY, 32(12). doi:10.1111/ene.70458
The Association between Autistic Traits and Trajectories of Anxiety in Middle-Aged and Older Adults: An 8-year Growth Mixture Model Analysis
Better Living with Non-memory-led Dementia: study protocol for a randomised controlled trial of a web-based caregiver educational programme (BELIDE trial).
Suarez-Gonzalez, A., Brotherhood, E., John, A., Hayes, O., Rossi-Harries, S., Zimmermann, N., . . . Stott, J. (2025). Better Living with Non-memory-led Dementia: study protocol for a randomised controlled trial of a web-based caregiver educational programme (BELIDE trial).. BMJ open, 15(9), e102518. doi:10.1136/bmjopen-2025-102518
Effectiveness of psychological interventions for young adults versus working age adults: a retrospective cohort study in a national psychological treatment programme in England
Saunders, R., Suh, J. W., Buckman, J. E. J., John, A., El Baou, C., Pilling, S., . . . Stringaris, A. (2025). Effectiveness of psychological interventions for young adults versus working age adults: a retrospective cohort study in a national psychological treatment programme in England. LANCET PSYCHIATRY, 12(9), 650-659. doi:10.1016/S2215-0366(25)00207-X
Prevalence of Post-Traumatic Stress Disorder (PTSD) in autistic children or young people (CYP) and adults: A systematic review and meta-analysis
Mansour, H., Kurana, S., Eshetu, A., Hoare, S., El Baou, C., Arnold, I., . . . Stott, J. (2025). Prevalence of Post-Traumatic Stress Disorder (PTSD) in autistic children or young people (CYP) and adults: A systematic review and meta-analysis. CLINICAL PSYCHOLOGY REVIEW, 120. doi:10.1016/j.cpr.2025.102621
Understanding Interactions Between Life Satisfaction and Genetic Predisposition on Risk of Alzheimer's Disease up to 14 Years Later: Findings From the UK Biobank
John, A., Desai, R., Bartres-Faz, D., Cadar, D., Gaysina, D., Gonzalez, A. S., . . . Stott, J. (2025). Understanding Interactions Between Life Satisfaction and Genetic Predisposition on Risk of Alzheimer's Disease up to 14 Years Later: Findings From the UK Biobank. INTERNATIONAL JOURNAL OF GERIATRIC PSYCHIATRY, 40(7). doi:10.1002/gps.70120
Risk of suicide in people living with dementia and comorbid mental health conditions: A systematic review and meta-analysis
Medeisyte, R., Nuzum, E., John, A., Tsipa, A., Fearn, C., Charlesworth, G., . . . Desai, R. (2025). Risk of suicide in people living with dementia and comorbid mental health conditions: A systematic review and meta-analysis. JOURNAL OF AFFECTIVE DISORDERS, 379, 835-844. doi:10.1016/j.jad.2025.03.075
A record-linkage study of post-stroke primary care psychological therapy effectiveness in England
Suh, J. W., Bell, V., Buckman, J. E. J., El Baou, C., Desai, R., Fearn, C., . . . Saunders, R. (2025). A record-linkage study of post-stroke primary care psychological therapy effectiveness in England. NATURE MENTAL HEALTH, 3(6). doi:10.1038/s44220-025-00429-z
Life expectancy and years of life lost for adults with diagnosed ADHD in the UK: matched cohort study
O'Nions, E., El Baou, C., John, A., Lewer, D., Mandy, W., Mckechnie, D. G. J., . . . Stott, J. (2025). Life expectancy and years of life lost for adults with diagnosed ADHD in the UK: matched cohort study. BRITISH JOURNAL OF PSYCHIATRY, 226(5), 261-268. doi:10.1192/bjp.2024.199
The Association Between Autism Spectrum Traits and Age-Related Spatial Working Memory Decline: A Large-Scale Longitudinal Study
Ghai, S., Eshetu, A., Corbett, A., Ballard, C., Aarsland, D., Hampshire, A., . . . John, A. (2025). The Association Between Autism Spectrum Traits and Age-Related Spatial Working Memory Decline: A Large-Scale Longitudinal Study. GERONTOLOGIST, 65(5). doi:10.1093/geront/gnaf096
Depression and anxiety symptom change during psychological therapy for autistic clients: Evidence from national healthcare records in England
Dementia subtypes and suicidality: A systematic review and meta-analysis
