Dr Xuan Liu

Biochemistry & Systems Biology

Publications

2021

Assessment of the impact of mitochondrial genotype upon drug-induced mitochondrial dysfunction in platelets derived from healthy volunteers (Journal article)

Ball, A. L., Bloch, K. M., Rainbow, L., Liu, X., Kenny, J., Lyon, J. J., . . . Chadwick, A. E. (n.d.). Assessment of the impact of mitochondrial genotype upon drug-induced mitochondrial dysfunction in platelets derived from healthy volunteers. Archives of Toxicology. doi:10.1007/s00204-021-02988-3

DOI: 10.1007/s00204-021-02988-3

2020

Small Non-Coding RNAome of Ageing Chondrocytes (Journal article)

Balaskas, P., Green, J. A., Haqqi, T. M., Dyer, P., Kharaz, Y. A., Fang, Y., . . . Peffers, M. J. (2020). Small Non-Coding RNAome of Ageing Chondrocytes. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 21(16). doi:10.3390/ijms21165675

DOI: 10.3390/ijms21165675

Targeted Next-Generation Sequencing of 117 Routine Clinical Samples Provides Further Insights into the Molecular Landscape of Uveal Melanoma (Journal article)

Thornton, S., Coupland, S. E., Olohan, L., Sibbring, J. S., Kenny, J. G., Hertz-Fowler, C., . . . Kalirai, H. (2020). Targeted Next-Generation Sequencing of 117 Routine Clinical Samples Provides Further Insights into the Molecular Landscape of Uveal Melanoma. CANCERS, 12(4). doi:10.3390/cancers12041039

DOI: 10.3390/cancers12041039

Whole-Genome Sequence of Streptomyces kaniharaensis Shomura and Niida SF-557. (Journal article)

Zhu, W., Liu, X., Hughes, M., de Crécy-Lagard, V., & Richards, N. G. J. (2020). Whole-Genome Sequence of Streptomyces kaniharaensis Shomura and Niida SF-557.. Microbiology Resource Announcements, 9(14). doi:10.1128/mra.01434-19

DOI: 10.1128/mra.01434-19

Field cricket genome reveals the footprint of recent, abrupt adaptation in the wild (Journal article)

Pascoal, S., Risse, J. E., Zhang, X., Blaxter, M., Cezard, T., Challis, R. J., . . . Bailey, N. W. (2020). Field cricket genome reveals the footprint of recent, abrupt adaptation in the wild. EVOLUTION LETTERS, 4(1), 19-33. doi:10.1002/evl3.148

DOI: 10.1002/evl3.148

2019

Fluconazole Monotherapy Is a Suboptimal Option for Initial Treatment of Cryptococcal Meningitis Because of Emergence of Resistance. (Journal article)

Hope, W., Stone, N. R. H., Johnson, A., McEntee, L., Farrington, N., Santoro-Castelazo, A., . . . Bicanic, T. (2019). Fluconazole Monotherapy Is a Suboptimal Option for Initial Treatment of Cryptococcal Meningitis Because of Emergence of Resistance.. mBio, 10(6). doi:10.1128/mbio.02575-19

DOI: 10.1128/mbio.02575-19

Investigating the Cellular Transcriptomic Response Induced by the Makona Variant of Ebola Virus in Differentiated THP-1 Cells (Journal article)

Bosworth, A., Dowall, S. D., Armstrong, S., Liu, X., Dong, X., Bruce, C. B., . . . Hiscox, J. A. (2019). Investigating the Cellular Transcriptomic Response Induced by the Makona Variant of Ebola Virus in Differentiated THP-1 Cells. VIRUSES-BASEL, 11(11). doi:10.3390/v11111023

DOI: 10.3390/v11111023

Immunological observations and transcriptomic analysis of trimester-specific full-term placentas from three Zika virus-infected women (Journal article)

