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Research outputs

Selected research outputs

  1. Integrated Analysis of Patient Networks and Plasmid Genomes to Investigate a Regional, Multispecies Outbreak of Carbapenemase-Producing Enterobacterales Carrying Both blaIMP and mcr-9 Genes. (Journal article - 2024)
  2. Whole-genome sequencing reveals widespread presence of<i> Staphylococcus</i><i> capitis</i> NRCS-A clone in neonatal units across the United Kingdom (Journal article - 2023)
  3. IS1-related large- scale deletion of chromosomal regions harbouring the oxygen- insensitive nitroreductase gene<i> nfsB</i> causes nitrofurantoin heteroresistance in<i> Escherichia</i><i> coli</i> (Journal article - 2023)
  4. Alterations in chromosomal genes <i>nfsA, nfsB,</i> and <i>ribE</i> are associated with nitrofurantoin resistance in <i>Escherichia coli</i> from the United Kingdom (Journal article - 2021)
  5. GeneMates: an R package for detecting horizontal gene co-transfer between bacteria using gene-gene associations controlled for population structure (Journal article - 2020)
  6. Complete genome assemblies and antibiograms of 22 <i>Staphylococcus capitis</i> isolates (Journal article - 2025)
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2025

Genomic and molecular characterisation of a KPC-producing Klebsiella pneumoniae clinical isolate resistant to meropenem-vaborbactam, imipenem-relebactam, and ceftazidime-avibactam

DOI
10.21203/rs.3.rs-8289965/v1
Preprint

Two concurrent nationwide healthcare-associated outbreaks of <i>Burkholderia cepacia</i> complex linked to product contamination, UK and Ireland, 2010-2023 (vol. 46, pg. 1006, 2025)

Doran, J., Foster, C., Saunders, M., Chandra, N. L., Turton, J. F., Kenna, D. T. D., . . . Elston, J. W. T. (2025). Two concurrent nationwide healthcare-associated outbreaks of <i>Burkholderia cepacia</i> complex linked to product contamination, UK and Ireland, 2010-2023 (vol. 46, pg. 1006, 2025). INFECTION CONTROL & HOSPITAL EPIDEMIOLOGY, 46(12), 1291. doi:10.1017/ice.2025.10363

DOI
10.1017/ice.2025.10363
Journal article

Two concurrent nationwide healthcare-associated outbreaks of <i>Burkholderia cepacia</i> complex linked to product contamination, UK and Ireland, 2010-2023

Doran, J., Foster, C., Saunders, M., Chandra, N. L., Turton, J. F., Kenna, D. T. D., . . . Elston, J. W. T. (2025). Two concurrent nationwide healthcare-associated outbreaks of <i>Burkholderia cepacia</i> complex linked to product contamination, UK and Ireland, 2010-2023. INFECTION CONTROL & HOSPITAL EPIDEMIOLOGY, 46(10), 1006-1012. doi:10.1017/ice.2025.10232

DOI
10.1017/ice.2025.10232
Journal article

Reviewer response for version 1

Wan, Y. (2025). Reviewer response for version 1. Microbiology Society. doi:10.1099/acmi.0.001025.v1.2

DOI
10.1099/acmi.0.001025.v1.2
Report

Neonatal intensive care units as a driver and reservoir of invasive infections: an example of the emerging Staphylococcus capitis multidrug-resistant NRCS-A clone

Wan, Y., Jauneikaite, E., Gao, L., Pichon, B., Moore, G., Brown, C. S., . . . Ready, D. (2025). Neonatal intensive care units as a driver and reservoir of invasive infections: an example of the emerging Staphylococcus capitis multidrug-resistant NRCS-A clone. INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES, 152. doi:10.1016/j.ijid.2024.107674

DOI
10.1016/j.ijid.2024.107674
Journal article

Understanding the genomic landscape of Klebsiella pneumoniae: insights into bacteraemia across North-West London hospitals between April 2020-December 2021

Rodgus, J., Getino, M., Wan, Y., Davies, F., Holmes, A., & Jauneikaite, E. (2025). Understanding the genomic landscape of Klebsiella pneumoniae: insights into bacteraemia across North-West London hospitals between April 2020-December 2021. INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES, 152. doi:10.1016/j.ijid.2024.107754

DOI
10.1016/j.ijid.2024.107754
Journal article

Thinking outside the box: my reflections on ICID 2024 and CAMO-Net meeting in Cape Town