Nuzum, E., Medeisyte, R., Desai, R., Tsipa, A., Fearn, C., Eshetu, A., . . . John, A. (2025). Dementia subtypes and suicidality: A systematic review and meta-analysis. NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS, 169. doi:10.1016/j.neubiorev.2024.105995
Bidirectional changes in depressive symptoms and social functioning in older adults attending psychological therapy services
Steare, T., Buckman, J. E. J., Stott, J., John, A., Singh, S., Wheatley, J., . . . Saunders, R. (2025). Bidirectional changes in depressive symptoms and social functioning in older adults attending psychological therapy services. JOURNAL OF AFFECTIVE DISORDERS, 369, 954-962. doi:10.1016/j.jad.2024.10.098
Effectiveness of psychological therapies for depression or anxiety in adults with intellectual disabilities: retrospective, matched, observational cohort study of primary care electronic healthcare records in England
El Baou, C., Saunders, R., Buckman, J. E. J., Dagnan, D., Mandy, W., O'Nions, E., . . . Stott, J. (2025). Effectiveness of psychological therapies for depression or anxiety in adults with intellectual disabilities: retrospective, matched, observational cohort study of primary care electronic healthcare records in England. BRITISH JOURNAL OF PSYCHIATRY. doi:10.1192/bjp.2025.127
The Association between Autistic Traits and Trajectories of Anxiety in Middle-Aged and Older Adults: An 8-Year Growth Mixture Model Analysis
The Experience of People With Dementia in Accessing and Engaging in Talking Therapies for Mental Health Difficulties: A Systematic Review and Thematic Meta-Synthesis.
Zammitt, D., Fearn, C., John, A., Lykourgos, M., Kurana, S., Hayes, O., & Stott, J. (2025). The Experience of People With Dementia in Accessing and Engaging in Talking Therapies for Mental Health Difficulties: A Systematic Review and Thematic Meta-Synthesis.. Dementia (London, England), 14713012251408694. doi:10.1177/14713012251408694
Wellbeing and memory function: testing bidirectional associations in the English Longitudinal Study of Ageing (ELSA)
John, A., Desai, R., Eshetu, A., Willroth, E., Marchant, N., Woodward-Carlton, B., . . . Stott, J. (2025). Wellbeing and memory function: testing bidirectional associations in the English Longitudinal Study of Ageing (ELSA). AGING & MENTAL HEALTH, 29(10), 1807-1813. doi:10.1080/13607863.2025.2468408
2024
Effectiveness of psychological therapies for depression and anxiety in atypical dementia
El Baou, C., Saunders, R., Buckman, J. E. J., Richards, M., Cooper, C., Marchant, N. L., . . . Stott, J. (2024). Effectiveness of psychological therapies for depression and anxiety in atypical dementia. ALZHEIMERS & DEMENTIA, 20(12), 8844-8854. doi:10.1002/alz.14332
Real-world effectiveness of primary care psychological therapy for depression and anxiety in patients with coronary heart disease
Suh, J., Baou, C. E., John, A., Stott, J., & Saunders, R. (2024). Real-world effectiveness of primary care psychological therapy for depression and anxiety in patients with coronary heart disease. EUROPEAN HEART JOURNAL, 45. doi:10.1093/eurheartj/ehae666.3027
Suicide and dementia: A systematic review and meta-analysis of prevalence and risk factors
Desai, R., Tsipa, A., Fearn, C., El Baou, C., Brotherhood, E. V., Charlesworth, G., . . . John, A. (2024). Suicide and dementia: A systematic review and meta-analysis of prevalence and risk factors. AGEING RESEARCH REVIEWS, 100. doi:10.1016/j.arr.2024.102445
Evidence for causal links between known modifiable risk factors and dementia: A systematic review of Mendelian randomization studies
A review of the literature on wellbeing and modifiable dementia risk factors
Willroth, E. C., Pfund, G. N., Rule, P. D., Hill, P. L., John, A., Kyle, K., . . . James, B. D. (2024). A review of the literature on wellbeing and modifiable dementia risk factors. AGEING RESEARCH REVIEWS, 99. doi:10.1016/j.arr.2024.102380
Bidirectional Associations of Depressive Symptoms and Cognitive Function Over Time
Yin, J., John, A., & Cadar, D. (2024). Bidirectional Associations of Depressive Symptoms and Cognitive Function Over Time. JAMA NETWORK OPEN, 7(6). doi:10.1001/jamanetworkopen.2024.16305