Lum, F. -M., Narang, V., Hue, S., Chen, J., McGovern, N., Rajarethinam, R., . . . Ng, L. F. P. (n.d.). Immunological observations and transcriptomic analysis of trimester-specific full-term placentas from three Zika virus-infected women. Clinical and Translational Immunology, 8(11). doi:10.1002/cti2.1082

DOI: 10.1002/cti2.1082

2018

Oral iron exacerbates colitis and influences the intestinal microbiome (Journal article)

Mahalhal, A., Williams, J. M., Johnson, S., Ellaby, N., Duckworth, C. A., Burkitt, M. D., . . . Probert, C. S. (2018). Oral iron exacerbates colitis and influences the intestinal microbiome. PLOS ONE, 13(10). doi:10.1371/journal.pone.0202460

DOI: 10.1371/journal.pone.0202460

Temperature Driven Changes in Benthic Bacterial Diversity Influences Biogeochemical Cycling in Coastal Sediments (Journal article)

Hicks, N., Liu, X., Gregory, R., Kenny, J., Lucaci, A., Lenzi, L., . . . Duncan, K. R. (2018). Temperature Driven Changes in Benthic Bacterial Diversity Influences Biogeochemical Cycling in Coastal Sediments. FRONTIERS IN MICROBIOLOGY, 9. doi:10.3389/fmicb.2018.01730

DOI: 10.3389/fmicb.2018.01730

Genomics of habitat choice and adaptive evolution in a deep-sea fish (Journal article)

Gaither, M. R., Gkafas, G. A., de Jong, M., Sarigol, F., Neat, F., Regnier, T., . . . Hoelzel, A. R. (2018). Genomics of habitat choice and adaptive evolution in a deep-sea fish. NATURE ECOLOGY & EVOLUTION, 2(4), 680-687. doi:10.1038/s41559-018-0482-x

DOI: 10.1038/s41559-018-0482-x

Zika Virus Infection Preferentially Counterbalances Human Peripheral Monocyte and/or NK Cell Activity (Journal article)

Lum, F. -M., Lee, D., Chua, T. -K., Tan, J. J. L., Lee, C. Y. P., Liu, X., . . . Ng, L. F. P. (2018). Zika Virus Infection Preferentially Counterbalances Human Peripheral Monocyte and/or NK Cell Activity. MSPHERE, 3(2), 18 pages. doi:10.1128/mSphereDirect.00120-18

DOI: 10.1128/mSphereDirect.00120-18

Increased socially mediated plasticity in gene expression accompanies rapid adaptive evolution (Journal article)

Pascoal, S., Liu, X., Fang, Y., Paterson, S., Ritchie, M. G., Rockliffe, N., . . . Bailey, N. W. (2018). Increased socially mediated plasticity in gene expression accompanies rapid adaptive evolution. Ecology Letters, 21(4), 546-556. doi:10.1111/ele.12920

DOI: 10.1111/ele.12920

2017

Deep Sequencing of RNA from Blood and Oral Swab Samples Reveals the Presence of Nucleic Acid from a Number of Pathogens in Patients with Acute Ebola Virus Disease and Is Consistent with Bacterial Translocation across the Gut (Journal article)

Carroll, M. W., Haldenby, S., Rickett, N. Y., Palyi, B., Garcia-Dorival, I., Liu, X., . . . Hiscox, J. A. (2017). Deep Sequencing of RNA from Blood and Oral Swab Samples Reveals the Presence of Nucleic Acid from a Number of Pathogens in Patients with Acute Ebola Virus Disease and Is Consistent with Bacterial Translocation across the Gut. MSPHERE, 2(04), 19 pages. doi:10.1128/mSphereDirect.00325-17

DOI: 10.1128/mSphereDirect.00325-17

Deep sequencing of RNA from blood and oral swab samples reveals the presence of nucleic acid from a number of pathogens in patients with acute Ebola virus disease and is consistent with bacterial translocation across the gut (Journal article)