Wan, Y. (2025). Thinking outside the box: my reflections on ICID 2024 and CAMO-Net meeting in Cape Town. CAMO-Net. Retrieved from https://camonet.org/2025/02/20/dr-yu-wan-in-south-africa/

Website content

2024

Exploring real-world vancomycin target attainment in neonatal intensive care in the context of Staphylococcal infections: a retrospective observational cohort study

Blank, M., Wilson, R. C., Wan, Y., Peters, J., Davies, F., Tyszczuk, L., . . . Rawson, T. M. (2024). Exploring real-world vancomycin target attainment in neonatal intensive care in the context of Staphylococcal infections: a retrospective observational cohort study. JOURNAL OF INFECTION, 89(2). doi:10.1016/j.jinf.2024.106191

DOI
10.1016/j.jinf.2024.106191
Journal article

Integrated Analysis of Patient Networks and Plasmid Genomes to Investigate a Regional, Multispecies Outbreak of Carbapenemase-Producing Enterobacterales Carrying Both blaIMP and mcr-9 Genes.

Wan, Y., Myall, A. C., Boonyasiri, A., Bolt, F., Ledda, A., Mookerjee, S., . . . Davies, F. (2024). Integrated Analysis of Patient Networks and Plasmid Genomes to Investigate a Regional, Multispecies Outbreak of Carbapenemase-Producing Enterobacterales Carrying Both blaIMP and mcr-9 Genes.. The Journal of infectious diseases, 230(1), e159-e170. doi:10.1093/infdis/jiae019

DOI
10.1093/infdis/jiae019
Journal article

Running a queer- and trans-inclusive microbiology faculty search

DOI
10.32942/x2j310
Preprint

Clinical outcomes of <i>Staphylococcus capitis</i> isolation from neonates, England, 2015-2021: a retrospective case-control study

Yuan, J. -M., Nugent, C., Wilson, A., Verlander, N. Q., Alexander, E., Fleming, P., . . . Demirjian, A. (2024). Clinical outcomes of <i>Staphylococcus capitis</i> isolation from neonates, England, 2015-2021: a retrospective case-control study. ARCHIVES OF DISEASE IN CHILDHOOD-FETAL AND NEONATAL EDITION, 109(2), 128-134. doi:10.1136/archdischild-2023-325887

DOI
10.1136/archdischild-2023-325887
Journal article

2023

Building a queer- and trans-inclusive microbiology conference

Gregor, R., Johnston, J., Coe, L. S. Y., Evans, N., Forsythe, D., Jones, R., . . . Weissman, J. L. (2023). Building a queer- and trans-inclusive microbiology conference. MSYSTEMS, 8(5). doi:10.1128/msystems.00433-23

DOI
10.1128/msystems.00433-23
Journal article

IS1-related large- scale deletion of chromosomal regions harbouring the oxygen- insensitive nitroreductase gene<i> nfsB</i> causes nitrofurantoin heteroresistance in<i> Escherichia</i><i> coli</i>

Wan, Y., Sabnis, A., Mumin, Z., Potterill, I., Jauneikaite, E., Brown, C. S., . . . Sriskandan, S. (2023). IS1-related large- scale deletion of chromosomal regions harbouring the oxygen- insensitive nitroreductase gene<i> nfsB</i> causes nitrofurantoin heteroresistance in<i> Escherichia</i><i> coli</i>. MICROBIAL GENOMICS, 9(9). doi:10.1099/mgen.0.001102

DOI
10.1099/mgen.0.001102
Journal article

Whole-genome sequencing reveals widespread presence of<i> Staphylococcus</i><i> capitis</i> NRCS-A clone in neonatal units across the United Kingdom

Wan, Y., Ganner, M., Mumin, Z., Ready, D., Moore, G., Potterill, I., . . . Pichon, B. (2023). Whole-genome sequencing reveals widespread presence of<i> Staphylococcus</i><i> capitis</i> NRCS-A clone in neonatal units across the United Kingdom. JOURNAL OF INFECTION, 87(3), 210-219. doi:10.1016/j.jinf.2023.06.020

DOI
10.1016/j.jinf.2023.06.020
Journal article

Soft Tissue Infection of Immunocompetent Man with Cat-Derived <i>Globicatella</i> Species

Jones, N. K., Coelho, J., Logan, J. M. J., Broughton, K., Hopkins, K. L., Pichon, B., . . . Gouliouris, T. (2023). Soft Tissue Infection of Immunocompetent Man with Cat-Derived <i>Globicatella</i> Species. EMERGING INFECTIOUS DISEASES, 29(8), 1684-1687. doi:10.3201/eid2908.221770