Predictors of primary care psychological therapy outcomes for depression and anxiety in people living with dementia: evidence from national healthcare records in England
Bell, G., El Baou, C., Saunders, R., Buckman, J. E. J., Charlesworth, G., Richards, M., . . . Stott, J. (2024). Predictors of primary care psychological therapy outcomes for depression and anxiety in people living with dementia: evidence from national healthcare records in England. BRITISH JOURNAL OF PSYCHIATRY, 224(6), 205-212. doi:10.1192/bjp.2024.12
Effectiveness of Cognitive Stimulation Therapy (CST) for mild to moderate dementia: A systematic literature review and meta-analysis of randomised control trials using the original CST protocol
Desai, R., Leung, W. G., Fearn, C., John, A., Stott, J., & Spector, A. (2024). Effectiveness of Cognitive Stimulation Therapy (CST) for mild to moderate dementia: A systematic literature review and meta-analysis of randomised control trials using the original CST protocol. AGEING RESEARCH REVIEWS, 97. doi:10.1016/j.arr.2024.102312
Measurement invariance and differential item functioning of the PHQ-9 and GAD-7 between working age and older adults seeking treatment for common mental disorders
Delamain, H., Buckman, J. E. J., Stott, J., John, A., Singh, S., Pilling, S., & Saunders, R. (2024). Measurement invariance and differential item functioning of the PHQ-9 and GAD-7 between working age and older adults seeking treatment for common mental disorders. JOURNAL OF AFFECTIVE DISORDERS, 347, 15-22. doi:10.1016/j.jad.2023.11.048
2023
"Better Living with Non-memory-led Dementia": protocol for a feasibility randomised controlled trial of a web-based caregiver educational programme
Suarez-Gonzalez, A., John, A., Brotherhood, E., Camic, P. M., McKee-Jackson, R., Melville, M., . . . Rare, D. S. I. T. (2023). "Better Living with Non-memory-led Dementia": protocol for a feasibility randomised controlled trial of a web-based caregiver educational programme. PILOT AND FEASIBILITY STUDIES, 9(1). doi:10.1186/s40814-023-01403-1
Better living with non‐memory led dementia: results from a pilot randomised clinical trial of an online training programme for carers of people with PCA, PPA and bvFTD
Gonzalez, A., John, A., Brotherhood, E. V., Camic, P., McKee‐Jackson, R., Melville, M., . . . Impact, R. D. S. (2023). Better living with non‐memory led dementia: results from a pilot randomised clinical trial of an online training programme for carers of people with PCA, PPA and bvFTD. Poster session presented at the meeting of Unknown Conference. doi:10.1002/alz.075329
Effectiveness of primary care psychological therapy services for treating depression and anxiety in autistic adults in England: a retrospective, matched, observational cohort study of national health-care records
El Baou, C., Bell, G., Saunders, R., Buckman, J. E. J., Mandy, W., Dagnan, D., . . . Stott, J. (2023). Effectiveness of primary care psychological therapy services for treating depression and anxiety in autistic adults in England: a retrospective, matched, observational cohort study of national health-care records. LANCET PSYCHIATRY, 10(12), 944-954. doi:10.1016/S2215-0366(23)00291-2
Examining the Lancet Commission risk factors for dementia using Mendelian randomisation
Desai, R., John, A., Saunders, R., Marchant, N. L., Buckman, J. E. J., Charlesworth, G., . . . Stott, J. (2023). Examining the Lancet Commission risk factors for dementia using Mendelian randomisation. BMJ MENTAL HEALTH, 26(1). doi:10.1136/bmjment-2022-300555
Associations between psychological therapy outcomes for depression and incidence of dementia
John, A., Saunders, R., Desai, R., Bell, G., Fearn, C., Buckman, J. E. J., . . . Stott, J. (2023). Associations between psychological therapy outcomes for depression and incidence of dementia. PSYCHOLOGICAL MEDICINE, 53(11), 4869-4879. doi:10.1017/S0033291722002537
Psychological therapies for depression and cardiovascular risk: evidence from national healthcare records in England