Carroll, M. W., Haldenby, S., Rickett, N. Y., Pályi, B., Garcia-Dorival, I., Liu, X., . . . Hiscox, J. A. (2017). Deep sequencing of RNA from blood and oral swab samples reveals the presence of nucleic acid from a number of pathogens in patients with acute Ebola virus disease and is consistent with bacterial translocation across the gut. mSphere, 2(4). doi:10.1128/mSphereDirect.00325-17

DOI: 10.1128/mSphereDirect.00325-17

Transcriptomic signatures differentiate survival from fatal outcomes in humans infected with Ebola virus (Journal article)

Liu, X., Speranza, E., Muñoz-Fontela, C., Haldenby, S., Rickett, N., Garcia-Dorival, I., . . . Hiscox, J. (2017). Transcriptomic signatures differentiate survival from fatal outcomes in humans infected with Ebola virus. Genome Biology, 18. doi:10.1186/s13059-016-1137-3

DOI: 10.1186/s13059-016-1137-3

2016

Analysis of transcriptional response to heat stress in Rhazya stricta (Journal article)

Obaid, A. Y., Sabir, J. S. M., Atef, A., Liu, X., Edris, S., El-Domyati, F. M., . . . Jansen, R. K. (2016). Analysis of transcriptional response to heat stress in Rhazya stricta. BMC PLANT BIOLOGY, 16. doi:10.1186/s12870-016-0938-6

DOI: 10.1186/s12870-016-0938-6

A barrier to homologous recombination between sympatric strains of the cooperative soil bacterium Myxococcus xanthus (Journal article)

Wielgoss, S., Didelot, X., Chaudhuri, R. R., Liu, X., Weedall, G. D., Velicer, G. J., & Vos, M. (2016). A barrier to homologous recombination between sympatric strains of the cooperative soil bacterium Myxococcus xanthus. ISME JOURNAL, 10(10), 2468-2477. doi:10.1038/ismej.2016.34

DOI: 10.1038/ismej.2016.34

Local adaptation of a bacterium is as important as its presence in structuring a natural microbial community (Journal article)

Gomez, P., Paterson, S., De Meester, L., Liu, X., Lenzi, L., Sharma, M. D., . . . Buckling, A. (2016). Local adaptation of a bacterium is as important as its presence in structuring a natural microbial community. Nature Communications, 7. doi:10.1038/ncomms12453

DOI: 10.1038/ncomms12453

Rapid evolution and gene expression: a rapidly evolving Mendelian trait that silences field crickets has widespread effects on mRNA and protein expression (Journal article)

Pascoal, S., Liu, X., Ly, T., Fang, Y., Rockliffe, N., Paterson, S., . . . Bailey, N. W. (2016). Rapid evolution and gene expression: a rapidly evolving Mendelian trait that silences field crickets has widespread effects on mRNA and protein expression. JOURNAL OF EVOLUTIONARY BIOLOGY, 29(6), 1234-1246. doi:10.1111/jeb.12865

DOI: 10.1111/jeb.12865

Copper toxicosis in non-COMMD1 Bedlington terriers is associated with metal transport gene ABCA12 (Journal article)

Haywood, S., Boursnell, M., Loughran, M. J., Trafford, J., Isherwood, D., Liu, X., . . . Carter, S. D. (2016). Copper toxicosis in non-COMMD1 Bedlington terriers is associated with metal transport gene ABCA12. JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY, 35, 83-89. doi:10.1016/j.jtemb.2016.01.015

DOI: 10.1016/j.jtemb.2016.01.015

Revised Genome Sequence of the Purple Photosynthetic Bacterium Blastochloris viridis. (Journal article)

Liu, L. -N., Faulkner, M., Liu, X., Huang, F., Darby, A. C., & Hall, N. (2016). Revised Genome Sequence of the Purple Photosynthetic Bacterium Blastochloris viridis.. Genome announcements, 4(1). doi:10.1128/genomea.01520-15

DOI: 10.1128/genomea.01520-15

2015

Transcriptomic Analysis of Shiga-Toxigenic Bacteriophage Carriage Reveals a Profound Regulatory Effect on Acid Resistance in Escherichia coli (Journal article)