DOI
10.3201/eid2908.221770
Journal article

RECONSTRUCTING AND PREDICTING THE SPATIAL EVOLUTION OF CARBAPENEMASE-PRODUCING ENTEROBACTERIACEAE OUTBREAKS

Myall, A., Wiedermann, M., Vasikasin, P., Klamser, P., Wan, Y., Zachariae, A., . . . Brockmann, D. (2023). RECONSTRUCTING AND PREDICTING THE SPATIAL EVOLUTION OF CARBAPENEMASE-PRODUCING ENTEROBACTERIACEAE OUTBREAKS. INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES, 130, S65. doi:10.1016/j.ijid.2023.04.163

DOI
10.1016/j.ijid.2023.04.163
Journal article

Need for standardized vancomycin dosing for coagulase-negative staphylococci in hospitalized infants.

Harvey, E. J., Ashiru-Oredope, D., Hill, L. F., Demirjian, A., & United Kingdom Health Security Agency Staphylococcus capitis Incident Management Team. (2023). Need for standardized vancomycin dosing for coagulase-negative staphylococci in hospitalized infants.. Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases, 29(1), 10-12. doi:10.1016/j.cmi.2022.09.016

DOI
10.1016/j.cmi.2022.09.016
Journal article

2022

Good IPC practice for the cleaning and handling of incubators and other equipment in neonatal units

Wan, Y. (2022). Good IPC practice for the cleaning and handling of incubators and other equipment in neonatal units. UK Health Security Agency. Retrieved from https://www.gov.uk/

Website content

Improved contact tracing using network analysis and spatial-temporal proximity

Myall, A., Peach, R., Wan, Y., Mookerjee, S., Jauneikaite, E., Bolt, F., . . . Barahona, M. (2022). Improved contact tracing using network analysis and spatial-temporal proximity. INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES, 116, S20. doi:10.1016/j.ijid.2021.12.047

DOI
10.1016/j.ijid.2021.12.047
Journal article

2021

Alterations in chromosomal genes <i>nfsA, nfsB,</i> and <i>ribE</i> are associated with nitrofurantoin resistance in <i>Escherichia coli</i> from the United Kingdom

Wan, Y., Mills, E., Leung, R. C. Y., Vieira, A., Zhi, X., Croucher, N. J., . . . Sriskandan, S. (2021). Alterations in chromosomal genes <i>nfsA, nfsB,</i> and <i>ribE</i> are associated with nitrofurantoin resistance in <i>Escherichia coli</i> from the United Kingdom. MICROBIAL GENOMICS, 7(12). doi:10.1099/mgen.0.000702

DOI
10.1099/mgen.0.000702
Journal article

Characterising contact in disease outbreaks via a network model of spatial-temporal proximity

DOI
10.1101/2021.04.07.21254497
Preprint

2020

GeneMates: an R package for Detecting Horizontal Gene Co-transfer between Bacteria Using Gene-gene Associations Controlled for Population Structure

DOI
10.1101/2020.02.29.970970
Preprint

2019

Search Effectiveness in Nonredundant Sequence Databases: Assessments and Solutions

Chen, Q., Zhang, X., Wan, Y., Zobel, J., & Verspoor, K. (2019). Search Effectiveness in Nonredundant Sequence Databases: Assessments and Solutions. JOURNAL OF COMPUTATIONAL BIOLOGY, 26(6), 605-617. doi:10.1089/cmb.2018.0198

DOI
10.1089/cmb.2018.0198
Journal article

2017

Comparative Analysis of Sequence Clustering Methods for Deduplication of Biological Databases

Chen, Q., Wan, Y., Zhang, X., Lei, Y., Zobel, J., & Verspoor, K. (2017). Comparative Analysis of Sequence Clustering Methods for Deduplication of Biological Databases. Journal of Data and Information Quality, 9(3), 1-27. doi:10.1145/3131611

DOI
10.1145/3131611
Journal article

2016

Evaluation of CD-HIT for constructing non-redundant databases

Chen, Q., Wan, Y., Lei, Y., Zobel, J., & Verspoor, K. (2016). Evaluation of CD-HIT for constructing non-redundant databases. 2016 IEEE INTERNATIONAL CONFERENCE ON BIOINFORMATICS AND BIOMEDICINE (BIBM), 703-706. Retrieved from https://www.webofscience.com/

Journal article

2015