El Baou, C., Desai, R., Cooper, C., Marchant, N. L., Pilling, S., Richards, M., . . . Stott, J. (2023). Psychological therapies for depression and cardiovascular risk: evidence from national healthcare records in England. EUROPEAN HEART JOURNAL, 44(18). doi:10.1093/eurheartj/ehad188
Associations between psychological intervention for anxiety disorders and risk of dementia: a prospective cohort study using national health-care records data in England
Stott, J., Saunders, R., Desai, R., Bell, G., Fearn, C., Buckman, J. E. J., . . . John, A. (2023). Associations between psychological intervention for anxiety disorders and risk of dementia: a prospective cohort study using national health-care records data in England. LANCET HEALTHY LONGEVITY, 4(1), e12-e22. doi:10.1016/S2666-7568(22)00242-2
Suicide and Dementia: A Systematic Review and Meta-Analysis of Prevalence and Risk Factors
2022
Positive psychological constructs and cognitive function: A systematic review and meta-analysis
Bell, G., Singham, T., Saunders, R., Buckman, J. E. J., Charlesworth, G., Richards, M., . . . Stott, J. (2022). Positive psychological constructs and cognitive function: A systematic review and meta-analysis. AGEING RESEARCH REVIEWS, 82. doi:10.1016/j.arr.2022.101745
Effectiveness of primary care psychological therapy services for the treatment of depression and anxiety in people living with dementia: Evidence from national healthcare records in England
Bell, G., El Baou, C., Saunders, R., Buckman, J. E. J., Charlesworth, G., Richards, M., . . . Stott, J. (2022). Effectiveness of primary care psychological therapy services for the treatment of depression and anxiety in people living with dementia: Evidence from national healthcare records in England. ECLINICALMEDICINE, 52. doi:10.1016/j.eclinm.2022.101692
Salivary cortisol in longitudinal associations between affective symptoms and midlife cognitive function: A British birth cohort study
John, A., Desai, R., Saunders, R., Buckman, J. E. J., Brown, B., Nurock, S., . . . Stott, J. (2022). Salivary cortisol in longitudinal associations between affective symptoms and midlife cognitive function: A British birth cohort study. JOURNAL OF PSYCHIATRIC RESEARCH, 151, 217-224. doi:10.1016/j.jpsychires.2022.04.007
Positive psychological constructs and association with reduced risk of mild cognitive impairment and dementia in older adults: A systematic review and meta-analysis
Bell, G., Singham, T., Saunders, R., John, A., & Stott, J. (2022). Positive psychological constructs and association with reduced risk of mild cognitive impairment and dementia in older adults: A systematic review and meta-analysis. AGEING RESEARCH REVIEWS, 77. doi:10.1016/j.arr.2022.101594
Childhood reading problems and cognitive ageing across mid to later life
John, A., Stott, J., & Richards, M. (2022). Childhood reading problems and cognitive ageing across mid to later life. JOURNAL OF EPIDEMIOLOGY AND COMMUNITY HEALTH, 76(1), 67-74. doi:10.1136/jech-2020-215735
2021
Childhood neglect and trajectories of affective symptoms throughout adulthood: A British birth cohort study
Rozanski, S., Schmidt, A., John, A., & Gaysina, D. (2021). Childhood neglect and trajectories of affective symptoms throughout adulthood: A British birth cohort study. JOURNAL OF AFFECTIVE DISORDERS, 295, 416-421. doi:10.1016/j.jad.2021.08.021
Affective symptoms and risk of progression to mild cognitive impairment or dementia in subjective cognitive decline: A systematic review and meta-analysis
Desai, R., Whitfield, T., Said, G., John, A., Saunders, R., Marchant, N. L., . . . Charlesworth, G. (2021). Affective symptoms and risk of progression to mild cognitive impairment or dementia in subjective cognitive decline: A systematic review and meta-analysis. AGEING RESEARCH REVIEWS, 71. doi:10.1016/j.arr.2021.101419
Older adults respond better to psychological therapy than working-age adults: evidence from a large sample of mental health service attendees.
