Photo of Dr Andrew Chetwynd

Dr Andrew Chetwynd

Women's & Children's Health


Personal Statement

My scientific career started at the University of Surrey where I studied for a BSc in Biochemistry (Toxicology) during which time I carried out a placement year at GSK. While at GSK I was introduced to analytical chemistry, in particular liquid chromatography and mass spectrometry for the characterisation of pharmaceuticals and their metabolites. Upon completing my BSc I moved to the University of Sussex for a PhD with Professor Liz Hill and Dr Alaa Abdul Sada where I developed nanoLC-nanoESI-ToF-MS methods for improved sensitivity in urinary metabolomics. Here I worked on urinary normalisation methods and nanoLC-MS methods which I then applied to investigate renal toxicity associated with HIV. During a short post-doctoral position at Sussex in the same lab I modified these methods for work on faecal samples to investigate colorectal cancer.
I then moved to the University of Birmingham to work in a high throughput clinical and environmental metabolomics facility. After 18 months I changed fields to materials chemistry and undertook a 2 year Horizon 2020 indutry post doc position with Sciex developing capillary electrophoresis-mass spectrometry methods to characterise proteins and metabolites involved in bio-nano interactions. I then returned to the University of Birmingham to continue this Horizon 2020 project working on bio-nano interactions and the characterisation of nanoparticles using ICP-MS and single particle ICP-MS in addition to microplastics using thermogravimetric analysis- Fourier Transform Infrared spectroscopy -gas chromatography-mass spectrometry (TGA-FTIR-GC-MS)
In 2021 I moved to the University of Liverpool to work with Dr Louise Oni at The Institute in the Park based at the Alder Hey Children’s Hospital and Professor Claire Eyers at CPR on a Kidney Research UK grant investigating glycosylation of IgA in childhood IgA vasculitis and associated nephropathy.