Veses-Garcia, M., Liu, X., Rigden, D. J., Kenny, J. G., McCarthy, A. J., & Allison, H. E. (2015). Transcriptomic Analysis of Shiga-Toxigenic Bacteriophage Carriage Reveals a Profound Regulatory Effect on Acid Resistance in Escherichia coli. Applied and Environmental Microbiology, 81(23), 8118-8125. doi:10.1128/AEM.02034-15

DOI: 10.1128/AEM.02034-15

2014

Speeding up systems biology simulations of biochemical pathways using condor (Journal article)

Liu, X., Taylor, S. J. E., Mustafee, N., Wang, J., Gao, Q., & Gilbert, D. (2014). Speeding up systems biology simulations of biochemical pathways using condor. CONCURRENCY AND COMPUTATION-PRACTICE & EXPERIENCE, 26(17), 2727-2742. doi:10.1002/cpe.3161

DOI: 10.1002/cpe.3161

Transcriptomic profiling of cartilage ageing. (Journal article)

Peffers, M. J., Liu, X., & Clegg, P. D. (2014). Transcriptomic profiling of cartilage ageing.. Genomics data, 2, 27-28. doi:10.1016/j.gdata.2014.03.001

DOI: 10.1016/j.gdata.2014.03.001

2013

Transcriptomic signatures in cartilage ageing (Journal article)

Peffers, M. J., Liu, X., & Clegg, P. D. (2013). Transcriptomic signatures in cartilage ageing. ARTHRITIS RESEARCH & THERAPY, 15(4). doi:10.1186/ar4278

DOI: 10.1186/ar4278

TRANSCRIPTOME-WIDE EXPRESSION VARIATION ASSOCIATED WITH ENVIRONMENTAL PLASTICITY AND MATING SUCCESS IN CACTOPHILIC DROSOPHILA MOJAVENSIS (Journal article)

Smith, G., Fang, Y., Liu, X., Kenny, J., Cossins, A. R., de Oliveira, C. C., . . . Ritchie, M. G. (2013). TRANSCRIPTOME-WIDE EXPRESSION VARIATION ASSOCIATED WITH ENVIRONMENTAL PLASTICITY AND MATING SUCCESS IN CACTOPHILIC DROSOPHILA MOJAVENSIS. EVOLUTION, 67(7), 1950-1963. doi:10.1111/evo.12082

DOI: 10.1111/evo.12082

Transcriptomic signatures in cartilage ageing (Journal article)

Peffers, M., Liu, X., & Clegg, P. (2013). Transcriptomic signatures in cartilage ageing. Arthritis Research & Therapy, 15(4), R98. doi:10.1186/ar4278

DOI: 10.1186/ar4278

2012

From a Single Whole Exome Read to Notions of Clinical Screening: Primary Ciliary Dyskinesia and RSPH9 p.Lys268del in the Arabian Peninsula (Journal article)

AlSaadi, M. M., Gaunt, T. R., Boustred, C. R., Guthrie, P. A. I., Liu, X., Lenzi, L., . . . Day, I. N. M. (2012). From a Single Whole Exome Read to Notions of Clinical Screening: Primary Ciliary Dyskinesia and RSPH9 p.Lys268del in the Arabian Peninsula. ANNALS OF HUMAN GENETICS, 76, 211-220. doi:10.1111/j.1469-1809.2012.00704.x

DOI: 10.1111/j.1469-1809.2012.00704.x

From a single whole exome read to notions of clinical screening: primary ciliary dyskinesia and RSPH9 p.Lys268del in the Arabian Peninsula (Journal article)

Alsaadi, M. M., Gaunt, T. R., Boustred, C. R., Guthrie, P. A., Liu, X., Lenzi, L., . . . Day, I. N. (2012). From a single whole exome read to notions of clinical screening: primary ciliary dyskinesia and RSPH9 p.Lys268del in the Arabian Peninsula. Annals of Human Genetics, 76(3), 211-220.