Saunders, R., Buckman, J. E. J., Stott, J., Leibowitz, J., Aguirre, E., John, A., . . . Pilling, S. (2021). Older adults respond better to psychological therapy than working-age adults: evidence from a large sample of mental health service attendees.. JOURNAL OF AFFECTIVE DISORDERS, 294, 85-93. doi:10.1016/j.jad.2021.06.084
Neuropsychological deficits in Posterior Cortical Atrophy and typical Alzheimer's disease: A meta-analytic review
North, C., Desai, R., Saunders, R., Suarez-Gonzalez, A., Bamiou, D., Costafreda, S. G., . . . Stott, J. (2021). Neuropsychological deficits in Posterior Cortical Atrophy and typical Alzheimer's disease: A meta-analytic review. CORTEX, 143, 223-236. doi:10.1016/j.cortex.2021.07.011
Role of cardiometabolic risk in the association between accumulation of affective symptoms across adulthood and mid-life cognitive function: national cohort study
John, A., Desai, R., Richards, M., Gaysina, D., & Stott, J. (2021). Role of cardiometabolic risk in the association between accumulation of affective symptoms across adulthood and mid-life cognitive function: national cohort study. BRITISH JOURNAL OF PSYCHIATRY, 218(5), 254-260. doi:10.1192/bjp.2020.123
Associations between childhood reading problems and affective symptoms across the life course: Evidence from the 1946 British Birth Cohort
John, A., Stott, J., & Richards, M. (2021). Associations between childhood reading problems and affective symptoms across the life course: Evidence from the 1946 British Birth Cohort. JOURNAL OF AFFECTIVE DISORDERS, 282, 284-288. doi:10.1016/j.jad.2020.12.054
Bidirectional relation between affective symptoms and cognitive function from middle to late adulthood: a population-based birth cohort study
John, A., Rusted, J., Richards, M., & Gaysina, D. (2021). Bidirectional relation between affective symptoms and cognitive function from middle to late adulthood: a population-based birth cohort study. AGING & MENTAL HEALTH, 25(9), 1642-1648. doi:10.1080/13607863.2020.1758916
2020
Living alone and risk of dementia: A systematic review and meta-analysis
Desai, R., John, A., Stott, J., & Charlesworth, G. (2020). Living alone and risk of dementia: A systematic review and meta-analysis. AGEING RESEARCH REVIEWS, 62. doi:10.1016/j.arr.2020.101122
Affective symptoms across the life course and resilience in cognitive function
Bell, G., John, A., & Gaysina, D. (2020). Affective symptoms across the life course and resilience in cognitive function. ANNALS OF HUMAN BIOLOGY, 47(2), 116-124. doi:10.1080/03014460.2020.1745886
Accumulation of affective symptoms and midlife cognitive function: The role of inflammation
John, A., Rusted, J., Richards, M., & Gaysina, D. (2020). Accumulation of affective symptoms and midlife cognitive function: The role of inflammation. BRAIN BEHAVIOR AND IMMUNITY, 84, 164-172. doi:10.1016/j.bbi.2019.11.021
2019
Effects of affective symptoms in adolescence and adulthood on trajectories of cognitive function from middle to late adulthood
John, A., James, S. -N., Rusted, J., Richards, M., & Gaysina, D. (2019). Effects of affective symptoms in adolescence and adulthood on trajectories of cognitive function from middle to late adulthood. JOURNAL OF AFFECTIVE DISORDERS, 259, 424-431. doi:10.1016/j.jad.2019.08.077
Longitudinal associations of affective symptoms with mid-life cognitive function: evidence from a British birth cohort
John, A., James, S. -N., Patel, U., Rusted, J., Richards, M., & Gaysina, D. (2019). Longitudinal associations of affective symptoms with mid-life cognitive function: evidence from a British birth cohort. BRITISH JOURNAL OF PSYCHIATRY, 215(5), 675-682. doi:10.1192/bjp.2019.24
Affective problems and decline in cognitive state in older adults: a systematic review and meta-analysis
John, A., Patel, U., Rusted, J., Richards, M., & Gaysina, D. (2019). Affective problems and decline in cognitive state in older adults: a systematic review and meta-analysis. PSYCHOLOGICAL MEDICINE, 49(3), 353-365. doi:10.1017/S0033291718001137
2018
Lifetime affective problems and later-life cognitive state: Over 50 years of follow-up in a British birth cohort study
James, S. -N., Davis, D., O'Hare, C., Sharma, N., John, A., Gaysina, D., . . . Richards, M. (2018). Lifetime affective problems and later-life cognitive state: Over 50 years of follow-up in a British birth cohort study. JOURNAL OF AFFECTIVE DISORDERS, 241, 348-355. doi:10.1016/j.jad.2018.07.078